Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5l25_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N GLY 1.A O no hydrogen 3.060 N/A ALA 6.A N PHE 2.A O no hydrogen 3.407 N/A THR 8.A N ILE 4.A O no hydrogen 2.986 N/A THR 8.A OG1 ILE 4.A O no hydrogen 3.111 N/A THR 8.A OG1 LEU 5.A O no hydrogen 2.697 N/A THR 9.A N LEU 5.A O no hydrogen 2.874 N/A THR 9.A OG1 LEU 5.A O no hydrogen 2.611 N/A TYR 10.A N ALA 6.A O no hydrogen 2.976 N/A ILE 11.A N PRO 7.A O no hydrogen 2.842 N/A PHE 12.A N THR 8.A O no hydrogen 2.943 N/A ALA 14.A N TYR 10.A O no hydrogen 3.024 N/A SER 15.A N ILE 11.A O no hydrogen 2.846 N/A SER 15.A N PHE 12.A O no hydrogen 3.243 N/A SER 15.A OG ILE 11.A O no hydrogen 3.038 N/A SER 15.A OG GLN 272.A OE1 no hydrogen 2.962 N/A ALA 16.A N PHE 12.A O no hydrogen 2.941 N/A ILE 20.A N ALA 16.A O no hydrogen 2.708 N/A SER 21.A N ILE 17.A O no hydrogen 2.875 N/A PHE 22.A N PRO 18.A O no hydrogen 2.792 N/A GLY 23.A N VAL 19.A O no hydrogen 2.851 N/A GLU 24.A N ILE 20.A O no hydrogen 2.900 N/A GLN 25.A N SER 21.A O no hydrogen 2.814 N/A LEU 26.A N PHE 22.A O no hydrogen 3.000 N/A LEU 26.A N GLY 23.A O no hydrogen 2.807 N/A GLU 27.A N GLY 23.A O no hydrogen 2.938 N/A ARG 28.A N GLU 24.A O no hydrogen 2.880 N/A SER 29.A N GLN 25.A O no hydrogen 2.887 N/A SER 29.A OG GLN 25.A O no hydrogen 2.905 N/A THR 30.A N LEU 26.A O no hydrogen 2.950 N/A THR 30.A OG1 LEU 26.A O no hydrogen 2.371 N/A ASP 31.A N ARG 28.A O no hydrogen 3.240 N/A VAL 33.A N THR 30.A O no hydrogen 2.825 N/A LEU 34.A N THR 30.A OG1 no hydrogen 3.014 N/A THR 39.A OG1 THR 35.A O no hydrogen 3.353 N/A ALA 41.A N VAL 37.A O no hydrogen 2.958 N/A THR 43.A N LEU 40.A O no hydrogen 3.324 N/A THR 43.A OG1 LEU 40.A O no hydrogen 2.719 N/A ALA 44.A N LEU 40.A O no hydrogen 2.876 N/A ILE 45.A N ALA 41.A O no hydrogen 2.913 N/A CYS 46.A SG SER 42.A O no hydrogen 3.992 N/A GLY 47.A N THR 43.A O no hydrogen 2.933 N/A MET 48.A N ALA 44.A O no hydrogen 2.862 N/A ILE 49.A N ILE 45.A O no hydrogen 2.964 N/A ILE 49.A N CYS 46.A O no hydrogen 3.206 N/A HIS 50.A N CYS 46.A O no hydrogen 3.231 N/A ILE 53.A N SER 273.A OG no hydrogen 2.897 N/A THR 60.A OG1 TYR 233.A OH no hydrogen 2.883 N/A VAL 61.A N ALA 57.A O no hydrogen 3.287 N/A ILE 62.A N GLU 58.A O no hydrogen 2.807 N/A MET 63.A N PRO 59.A O no hydrogen 2.922 N/A TYR 64.A N THR 60.A O no hydrogen 2.888 N/A THR 65.A N VAL 61.A O no hydrogen 2.871 N/A THR 65.A OG1 VAL 61.A O no hydrogen 2.410 N/A PHE 66.A N ILE 62.A O no hydrogen 2.854 N/A MET 67.A N MET 63.A O no hydrogen 2.858 N/A PHE 68.A N TYR 64.A O no hydrogen 2.955 N/A ASN 69.A N THR 65.A O no hydrogen 2.999 N/A PHE 70.A N PHE 66.A O no hydrogen 2.784 N/A ALA 71.A N MET 67.A O no hydrogen 2.951 N/A LYS 72.A N PHE 68.A O no hydrogen 2.889 N/A LEU 81.A N ARG 79.A O no hydrogen 2.603 N/A ALA 84.A N LEU 81.A O no hydrogen 2.887 N/A TRP 85.A N LEU 81.A O no hydrogen 3.230 N/A SER 86.A N PHE 82.A O no hydrogen 2.997 N/A SER 86.A OG LEU 83.A O no hydrogen 2.927 N/A SER 86.A OG GLY 262.A O no hydrogen 2.813 N/A TRP 88.A N ALA 84.A O no hydrogen 3.007 N/A VAL 89.A N TRP 85.A O no hydrogen 2.952 N/A CYS 90.A N SER 86.A O no hydrogen 2.894 N/A CYS 90.A SG THR 258.A O no hydrogen 3.048 N/A VAL 91.A N GLY 87.A O no hydrogen 2.969 N/A TRP 92.A NE1 ILE 219.A O no hydrogen 2.765 N/A THR 93.A N VAL 89.A O no hydrogen 2.948 N/A THR 93.A OG1 VAL 89.A O no hydrogen 2.786 N/A ALA 94.A N CYS 90.A O no hydrogen 2.883 N/A LEU 95.A N VAL 91.A O no hydrogen 2.964 N/A MET 96.A N TRP 92.A O no hydrogen 2.876 N/A LEU 97.A N THR 93.A O no hydrogen 3.033 N/A PHE 98.A N ALA 94.A O no hydrogen 2.832 N/A VAL 99.A N LEU 95.A O no hydrogen 2.858 N/A LEU 100.A N MET 96.A O no hydrogen 3.015 N/A GLY 104.A N LEU 100.A O no hydrogen 2.918 N/A ALA 105.A N ALA 101.A O no hydrogen 2.872 N/A CYS 106.A N ILE 102.A O no hydrogen 2.957 N/A SER 107.A N GLY 104.A O no hydrogen 3.235 N/A ILE 108.A N ALA 105.A O no hydrogen 3.350 N/A GLY 117.A N PHE 112.A O no hydrogen 2.742 N/A LEU 119.A N ALA 116.A O no hydrogen 3.032 N/A GLY 121.A N GLY 117.A O no hydrogen 2.964 N/A LEU 123.A N LEU 119.A O no hydrogen 2.945 N/A ILE 124.A N PHE 120.A O no hydrogen 2.990 N/A ALA 125.A N GLY 121.A O no hydrogen 3.489 N/A MET 126.A N LEU 122.A O no hydrogen 2.861 N/A LEU 127.A N LEU 123.A O no hydrogen 2.980 N/A PHE 128.A N ILE 124.A O no hydrogen 2.815 N/A MET 129.A N ALA 125.A O no hydrogen 2.882 N/A GLN 130.A N MET 126.A O no hydrogen 3.003 N/A GLN 131.A N LEU 127.A O no hydrogen 2.887 N/A ALA 132.A N MET 129.A O no hydrogen 3.072 N/A ILE 133.A N MET 129.A O no hydrogen 2.956 N/A LYS 134.A N GLN 130.A O no hydrogen 2.884 N/A LEU 136.A N ALA 132.A O no hydrogen 2.894 N/A VAL 137.A N ILE 133.A O no hydrogen 2.866 N/A ASP 138.A N LYS 134.A O no hydrogen 2.884 N/A ASP 138.A N GLY 135.A O no hydrogen 3.278 N/A GLU 139.A N LEU 136.A O no hydrogen 3.480 N/A PHE 140.A N VAL 137.A O no hydrogen 3.417 N/A ARG 145.A N ILE 142.A O no hydrogen 2.918 N/A ASN 147.A N PRO 143.A O no hydrogen 2.522 N/A PHE 153.A N LEU 150.A O no hydrogen 3.255 N/A SER 156.A N PHE 153.A O no hydrogen 3.391 N/A ASN 161.A N TRP 157.A O no hydrogen 3.275 N/A GLY 162.A N PHE 159.A O no hydrogen 2.839 N/A PHE 164.A N ALA 160.A O no hydrogen 3.151 N/A ALA 165.A N ASN 161.A O no hydrogen 2.923 N/A VAL 167.A N GLY 162.A O no hydrogen 3.374 N/A VAL 167.A N MET 163.A O no hydrogen 3.028 N/A SER 169.A N ALA 165.A O no hydrogen 2.965 N/A PHE 170.A N LEU 166.A O no hydrogen 3.043 N/A GLY 171.A N VAL 167.A O no hydrogen 2.871 N/A LEU 172.A N LEU 168.A O no hydrogen 2.930 N/A LEU 173.A N SER 169.A O no hydrogen 2.976 N/A LEU 174.A N PHE 170.A O no hydrogen 2.946 N/A THR 175.A N GLY 171.A O no hydrogen 2.983 N/A THR 175.A OG1 GLY 171.A O no hydrogen 2.756 N/A GLY 176.A N LEU 172.A O no hydrogen 2.806 N/A GLY 176.A N LEU 173.A O no hydrogen 3.245 N/A LEU 177.A N LEU 173.A O no hydrogen 3.000 N/A LEU 177.A N LEU 174.A O no hydrogen 3.097 N/A SER 179.A N GLY 176.A O no hydrogen 2.954 N/A SER 179.A OG ALA 197.A O no hydrogen 3.062 N/A LYS 181.A N LEU 177.A O no hydrogen 3.005 N/A ALA 182.A N ARG 178.A O no hydrogen 2.844 N/A TRP 185.A N ALA 182.A O no hydrogen 3.432 N/A ARG 186.A NH2 TYR 187.A OH no hydrogen 3.251 N/A ILE 196.A N LEU 192.A O no hydrogen 3.105 N/A ALA 197.A N ARG 193.A O no hydrogen 2.858 N/A ASP 198.A N SER 194.A O no hydrogen 2.865 N/A GLY 200.A N ALA 197.A O no hydrogen 2.905 N/A LEU 203.A N TYR 199.A O no hydrogen 2.784 N/A MET 204.A N GLY 200.A O no hydrogen 2.888 N/A VAL 205.A N VAL 201.A O no hydrogen 2.909 N/A LEU 206.A N PRO 202.A O no hydrogen 3.036 N/A VAL 207.A N LEU 203.A O no hydrogen 2.844 N/A TRP 208.A N MET 204.A O no hydrogen 2.924 N/A TRP 208.A NE1 THR 175.A OG1 no hydrogen 2.250 N/A THR 209.A N VAL 205.A O no hydrogen 2.888 N/A THR 209.A OG1 VAL 205.A O no hydrogen 2.272 N/A GLY 210.A N LEU 206.A O no hydrogen 2.879 N/A GLY 210.A N VAL 207.A O no hydrogen 3.071 N/A VAL 211.A N VAL 207.A O no hydrogen 2.861 N/A SER 212.A N TRP 208.A O no hydrogen 2.886 N/A SER 212.A OG THR 209.A O no hydrogen 3.103 N/A ILE 214.A N VAL 211.A O no hydrogen 3.432 N/A ILE 220.A N ILE 216.A O no hydrogen 3.301 N/A GLY 221.A N VAL 217.A O no hydrogen 2.965 N/A ALA 222.A N ILE 219.A O no hydrogen 3.469 N/A SER 227.A N PHE 223.A O no hydrogen 2.807 N/A SER 227.A OG PHE 223.A O no hydrogen 3.033 N/A SER 227.A OG ILE 224.A O no hydrogen 2.771 N/A MET 228.A N ILE 224.A O no hydrogen 2.936 N/A ILE 229.A N PRO 225.A O no hydrogen 2.854 N/A ALA 230.A N ALA 226.A O no hydrogen 2.888 N/A VAL 231.A N SER 227.A O no hydrogen 3.484 N/A LEU 232.A N MET 228.A O no hydrogen 2.953 N/A TYR 233.A N ILE 229.A O no hydrogen 2.850 N/A TYR 233.A OH THR 60.A OG1 no hydrogen 2.883 N/A TYR 234.A N ALA 230.A O no hydrogen 2.842 N/A PHE 235.A N LEU 232.A O no hydrogen 2.965 N/A ASP 236.A N LEU 232.A O no hydrogen 3.016 N/A HIS 237.A N TYR 233.A O no hydrogen 2.862 N/A SER 238.A OG TYR 234.A O no hydrogen 3.241 N/A VAL 239.A N PHE 235.A O no hydrogen 2.835 N/A ALA 240.A N ASP 236.A O no hydrogen 2.967 N/A SER 241.A OG GLN 245.A OE1 no hydrogen 2.949 N/A GLN 242.A N SER 238.A O no hydrogen 2.856 N/A ALA 244.A N ALA 240.A O no hydrogen 2.871 N/A GLN 245.A N SER 241.A O no hydrogen 3.286 N/A GLN 246.A NE2 GLN 242.A O no hydrogen 2.754 N/A PHE 249.A N GLN 246.A O no hydrogen 3.238 N/A GLY 255.A N LEU 252.A O no hydrogen 3.048 N/A THR 258.A N LEU 254.A O no hydrogen 2.815 N/A THR 258.A OG1 GLY 255.A O no hydrogen 2.392 N/A LEU 259.A N GLY 255.A O no hydrogen 3.273 N/A CYS 261.A N LEU 257.A O no hydrogen 2.879 N/A GLY 262.A N THR 258.A O no hydrogen 2.830 N/A LEU 263.A N LEU 259.A O no hydrogen 3.116 N/A LEU 263.A N MET 260.A O no hydrogen 2.900 N/A LEU 264.A N MET 260.A O no hydrogen 3.170 N/A GLY 265.A N CYS 261.A O no hydrogen 3.345 N/A SER 266.A OG GLY 55.A O no hydrogen 3.186 N/A ASN 267.A N GLY 55.A O no hydrogen 3.309 N/A VAL 269.A N ILE 53.A O no hydrogen 2.485 N/A HIS 276.A N SER 273.A O no hydrogen 3.024 N/A THR 277.A N PRO 274.A O no hydrogen 3.321 N/A THR 277.A OG1 ALA 244.A O no hydrogen 3.450 N/A THR 277.A OG1 SER 273.A O no hydrogen 3.511 N/A SER 279.A OG HIS 276.A O no hydrogen 3.554 N/A LEU 280.A N THR 277.A O no hydrogen 3.306 N/A GLN 288.A NE2 HIS 276.A NE2 no hydrogen 3.482 N/A SER 289.A N ASN 285.A O no hydrogen 2.914 N/A SER 289.A OG ASN 285.A O no hydrogen 3.207 N/A THR 290.A N LEU 286.A O no hydrogen 2.821 N/A THR 290.A OG1 LEU 286.A O no hydrogen 2.313 N/A MET 291.A N LEU 287.A O no hydrogen 2.972 N/A VAL 292.A N GLN 288.A O no hydrogen 2.800 N/A GLY 293.A N SER 289.A O no hydrogen 2.918 N/A GLY 294.A N THR 290.A O no hydrogen 2.907 N/A CYS 295.A N MET 291.A O no hydrogen 2.836 N/A VAL 296.A N GLY 293.A O no hydrogen 3.324 N/A ALA 298.A N GLY 294.A O no hydrogen 2.836 N/A MET 299.A N CYS 295.A O no hydrogen 2.847 N/A ILE 301.A N ALA 297.A O no hydrogen 2.858 N/A LEU 302.A N ALA 298.A O no hydrogen 2.545 N/A LYS 303.A N MET 299.A O no hydrogen 3.246 N/A SER 305.A OG PHE 164.A O no hydrogen 2.222 N/A SER 305.A OG ALA 165.A O no hydrogen 3.437 N/A GLY 309.A N SER 305.A O no hydrogen 3.398 N/A TYR 310.A N VAL 306.A O no hydrogen 2.962 N/A TYR 310.A OH VAL 201.A O no hydrogen 3.117 N/A PHE 311.A N LEU 307.A O no hydrogen 2.838 N/A ALA 312.A N TRP 308.A O no hydrogen 2.910 N/A PHE 313.A N GLY 309.A O no hydrogen 2.908 N/A MET 314.A N TYR 310.A O no hydrogen 2.691 N/A ALA 315.A N PHE 311.A O no hydrogen 2.959 N/A ILE 316.A N ALA 312.A O no hydrogen 2.859 N/A GLU 317.A N PHE 313.A O no hydrogen 2.800 N/A SER 318.A OG ALA 315.A O no hydrogen 3.549 N/A LEU 319.A N ILE 316.A O no hydrogen 2.879 N/A ASN 322.A ND2 GLU 118.A O no hydrogen 3.291 N/A GLN 323.A N GLU 118.A OE2 no hydrogen 2.982 N/A TRP 325.A N ASN 322.A O no hydrogen 3.158 N/A TRP 325.A N ASN 322.A OD1 no hydrogen 2.743 N/A GLU 326.A N ASN 322.A O no hydrogen 3.220 N/A ARG 327.A N GLN 323.A O no hydrogen 2.891 N/A ILE 328.A N PHE 324.A O no hydrogen 2.855 N/A LEU 329.A N TRP 325.A O no hydrogen 2.886 N/A LEU 330.A N GLU 326.A O no hydrogen 2.935 N/A LEU 331.A N ILE 328.A O no hydrogen 3.392 N/A PHE 332.A N ILE 328.A O no hydrogen 2.998 N/A ALA 334.A N THR 333.A OG1 no hydrogen 2.763 N/A PHE 339.A N SER 336.A O no hydrogen 3.353 N/A LYS 340.A N ARG 337.A O no hydrogen 2.905 N/A VAL 341.A N ARG 338.A O no hydrogen 3.213 N/A LEU 342.A N LYS 340.A O no hydrogen 2.843 N/A ILE 356.A N PHE 353.A O no hydrogen 2.807 N/A ALA 357.A N LYS 354.A O no hydrogen 3.071 N/A MET 358.A N THR 355.A O no hydrogen 3.313 N/A THR 360.A OG1 ALA 357.A O no hydrogen 3.265 N/A LEU 361.A N MET 358.A O no hydrogen 3.193 N/A PHE 362.A N PHE 359.A O no hydrogen 2.342 N/A THR 364.A N THR 360.A O no hydrogen 2.805 N/A THR 364.A OG1 THR 360.A O no hydrogen 3.202 N/A THR 365.A N LEU 361.A O no hydrogen 2.846 N/A THR 365.A OG1 LEU 361.A O no hydrogen 2.410 N/A TYR 366.A N PHE 362.A O no hydrogen 2.899 N/A LEU 367.A N GLN 363.A O no hydrogen 2.931 N/A LEU 368.A N THR 364.A O no hydrogen 2.806 N/A ILE 369.A N THR 365.A O no hydrogen 2.871 N/A CYS 370.A N TYR 366.A O no hydrogen 2.930 N/A CYS 370.A SG TYR 366.A O no hydrogen 3.156 N/A PHE 371.A N LEU 367.A O no hydrogen 2.791 N/A GLY 372.A N LEU 368.A O no hydrogen 2.878 N/A LEU 373.A N ILE 369.A O no hydrogen 2.887 N/A THR 374.A N CYS 370.A O no hydrogen 2.837 N/A THR 374.A N PHE 371.A O no hydrogen 3.217 N/A THR 374.A OG1 CYS 370.A O no hydrogen 3.161 N/A THR 374.A OG1 PHE 371.A O no hydrogen 2.699 N/A ILE 376.A N LEU 373.A O no hydrogen 3.305 N/A ALA 379.A N PRO 377.A O no hydrogen 2.532 N/A GLY 380.A N ILE 376.A O no hydrogen 2.554 N/A MET 382.A N ILE 378.A O no hydrogen 3.184 N/A PHE 383.A N VAL 381.A O no hydrogen 3.122 N/A ILE 387.A N PHE 383.A O no hydrogen 3.516 N/A MET 388.A N PRO 384.A O no hydrogen 3.055 N/A PHE 389.A N LEU 385.A O no hydrogen 2.629 N/A LEU 390.A N MET 386.A O no hydrogen 3.222 N/A ILE 391.A N ILE 387.A O no hydrogen 2.920 N/A ARG 394.A N LEU 390.A O no hydrogen 3.125 N/A ARG 394.A NH1 PHE 362.A O no hydrogen 3.368 N/A