Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5mv2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 5.A N ASN 2.A O no hydrogen 3.104 N/A GLN 6.A N LEU 3.A O no hydrogen 3.061 N/A ASN 12.A ND2 HIS 162.A O no hydrogen 2.912 N/A CYS 13.A N ASP 52.A OD2 no hydrogen 3.002 N/A CYS 13.A SG THR 42.A OG1 no hydrogen 3.517 N/A MET 16.A N CYS 13.A O no hydrogen 2.972 N/A ASN 18.A ND2 ASP 38.A O no hydrogen 3.305 N/A ARG 19.A NE THR 42.A OG1 no hydrogen 3.030 N/A ARG 19.A NH1 GLU 383.A OE1 no hydrogen 3.374 N/A ARG 19.A NH1 GLU 383.A OE2 no hydrogen 2.504 N/A ARG 19.A NH2 THR 42.A OG1 no hydrogen 3.145 N/A ARG 19.A NH2 GLU 383.A OE1 no hydrogen 2.680 N/A ASP 20.A N CYS 40.A O no hydrogen 2.869 N/A ILE 22.A N THR 42.A O no hydrogen 2.726 N/A GLY 24.A N MET 44.A O no hydrogen 2.919 N/A ALA 28.A N ALA 25.A O no hydrogen 2.955 N/A VAL 31.A N LEU 299.A O no hydrogen 2.769 N/A LEU 33.A N CYS 297.A O no hydrogen 2.806 N/A LEU 35.A N LEU 295.A O no hydrogen 2.804 N/A SER 39.A N GLU 36.A O no hydrogen 3.096 N/A CYS 40.A N SER 39.A OG no hydrogen 2.770 N/A LEU 41.A N VAL 53.A O no hydrogen 3.047 N/A THR 42.A N ASP 20.A O no hydrogen 2.769 N/A THR 42.A OG1 ASP 52.A OD1 no hydrogen 2.667 N/A ILE 43.A N LEU 51.A O no hydrogen 2.627 N/A MET 44.A N ILE 22.A O no hydrogen 2.972 N/A LYS 48.A N ALA 45.A O no hydrogen 3.089 N/A LYS 48.A NZ MET 301.A O no hydrogen 2.872 N/A LYS 48.A NZ LEU 304.A O no hydrogen 2.946 N/A THR 50.A OG1 VAL 365.A O no hydrogen 2.644 N/A LEU 51.A N ILE 43.A O no hydrogen 2.863 N/A ASP 52.A N PHE 152.A O no hydrogen 2.767 N/A VAL 53.A N LEU 41.A O no hydrogen 2.962 N/A ARG 54.A N GLY 150.A O no hydrogen 2.927 N/A ARG 54.A NE SER 39.A O no hydrogen 3.026 N/A ARG 54.A NH1 HIS 10.A O no hydrogen 3.023 N/A ARG 54.A NH2 SER 39.A O no hydrogen 3.074 N/A ILE 56.A N LYS 148.A O no hydrogen 2.671 N/A ILE 58.A N THR 291.A O no hydrogen 2.982 N/A GLU 59.A N LYS 146.A O no hydrogen 2.789 N/A ALA 60.A N MET 289.A O no hydrogen 2.819 N/A SER 61.A N ASN 144.A O no hydrogen 3.124 N/A ALA 64.A N THR 139.A O no hydrogen 3.151 N/A VAL 66.A N GLY 137.A O no hydrogen 2.757 N/A SER 68.A N THR 236.A O no hydrogen 2.720 N/A SER 68.A OG GLU 65.A OE1 no hydrogen 2.867 N/A TYR 69.A N ALA 135.A O no hydrogen 2.776 N/A TYR 69.A OH PHE 228.A O no hydrogen 2.723 N/A CYS 70.A N PRO 234.A O no hydrogen 3.044 N/A CYS 70.A SG HIS 72.A O no hydrogen 3.233 N/A CYS 70.A SG SER 133.A O no hydrogen 3.719 N/A TYR 71.A N SER 133.A O no hydrogen 2.857 N/A HIS 72.A N SER 133.A O no hydrogen 3.217 N/A SER 74.A N SER 130.A O no hydrogen 2.865 N/A SER 74.A OG SER 130.A OG no hydrogen 3.256 N/A THR 76.A N LYS 128.A O no hydrogen 2.968 N/A SER 79.A N CYS 126.A O no hydrogen 3.130 N/A THR 80.A OG1 THR 125.A OG1 no hydrogen 2.710 N/A VAL 81.A N ASP 124.A O no hydrogen 3.035 N/A ARG 83.A N SER 122.A O no hydrogen 2.749 N/A ARG 83.A NE THR 87.A O no hydrogen 3.137 N/A ARG 83.A NE THR 87.A OG1 no hydrogen 3.208 N/A ARG 83.A NH2 THR 87.A O no hydrogen 3.140 N/A CYS 84.A SG GLY 114.A O no hydrogen 3.794 N/A THR 86.A OG1 PRO 85.A O no hydrogen 2.757 N/A THR 87.A N CYS 84.A O no hydrogen 3.095 N/A THR 87.A OG1 CYS 84.A O no hydrogen 2.888 N/A ALA 90.A N SER 122.A OG no hydrogen 3.015 N/A ASN 92.A N ASP 124.A OD1 no hydrogen 2.642 N/A ASN 92.A ND2 SER 79.A OG no hydrogen 2.967 N/A ASN 92.A ND2 ASP 124.A O no hydrogen 3.432 N/A LYS 94.A N ASN 92.A OD1 no hydrogen 2.844 N/A LYS 94.A NZ TYR 100.A OH no hydrogen 3.426 N/A ARG 95.A N ASN 92.A O no hydrogen 2.939 N/A ARG 95.A NE ASP 124.A OD1 no hydrogen 2.870 N/A ARG 95.A NE ASP 124.A OD2 no hydrogen 3.362 N/A ARG 95.A NH2 ASP 124.A OD2 no hydrogen 2.718 N/A ALA 96.A N GLU 93.A O no hydrogen 3.088 N/A ASP 97.A N LYS 94.A O no hydrogen 3.086 N/A SER 99.A N ASP 97.A OD1 no hydrogen 3.089 N/A TYR 100.A N ASP 97.A O no hydrogen 3.036 N/A TYR 100.A OH ASP 77.A OD2 no hydrogen 2.451 N/A VAL 101.A N ALA 127.A O no hydrogen 2.822 N/A LYS 103.A N THR 125.A O no hydrogen 2.736 N/A GLN 104.A NE2 GLU 89.A OE1 no hydrogen 3.049 N/A GLN 104.A NE2 ALA 90.A O no hydrogen 3.067 N/A GLY 105.A N ILE 123.A O no hydrogen 2.834 N/A THR 107.A N GLY 121.A O no hydrogen 2.924 N/A THR 107.A OG1 ALA 257.A O no hydrogen 2.425 N/A ARG 109.A N GLY 119.A O no hydrogen 2.642 N/A ARG 109.A NE ASN 113.A OD1 no hydrogen 2.986 N/A ARG 109.A NH2 ASN 113.A O no hydrogen 2.820 N/A GLY 110.A N ASN 113.A OD1 no hydrogen 3.027 N/A TRP 111.A NE1 GLY 116.A O no hydrogen 2.950 N/A ASN 113.A N GLY 110.A O no hydrogen 2.982 N/A ASN 113.A ND2 ASP 108.A O no hydrogen 3.008 N/A GLY 114.A N TRP 111.A O no hydrogen 3.399 N/A CYS 115.A N GLY 110.A O no hydrogen 3.066 N/A GLY 119.A N ARG 109.A O no hydrogen 2.981 N/A LYS 120.A NZ ASP 108.A OD1 no hydrogen 2.776 N/A GLY 121.A N THR 107.A O no hydrogen 2.818 N/A ILE 123.A N GLY 105.A O no hydrogen 2.967 N/A ASP 124.A N VAL 81.A O no hydrogen 2.835 N/A THR 125.A N LYS 103.A O no hydrogen 2.989 N/A THR 125.A OG1 THR 80.A OG1 no hydrogen 2.710 N/A THR 125.A OG1 GLN 260.A OE1 no hydrogen 2.875 N/A CYS 126.A N SER 79.A O no hydrogen 3.028 N/A ALA 127.A N VAL 101.A O no hydrogen 2.875 N/A LYS 128.A N THR 76.A O no hydrogen 2.740 N/A PHE 129.A N SER 99.A O no hydrogen 2.997 N/A SER 130.A N SER 74.A O no hydrogen 2.966 N/A SER 130.A OG SER 74.A OG no hydrogen 3.256 N/A THR 132.A N HIS 72.A O no hydrogen 2.800 N/A SER 133.A N HIS 72.A O no hydrogen 3.227 N/A ALA 135.A N TYR 69.A O no hydrogen 2.704 N/A ILE 136.A N THR 215.A O no hydrogen 3.141 N/A GLY 137.A N ARG 67.A O no hydrogen 2.964 N/A ARG 138.A N VAL 213.A O no hydrogen 2.628 N/A THR 139.A N ALA 64.A O no hydrogen 2.972 N/A THR 139.A OG1 ALA 64.A O no hydrogen 3.533 N/A ASN 144.A N GLN 141.A O no hydrogen 2.919 N/A ILE 145.A N PRO 142.A O no hydrogen 3.126 N/A LYS 146.A N GLU 59.A O no hydrogen 2.759 N/A TYR 147.A N VAL 179.A O no hydrogen 2.782 N/A LYS 148.A N ASN 57.A O no hydrogen 3.009 N/A LYS 148.A NZ GLU 59.A OE2 no hydrogen 2.610 N/A VAL 149.A N PHE 177.A O no hydrogen 2.954 N/A GLY 150.A N ARG 54.A O no hydrogen 2.754 N/A ILE 151.A N ALA 175.A O no hydrogen 2.857 N/A PHE 152.A N ASP 52.A O no hydrogen 2.734 N/A VAL 153.A N GLN 173.A O no hydrogen 2.883 N/A HIS 154.A N THR 50.A O no hydrogen 2.819 N/A HIS 154.A NE2 ASP 52.A OD1 no hydrogen 2.900 N/A GLY 155.A N VAL 153.A O no hydrogen 2.653 N/A THR 156.A N GLN 173.A OE1 no hydrogen 2.927 N/A THR 156.A OG1 PHE 370.A O no hydrogen 2.833 N/A THR 157.A OG1 HIS 162.A ND1 no hydrogen 2.827 N/A THR 158.A N ASN 161.A OD1 no hydrogen 2.948 N/A SER 159.A N GLU 335.A OE2 no hydrogen 2.803 N/A SER 159.A OG GLU 335.A OE1 no hydrogen 2.914 N/A SER 159.A OG GLU 335.A OE2 no hydrogen 3.173 N/A GLU 160.A N THR 158.A OG1 no hydrogen 3.180 N/A ASN 161.A N THR 158.A O no hydrogen 3.251 N/A ASN 161.A N THR 158.A OG1 no hydrogen 3.023 N/A HIS 162.A ND1 THR 157.A OG1 no hydrogen 2.827 N/A ASN 164.A N ASN 161.A O no hydrogen 2.935 N/A SER 166.A OG ASN 164.A OD1 no hydrogen 2.764 N/A ALA 167.A N ASN 164.A OD1 no hydrogen 2.902 N/A GLN 168.A N ASN 164.A O no hydrogen 2.988 N/A GLN 168.A NE2 ASN 161.A O no hydrogen 2.935 N/A GLN 168.A NE2 ASN 161.A OD1 no hydrogen 3.033 N/A VAL 169.A N TYR 165.A O no hydrogen 2.881 N/A GLY 170.A N SER 166.A O no hydrogen 2.978 N/A ALA 171.A N ALA 167.A O no hydrogen 3.005 N/A SER 172.A N VAL 169.A O no hydrogen 2.831 N/A GLN 173.A N GLN 168.A O no hydrogen 2.849 N/A GLN 173.A NE2 THR 156.A O no hydrogen 2.875 N/A GLN 173.A NE2 GLN 168.A OE1 no hydrogen 2.808 N/A ALA 175.A N ILE 151.A O no hydrogen 3.018 N/A PHE 177.A N VAL 149.A O no hydrogen 3.027 N/A VAL 179.A N TYR 147.A O no hydrogen 2.934 N/A THR 180.A N ALA 183.A O no hydrogen 3.285 N/A ALA 183.A N THR 180.A O no hydrogen 3.023 N/A ALA 183.A N THR 180.A OG1 no hydrogen 2.926 N/A SER 185.A OG LEU 198.A O no hydrogen 3.554 N/A VAL 186.A N LEU 198.A O no hydrogen 2.728 N/A LEU 188.A N VAL 196.A O no hydrogen 2.993 N/A LYS 189.A NZ GLU 195.A OE1 no hydrogen 3.429 N/A LEU 190.A N GLY 194.A O no hydrogen 2.791 N/A TYR 193.A N LEU 190.A O no hydrogen 2.829 N/A GLU 195.A N LYS 303.A O no hydrogen 3.194 N/A VAL 196.A N LEU 188.A O no hydrogen 2.990 N/A THR 197.A N LYS 300.A O no hydrogen 3.422 N/A LEU 198.A N VAL 186.A O no hydrogen 2.650 N/A ASP 199.A N ARG 298.A O no hydrogen 2.879 N/A CYS 200.A N PRO 184.A O no hydrogen 2.916 N/A GLU 201.A N LYS 296.A O no hydrogen 3.039 N/A SER 204.A N GLU 201.A O no hydrogen 3.106 N/A SER 204.A OG GLU 201.A O no hydrogen 3.563 N/A SER 204.A OG GLU 201.A OE1 no hydrogen 3.110 N/A GLY 205.A N PRO 202.A O no hydrogen 3.070 N/A LEU 206.A N ARG 203.A O no hydrogen 3.124 N/A THR 208.A OG1 GLU 209.A OE2 no hydrogen 2.696 N/A ALA 210.A N ASN 207.A O no hydrogen 2.971 N/A TYR 212.A N VAL 223.A O no hydrogen 2.990 N/A TYR 212.A OH HIS 229.A NE2 no hydrogen 2.798 N/A VAL 213.A N ARG 138.A O no hydrogen 2.678 N/A MET 214.A N PHE 221.A O no hydrogen 2.791 N/A THR 215.A N ILE 136.A O no hydrogen 2.836 N/A THR 215.A OG1 SER 220.A OG no hydrogen 2.685 N/A VAL 216.A N LYS 219.A O no hydrogen 2.730 N/A LYS 219.A N VAL 216.A O no hydrogen 3.106 N/A SER 220.A OG THR 215.A OG1 no hydrogen 2.685 N/A PHE 221.A N MET 214.A O no hydrogen 2.855 N/A LEU 222.A N ILE 280.A O no hydrogen 2.895 N/A VAL 223.A N TYR 212.A O no hydrogen 2.919 N/A ARG 225.A NE PHE 211.A O no hydrogen 2.872 N/A ARG 225.A NH2 PHE 211.A O no hydrogen 3.262 N/A PHE 228.A N HIS 224.A O no hydrogen 3.166 N/A HIS 229.A N ARG 225.A O no hydrogen 2.949 N/A ASP 230.A N GLU 226.A O no hydrogen 3.322 N/A ASP 230.A N TRP 227.A O no hydrogen 3.265 N/A LEU 233.A N LEU 231.A O no hydrogen 3.009 N/A TRP 235.A N ARG 244.A O no hydrogen 3.050 N/A THR 236.A N SER 68.A O no hydrogen 2.918 N/A SER 237.A N SER 240.A O no hydrogen 3.063 N/A SER 237.A OG SER 239.A OG no hydrogen 3.315 N/A SER 239.A OG SER 237.A OG no hydrogen 3.315 N/A SER 240.A N SER 237.A O no hydrogen 2.811 N/A ARG 244.A N TRP 235.A O no hydrogen 2.879 N/A ARG 246.A NH1 SER 98.A O no hydrogen 2.693 N/A GLU 247.A N GLU 247.A OE1 no hydrogen 2.644 N/A LEU 248.A N ASN 245.A O no hydrogen 3.133 N/A LEU 249.A N ARG 246.A O no hydrogen 3.241 N/A MET 250.A N GLU 247.A O no hydrogen 2.942 N/A GLU 251.A N VAL 263.A O no hydrogen 2.947 N/A GLU 253.A N SER 261.A O no hydrogen 2.897 N/A HIS 256.A N LYS 259.A O no hydrogen 2.983 N/A LYS 259.A N HIS 256.A O no hydrogen 2.769 N/A GLN 260.A NE2 GLU 253.A O no hydrogen 2.623 N/A SER 261.A OG GLU 253.A OE1 no hydrogen 2.723 N/A VAL 263.A N GLU 251.A O no hydrogen 3.084 N/A LEU 265.A N LEU 249.A O no hydrogen 2.970 N/A GLN 268.A N TYR 71.A O no hydrogen 2.676 N/A GLN 268.A NE2 GLY 266.A O no hydrogen 2.848 N/A GLU 269.A N SER 267.A OG no hydrogen 3.176 N/A LEU 272.A N GLN 268.A O no hydrogen 3.014 N/A HIS 273.A N GLU 269.A O no hydrogen 2.877 N/A HIS 273.A NE2 GLU 269.A OE2 no hydrogen 2.976 N/A HIS 274.A N GLY 270.A O no hydrogen 2.915 N/A ALA 275.A N GLY 271.A O no hydrogen 3.004 N/A LEU 276.A N LEU 272.A O no hydrogen 3.015 N/A ALA 277.A N HIS 274.A O no hydrogen 3.032 N/A ALA 279.A N LEU 276.A O no hydrogen 2.951 N/A VAL 282.A N SER 220.A O no hydrogen 3.064 N/A GLU 283.A N LEU 290.A O no hydrogen 3.133 N/A SER 286.A OG VAL 288.A O no hydrogen 3.539 N/A MET 289.A N ALA 60.A O no hydrogen 2.824 N/A LEU 290.A N GLU 283.A O no hydrogen 2.836 N/A THR 291.A N ILE 58.A O no hydrogen 2.816 N/A THR 291.A OG1 SER 292.A O no hydrogen 3.534 N/A SER 292.A N THR 291.A OG1 no hydrogen 2.715 N/A LEU 295.A N LEU 35.A O no hydrogen 2.907 N/A CYS 297.A N LEU 33.A O no hydrogen 2.864 N/A ARG 298.A N ASP 199.A O no hydrogen 2.717 N/A ARG 298.A NE ASP 32.A OD1 no hydrogen 3.064 N/A LEU 299.A N VAL 31.A O no hydrogen 2.726 N/A LYS 300.A N THR 197.A O no hydrogen 2.819 N/A MET 301.A N THR 29.A O no hydrogen 2.698 N/A LEU 304.A N MET 301.A O no hydrogen 3.047 N/A ALA 305.A N TYR 193.A O no hydrogen 2.756 N/A LYS 307.A NZ TYR 311.A OH no hydrogen 2.837 N/A TYR 311.A N GLY 308.A O no hydrogen 3.328 N/A CYS 314.A N LYS 346.A O no hydrogen 2.798 N/A CYS 314.A SG LYS 346.A O no hydrogen 3.209 N/A THR 315.A N ASP 342.A OD2 no hydrogen 3.369 N/A THR 315.A OG1 GLU 316.A OE2 no hydrogen 2.673 N/A THR 315.A OG1 ASP 342.A OD2 no hydrogen 3.192 N/A GLU 316.A N TYR 338.A OH no hydrogen 2.959 N/A LYS 317.A NZ PHE 318.A O no hydrogen 2.754 N/A SER 319.A N SER 337.A O no hydrogen 2.918 N/A LYS 322.A N GLU 335.A O no hydrogen 3.016 N/A VAL 325.A N VAL 333.A O no hydrogen 3.068 N/A THR 327.A N THR 331.A O no hydrogen 2.889 N/A THR 327.A OG1 THR 331.A O no hydrogen 3.155 N/A THR 327.A OG1 THR 331.A OG1 no hydrogen 2.668 N/A GLY 328.A N ASP 326.A OD2 no hydrogen 2.704 N/A HIS 329.A N THR 327.A OG1 no hydrogen 3.208 N/A THR 331.A OG1 THR 327.A OG1 no hydrogen 2.668 N/A THR 331.A OG1 GLU 383.A OE2 no hydrogen 2.511 N/A VAL 332.A N MET 384.A O no hydrogen 2.800 N/A VAL 333.A N VAL 325.A O no hydrogen 2.938 N/A ILE 334.A N VAL 382.A O no hydrogen 2.996 N/A GLU 335.A N LYS 322.A O no hydrogen 3.286 N/A LEU 336.A N VAL 380.A O no hydrogen 2.684 N/A SER 337.A N SER 319.A O no hydrogen 2.735 N/A TYR 338.A N SER 378.A O no hydrogen 2.903 N/A TYR 338.A OH ASP 342.A OD1 no hydrogen 2.777 N/A TYR 338.A OH ASP 342.A OD2 no hydrogen 3.394 N/A SER 339.A N LYS 317.A O no hydrogen 3.124 N/A SER 339.A OG LYS 317.A O no hydrogen 2.835 N/A ASP 342.A N ASP 342.A OD1 no hydrogen 2.434 N/A CYS 345.A N VAL 371.A O no hydrogen 3.082 N/A LYS 346.A N GLY 312.A O no hydrogen 2.840 N/A ILE 347.A N PRO 369.A O no hydrogen 3.004 N/A VAL 350.A N VAL 394.A O no hydrogen 3.034 N/A VAL 352.A N TYR 392.A O no hydrogen 3.026 N/A ASP 357.A N SER 354.A O no hydrogen 3.060 N/A ASP 357.A N SER 354.A OG no hydrogen 3.341 N/A THR 359.A OG1 ASP 357.A OD1 no hydrogen 2.634 N/A VAL 361.A N SER 351.A O no hydrogen 2.792 N/A ARG 363.A N GLU 385.A O no hydrogen 3.170 N/A ARG 363.A NE GLU 385.A OE2 no hydrogen 3.059 N/A ARG 363.A NH1 GLU 23.A OE2 no hydrogen 3.172 N/A ARG 363.A NH2 GLU 23.A OE1 no hydrogen 2.628 N/A ARG 363.A NH2 GLU 385.A OE2 no hydrogen 3.135 N/A VAL 365.A N GLU 383.A O no hydrogen 2.983 N/A THR 366.A N GLU 383.A O no hydrogen 3.194 N/A THR 366.A OG1 GLU 383.A O no hydrogen 3.444 N/A VAL 371.A N CYS 345.A O no hydrogen 2.982 N/A SER 375.A N THR 373.A OG1 no hydrogen 2.948 N/A ASN 377.A N TYR 338.A O no hydrogen 2.692 N/A VAL 380.A N LEU 336.A O no hydrogen 2.890 N/A LEU 381.A N THR 157.A O no hydrogen 2.852 N/A VAL 382.A N ILE 334.A O no hydrogen 2.987 N/A GLU 383.A N THR 366.A OG1 no hydrogen 2.704 N/A MET 384.A N VAL 332.A O no hydrogen 2.807 N/A GLU 385.A N ARG 363.A O no hydrogen 2.817 N/A GLY 389.A N LYS 408.A O no hydrogen 2.914 N/A SER 391.A N TRP 406.A O no hydrogen 3.001 N/A TYR 392.A N VAL 352.A O no hydrogen 2.802 N/A ILE 393.A N HIS 404.A O no hydrogen 2.906 N/A VAL 394.A N VAL 350.A O no hydrogen 2.743 N/A VAL 395.A N ILE 402.A O no hydrogen 2.728 N/A GLY 396.A N PRO 348.A O no hydrogen 2.843 N/A LYS 400.A NZ GLU 316.A OE1 no hydrogen 3.100 N/A ILE 402.A N VAL 395.A O no hydrogen 2.894 N/A HIS 404.A N ILE 393.A O no hydrogen 2.891 N/A HIS 404.A ND1 HIS 405.A O no hydrogen 2.731 N/A TRP 406.A N SER 391.A O no hydrogen 2.918 N/A HIS 407.A ND1 ASP 390.A OD1 no hydrogen 2.931 N/A LYS 408.A N GLY 389.A O no hydrogen 3.084 N/A LYS 408.A NZ PRO 386.A O no hydrogen 2.637 N/A