Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5t9b_G.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 4.A N ASN 1.A O no hydrogen 3.145 N/A ASP 6.A N SER 4.A OG no hydrogen 3.219 N/A ARG 7.A N SER 4.A O no hydrogen 2.975 N/A LEU 9.A N THR 242.A O no hydrogen 2.980 N/A THR 10.A N ASP 37.A OD2 no hydrogen 2.615 N/A VAL 11.A N VAL 244.A O no hydrogen 3.065 N/A ALA 12.A N PHE 38.A O no hydrogen 2.922 N/A HIS 13.A N THR 246.A O no hydrogen 2.849 N/A HIS 13.A ND1 ASN 247.A OD1 no hydrogen 2.670 N/A ARG 14.A N GLU 40.A OE1 no hydrogen 2.886 N/A ARG 14.A NH1 GLU 22.A OE1 no hydrogen 2.843 N/A ARG 14.A NH1 GLU 22.A OE2 no hydrogen 3.495 N/A GLY 15.A N ALA 12.A O no hydrogen 2.910 N/A ALA 16.A N SER 27.A O no hydrogen 3.048 N/A SER 17.A OG HIS 13.A O no hydrogen 2.737 N/A GLY 18.A N ASN 247.A O no hydrogen 2.907 N/A TYR 19.A N ALA 16.A O no hydrogen 3.020 N/A TYR 19.A OH ASP 250.A OD1 no hydrogen 2.725 N/A VAL 20.A N ALA 16.A O no hydrogen 3.092 N/A HIS 23.A N ARG 14.A O no hydrogen 3.059 N/A HIS 23.A ND1 TYR 28.A OH no hydrogen 2.726 N/A HIS 23.A NE2 ASP 42.A OD2 no hydrogen 2.702 N/A THR 24.A OG1 PRO 21.A O no hydrogen 2.793 N/A SER 27.A N THR 24.A OG1 no hydrogen 3.097 N/A SER 27.A OG ARG 14.A O no hydrogen 2.889 N/A TYR 28.A N THR 24.A O no hydrogen 3.095 N/A TYR 28.A OH HIS 23.A ND1 no hydrogen 2.726 N/A GLU 29.A N ILE 25.A O no hydrogen 2.782 N/A THR 30.A N LEU 26.A O no hydrogen 2.915 N/A THR 30.A OG1 LEU 26.A O no hydrogen 2.869 N/A ALA 31.A N SER 27.A O no hydrogen 3.060 N/A GLN 32.A N TYR 28.A O no hydrogen 2.909 N/A GLN 32.A NE2 HIS 116.A O no hydrogen 2.982 N/A LYS 33.A N GLU 29.A O no hydrogen 2.995 N/A MET 34.A N THR 30.A O no hydrogen 2.917 N/A MET 34.A N ALA 31.A O no hydrogen 3.145 N/A LYS 35.A N GLN 32.A O no hydrogen 2.939 N/A ALA 36.A N ALA 31.A O no hydrogen 3.015 N/A ASP 37.A N THR 10.A O no hydrogen 2.864 N/A PHE 38.A N THR 10.A O no hydrogen 3.022 N/A ILE 39.A N ASN 118.A O no hydrogen 2.899 N/A GLU 40.A N ALA 12.A O no hydrogen 3.101 N/A LEU 41.A N TYR 120.A O no hydrogen 2.830 N/A LEU 43.A N GLU 122.A O no hydrogen 3.348 N/A GLN 44.A N ILE 52.A O no hydrogen 2.959 N/A GLN 44.A NE2 MET 54.A O no hydrogen 3.000 N/A THR 46.A N LYS 50.A O no hydrogen 2.853 N/A THR 46.A OG1 ASP 48.A OD1 no hydrogen 2.625 N/A THR 46.A OG1 LYS 50.A O no hydrogen 3.546 N/A LYS 47.A N HIS 72.A O no hydrogen 2.806 N/A ASP 48.A N ASP 48.A OD1 no hydrogen 2.643 N/A GLY 49.A N THR 46.A O no hydrogen 2.930 N/A LYS 50.A N THR 46.A OG1 no hydrogen 2.950 N/A ILE 52.A N GLN 44.A O no hydrogen 2.977 N/A VAL 53.A N PRO 104.A O no hydrogen 2.987 N/A MET 54.A N ASP 42.A O no hydrogen 2.847 N/A HIS 55.A ND1 ASP 56.A OD1 no hydrogen 2.681 N/A LEU 59.A N GLY 67.A O no hydrogen 2.754 N/A ARG 61.A NE ASP 56.A OD2 no hydrogen 2.782 N/A ARG 61.A NH1 GLU 22.A OE1 no hydrogen 2.996 N/A ARG 61.A NH2 GLU 22.A OE1 no hydrogen 3.426 N/A ARG 61.A NH2 GLU 22.A OE2 no hydrogen 2.817 N/A ARG 61.A NH2 ASP 56.A OD2 no hydrogen 3.568 N/A THR 63.A N LEU 59.A O no hydrogen 3.176 N/A THR 63.A OG1 LEU 59.A O no hydrogen 2.720 N/A ASN 64.A N ASP 81.A O no hydrogen 3.256 N/A GLY 65.A N THR 63.A OG1 no hydrogen 2.841 N/A GLY 67.A N ASP 60.A OD1 no hydrogen 2.844 N/A VAL 69.A N GLU 57.A O no hydrogen 2.850 N/A ASP 71.A N TRP 68.A O no hydrogen 3.032 N/A HIS 72.A N VAL 69.A O no hydrogen 3.033 N/A HIS 72.A ND1 TRP 68.A O no hydrogen 3.005 N/A LEU 74.A N ASP 48.A OD1 no hydrogen 2.961 N/A ASP 76.A N THR 73.A OG1 no hydrogen 3.213 N/A ILE 77.A N THR 73.A O no hydrogen 3.055 N/A LYS 78.A N LEU 74.A O no hydrogen 2.821 N/A LYS 78.A NZ VAL 103.A O no hydrogen 2.715 N/A LYS 78.A NZ GLU 108.A OE1 no hydrogen 2.863 N/A LYS 78.A NZ GLU 108.A OE2 no hydrogen 3.526 N/A LYS 79.A N ASP 76.A O no hydrogen 3.146 N/A LYS 79.A NZ ASP 76.A OD1 no hydrogen 3.007 N/A LEU 80.A N ILE 77.A O no hydrogen 3.065 N/A ASP 81.A N ASN 64.A OD1 no hydrogen 2.761 N/A ALA 82.A N LEU 101.A O no hydrogen 2.644 N/A GLY 83.A N ASP 81.A OD1 no hydrogen 2.899 N/A SER 84.A N ASP 81.A OD1 no hydrogen 3.056 N/A SER 84.A OG ASP 81.A OD2 no hydrogen 2.646 N/A TRP 85.A NE1 ALA 82.A O no hydrogen 3.119 N/A PHE 86.A N GLY 83.A O no hydrogen 3.049 N/A ASN 87.A ND2 LYS 95.A O no hydrogen 2.898 N/A GLU 88.A N SER 84.A O no hydrogen 3.139 N/A ALA 89.A N TRP 85.A O no hydrogen 2.883 N/A TYR 90.A N PHE 86.A O no hydrogen 2.844 N/A GLU 92.A N GLU 92.A OE1 no hydrogen 2.591 N/A LYS 93.A N TYR 90.A O no hydrogen 2.817 N/A LYS 93.A NZ GLY 18.A O no hydrogen 2.814 N/A LYS 93.A NZ TYR 248.A OH no hydrogen 2.783 N/A ALA 94.A N PRO 91.A O no hydrogen 3.327 N/A LYS 95.A N ASN 87.A OD1 no hydrogen 3.079 N/A GLN 97.A N GLN 97.A OE1 no hydrogen 2.902 N/A TYR 98.A N LYS 95.A O no hydrogen 3.016 N/A TYR 98.A OH TYR 19.A O no hydrogen 2.623 N/A VAL 99.A N PRO 96.A O no hydrogen 3.207 N/A GLY 100.A N ASP 81.A OD1 no hydrogen 3.053 N/A LEU 101.A N TYR 98.A O no hydrogen 3.386 N/A LYS 102.A NZ LYS 78.A O no hydrogen 3.082 N/A THR 105.A N GLU 108.A OE1 no hydrogen 2.965 N/A LEU 106.A N LEU 51.A O no hydrogen 3.037 N/A GLU 108.A N THR 105.A OG1 no hydrogen 2.994 N/A VAL 109.A N THR 105.A O no hydrogen 3.171 N/A LEU 110.A N LEU 106.A O no hydrogen 3.039 N/A ASP 111.A N GLU 107.A O no hydrogen 2.890 N/A ARG 112.A N GLU 108.A O no hydrogen 2.974 N/A ARG 112.A NE GLU 29.A OE2 no hydrogen 2.899 N/A ARG 112.A NH1 ARG 112.A O no hydrogen 2.905 N/A ARG 112.A NH2 GLU 29.A OE2 no hydrogen 3.182 N/A PHE 113.A N VAL 109.A O no hydrogen 3.245 N/A GLY 114.A N LEU 110.A O no hydrogen 2.794 N/A HIS 116.A N PHE 113.A O no hydrogen 2.808 N/A ASN 118.A ND2 ASP 37.A O no hydrogen 2.960 N/A TYR 119.A N GLN 150.A O no hydrogen 2.894 N/A TYR 119.A OH GLY 114.A O no hydrogen 2.625 N/A TYR 120.A N ILE 39.A O no hydrogen 2.851 N/A TYR 120.A OH HIS 223.A ND1 no hydrogen 2.829 N/A ILE 121.A N ILE 152.A O no hydrogen 2.877 N/A GLU 122.A N LEU 41.A O no hydrogen 2.804 N/A THR 123.A N GLN 154.A O no hydrogen 2.947 N/A THR 123.A OG1 SER 160.A OG no hydrogen 2.740 N/A SER 125.A OG ASP 127.A OD1 no hydrogen 2.820 N/A SER 125.A OG THR 128.A OG1 no hydrogen 2.854 N/A THR 128.A N SER 125.A O no hydrogen 2.908 N/A THR 128.A OG1 SER 125.A O no hydrogen 3.258 N/A THR 128.A OG1 SER 125.A OG no hydrogen 2.854 N/A TYR 129.A OH GLN 44.A OE1 no hydrogen 2.566 N/A MET 132.A N TYR 129.A O no hydrogen 3.011 N/A GLU 133.A N GLU 133.A OE1 no hydrogen 3.034 N/A GLU 134.A N GLU 134.A OE1 no hydrogen 2.635 N/A LYS 135.A N GLY 131.A O no hydrogen 2.998 N/A LYS 135.A NZ GLY 49.A O no hydrogen 2.963 N/A LEU 136.A N MET 132.A O no hydrogen 2.866 N/A ILE 137.A N GLU 133.A O no hydrogen 2.916 N/A ALA 138.A N GLU 134.A O no hydrogen 2.975 N/A SER 139.A N LYS 135.A O no hydrogen 2.966 N/A SER 139.A OG LYS 135.A O no hydrogen 3.273 N/A LEU 140.A N LEU 136.A O no hydrogen 2.980 N/A GLN 141.A N ILE 137.A O no hydrogen 2.986 N/A LYS 142.A N ALA 138.A O no hydrogen 3.057 N/A LYS 142.A NZ GLU 107.A OE1 no hydrogen 3.526 N/A HIS 143.A N SER 139.A O no hydrogen 3.175 N/A HIS 143.A NE2 GLU 107.A OE1 no hydrogen 2.776 N/A LYS 144.A N GLN 141.A O no hydrogen 2.931 N/A LYS 144.A NZ GLN 141.A O no hydrogen 2.984 N/A LEU 145.A N LEU 140.A O no hydrogen 2.824 N/A LYS 147.A NZ ASN 118.A OD1 no hydrogen 2.953 N/A GLN 150.A N LYS 147.A O no hydrogen 2.986 N/A GLN 150.A NE2 LYS 115.A O no hydrogen 3.121 N/A GLN 150.A NE2 ALA 117.A O no hydrogen 2.785 N/A ILE 152.A N TYR 119.A O no hydrogen 2.865 N/A ILE 153.A N PRO 172.A O no hydrogen 2.919 N/A GLN 154.A N ILE 121.A O no hydrogen 2.902 N/A GLN 154.A NE2 GLU 40.A OE2 no hydrogen 2.822 N/A GLN 154.A NE2 TYR 120.A O no hydrogen 3.487 N/A SER 155.A N VAL 174.A O no hydrogen 3.342 N/A SER 155.A OG THR 123.A O no hydrogen 2.945 N/A SER 157.A N SER 155.A OG no hydrogen 2.928 N/A GLU 159.A N GLU 159.A OE1 no hydrogen 2.691 N/A SER 160.A N SER 157.A OG no hydrogen 3.160 N/A SER 160.A OG THR 123.A OG1 no hydrogen 2.740 N/A SER 160.A OG LYS 124.A O no hydrogen 3.082 N/A SER 160.A OG GLU 133.A OE2 no hydrogen 2.725 N/A LEU 161.A N SER 157.A O no hydrogen 3.274 N/A VAL 162.A N LYS 158.A O no hydrogen 2.760 N/A LYS 163.A N GLU 159.A O no hydrogen 2.951 N/A LYS 163.A NZ GLU 133.A OE1 no hydrogen 2.692 N/A LYS 163.A NZ GLU 134.A OE1 no hydrogen 2.989 N/A LYS 163.A NZ GLU 134.A OE2 no hydrogen 3.101 N/A VAL 164.A N SER 160.A O no hydrogen 2.897 N/A HIS 165.A N LEU 161.A O no hydrogen 2.803 N/A GLN 166.A N VAL 162.A O no hydrogen 3.004 N/A LEU 167.A N LYS 163.A O no hydrogen 3.154 N/A GLN 168.A N VAL 164.A O no hydrogen 2.856 N/A LEU 171.A N GLN 168.A O no hydrogen 2.906 N/A THR 173.A OG1 TYR 196.A O no hydrogen 2.490 N/A VAL 174.A N ILE 153.A O no hydrogen 2.849 N/A GLN 175.A N GLY 199.A O no hydrogen 3.073 N/A GLN 175.A NE2 PHE 156.A O no hydrogen 3.183 N/A GLN 175.A NE2 LEU 176.A O no hydrogen 3.009 N/A LEU 176.A N SER 155.A O no hydrogen 2.916 N/A LEU 177.A N GLY 201.A O no hydrogen 2.962 N/A GLU 178.A N GLN 181.A OE1 no hydrogen 2.786 N/A MET 182.A N GLU 178.A O no hydrogen 2.957 N/A ALA 183.A N ALA 179.A O no hydrogen 2.787 N/A SER 184.A N LYS 180.A O no hydrogen 3.287 N/A SER 184.A OG LYS 180.A O no hydrogen 2.995 N/A SER 184.A OG GLN 181.A O no hydrogen 3.473 N/A MET 185.A N MET 182.A O no hydrogen 3.190 N/A ALA 189.A N THR 186.A OG1 no hydrogen 3.066 N/A LEU 190.A N THR 186.A O no hydrogen 3.269 N/A GLU 191.A N ASP 187.A O no hydrogen 3.014 N/A ILE 193.A N ALA 189.A O no hydrogen 3.292 N/A LYS 194.A N LEU 190.A O no hydrogen 3.146 N/A LYS 194.A NZ HIS 218.A O no hydrogen 3.088 N/A THR 195.A N GLU 192.A O no hydrogen 2.975 N/A THR 195.A OG1 GLU 192.A O no hydrogen 2.384 N/A TYR 196.A N ILE 193.A O no hydrogen 3.076 N/A TYR 196.A OH GLN 175.A OE1 no hydrogen 2.658 N/A ALA 197.A N ILE 193.A O no hydrogen 2.703 N/A VAL 198.A N THR 173.A O no hydrogen 2.769 N/A ALA 200.A N LEU 221.A O no hydrogen 2.848 N/A GLY 201.A N GLN 175.A O no hydrogen 2.749 N/A ASP 203.A N LEU 177.A O no hydrogen 3.163 N/A TYR 204.A N TYR 225.A O no hydrogen 2.837 N/A LYS 205.A N ASP 203.A OD1 no hydrogen 2.968 N/A LYS 205.A NZ ASP 203.A OD1 no hydrogen 2.844 N/A LYS 205.A NZ ASP 203.A OD2 no hydrogen 3.199 N/A ALA 206.A N ASP 203.A O no hydrogen 3.000 N/A LEU 207.A N TYR 204.A O no hydrogen 3.150 N/A ASN 208.A N ASN 211.A OD1 no hydrogen 2.900 N/A GLN 209.A NE2 GLN 209.A O no hydrogen 2.781 N/A GLN 209.A NE2 TRP 239.A O no hydrogen 2.755 N/A ASN 211.A N ASN 208.A OD1 no hydrogen 2.997 N/A ASN 211.A ND2 ALA 206.A O no hydrogen 2.993 N/A VAL 212.A N ASN 208.A O no hydrogen 3.063 N/A ARG 213.A N GLN 209.A O no hydrogen 3.048 N/A MET 214.A N GLU 210.A O no hydrogen 2.955 N/A ILE 215.A N ASN 211.A O no hydrogen 2.971 N/A ARG 216.A N VAL 212.A O no hydrogen 3.006 N/A ARG 216.A NH1 LEU 220.A O no hydrogen 3.039 N/A SER 217.A N ARG 213.A O no hydrogen 2.881 N/A SER 217.A N MET 214.A O no hydrogen 3.134 N/A SER 217.A OG MET 214.A O no hydrogen 2.351 N/A HIS 218.A N ILE 215.A O no hydrogen 3.153 N/A HIS 218.A NE2 ASP 187.A OD1 no hydrogen 3.125 N/A GLY 219.A N ARG 216.A O no hydrogen 3.078 N/A LEU 221.A N VAL 198.A O no hydrogen 2.892 N/A LEU 222.A N THR 242.A OG1 no hydrogen 2.874 N/A HIS 223.A N ALA 200.A O no hydrogen 3.006 N/A HIS 223.A ND1 TYR 120.A OH no hydrogen 2.829 N/A TYR 225.A N PRO 202.A O no hydrogen 3.060 N/A TYR 225.A OH LEU 177.A O no hydrogen 3.004 N/A VAL 227.A N PHE 245.A O no hydrogen 2.763 N/A ASN 229.A ND2 ASP 232.A OD2 no hydrogen 3.423 N/A MET 233.A N ASN 229.A O no hydrogen 2.978 N/A HIS 234.A N GLU 230.A O no hydrogen 3.112 N/A HIS 234.A ND1 TYR 259.A OH no hydrogen 2.596 N/A ARG 235.A N ALA 231.A O no hydrogen 3.219 N/A ARG 235.A NH1 ASP 232.A OD1 no hydrogen 3.415 N/A ARG 235.A NH2 ASP 232.A OD1 no hydrogen 2.662 N/A LEU 236.A N ASP 232.A O no hydrogen 2.927 N/A LEU 237.A N MET 233.A O no hydrogen 3.100 N/A ASP 238.A N HIS 234.A O no hydrogen 2.981 N/A TRP 239.A N ARG 235.A O no hydrogen 3.045 N/A GLY 240.A N LEU 236.A O no hydrogen 2.979 N/A VAL 241.A N LEU 236.A O no hydrogen 3.122 N/A THR 242.A N LEU 222.A O no hydrogen 2.883 N/A THR 242.A OG1 LEU 222.A O no hydrogen 3.357 N/A VAL 244.A N LEU 9.A O no hydrogen 3.291 N/A PHE 245.A N PRO 224.A O no hydrogen 2.875 N/A THR 246.A N VAL 11.A O no hydrogen 2.895 N/A THR 246.A OG1 VAL 227.A O no hydrogen 2.754 N/A THR 246.A OG1 ASN 228.A OD1 no hydrogen 3.535 N/A ASN 247.A N ASN 228.A OD1 no hydrogen 2.857 N/A TYR 248.A N THR 246.A OG1 no hydrogen 2.987 N/A PHE 252.A N TYR 248.A O no hydrogen 3.191 N/A HIS 253.A N PRO 249.A O no hydrogen 2.922 N/A LYS 254.A N ASP 250.A O no hydrogen 3.137 N/A LYS 254.A NZ GLU 230.A OE1 no hydrogen 3.396 N/A VAL 255.A N LEU 251.A O no hydrogen 3.044 N/A LYS 256.A N PHE 252.A O no hydrogen 2.917 N/A LYS 256.A NZ ILE 8.A O no hydrogen 2.841 N/A LYS 256.A NZ THR 10.A OG1 no hydrogen 3.044 N/A LYS 257.A NZ HIS 253.A NE2 no hydrogen 3.459 N/A GLY 258.A N VAL 255.A O no hydrogen 3.174 N/A TYR 259.A N LYS 256.A O no hydrogen 3.067 N/A TYR 259.A OH HIS 234.A ND1 no hydrogen 2.596 N/A