Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5n0d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 4.A N GLY 1.A O no hydrogen 3.048 N/A GLY 7.A N ASN 12.A O no hydrogen 2.853 N/A GLY 9.A N ASN 12.A OD1 no hydrogen 2.809 N/A ASN 12.A ND2 HIS 5.A O no hydrogen 3.235 N/A HIS 16.A N GLY 13.A O no hydrogen 2.780 N/A HIS 16.A NE2 LYS 10.A O no hydrogen 3.103 N/A TRP 17.A NE1 GLY 7.A O no hydrogen 3.078 N/A TRP 17.A NE1 ASN 12.A O no hydrogen 3.082 N/A LYS 19.A N HIS 16.A O no hydrogen 3.068 N/A LYS 19.A NZ HIS 16.A ND1 no hydrogen 2.873 N/A ASP 20.A N TRP 17.A O no hydrogen 3.119 N/A PHE 21.A N TRP 17.A O no hydrogen 2.863 N/A ALA 24.A N PHE 21.A O no hydrogen 2.857 N/A LYS 25.A N PRO 22.A O no hydrogen 3.206 N/A GLY 26.A N ILE 23.A O no hydrogen 2.675 N/A ARG 28.A N GLU 205.A OE2 no hydrogen 3.037 N/A ARG 28.A NE GLY 196.A O no hydrogen 2.987 N/A ARG 28.A NH1 PRO 138.A O no hydrogen 3.492 N/A ARG 28.A NH2 PRO 138.A O no hydrogen 3.226 N/A ARG 28.A NH2 GLY 196.A O no hydrogen 2.914 N/A ARG 28.A NH2 VAL 207.A O no hydrogen 3.109 N/A GLN 29.A NE2 LEU 203.A O no hydrogen 3.160 N/A GLN 29.A NE2 GLU 205.A OE2 no hydrogen 3.051 N/A SER 30.A N SER 197.A OG no hydrogen 3.016 N/A SER 30.A OG TYR 194.A OH no hydrogen 2.752 N/A SER 30.A OG SER 197.A O no hydrogen 3.557 N/A ILE 34.A N THR 109.A O no hydrogen 2.766 N/A THR 36.A N ASP 111.A OD1 no hydrogen 2.875 N/A THR 36.A OG1 ASP 111.A OD1 no hydrogen 3.251 N/A THR 36.A OG1 ASP 111.A OD2 no hydrogen 2.678 N/A THR 38.A N ASP 35.A O no hydrogen 2.949 N/A THR 38.A OG1 ASP 35.A OD2 no hydrogen 2.713 N/A ALA 39.A N ASP 35.A O no hydrogen 3.014 N/A LYS 40.A N ILE 256.A O no hydrogen 3.341 N/A ASP 42.A N ALA 258.A O no hydrogen 2.936 N/A SER 44.A N ASP 42.A OD1 no hydrogen 3.047 N/A SER 44.A OG ASP 42.A OD1 no hydrogen 2.529 N/A LEU 45.A N ASP 42.A O no hydrogen 2.992 N/A SER 49.A N LYS 81.A O no hydrogen 2.826 N/A SER 51.A N VAL 79.A O no hydrogen 2.970 N/A TYR 52.A OH HIS 123.A NE2 no hydrogen 2.661 N/A ALA 55.A N TYR 52.A O no hydrogen 2.938 N/A THR 56.A OG1 GLN 54.A O no hydrogen 3.320 N/A SER 57.A OG PHE 176.A O no hydrogen 2.725 N/A LEU 58.A N GLU 70.A O no hydrogen 2.798 N/A ARG 59.A NE GLU 70.A OE1 no hydrogen 2.791 N/A ARG 59.A NH2 GLU 70.A OE1 no hydrogen 3.095 N/A ARG 59.A NH2 GLU 70.A OE2 no hydrogen 2.803 N/A ILE 60.A N ALA 174.A O no hydrogen 2.933 N/A LEU 61.A N ASN 68.A O no hydrogen 2.854 N/A ASN 62.A N LYS 172.A O no hydrogen 2.971 N/A ASN 62.A ND2 ILE 167.A O no hydrogen 3.109 N/A ASN 62.A ND2 ASN 230.A O no hydrogen 3.267 N/A ASN 63.A N ALA 66.A O no hydrogen 3.069 N/A GLY 64.A N ASN 62.A OD1 no hydrogen 2.833 N/A HIS 65.A N ASN 63.A OD1 no hydrogen 2.834 N/A ALA 66.A N ASN 63.A OD1 no hydrogen 2.897 N/A ASN 68.A N LEU 61.A O no hydrogen 2.755 N/A VAL 69.A N PHE 94.A O no hydrogen 2.920 N/A GLU 70.A N ARG 59.A O no hydrogen 2.777 N/A PHE 71.A N ILE 92.A O no hydrogen 2.972 N/A ASP 72.A N THR 56.A O no hydrogen 2.750 N/A SER 74.A N ASP 72.A OD1 no hydrogen 2.938 N/A SER 74.A OG ASP 72.A OD1 no hydrogen 2.744 N/A SER 74.A OG ASP 72.A OD2 no hydrogen 3.553 N/A LYS 77.A NZ ASP 72.A OD2 no hydrogen 2.774 N/A VAL 79.A N SER 51.A O no hydrogen 2.987 N/A LEU 80.A N TYR 89.A O no hydrogen 2.769 N/A LYS 81.A N SER 49.A O no hydrogen 2.978 N/A GLY 83.A N PRO 47.A O no hydrogen 3.101 N/A LEU 85.A N GLY 82.A O no hydrogen 2.990 N/A TYR 89.A N LEU 80.A O no hydrogen 2.998 N/A TYR 89.A OH ASP 139.A O no hydrogen 3.030 N/A ARG 90.A N TRP 124.A O no hydrogen 2.801 N/A ARG 90.A NE ASP 76.A OD1 no hydrogen 2.933 N/A ARG 90.A NH1 ASP 73.A O no hydrogen 2.860 N/A ARG 90.A NH2 ASP 76.A OD1 no hydrogen 2.540 N/A LEU 91.A N ALA 78.A O no hydrogen 2.921 N/A ILE 92.A N VAL 122.A O no hydrogen 2.936 N/A PHE 94.A N VAL 69.A O no hydrogen 3.010 N/A HIS 95.A N HIS 120.A O no hydrogen 2.996 N/A HIS 95.A ND1 GLN 93.A OE1 no hydrogen 2.787 N/A HIS 97.A N GLU 118.A O no hydrogen 2.977 N/A HIS 97.A ND1 ASN 244.A O no hydrogen 2.775 N/A TRP 98.A N ASN 244.A OD1 no hydrogen 2.771 N/A TRP 98.A NE1 MET 241.A O no hydrogen 2.897 N/A SER 100.A N ASP 243.A OD1 no hydrogen 3.014 N/A SER 100.A OG ASP 243.A OD1 no hydrogen 3.545 N/A SER 100.A OG ASP 243.A OD2 no hydrogen 2.730 N/A GLN 104.A N LEU 101.A O no hydrogen 3.197 N/A GLN 104.A NE2 ASP 243.A OD1 no hydrogen 2.824 N/A SER 106.A N TYR 115.A O no hydrogen 2.949 N/A SER 106.A OG HIS 108.A O no hydrogen 2.761 N/A GLU 107.A N GLU 118.A OE1 no hydrogen 2.779 N/A HIS 108.A N GLU 118.A OE1 no hydrogen 2.703 N/A HIS 108.A ND1 GLU 118.A OE2 no hydrogen 2.725 N/A HIS 108.A NE2 TYR 194.A OH no hydrogen 2.644 N/A THR 109.A N VAL 32.A O no hydrogen 3.490 N/A THR 109.A OG1 ASP 33.A OD1 no hydrogen 2.653 N/A VAL 110.A N LYS 113.A O no hydrogen 3.101 N/A ASP 111.A N ILE 34.A O no hydrogen 2.851 N/A LYS 112.A N ASP 33.A OD1 no hydrogen 2.686 N/A LYS 113.A N VAL 110.A O no hydrogen 2.855 N/A TYR 115.A N SER 106.A OG no hydrogen 2.980 N/A ALA 117.A N LEU 148.A O no hydrogen 3.379 N/A GLU 118.A N HIS 97.A O no hydrogen 2.920 N/A LEU 119.A N ILE 146.A O no hydrogen 2.758 N/A HIS 120.A N HIS 95.A O no hydrogen 2.774 N/A HIS 120.A NE2 GLU 118.A OE2 no hydrogen 2.650 N/A LEU 121.A N LEU 144.A O no hydrogen 2.927 N/A VAL 122.A N GLN 93.A O no hydrogen 2.840 N/A HIS 123.A N ALA 142.A O no hydrogen 2.904 N/A HIS 123.A ND1 ALA 142.A O no hydrogen 3.067 N/A HIS 123.A NE2 TYR 52.A OH no hydrogen 2.661 N/A TRP 124.A N ARG 90.A O no hydrogen 2.910 N/A TRP 124.A NE1 ASP 73.A OD2 no hydrogen 2.758 N/A ASN 125.A N GLY 140.A O no hydrogen 2.822 N/A ASN 125.A ND2 ASP 139.A O no hydrogen 3.288 N/A THR 126.A N THR 88.A O no hydrogen 2.949 N/A THR 126.A OG1 THR 88.A O no hydrogen 3.204 N/A LYS 127.A N ASN 125.A OD1 no hydrogen 3.079 N/A TYR 128.A N ASN 125.A O no hydrogen 3.000 N/A TYR 128.A OH ASP 139.A OD1 no hydrogen 2.603 N/A GLY 129.A N THR 126.A O no hydrogen 3.165 N/A ASP 130.A N TYR 128.A O no hydrogen 2.940 N/A LYS 133.A N ASP 130.A OD1 no hydrogen 2.657 N/A ALA 134.A N ASP 130.A O no hydrogen 2.935 N/A VAL 135.A N PHE 131.A O no hydrogen 3.031 N/A GLN 136.A N LYS 133.A O no hydrogen 3.128 N/A GLN 136.A NE2 GLY 132.A O no hydrogen 3.013 N/A GLN 137.A N ALA 134.A O no hydrogen 2.881 N/A GLN 137.A NE2 LYS 133.A O no hydrogen 3.149 N/A GLY 140.A N GLN 137.A O no hydrogen 3.149 N/A LEU 141.A N CYS 206.A O no hydrogen 2.814 N/A ALA 142.A N HIS 123.A O no hydrogen 2.894 N/A VAL 143.A N THR 208.A O no hydrogen 3.140 N/A LEU 144.A N LEU 121.A O no hydrogen 2.902 N/A GLY 145.A N ILE 210.A O no hydrogen 2.807 N/A ILE 146.A N LEU 119.A O no hydrogen 2.898 N/A LEU 148.A N ALA 117.A O no hydrogen 2.917 N/A LYS 149.A N ILE 216.A O no hydrogen 3.032 N/A GLY 151.A N VAL 218.A O no hydrogen 2.741 N/A SER 152.A OG.A SER 217.A OG.B no hydrogen 2.895 N/A LYS 154.A N GLN 222.A OE1 no hydrogen 2.978 N/A LYS 154.A NZ LEU 185.A O no hydrogen 3.405 N/A LEU 157.A N LYS 154.A O no hydrogen 3.013 N/A GLN 158.A N PRO 155.A O no hydrogen 3.118 N/A GLN 158.A NE2 ASP 162.A OD1 no hydrogen 3.072 N/A GLN 158.A NE2 ASP 162.A OD2 no hydrogen 3.204 N/A LYS 159.A NZ ASN 178.A O no hydrogen 3.296 N/A VAL 160.A N LEU 157.A O no hydrogen 2.905 N/A VAL 161.A N LEU 157.A O no hydrogen 3.130 N/A ASP 162.A N GLN 158.A O no hydrogen 2.913 N/A VAL 163.A N VAL 160.A O no hydrogen 3.177 N/A LEU 164.A N VAL 161.A O no hydrogen 3.374 N/A SER 166.A N VAL 163.A O no hydrogen 2.971 N/A SER 166.A OG VAL 163.A O no hydrogen 2.666 N/A ILE 167.A N LEU 164.A O no hydrogen 3.052 N/A LYS 168.A NZ GLU 238.A OE2 no hydrogen 3.496 N/A LYS 170.A N ASN 232.A O no hydrogen 2.929 N/A GLY 171.A N ASN 62.A O no hydrogen 2.807 N/A LYS 172.A N THR 169.A O no hydrogen 3.105 N/A ALA 174.A N ILE 60.A O no hydrogen 2.858 N/A PHE 176.A N LEU 58.A O no hydrogen 2.948 N/A PHE 179.A N SER 57.A OG no hydrogen 2.811 N/A ARG 182.A N ASP 180.A OD1 no hydrogen 2.901 N/A ARG 182.A NE ASP 180.A OD1 no hydrogen 3.000 N/A ARG 182.A NE ASP 180.A OD2 no hydrogen 3.021 N/A ARG 182.A NH2 ASP 180.A OD2 no hydrogen 2.784 N/A GLY 183.A N ASP 180.A O no hydrogen 3.131 N/A LEU 184.A N PRO 181.A O no hydrogen 2.969 N/A LEU 185.A N ARG 182.A O no hydrogen 3.428 N/A GLU 187.A N GLU 214.A OE2 no hydrogen 3.097 N/A SER 188.A N GLU 214.A OE1 no hydrogen 2.838 N/A ASP 190.A N SER 188.A OG no hydrogen 3.106 N/A TYR 191.A N SER 259.A OG no hydrogen 2.920 N/A TRP 192.A N VAL 211.A O no hydrogen 2.864 N/A THR 193.A N LYS 257.A O no hydrogen 2.778 N/A THR 193.A OG1 TRP 209.A O no hydrogen 2.722 N/A TYR 194.A N TRP 209.A O no hydrogen 3.216 N/A TYR 194.A OH SER 30.A OG no hydrogen 2.752 N/A TYR 194.A OH HIS 108.A NE2 no hydrogen 2.644 N/A GLY 196.A N VAL 207.A O no hydrogen 2.768 N/A SER 197.A N SER 30.A OG no hydrogen 3.014 N/A SER 197.A OG LEU 198.A O no hydrogen 2.834 N/A LEU 198.A N LEU 204.A O no hydrogen 2.892 N/A THR 199.A OG1 GLU 107.A OE1 no hydrogen 2.600 N/A THR 199.A OG1 GLU 107.A OE2 no hydrogen 3.417 N/A THR 200.A OG1 PRO 201.A O no hydrogen 3.178 N/A LEU 203.A N THR 200.A O no hydrogen 2.821 N/A CYS 206.A SG LEU 204.A O no hydrogen 3.728 N/A VAL 207.A N GLY 196.A O no hydrogen 3.248 N/A THR 208.A N LEU 141.A O no hydrogen 2.863 N/A TRP 209.A N TYR 194.A O no hydrogen 2.978 N/A TRP 209.A NE1 SER 197.A O no hydrogen 2.929 N/A ILE 210.A N VAL 143.A O no hydrogen 3.051 N/A VAL 211.A N TRP 192.A O no hydrogen 2.860 N/A LEU 212.A N GLY 145.A O no hydrogen 2.934 N/A LYS 213.A N ASP 190.A O no hydrogen 2.919 N/A LYS 213.A NZ ASP 190.A OD2 no hydrogen 2.944 N/A ILE 216.A N PHE 147.A O no hydrogen 2.917 N/A SER 217.A OG.B SER 152.A OG.A no hydrogen 2.895 N/A VAL 218.A N LYS 149.A O no hydrogen 2.940 N/A SER 219.A N GLN 222.A OE1 no hydrogen 3.053 N/A SER 219.A OG GLU 221.A OE1 no hydrogen 3.475 N/A SER 220.A OG.A GLU 221.A OE1 no hydrogen 3.251 N/A SER 220.A OG.A GLU 221.A OE2 no hydrogen 3.371 N/A GLN 222.A N SER 219.A OG no hydrogen 3.129 N/A GLN 222.A NE2 LYS 154.A O no hydrogen 2.973 N/A GLN 222.A NE2 GLN 158.A OE1 no hydrogen 2.982 N/A VAL 223.A N SER 219.A O no hydrogen 3.163 N/A LEU 224.A N SER 220.A O.A no hydrogen 2.891 N/A LEU 224.A N SER 220.A O.B no hydrogen 2.893 N/A LYS 225.A N GLU 221.A O no hydrogen 3.171 N/A LYS 225.A N GLN 222.A O no hydrogen 3.144 N/A LYS 225.A NZ VAL 161.A O no hydrogen 2.873 N/A LYS 225.A NZ ASP 165.A OD1 no hydrogen 2.695 N/A PHE 226.A N GLN 222.A O no hydrogen 3.452 N/A ARG 227.A N VAL 223.A O no hydrogen 3.241 N/A ARG 227.A NE GLY 99.A O no hydrogen 2.836 N/A ARG 227.A NH1 ASP 102.A OD1 no hydrogen 3.549 N/A ARG 227.A NH2 ASP 102.A OD1 no hydrogen 2.717 N/A LYS 228.A N LYS 225.A O no hydrogen 3.079 N/A LEU 229.A N PHE 226.A O no hydrogen 3.274 N/A ASN 230.A N LYS 168.A O no hydrogen 2.792 N/A ASN 230.A ND2 GLU 238.A OE2 no hydrogen 2.957 N/A PHE 231.A N GLU 239.A O no hydrogen 2.852 N/A ASN 232.A ND2 GLY 233.A O no hydrogen 2.908 N/A GLY 233.A N GLU 236.A OE1 no hydrogen 2.714 N/A GLU 236.A N GLY 233.A O no hydrogen 3.153 N/A GLU 239.A N ASN 232.A OD1 no hydrogen 2.772 N/A MET 241.A N LEU 229.A O no hydrogen 2.749 N/A ASN 244.A N TRP 98.A O no hydrogen 3.323 N/A ASN 244.A ND2 HIS 65.A O no hydrogen 2.905 N/A TRP 245.A NE1 ASP 243.A OD1 no hydrogen 3.077 N/A ARG 246.A N GLU 107.A OE2 no hydrogen 2.790 N/A ARG 246.A NH1 GLN 29.A OE1 no hydrogen 2.738 N/A ARG 246.A NH1 SER 30.A O no hydrogen 2.838 N/A ARG 246.A NH2 ALA 24.A O no hydrogen 3.103 N/A ARG 246.A NH2 GLN 29.A OE1 no hydrogen 3.412 N/A GLN 249.A N PRO 31.A O no hydrogen 2.775 N/A GLN 249.A NE2 PRO 247.A O no hydrogen 2.805 N/A LYS 252.A NZ LYS 25.A O no hydrogen 3.153 N/A LYS 252.A NZ GLY 26.A O no hydrogen 2.873 N/A ARG 254.A NE LEU 251.A O no hydrogen 2.853 N/A ARG 254.A NH1 GLN 29.A O no hydrogen 2.983 N/A ARG 254.A NH1 PRO 195.A O no hydrogen 2.924 N/A ARG 254.A NH2 GLN 29.A O no hydrogen 2.872 N/A ARG 254.A NH2 PRO 250.A O no hydrogen 2.933 N/A ARG 254.A NH2 LEU 251.A O no hydrogen 3.488 N/A LYS 257.A N THR 193.A O no hydrogen 2.953 N/A ALA 258.A N LYS 40.A O no hydrogen 2.911 N/A SER 259.A N TYR 191.A O no hydrogen 2.867 N/A SER 259.A OG TYR 191.A O no hydrogen 3.368 N/A