Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5m5a_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N LYS 1.A O no hydrogen 3.225 N/A LEU 7.A N TYR 3.A O no hydrogen 2.859 N/A LYS 8.A N ASP 4.A O no hydrogen 3.279 N/A LYS 8.A N GLU 5.A O no hydrogen 3.344 N/A LYS 8.A NZ GLU 5.A OE1 no hydrogen 2.766 N/A TYR 9.A N LEU 6.A O no hydrogen 2.982 N/A TYR 10.A N LEU 6.A O no hydrogen 3.025 N/A TYR 10.A OH HIS 73.A ND1 no hydrogen 2.900 N/A GLU 11.A N CYS 28.A O no hydrogen 2.996 N/A HIS 13.A N LEU 26.A O no hydrogen 2.633 N/A GLU 14.A N GLU 14.A OE1 no hydrogen 2.939 N/A ILE 16.A N VAL 24.A O no hydrogen 2.878 N/A GLY 17.A N VAL 24.A O no hydrogen 3.441 N/A GLY 19.A N ALA 22.A O no hydrogen 2.998 N/A LYS 23.A N ILE 40.A O no hydrogen 3.133 N/A VAL 24.A N GLY 17.A O no hydrogen 2.923 N/A LYS 25.A N ILE 38.A O no hydrogen 2.933 N/A LEU 26.A N GLU 14.A O no hydrogen 2.867 N/A ALA 27.A N VAL 36.A O no hydrogen 2.969 N/A CYS 28.A N GLU 11.A O no hydrogen 2.902 N/A CYS 28.A SG GLU 34.A O no hydrogen 3.831 N/A HIS 29.A N GLU 34.A O no hydrogen 2.812 N/A HIS 29.A ND1 THR 32.A OG1 no hydrogen 2.598 N/A HIS 29.A NE2 HIS 294.A NE2 no hydrogen 3.061 N/A ILE 30.A N TYR 9.A O no hydrogen 2.948 N/A THR 32.A N HIS 29.A ND1 no hydrogen 3.267 N/A THR 32.A N HIS 29.A O no hydrogen 3.302 N/A THR 32.A OG1 HIS 29.A ND1 no hydrogen 2.598 N/A GLY 33.A N HIS 29.A O no hydrogen 2.900 N/A GLU 34.A N THR 32.A OG1 no hydrogen 3.285 N/A VAL 36.A N ALA 27.A O no hydrogen 2.696 N/A ALA 37.A N LEU 85.A O no hydrogen 2.760 N/A ILE 38.A N LYS 25.A O no hydrogen 2.816 N/A LYS 39.A N MET 83.A O no hydrogen 2.784 N/A LYS 39.A NZ GLU 56.A OE2 no hydrogen 3.148 N/A ILE 40.A N LYS 23.A O no hydrogen 2.798 N/A MET 41.A N ILE 81.A O no hydrogen 2.958 N/A LYS 43.A N ASN 79.A O no hydrogen 2.681 N/A LYS 43.A NZ GLU 76.A OE2 no hydrogen 2.774 N/A LYS 43.A NZ THR 77.A O no hydrogen 2.856 N/A LYS 43.A NZ ALA 78.A O no hydrogen 3.127 N/A ASN 44.A ND2 ASN 79.A OD1 no hydrogen 3.341 N/A THR 45.A N ASP 42.A OD1 no hydrogen 3.062 N/A LEU 50.A N GLY 47.A O no hydrogen 3.265 N/A ARG 52.A N ASP 49.A O no hydrogen 2.716 N/A ILE 53.A N ASP 49.A O no hydrogen 3.204 N/A LYS 54.A N LEU 50.A O no hydrogen 2.850 N/A LYS 54.A NZ GLU 76.A OE1 no hydrogen 2.843 N/A THR 55.A N PRO 51.A O no hydrogen 3.077 N/A THR 55.A OG1 PRO 51.A O no hydrogen 3.131 N/A GLU 56.A N ARG 52.A O no hydrogen 3.043 N/A ILE 57.A N ILE 53.A O no hydrogen 2.933 N/A GLU 58.A N LYS 54.A O no hydrogen 3.286 N/A ALA 59.A N THR 55.A O no hydrogen 2.888 N/A LEU 60.A N GLU 56.A O no hydrogen 3.096 N/A LYS 61.A N ILE 57.A O no hydrogen 3.083 N/A LYS 61.A NZ GLU 58.A OE2 no hydrogen 3.183 N/A ASN 62.A N GLU 58.A O no hydrogen 3.281 N/A ASN 62.A N ALA 59.A O no hydrogen 2.881 N/A ASN 62.A ND2 TYR 127.A OH no hydrogen 3.470 N/A LEU 63.A N LEU 60.A O no hydrogen 3.299 N/A ARG 64.A N TYR 121.A OH no hydrogen 3.002 N/A ARG 64.A NE ASN 259.A O no hydrogen 2.771 N/A ARG 64.A NH1 GLN 70.A OE1 no hydrogen 3.138 N/A HIS 65.A NE2 TRP 255.A O no hydrogen 2.749 N/A GLN 66.A N GLN 66.A OE1 no hydrogen 2.692 N/A GLN 66.A NE2 GLN 256.A O no hydrogen 3.065 N/A HIS 67.A N HIS 65.A ND1 no hydrogen 3.085 N/A HIS 67.A ND1 LEU 145.A O no hydrogen 2.925 N/A ILE 68.A N HIS 65.A O no hydrogen 3.013 N/A CYS 69.A N LEU 147.A O no hydrogen 3.016 N/A CYS 69.A SG GLU 86.A O no hydrogen 3.055 N/A GLN 70.A N GLU 86.A OE1 no hydrogen 2.991 N/A GLN 70.A NE2 LEU 71.A O no hydrogen 2.922 N/A TYR 72.A N VAL 84.A O no hydrogen 2.705 N/A HIS 73.A ND1 TYR 10.A OH no hydrogen 2.900 N/A VAL 74.A N TYR 292.A O no hydrogen 2.839 N/A LEU 75.A N PHE 82.A O no hydrogen 2.934 N/A THR 77.A N LYS 80.A O no hydrogen 2.865 N/A THR 77.A OG1 ASP 2.A OD1 no hydrogen 2.974 N/A THR 77.A OG1 LYS 80.A O no hydrogen 3.510 N/A ASN 79.A N ASP 2.A OD1 no hydrogen 3.288 N/A ASN 79.A ND2 ASP 2.A OD1 no hydrogen 3.035 N/A ASN 79.A ND2 ASP 2.A OD2 no hydrogen 2.995 N/A LYS 80.A N THR 77.A OG1 no hydrogen 3.241 N/A LYS 80.A NZ ASP 42.A OD2 no hydrogen 3.208 N/A ILE 81.A N MET 41.A O no hydrogen 2.932 N/A PHE 82.A N LEU 75.A O no hydrogen 2.837 N/A MET 83.A N LYS 39.A O no hydrogen 2.773 N/A VAL 84.A N HIS 73.A O no hydrogen 2.787 N/A LEU 85.A N ALA 37.A O no hydrogen 2.742 N/A GLU 86.A N GLN 70.A O no hydrogen 2.886 N/A GLY 90.A N PHE 139.A O no hydrogen 2.827 N/A GLY 91.A N CYS 88.A O no hydrogen 3.275 N/A LEU 93.A N LEU 137.A O no hydrogen 2.767 N/A PHE 94.A N PRO 134.A O no hydrogen 3.267 N/A TYR 96.A N GLU 92.A O no hydrogen 3.221 N/A TYR 96.A OH GLU 107.A OE2 no hydrogen 2.508 N/A ILE 97.A N LEU 93.A O no hydrogen 2.960 N/A ILE 98.A N PHE 94.A O no hydrogen 3.100 N/A SER 99.A N ASP 95.A O no hydrogen 3.091 N/A SER 99.A OG ASP 95.A O no hydrogen 3.479 N/A SER 99.A OG TYR 96.A O no hydrogen 2.970 N/A GLN 100.A N TYR 96.A O no hydrogen 3.197 N/A ASP 101.A N ILE 98.A O no hydrogen 3.293 N/A LEU 103.A N LEU 184.A O no hydrogen 2.835 N/A GLU 107.A N SER 104.A OG no hydrogen 3.140 N/A THR 108.A N SER 104.A O no hydrogen 2.790 N/A THR 108.A OG1 LEU 103.A O no hydrogen 3.552 N/A THR 108.A OG1 SER 104.A O no hydrogen 2.886 N/A ARG 109.A N GLU 105.A O no hydrogen 2.973 N/A ARG 109.A NE TRP 244.A O no hydrogen 2.711 N/A ARG 109.A NH2 GLU 105.A OE2.A no hydrogen 2.860 N/A ARG 109.A NH2 TRP 244.A O no hydrogen 3.225 N/A VAL 110.A N GLU 106.A O no hydrogen 3.259 N/A VAL 111.A N GLU 107.A O no hydrogen 3.077 N/A PHE 112.A N THR 108.A O no hydrogen 2.691 N/A ARG 113.A N ARG 109.A O no hydrogen 2.872 N/A ARG 113.A NH1 TYR 251.A O no hydrogen 3.131 N/A ARG 113.A NH2 ILE 245.A O no hydrogen 3.032 N/A ARG 113.A NH2 TYR 251.A O no hydrogen 3.086 N/A GLN 114.A N VAL 111.A O no hydrogen 3.097 N/A GLN 114.A NE2 VAL 110.A O no hydrogen 3.036 N/A ILE 115.A N VAL 111.A O no hydrogen 3.307 N/A VAL 116.A N PHE 112.A O no hydrogen 2.908 N/A SER 117.A N ARG 113.A O no hydrogen 3.040 N/A SER 117.A OG GLU 254.A O no hydrogen 2.863 N/A ALA 118.A N GLN 114.A O no hydrogen 2.988 N/A VAL 119.A N ILE 115.A O no hydrogen 3.009 N/A ALA 120.A N VAL 116.A O no hydrogen 2.818 N/A TYR 121.A N SER 117.A O no hydrogen 3.146 N/A VAL 122.A N ALA 118.A O no hydrogen 2.948 N/A HIS 123.A N VAL 119.A O no hydrogen 2.914 N/A HIS 123.A NE2 ASP 173.A OD2 no hydrogen 2.805 N/A SER 124.A N ALA 120.A O no hydrogen 2.764 N/A SER 124.A OG TYR 121.A O no hydrogen 2.567 N/A GLN 125.A N TYR 121.A O no hydrogen 2.925 N/A GLN 125.A NE2 ASN 62.A O no hydrogen 3.110 N/A GLY 126.A N HIS 123.A O no hydrogen 2.906 N/A TYR 127.A N VAL 122.A O no hydrogen 2.993 N/A ALA 128.A N ALA 154.A O no hydrogen 2.994 N/A HIS 129.A N ASP 173.A OD2 no hydrogen 2.895 N/A HIS 129.A NE2 ILE 148.A O no hydrogen 2.869 N/A ARG 130.A N ASP 173.A OD1 no hydrogen 3.074 N/A ASP 131.A N HIS 129.A ND1 no hydrogen 3.202 N/A LYS 133.A NZ ASP 131.A OD2 no hydrogen 3.378 N/A GLU 135.A N GLU 135.A OE1 no hydrogen 2.744 N/A ASN 136.A N LYS 133.A O no hydrogen 2.959 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.728 N/A ASN 136.A ND2 ASP 131.A OD2 no hydrogen 3.122 N/A LEU 138.A N LYS 146.A O no hydrogen 2.880 N/A PHE 139.A N GLY 91.A O no hydrogen 2.784 N/A ASP 140.A N LYS 144.A O no hydrogen 2.798 N/A TYR 142.A N ASP 140.A OD1 no hydrogen 2.865 N/A HIS 143.A N ASP 140.A O no hydrogen 2.991 N/A LYS 144.A N ASP 140.A OD1 no hydrogen 2.912 N/A LEU 145.A N GLN 114.A OE1 no hydrogen 2.920 N/A LYS 146.A N LEU 138.A O no hydrogen 2.728 N/A LYS 146.A NZ GLU 86.A OE2 no hydrogen 2.540 N/A LYS 146.A NZ ASP 140.A OD2 no hydrogen 3.031 N/A LEU 147.A N HIS 67.A O no hydrogen 2.859 N/A ILE 148.A N ASN 136.A O no hydrogen 2.973 N/A GLY 151.A N ASP 149.A OD1 no hydrogen 3.302 N/A CYS 153.A N PHE 150.A O no hydrogen 3.149 N/A CYS 153.A SG PHE 150.A O no hydrogen 3.504 N/A ALA 154.A N ALA 128.A O no hydrogen 3.058 N/A TYR 158.A N SER 155.A O no hydrogen 2.955 N/A ALA 159.A N LEU 156.A O no hydrogen 3.107 N/A GLU 162.A N GLU 162.A OE1 no hydrogen 2.867 N/A ILE 164.A N ALA 160.A O no hydrogen 2.983 N/A GLN 165.A N PRO 161.A O no hydrogen 2.947 N/A GLY 166.A N LEU 163.A O no hydrogen 3.178 N/A LYS 167.A N GLU 162.A O no hydrogen 2.936 N/A GLU 171.A N GLU 171.A OE1.A no hydrogen 2.891 N/A ALA 172.A N LEU 168.A O no hydrogen 3.104 N/A ASP 173.A N GLY 169.A O no hydrogen 3.194 N/A ASP 173.A N SER 170.A O no hydrogen 2.988 N/A VAL 174.A N SER 170.A O no hydrogen 3.243 N/A TRP 175.A N GLU 171.A O no hydrogen 3.183 N/A SER 176.A N ALA 172.A O no hydrogen 3.177 N/A SER 176.A OG TYR 158.A O no hydrogen 2.691 N/A SER 176.A OG ALA 172.A O no hydrogen 3.322 N/A MET 177.A N ASP 173.A O no hydrogen 2.961 N/A GLY 178.A N VAL 174.A O no hydrogen 2.932 N/A ILE 179.A N TRP 175.A O no hydrogen 3.023 N/A LEU 180.A N SER 176.A O no hydrogen 2.905 N/A LEU 181.A N MET 177.A O no hydrogen 2.778 N/A TYR 182.A N GLY 178.A O no hydrogen 3.051 N/A TYR 182.A OH ASP 209.A O no hydrogen 2.660 N/A VAL 183.A N ILE 179.A O no hydrogen 2.919 N/A LEU 184.A N LEU 180.A O no hydrogen 2.916 N/A MET 185.A N LEU 181.A O no hydrogen 3.153 N/A CYS 186.A N TYR 182.A O no hydrogen 2.737 N/A GLY 187.A N VAL 183.A O no hydrogen 2.743 N/A ASN 195.A N ASP 193.A OD1 no hydrogen 2.892 N/A MET 197.A N ASN 195.A OD1 no hydrogen 2.845 N/A ALA 198.A N ASN 195.A OD1 no hydrogen 3.335 N/A LEU 199.A N ASN 195.A O no hydrogen 2.988 N/A TYR 200.A N VAL 196.A O no hydrogen 2.931 N/A LYS 201.A N MET 197.A O no hydrogen 2.974 N/A LYS 202.A N ALA 198.A O no hydrogen 3.040 N/A LYS 202.A NZ ASP 192.A O no hydrogen 3.118 N/A LYS 202.A NZ ASP 193.A OD2 no hydrogen 2.689 N/A ILE 203.A N LEU 199.A O no hydrogen 2.966 N/A MET 204.A N TYR 200.A O no hydrogen 2.936 N/A ARG 205.A N LYS 201.A O no hydrogen 2.947 N/A GLY 206.A N LYS 202.A O no hydrogen 3.046 N/A TRP 213.A NE1 MET 185.A O no hydrogen 2.825 N/A LEU 214.A N PRO 211.A O no hydrogen 3.333 N/A SER 215.A N GLU 105.A OE2.B no hydrogen 2.836 N/A SER 215.A OG GLU 105.A OE1.A no hydrogen 2.713 N/A SER 215.A OG GLU 105.A OE1.B no hydrogen 2.664 N/A SER 215.A OG GLU 105.A OE2.B no hydrogen 3.214 N/A SER 215.A OG SER 218.A OG.A no hydrogen 3.066 N/A SER 218.A N SER 215.A OG no hydrogen 3.272 N/A SER 218.A OG.A GLU 105.A OE1.B no hydrogen 2.413 N/A SER 218.A OG.A SER 215.A OG no hydrogen 3.066 N/A SER 218.A OG.B GLU 105.A OE2.B no hydrogen 3.513 N/A SER 218.A OG.B SER 215.A O no hydrogen 2.712 N/A ILE 219.A N SER 215.A O no hydrogen 3.078 N/A LEU 220.A N PRO 216.A O no hydrogen 2.911 N/A LEU 221.A N SER 217.A O no hydrogen 3.011 N/A LEU 222.A N SER 218.A O no hydrogen 2.876 N/A GLN 223.A N ILE 219.A O no hydrogen 3.010 N/A GLN 224.A N LEU 220.A O no hydrogen 2.975 N/A MET 225.A N LEU 221.A O no hydrogen 2.922 N/A LEU 226.A N LEU 222.A O no hydrogen 2.861 N/A GLN 227.A NE2 GLN 223.A O no hydrogen 2.938 N/A LYS 231.A N ASP 229.A OD1 no hydrogen 3.118 N/A LYS 232.A N ASP 229.A O no hydrogen 3.092 N/A ARG 233.A N ASP 229.A O no hydrogen 3.256 N/A ARG 233.A NE GLN 227.A O no hydrogen 2.852 N/A ARG 233.A NH1 GLU 162.A OE1 no hydrogen 3.464 N/A ARG 233.A NH1 GLU 162.A OE2 no hydrogen 2.747 N/A ARG 233.A NH1 GLU 171.A O no hydrogen 2.818 N/A ARG 233.A NH2 GLU 162.A OE1 no hydrogen 2.878 N/A ARG 233.A NH2 GLN 227.A O no hydrogen 2.746 N/A ILE 234.A N GLN 224.A O no hydrogen 2.952 N/A LYS 237.A NZ ASN 238.A OD1 no hydrogen 3.164 N/A LEU 239.A N SER 235.A O no hydrogen 3.111 N/A LEU 239.A N MET 236.A O no hydrogen 3.116 N/A LEU 240.A N MET 236.A O no hydrogen 3.191 N/A LEU 240.A N LYS 237.A O no hydrogen 3.283 N/A HIS 242.A N LEU 239.A O no hydrogen 3.302 N/A HIS 242.A NE2 GLN 224.A OE1 no hydrogen 2.604 N/A TRP 244.A N HIS 242.A ND1 no hydrogen 3.223 N/A TRP 244.A NE1 GLU 105.A OE1.B no hydrogen 3.376 N/A MET 246.A N HIS 242.A O no hydrogen 2.802 N/A GLN 247.A N PRO 243.A O no hydrogen 3.014 N/A TYR 249.A N MET 246.A O no hydrogen 3.028 N/A ASN 250.A N MET 246.A O no hydrogen 2.743 N/A VAL 253.A N LEU 240.A O no hydrogen 2.892 N/A SER 257.A OG ARG 64.A O no hydrogen 2.635 N/A SER 257.A OG ASN 259.A OD1 no hydrogen 2.869 N/A LYS 258.A N GLN 66.A OE1 no hydrogen 2.746 N/A LYS 258.A NZ GLU 254.A OE1 no hydrogen 3.032 N/A ASN 259.A N SER 257.A OG no hydrogen 3.369 N/A ASP 265.A N TYR 299.A OH no hydrogen 2.737 N/A CYS 268.A N ASP 265.A OD2 no hydrogen 3.173 N/A CYS 268.A SG ASP 265.A OD2 no hydrogen 3.349 N/A VAL 269.A N ASP 265.A O no hydrogen 3.049 N/A THR 270.A N ASP 266.A O no hydrogen 2.807 N/A THR 270.A OG1 ASP 266.A O no hydrogen 2.895 N/A GLU 271.A N ASP 267.A O no hydrogen 2.861 N/A LEU 272.A N CYS 268.A O no hydrogen 3.015 N/A SER 273.A N VAL 269.A O no hydrogen 3.022 N/A SER 273.A OG VAL 269.A O no hydrogen 3.567 N/A SER 273.A OG THR 270.A O no hydrogen 2.879 N/A VAL 274.A N THR 270.A O no hydrogen 2.989 N/A HIS 275.A N GLU 271.A O no hydrogen 2.905 N/A HIS 276.A N LEU 272.A O no hydrogen 2.637 N/A ARG 277.A N VAL 274.A O no hydrogen 3.407 N/A ASN 278.A N SER 273.A O no hydrogen 2.924 N/A ARG 280.A NE THR 270.A OG1 no hydrogen 3.147 N/A ARG 280.A NH2 ASP 266.A O no hydrogen 3.190 N/A ARG 280.A NH2 THR 270.A OG1 no hydrogen 3.359 N/A GLN 281.A N ASN 279.A OD1 no hydrogen 2.767 N/A GLN 281.A NE2 ASP 285.A OD1 no hydrogen 2.923 N/A THR 282.A N ASN 279.A OD1 no hydrogen 3.232 N/A MET 283.A N ASN 279.A O no hydrogen 3.144 N/A GLU 284.A N ARG 280.A O no hydrogen 3.019 N/A ASP 285.A N GLN 281.A O no hydrogen 3.022 N/A LEU 286.A N THR 282.A O no hydrogen 2.754 N/A ILE 287.A N MET 283.A O no hydrogen 2.754 N/A SER 288.A N GLU 284.A O no hydrogen 2.845 N/A SER 288.A OG GLU 284.A O no hydrogen 2.660 N/A LEU 289.A N LEU 286.A O no hydrogen 3.231 N/A TRP 290.A N ILE 287.A O no hydrogen 3.011 N/A TYR 292.A N THR 296.A OG1 no hydrogen 3.034 N/A HIS 294.A NE2 HIS 29.A NE2 no hydrogen 3.061 N/A THR 296.A N ASP 293.A OD1 no hydrogen 3.182 N/A THR 296.A OG1 ASP 293.A OD1 no hydrogen 3.308 N/A ALA 297.A N ASP 293.A O no hydrogen 3.084 N/A THR 298.A N HIS 294.A O no hydrogen 2.949 N/A THR 298.A OG1 HIS 294.A O no hydrogen 2.686 N/A TYR 299.A N LEU 295.A O no hydrogen 2.931 N/A LEU 300.A N THR 296.A O no hydrogen 2.806 N/A LEU 301.A N ALA 297.A O no hydrogen 2.854 N/A LEU 302.A N THR 298.A O no hydrogen 2.964 N/A LEU 303.A N TYR 299.A O no hydrogen 2.901 N/A ALA 304.A N LEU 300.A O no hydrogen 2.966 N/A LYS 305.A N LEU 301.A O no hydrogen 3.150 N/A LYS 305.A NZ THR 32.A O no hydrogen 2.673 N/A LYS 305.A NZ GLU 34.A OE2 no hydrogen 2.640 N/A LYS 306.A N LEU 302.A O no hydrogen 3.129 N/A LYS 306.A NZ ASP 267.A OD2 no hydrogen 2.758 N/A ALA 307.A N LEU 303.A O no hydrogen 3.069 N/A ARG 308.A N ALA 304.A O no hydrogen 3.181 N/A ARG 308.A N LYS 305.A O no hydrogen 3.074 N/A ARG 308.A NH1 GLU 34.A OE1 no hydrogen 2.708 N/A ARG 308.A NH2 GLU 34.A OE1 no hydrogen 3.007 N/A ARG 308.A NH2 GLU 34.A OE2 no hydrogen 3.325 N/A GLY 309.A N LYS 306.A O no hydrogen 2.994 N/A LYS 310.A N LYS 305.A O no hydrogen 2.803 N/A ARG 313.A NH1 VAL 312.A O no hydrogen 3.134 N/A LEU 314.A N GLU 271.A OE2 no hydrogen 2.940 N/A ARG 315.A N LEU 31.A O no hydrogen 2.766 N/A