Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5mdx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 8.A OG1 MET 5.A O no hydrogen 2.324 N/A LEU 9.A N MET 5.A O no hydrogen 2.860 N/A LEU 10.A N ILE 6.A O no hydrogen 2.933 N/A THR 11.A N PRO 7.A O no hydrogen 2.937 N/A THR 11.A OG1 PRO 7.A O no hydrogen 3.107 N/A ALA 12.A N THR 8.A O no hydrogen 2.915 N/A THR 13.A N LEU 9.A O no hydrogen 2.875 N/A THR 13.A OG1 LEU 9.A O no hydrogen 2.283 N/A SER 14.A N LEU 10.A O no hydrogen 2.880 N/A SER 14.A OG LEU 10.A O no hydrogen 2.998 N/A SER 14.A OG THR 11.A O no hydrogen 2.502 N/A VAL 15.A N THR 11.A O no hydrogen 2.929 N/A PHE 16.A N ALA 12.A O no hydrogen 2.895 N/A ILE 17.A N THR 13.A O no hydrogen 2.901 N/A ILE 18.A N SER 14.A O no hydrogen 2.941 N/A ALA 19.A N VAL 15.A O no hydrogen 2.897 N/A ILE 21.A N ILE 17.A O no hydrogen 2.970 N/A ILE 21.A N ILE 18.A O no hydrogen 3.283 N/A ALA 22.A N ILE 18.A O no hydrogen 2.915 N/A VAL 26.A N VAL 35.A O no hydrogen 2.489 N/A ASP 29.A N ASP 27.A OD1 no hydrogen 3.043 N/A GLU 33.A N ASP 27.A OD2 no hydrogen 2.680 N/A VAL 35.A N VAL 26.A O no hydrogen 2.898 N/A SER 38.A OG ALA 23.A O no hydrogen 2.820 N/A LEU 40.A N ILE 21.A O no hydrogen 3.315 N/A TYR 41.A N SER 38.A O no hydrogen 3.265 N/A GLY 42.A N LEU 39.A O no hydrogen 2.953 N/A ASN 43.A N LEU 39.A O no hydrogen 3.083 N/A ASN 43.A ND2 SER 38.A O no hydrogen 2.547 N/A ASN 44.A N SER 47.A OG no hydrogen 3.008 N/A SER 47.A N ASN 44.A OD1 no hydrogen 2.537 N/A SER 47.A OG ASN 43.A OD1 no hydrogen 2.978 N/A SER 47.A OG ASN 44.A OD1 no hydrogen 2.656 N/A ALA 49.A N GLY 37.A O no hydrogen 2.833 N/A ILE 50.A N LEU 142.A O no hydrogen 2.883 N/A THR 53.A OG1 ASN 76.A O no hydrogen 2.615 N/A SER 54.A N THR 53.A OG1 no hydrogen 2.681 N/A ALA 56.A N SER 54.A OG no hydrogen 3.211 N/A HIS 60.A N ILE 57.A O no hydrogen 3.315 N/A ALA 67.A N ILE 64.A O no hydrogen 3.013 N/A GLU 72.A N SER 69.A O no hydrogen 3.088 N/A GLU 72.A N SER 69.A OG no hydrogen 3.238 N/A TRP 73.A N SER 69.A O no hydrogen 2.981 N/A TRP 73.A NE1 TYR 62.A O no hydrogen 3.055 N/A LEU 74.A N VAL 70.A O no hydrogen 2.895 N/A ASN 76.A N TRP 73.A O no hydrogen 3.402 N/A ASN 76.A ND2 TYR 62.A OH no hydrogen 3.261 N/A GLY 78.A N TRP 73.A O no hydrogen 3.185 N/A TYR 80.A OH MET 140.A O no hydrogen 2.292 N/A GLU 81.A N GLY 77.A O no hydrogen 3.018 N/A LEU 82.A N GLY 78.A O no hydrogen 2.993 N/A ILE 83.A N PRO 79.A O no hydrogen 2.879 N/A VAL 84.A N TYR 80.A O no hydrogen 2.914 N/A LEU 85.A N GLU 81.A O no hydrogen 3.020 N/A HIS 86.A N LEU 82.A O no hydrogen 2.981 N/A HIS 86.A ND1 LEU 82.A O no hydrogen 2.691 N/A PHE 87.A N ILE 83.A O no hydrogen 2.843 N/A LEU 88.A N VAL 84.A O no hydrogen 2.951 N/A LEU 89.A N LEU 85.A O no hydrogen 3.007 N/A GLY 90.A N HIS 86.A O no hydrogen 2.931 N/A VAL 91.A N PHE 87.A O no hydrogen 2.933 N/A ALA 92.A N LEU 88.A O no hydrogen 3.035 N/A CYS 93.A N LEU 89.A O no hydrogen 2.960 N/A CYS 93.A SG LEU 89.A O no hydrogen 3.234 N/A TYR 94.A N GLY 90.A O no hydrogen 2.913 N/A MET 95.A N VAL 91.A O no hydrogen 3.035 N/A GLY 96.A N ALA 92.A O no hydrogen 3.032 N/A ARG 97.A N CYS 93.A O no hydrogen 2.864 N/A GLU 98.A N TYR 94.A O no hydrogen 3.021 N/A TRP 99.A N MET 95.A O no hydrogen 3.074 N/A GLU 100.A N GLY 96.A O no hydrogen 2.947 N/A LEU 101.A N ARG 97.A O no hydrogen 2.933 N/A SER 102.A N GLU 98.A O no hydrogen 2.973 N/A SER 102.A OG GLU 98.A O no hydrogen 3.098 N/A SER 102.A OG TRP 99.A O no hydrogen 2.422 N/A PHE 103.A N TRP 99.A O no hydrogen 2.941 N/A PHE 103.A N GLU 100.A O no hydrogen 3.050 N/A ARG 104.A N GLU 100.A O no hydrogen 2.923 N/A LEU 105.A N LEU 101.A O no hydrogen 2.923 N/A MET 107.A N SER 102.A O no hydrogen 3.050 N/A ALA 114.A N TRP 110.A O no hydrogen 2.960 N/A TYR 115.A N ILE 111.A O no hydrogen 2.940 N/A SER 116.A N VAL 113.A O no hydrogen 3.275 N/A SER 116.A OG VAL 113.A O no hydrogen 2.615 N/A ALA 120.A N SER 116.A O no hydrogen 3.221 N/A ALA 121.A N ALA 117.A O no hydrogen 2.980 N/A ALA 122.A N PRO 118.A O no hydrogen 2.964 N/A THR 123.A N VAL 119.A O no hydrogen 2.939 N/A THR 123.A OG1 VAL 119.A O no hydrogen 3.306 N/A THR 123.A OG1 ALA 120.A O no hydrogen 2.556 N/A ALA 124.A N ALA 120.A O no hydrogen 2.951 N/A VAL 125.A N ALA 121.A O no hydrogen 2.944 N/A PHE 126.A N ALA 122.A O no hydrogen 2.905 N/A LEU 127.A N THR 123.A O no hydrogen 2.885 N/A ILE 128.A N THR 123.A O no hydrogen 2.984 N/A TYR 129.A N ALA 124.A O no hydrogen 3.064 N/A TYR 129.A OH HIS 158.A NE2 no hydrogen 3.057 N/A ILE 131.A N LEU 127.A O no hydrogen 2.944 N/A GLY 132.A N ILE 128.A O no hydrogen 2.843 N/A GLN 133.A N TYR 129.A O no hydrogen 2.931 N/A GLY 134.A N ILE 131.A O no hydrogen 3.119 N/A SER 135.A N PRO 130.A O no hydrogen 2.928 N/A SER 135.A OG SER 137.A OG no hydrogen 2.353 N/A PHE 136.A N GLY 58.A O no hydrogen 2.954 N/A SER 137.A N SER 135.A OG no hydrogen 3.248 N/A SER 137.A OG SER 135.A OG no hydrogen 2.353 N/A ASP 138.A N SER 135.A O no hydrogen 2.978 N/A GLY 139.A N PHE 136.A O no hydrogen 2.924 N/A LEU 142.A N ILE 50.A O no hydrogen 3.117 N/A SER 145.A N ILE 46.A O no hydrogen 3.411 N/A SER 145.A OG ILE 46.A O no hydrogen 3.066 N/A THR 147.A OG1 PRO 141.A O no hydrogen 3.526 N/A THR 147.A OG1 GLY 143.A O no hydrogen 2.788 N/A PHE 148.A N ILE 144.A O no hydrogen 2.964 N/A ASN 149.A N SER 145.A O no hydrogen 2.907 N/A PHE 150.A N GLY 146.A O no hydrogen 2.900 N/A MET 151.A N THR 147.A O no hydrogen 3.003 N/A ILE 152.A N PHE 148.A O no hydrogen 2.930 N/A VAL 153.A N ASN 149.A O no hydrogen 2.926 N/A PHE 154.A N PHE 150.A O no hydrogen 2.956 N/A GLN 155.A N MET 151.A O no hydrogen 2.933 N/A GLN 155.A NE2 ASN 159.A OD1 no hydrogen 3.070 N/A ALA 156.A N ILE 152.A O no hydrogen 2.953 N/A GLU 157.A N VAL 153.A O no hydrogen 2.946 N/A ASN 159.A N GLN 155.A O no hydrogen 2.841 N/A MET 162.A N ASN 159.A O no hydrogen 3.310 N/A MET 162.A N ASN 159.A OD1 no hydrogen 3.326 N/A MET 167.A N HIS 163.A O no hydrogen 3.046 N/A LEU 168.A N PRO 164.A O no hydrogen 2.839 N/A GLY 169.A N PHE 165.A O no hydrogen 2.967 N/A VAL 170.A N HIS 166.A O no hydrogen 2.965 N/A ALA 171.A N MET 167.A O no hydrogen 3.016 N/A GLY 172.A N LEU 168.A O no hydrogen 2.897 N/A GLY 172.A N GLY 169.A O no hydrogen 3.033 N/A VAL 173.A N GLY 169.A O no hydrogen 2.921 N/A PHE 174.A N VAL 170.A O no hydrogen 2.929 N/A GLY 175.A N ALA 171.A O no hydrogen 2.893 N/A GLY 176.A N GLY 172.A O no hydrogen 2.897 N/A SER 177.A N VAL 173.A O no hydrogen 2.945 N/A SER 177.A OG VAL 173.A O no hydrogen 2.705 N/A LEU 178.A N PHE 174.A O no hydrogen 2.903 N/A PHE 179.A N GLY 175.A O no hydrogen 2.857 N/A SER 180.A N GLY 176.A O no hydrogen 2.889 N/A SER 180.A OG GLY 176.A O no hydrogen 2.650 N/A ALA 181.A N SER 177.A O no hydrogen 3.054 N/A MET 182.A N LEU 178.A O no hydrogen 2.843 N/A HIS 183.A N PHE 179.A O no hydrogen 2.879 N/A GLY 184.A N SER 180.A O no hydrogen 2.907 N/A SER 185.A N ALA 181.A O no hydrogen 2.894 N/A SER 185.A OG ALA 181.A O no hydrogen 2.975 N/A SER 185.A OG MET 182.A O no hydrogen 2.477 N/A LEU 186.A N MET 182.A O no hydrogen 2.927 N/A VAL 187.A N HIS 183.A O no hydrogen 2.953 N/A THR 188.A N GLY 184.A O no hydrogen 2.893 N/A THR 188.A OG1 GLY 184.A O no hydrogen 2.308 N/A SER 189.A N LEU 186.A O no hydrogen 3.283 N/A SER 189.A OG SER 185.A O no hydrogen 2.319 N/A SER 190.A OG SER 190.A O no hydrogen 2.543 N/A SER 190.A OG ASN 215.A O no hydrogen 3.492 N/A THR 195.A OG1 SER 200.A O no hydrogen 3.460 N/A ASN 198.A N THR 196.A OG1 no hydrogen 3.345 N/A ASN 202.A N SER 200.A OG no hydrogen 3.293 N/A GLU 203.A N SER 200.A OG no hydrogen 3.414 N/A TYR 205.A OH GLU 211.A O no hydrogen 3.280 N/A ASN 215.A N SER 190.A OG no hydrogen 2.775 N/A VAL 217.A N ASN 215.A OD1 no hydrogen 3.249 N/A ALA 219.A N ASN 215.A O no hydrogen 2.928 N/A HIS 220.A N ILE 216.A O no hydrogen 2.972 N/A GLY 221.A N VAL 217.A O no hydrogen 2.855 N/A TYR 222.A N ALA 218.A O no hydrogen 2.908 N/A PHE 223.A N ALA 219.A O no hydrogen 3.047 N/A GLY 224.A N HIS 220.A O no hydrogen 2.844 N/A ARG 225.A N TYR 222.A O no hydrogen 3.375 N/A LEU 226.A N TYR 222.A O no hydrogen 2.899 N/A ILE 227.A N PHE 223.A O no hydrogen 3.002 N/A ARG 237.A N ASN 235.A OD1 no hydrogen 2.789 N/A LEU 239.A N ASN 235.A O no hydrogen 2.851 N/A HIS 240.A N SER 236.A O no hydrogen 2.906 N/A HIS 240.A ND1 SER 236.A O no hydrogen 2.728 N/A PHE 241.A N ARG 237.A O no hydrogen 2.877 N/A PHE 242.A N SER 238.A O no hydrogen 2.876 N/A LEU 243.A N LEU 239.A O no hydrogen 2.955 N/A ALA 244.A N HIS 240.A O no hydrogen 2.995 N/A TRP 246.A N PHE 242.A O no hydrogen 3.052 N/A TRP 246.A NE1 ALA 171.A O no hydrogen 2.938 N/A GLY 250.A N TRP 246.A O no hydrogen 3.178 N/A ILE 251.A N PRO 247.A O no hydrogen 2.865 N/A TRP 252.A N VAL 248.A O no hydrogen 2.897 N/A PHE 253.A N VAL 249.A O no hydrogen 3.038 N/A THR 254.A N GLY 250.A O no hydrogen 3.048 N/A THR 254.A OG1 ILE 251.A O no hydrogen 2.277 N/A ALA 255.A N ILE 251.A O no hydrogen 2.984 N/A LEU 256.A N TRP 252.A O no hydrogen 3.026 N/A GLY 257.A N PHE 253.A O no hydrogen 2.855 N/A ILE 258.A N THR 254.A O no hydrogen 2.937 N/A SER 259.A N ALA 255.A O no hydrogen 3.010 N/A SER 259.A OG ALA 255.A O no hydrogen 2.819 N/A THR 260.A N LEU 256.A O no hydrogen 2.914 N/A THR 260.A OG1 LEU 256.A O no hydrogen 3.061 N/A THR 260.A OG1 GLY 257.A O no hydrogen 2.589 N/A MET 261.A N GLY 257.A O no hydrogen 2.888 N/A ALA 262.A N SER 259.A O no hydrogen 3.301 N/A PHE 263.A N THR 260.A O no hydrogen 3.411 N/A ASN 271.A N ASN 269.A OD1 no hydrogen 3.203 N/A GLN 272.A N ASP 287.A OD1 no hydrogen 3.132 N/A SER 273.A OG PHE 270.A O no hydrogen 2.488 N/A ASP 276.A N ARG 280.A O no hydrogen 2.914 N/A ARG 280.A NH1 ASP 276.A OD2 no hydrogen 2.990 N/A ILE 282.A N VAL 274.A O no hydrogen 2.531 N/A THR 284.A N ASP 287.A OD2 no hydrogen 2.941 N/A ASP 287.A N THR 284.A OG1 no hydrogen 3.293 N/A ILE 288.A N THR 284.A O no hydrogen 3.000 N/A ILE 289.A N TRP 285.A O no hydrogen 2.984 N/A ASN 290.A N ALA 286.A O no hydrogen 2.930 N/A ARG 291.A N ASP 287.A O no hydrogen 2.958 N/A ALA 292.A N ILE 288.A O no hydrogen 3.018 N/A ASN 293.A N ILE 289.A O no hydrogen 2.896 N/A LEU 294.A N ASN 290.A O no hydrogen 2.914 N/A GLY 295.A N ARG 291.A O no hydrogen 3.007 N/A MET 296.A N ALA 292.A O no hydrogen 2.948 N/A GLU 297.A N ASN 293.A O no hydrogen 2.908 N/A VAL 298.A N LEU 294.A O no hydrogen 2.951 N/A MET 299.A N MET 296.A O no hydrogen 3.293 N/A HIS 300.A N MET 296.A O no hydrogen 2.891 N/A HIS 300.A ND1 MET 296.A O no hydrogen 2.717 N/A HIS 300.A NE2 GLU 157.A OE2 no hydrogen 2.688 N/A ALA 304.A N GLU 301.A O no hydrogen 3.009 N/A HIS 305.A N GLU 301.A O no hydrogen 2.808 N/A HIS 305.A ND1 GLU 301.A O no hydrogen 2.946 N/A ASN 306.A ND2 ASN 303.A O no hydrogen 3.192 N/A