Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5tco_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A N VAL 15.A O no hydrogen 2.952 N/A TYR 4.A OH TYR 19.A O no hydrogen 2.751 N/A GLN 6.A N TRP 13.A O no hydrogen 3.017 N/A LEU 8.A N THR 11.A O no hydrogen 2.820 N/A THR 11.A N LEU 8.A O no hydrogen 2.847 N/A THR 11.A OG1 LEU 8.A O no hydrogen 3.327 N/A TRP 13.A N GLN 6.A O no hydrogen 2.913 N/A GLU 14.A N TYR 94.A OH no hydrogen 2.988 N/A VAL 15.A N TYR 4.A O no hydrogen 3.046 N/A GLU 17.A N THR 2.A O no hydrogen 2.872 N/A ARG 18.A NE ASP 34.A OD1 no hydrogen 3.098 N/A ARG 18.A NH2 ASP 34.A OD2 no hydrogen 2.867 N/A TYR 19.A N PRO 16.A O no hydrogen 3.056 N/A TYR 19.A OH ASP 79.A OD2 no hydrogen 2.606 N/A GLN 20.A N PHE 33.A O no hydrogen 3.032 N/A GLN 20.A NE2 GLU 17.A O no hydrogen 2.962 N/A SER 23.A N ALA 31.A O no hydrogen 2.838 N/A VAL 25.A N VAL 29.A O no hydrogen 2.906 N/A GLY 26.A N VAL 29.A O no hydrogen 3.475 N/A SER 28.A N LYS 45.A O no hydrogen 3.186 N/A VAL 29.A N GLY 26.A O no hydrogen 3.090 N/A CYS 30.A N VAL 43.A O no hydrogen 2.856 N/A ALA 31.A N SER 23.A O no hydrogen 2.895 N/A ALA 32.A N VAL 41.A O no hydrogen 2.921 N/A PHE 33.A N GLN 20.A O no hydrogen 2.879 N/A ASP 34.A N LEU 39.A O no hydrogen 2.830 N/A THR 35.A N ARG 18.A O no hydrogen 2.783 N/A THR 35.A OG1 ARG 18.A O no hydrogen 2.614 N/A LYS 36.A N ASP 34.A OD1 no hydrogen 3.084 N/A THR 37.A N ASP 34.A O no hydrogen 3.273 N/A THR 37.A OG1 ASP 34.A OD2 no hydrogen 3.071 N/A GLY 38.A N ASP 34.A O no hydrogen 2.775 N/A LEU 39.A N THR 37.A OG1 no hydrogen 3.257 N/A VAL 41.A N ALA 32.A O no hydrogen 2.751 N/A ALA 42.A N THR 97.A O no hydrogen 2.716 N/A VAL 43.A N CYS 30.A O no hydrogen 2.913 N/A LYS 44.A N LEU 95.A O no hydrogen 2.719 N/A LYS 44.A NZ GLU 62.A OE1 no hydrogen 2.733 N/A LYS 44.A NZ GLU 62.A OE2 no hydrogen 3.302 N/A LYS 45.A N SER 28.A O no hydrogen 2.966 N/A LYS 45.A NZ TYR 94.A OH no hydrogen 3.431 N/A LEU 46.A N VAL 93.A O no hydrogen 3.084 N/A GLN 51.A N ARG 48.A O no hydrogen 3.387 N/A HIS 55.A N SER 52.A OG no hydrogen 2.898 N/A HIS 55.A ND1 ARG 48.A O no hydrogen 2.752 N/A ALA 56.A N SER 52.A O no hydrogen 2.900 N/A LYS 57.A N ILE 53.A O no hydrogen 2.908 N/A LYS 57.A NZ GLU 303.A O no hydrogen 2.642 N/A LYS 57.A NZ ARG 305.A O no hydrogen 2.913 N/A ARG 58.A N ILE 54.A O no hydrogen 3.037 N/A THR 59.A N HIS 55.A O no hydrogen 2.895 N/A THR 59.A OG1 PRO 49.A O no hydrogen 3.050 N/A THR 59.A OG1 HIS 55.A O no hydrogen 3.091 N/A TYR 60.A N ALA 56.A O no hydrogen 3.107 N/A ARG 61.A N LYS 57.A O no hydrogen 2.888 N/A ARG 61.A NE GLU 303.A OE1 no hydrogen 2.650 N/A ARG 61.A NE GLU 303.A OE2 no hydrogen 3.468 N/A ARG 61.A NH2 GLU 303.A OE1 no hydrogen 3.523 N/A ARG 61.A NH2 GLU 303.A OE2 no hydrogen 2.756 N/A GLU 62.A N ARG 58.A O no hydrogen 2.989 N/A LEU 63.A N THR 59.A O no hydrogen 3.065 N/A ARG 64.A N TYR 60.A O no hydrogen 2.861 N/A ARG 64.A NH1 TYR 60.A OH no hydrogen 3.144 N/A ARG 64.A NH1 ASP 299.A O no hydrogen 3.434 N/A ARG 64.A NH2 ASP 299.A O no hydrogen 2.753 N/A LEU 65.A N ARG 61.A O no hydrogen 2.747 N/A LEU 66.A N GLU 62.A O no hydrogen 2.981 N/A LYS 67.A N LEU 63.A O no hydrogen 2.955 N/A LYS 67.A NZ GLU 319.A O no hydrogen 2.975 N/A LYS 67.A NZ GLU 319.A OE1 no hydrogen 2.631 N/A HIS 68.A N ARG 64.A O no hydrogen 3.145 N/A HIS 68.A N LEU 65.A O no hydrogen 3.086 N/A HIS 68.A NE2 ASP 296.A O no hydrogen 2.739 N/A MET 69.A N LEU 65.A O no hydrogen 3.180 N/A LYS 70.A N TYR 131.A OH no hydrogen 2.884 N/A ASN 73.A N HIS 71.A ND1 no hydrogen 3.083 N/A ASN 73.A ND2 LEU 155.A O no hydrogen 3.293 N/A VAL 74.A N HIS 71.A O no hydrogen 3.227 N/A ILE 75.A N ILE 157.A O no hydrogen 3.068 N/A LEU 77.A N LEU 66.A O no hydrogen 3.328 N/A LEU 78.A N VAL 96.A O no hydrogen 2.797 N/A ASP 79.A N VAL 96.A O no hydrogen 3.354 N/A PHE 81.A N TYR 94.A O no hydrogen 3.111 N/A THR 82.A OG1 ASP 92.A O no hydrogen 2.834 N/A ALA 84.A N THR 82.A OG1 no hydrogen 3.136 N/A ARG 85.A N GLU 89.A OE2 no hydrogen 2.764 N/A GLU 89.A N SER 86.A OG no hydrogen 3.378 N/A PHE 90.A N LEU 87.A O no hydrogen 3.091 N/A TYR 94.A N PHE 81.A O no hydrogen 3.112 N/A LEU 95.A N LYS 44.A O no hydrogen 2.849 N/A VAL 96.A N ASP 79.A O no hydrogen 2.988 N/A THR 97.A N ALA 42.A O no hydrogen 2.710 N/A THR 97.A OG1 HIS 98.A O no hydrogen 3.164 N/A LEU 99.A N ARG 40.A O no hydrogen 3.082 N/A ASP 103.A N ASN 106.A OD1 no hydrogen 3.035 N/A LEU 104.A N PRO 144.A O no hydrogen 3.200 N/A LEU 104.A N LEU 147.A O no hydrogen 2.896 N/A ASN 106.A N ASP 103.A OD1 no hydrogen 3.278 N/A ILE 107.A N LEU 104.A O no hydrogen 3.089 N/A VAL 108.A N LEU 104.A O no hydrogen 3.091 N/A LYS 109.A N ASN 105.A O no hydrogen 2.811 N/A GLN 111.A N VAL 108.A O no hydrogen 2.792 N/A LYS 112.A NZ THR 196.A O no hydrogen 2.991 N/A LEU 113.A N LEU 194.A O no hydrogen 2.878 N/A HIS 117.A N THR 114.A OG1 no hydrogen 3.074 N/A VAL 118.A N THR 114.A O no hydrogen 2.918 N/A GLN 119.A N ASP 115.A O no hydrogen 2.811 N/A GLN 119.A NE2 ASP 115.A OD2 no hydrogen 3.320 N/A PHE 120.A N ASP 116.A O no hydrogen 3.158 N/A LEU 121.A N HIS 117.A O no hydrogen 3.071 N/A ILE 122.A N VAL 118.A O no hydrogen 2.822 N/A TYR 123.A N GLN 119.A O no hydrogen 2.905 N/A TYR 123.A OH GLU 292.A OE1 no hydrogen 2.454 N/A GLN 124.A N PHE 120.A O no hydrogen 3.067 N/A GLN 124.A NE2 PHE 120.A O no hydrogen 3.290 N/A GLN 124.A NE2 CYS 153.A O no hydrogen 2.963 N/A ILE 125.A N LEU 121.A O no hydrogen 3.143 N/A LEU 126.A N ILE 122.A O no hydrogen 2.845 N/A ARG 127.A N TYR 123.A O no hydrogen 2.864 N/A ARG 127.A NE ASP 291.A O no hydrogen 2.848 N/A ARG 127.A NH1 ASN 73.A OD1 no hydrogen 2.824 N/A ARG 127.A NH2 GLU 72.A OE2 no hydrogen 3.156 N/A ARG 127.A NH2 ASP 291.A O no hydrogen 3.291 N/A ARG 127.A NH2 ASP 291.A OD1 no hydrogen 3.053 N/A GLY 128.A N GLN 124.A O no hydrogen 3.020 N/A LEU 129.A N ILE 125.A O no hydrogen 2.901 N/A LYS 130.A N LEU 126.A O no hydrogen 2.889 N/A LYS 130.A NZ GLU 292.A O no hydrogen 2.945 N/A TYR 131.A N ARG 127.A O no hydrogen 3.481 N/A ILE 132.A N GLY 128.A O no hydrogen 2.983 N/A HIS 133.A N LEU 129.A O no hydrogen 2.711 N/A HIS 133.A NE2 ASP 183.A OD2 no hydrogen 2.728 N/A SER 134.A N LYS 130.A O no hydrogen 2.792 N/A SER 134.A OG TYR 131.A O no hydrogen 2.511 N/A ALA 135.A N ILE 132.A O no hydrogen 2.983 N/A ASP 136.A N HIS 133.A O no hydrogen 2.937 N/A ILE 137.A N ILE 132.A O no hydrogen 3.327 N/A HIS 139.A N ASP 183.A OD2 no hydrogen 2.773 N/A HIS 139.A NE2 LEU 158.A O no hydrogen 2.637 N/A ARG 140.A N ASP 183.A OD1 no hydrogen 2.714 N/A ASP 141.A N HIS 139.A ND1 no hydrogen 3.052 N/A LYS 143.A NZ ASP 141.A OD2 no hydrogen 3.471 N/A ASN 146.A N LYS 143.A O no hydrogen 2.860 N/A ASN 146.A ND2 ASP 141.A O no hydrogen 2.620 N/A LEU 147.A N PRO 144.A O no hydrogen 3.106 N/A ALA 148.A N LYS 156.A O no hydrogen 2.838 N/A VAL 149.A N ALA 102.A O no hydrogen 2.856 N/A ASN 150.A N GLU 154.A O no hydrogen 3.135 N/A ASN 150.A ND2 GLU 154.A OE1 no hydrogen 2.775 N/A CYS 153.A N ASN 150.A O no hydrogen 2.906 N/A CYS 153.A SG HIS 117.A NE2 no hydrogen 3.209 N/A GLU 154.A N ASN 150.A OD1 no hydrogen 2.928 N/A LEU 155.A N GLN 124.A OE1 no hydrogen 2.995 N/A LYS 156.A N ALA 148.A O no hydrogen 2.753 N/A ILE 157.A N ASN 73.A O no hydrogen 3.116 N/A LEU 158.A N ASN 146.A O no hydrogen 2.760 N/A TRP 165.A NE1 GLY 203.A O no hydrogen 3.048 N/A TYR 166.A OH GLU 193.A OE1 no hydrogen 2.394 N/A TYR 166.A OH GLU 193.A OE2 no hydrogen 3.341 N/A ARG 167.A N ARG 164.A O no hydrogen 3.212 N/A ARG 167.A NH2 ASP 141.A OD1 no hydrogen 3.110 N/A GLU 170.A N GLU 170.A OE2 no hydrogen 2.830 N/A ILE 171.A N ALA 168.A O no hydrogen 3.165 N/A LEU 173.A N PRO 169.A O no hydrogen 3.077 N/A ASN 174.A N ILE 171.A O no hydrogen 3.098 N/A TRP 175.A N GLU 170.A O no hydrogen 3.081 N/A MET 176.A N TYR 178.A OH no hydrogen 3.268 N/A TYR 178.A OH GLU 170.A O no hydrogen 3.303 N/A ASN 179.A ND2 SER 268.A OG no hydrogen 2.977 N/A GLN 180.A NE2 HIS 133.A O no hydrogen 2.745 N/A THR 181.A OG1 ASN 179.A OD1 no hydrogen 2.565 N/A THR 181.A OG1 SER 268.A O no hydrogen 2.745 N/A VAL 182.A N ASN 179.A O no hydrogen 3.126 N/A ASP 183.A N GLN 180.A O no hydrogen 3.245 N/A TRP 185.A N THR 181.A O no hydrogen 3.242 N/A SER 186.A N VAL 182.A O no hydrogen 3.439 N/A SER 186.A OG TYR 166.A O no hydrogen 2.573 N/A SER 186.A OG VAL 182.A O no hydrogen 3.376 N/A VAL 187.A N ASP 183.A O no hydrogen 2.940 N/A GLY 188.A N ILE 184.A O no hydrogen 2.922 N/A CYS 189.A N TRP 185.A O no hydrogen 3.088 N/A CYS 189.A SG TRP 165.A O no hydrogen 3.797 N/A CYS 189.A SG TRP 185.A O no hydrogen 3.616 N/A ILE 190.A N SER 186.A O no hydrogen 2.986 N/A MET 191.A N VAL 187.A O no hydrogen 2.822 N/A ALA 192.A N GLY 188.A O no hydrogen 2.910 N/A GLU 193.A N CYS 189.A O no hydrogen 3.235 N/A LEU 194.A N ILE 190.A O no hydrogen 2.903 N/A LEU 195.A N MET 191.A O no hydrogen 3.161 N/A THR 196.A N ALA 192.A O no hydrogen 3.026 N/A THR 196.A OG1 ALA 192.A O no hydrogen 3.047 N/A THR 196.A OG1 ARG 198.A O no hydrogen 3.143 N/A GLY 197.A N GLU 193.A O no hydrogen 2.710 N/A ARG 198.A N THR 196.A OG1 no hydrogen 2.929 N/A GLY 203.A N PHE 201.A O no hydrogen 2.870 N/A GLY 203.A N GLN 209.A OE1 no hydrogen 2.924 N/A THR 204.A N ASP 208.A OD2 no hydrogen 2.704 N/A HIS 206.A NE2 MET 172.A O no hydrogen 2.960 N/A ASP 208.A N ASP 205.A OD1 no hydrogen 2.745 N/A GLN 209.A N ASP 205.A O no hydrogen 2.878 N/A GLN 209.A NE2 TRP 165.A O no hydrogen 3.604 N/A GLN 209.A NE2 PHE 201.A O no hydrogen 3.062 N/A LEU 210.A N HIS 206.A O no hydrogen 3.275 N/A LYS 211.A N ILE 207.A O no hydrogen 2.945 N/A LEU 212.A N ASP 208.A O no hydrogen 2.799 N/A ILE 213.A N GLN 209.A O no hydrogen 3.109 N/A LEU 214.A N LEU 210.A O no hydrogen 2.901 N/A ARG 215.A N LYS 211.A O no hydrogen 3.006 N/A LEU 216.A N LEU 212.A O no hydrogen 3.236 N/A VAL 217.A N ILE 213.A O no hydrogen 2.814 N/A GLY 218.A N LEU 214.A O no hydrogen 2.609 N/A THR 219.A N MET 243.A O no hydrogen 3.230 N/A THR 219.A OG1 MET 243.A O no hydrogen 3.545 N/A LEU 225.A N GLY 221.A O no hydrogen 2.839 N/A LYS 226.A N ALA 222.A O no hydrogen 3.035 N/A LYS 227.A N LEU 224.A O no hydrogen 2.876 N/A LYS 227.A NZ ASP 267.A OD1 no hydrogen 3.150 N/A LYS 227.A NZ ASP 267.A OD2 no hydrogen 2.567 N/A LYS 227.A NZ ASP 269.A OD2 no hydrogen 2.846 N/A ILE 228.A N LEU 225.A O no hydrogen 3.059 N/A SER 232.A OG SER 230.A OG no hydrogen 2.927 N/A ALA 233.A N SER 230.A OG no hydrogen 3.032 N/A ARG 234.A N SER 230.A O no hydrogen 3.079 N/A ARG 234.A NE ILE 228.A O no hydrogen 3.050 N/A ARG 234.A NH2 SER 229.A O no hydrogen 3.340 N/A ASN 235.A N GLU 231.A O no hydrogen 2.657 N/A TYR 236.A N SER 232.A O no hydrogen 2.857 N/A ILE 237.A N ALA 233.A O no hydrogen 3.063 N/A GLN 238.A N ARG 234.A O no hydrogen 2.906 N/A SER 239.A N ASN 235.A O no hydrogen 3.069 N/A SER 239.A N TYR 236.A O no hydrogen 2.973 N/A SER 239.A OG ASN 235.A O no hydrogen 2.833 N/A LEU 240.A N ILE 237.A O no hydrogen 3.209 N/A ALA 249.A N ASN 247.A OD1 no hydrogen 3.116 N/A ASN 250.A N ASN 247.A O no hydrogen 2.888 N/A ASN 253.A ND2 ASP 115.A OD2 no hydrogen 2.882 N/A LEU 255.A N ASN 253.A OD1 no hydrogen 2.886 N/A VAL 257.A N ASN 253.A O no hydrogen 3.129 N/A ASP 258.A N PRO 254.A O no hydrogen 3.006 N/A LEU 259.A N LEU 255.A O no hydrogen 2.978 N/A LEU 260.A N ALA 256.A O no hydrogen 2.853 N/A GLU 261.A N VAL 257.A O no hydrogen 2.962 N/A LYS 262.A N ASP 258.A O no hydrogen 3.288 N/A LYS 262.A N LEU 259.A O no hydrogen 3.090 N/A LYS 262.A NZ ASP 258.A OD2 no hydrogen 2.924 N/A MET 263.A N LEU 259.A O no hydrogen 2.974 N/A LEU 264.A N LEU 260.A O no hydrogen 2.912 N/A ASP 269.A N ASP 267.A OD1 no hydrogen 3.178 N/A LYS 270.A N ASP 267.A O no hydrogen 2.990 N/A ARG 271.A N SER 268.A O no hydrogen 3.414 N/A ARG 271.A NE VAL 265.A O no hydrogen 2.688 N/A ARG 271.A NH1 GLU 170.A OE1 no hydrogen 2.876 N/A ARG 271.A NH1 THR 181.A O no hydrogen 3.171 N/A ARG 271.A NH2 GLU 170.A OE1 no hydrogen 3.459 N/A ARG 271.A NH2 GLU 170.A OE2 no hydrogen 2.968 N/A ARG 271.A NH2 VAL 265.A O no hydrogen 3.336 N/A ARG 271.A NH2 LEU 266.A O no hydrogen 2.825 N/A ILE 272.A N LYS 262.A O no hydrogen 3.084 N/A THR 273.A N GLN 276.A OE1 no hydrogen 2.981 N/A GLN 276.A N THR 273.A OG1 no hydrogen 3.152 N/A ALA 277.A N THR 273.A O no hydrogen 2.880 N/A LEU 278.A N ALA 274.A O no hydrogen 3.009 N/A ALA 279.A N GLN 276.A O no hydrogen 3.157 N/A HIS 280.A N ALA 277.A O no hydrogen 3.120 N/A HIS 280.A NE2 ASP 258.A OD2 no hydrogen 2.859 N/A TYR 282.A N HIS 280.A ND1 no hydrogen 3.180 N/A TYR 282.A OH ASP 115.A OD1 no hydrogen 2.680 N/A PHE 283.A N HIS 280.A O no hydrogen 2.846 N/A ALA 284.A N ALA 281.A O no hydrogen 2.949 N/A GLN 285.A NE2 ASP 116.A OD1 no hydrogen 2.547 N/A GLN 285.A NE2 GLN 119.A OE1 no hydrogen 2.883 N/A TYR 286.A N PHE 283.A O no hydrogen 2.675 N/A HIS 287.A N PHE 283.A O no hydrogen 2.786 N/A HIS 287.A ND1 GLU 292.A OE1 no hydrogen 2.783 N/A ASP 288.A N TYR 123.A OH no hydrogen 3.453 N/A ASP 288.A N GLU 292.A OE1 no hydrogen 3.043 N/A ASP 290.A N ASP 288.A OD1 no hydrogen 2.809 N/A ASP 291.A N ASP 288.A O no hydrogen 2.885 N/A ALA 295.A N SER 134.A OG no hydrogen 2.897 N/A SER 301.A N ASP 299.A OD1 no hydrogen 3.184 N/A SER 301.A OG ASP 299.A OD1 no hydrogen 2.985 N/A GLU 303.A N GLN 300.A O no hydrogen 2.902 N/A SER 304.A N SER 301.A O no hydrogen 3.386 N/A SER 304.A OG SER 301.A O no hydrogen 3.070 N/A ARG 305.A N PHE 302.A O no hydrogen 3.014 N/A ARG 305.A NE SER 301.A O no hydrogen 3.283 N/A ARG 305.A NE SER 304.A OG no hydrogen 3.231 N/A ARG 305.A NH2 SER 304.A OG no hydrogen 2.891 N/A LEU 308.A N GLU 311.A OE1 no hydrogen 2.864 N/A GLU 311.A N LEU 308.A O no hydrogen 2.975 N/A TRP 312.A N LEU 308.A O no hydrogen 3.162 N/A LYS 313.A N ILE 309.A O no hydrogen 2.888 N/A LYS 313.A NZ PHE 90.A O no hydrogen 2.819 N/A SER 314.A N ASP 310.A O no hydrogen 2.967 N/A LEU 315.A N GLU 311.A O no hydrogen 2.909 N/A THR 316.A N TRP 312.A O no hydrogen 3.001 N/A THR 316.A OG1 TRP 312.A O no hydrogen 3.093 N/A TYR 317.A N LYS 313.A O no hydrogen 2.925 N/A ASP 318.A N SER 314.A O no hydrogen 2.922 N/A GLU 319.A N LEU 315.A O no hydrogen 3.121 N/A GLU 319.A N THR 316.A O no hydrogen 2.866 N/A VAL 320.A N THR 316.A O no hydrogen 2.954 N/A ILE 321.A N TYR 317.A O no hydrogen 2.911 N/A SER 322.A N ASP 318.A O no hydrogen 3.130 N/A SER 322.A OG ASP 318.A O no hydrogen 3.063 N/A SER 322.A OG GLU 319.A O no hydrogen 3.463 N/A PHE 323.A N VAL 320.A O no hydrogen 3.041 N/A