Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5r9d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A NH2 PRO 85.A O no hydrogen 2.858 N/A TYR 5.A N VAL 16.A O no hydrogen 2.929 N/A TYR 5.A OH TYR 20.A O no hydrogen 2.691 N/A GLN 7.A N TRP 14.A O no hydrogen 2.942 N/A LEU 9.A N THR 12.A O no hydrogen 2.820 N/A THR 12.A N LEU 9.A O no hydrogen 3.288 N/A THR 12.A OG1 ASN 10.A O no hydrogen 3.410 N/A TRP 14.A N GLN 7.A O no hydrogen 2.705 N/A GLU 15.A N TYR 96.A OH no hydrogen 3.090 N/A VAL 16.A N TYR 5.A O no hydrogen 3.063 N/A GLU 18.A N THR 3.A O no hydrogen 2.954 N/A ARG 19.A NE ASP 36.A OD1 no hydrogen 2.918 N/A ARG 19.A NH2 ASP 36.A OD1 no hydrogen 3.554 N/A ARG 19.A NH2 ASP 36.A OD2 no hydrogen 2.980 N/A TYR 20.A N PRO 17.A O no hydrogen 3.116 N/A TYR 20.A OH ASP 81.A OD2 no hydrogen 2.745 N/A GLN 21.A N PHE 35.A O no hydrogen 2.988 N/A GLN 21.A NE2 GLU 18.A O no hydrogen 2.970 N/A SER 24.A N ALA 33.A O no hydrogen 2.908 N/A VAL 26.A N VAL 31.A O no hydrogen 2.900 N/A GLY 27.A N VAL 31.A O no hydrogen 3.395 N/A SER 30.A N LYS 47.A O no hydrogen 3.285 N/A VAL 31.A N GLY 27.A O no hydrogen 2.844 N/A CYS 32.A N VAL 45.A O no hydrogen 2.908 N/A ALA 33.A N SER 24.A O no hydrogen 2.834 N/A ALA 34.A N VAL 43.A O no hydrogen 2.977 N/A PHE 35.A N GLN 21.A O no hydrogen 2.898 N/A ASP 36.A N HIS 41.A O no hydrogen 2.960 N/A THR 37.A N ARG 19.A O no hydrogen 2.983 N/A THR 37.A OG1 ARG 19.A O no hydrogen 3.092 N/A LYS 38.A N ASP 36.A OD1 no hydrogen 2.981 N/A THR 39.A N ASP 36.A OD2 no hydrogen 3.377 N/A THR 39.A OG1 ASP 36.A OD2 no hydrogen 2.659 N/A GLY 40.A N ASP 36.A O no hydrogen 2.747 N/A HIS 41.A N THR 39.A OG1 no hydrogen 3.182 N/A VAL 43.A N ALA 34.A O no hydrogen 2.904 N/A ALA 44.A N THR 99.A O no hydrogen 2.825 N/A VAL 45.A N CYS 32.A O no hydrogen 2.831 N/A LYS 46.A N LEU 97.A O no hydrogen 2.853 N/A LYS 46.A NZ GLU 64.A OE2 no hydrogen 2.707 N/A LYS 47.A N SER 30.A O no hydrogen 3.018 N/A LYS 47.A NZ ILE 13.A O no hydrogen 2.703 N/A LEU 48.A N VAL 95.A O no hydrogen 3.106 N/A GLN 53.A N ARG 50.A O no hydrogen 3.446 N/A SER 54.A OG HIS 57.A ND1 no hydrogen 2.854 N/A HIS 57.A N SER 54.A OG no hydrogen 3.096 N/A HIS 57.A ND1 SER 54.A OG no hydrogen 2.854 N/A ALA 58.A N SER 54.A O no hydrogen 2.821 N/A LYS 59.A N ILE 55.A O no hydrogen 2.944 N/A LYS 59.A NZ GLU 320.A O no hydrogen 2.650 N/A ARG 60.A N ILE 56.A O no hydrogen 2.975 N/A THR 61.A N HIS 57.A O no hydrogen 2.935 N/A THR 61.A OG1 PRO 51.A O no hydrogen 2.873 N/A THR 61.A OG1 HIS 57.A O no hydrogen 3.143 N/A TYR 62.A N ALA 58.A O no hydrogen 3.116 N/A ARG 63.A N LYS 59.A O no hydrogen 2.907 N/A ARG 63.A NE GLU 320.A OE1 no hydrogen 3.468 N/A ARG 63.A NE GLU 320.A OE2 no hydrogen 2.770 N/A ARG 63.A NH2 GLU 320.A OE1 no hydrogen 2.872 N/A GLU 64.A N ARG 60.A O no hydrogen 3.035 N/A LEU 65.A N THR 61.A O no hydrogen 3.124 N/A ARG 66.A N TYR 62.A O no hydrogen 2.932 N/A ARG 66.A NH1 TYR 62.A OH no hydrogen 3.102 N/A ARG 66.A NH2 ASP 316.A O no hydrogen 2.894 N/A LEU 67.A N ARG 63.A O no hydrogen 3.047 N/A LEU 68.A N GLU 64.A O no hydrogen 2.969 N/A LYS 69.A N LEU 65.A O no hydrogen 2.946 N/A LYS 69.A NZ GLU 336.A O no hydrogen 2.886 N/A LYS 69.A NZ GLU 336.A OE1 no hydrogen 2.754 N/A HIS 70.A N ARG 66.A O no hydrogen 3.291 N/A HIS 70.A N LEU 67.A O no hydrogen 3.094 N/A HIS 70.A NE2 ASP 313.A O no hydrogen 2.885 N/A LYS 72.A N TYR 132.A OH no hydrogen 2.937 N/A ASN 75.A N HIS 73.A ND1 no hydrogen 2.957 N/A ASN 75.A ND2 LEU 156.A O no hydrogen 3.114 N/A VAL 76.A N HIS 73.A O no hydrogen 3.172 N/A ILE 77.A N ILE 158.A O no hydrogen 2.933 N/A LEU 80.A N VAL 98.A O no hydrogen 2.866 N/A PHE 83.A N TYR 96.A O no hydrogen 3.067 N/A THR 84.A OG1 ASP 94.A O no hydrogen 2.889 N/A ALA 86.A N THR 84.A OG1 no hydrogen 3.259 N/A ARG 87.A N GLU 91.A OE2 no hydrogen 2.809 N/A SER 88.A OG GLU 90.A OE1 no hydrogen 3.279 N/A GLU 91.A N SER 88.A O no hydrogen 3.337 N/A PHE 92.A N LEU 89.A O no hydrogen 3.280 N/A TYR 96.A N PHE 83.A O no hydrogen 3.052 N/A LEU 97.A N LYS 46.A O no hydrogen 2.927 N/A VAL 98.A N ASP 81.A O no hydrogen 2.965 N/A THR 99.A N ALA 44.A O no hydrogen 3.087 N/A THR 99.A OG1 GLY 78.A O no hydrogen 2.708 N/A LEU 101.A N ARG 42.A O no hydrogen 3.082 N/A ASP 104.A N ASN 107.A OD1 no hydrogen 3.273 N/A LEU 105.A N LEU 148.A O no hydrogen 2.927 N/A ASN 107.A N ASP 104.A O no hydrogen 3.150 N/A ASN 107.A N ASP 104.A OD1 no hydrogen 2.982 N/A VAL 109.A N LEU 105.A O no hydrogen 2.952 N/A LYS 110.A N ASN 106.A O no hydrogen 3.245 N/A CYS 111.A N ASN 107.A O no hydrogen 3.035 N/A CYS 111.A SG ASN 107.A O no hydrogen 3.143 N/A THR 115.A N HIS 118.A ND1 no hydrogen 3.146 N/A THR 115.A OG1 HIS 118.A ND1 no hydrogen 3.018 N/A HIS 118.A N THR 115.A OG1 no hydrogen 3.195 N/A VAL 119.A N THR 115.A O no hydrogen 3.183 N/A GLN 120.A N ASP 116.A O no hydrogen 2.904 N/A GLN 120.A NE2 ASP 116.A OD2 no hydrogen 3.131 N/A PHE 121.A N ASP 117.A O no hydrogen 3.106 N/A LEU 122.A N HIS 118.A O no hydrogen 2.969 N/A ILE 123.A N VAL 119.A O no hydrogen 2.953 N/A TYR 124.A N GLN 120.A O no hydrogen 2.933 N/A TYR 124.A OH GLU 309.A OE2 no hydrogen 2.767 N/A GLN 125.A N PHE 121.A O no hydrogen 3.158 N/A GLN 125.A NE2 PHE 121.A O no hydrogen 3.204 N/A GLN 125.A NE2 CYS 154.A O no hydrogen 2.906 N/A ILE 126.A N LEU 122.A O no hydrogen 3.165 N/A LEU 127.A N ILE 123.A O no hydrogen 3.005 N/A ARG 128.A N TYR 124.A O no hydrogen 2.880 N/A ARG 128.A NE ASP 308.A O no hydrogen 2.882 N/A ARG 128.A NH1 GLU 74.A OE1 no hydrogen 3.059 N/A ARG 128.A NH1 ASN 75.A OD1 no hydrogen 2.909 N/A ARG 128.A NH2 GLU 74.A OE1 no hydrogen 3.495 N/A ARG 128.A NH2 ASP 308.A O no hydrogen 3.034 N/A ARG 128.A NH2 ASP 308.A OD1 no hydrogen 3.251 N/A GLY 129.A N GLN 125.A O no hydrogen 3.001 N/A LEU 130.A N ILE 126.A O no hydrogen 2.854 N/A LYS 131.A N LEU 127.A O no hydrogen 2.859 N/A LYS 131.A NZ GLU 309.A O no hydrogen 2.796 N/A TYR 132.A N ARG 128.A O no hydrogen 3.453 N/A TYR 132.A OH HIS 70.A O no hydrogen 3.405 N/A ILE 133.A N GLY 129.A O no hydrogen 2.988 N/A HIS 134.A N LEU 130.A O no hydrogen 2.801 N/A HIS 134.A NE2 ASP 197.A OD2 no hydrogen 2.898 N/A SER 135.A N LYS 131.A O no hydrogen 3.033 N/A SER 135.A OG TYR 132.A O no hydrogen 2.729 N/A ALA 136.A N ILE 133.A O no hydrogen 3.179 N/A ASP 137.A N HIS 134.A O no hydrogen 2.911 N/A ILE 138.A N ILE 133.A O no hydrogen 3.392 N/A HIS 140.A N ASP 197.A OD2 no hydrogen 2.916 N/A HIS 140.A NE2 LEU 159.A O no hydrogen 2.907 N/A ARG 141.A N ASP 197.A OD1 no hydrogen 2.953 N/A ARG 141.A NE TYR 192.A OH no hydrogen 3.020 N/A ASP 142.A N HIS 140.A ND1 no hydrogen 3.026 N/A ASN 147.A N LYS 144.A O no hydrogen 2.905 N/A ASN 147.A ND2 ASP 142.A O no hydrogen 3.002 N/A LEU 148.A N PRO 145.A O no hydrogen 3.259 N/A ALA 149.A N LYS 157.A O no hydrogen 2.931 N/A VAL 150.A N ALA 103.A O no hydrogen 2.964 N/A ASN 151.A N GLU 155.A O no hydrogen 3.070 N/A ASN 151.A ND2 GLU 155.A OE2 no hydrogen 2.803 N/A ASP 153.A N ASN 151.A OD1 no hydrogen 2.824 N/A CYS 154.A N ASN 151.A O no hydrogen 3.083 N/A GLU 155.A N ASN 151.A OD1 no hydrogen 3.019 N/A LEU 156.A N GLN 125.A OE1 no hydrogen 2.941 N/A LYS 157.A N ALA 149.A O no hydrogen 2.929 N/A LYS 157.A NZ GLU 74.A O no hydrogen 2.854 N/A ILE 158.A N ASN 75.A O no hydrogen 2.903 N/A LEU 159.A N ASN 147.A O no hydrogen 3.139 N/A GLY 162.A N HIS 140.A O no hydrogen 2.815 N/A MET 171.A N ASP 168.A O no hydrogen 3.180 N/A THR 172.A N ASP 169.A O no hydrogen 3.265 N/A THR 172.A OG1 ASP 168.A O no hydrogen 2.828 N/A THR 177.A OG1 GLU 170.A O no hydrogen 2.659 N/A ARG 178.A N VAL 175.A O no hydrogen 3.206 N/A ARG 178.A NE GLN 223.A OE1 no hydrogen 2.865 N/A ARG 178.A NH1 MET 171.A O no hydrogen 2.852 N/A ARG 178.A NH1 GLY 173.A O no hydrogen 2.787 N/A ARG 178.A NH2 GLY 173.A O no hydrogen 3.112 N/A ARG 178.A NH2 GLY 217.A O no hydrogen 3.037 N/A ARG 178.A NH2 GLN 223.A OE1 no hydrogen 3.092 N/A TRP 179.A NE1 GLY 217.A O no hydrogen 3.166 N/A TYR 180.A OH GLU 207.A OE1 no hydrogen 2.614 N/A ARG 181.A N ARG 178.A O no hydrogen 3.205 N/A ARG 181.A NH2 ASP 142.A OD1 no hydrogen 3.013 N/A GLU 184.A N GLU 184.A OE1 no hydrogen 2.835 N/A ILE 185.A N ALA 182.A O no hydrogen 3.222 N/A MET 186.A N ALA 182.A O no hydrogen 3.057 N/A ASN 188.A N ILE 185.A O no hydrogen 3.298 N/A TRP 189.A N GLU 184.A O no hydrogen 2.712 N/A THR 195.A N ASN 193.A OD1 no hydrogen 3.208 N/A THR 195.A OG1 ASN 193.A OD1 no hydrogen 2.689 N/A VAL 196.A N ASN 193.A O no hydrogen 3.149 N/A ASP 197.A N GLN 194.A O no hydrogen 3.090 N/A ILE 198.A N THR 195.A O no hydrogen 3.140 N/A TRP 199.A N THR 195.A O no hydrogen 3.420 N/A SER 200.A N VAL 196.A O no hydrogen 3.339 N/A SER 200.A OG TYR 180.A O no hydrogen 2.831 N/A SER 200.A OG VAL 196.A O no hydrogen 3.391 N/A VAL 201.A N ASP 197.A O no hydrogen 3.038 N/A GLY 202.A N ILE 198.A O no hydrogen 3.017 N/A CYS 203.A N TRP 199.A O no hydrogen 3.071 N/A CYS 203.A SG TRP 199.A O no hydrogen 3.621 N/A ILE 204.A N SER 200.A O no hydrogen 3.005 N/A MET 205.A N VAL 201.A O no hydrogen 2.846 N/A ALA 206.A N GLY 202.A O no hydrogen 3.042 N/A GLU 207.A N CYS 203.A O no hydrogen 3.245 N/A LEU 208.A N ILE 204.A O no hydrogen 2.987 N/A LEU 209.A N MET 205.A O no hydrogen 3.115 N/A THR 210.A N ALA 206.A O no hydrogen 3.034 N/A THR 210.A OG1 ALA 206.A O no hydrogen 3.255 N/A GLY 211.A N GLU 207.A O no hydrogen 2.826 N/A ARG 212.A N THR 210.A OG1 no hydrogen 3.070 N/A GLY 217.A N PHE 215.A O no hydrogen 2.893 N/A THR 218.A N ASP 222.A OD2 no hydrogen 2.928 N/A THR 218.A OG1 ASP 219.A OD2 no hydrogen 3.444 N/A ILE 221.A N ASP 219.A OD1 no hydrogen 2.963 N/A ASP 222.A N ASP 219.A OD1 no hydrogen 2.953 N/A GLN 223.A N ASP 219.A O no hydrogen 2.948 N/A GLN 223.A NE2 ARG 178.A O no hydrogen 2.986 N/A LEU 224.A N HIS 220.A O no hydrogen 3.050 N/A LYS 225.A N ILE 221.A O no hydrogen 3.017 N/A LEU 226.A N ASP 222.A O no hydrogen 3.039 N/A ILE 227.A N GLN 223.A O no hydrogen 2.970 N/A LEU 228.A N LEU 224.A O no hydrogen 2.913 N/A ARG 229.A N LYS 225.A O no hydrogen 3.075 N/A LEU 230.A N ILE 227.A O no hydrogen 3.103 N/A VAL 231.A N ILE 227.A O no hydrogen 3.011 N/A GLY 232.A N LEU 228.A O no hydrogen 2.826 N/A THR 233.A N MET 257.A O no hydrogen 3.101 N/A THR 233.A OG1 MET 257.A O no hydrogen 3.387 N/A LEU 239.A N GLY 235.A O no hydrogen 3.070 N/A LYS 240.A N ALA 236.A O no hydrogen 3.100 N/A LYS 241.A N LEU 238.A O no hydrogen 3.017 N/A LYS 241.A NZ ASP 284.A OD1 no hydrogen 3.253 N/A LYS 241.A NZ ASP 284.A OD2 no hydrogen 2.952 N/A LYS 241.A NZ ASP 286.A OD2 no hydrogen 2.574 N/A ILE 242.A N LEU 239.A O no hydrogen 3.061 N/A ALA 247.A N SER 244.A OG no hydrogen 3.298 N/A ARG 248.A N SER 244.A O no hydrogen 3.088 N/A ARG 248.A NH1 ILE 242.A O no hydrogen 2.728 N/A ARG 248.A NH1 SER 243.A O no hydrogen 3.489 N/A ASN 249.A N GLU 245.A O no hydrogen 2.767 N/A TYR 250.A N SER 246.A O no hydrogen 3.108 N/A ILE 251.A N ALA 247.A O no hydrogen 3.119 N/A GLN 252.A N ARG 248.A O no hydrogen 3.235 N/A SER 253.A N TYR 250.A O no hydrogen 2.971 N/A SER 253.A OG TYR 250.A O no hydrogen 2.506 N/A LEU 254.A N ILE 251.A O no hydrogen 3.071 N/A MET 257.A N THR 233.A OG1 no hydrogen 3.111 N/A LYS 259.A NZ MET 260.A O no hydrogen 2.842 N/A LYS 259.A NZ GLU 278.A OE2 no hydrogen 3.299 N/A MET 260.A N LEU 230.A O no hydrogen 2.966 N/A ALA 263.A N ASN 261.A OD1 no hydrogen 2.898 N/A ASN 264.A N ASN 261.A O no hydrogen 3.061 N/A VAL 265.A N PHE 262.A O no hydrogen 3.185 N/A PHE 266.A N PHE 262.A O no hydrogen 2.935 N/A ALA 269.A N PHE 266.A O no hydrogen 3.186 N/A ASN 270.A ND2 ASP 116.A OD2 no hydrogen 2.867 N/A LEU 272.A N ASN 270.A OD1 no hydrogen 2.944 N/A VAL 274.A N ASN 270.A O no hydrogen 3.098 N/A ASP 275.A N PRO 271.A O no hydrogen 3.021 N/A LEU 276.A N LEU 272.A O no hydrogen 3.115 N/A LEU 277.A N ALA 273.A O no hydrogen 3.009 N/A GLU 278.A N VAL 274.A O no hydrogen 3.029 N/A LYS 279.A N ASP 275.A O no hydrogen 3.273 N/A LYS 279.A N LEU 276.A O no hydrogen 3.016 N/A LYS 279.A NZ ASP 275.A OD1 no hydrogen 3.417 N/A LYS 279.A NZ ASP 275.A OD2 no hydrogen 2.612 N/A MET 280.A N.A LEU 276.A O no hydrogen 3.061 N/A MET 280.A N.A LEU 277.A O no hydrogen 3.231 N/A MET 280.A N.B LEU 276.A O no hydrogen 3.070 N/A MET 280.A N.B LEU 277.A O no hydrogen 3.228 N/A LEU 281.A N LEU 277.A O no hydrogen 2.964 N/A ASP 286.A N ASP 284.A OD1 no hydrogen 3.100 N/A LYS 287.A N ASP 284.A O no hydrogen 2.994 N/A ARG 288.A N SER 285.A O no hydrogen 3.379 N/A ARG 288.A NE VAL 282.A O no hydrogen 2.794 N/A ARG 288.A NH1 GLU 184.A OE2 no hydrogen 2.937 N/A ARG 288.A NH1 THR 195.A O no hydrogen 3.288 N/A ARG 288.A NH2 GLU 184.A OE1 no hydrogen 2.935 N/A ARG 288.A NH2 GLU 184.A OE2 no hydrogen 3.505 N/A ARG 288.A NH2 VAL 282.A O no hydrogen 3.355 N/A ARG 288.A NH2 LEU 283.A O no hydrogen 3.154 N/A ILE 289.A N LYS 279.A O no hydrogen 3.074 N/A THR 290.A N GLN 293.A OE1 no hydrogen 3.032 N/A GLN 293.A N THR 290.A OG1 no hydrogen 3.172 N/A ALA 294.A N THR 290.A O no hydrogen 2.859 N/A LEU 295.A N ALA 291.A O no hydrogen 3.078 N/A ALA 296.A N GLN 293.A O no hydrogen 3.168 N/A HIS 297.A N ALA 294.A O no hydrogen 3.046 N/A HIS 297.A NE2 ASP 275.A OD2 no hydrogen 2.747 N/A TYR 299.A N HIS 297.A ND1 no hydrogen 3.073 N/A TYR 299.A OH ASP 116.A OD1 no hydrogen 2.678 N/A PHE 300.A N HIS 297.A O no hydrogen 3.077 N/A ALA 301.A N ALA 298.A O no hydrogen 3.118 N/A GLN 302.A NE2 ASP 117.A OD1 no hydrogen 3.137 N/A GLN 302.A NE2 GLN 120.A OE1 no hydrogen 2.633 N/A TYR 303.A N PHE 300.A O no hydrogen 2.943 N/A HIS 304.A N PHE 300.A O no hydrogen 2.928 N/A HIS 304.A ND1 GLU 309.A OE2 no hydrogen 2.761 N/A ASP 305.A N GLU 309.A OE2 no hydrogen 3.165 N/A ASP 307.A N ASP 305.A OD1 no hydrogen 3.110 N/A ASP 308.A N ASP 305.A O no hydrogen 2.930 N/A ALA 312.A N SER 135.A OG no hydrogen 2.887 N/A SER 318.A N ASP 316.A OD1 no hydrogen 2.819 N/A SER 318.A OG ASP 316.A OD1 no hydrogen 2.703 N/A GLU 320.A N GLN 317.A O no hydrogen 3.021 N/A SER 321.A N SER 318.A O no hydrogen 3.230 N/A SER 321.A OG SER 318.A O no hydrogen 3.234 N/A ARG 322.A N PHE 319.A O no hydrogen 2.997 N/A LEU 325.A N GLU 328.A OE1 no hydrogen 3.034 N/A GLU 328.A N LEU 325.A O no hydrogen 2.925 N/A TRP 329.A N LEU 325.A O no hydrogen 3.001 N/A LYS 330.A N ILE 326.A O no hydrogen 2.860 N/A LYS 330.A NZ PHE 92.A O no hydrogen 2.836 N/A SER 331.A N ASP 327.A O no hydrogen 3.025 N/A LEU 332.A N GLU 328.A O no hydrogen 3.101 N/A THR 333.A N TRP 329.A O no hydrogen 2.990 N/A THR 333.A OG1 TRP 329.A O no hydrogen 2.953 N/A TYR 334.A N LYS 330.A O no hydrogen 2.923 N/A ASP 335.A N SER 331.A O no hydrogen 3.046 N/A GLU 336.A N LEU 332.A O no hydrogen 3.260 N/A VAL 337.A N THR 333.A O no hydrogen 2.980 N/A ILE 338.A N TYR 334.A O no hydrogen 3.084 N/A SER 339.A N ASP 335.A O no hydrogen 3.182 N/A SER 339.A OG ASP 335.A O no hydrogen 3.064 N/A SER 339.A OG GLU 336.A O no hydrogen 3.540 N/A PHE 340.A N VAL 337.A O no hydrogen 3.318 N/A