Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5tpa_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 1.A ND2 LYS 66.A O no hydrogen 2.776 N/A HIS 2.A ND1 THR 68.A OG1 no hydrogen 3.222 N/A LEU 3.A N THR 68.A O no hydrogen 2.829 N/A SER 4.A OG ARG 98.A O no hydrogen 2.927 N/A ILE 5.A N ASP 70.A O no hydrogen 3.049 N/A VAL 6.A N MET 101.A O no hydrogen 3.030 N/A THR 7.A N TYR 72.A O no hydrogen 2.825 N/A THR 7.A OG1 VAL 103.A O no hydrogen 2.711 N/A LEU 8.A N THR 7.A OG1 no hydrogen 2.879 N/A GLU 10.A N VAL 14.A O no hydrogen 2.920 N/A VAL 14.A N GLU 10.A O no hydrogen 2.833 N/A ILE 15.A N LYS 51.A O no hydrogen 2.771 N/A VAL 16.A N GLU 9.A OE2 no hydrogen 3.212 N/A GLU 17.A N CYS 49.A O no hydrogen 2.780 N/A ASP 20.A N THR 22.A O no hydrogen 3.214 N/A CYS 23.A SG LYS 48.A O no hydrogen 3.397 N/A THR 27.A N VAL 24.A O no hydrogen 3.090 N/A THR 27.A OG1 VAL 24.A O no hydrogen 2.775 N/A VAL 28.A N CYS 50.A O no hydrogen 2.768 N/A CYS 30.A N LYS 48.A O no hydrogen 2.940 N/A ARG 31.A N LEU 71.A O no hydrogen 3.023 N/A ARG 31.A NE ASP 70.A OD1 no hydrogen 3.029 N/A ARG 31.A NE ASP 70.A OD2 no hydrogen 3.361 N/A ARG 31.A NH2 ASP 70.A OD2 no hydrogen 3.151 N/A LYS 32.A N VAL 46.A O no hydrogen 2.988 N/A VAL 34.A N MET 44.A O no hydrogen 2.725 N/A LYS 35.A NZ ASN 37.A O no hydrogen 3.510 N/A LYS 35.A NZ ASN 38.A OD1 no hydrogen 3.295 N/A ILE 36.A N GLU 42.A O no hydrogen 2.996 N/A SER 39.A N ASN 37.A OD1 no hydrogen 2.750 N/A GLU 42.A N THR 40.A OG1 no hydrogen 3.005 N/A MET 44.A N VAL 34.A O no hydrogen 2.798 N/A VAL 46.A N LYS 32.A O no hydrogen 2.737 N/A LYS 48.A N CYS 30.A O no hydrogen 2.766 N/A LYS 48.A NZ ASP 18.A OD1 no hydrogen 2.889 N/A CYS 49.A N GLU 17.A O no hydrogen 2.805 N/A CYS 50.A N VAL 28.A O no hydrogen 2.746 N/A LYS 51.A N ILE 15.A O no hydrogen 2.991 N/A PHE 53.A N PRO 12.A O no hydrogen 3.006 N/A CYS 54.A N PHE 13.A O no hydrogen 3.078 N/A CYS 54.A SG GLY 104.A O no hydrogen 3.359 N/A ASP 56.A N GLY 52.A O no hydrogen 2.963 N/A ILE 57.A N PHE 53.A O no hydrogen 3.101 N/A LEU 58.A N CYS 54.A O no hydrogen 3.009 N/A LYS 59.A N ILE 55.A O no hydrogen 2.979 N/A LYS 59.A NZ ASN 26.A O no hydrogen 3.310 N/A LYS 59.A NZ ASP 56.A OD1 no hydrogen 3.320 N/A LYS 60.A N ASP 56.A O no hydrogen 3.030 N/A LYS 60.A NZ GLU 262.A OE1 no hydrogen 2.795 N/A LEU 61.A N ILE 57.A O no hydrogen 2.919 N/A SER 62.A N LEU 58.A O no hydrogen 2.802 N/A SER 62.A OG PHE 67.A O no hydrogen 2.708 N/A ARG 63.A N LYS 59.A O no hydrogen 3.292 N/A THR 64.A N LYS 60.A O no hydrogen 2.887 N/A THR 64.A OG1 LYS 60.A O no hydrogen 2.938 N/A VAL 65.A N LEU 61.A O no hydrogen 2.799 N/A PHE 67.A N SER 62.A O no hydrogen 2.943 N/A THR 68.A N ASN 1.A O no hydrogen 2.980 N/A THR 68.A OG1 HIS 2.A ND1 no hydrogen 3.222 N/A ASP 70.A N LEU 3.A O no hydrogen 2.903 N/A TYR 72.A N ILE 5.A O no hydrogen 2.822 N/A TYR 72.A OH GLU 93.A OE1 no hydrogen 2.743 N/A LEU 73.A N ARG 31.A O no hydrogen 2.860 N/A VAL 74.A N THR 7.A O no hydrogen 3.078 N/A LYS 78.A NZ LYS 186.A O no hydrogen 3.450 N/A HIS 79.A NE2 GLU 10.A OE1 no hydrogen 3.121 N/A LYS 81.A N ASN 88.A OD1 no hydrogen 2.985 N/A LYS 81.A NZ ASN 162.A OD1 no hydrogen 3.074 N/A LYS 82.A NZ GLU 111.A OE1 no hydrogen 3.382 N/A VAL 83.A N VAL 86.A O no hydrogen 2.896 N/A VAL 86.A N VAL 83.A O no hydrogen 2.839 N/A ASN 88.A N LYS 81.A O no hydrogen 2.997 N/A GLY 89.A N ASN 76.A O no hydrogen 2.797 N/A MET 90.A N LYS 78.A O no hydrogen 2.856 N/A ILE 91.A N HIS 79.A O no hydrogen 3.200 N/A GLY 92.A N ASN 88.A O no hydrogen 2.953 N/A GLU 93.A N GLY 89.A O no hydrogen 3.198 N/A VAL 94.A N MET 90.A O no hydrogen 3.389 N/A VAL 95.A N ILE 91.A O no hydrogen 2.849 N/A TYR 96.A N GLY 92.A O no hydrogen 2.879 N/A GLN 97.A N VAL 94.A O no hydrogen 3.034 N/A ARG 98.A N GLU 93.A O no hydrogen 2.802 N/A ARG 98.A NE GLU 93.A OE1 no hydrogen 3.359 N/A ARG 98.A NE GLU 93.A OE2 no hydrogen 3.377 N/A ARG 98.A NH2 GLU 93.A OE2 no hydrogen 3.521 N/A ALA 99.A N GLU 93.A O no hydrogen 3.222 N/A VAL 100.A N SER 4.A O no hydrogen 2.794 N/A ALA 102.A N ALA 239.A O no hydrogen 2.882 N/A VAL 103.A N VAL 6.A O no hydrogen 2.981 N/A SER 105.A OG GLU 10.A OE1 no hydrogen 2.710 N/A SER 105.A OG HIS 79.A NE2 no hydrogen 3.334 N/A ILE 108.A N GLY 235.A O no hydrogen 2.904 N/A ARG 112.A N ASN 109.A OD1 no hydrogen 2.800 N/A ARG 112.A NH1 THR 107.A O no hydrogen 2.870 N/A ARG 112.A NH2 GLY 80.A O no hydrogen 2.944 N/A SER 113.A N ASN 109.A O no hydrogen 3.139 N/A SER 113.A OG ASN 109.A O no hydrogen 2.746 N/A VAL 115.A N ARG 112.A O no hydrogen 3.249 N/A VAL 116.A N ARG 112.A O no hydrogen 3.100 N/A ASP 117.A N LEU 240.A O no hydrogen 2.771 N/A SER 119.A N ILE 238.A O no hydrogen 2.960 N/A SER 119.A OG VAL 120.A O no hydrogen 2.861 N/A VAL 120.A N ASP 251.A OD1 no hydrogen 2.860 N/A PHE 122.A N TYR 236.A O no hydrogen 2.842 N/A THR 125.A N THR 234.A O no hydrogen 2.997 N/A THR 125.A OG1 ASP 206.A OD1 no hydrogen 2.641 N/A ILE 127.A N PHE 231.A O no hydrogen 2.849 N/A SER 128.A N TYR 205.A O no hydrogen 2.900 N/A SER 128.A OG TYR 229.A O no hydrogen 2.902 N/A MET 130.A N PHE 203.A O no hydrogen 2.875 N/A VAL 131.A N VAL 223.A O no hydrogen 2.821 N/A ARG 133.A N LYS 221.A O no hydrogen 2.814 N/A ARG 133.A NE CYS 220.A O no hydrogen 3.185 N/A ARG 133.A NH2 CYS 220.A O no hydrogen 2.782 N/A THR 135.A N SER 132.A O no hydrogen 3.163 N/A THR 135.A OG1 SER 132.A O no hydrogen 2.716 N/A THR 138.A N ASP 142.A OD2 no hydrogen 2.769 N/A THR 138.A OG1 ASP 142.A OD2 no hydrogen 3.099 N/A ASP 142.A N GLY 139.A O no hydrogen 2.762 N/A LYS 144.A N ASP 142.A OD1 no hydrogen 2.990 N/A LYS 144.A NZ GLN 136.A O no hydrogen 3.252 N/A PHE 145.A N ASP 142.A O no hydrogen 2.887 N/A GLN 146.A N ASP 142.A O no hydrogen 3.049 N/A ARG 147.A N LYS 143.A O no hydrogen 3.168 N/A ARG 147.A NE ASP 150.A OD1 no hydrogen 3.548 N/A ARG 147.A NE ASP 150.A OD2 no hydrogen 2.756 N/A ARG 147.A NH2 ASP 150.A OD1 no hydrogen 3.520 N/A HIS 149.A ND1 TYR 175.A OH no hydrogen 2.865 N/A ASP 150.A N ARG 147.A O no hydrogen 3.143 N/A ARG 156.A N ASP 201.A OD2 no hydrogen 2.738 N/A ARG 156.A NE ASP 201.A OD2 no hydrogen 3.512 N/A ARG 156.A NH1 GLY 198.A O no hydrogen 2.752 N/A ARG 156.A NH2 GLY 198.A O no hydrogen 2.792 N/A ARG 156.A NH2 ASP 201.A OD1 no hydrogen 2.747 N/A GLY 158.A N ALA 202.A O no hydrogen 3.323 N/A THR 159.A OG1 ILE 204.A O no hydrogen 2.627 N/A ASN 162.A N GLU 166.A OE1 no hydrogen 2.768 N/A ARG 167.A N GLY 163.A O no hydrogen 3.323 N/A ARG 167.A NH1 ASN 171.A OD1 no hydrogen 3.072 N/A ASN 168.A N SER 164.A O no hydrogen 3.089 N/A ILE 169.A N THR 165.A O no hydrogen 2.965 N/A ARG 170.A N GLU 166.A O no hydrogen 2.726 N/A ASN 171.A N ARG 167.A O no hydrogen 3.117 N/A ASN 172.A N ASN 168.A O no hydrogen 2.921 N/A ASN 172.A ND2 ASN 168.A OD1 no hydrogen 3.192 N/A TYR 173.A N ILE 169.A O no hydrogen 2.773 N/A TYR 175.A OH HIS 149.A ND1 no hydrogen 2.865 N/A HIS 177.A N TYR 173.A O no hydrogen 2.960 N/A GLN 178.A N PRO 174.A O no hydrogen 3.252 N/A GLN 178.A NE2 TYR 175.A O no hydrogen 3.079 N/A TYR 179.A N TYR 175.A O no hydrogen 3.060 N/A TYR 179.A OH PHE 155.A O no hydrogen 2.641 N/A MET 180.A N MET 176.A O no hydrogen 2.993 N/A THR 181.A OG1 GLN 178.A O no hydrogen 3.383 N/A LYS 182.A NZ TYR 179.A O no hydrogen 3.475 N/A PHE 183.A N MET 180.A O no hydrogen 2.828 N/A ASN 184.A N THR 181.A O no hydrogen 3.243 N/A GLN 185.A N THR 159.A O no hydrogen 3.018 N/A GLN 185.A NE2 PHE 183.A O no hydrogen 2.860 N/A ALA 191.A N GLY 187.A O no hydrogen 3.085 N/A LEU 192.A N VAL 188.A O no hydrogen 2.930 N/A VAL 193.A N GLU 189.A O no hydrogen 3.182 N/A SER 194.A N ASP 190.A O no hydrogen 3.020 N/A SER 194.A OG.A GLN 185.A OE1 no hydrogen 2.858 N/A SER 194.A OG.A ASP 190.A O no hydrogen 2.680 N/A LEU 195.A N ALA 191.A O no hydrogen 3.182 N/A LYS 196.A N LEU 192.A O no hydrogen 2.957 N/A LYS 196.A NZ ASP 217.A OD1 no hydrogen 2.753 N/A LYS 196.A NZ ASP 217.A OD2 no hydrogen 3.411 N/A THR 197.A N VAL 193.A O no hydrogen 2.837 N/A THR 197.A OG1 VAL 193.A O no hydrogen 3.030 N/A GLY 198.A N LEU 195.A O no hydrogen 3.293 N/A LYS 199.A N SER 194.A O no hydrogen 2.790 N/A LEU 200.A N SER 194.A O no hydrogen 3.153 N/A ASP 201.A N ARG 156.A O no hydrogen 2.756 N/A ALA 202.A N ARG 156.A O no hydrogen 3.320 N/A PHE 203.A N MET 130.A O no hydrogen 2.829 N/A ILE 204.A N GLY 158.A O no hydrogen 2.950 N/A TYR 205.A N SER 128.A O no hydrogen 2.986 N/A TYR 205.A OH GLU 10.A OE2 no hydrogen 2.731 N/A ALA 207.A N GLY 126.A O no hydrogen 2.805 N/A ALA 208.A N THR 125.A OG1 no hydrogen 3.168 N/A VAL 209.A N ASP 206.A OD2 no hydrogen 2.899 N/A LEU 210.A N ASP 206.A O no hydrogen 3.008 N/A ASN 211.A N ALA 207.A O no hydrogen 2.908 N/A TYR 212.A N ALA 208.A O no hydrogen 3.218 N/A LYS 213.A N VAL 209.A O no hydrogen 2.928 N/A LYS 213.A NZ GLU 189.A OE2 no hydrogen 2.992 N/A ALA 214.A N LEU 210.A O no hydrogen 2.936 N/A GLY 215.A N ASN 211.A O no hydrogen 3.013 N/A ARG 216.A NE THR 272.A O no hydrogen 3.052 N/A ARG 216.A NH2 THR 272.A O no hydrogen 2.811 N/A ASP 217.A N ALA 214.A O no hydrogen 3.307 N/A CYS 220.A N ASP 217.A O no hydrogen 2.953 N/A CYS 220.A SG ASP 217.A O no hydrogen 3.659 N/A LEU 222.A N ASP 217.A OD2 no hydrogen 2.760 N/A VAL 223.A N VAL 131.A O no hydrogen 2.857 N/A THR 224.A OG1 ASN 211.A OD1 no hydrogen 3.479 N/A ILE 225.A N VAL 129.A O no hydrogen 2.965 N/A TYR 229.A N ILE 225.A O no hydrogen 3.255 N/A PHE 231.A N ILE 127.A O no hydrogen 2.913 N/A THR 233.A OG1.A THR 125.A O no hydrogen 3.209 N/A THR 234.A N THR 125.A O no hydrogen 3.041 N/A THR 234.A OG1 ILE 108.A O no hydrogen 2.579 N/A GLY 235.A N THR 234.A OG1 no hydrogen 2.699 N/A TYR 236.A N VAL 123.A O no hydrogen 2.823 N/A TYR 236.A OH ASP 206.A OD2 no hydrogen 2.680 N/A GLY 237.A N LEU 106.A O no hydrogen 3.036 N/A ILE 238.A N SER 119.A OG no hydrogen 3.091 N/A ALA 239.A N ALA 102.A O no hydrogen 3.083 N/A LEU 240.A N ASP 117.A O no hydrogen 2.733 N/A GLN 241.A NE2 ALA 99.A O no hydrogen 3.045 N/A LYS 242.A NZ GLU 114.A O no hydrogen 3.420 N/A GLY 243.A N ASP 117.A OD2 no hydrogen 2.790 N/A TRP 246.A N SER 244.A OG no hydrogen 3.376 N/A LYS 247.A NZ PHE 118.A O no hydrogen 3.406 N/A LYS 247.A NZ ASP 251.A OD2 no hydrogen 2.789 N/A ILE 250.A N TRP 246.A O no hydrogen 3.094 N/A ASP 251.A N LYS 247.A O no hydrogen 2.808 N/A LEU 252.A N ARG 248.A O no hydrogen 3.014 N/A ALA 253.A N GLN 249.A O no hydrogen 3.018 N/A LEU 254.A N ILE 250.A O no hydrogen 3.069 N/A LEU 255.A N ASP 251.A O no hydrogen 2.974 N/A GLN 256.A N LEU 252.A O no hydrogen 2.864 N/A PHE 257.A N ALA 253.A O no hydrogen 2.829 N/A VAL 258.A N LEU 254.A O no hydrogen 3.102 N/A GLY 259.A N LEU 255.A O no hydrogen 3.116 N/A ASP 260.A N GLN 256.A O no hydrogen 2.950 N/A GLY 261.A N VAL 258.A O no hydrogen 3.220 N/A GLU 262.A N PHE 257.A O no hydrogen 2.809 N/A MET 263.A N PHE 257.A O no hydrogen 3.295 N/A GLU 265.A N GLY 261.A O no hydrogen 3.407 N/A LEU 266.A N GLU 262.A O no hydrogen 3.241 N/A GLU 267.A N MET 263.A O no hydrogen 2.947 N/A THR 268.A N GLU 264.A O no hydrogen 2.911 N/A THR 268.A OG1 GLU 264.A O no hydrogen 3.162 N/A LEU 269.A N GLU 265.A O no hydrogen 3.016 N/A TRP 270.A N LEU 266.A O no hydrogen 2.836 N/A TRP 270.A NE1 ASP 56.A OD2 no hydrogen 2.763 N/A LEU 271.A N GLU 267.A O no hydrogen 2.923 N/A THR 272.A OG1 THR 268.A O no hydrogen 2.706 N/A CYS 275.A N GLY 215.A O no hydrogen 3.034 N/A CYS 275.A SG ALA 214.A O no hydrogen 3.431 N/A CYS 275.A SG GLY 215.A O no hydrogen 3.659 N/A CYS 275.A SG ASP 217.A O no hydrogen 3.359 N/A