Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5mhq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 2.A N GLU 66.A OE2 no hydrogen 3.167 N/A MET 4.A N PRO 1.A O no hydrogen 3.136 N/A GLU 5.A N GLU 2.A O no hydrogen 2.922 N/A ASN 6.A N PHE 3.A O no hydrogen 3.066 N/A PHE 7.A N MET 4.A O no hydrogen 3.075 N/A GLN 8.A N ARG 25.A O no hydrogen 2.785 N/A VAL 10.A N LYS 23.A O no hydrogen 2.883 N/A GLU 11.A N LYS 23.A O no hydrogen 3.483 N/A LYS 12.A NZ GLU 15.A OE2 no hydrogen 2.941 N/A ILE 13.A N VAL 21.A O no hydrogen 2.825 N/A GLY 14.A N VAL 21.A O no hydrogen 3.247 N/A GLY 16.A N GLY 19.A O no hydrogen 2.872 N/A TYR 18.A OH GLY 146.A O no hydrogen 2.509 N/A VAL 21.A N GLY 14.A O no hydrogen 2.953 N/A TYR 22.A N LEU 35.A O no hydrogen 2.853 N/A LYS 23.A N GLU 11.A O no hydrogen 2.920 N/A ALA 24.A N VAL 33.A O no hydrogen 2.886 N/A ARG 25.A N GLN 8.A O no hydrogen 2.953 N/A ARG 25.A NH2 GLN 8.A OE1 no hydrogen 3.494 N/A ASN 26.A N GLU 31.A O no hydrogen 2.921 N/A LYS 27.A N ASN 6.A O no hydrogen 2.653 N/A LYS 27.A NZ GLU 5.A O no hydrogen 3.168 N/A LYS 27.A NZ GLU 5.A OE1 no hydrogen 3.229 N/A LEU 28.A N ASN 26.A OD1 no hydrogen 3.059 N/A THR 29.A N ASN 26.A OD1 no hydrogen 2.955 N/A GLY 30.A N ASN 26.A O no hydrogen 2.678 N/A GLU 31.A N THR 29.A OG1 no hydrogen 3.269 N/A VAL 33.A N ALA 24.A O no hydrogen 2.902 N/A ALA 34.A N PHE 73.A O no hydrogen 2.853 N/A LEU 35.A N TYR 22.A O no hydrogen 2.768 N/A ILE 37.A N LEU 69.A O no hydrogen 2.783 N/A LEU 39.A N ASN 67.A O no hydrogen 2.796 N/A GLU 44.A N THR 40.A O no hydrogen 3.152 N/A ILE 45.A N ALA 41.A O no hydrogen 2.927 N/A SER 46.A N ILE 42.A O no hydrogen 2.870 N/A SER 46.A OG ILE 42.A O no hydrogen 2.728 N/A LEU 47.A N ARG 43.A O no hydrogen 3.116 N/A LEU 48.A N ILE 45.A O no hydrogen 2.983 N/A LYS 49.A N SER 46.A O no hydrogen 3.104 N/A GLU 50.A N LEU 47.A O no hydrogen 3.215 N/A LEU 51.A N LEU 48.A O no hydrogen 3.029 N/A ASN 52.A ND2 LYS 49.A O no hydrogen 3.306 N/A ASN 55.A N HIS 53.A ND1 no hydrogen 2.968 N/A ASN 55.A ND2 GLN 103.A OE1 no hydrogen 3.151 N/A ASN 55.A ND2 ILE 134.A O no hydrogen 2.927 N/A ILE 56.A N HIS 53.A O no hydrogen 3.025 N/A VAL 57.A N LEU 136.A O no hydrogen 2.971 N/A LYS 58.A N GLU 74.A OE2 no hydrogen 2.850 N/A LEU 60.A N VAL 72.A O no hydrogen 2.750 N/A ASP 61.A N VAL 72.A O no hydrogen 3.294 N/A ILE 63.A N TYR 70.A O no hydrogen 2.880 N/A THR 65.A N LYS 68.A O no hydrogen 3.022 N/A LYS 68.A N THR 65.A O no hydrogen 3.035 N/A LEU 69.A N ILE 37.A O no hydrogen 2.893 N/A TYR 70.A N ILE 63.A O no hydrogen 2.866 N/A VAL 72.A N ASP 61.A O no hydrogen 2.944 N/A PHE 73.A N ALA 34.A O no hydrogen 2.821 N/A GLU 74.A N LYS 58.A O no hydrogen 2.891 N/A GLN 78.A N ILE 128.A O no hydrogen 3.356 N/A ASP 79.A N GLN 78.A OE1 no hydrogen 3.008 N/A LEU 80.A N LEU 126.A O no hydrogen 2.809 N/A LYS 81.A NZ ASP 85.A OD1 no hydrogen 3.548 N/A LYS 81.A NZ ASP 85.A OD2 no hydrogen 2.569 N/A LYS 82.A N ASP 79.A OD1 no hydrogen 2.872 N/A LYS 82.A NZ ASP 79.A OD2 no hydrogen 2.971 N/A PHE 83.A N ASP 79.A O no hydrogen 3.039 N/A MET 84.A N LEU 80.A O no hydrogen 2.736 N/A ASP 85.A N LYS 81.A O no hydrogen 2.956 N/A ALA 86.A N LYS 82.A O no hydrogen 2.888 N/A SER 87.A N MET 84.A O no hydrogen 3.189 N/A SER 87.A OG PHE 83.A O no hydrogen 2.795 N/A ALA 88.A N ASP 85.A O no hydrogen 3.143 N/A THR 90.A N SER 87.A O no hydrogen 3.293 N/A THR 90.A OG1 SER 87.A O no hydrogen 3.449 N/A THR 90.A OG1 GLY 91.A O no hydrogen 3.507 N/A GLY 91.A N SER 87.A O no hydrogen 2.613 N/A LEU 96.A N PRO 93.A O no hydrogen 2.928 N/A ILE 97.A N PRO 93.A O no hydrogen 2.962 N/A LYS 98.A N LEU 94.A O no hydrogen 2.886 N/A LYS 98.A NZ PHE 278.A O no hydrogen 2.776 N/A LYS 98.A NZ ASP 281.A OD1 no hydrogen 2.625 N/A SER 99.A N PRO 95.A O no hydrogen 3.008 N/A SER 99.A OG THR 283.A O no hydrogen 3.384 N/A TYR 100.A N LEU 96.A O no hydrogen 2.878 N/A LEU 101.A N ILE 97.A O no hydrogen 2.847 N/A PHE 102.A N LYS 98.A O no hydrogen 2.890 N/A GLN 103.A N SER 99.A O no hydrogen 2.944 N/A GLN 103.A NE2 SER 99.A O no hydrogen 3.399 N/A GLN 103.A NE2 SER 99.A OG no hydrogen 3.016 N/A GLN 103.A NE2 GLY 132.A O no hydrogen 2.875 N/A LEU 104.A N TYR 100.A O no hydrogen 2.890 N/A LEU 105.A N LEU 101.A O no hydrogen 2.888 N/A GLN 106.A N PHE 102.A O no hydrogen 3.064 N/A GLN 106.A NE2 PHE 102.A O no hydrogen 3.569 N/A GLY 107.A N GLN 103.A O no hydrogen 3.058 N/A LEU 108.A N LEU 104.A O no hydrogen 2.872 N/A ALA 109.A N LEU 105.A O no hydrogen 2.782 N/A PHE 110.A N GLN 106.A O no hydrogen 3.018 N/A CYS 111.A N.A GLY 107.A O no hydrogen 3.080 N/A CYS 111.A N.B GLY 107.A O no hydrogen 3.134 N/A CYS 111.A SG.A GLY 107.A O no hydrogen 3.621 N/A CYS 111.A SG.B GLY 107.A O no hydrogen 3.458 N/A CYS 111.A SG.B LEU 108.A O no hydrogen 3.252 N/A CYS 111.A SG.B VAL 116.A O no hydrogen 3.530 N/A HIS 112.A N LEU 108.A O no hydrogen 2.742 N/A HIS 112.A NE2 ASP 178.A OD2 no hydrogen 2.866 N/A SER 113.A N ALA 109.A O no hydrogen 2.979 N/A SER 113.A OG ALA 109.A O no hydrogen 3.494 N/A SER 113.A OG PHE 110.A O no hydrogen 2.709 N/A HIS 114.A N CYS 111.A O.A no hydrogen 3.203 N/A HIS 114.A N CYS 111.A O.B no hydrogen 2.830 N/A ARG 115.A N HIS 112.A O no hydrogen 2.923 N/A VAL 116.A N CYS 111.A O.A no hydrogen 2.874 N/A VAL 116.A N CYS 111.A O.B no hydrogen 3.064 N/A HIS 118.A N ASP 178.A OD2 no hydrogen 2.885 N/A HIS 118.A NE2 ALA 137.A O no hydrogen 2.759 N/A ARG 119.A N ASP 178.A OD1 no hydrogen 2.794 N/A ARG 119.A NE ARG 119.A O no hydrogen 2.896 N/A ARG 119.A NH1 TYR 173.A OH no hydrogen 3.524 N/A ASP 120.A N HIS 118.A ND1 no hydrogen 2.979 N/A LYS 122.A N ASN 125.A OD1 no hydrogen 3.033 N/A LYS 122.A NZ ASP 120.A OD2 no hydrogen 3.046 N/A GLN 124.A N GLN 124.A OE1 no hydrogen 2.898 N/A ASN 125.A N LYS 122.A O no hydrogen 2.934 N/A ASN 125.A ND2 ASP 120.A O no hydrogen 2.889 N/A LEU 126.A N PRO 123.A O no hydrogen 3.149 N/A LEU 127.A N LYS 135.A O no hydrogen 2.886 N/A ILE 128.A N GLN 78.A O no hydrogen 2.835 N/A ASN 129.A N ALA 133.A O no hydrogen 3.158 N/A GLU 131.A N ASN 129.A OD1 no hydrogen 2.995 N/A ALA 133.A N ASN 129.A OD1 no hydrogen 2.988 N/A ILE 134.A N GLN 103.A OE1 no hydrogen 3.119 N/A LYS 135.A N LEU 127.A O no hydrogen 2.783 N/A LYS 135.A NZ GLU 74.A OE1 no hydrogen 2.750 N/A LYS 135.A NZ GLU 74.A OE2 no hydrogen 3.335 N/A LEU 136.A N ASN 55.A O no hydrogen 2.877 N/A ALA 137.A N ASN 125.A O no hydrogen 2.834 N/A LEU 141.A N ASP 138.A O no hydrogen 3.153 N/A ALA 144.A N GLY 140.A O no hydrogen 3.498 N/A PHE 145.A N LEU 141.A O no hydrogen 2.958 N/A GLY 146.A N ALA 142.A O no hydrogen 2.674 N/A ARG 150.A NH2 HIS 154.A O no hydrogen 3.147 N/A THR 151.A N GLU 155.A O.A no hydrogen 2.785 N/A THR 151.A N GLU 155.A O.B no hydrogen 2.775 N/A THR 151.A OG1 THR 153.A OG1 no hydrogen 3.209 N/A TYR 152.A N THR 17.A O no hydrogen 3.172 N/A THR 153.A N THR 151.A OG1 no hydrogen 3.169 N/A THR 153.A OG1 GLU 15.A OE1 no hydrogen 3.453 N/A THR 153.A OG1 THR 151.A OG1 no hydrogen 3.209 N/A HIS 154.A N THR 151.A O no hydrogen 2.855 N/A GLU 155.A N.A THR 151.A OG1 no hydrogen 3.145 N/A GLU 155.A N.B THR 151.A OG1 no hydrogen 3.163 N/A VAL 157.A N VAL 149.A O no hydrogen 3.033 N/A TRP 160.A N THR 158.A OG1 no hydrogen 3.258 N/A TRP 160.A NE1 GLY 198.A O no hydrogen 2.913 N/A TYR 161.A OH GLU 188.A OE1 no hydrogen 2.586 N/A ARG 162.A N LEU 159.A O no hydrogen 3.044 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.759 N/A ILE 166.A N ALA 163.A O no hydrogen 3.074 N/A LEU 167.A N ALA 163.A O no hydrogen 3.251 N/A LEU 168.A N PRO 164.A O no hydrogen 2.896 N/A GLY 169.A N ILE 166.A O no hydrogen 3.006 N/A CYS 170.A N.A GLU 165.A O no hydrogen 2.933 N/A CYS 170.A N.B GLU 165.A O no hydrogen 2.921 N/A CYS 170.A SG.A TYR 172.A O no hydrogen 3.283 N/A CYS 170.A SG.B GLU 165.A O no hydrogen 3.027 N/A CYS 170.A SG.B TYR 172.A O no hydrogen 3.545 N/A ALA 176.A N SER 174.A OG no hydrogen 3.141 N/A VAL 177.A N SER 174.A O no hydrogen 2.984 N/A ASP 178.A N THR 175.A O no hydrogen 3.078 N/A TRP 180.A N ALA 176.A O no hydrogen 3.085 N/A SER 181.A N VAL 177.A O no hydrogen 3.255 N/A SER 181.A OG TYR 161.A O no hydrogen 2.713 N/A SER 181.A OG VAL 177.A O no hydrogen 3.126 N/A LEU 182.A N ASP 178.A O no hydrogen 2.957 N/A GLY 183.A N ILE 179.A O no hydrogen 2.865 N/A CYS 184.A N TRP 180.A O no hydrogen 3.003 N/A CYS 184.A SG TRP 180.A O no hydrogen 3.556 N/A ILE 185.A N SER 181.A O no hydrogen 2.988 N/A PHE 186.A N LEU 182.A O no hydrogen 2.830 N/A ALA 187.A N GLY 183.A O no hydrogen 3.005 N/A GLU 188.A N CYS 184.A O no hydrogen 3.102 N/A MET 189.A N ILE 185.A O no hydrogen 2.939 N/A VAL 190.A N PHE 186.A O no hydrogen 3.067 N/A THR 191.A N ALA 187.A O no hydrogen 2.853 N/A THR 191.A OG1 ALA 187.A O no hydrogen 3.010 N/A ARG 192.A N GLU 188.A O no hydrogen 2.853 N/A ARG 192.A NH2 ALA 88.A O no hydrogen 3.210 N/A ARG 193.A N THR 191.A OG1 no hydrogen 3.350 N/A GLY 198.A N PHE 196.A O no hydrogen 2.912 N/A GLY 198.A N GLN 204.A OE1 no hydrogen 2.881 N/A ASP 199.A N ASP 203.A OD2 no hydrogen 3.001 N/A ASP 203.A N SER 200.A OG no hydrogen 3.022 N/A GLN 204.A N SER 200.A O no hydrogen 2.797 N/A GLN 204.A NE2 TRP 160.A O no hydrogen 3.315 N/A GLN 204.A NE2 PHE 196.A O no hydrogen 2.945 N/A LEU 205.A N.A GLU 201.A O no hydrogen 2.933 N/A LEU 205.A N.B GLU 201.A O no hydrogen 2.973 N/A PHE 206.A N ILE 202.A O no hydrogen 2.818 N/A ARG 207.A N ASP 203.A O no hydrogen 2.862 N/A ARG 207.A NE ASP 203.A OD2 no hydrogen 3.121 N/A ILE 208.A N GLN 204.A O no hydrogen 3.081 N/A PHE 209.A N LEU 205.A O.A no hydrogen 2.933 N/A PHE 209.A N LEU 205.A O.B no hydrogen 2.805 N/A ARG 210.A N PHE 206.A O no hydrogen 2.851 N/A THR 211.A N ARG 207.A O no hydrogen 3.296 N/A THR 211.A N ILE 208.A O no hydrogen 3.196 N/A THR 211.A OG1 ARG 207.A O no hydrogen 3.516 N/A LEU 212.A N ILE 208.A O no hydrogen 2.835 N/A GLY 213.A N PHE 209.A O no hydrogen 2.760 N/A THR 214.A N TRP 236.A O no hydrogen 2.947 N/A THR 214.A OG1 PRO 234.A O no hydrogen 2.673 N/A VAL 219.A N ASP 216.A OD1 no hydrogen 3.222 N/A TRP 220.A N ASP 216.A O no hydrogen 2.892 N/A GLY 222.A N GLU 217.A OE1 no hydrogen 2.681 N/A VAL 223.A N TRP 220.A O no hydrogen 2.916 N/A THR 224.A N GLU 217.A OE2 no hydrogen 2.924 N/A THR 224.A OG1 GLU 217.A OE2 no hydrogen 2.636 N/A SER 225.A N GLY 222.A O no hydrogen 3.012 N/A MET 226.A N VAL 223.A O no hydrogen 3.092 N/A ASP 228.A N LEU 168.A O no hydrogen 2.908 N/A TYR 229.A N MET 226.A O no hydrogen 3.149 N/A PHE 233.A N LYS 230.A O no hydrogen 2.937 N/A LYS 235.A NZ PRO 231.A O no hydrogen 3.063 N/A LYS 235.A NZ PHE 233.A O no hydrogen 2.878 N/A TRP 236.A N THR 214.A OG1 no hydrogen 2.884 N/A ARG 238.A NH1 LEU 212.A O no hydrogen 2.990 N/A GLN 239.A N.A THR 211.A O no hydrogen 2.772 N/A GLN 239.A N.B THR 211.A O no hydrogen 2.788 N/A SER 242.A N ASP 240.A OD1 no hydrogen 3.240 N/A SER 242.A OG ASP 240.A OD1 no hydrogen 2.958 N/A LYS 243.A N ASP 240.A O no hydrogen 2.824 N/A LYS 243.A NZ GLN 239.A OE1.B no hydrogen 2.833 N/A VAL 244.A N PHE 241.A O no hydrogen 2.994 N/A VAL 245.A N PHE 241.A O no hydrogen 2.992 N/A LEU 248.A N VAL 245.A O no hydrogen 2.998 N/A GLY 252.A N ASP 249.A OD1 no hydrogen 2.880 N/A ARG 253.A N ASP 249.A O no hydrogen 2.864 N/A ARG 253.A NH1 LEU 248.A O no hydrogen 2.637 N/A ARG 253.A NH2 GLU 250.A OE1 no hydrogen 2.963 N/A SER 254.A N GLU 250.A O no hydrogen 3.031 N/A SER 254.A OG GLN 258.A OE1 no hydrogen 3.551 N/A SER 254.A OG HIS 276.A NE2 no hydrogen 3.180 N/A LEU 255.A N ASP 251.A O no hydrogen 2.917 N/A LEU 256.A N GLY 252.A O no hydrogen 2.879 N/A SER 257.A N ARG 253.A O no hydrogen 2.845 N/A SER 257.A OG ARG 253.A O no hydrogen 3.297 N/A SER 257.A OG SER 254.A O no hydrogen 2.655 N/A GLN 258.A N SER 254.A O no hydrogen 3.094 N/A MET 259.A N LEU 255.A O no hydrogen 2.984 N/A LEU 260.A N LEU 256.A O no hydrogen 3.019 N/A LEU 260.A N SER 257.A O no hydrogen 3.294 N/A TYR 262.A OH GLY 213.A O no hydrogen 2.565 N/A ASN 265.A N ASP 263.A OD1 no hydrogen 2.821 N/A LYS 266.A N ASP 263.A O no hydrogen 2.884 N/A LYS 266.A NZ VAL 219.A O no hydrogen 3.016 N/A LYS 266.A NZ ASP 263.A OD2 no hydrogen 2.918 N/A ARG 267.A N ASP 263.A O no hydrogen 3.024 N/A ARG 267.A NE HIS 261.A O no hydrogen 2.831 N/A ARG 267.A NH1 GLU 165.A OE1 no hydrogen 3.424 N/A ARG 267.A NH1 GLU 165.A OE2 no hydrogen 2.815 N/A ARG 267.A NH1 ALA 176.A O no hydrogen 2.914 N/A ARG 267.A NH2 GLU 165.A OE1 no hydrogen 2.899 N/A ARG 267.A NH2 GLU 165.A OE2 no hydrogen 3.556 N/A ARG 267.A NH2 HIS 261.A O no hydrogen 3.190 N/A ARG 267.A NH2 TYR 262.A O no hydrogen 2.978 N/A ILE 268.A N GLN 258.A O no hydrogen 3.053 N/A ALA 272.A N SER 269.A OG no hydrogen 2.955 N/A ALA 273.A N SER 269.A O no hydrogen 2.828 N/A LEU 274.A N ALA 270.A O no hydrogen 3.043 N/A ALA 275.A N ALA 272.A O no hydrogen 3.108 N/A HIS 276.A N ALA 273.A O no hydrogen 2.907 N/A HIS 276.A NE2 SER 254.A OG no hydrogen 3.180 N/A PHE 278.A N HIS 276.A ND1 no hydrogen 2.955 N/A PHE 279.A N HIS 276.A O no hydrogen 2.993 N/A GLN 280.A N PRO 277.A O no hydrogen 2.926 N/A VAL 282.A N PHE 279.A O no hydrogen 3.028 N/A LYS 284.A NZ GLU 131.A O no hydrogen 3.344 N/A