Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5o8u_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 5.A N VAL 16.A O no hydrogen 2.885 N/A TYR 5.A OH TYR 20.A O no hydrogen 2.530 N/A GLN 7.A N TRP 14.A O no hydrogen 3.012 N/A LEU 9.A N THR 12.A O no hydrogen 2.742 N/A THR 12.A OG1 LEU 9.A O no hydrogen 3.464 N/A THR 12.A OG1 ASN 10.A O no hydrogen 3.519 N/A TRP 14.A N GLN 7.A O no hydrogen 2.752 N/A GLU 15.A N TYR 95.A OH no hydrogen 2.892 N/A VAL 16.A N TYR 5.A O no hydrogen 3.096 N/A GLU 18.A N THR 3.A O no hydrogen 2.966 N/A ARG 19.A NE ASP 35.A OD1 no hydrogen 2.647 N/A ARG 19.A NE ASP 35.A OD2 no hydrogen 3.316 N/A ARG 19.A NH2 ASP 35.A OD1 no hydrogen 3.548 N/A ARG 19.A NH2 ASP 35.A OD2 no hydrogen 2.743 N/A TYR 20.A N PRO 17.A O no hydrogen 2.948 N/A TYR 20.A OH ASP 80.A OD1 no hydrogen 2.741 N/A GLN 21.A N PHE 34.A O no hydrogen 2.939 N/A GLN 21.A NE2 GLU 18.A O no hydrogen 2.788 N/A SER 24.A N ALA 32.A O no hydrogen 2.774 N/A VAL 26.A N VAL 30.A O no hydrogen 2.879 N/A SER 29.A N LYS 46.A O no hydrogen 3.135 N/A VAL 30.A N GLY 27.A O no hydrogen 2.783 N/A CYS 31.A N VAL 44.A O no hydrogen 2.885 N/A ALA 32.A N SER 24.A O no hydrogen 2.751 N/A ALA 33.A N VAL 42.A O no hydrogen 2.851 N/A PHE 34.A N GLN 21.A O no hydrogen 2.646 N/A ASP 35.A N LEU 40.A O no hydrogen 2.731 N/A THR 36.A N ARG 19.A O no hydrogen 2.888 N/A THR 36.A OG1 ARG 19.A O no hydrogen 3.130 N/A LYS 37.A N ASP 35.A OD1 no hydrogen 3.109 N/A THR 38.A N ASP 35.A O no hydrogen 2.924 N/A THR 38.A OG1 ASP 35.A OD2 no hydrogen 2.983 N/A LEU 40.A N THR 38.A OG1 no hydrogen 3.303 N/A VAL 42.A N ALA 33.A O no hydrogen 2.823 N/A ALA 43.A N THR 98.A O no hydrogen 2.756 N/A VAL 44.A N CYS 31.A O no hydrogen 2.819 N/A LYS 45.A N LEU 96.A O no hydrogen 2.759 N/A LYS 45.A NZ GLU 63.A OE1 no hydrogen 3.536 N/A LYS 46.A N SER 29.A O no hydrogen 3.000 N/A LYS 46.A NZ ILE 13.A O no hydrogen 2.948 N/A LEU 47.A N VAL 94.A O no hydrogen 2.844 N/A GLN 52.A N ARG 49.A O no hydrogen 3.277 N/A HIS 56.A N SER 53.A OG no hydrogen 2.998 N/A HIS 56.A ND1 ARG 49.A O no hydrogen 2.886 N/A ALA 57.A N SER 53.A O no hydrogen 2.833 N/A LYS 58.A N ILE 54.A O no hydrogen 2.884 N/A LYS 58.A NZ GLU 307.A O no hydrogen 2.823 N/A LYS 58.A NZ ARG 309.A O no hydrogen 3.152 N/A ARG 59.A N ILE 55.A O no hydrogen 3.079 N/A THR 60.A N HIS 56.A O no hydrogen 2.958 N/A THR 60.A OG1 PRO 50.A O no hydrogen 3.107 N/A THR 60.A OG1 HIS 56.A O no hydrogen 2.940 N/A TYR 61.A N ALA 57.A O no hydrogen 3.109 N/A ARG 62.A N LYS 58.A O no hydrogen 2.867 N/A ARG 62.A NE GLU 307.A OE1 no hydrogen 2.743 N/A ARG 62.A NE GLU 307.A OE2 no hydrogen 3.404 N/A ARG 62.A NH2 GLU 307.A OE2 no hydrogen 2.707 N/A GLU 63.A N ARG 59.A O no hydrogen 2.911 N/A LEU 64.A N THR 60.A O no hydrogen 3.123 N/A ARG 65.A N TYR 61.A O no hydrogen 2.979 N/A ARG 65.A NH1 TYR 61.A OH no hydrogen 3.194 N/A ARG 65.A NH2 ASP 303.A O no hydrogen 3.162 N/A LEU 66.A N ARG 62.A O no hydrogen 3.128 N/A LEU 67.A N GLU 63.A O no hydrogen 3.038 N/A LYS 68.A N LEU 64.A O no hydrogen 2.875 N/A LYS 68.A NZ GLU 323.A O no hydrogen 2.651 N/A LYS 68.A NZ GLU 323.A OE1 no hydrogen 2.691 N/A HIS 69.A N ARG 65.A O no hydrogen 3.040 N/A HIS 69.A N LEU 66.A O no hydrogen 3.093 N/A HIS 69.A NE2 ASP 300.A O no hydrogen 2.930 N/A MET 70.A N LEU 66.A O no hydrogen 3.155 N/A LYS 71.A N TYR 132.A OH no hydrogen 2.925 N/A ASN 74.A N HIS 72.A ND1 no hydrogen 2.959 N/A ASN 74.A ND2 GLN 125.A OE1 no hydrogen 3.339 N/A ASN 74.A ND2 LEU 156.A O no hydrogen 2.844 N/A VAL 75.A N HIS 72.A O no hydrogen 3.229 N/A ILE 76.A N ILE 158.A O no hydrogen 3.040 N/A LEU 79.A N VAL 97.A O no hydrogen 2.816 N/A ASP 80.A N VAL 97.A O no hydrogen 3.313 N/A PHE 82.A N TYR 95.A O no hydrogen 3.030 N/A THR 83.A OG1 ASP 93.A O no hydrogen 2.915 N/A ALA 85.A N THR 83.A OG1 no hydrogen 3.037 N/A ARG 86.A N GLU 90.A OE1 no hydrogen 2.653 N/A GLU 90.A N SER 87.A OG no hydrogen 3.206 N/A PHE 91.A N LEU 88.A O no hydrogen 3.018 N/A TYR 95.A N PHE 82.A O no hydrogen 2.979 N/A LEU 96.A N LYS 45.A O no hydrogen 2.796 N/A VAL 97.A N ASP 80.A O no hydrogen 2.714 N/A THR 98.A N ALA 43.A O no hydrogen 2.846 N/A THR 98.A OG1 HIS 99.A O no hydrogen 3.543 N/A LEU 100.A N ARG 41.A O no hydrogen 3.378 N/A ALA 103.A N VAL 150.A O no hydrogen 3.241 N/A LEU 105.A N PRO 145.A O no hydrogen 3.280 N/A LEU 105.A N LEU 148.A O no hydrogen 3.149 N/A ASN 107.A N ASP 104.A OD2 no hydrogen 2.795 N/A ILE 108.A N ASP 104.A O no hydrogen 3.104 N/A VAL 109.A N LEU 105.A O no hydrogen 3.027 N/A LYS 110.A N ASN 106.A O no hydrogen 3.050 N/A LYS 110.A NZ ASN 106.A OD1 no hydrogen 3.170 N/A CYS 111.A N ILE 108.A O no hydrogen 2.856 N/A CYS 111.A SG ASN 107.A O no hydrogen 3.231 N/A CYS 111.A SG ILE 108.A O no hydrogen 3.377 N/A HIS 118.A N THR 115.A OG1 no hydrogen 3.112 N/A VAL 119.A N THR 115.A O no hydrogen 2.955 N/A GLN 120.A N ASP 116.A O no hydrogen 2.888 N/A GLN 120.A NE2 ASP 116.A OD2 no hydrogen 2.944 N/A PHE 121.A N ASP 117.A O no hydrogen 3.162 N/A LEU 122.A N HIS 118.A O no hydrogen 3.022 N/A ILE 123.A N VAL 119.A O no hydrogen 2.843 N/A TYR 124.A N GLN 120.A O no hydrogen 2.845 N/A TYR 124.A OH GLU 296.A OE1 no hydrogen 2.478 N/A GLN 125.A N PHE 121.A O no hydrogen 2.993 N/A GLN 125.A NE2 PHE 121.A O no hydrogen 3.380 N/A GLN 125.A NE2 CYS 154.A O no hydrogen 3.023 N/A ILE 126.A N LEU 122.A O no hydrogen 3.050 N/A LEU 127.A N ILE 123.A O no hydrogen 3.044 N/A ARG 128.A N TYR 124.A O no hydrogen 2.904 N/A ARG 128.A NE ASP 295.A O no hydrogen 2.843 N/A ARG 128.A NH1 GLU 73.A OE2 no hydrogen 3.068 N/A ARG 128.A NH1 ASN 74.A OD1 no hydrogen 3.017 N/A ARG 128.A NH2 ASP 295.A O no hydrogen 2.712 N/A GLY 129.A N GLN 125.A O no hydrogen 3.010 N/A LEU 130.A N ILE 126.A O no hydrogen 2.722 N/A LYS 131.A N LEU 127.A O no hydrogen 2.813 N/A LYS 131.A NZ GLU 296.A O no hydrogen 2.820 N/A TYR 132.A N ARG 128.A O no hydrogen 3.483 N/A TYR 132.A OH HIS 69.A O no hydrogen 3.237 N/A ILE 133.A N GLY 129.A O no hydrogen 3.026 N/A HIS 134.A N LEU 130.A O no hydrogen 2.873 N/A HIS 134.A NE2 ASP 184.A OD1 no hydrogen 2.924 N/A SER 135.A N LYS 131.A O no hydrogen 2.852 N/A SER 135.A OG LYS 131.A O no hydrogen 3.395 N/A SER 135.A OG TYR 132.A O no hydrogen 2.484 N/A ALA 136.A N ILE 133.A O no hydrogen 3.089 N/A ASP 137.A N HIS 134.A O no hydrogen 2.953 N/A ILE 138.A N ILE 133.A O no hydrogen 3.236 N/A HIS 140.A N ASP 184.A OD1 no hydrogen 2.770 N/A HIS 140.A NE2 LEU 159.A O no hydrogen 2.654 N/A ARG 141.A N ASP 184.A OD2 no hydrogen 2.787 N/A ARG 141.A NH1 TYR 179.A OH no hydrogen 3.510 N/A ASP 142.A N HIS 140.A ND1 no hydrogen 3.246 N/A ASN 147.A N LYS 144.A O no hydrogen 2.864 N/A ASN 147.A ND2 ASP 142.A O no hydrogen 2.526 N/A LEU 148.A N PRO 145.A O no hydrogen 3.191 N/A ALA 149.A N LYS 157.A O no hydrogen 2.983 N/A VAL 150.A N ALA 103.A O no hydrogen 2.867 N/A ASN 151.A N GLU 155.A O no hydrogen 3.038 N/A ASN 151.A ND2 GLU 155.A OE2 no hydrogen 2.719 N/A CYS 154.A N ASN 151.A O no hydrogen 2.678 N/A CYS 154.A SG HIS 118.A NE2 no hydrogen 2.557 N/A GLU 155.A N ASN 151.A OD1 no hydrogen 2.898 N/A LEU 156.A N GLN 125.A OE1 no hydrogen 2.944 N/A LYS 157.A N ALA 149.A O no hydrogen 2.936 N/A LYS 157.A NZ GLU 73.A O no hydrogen 2.697 N/A ILE 158.A N ASN 74.A O no hydrogen 2.908 N/A LEU 159.A N ASN 147.A O no hydrogen 2.834 N/A THR 164.A OG1 ASP 142.A OD2 no hydrogen 3.065 N/A TRP 166.A N ALA 163.A O no hydrogen 3.318 N/A TRP 166.A NE1 GLY 204.A O no hydrogen 2.999 N/A TYR 167.A N THR 164.A O no hydrogen 2.971 N/A TYR 167.A OH GLU 194.A OE1 no hydrogen 2.557 N/A ARG 168.A N ARG 165.A O no hydrogen 3.269 N/A ARG 168.A NE ARG 141.A O no hydrogen 3.429 N/A ARG 168.A NH2 ARG 141.A O no hydrogen 2.906 N/A GLU 171.A N GLU 171.A OE2 no hydrogen 2.932 N/A MET 173.A N ALA 169.A O no hydrogen 3.099 N/A LEU 174.A N PRO 170.A O no hydrogen 2.886 N/A ASN 175.A N ILE 172.A O no hydrogen 3.030 N/A TRP 176.A N GLU 171.A O no hydrogen 2.865 N/A GLN 181.A NE2 HIS 134.A O no hydrogen 2.841 N/A THR 182.A N ASN 180.A OD1 no hydrogen 2.805 N/A THR 182.A OG1 ASN 180.A OD1 no hydrogen 2.397 N/A THR 182.A OG1 SER 272.A O no hydrogen 3.445 N/A VAL 183.A N ASN 180.A O no hydrogen 3.134 N/A ASP 184.A N GLN 181.A O no hydrogen 2.974 N/A TRP 186.A N THR 182.A O no hydrogen 3.158 N/A SER 187.A N VAL 183.A O no hydrogen 3.231 N/A SER 187.A OG TYR 167.A O no hydrogen 2.839 N/A SER 187.A OG VAL 183.A O no hydrogen 3.204 N/A VAL 188.A N ASP 184.A O no hydrogen 2.901 N/A GLY 189.A N ILE 185.A O no hydrogen 2.925 N/A CYS 190.A N TRP 186.A O no hydrogen 3.050 N/A CYS 190.A SG TRP 166.A O no hydrogen 3.941 N/A CYS 190.A SG TRP 186.A O no hydrogen 3.681 N/A ILE 191.A N SER 187.A O no hydrogen 2.844 N/A MET 192.A N VAL 188.A O no hydrogen 2.756 N/A ALA 193.A N GLY 189.A O no hydrogen 3.029 N/A GLU 194.A N CYS 190.A O no hydrogen 3.245 N/A LEU 195.A N ILE 191.A O no hydrogen 2.947 N/A LEU 196.A N MET 192.A O no hydrogen 3.001 N/A THR 197.A N ALA 193.A O no hydrogen 2.976 N/A THR 197.A N GLU 194.A O no hydrogen 3.378 N/A THR 197.A OG1 ALA 193.A O no hydrogen 3.069 N/A GLY 198.A N GLU 194.A O no hydrogen 2.711 N/A ARG 199.A N THR 197.A OG1 no hydrogen 3.052 N/A GLY 204.A N PHE 202.A O no hydrogen 2.882 N/A GLY 204.A N GLN 210.A OE1 no hydrogen 2.908 N/A THR 205.A N ASP 209.A OD1 no hydrogen 2.801 N/A ASP 209.A N ASP 206.A OD2 no hydrogen 2.786 N/A GLN 210.A N ASP 206.A O no hydrogen 2.915 N/A GLN 210.A NE2 PHE 202.A O no hydrogen 2.913 N/A LEU 211.A N HIS 207.A O no hydrogen 3.203 N/A LYS 212.A N ILE 208.A O no hydrogen 2.985 N/A LEU 213.A N ASP 209.A O no hydrogen 2.809 N/A ILE 214.A N GLN 210.A O no hydrogen 3.097 N/A LEU 215.A N LEU 211.A O no hydrogen 2.910 N/A ARG 216.A N LYS 212.A O no hydrogen 2.986 N/A LEU 217.A N ILE 214.A O no hydrogen 3.118 N/A VAL 218.A N ILE 214.A O no hydrogen 3.083 N/A GLY 219.A N LEU 215.A O no hydrogen 2.800 N/A THR 220.A N MET 244.A O no hydrogen 2.866 N/A THR 220.A OG1 MET 244.A O no hydrogen 3.151 N/A LEU 225.A N GLY 222.A O no hydrogen 3.230 N/A LEU 226.A N GLY 222.A O no hydrogen 3.033 N/A LYS 227.A N ALA 223.A O no hydrogen 3.014 N/A LYS 228.A N LEU 225.A O no hydrogen 2.898 N/A LYS 228.A NZ ASP 271.A OD1 no hydrogen 3.292 N/A LYS 228.A NZ ASP 271.A OD2 no hydrogen 2.732 N/A LYS 228.A NZ ASP 273.A OD1 no hydrogen 2.605 N/A ILE 229.A N LEU 226.A O no hydrogen 3.143 N/A ARG 235.A N CYS 231.A O no hydrogen 3.056 N/A ARG 235.A NE ILE 229.A O no hydrogen 3.193 N/A ARG 235.A NH2 ILE 229.A O no hydrogen 3.232 N/A ASN 236.A N GLU 232.A O no hydrogen 2.645 N/A TYR 237.A N SER 233.A O no hydrogen 2.912 N/A ILE 238.A N ALA 234.A O no hydrogen 2.962 N/A GLN 239.A N ARG 235.A O no hydrogen 3.023 N/A SER 240.A N ASN 236.A O no hydrogen 2.968 N/A SER 240.A OG ASN 236.A O no hydrogen 3.144 N/A LEU 241.A N ILE 238.A O no hydrogen 3.120 N/A MET 244.A N THR 220.A OG1 no hydrogen 2.686 N/A LYS 246.A NZ MET 247.A O no hydrogen 3.238 N/A LYS 246.A NZ GLU 265.A OE1 no hydrogen 3.428 N/A LYS 246.A NZ GLU 265.A OE2 no hydrogen 2.621 N/A MET 247.A N LEU 217.A O no hydrogen 2.982 N/A PHE 249.A N GLU 265.A OE1 no hydrogen 3.115 N/A ALA 250.A N ASN 248.A OD1 no hydrogen 2.974 N/A ASN 251.A N ASN 248.A O no hydrogen 2.825 N/A VAL 252.A N PHE 249.A O no hydrogen 2.807 N/A PHE 253.A N PHE 249.A O no hydrogen 2.912 N/A ALA 256.A N PHE 253.A O no hydrogen 3.385 N/A ASN 257.A ND2 ASP 116.A OD2 no hydrogen 2.814 N/A LEU 259.A N ASN 257.A OD1 no hydrogen 2.852 N/A VAL 261.A N ASN 257.A O no hydrogen 3.018 N/A ASP 262.A N PRO 258.A O no hydrogen 3.013 N/A LEU 263.A N LEU 259.A O no hydrogen 3.038 N/A LEU 264.A N ALA 260.A O no hydrogen 2.897 N/A GLU 265.A N VAL 261.A O no hydrogen 2.914 N/A LYS 266.A N ASP 262.A O no hydrogen 3.233 N/A LYS 266.A N LEU 263.A O no hydrogen 2.911 N/A LYS 266.A NZ ASP 262.A OD1 no hydrogen 3.404 N/A LYS 266.A NZ ASP 262.A OD2 no hydrogen 3.174 N/A MET 267.A N LEU 263.A O no hydrogen 3.017 N/A MET 267.A N LEU 264.A O no hydrogen 3.099 N/A LEU 268.A N LEU 264.A O no hydrogen 2.856 N/A ASP 273.A N ASP 271.A OD1 no hydrogen 3.020 N/A LYS 274.A N ASP 271.A O no hydrogen 2.805 N/A ARG 275.A N SER 272.A O no hydrogen 3.200 N/A ARG 275.A NE VAL 269.A O no hydrogen 2.959 N/A ARG 275.A NH1 GLU 171.A OE1 no hydrogen 2.752 N/A ARG 275.A NH1 THR 182.A O no hydrogen 3.015 N/A ARG 275.A NH2 GLU 171.A OE1 no hydrogen 3.540 N/A ARG 275.A NH2 GLU 171.A OE2 no hydrogen 2.842 N/A ARG 275.A NH2 VAL 269.A O no hydrogen 3.015 N/A ILE 276.A N LYS 266.A O no hydrogen 3.159 N/A THR 277.A N GLN 280.A OE1 no hydrogen 3.129 N/A GLN 280.A N THR 277.A OG1 no hydrogen 3.081 N/A ALA 281.A N THR 277.A O no hydrogen 2.895 N/A LEU 282.A N ALA 278.A O no hydrogen 2.984 N/A ALA 283.A N GLN 280.A O no hydrogen 3.162 N/A HIS 284.A N ALA 281.A O no hydrogen 3.046 N/A HIS 284.A NE2 ASP 262.A OD2 no hydrogen 2.734 N/A TYR 286.A N HIS 284.A ND1 no hydrogen 3.146 N/A TYR 286.A OH ASP 116.A OD1 no hydrogen 2.724 N/A PHE 287.A N HIS 284.A O no hydrogen 3.083 N/A ALA 288.A N ALA 285.A O no hydrogen 2.869 N/A TYR 290.A N PHE 287.A O no hydrogen 2.882 N/A HIS 291.A N PHE 287.A O no hydrogen 2.750 N/A HIS 291.A ND1 GLU 296.A OE1 no hydrogen 2.904 N/A ASP 292.A N GLU 296.A OE1 no hydrogen 3.262 N/A ASP 294.A N ASP 292.A OD1 no hydrogen 2.982 N/A ASP 295.A N ASP 292.A O no hydrogen 2.941 N/A ALA 299.A N SER 135.A OG no hydrogen 2.867 N/A GLN 304.A NE2 ASP 137.A O no hydrogen 2.885 N/A SER 305.A N ASP 303.A OD1 no hydrogen 2.839 N/A SER 305.A OG ASP 303.A OD1 no hydrogen 2.662 N/A GLU 307.A N GLN 304.A O no hydrogen 3.006 N/A SER 308.A N SER 305.A O no hydrogen 3.188 N/A SER 308.A OG SER 305.A O no hydrogen 2.936 N/A ARG 309.A N PHE 306.A O no hydrogen 2.888 N/A LEU 312.A N GLU 315.A OE1 no hydrogen 2.917 N/A TRP 316.A N LEU 312.A O no hydrogen 2.925 N/A LYS 317.A N ILE 313.A O no hydrogen 2.863 N/A LYS 317.A NZ PHE 91.A O no hydrogen 2.795 N/A SER 318.A N ASP 314.A O no hydrogen 2.937 N/A LEU 319.A N GLU 315.A O no hydrogen 3.063 N/A THR 320.A N TRP 316.A O no hydrogen 2.980 N/A THR 320.A OG1 TRP 316.A O no hydrogen 2.967 N/A TYR 321.A N LYS 317.A O no hydrogen 2.895 N/A ASP 322.A N SER 318.A O no hydrogen 2.901 N/A GLU 323.A N LEU 319.A O no hydrogen 3.094 N/A VAL 324.A N THR 320.A O no hydrogen 2.963 N/A ILE 325.A N TYR 321.A O no hydrogen 2.947 N/A SER 326.A N ASP 322.A O no hydrogen 2.983 N/A SER 326.A OG ASP 322.A O no hydrogen 3.081 N/A SER 326.A OG GLU 323.A O no hydrogen 3.406 N/A PHE 327.A N VAL 324.A O no hydrogen 3.117 N/A