Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5tmk_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 1.A N GLY 148.A O no hydrogen 2.936 N/A GLY 1.A N LEU 150.A O no hydrogen 3.065 N/A THR 3.A N VAL 149.A O no hydrogen 3.028 N/A THR 3.A OG1 VAL 149.A O no hydrogen 3.357 N/A SER 5.A N LEU 173.A O no hydrogen 2.981 N/A SER 5.A OG GLY 97.A O no hydrogen 2.359 N/A VAL 7.A N ILE 171.A O no hydrogen 2.826 N/A LEU 9.A N GLY 169.A O no hydrogen 2.780 N/A THR 10.A N TYR 18.A O no hydrogen 2.789 N/A ASN 11.A ND2 ASP 14.A OD1 no hydrogen 2.779 N/A ASN 11.A ND2 ASP 162.A O no hydrogen 3.343 N/A TYR 12.A N GLN 16.A O no hydrogen 2.847 N/A ASP 14.A N ASN 11.A OD1 no hydrogen 2.835 N/A THR 15.A N TYR 12.A O no hydrogen 3.063 N/A THR 15.A OG1 TYR 12.A O no hydrogen 3.300 N/A GLN 16.A N TYR 12.A O no hydrogen 3.077 N/A GLN 16.A NE2 LEU 118.A O no hydrogen 2.887 N/A TYR 17.A OH ASN 160.A O no hydrogen 2.690 N/A TYR 18.A N THR 10.A O no hydrogen 3.165 N/A GLY 19.A N VAL 32.A O no hydrogen 2.918 N/A ILE 21.A N PHE 30.A O no hydrogen 2.950 N/A GLY 22.A N THR 95.A O no hydrogen 2.954 N/A ILE 23.A N GLN 28.A O no hydrogen 2.773 N/A GLY 24.A N ILE 93.A O no hydrogen 2.944 N/A THR 25.A N SER 66.A OG no hydrogen 3.163 N/A THR 25.A OG1 SER 68.A OG no hydrogen 2.890 N/A GLN 28.A N ILE 23.A O no hydrogen 2.845 N/A GLN 28.A NE2 ASP 62.A O no hydrogen 2.775 N/A PHE 30.A N ILE 21.A O no hydrogen 2.867 N/A LYS 31.A N ASP 122.A OD2 no hydrogen 2.801 N/A VAL 32.A N GLY 19.A O no hydrogen 2.775 N/A VAL 33.A N GLY 123.A O no hydrogen 3.039 N/A ASP 35.A N VAL 125.A O no hydrogen 2.750 N/A THR 36.A N THR 220.A OG1 no hydrogen 2.857 N/A THR 36.A OG1 VAL 218.A O no hydrogen 2.656 N/A THR 36.A OG1 THR 220.A OG1 no hydrogen 3.221 N/A GLY 37.A N ASP 35.A OD1 no hydrogen 2.779 N/A SER 38.A N ASP 35.A O no hydrogen 3.411 N/A SER 38.A OG ASP 35.A OD2 no hydrogen 2.536 N/A SER 39.A OG PHE 129.A O no hydrogen 2.733 N/A ASN 40.A ND2 ILE 134.A O no hydrogen 2.966 N/A TRP 42.A N VAL 124.A O no hydrogen 3.029 N/A TRP 42.A NE1 TYR 80.A OH no hydrogen 2.795 N/A VAL 43.A N GLY 106.A O no hydrogen 3.069 N/A SER 45.A N VAL 108.A O no hydrogen 2.730 N/A SER 45.A OG GLU 107.A OE1 no hydrogen 2.686 N/A SER 46.A N PHE 61.A O no hydrogen 2.838 N/A SER 46.A OG PHE 61.A O no hydrogen 3.157 N/A LYS 47.A N SER 45.A OG no hydrogen 3.026 N/A CYS 48.A N SER 45.A O no hydrogen 3.124 N/A CYS 48.A SG SER 49.A O no hydrogen 3.445 N/A CYS 48.A SG THR 109.A O no hydrogen 3.324 N/A ARG 50.A NE CYS 48.A O no hydrogen 3.104 N/A ARG 50.A NH2 SER 46.A O no hydrogen 2.656 N/A LEU 51.A N SER 49.A OG no hydrogen 3.234 N/A TYR 52.A N SER 49.A O no hydrogen 3.165 N/A CYS 55.A N TYR 52.A O no hydrogen 3.055 N/A VAL 56.A N THR 53.A O no hydrogen 2.940 N/A TYR 57.A N THR 53.A O no hydrogen 3.245 N/A TYR 57.A N ALA 54.A O no hydrogen 3.377 N/A HIS 58.A N ALA 54.A O no hydrogen 3.183 N/A HIS 58.A ND1 ALA 54.A O no hydrogen 2.782 N/A HIS 58.A NE2 ALA 119.A O no hydrogen 2.872 N/A LYS 59.A N ASP 122.A OD1 no hydrogen 3.032 N/A PHE 61.A N PRO 44.A O no hydrogen 2.682 N/A ASP 62.A N GLN 28.A OE1 no hydrogen 2.900 N/A SER 64.A N ASP 62.A OD1 no hydrogen 3.103 N/A ASP 65.A N ASP 62.A O no hydrogen 3.117 N/A SER 66.A N ALA 63.A O no hydrogen 3.164 N/A SER 66.A OG ASP 92.A OD1 no hydrogen 3.441 N/A SER 66.A OG ASP 92.A OD2 no hydrogen 2.633 N/A SER 67.A N THR 25.A O no hydrogen 2.913 N/A SER 67.A OG THR 25.A O no hydrogen 3.300 N/A SER 68.A OG THR 25.A OG1 no hydrogen 2.890 N/A SER 68.A OG SER 66.A OG no hydrogen 3.259 N/A SER 68.A OG ASP 92.A OD1 no hydrogen 2.654 N/A LYS 70.A N GLN 91.A O no hydrogen 2.785 N/A GLY 73.A N LEU 89.A O no hydrogen 2.831 N/A THR 74.A N ASN 72.A OD1 no hydrogen 3.399 N/A THR 74.A OG1 ASN 72.A OD1 no hydrogen 2.644 N/A LEU 76.A N GLY 87.A O no hydrogen 2.819 N/A THR 77.A OG1 SER 86.A OG no hydrogen 3.006 N/A LEU 78.A N VAL 85.A O no hydrogen 2.870 N/A TYR 80.A N GLY 83.A O no hydrogen 3.031 N/A GLY 83.A N TYR 80.A O no hydrogen 3.469 N/A VAL 85.A N LEU 78.A O no hydrogen 3.035 N/A SER 86.A N GLU 110.A O no hydrogen 3.171 N/A SER 86.A OG LEU 76.A O no hydrogen 3.368 N/A SER 86.A OG THR 77.A OG1 no hydrogen 3.006 N/A GLY 87.A N LEU 76.A O no hydrogen 2.840 N/A PHE 88.A N GLU 107.A O no hydrogen 3.022 N/A LEU 89.A N THR 74.A O no hydrogen 2.752 N/A SER 90.A N PHE 105.A O no hydrogen 2.860 N/A SER 90.A OG GLU 107.A OE2 no hydrogen 2.631 N/A GLN 91.A N LYS 70.A O no hydrogen 2.939 N/A ASP 92.A N GLN 103.A O no hydrogen 3.156 N/A ILE 93.A N ASP 92.A OD1 no hydrogen 2.697 N/A ILE 94.A N VAL 101.A O no hydrogen 2.742 N/A THR 95.A N GLY 22.A O no hydrogen 2.769 N/A VAL 96.A N ILE 99.A O no hydrogen 2.864 N/A ILE 99.A N VAL 96.A O no hydrogen 3.247 N/A VAL 101.A N ILE 94.A O no hydrogen 2.901 N/A GLN 103.A N ASP 92.A O no hydrogen 2.887 N/A GLN 103.A NE2 MET 104.A O no hydrogen 2.920 N/A GLN 103.A NE2 THR 138.A O no hydrogen 2.808 N/A PHE 105.A N SER 90.A O no hydrogen 2.770 N/A GLY 106.A N VAL 41.A O no hydrogen 2.642 N/A GLU 107.A N PHE 88.A O no hydrogen 2.771 N/A VAL 108.A N VAL 43.A O no hydrogen 2.887 N/A THR 109.A N SER 86.A O no hydrogen 2.820 N/A THR 109.A OG1 SER 86.A O no hydrogen 3.538 N/A THR 109.A OG1 GLU 110.A OE2 no hydrogen 3.414 N/A GLU 110.A N SER 86.A O no hydrogen 3.060 N/A MET 117.A N ALA 113.A O no hydrogen 2.691 N/A LEU 118.A N PRO 115.A O no hydrogen 2.972 N/A ALA 119.A N PHE 116.A O no hydrogen 3.193 N/A GLU 120.A N GLN 16.A OE1 no hydrogen 2.648 N/A ASP 122.A N LYS 31.A O no hydrogen 2.663 N/A GLY 123.A N LYS 31.A O no hydrogen 3.080 N/A VAL 124.A N TRP 42.A O no hydrogen 3.017 N/A VAL 125.A N VAL 33.A O no hydrogen 2.650 N/A GLY 126.A N ASN 40.A O no hydrogen 2.885 N/A MET 127.A N ASP 35.A O no hydrogen 2.639 N/A GLY 128.A N SER 38.A O no hydrogen 2.789 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.927 N/A GLN 132.A N PHE 129.A O no hydrogen 3.240 N/A ALA 133.A N ILE 130.A O no hydrogen 3.098 N/A ILE 134.A N ASN 40.A OD1 no hydrogen 2.848 N/A ARG 136.A N ALA 133.A O no hydrogen 3.278 N/A ASN 143.A N PRO 139.A O no hydrogen 3.127 N/A ASN 143.A ND2 GLN 103.A OE1 no hydrogen 2.741 N/A ILE 144.A N ILE 140.A O no hydrogen 2.874 N/A ILE 145.A N PHE 141.A O no hydrogen 2.862 N/A SER 146.A N ASP 142.A O no hydrogen 3.161 N/A SER 146.A OG ASP 142.A O no hydrogen 3.123 N/A GLN 147.A N ILE 144.A O no hydrogen 3.277 N/A GLN 147.A NE2 THR 100.A O no hydrogen 3.482 N/A GLY 148.A N ILE 145.A O no hydrogen 2.902 N/A LYS 151.A N THR 3.A O no hydrogen 2.907 N/A PHE 155.A N PHE 320.A O no hydrogen 2.959 N/A SER 156.A N VAL 172.A O no hydrogen 2.850 N/A SER 156.A OG GLY 175.A O no hydrogen 2.870 N/A PHE 157.A N THR 318.A O no hydrogen 2.782 N/A TYR 158.A N GLN 170.A O no hydrogen 2.791 N/A TYR 159.A OH THR 220.A O no hydrogen 2.634 N/A ASN 160.A N GLY 168.A O no hydrogen 3.048 N/A ASN 160.A ND2 LEU 167.A O no hydrogen 2.690 N/A ASP 162.A N ASN 160.A OD1 no hydrogen 3.391 N/A SER 164.A OG SER 163.A O no hydrogen 3.058 N/A GLN 170.A N TYR 158.A O no hydrogen 2.897 N/A GLN 170.A NE2 ASP 177.A OD2 no hydrogen 2.929 N/A ILE 171.A N VAL 7.A O no hydrogen 2.991 N/A VAL 172.A N SER 156.A O no hydrogen 2.989 N/A LEU 173.A N SER 5.A O no hydrogen 2.621 N/A GLY 174.A N VAL 154.A O no hydrogen 2.805 N/A SER 176.A OG TYR 181.A OH no hydrogen 3.056 N/A ASP 177.A N TYR 317.A OH no hydrogen 2.793 N/A GLN 179.A N ASP 177.A OD1 no hydrogen 3.206 N/A HIS 180.A N ASP 177.A O no hydrogen 2.945 N/A TYR 181.A OH SER 176.A OG no hydrogen 3.056 N/A GLU 182.A N LEU 331.A O no hydrogen 3.078 N/A HIS 186.A N PHE 329.A O no hydrogen 2.751 N/A HIS 186.A ND1 TYR 270.A OH no hydrogen 2.727 N/A HIS 186.A NE2 GLY 266.A O no hydrogen 3.046 N/A TYR 187.A OH GLU 319.A OE1 no hydrogen 2.777 N/A ILE 188.A N ILE 327.A O no hydrogen 2.799 N/A LEU 190.A N ASN 325.A O no hydrogen 3.086 N/A ILE 191.A N GLN 197.A O no hydrogen 3.181 N/A TRP 196.A NE1 MET 127.A O no hydrogen 3.086 N/A GLN 197.A N VAL 195.A O no hydrogen 2.874 N/A GLN 197.A NE2 THR 302.A O no hydrogen 3.017 N/A GLN 197.A NE2 THR 305.A OG1 no hydrogen 2.947 N/A ILE 198.A N ALA 216.A O no hydrogen 2.933 N/A MET 200.A N CYS 214.A O no hydrogen 2.895 N/A LYS 201.A N HIS 264.A O no hydrogen 2.805 N/A VAL 203.A N LEU 209.A O no hydrogen 2.976 N/A SER 204.A N SER 262.A O no hydrogen 2.790 N/A SER 204.A OG THR 207.A OG1 no hydrogen 3.081 N/A GLY 206.A N ASP 260.A O no hydrogen 3.061 N/A THR 207.A OG1 SER 204.A OG no hydrogen 3.081 N/A LEU 208.A N VAL 203.A O no hydrogen 3.333 N/A LEU 209.A N VAL 203.A O no hydrogen 3.414 N/A CYS 210.A SG MET 200.A O no hydrogen 3.366 N/A GLY 213.A N CYS 210.A O no hydrogen 3.056 N/A CYS 214.A N MET 200.A O no hydrogen 2.940 N/A ALA 216.A N ILE 198.A O no hydrogen 2.986 N/A LEU 217.A N TRP 306.A O no hydrogen 2.665 N/A VAL 218.A N TRP 196.A O no hydrogen 2.899 N/A ASP 219.A N LEU 308.A O no hydrogen 2.977 N/A THR 220.A N THR 36.A OG1 no hydrogen 2.885 N/A THR 220.A OG1 PHE 34.A O no hydrogen 2.630 N/A THR 220.A OG1 THR 36.A OG1 no hydrogen 3.221 N/A GLY 221.A N ASP 219.A OD1 no hydrogen 3.113 N/A ALA 222.A N ASP 219.A O no hydrogen 3.160 N/A SER 223.A OG THR 15.A O no hydrogen 2.635 N/A ILE 225.A N ALA 292.A O no hydrogen 3.039 N/A SER 226.A N ALA 307.A O no hydrogen 2.966 N/A GLY 227.A N HIS 294.A O no hydrogen 3.329 N/A SER 228.A OG SER 231.A OG no hydrogen 2.577 N/A THR 229.A N ASP 297.A OD1 no hydrogen 3.004 N/A THR 229.A OG1 ASP 297.A OD1 no hydrogen 3.027 N/A THR 229.A OG1 ASP 297.A OD2 no hydrogen 2.689 N/A SER 231.A N SER 228.A OG no hydrogen 3.391 N/A SER 231.A OG SER 228.A OG no hydrogen 2.577 N/A ILE 232.A N SER 228.A O no hydrogen 2.836 N/A GLU 233.A N THR 229.A O no hydrogen 2.858 N/A LYS 234.A N SER 230.A O no hydrogen 3.366 N/A LEU 235.A N SER 231.A O no hydrogen 3.165 N/A MET 236.A N ILE 232.A O no hydrogen 2.812 N/A GLU 237.A N GLU 233.A O no hydrogen 2.981 N/A ALA 238.A N LYS 234.A O no hydrogen 3.164 N/A LEU 239.A N LEU 235.A O no hydrogen 3.060 N/A LEU 239.A N MET 236.A O no hydrogen 3.210 N/A ALA 241.A N MET 236.A O no hydrogen 2.963 N/A LYS 242.A N VAL 249.A O no hydrogen 2.967 N/A ARG 244.A N ASP 247.A O no hydrogen 2.954 N/A ARG 244.A NE ASP 247.A OD1 no hydrogen 2.960 N/A ARG 244.A NH1 ASP 247.A OD1 no hydrogen 3.284 N/A ARG 244.A NH1 ASP 247.A OD2 no hydrogen 2.864 N/A VAL 249.A N LYS 242.A O no hydrogen 3.097 N/A VAL 250.A N CYS 289.A O no hydrogen 2.969 N/A CYS 252.A N LYS 287.A O no hydrogen 2.969 N/A CYS 252.A SG LYS 287.A O no hydrogen 3.451 N/A GLU 254.A N LYS 251.A O no hydrogen 2.747 N/A THR 257.A N GLU 254.A O no hydrogen 3.083 N/A THR 257.A OG1 GLU 254.A O no hydrogen 2.678 N/A LEU 258.A N GLY 255.A O no hydrogen 3.142 N/A ILE 261.A N LEU 272.A O no hydrogen 2.815 N/A SER 262.A N SER 204.A O no hydrogen 2.812 N/A SER 262.A OG THR 271.A OG1 no hydrogen 3.167 N/A PHE 263.A N TYR 270.A O no hydrogen 2.770 N/A HIS 264.A N GLY 202.A O no hydrogen 2.837 N/A HIS 264.A ND1 GLU 269.A OE1 no hydrogen 3.015 N/A LEU 265.A N LYS 268.A O no hydrogen 2.899 N/A LYS 268.A N LEU 265.A O no hydrogen 3.130 N/A TYR 270.A N PHE 263.A O no hydrogen 2.862 N/A TYR 270.A OH HIS 186.A ND1 no hydrogen 2.727 N/A THR 271.A OG1 SER 262.A OG no hydrogen 3.167 N/A THR 271.A OG1 GLU 269.A O no hydrogen 3.530 N/A LEU 272.A N ILE 261.A O no hydrogen 2.748 N/A THR 273.A N ASP 276.A OD2 no hydrogen 2.910 N/A THR 273.A OG1 ASP 276.A OD2 no hydrogen 2.783 N/A SER 274.A OG GLY 255.A O no hydrogen 3.439 N/A SER 274.A OG PRO 256.A O no hydrogen 3.201 N/A SER 274.A OG LEU 258.A O no hydrogen 3.559 N/A ASP 276.A N THR 273.A O no hydrogen 2.851 N/A TYR 277.A N SER 274.A O no hydrogen 3.106 N/A TYR 277.A OH PRO 259.A O no hydrogen 2.624 N/A VAL 278.A N SER 274.A O no hydrogen 2.768 N/A PHE 279.A N THR 290.A O no hydrogen 3.040 N/A GLN 280.A NE2 CYS 252.A O no hydrogen 3.284 N/A GLU 281.A N PHE 279.A O no hydrogen 2.805 N/A SER 284.A N SER 282.A OG no hydrogen 3.046 N/A LYS 286.A N SER 284.A OG no hydrogen 3.031 N/A CYS 289.A N VAL 250.A O no hydrogen 2.727 N/A CYS 289.A SG PHE 279.A O no hydrogen 3.340 N/A CYS 289.A SG SER 282.A O no hydrogen 4.007 N/A THR 290.A OG1 ASP 247.A OD2 no hydrogen 2.922 N/A LEU 291.A N TYR 248.A O no hydrogen 2.919 N/A ALA 292.A N TYR 277.A O no hydrogen 2.663 N/A HIS 294.A N ILE 225.A O no hydrogen 2.994 N/A MET 296.A N GLY 227.A O no hydrogen 2.746 N/A GLY 303.A N PRO 299.A O no hydrogen 2.939 N/A THR 305.A OG1 LEU 215.A O no hydrogen 2.986 N/A THR 305.A OG1 TRP 306.A O no hydrogen 2.873 N/A TRP 306.A N LEU 215.A O no hydrogen 2.870 N/A ALA 307.A N SER 226.A O no hydrogen 2.720 N/A LEU 308.A N LEU 217.A O no hydrogen 2.667 N/A ALA 310.A N ALA 222.A O no hydrogen 2.814 N/A THR 311.A N SER 223.A O no hydrogen 3.191 N/A THR 311.A OG1 SER 223.A O no hydrogen 3.248 N/A THR 311.A OG1 ALA 292.A O no hydrogen 3.042 N/A PHE 312.A N GLY 309.A O no hydrogen 2.930 N/A ILE 313.A N GLY 309.A O no hydrogen 3.059 N/A ARG 314.A N ALA 310.A O no hydrogen 2.827 N/A ARG 314.A NH1 ASP 14.A O no hydrogen 2.717 N/A ARG 314.A NH1 TYR 17.A OH no hydrogen 3.204 N/A LYS 315.A NZ THR 271.A O no hydrogen 2.754 N/A LYS 315.A NZ ASP 276.A OD2 no hydrogen 3.005 N/A PHE 316.A N PHE 312.A O no hydrogen 3.050 N/A THR 318.A N PHE 157.A O no hydrogen 3.165 N/A THR 318.A OG1 PHE 316.A O no hydrogen 2.880 N/A GLU 319.A N GLY 328.A O no hydrogen 2.801 N/A PHE 320.A N PHE 155.A O no hydrogen 2.655 N/A ASP 321.A N ARG 326.A O no hydrogen 2.984 N/A ARG 323.A NH1 ASN 324.A OD1 no hydrogen 3.481 N/A ASN 324.A N ASP 321.A OD1 no hydrogen 3.209 N/A ASN 324.A ND2 ASP 321.A OD1 no hydrogen 3.400 N/A ASN 324.A ND2 ASP 321.A OD2 no hydrogen 2.784 N/A ARG 326.A N ASP 321.A O no hydrogen 3.227 N/A ARG 326.A NE ASP 321.A OD2 no hydrogen 2.855 N/A ARG 326.A NH1 ASP 321.A OD2 no hydrogen 3.371 N/A ILE 327.A N ILE 188.A O no hydrogen 2.796 N/A GLY 328.A N GLU 319.A O no hydrogen 2.789 N/A PHE 329.A N HIS 186.A O no hydrogen 2.819 N/A ALA 330.A N TYR 317.A O no hydrogen 2.971 N/A ALA 332.A N LYS 315.A O no hydrogen 2.894 N/A ARG 333.A N HIS 180.A O no hydrogen 3.050 N/A ARG 333.A NE TYR 181.A O no hydrogen 3.109 N/A