Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5m8c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N GLU 8.A OE1 no hydrogen 2.801 N/A ARG 6.A NH1 ILE 180.A O no hydrogen 3.060 N/A GLU 8.A N THR 5.A OG1 no hydrogen 2.937 N/A PHE 9.A N THR 5.A O no hydrogen 3.021 N/A LEU 10.A N ARG 6.A O no hydrogen 2.793 N/A GLN 11.A N GLU 7.A O no hydrogen 3.310 N/A GLY 12.A N GLU 8.A O no hydrogen 3.086 N/A LEU 13.A N PHE 9.A O no hydrogen 2.895 N/A LEU 14.A N LEU 10.A O no hydrogen 3.015 N/A GLN 15.A N GLN 11.A O no hydrogen 3.013 N/A GLN 15.A NE2 GLN 15.A O no hydrogen 3.404 N/A GLN 15.A NE2 ASP 19.A OD1 no hydrogen 3.313 N/A SER 16.A N GLY 12.A O no hydrogen 2.917 N/A SER 17.A N LEU 13.A O no hydrogen 2.781 N/A SER 17.A OG ASP 197.A O no hydrogen 2.772 N/A ARG 18.A N LEU 14.A O no hydrogen 2.795 N/A ASP 19.A N GLN 15.A O no hydrogen 2.881 N/A PHE 20.A N SER 17.A O no hydrogen 3.190 N/A VAL 21.A N ARG 18.A O no hydrogen 3.424 N/A ARG 23.A N PHE 20.A O no hydrogen 2.994 N/A LYS 25.A NZ ASN 239.A O no hydrogen 3.495 N/A LEU 26.A N MET 61.A O no hydrogen 2.997 N/A LYS 35.A N THR 352.A O no hydrogen 3.059 N/A ASN 36.A N THR 352.A O no hydrogen 3.052 N/A GLU 38.A N ALA 350.A O no hydrogen 2.950 N/A LEU 40.A N ILE 348.A O no hydrogen 2.714 N/A GLN 43.A N PHE 346.A O no hydrogen 3.017 N/A TYR 45.A N ASP 344.A O no hydrogen 3.137 N/A TYR 45.A OH THR 342.A O no hydrogen 3.216 N/A SER 46.A N CYS 70.A O no hydrogen 2.823 N/A ARG 47.A NH1 THR 342.A O no hydrogen 3.051 N/A ILE 49.A N SER 46.A O no hydrogen 3.449 N/A LYS 50.A N ALA 104.A O no hydrogen 3.041 N/A THR 51.A OG1 CYS 68.A O no hydrogen 2.712 N/A PHE 52.A N ILE 106.A O no hydrogen 3.330 N/A TYR 54.A N TRP 66.A O no hydrogen 3.100 N/A TYR 54.A OH ASN 152.A OD1 no hydrogen 2.610 N/A LYS 55.A N TYR 149.A OH no hydrogen 3.202 N/A LYS 55.A NZ ASP 238.A OD1 no hydrogen 2.920 N/A LYS 55.A NZ ASP 284.A OD2 no hydrogen 2.685 N/A GLU 56.A N ASP 64.A O no hydrogen 3.033 N/A LEU 57.A N GLU 153.A OE2 no hydrogen 2.679 N/A ASN 58.A N TYR 62.A O no hydrogen 2.925 N/A ASN 58.A ND2 ASP 64.A OD2 no hydrogen 3.514 N/A SER 60.A N ASN 58.A OD1 no hydrogen 2.718 N/A MET 61.A N ASN 58.A O no hydrogen 2.855 N/A TYR 62.A N ASN 58.A OD1 no hydrogen 3.351 N/A ASP 64.A N GLU 56.A O no hydrogen 2.914 N/A LYS 65.A NZ ASP 284.A OD1 no hydrogen 2.726 N/A TRP 66.A N TYR 54.A O no hydrogen 2.878 N/A VAL 67.A N LEU 82.A O no hydrogen 2.975 N/A CYS 68.A SG MET 69.A O no hydrogen 3.932 N/A CYS 68.A SG THR 80.A O no hydrogen 4.023 N/A MET 69.A N THR 80.A O no hydrogen 3.066 N/A ARG 71.A N HIS 78.A O no hydrogen 2.833 N/A ARG 71.A NH1 GLN 43.A OE1 no hydrogen 2.751 N/A ARG 71.A NH1 ASN 44.A O no hydrogen 3.145 N/A CYS 72.A N SER 46.A OG no hydrogen 3.208 N/A CYS 72.A SG ALA 76.A O no hydrogen 3.893 N/A CYS 72.A SG GLY 100.A O no hydrogen 3.967 N/A CYS 72.A SG HIS 102.A ND1 no hydrogen 3.574 N/A GLU 73.A N ALA 76.A O no hydrogen 3.123 N/A ALA 76.A N GLU 73.A O no hydrogen 2.994 N/A LEU 77.A N THR 93.A O no hydrogen 2.799 N/A HIS 78.A N ARG 71.A O no hydrogen 2.765 N/A HIS 78.A ND1 THR 92.A OG1 no hydrogen 2.721 N/A PHE 79.A N ILE 91.A O no hydrogen 2.698 N/A THR 80.A N MET 69.A O no hydrogen 3.017 N/A THR 80.A OG1 THR 90.A OG1 no hydrogen 3.143 N/A GLN 81.A N THR 89.A O no hydrogen 2.984 N/A LEU 82.A N VAL 67.A O no hydrogen 3.242 N/A LYS 83.A N THR 87.A OG1 no hydrogen 3.080 N/A LYS 83.A NZ ASP 84.A OD2 no hydrogen 3.014 N/A SER 85.A N GLY 335.A O no hydrogen 3.098 N/A LYS 86.A N ASP 84.A OD1 no hydrogen 2.851 N/A THR 87.A N ASP 84.A O no hydrogen 3.444 N/A THR 87.A OG1 ASP 84.A O no hydrogen 3.357 N/A THR 87.A OG1 ASP 84.A OD1 no hydrogen 2.930 N/A THR 89.A N GLN 81.A O no hydrogen 3.092 N/A THR 90.A OG1 THR 80.A OG1 no hydrogen 3.143 N/A ILE 91.A N PHE 79.A O no hydrogen 2.851 N/A THR 92.A OG1 HIS 78.A ND1 no hydrogen 2.721 N/A THR 93.A N LEU 77.A O no hydrogen 2.990 N/A ASN 95.A N GLY 75.A O no hydrogen 2.907 N/A ASN 95.A ND2 GLU 101.A O no hydrogen 2.865 N/A ARG 97.A N ASN 95.A OD1 no hydrogen 3.077 N/A ARG 97.A NH2 GLN 122.A OE1 no hydrogen 3.260 N/A GLU 101.A N THR 98.A O no hydrogen 3.512 N/A HIS 102.A ND1 GLY 100.A O no hydrogen 3.126 N/A ALA 104.A N LEU 117.A O no hydrogen 2.826 N/A ILE 106.A N LYS 50.A O no hydrogen 2.847 N/A SER 107.A N LEU 115.A O no hydrogen 3.017 N/A SER 107.A OG MET 148.A O no hydrogen 2.694 N/A GLY 109.A N ARG 113.A O no hydrogen 2.825 N/A ARG 113.A N GLY 109.A O no hydrogen 3.410 N/A ARG 113.A NH1 PRO 110.A O no hydrogen 3.164 N/A LEU 114.A N LEU 126.A O no hydrogen 2.749 N/A LEU 115.A N SER 107.A O no hydrogen 2.609 N/A LEU 116.A N THR 124.A O no hydrogen 2.871 N/A LEU 117.A N ILE 105.A O no hydrogen 2.905 N/A TYR 118.A N GLN 122.A O no hydrogen 2.805 N/A TYR 118.A OH ASN 95.A OD1 no hydrogen 2.752 N/A ASN 121.A ND2 SER 141.A O no hydrogen 3.097 N/A ASN 121.A ND2 ASN 143.A O no hydrogen 2.940 N/A GLN 122.A N TYR 118.A O no hydrogen 3.226 N/A ILE 123.A N ILE 137.A O no hydrogen 2.772 N/A THR 124.A N LEU 116.A O no hydrogen 2.886 N/A THR 124.A OG1 GLU 136.A OE1 no hydrogen 2.854 N/A ILE 125.A N ARG 135.A O no hydrogen 2.977 N/A LEU 126.A N LEU 114.A O no hydrogen 2.928 N/A ASP 127.A N LYS 132.A O no hydrogen 3.011 N/A SER 128.A N ASN 112.A O no hydrogen 2.952 N/A LYS 129.A N ASP 127.A OD1 no hydrogen 2.672 N/A THR 130.A N ASP 127.A OD1 no hydrogen 3.163 N/A ASN 131.A N ASP 127.A O no hydrogen 2.820 N/A LEU 134.A N ILE 125.A O no hydrogen 2.728 N/A ARG 135.A N ILE 125.A O no hydrogen 3.349 N/A ARG 135.A NH1 SER 172.A O no hydrogen 3.073 N/A ARG 135.A NH1 TYR 173.A O no hydrogen 2.820 N/A ARG 135.A NH1 ASP 175.A O no hydrogen 3.109 N/A ILE 137.A N ILE 123.A O no hydrogen 2.769 N/A VAL 139.A N ASN 121.A O no hydrogen 3.040 N/A SER 141.A OG ASP 163.A OD2 no hydrogen 2.763 N/A ILE 145.A N ASN 121.A OD1 no hydrogen 2.990 N/A ILE 146.A N ALA 162.A O no hydrogen 2.814 N/A TYR 147.A N ALA 162.A O no hydrogen 3.183 N/A TYR 149.A N ILE 160.A O no hydrogen 2.890 N/A HIS 151.A NE2 LYS 196.A O no hydrogen 2.847 N/A ASN 152.A ND2 GLU 153.A OE2 no hydrogen 2.951 N/A GLU 153.A N HIS 151.A ND1 no hydrogen 3.063 N/A VAL 154.A N HIS 151.A ND1 no hydrogen 2.975 N/A ASN 155.A N SER 16.A OG no hydrogen 2.750 N/A TYR 158.A N ASN 155.A O no hydrogen 3.175 N/A PHE 159.A N GLN 171.A O no hydrogen 2.965 N/A ILE 160.A N TYR 149.A O no hydrogen 2.732 N/A TRP 161.A N GLY 169.A O no hydrogen 3.060 N/A ALA 162.A N TYR 147.A O no hydrogen 2.956 N/A ASP 163.A N THR 167.A O no hydrogen 3.097 N/A ASN 164.A N GLU 144.A O no hydrogen 2.815 N/A ARG 165.A N ASP 163.A OD1 no hydrogen 3.028 N/A ARG 165.A NH2 GLU 188.A OE1 no hydrogen 2.568 N/A GLY 166.A N ASP 163.A O no hydrogen 3.194 N/A THR 167.A N ASP 163.A OD1 no hydrogen 2.933 N/A THR 167.A OG1 ASP 163.A OD1 no hydrogen 3.502 N/A THR 167.A OG1 ASP 163.A OD2 no hydrogen 3.080 N/A ILE 168.A N HIS 182.A O no hydrogen 2.775 N/A GLY 169.A N TRP 161.A O no hydrogen 3.185 N/A PHE 170.A N TYR 179.A O no hydrogen 2.877 N/A GLN 171.A N PHE 159.A O no hydrogen 2.894 N/A SER 172.A N SER 177.A O no hydrogen 3.018 N/A SER 172.A OG ASP 175.A O no hydrogen 3.530 N/A TYR 173.A N GLU 157.A O no hydrogen 2.904 N/A GLU 174.A N SER 172.A OG no hydrogen 3.182 N/A ASP 175.A N SER 172.A OG no hydrogen 2.917 N/A TYR 179.A N PHE 170.A O no hydrogen 3.066 N/A TYR 179.A OH ALA 3.A O no hydrogen 2.804 N/A VAL 181.A N ILE 168.A O no hydrogen 2.846 N/A HIS 182.A N ILE 168.A O no hydrogen 3.366 N/A HIS 182.A NE2 ASN 214.A O no hydrogen 2.828 N/A TYR 189.A N ASN 164.A O no hydrogen 3.038 N/A TYR 189.A OH ASP 211.A OD2 no hydrogen 2.720 N/A TYR 189.A OH TYR 213.A OH no hydrogen 2.663 N/A SER 190.A N TYR 204.A O no hydrogen 2.802 N/A SER 190.A OG TYR 204.A O no hydrogen 3.502 N/A SER 191.A N TYR 204.A O no hydrogen 3.302 N/A SER 191.A OG TYR 204.A OH no hydrogen 3.343 N/A VAL 193.A N ALA 202.A O no hydrogen 2.987 N/A HIS 195.A N LEU 200.A O no hydrogen 2.945 N/A HIS 195.A NE2 GLY 240.A O no hydrogen 2.773 N/A LYS 196.A NZ PHE 20.A O no hydrogen 3.152 N/A LYS 196.A NZ ARG 23.A O no hydrogen 3.135 N/A LYS 196.A NZ TYR 63.A OH no hydrogen 3.132 N/A LYS 196.A NZ ASP 197.A OD1 no hydrogen 2.863 N/A ASP 197.A N HIS 195.A ND1 no hydrogen 3.097 N/A SER 198.A N HIS 195.A O no hydrogen 2.865 N/A SER 198.A OG SER 198.A O no hydrogen 2.570 N/A LEU 201.A N TYR 213.A O no hydrogen 2.999 N/A ALA 202.A N VAL 193.A O no hydrogen 2.876 N/A LEU 203.A N ASP 211.A O no hydrogen 2.851 N/A TYR 204.A N SER 191.A O no hydrogen 3.230 N/A SER 205.A N ILE 209.A O no hydrogen 3.198 N/A ASP 211.A N LEU 203.A O no hydrogen 2.943 N/A VAL 212.A N SER 223.A O no hydrogen 2.834 N/A TYR 213.A N LEU 201.A O no hydrogen 2.855 N/A TYR 213.A OH TYR 189.A OH no hydrogen 2.663 N/A LEU 215.A N LEU 199.A O no hydrogen 2.771 N/A SER 216.A N ASN 214.A OD1 no hydrogen 3.062 N/A SER 216.A OG ASN 214.A OD1 no hydrogen 3.052 N/A SER 217.A N ASN 214.A O no hydrogen 3.496 N/A SER 217.A OG SER 217.A O no hydrogen 2.529 N/A SER 217.A OG GLN 220.A OE1 no hydrogen 3.110 N/A ASP 219.A N VAL 181.A O no hydrogen 2.977 N/A GLN 220.A N SER 217.A O no hydrogen 3.280 N/A GLN 220.A NE2 ALA 221.A O no hydrogen 3.608 N/A SER 223.A N VAL 212.A O no hydrogen 3.026 N/A ARG 224.A NE ASP 211.A OD1 no hydrogen 2.946 N/A ARG 224.A NH1 ASP 186.A OD2 no hydrogen 3.060 N/A ARG 224.A NH2 ASP 186.A OD2 no hydrogen 2.937 N/A ARG 224.A NH2 ASP 211.A OD2 no hydrogen 3.150 N/A PHE 225.A N LEU 210.A O no hydrogen 2.880 N/A LYS 230.A NZ ASP 207.A OD1 no hydrogen 2.530 N/A ILE 231.A N PRO 206.A O no hydrogen 2.871 N/A LYS 232.A N GLU 246.A O no hydrogen 2.877 N/A LYS 232.A NZ GLU 246.A OE1 no hydrogen 3.336 N/A LYS 232.A NZ TYR 280.A O no hydrogen 2.838 N/A GLU 233.A N GLU 246.A O no hydrogen 3.202 N/A VAL 234.A N TYR 204.A OH no hydrogen 3.440 N/A LYS 235.A N VAL 244.A O no hydrogen 2.883 N/A LYS 235.A NZ GLU 233.A OE1 no hydrogen 3.075 N/A LYS 235.A NZ GLU 233.A OE2 no hydrogen 3.313 N/A LYS 235.A NZ ASP 281.A OD1 no hydrogen 2.857 N/A LYS 235.A NZ ASP 281.A OD2 no hydrogen 3.424 N/A LYS 235.A NZ ILE 282.A O no hydrogen 3.210 N/A ALA 237.A N TRP 242.A O no hydrogen 3.018 N/A ASP 238.A N ASP 284.A O no hydrogen 2.831 N/A GLY 240.A N ALA 237.A O no hydrogen 3.013 N/A TYR 241.A N ASN 239.A OD1 no hydrogen 2.773 N/A TRP 242.A N ASN 239.A OD1 no hydrogen 3.102 N/A MET 243.A N PHE 254.A O no hydrogen 3.010 N/A VAL 244.A N LYS 235.A O no hydrogen 2.760 N/A VAL 245.A N VAL 252.A O no hydrogen 2.627 N/A GLU 246.A N GLU 233.A O no hydrogen 2.874 N/A CYS 247.A N THR 250.A O no hydrogen 2.817 N/A CYS 247.A SG VAL 245.A O no hydrogen 3.947 N/A ASP 248.A N LYS 230.A O no hydrogen 3.094 N/A VAL 251.A N TYR 268.A O no hydrogen 2.828 N/A VAL 252.A N VAL 245.A O no hydrogen 3.051 N/A PHE 254.A N MET 243.A O no hydrogen 2.915 N/A ASP 255.A N THR 262.A O no hydrogen 2.894 N/A LEU 256.A N TYR 241.A O no hydrogen 2.809 N/A ARG 257.A N ASP 255.A OD1 no hydrogen 2.933 N/A ARG 257.A NE ASP 255.A OD1 no hydrogen 2.995 N/A ARG 257.A NH2 ASP 255.A OD2 no hydrogen 2.683 N/A LYS 258.A N ASP 255.A O no hydrogen 3.210 N/A THR 262.A N ASP 259.A O no hydrogen 2.914 N/A THR 262.A OG1 ASP 259.A O no hydrogen 2.749 N/A ALA 264.A N CYS 253.A O no hydrogen 2.840 N/A TYR 268.A N VAL 251.A O no hydrogen 3.041 N/A ILE 270.A N GLN 249.A O no hydrogen 2.884 N/A THR 275.A OG1 THR 275.A O no hydrogen 2.354 N/A VAL 278.A N GLY 276.A O no hydrogen 3.012 N/A THR 279.A N TYR 292.A O no hydrogen 3.043 N/A TYR 280.A OH CYS 247.A O no hydrogen 2.685 N/A ASP 281.A N ILE 290.A O no hydrogen 3.032 N/A ILE 282.A N GLU 246.A OE2 no hydrogen 3.044 N/A ASP 283.A N ASN 288.A O no hydrogen 3.001 N/A SER 285.A OG ASP 283.A OD1 no hydrogen 2.797 N/A SER 285.A OG ASP 283.A OD2 no hydrogen 3.277 N/A GLY 286.A N ASP 283.A O no hydrogen 3.008 N/A LYS 287.A N SER 285.A OG no hydrogen 3.098 N/A ASN 288.A ND2 ASP 283.A OD2 no hydrogen 2.953 N/A MET 289.A N TYR 302.A O no hydrogen 3.019 N/A ILE 290.A N ASP 281.A O no hydrogen 3.087 N/A ALA 291.A N THR 300.A O no hydrogen 2.803 N/A TYR 292.A N THR 279.A O no hydrogen 2.733 N/A SER 293.A N SER 298.A O no hydrogen 3.115 N/A SER 293.A OG SER 296.A OG no hydrogen 3.323 N/A ASN 294.A ND2 THR 277.A O no hydrogen 3.673 N/A ASN 294.A ND2 PHE 324.A O no hydrogen 2.721 N/A ASN 297.A ND2 TYR 292.A OH no hydrogen 3.256 N/A SER 298.A OG LEU 319.A O no hydrogen 2.848 N/A LEU 299.A N LEU 319.A O no hydrogen 2.723 N/A THR 300.A N ALA 291.A O no hydrogen 2.758 N/A TYR 302.A N MET 289.A O no hydrogen 2.887 N/A LYS 303.A N THR 312.A O no hydrogen 3.011 N/A LYS 303.A NZ PHE 304.A O no hydrogen 3.046 N/A PHE 304.A N LYS 287.A O no hydrogen 2.941 N/A ASP 305.A N ASN 310.A O no hydrogen 3.184 N/A LYS 307.A N ASP 305.A OD1 no hydrogen 2.787 N/A THR 308.A N ASP 305.A OD1 no hydrogen 3.420 N/A THR 308.A OG1 ASP 305.A O no hydrogen 3.487 N/A THR 308.A OG1 ASN 310.A OD1 no hydrogen 2.705 N/A LYS 309.A N ASP 305.A O no hydrogen 2.645 N/A TRP 311.A NE1 TYR 265.A OH no hydrogen 3.163 N/A THR 312.A N LYS 303.A O no hydrogen 3.117 N/A ASP 314.A N ILE 301.A O no hydrogen 2.699 N/A GLU 315.A N GLU 315.A OE1 no hydrogen 2.663 N/A GLU 316.A N ASP 314.A OD1 no hydrogen 3.225 N/A SER 317.A N ASP 314.A O no hydrogen 3.374 N/A SER 317.A OG LEU 34.A O no hydrogen 2.797 N/A CYS 320.A SG SER 298.A OG no hydrogen 3.780 N/A LEU 321.A N ASN 297.A O no hydrogen 2.837 N/A PHE 324.A N ASN 294.A OD1 no hydrogen 3.012 N/A THR 325.A N LYS 341.A O no hydrogen 2.876 N/A THR 325.A OG1 ASN 343.A OD1 no hydrogen 3.233 N/A ASP 326.A N LYS 341.A O no hydrogen 3.304 N/A ASP 328.A N ILE 339.A O no hydrogen 3.107 N/A VAL 329.A N ASP 281.A OD2 no hydrogen 3.102 N/A VAL 330.A N ALA 337.A O no hydrogen 2.941 N/A CYS 331.A SG ASP 283.A OD2 no hydrogen 3.801 N/A GLY 332.A N LYS 83.A O no hydrogen 2.940 N/A GLY 334.A N ASP 84.A OD2 no hydrogen 3.099 N/A GLY 335.A N GLY 332.A O no hydrogen 3.182 N/A ALA 337.A N VAL 330.A O no hydrogen 2.944 N/A ALA 338.A N VAL 349.A O no hydrogen 2.987 N/A ILE 339.A N ASP 328.A O no hydrogen 2.753 N/A LEU 340.A N ASN 347.A O no hydrogen 2.828 N/A LYS 341.A N ASP 326.A O no hydrogen 3.074 N/A LYS 341.A NZ ASP 328.A OD2 no hydrogen 2.712 N/A THR 342.A N SER 345.A O no hydrogen 2.818 N/A THR 342.A OG1 SER 345.A O no hydrogen 3.566 N/A THR 342.A OG1 SER 345.A OG no hydrogen 3.378 N/A ASP 344.A N THR 342.A OG1 no hydrogen 3.049 N/A SER 345.A N THR 342.A OG1 no hydrogen 3.187 N/A SER 345.A OG THR 342.A OG1 no hydrogen 3.378 N/A PHE 346.A N GLN 43.A O no hydrogen 2.857 N/A ASN 347.A N LEU 340.A O no hydrogen 2.711 N/A ILE 348.A N GLN 41.A O no hydrogen 3.148 N/A VAL 349.A N ALA 338.A O no hydrogen 2.925 N/A ALA 350.A N GLU 38.A O no hydrogen 2.842 N/A LEU 351.A N ILE 336.A O no hydrogen 2.938 N/A THR 352.A N ASN 36.A O no hydrogen 3.065 N/A