Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5m5b_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 1.A N GLU 5.A OE1 no hydrogen 3.325 N/A THR 2.A N GLU 5.A OE1 no hydrogen 2.951 N/A THR 2.A OG1 TYR 182.A O no hydrogen 2.692 N/A GLU 5.A N THR 2.A OG1 no hydrogen 3.127 N/A LYS 6.A N THR 2.A O no hydrogen 3.019 N/A TRP 7.A N LEU 3.A O no hydrogen 2.886 N/A TRP 7.A NE1 TYR 22.A OH no hydrogen 3.047 N/A LYS 8.A N GLY 4.A O no hydrogen 2.983 N/A LYS 8.A NZ SER 146.A O no hydrogen 2.691 N/A ALA 9.A N GLU 5.A O no hydrogen 3.050 N/A ARG 10.A N LYS 6.A O no hydrogen 2.995 N/A ARG 10.A NH2 ASP 240.A OD2 no hydrogen 2.885 N/A LEU 11.A N TRP 7.A O no hydrogen 2.814 N/A ASN 12.A N LYS 8.A O no hydrogen 3.038 N/A ASN 12.A ND2 SER 147.A O no hydrogen 2.849 N/A GLN 13.A N ARG 10.A O no hydrogen 3.024 N/A MET 14.A N LEU 11.A O no hydrogen 3.271 N/A GLU 18.A N SER 15.A OG no hydrogen 2.969 N/A PHE 19.A N SER 15.A O no hydrogen 2.849 N/A TYR 20.A N ALA 16.A O no hydrogen 2.953 N/A SER 21.A N LEU 17.A O no hydrogen 3.452 N/A SER 21.A OG GLU 18.A O no hydrogen 2.921 N/A TYR 22.A N GLU 18.A O no hydrogen 2.875 N/A TYR 22.A OH ASN 209.A O no hydrogen 3.426 N/A TYR 22.A OH LEU 235.A O no hydrogen 2.621 N/A LYS 23.A N PHE 19.A O no hydrogen 2.969 N/A LYS 24.A NZ GLU 29.A OE2 no hydrogen 3.396 N/A SER 25.A N TYR 22.A O no hydrogen 3.096 N/A GLY 26.A N ARG 244.A O no hydrogen 2.968 N/A ILE 27.A N LYS 24.A O no hydrogen 3.053 N/A THR 28.A N PRO 205.A O no hydrogen 3.107 N/A GLU 29.A N LYS 247.A O no hydrogen 2.920 N/A CYS 31.A N GLU 249.A O no hydrogen 2.908 N/A CYS 31.A SG GLU 249.A O no hydrogen 3.746 N/A ARG 32.A NH1 ALA 49.A O no hydrogen 2.795 N/A ARG 32.A NH1 ASP 251.A OD2 no hydrogen 2.669 N/A ARG 32.A NH2 ALA 49.A O no hydrogen 3.089 N/A ARG 36.A N ARG 32.A O no hydrogen 2.867 N/A ARG 37.A N GLU 33.A O no hydrogen 3.286 N/A ALA 38.A N GLU 34.A O no hydrogen 3.284 N/A LEU 39.A N ALA 35.A O no hydrogen 2.998 N/A LYS 40.A N ARG 36.A O no hydrogen 2.947 N/A ASP 41.A N ARG 37.A O no hydrogen 2.838 N/A GLY 42.A N LEU 39.A O no hydrogen 3.258 N/A VAL 43.A N ALA 38.A O no hydrogen 2.820 N/A ARG 52.A NH1.B VAL 30.A O no hydrogen 3.052 N/A GLY 53.A N SER 51.A OG no hydrogen 3.162 N/A SER 54.A OG GLY 81.A O no hydrogen 2.729 N/A LYS 56.A NZ GLU 213.A OE1 no hydrogen 2.785 N/A LYS 56.A NZ TYR 215.A OH no hydrogen 2.818 N/A LEU 57.A N GLY 53.A O no hydrogen 3.014 N/A ARG 58.A N SER 54.A O no hydrogen 2.843 N/A ARG 58.A NH2 GLU 250.A O no hydrogen 3.456 N/A TRP 59.A N ALA 55.A O no hydrogen 2.903 N/A LEU 60.A N LYS 56.A O no hydrogen 3.332 N/A VAL 61.A N LEU 57.A O no hydrogen 2.938 N/A GLU 62.A N ARG 58.A O no hydrogen 2.759 N/A ARG 63.A NH1 TRP 59.A O no hydrogen 3.148 N/A GLY 64.A N VAL 61.A O no hydrogen 3.016 N/A TYR 65.A N LEU 60.A O no hydrogen 3.053 N/A TYR 69.A N THR 137.A OG1 no hydrogen 3.022 N/A GLY 70.A N LYS 91.A O no hydrogen 2.881 N/A LYS 71.A N ASP 136.A OD2 no hydrogen 2.880 N/A LYS 71.A NZ GLU 133.A OE1.A no hydrogen 3.223 N/A LYS 71.A NZ PRO 134.A O no hydrogen 2.863 N/A VAL 72.A N GLU 94.A O no hydrogen 2.816 N/A ILE 73.A N THR 137.A O no hydrogen 2.874 N/A ASP 74.A N LYS 96.A O no hydrogen 2.791 N/A LEU 75.A N LEU 139.A O no hydrogen 2.820 N/A GLY 76.A N TYR 98.A O no hydrogen 2.802 N/A CYS 77.A N TYR 98.A O no hydrogen 2.935 N/A CYS 77.A SG GLY 78.A O no hydrogen 3.712 N/A GLY 78.A N THR 99.A OG1 no hydrogen 2.881 N/A ARG 79.A NH1 VAL 50.A O no hydrogen 3.239 N/A GLY 80.A N CYS 77.A O no hydrogen 3.073 N/A SER 83.A OG ASP 74.A OD2 no hydrogen 2.654 N/A TYR 84.A N GLY 80.A O no hydrogen 2.902 N/A TYR 84.A OH MET 109.A O no hydrogen 2.674 N/A TYR 85.A N GLY 81.A O no hydrogen 3.312 N/A ALA 86.A N TRP 82.A O no hydrogen 2.848 N/A ALA 87.A N SER 83.A O no hydrogen 3.068 N/A THR 88.A N TYR 85.A O no hydrogen 3.045 N/A THR 88.A OG1 TYR 85.A O no hydrogen 2.673 N/A ILE 89.A N ALA 86.A O no hydrogen 3.025 N/A VAL 92.A N ILE 89.A O no hydrogen 2.924 N/A GLN 93.A N GLY 70.A O no hydrogen 2.860 N/A GLU 94.A N GLY 70.A O no hydrogen 3.279 N/A VAL 95.A N ILE 118.A O no hydrogen 2.843 N/A LYS 96.A N VAL 72.A O no hydrogen 2.824 N/A LYS 96.A NZ TYR 98.A OH no hydrogen 3.232 N/A GLY 97.A N ARG 120.A O no hydrogen 2.864 N/A TYR 98.A N ASP 74.A O no hydrogen 2.905 N/A THR 99.A N LYS 122.A O no hydrogen 2.882 N/A GLY 102.A N GLU 107.A OE2 no hydrogen 2.775 N/A HIS 105.A N GLY 102.A O no hydrogen 3.037 N/A MET 109.A N ARG 79.A O no hydrogen 2.808 N/A VAL 111.A N TYR 84.A OH no hydrogen 3.475 N/A GLN 112.A N ALA 44.A O no hydrogen 2.882 N/A TYR 114.A N LEU 254.A O no hydrogen 3.121 N/A GLY 115.A N GLY 257.A O no hydrogen 2.976 N/A TRP 116.A N SER 113.A O no hydrogen 2.981 N/A ASN 117.A ND2 ARG 259.A O no hydrogen 2.951 N/A ILE 118.A N GLY 115.A O no hydrogen 3.082 N/A VAL 119.A N TRP 116.A O no hydrogen 3.073 N/A ARG 120.A N VAL 95.A O no hydrogen 2.902 N/A LYS 122.A N GLY 97.A O no hydrogen 2.812 N/A SER 123.A OG GLU 107.A OE1 no hydrogen 2.651 N/A GLY 124.A N LYS 100.A O no hydrogen 2.959 N/A VAL 125.A N THR 99.A O no hydrogen 2.995 N/A PHE 128.A N ASP 126.A OD1 no hydrogen 3.111 N/A HIS 129.A N ASP 126.A O no hydrogen 3.074 N/A HIS 129.A ND1 ASP 126.A OD2 no hydrogen 2.852 N/A MET 130.A N VAL 127.A O no hydrogen 3.289 N/A CYS 135.A SG THR 137.A O no hydrogen 3.585 N/A ASP 136.A N LYS 71.A O no hydrogen 2.954 N/A THR 137.A N LYS 71.A O no hydrogen 3.031 N/A THR 137.A OG1 TYR 69.A O no hydrogen 2.852 N/A LEU 138.A N ALA 173.A O no hydrogen 2.884 N/A LEU 139.A N ILE 73.A O no hydrogen 2.792 N/A CYS 140.A N CYS 175.A O no hydrogen 2.894 N/A CYS 140.A SG LEU 75.A O no hydrogen 3.999 N/A ASP 141.A N LEU 75.A O no hydrogen 3.257 N/A SER 146.A N GLU 152.A OE1 no hydrogen 2.850 N/A SER 148.A N SER 146.A OG no hydrogen 3.045 N/A SER 148.A OG GLU 150.A OE2 no hydrogen 3.222 N/A GLU 150.A N GLU 150.A OE2 no hydrogen 2.980 N/A VAL 151.A N SER 148.A OG no hydrogen 3.090 N/A GLU 152.A N SER 148.A O no hydrogen 3.073 N/A GLU 153.A N PRO 149.A O no hydrogen 3.001 N/A ALA 154.A N GLU 150.A O no hydrogen 2.951 N/A ARG 155.A N VAL 151.A O no hydrogen 2.946 N/A ARG 155.A NH1 GLU 144.A O no hydrogen 2.830 N/A ARG 155.A NH1 SER 145.A O no hydrogen 3.193 N/A THR 156.A N GLU 152.A O no hydrogen 2.889 N/A THR 156.A OG1 GLU 152.A O no hydrogen 2.702 N/A LEU 157.A N GLU 153.A O no hydrogen 2.846 N/A ARG 158.A N ALA 154.A O no hydrogen 3.108 N/A VAL 159.A N ARG 155.A O no hydrogen 3.081 N/A LEU 160.A N THR 156.A O no hydrogen 2.858 N/A SER 161.A N LEU 157.A O no hydrogen 2.977 N/A MET 162.A N ARG 158.A O no hydrogen 3.184 N/A VAL 163.A N VAL 159.A O no hydrogen 2.889 N/A GLY 164.A N LEU 160.A O no hydrogen 3.013 N/A ASP 165.A N MET 162.A O no hydrogen 3.160 N/A LEU 167.A N VAL 163.A O no hydrogen 2.912 N/A GLU 168.A N GLY 164.A O no hydrogen 3.092 N/A LYS 169.A N TRP 166.A O no hydrogen 3.084 N/A ARG 170.A N LEU 167.A O no hydrogen 2.920 N/A ALA 173.A N ASP 136.A O no hydrogen 3.094 N/A PHE 174.A N SER 218.A OG no hydrogen 2.845 N/A CYS 175.A N LEU 138.A O no hydrogen 2.926 N/A ILE 176.A N.A TRP 216.A O no hydrogen 2.798 N/A ILE 176.A N.B TRP 216.A O no hydrogen 2.808 N/A LYS 177.A N CYS 140.A O no hydrogen 2.809 N/A LYS 177.A NZ GLY 143.A O no hydrogen 3.042 N/A VAL 178.A N MET 214.A O no hydrogen 2.742 N/A CYS 180.A N THR 156.A OG1 no hydrogen 3.003 N/A TYR 182.A OH GLU 152.A OE2 no hydrogen 3.076 N/A THR 183.A OG1 GLU 153.A OE1 no hydrogen 2.677 N/A THR 185.A OG1.A GLU 153.A OE2 no hydrogen 2.676 N/A THR 185.A OG1.B GLU 153.A OE1 no hydrogen 3.252 N/A THR 185.A OG1.B GLU 153.A OE2 no hydrogen 2.720 N/A MET 186.A N THR 183.A OG1 no hydrogen 3.319 N/A MET 187.A N THR 183.A O no hydrogen 2.991 N/A GLU 188.A N SER 184.A O no hydrogen 3.224 N/A THR 189.A N THR 185.A O.A no hydrogen 2.886 N/A THR 189.A N THR 185.A O.B no hydrogen 3.042 N/A THR 189.A OG1 THR 185.A O.A no hydrogen 2.764 N/A THR 189.A OG1 THR 185.A O.B no hydrogen 2.715 N/A LEU 190.A N MET 186.A O no hydrogen 2.877 N/A GLU 191.A N MET 187.A O no hydrogen 2.956 N/A ARG 192.A N GLU 188.A O no hydrogen 3.050 N/A LEU 193.A N THR 189.A O no hydrogen 2.955 N/A GLN 194.A N LEU 190.A O no hydrogen 2.831 N/A ARG 195.A N GLU 191.A O no hydrogen 2.987 N/A ARG 195.A NE GLU 191.A OE1 no hydrogen 3.391 N/A ARG 195.A NH1 GLU 191.A OE1 no hydrogen 3.060 N/A ARG 196.A N ARG 192.A O no hydrogen 3.063 N/A TYR 197.A N LEU 193.A O no hydrogen 2.819 N/A TYR 197.A OH GLU 168.A OE1 no hydrogen 2.827 N/A GLY 198.A N GLN 194.A O no hydrogen 2.780 N/A GLY 200.A N VAL 217.A O no hydrogen 3.045 N/A VAL 202.A N TYR 215.A O no hydrogen 2.801 N/A ARG 203.A NH1 THR 211.A O no hydrogen 2.868 N/A ARG 203.A NH1 GLU 213.A O no hydrogen 2.816 N/A ARG 203.A NH2 ARG 208.A O no hydrogen 2.852 N/A ARG 203.A NH2 THR 211.A O no hydrogen 3.072 N/A SER 207.A N VAL 204.A O no hydrogen 3.001 N/A SER 207.A OG VAL 204.A O no hydrogen 3.344 N/A SER 207.A OG GLU 213.A OE1 no hydrogen 2.598 N/A ASN 209.A N LYS 23.A O no hydrogen 2.911 N/A ASN 209.A ND2 TYR 22.A O no hydrogen 2.806 N/A ASN 209.A ND2 SER 25.A O no hydrogen 2.761 N/A THR 211.A N ARG 208.A O no hydrogen 3.285 N/A HIS 212.A ND1 HIS 212.A O no hydrogen 2.695 N/A HIS 212.A NE2 SER 232.A OG no hydrogen 2.642 N/A GLU 213.A N THR 211.A OG1 no hydrogen 3.106 N/A MET 214.A N VAL 178.A O no hydrogen 3.005 N/A TYR 215.A N VAL 202.A O no hydrogen 2.814 N/A TYR 215.A OH ASP 141.A OD1 no hydrogen 2.766 N/A TRP 216.A N ILE 176.A O.A no hydrogen 2.774 N/A TRP 216.A N ILE 176.A O.B no hydrogen 2.779 N/A TRP 216.A NE1 GLY 198.A O no hydrogen 2.871 N/A VAL 217.A N GLY 200.A O no hydrogen 3.011 N/A SER 218.A N PHE 174.A O no hydrogen 3.024 N/A SER 218.A OG PHE 174.A O no hydrogen 3.340 N/A GLY 219.A N TYR 65.A O no hydrogen 2.760 N/A ALA 220.A N VAL 217.A O no hydrogen 3.395 N/A LYS 221.A NZ GLY 199.A O no hydrogen 2.682 N/A SER 222.A OG SER 227.A OG no hydrogen 2.721 N/A THR 224.A OG1 GLN 194.A OE1 no hydrogen 2.927 N/A LYS 226.A N ASN 223.A OD1 no hydrogen 2.908 N/A SER 227.A N ASN 223.A O no hydrogen 2.980 N/A SER 227.A OG SER 222.A OG no hydrogen 2.721 N/A SER 227.A OG ASN 223.A O no hydrogen 3.100 N/A VAL 228.A N THR 224.A O no hydrogen 2.986 N/A SER 229.A N ILE 225.A O no hydrogen 2.823 N/A SER 229.A OG ILE 225.A O no hydrogen 3.304 N/A THR 230.A N LYS 226.A O no hydrogen 2.846 N/A THR 230.A OG1 LYS 226.A O no hydrogen 2.819 N/A THR 231.A N SER 227.A O no hydrogen 3.314 N/A THR 231.A OG1 SER 227.A O no hydrogen 3.228 N/A SER 232.A N VAL 228.A O no hydrogen 2.888 N/A SER 232.A OG HIS 212.A NE2 no hydrogen 2.642 N/A SER 232.A OG VAL 228.A O no hydrogen 3.177 N/A GLN 233.A N SER 229.A O no hydrogen 2.882 N/A LEU 234.A N THR 230.A O no hydrogen 3.037 N/A LEU 235.A N THR 231.A O no hydrogen 3.031 N/A LEU 236.A N SER 232.A O no hydrogen 2.944 N/A GLY 237.A N GLN 233.A O no hydrogen 2.966 N/A ARG 238.A N LEU 234.A O no hydrogen 3.123 N/A ARG 238.A NH1 ASN 209.A OD1 no hydrogen 2.839 N/A MET 239.A N LEU 236.A O no hydrogen 3.028 N/A ASP 240.A N GLY 237.A O no hydrogen 3.436 N/A ARG 243.A NE SER 21.A O no hydrogen 2.894 N/A ARG 243.A NH1 ARG 244.A O no hydrogen 3.064 N/A ARG 244.A N SER 25.A OG no hydrogen 2.887 N/A LYS 247.A N ILE 27.A O no hydrogen 2.801 N/A GLU 249.A N GLU 29.A O no hydrogen 2.963 N/A VAL 252.A N.A ASP 251.A OD1 no hydrogen 2.900 N/A VAL 252.A N.B ASP 251.A OD1 no hydrogen 2.846 N/A LEU 254.A N GLY 47.A O no hydrogen 2.731 N/A GLY 255.A N ASN 253.A OD1 no hydrogen 3.288 N/A ARG 259.A N ASN 117.A OD1 no hydrogen 2.917 N/A ARG 259.A NH1 ALA 87.A O no hydrogen 2.813 N/A ARG 259.A NH1 ILE 89.A O no hydrogen 2.814 N/A ARG 259.A NH2 ARG 90.A O no hydrogen 2.756 N/A