Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5tpz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A N LYS 35.A O no hydrogen 2.348 N/A VAL 5.A N GLN 37.A O no hydrogen 3.036 N/A ASN 6.A ND2 GLN 39.A OE1 no hydrogen 3.269 N/A ASN 6.A ND2 THR 41.A OG1 no hydrogen 3.189 N/A ILE 7.A N GLN 39.A O no hydrogen 2.725 N/A GLY 8.A N ALA 67.A O no hydrogen 2.767 N/A VAL 10.A N LEU 69.A O no hydrogen 2.709 N/A LEU 11.A N VAL 43.A O no hydrogen 2.768 N/A SER 12.A N GLU 247.A OE2 no hydrogen 2.689 N/A THR 13.A OG1 HIS 16.A ND1 no hydrogen 2.524 N/A HIS 16.A N THR 13.A OG1 no hydrogen 3.019 N/A HIS 16.A ND1 THR 13.A OG1 no hydrogen 2.524 N/A GLU 17.A N THR 13.A O no hydrogen 3.245 N/A GLN 18.A N LYS 15.A O no hydrogen 2.755 N/A ILE 19.A N LYS 15.A O no hydrogen 3.093 N/A PHE 20.A N HIS 16.A O no hydrogen 2.794 N/A ARG 21.A N GLU 17.A O no hydrogen 2.874 N/A GLU 22.A N GLN 18.A O no hydrogen 2.756 N/A ALA 23.A N ILE 19.A O no hydrogen 2.928 N/A VAL 24.A N PHE 20.A O no hydrogen 3.117 N/A ASN 25.A N GLU 22.A O no hydrogen 2.670 N/A GLN 26.A N GLU 22.A O no hydrogen 2.930 N/A ALA 27.A N ALA 23.A O no hydrogen 3.137 N/A ASN 28.A N VAL 24.A O no hydrogen 2.895 N/A ASN 28.A ND2 LEU 38.A O no hydrogen 2.603 N/A LYS 29.A N GLN 26.A O no hydrogen 3.245 N/A ARG 30.A N GLN 26.A O no hydrogen 2.819 N/A HIS 31.A N ALA 27.A O no hydrogen 2.967 N/A ARG 34.A N PHE 32.A O no hydrogen 3.217 N/A GLN 37.A N LYS 3.A O no hydrogen 2.530 N/A LEU 38.A N ASN 28.A OD1 no hydrogen 3.142 N/A THR 41.A N ILE 7.A O no hydrogen 2.912 N/A SER 42.A OG GLU 17.A OE1 no hydrogen 2.738 N/A VAL 43.A N ALA 9.A O no hydrogen 2.756 N/A HIS 45.A NE2 SER 71.A OG no hydrogen 2.653 N/A GLN 51.A N ASN 48.A OD1 no hydrogen 2.593 N/A MET 52.A N ASN 48.A O no hydrogen 2.641 N/A ALA 53.A N ALA 49.A O no hydrogen 3.055 N/A LEU 54.A N ILE 50.A O no hydrogen 2.798 N/A SER 55.A N GLN 51.A O no hydrogen 3.080 N/A SER 55.A OG ASP 59.A OD2 no hydrogen 2.214 N/A VAL 56.A N MET 52.A O no hydrogen 3.065 N/A CYS 57.A N ALA 53.A O no hydrogen 3.394 N/A CYS 57.A SG ALA 53.A O no hydrogen 3.947 N/A GLU 58.A N LEU 54.A O no hydrogen 2.771 N/A ASP 59.A N SER 55.A O no hydrogen 2.672 N/A LEU 60.A N VAL 56.A O no hydrogen 3.148 N/A ILE 61.A N VAL 56.A O no hydrogen 2.670 N/A SER 62.A N CYS 57.A O no hydrogen 2.955 N/A SER 62.A OG GLU 58.A O no hydrogen 2.951 N/A SER 63.A N LEU 60.A O no hydrogen 3.051 N/A GLN 64.A N ILE 61.A O no hydrogen 2.620 N/A GLN 64.A NE2 PRO 274.A O no hydrogen 3.233 N/A TYR 66.A N ASN 6.A O no hydrogen 3.144 N/A ILE 68.A N PRO 88.A O no hydrogen 3.109 N/A LEU 69.A N GLY 8.A O no hydrogen 3.029 N/A VAL 70.A N ILE 90.A O no hydrogen 2.651 N/A SER 71.A N VAL 10.A O no hydrogen 3.037 N/A SER 71.A OG VAL 10.A O no hydrogen 3.452 N/A SER 71.A OG HIS 45.A NE2 no hydrogen 2.653 N/A THR 74.A OG1 TYR 99.A OH no hydrogen 2.336 N/A THR 76.A N THR 74.A O no hydrogen 2.535 N/A THR 76.A OG1 TYR 99.A OH no hydrogen 3.269 N/A SER 79.A N PRO 75.A O no hydrogen 2.973 N/A SER 79.A OG HIS 105.A ND1 no hydrogen 2.990 N/A TYR 80.A N THR 76.A O no hydrogen 2.784 N/A THR 81.A N PRO 77.A O no hydrogen 2.961 N/A THR 81.A OG1 PRO 77.A O no hydrogen 2.854 N/A ALA 82.A N ILE 78.A O no hydrogen 3.330 N/A GLY 83.A N SER 79.A O no hydrogen 2.776 N/A PHE 84.A N TYR 80.A O no hydrogen 3.248 N/A TYR 85.A OH ASN 281.A O no hydrogen 2.802 N/A ARG 86.A N GLY 83.A O no hydrogen 3.061 N/A ARG 86.A NH1 GLY 83.A O no hydrogen 3.297 N/A ILE 87.A N ALA 82.A O no hydrogen 3.193 N/A VAL 89.A N SER 107.A O no hydrogen 3.063 N/A ILE 90.A N ILE 68.A O no hydrogen 2.699 N/A GLY 91.A N LEU 109.A O no hydrogen 2.562 N/A LEU 92.A N VAL 70.A O no hydrogen 2.875 N/A THR 93.A OG1 SER 71.A O no hydrogen 3.146 N/A ARG 95.A NE PRO 113.A O no hydrogen 2.594 N/A ARG 95.A NH1 GLU 221.A OE1 no hydrogen 3.138 N/A SER 97.A N GLU 143.A OE1 no hydrogen 2.698 N/A SER 97.A OG GLU 143.A OE1 no hydrogen 3.043 N/A SER 97.A OG GLU 143.A OE2 no hydrogen 3.429 N/A TYR 99.A N MET 96.A O no hydrogen 3.262 N/A TYR 99.A OH THR 74.A OG1 no hydrogen 2.336 N/A TYR 99.A OH THR 76.A OG1 no hydrogen 3.269 N/A SER 100.A N SER 97.A O no hydrogen 2.863 N/A SER 100.A OG ASP 315.A OD1 no hydrogen 2.604 N/A SER 100.A OG ASP 315.A OD2 no hydrogen 2.808 N/A ASP 101.A N ILE 98.A O no hydrogen 3.090 N/A ILE 104.A N ASP 101.A O no hydrogen 3.078 N/A HIS 105.A N ASP 101.A O no hydrogen 3.041 N/A HIS 105.A ND1 SER 79.A OG no hydrogen 2.990 N/A SER 107.A OG ILE 87.A O no hydrogen 3.297 N/A LEU 109.A N VAL 89.A O no hydrogen 2.673 N/A ARG 110.A N GLY 314.A O no hydrogen 3.044 N/A ARG 110.A NE ASP 315.A OD1 no hydrogen 2.936 N/A ARG 110.A NH1 THR 94.A O no hydrogen 2.793 N/A ARG 110.A NH1 MET 96.A O no hydrogen 2.977 N/A ARG 110.A NH2 MET 96.A O no hydrogen 2.576 N/A ARG 110.A NH2 SER 100.A OG no hydrogen 2.961 N/A THR 111.A N GLY 91.A O no hydrogen 2.984 N/A THR 111.A OG1 GLY 91.A O no hydrogen 3.374 N/A THR 111.A OG1 LEU 92.A O no hydrogen 3.075 N/A THR 111.A OG1 HIS 250.A ND1 no hydrogen 3.165 N/A TYR 115.A N ARG 95.A O no hydrogen 2.937 N/A SER 116.A N SER 97.A OG no hydrogen 3.237 N/A SER 116.A OG SER 97.A OG no hydrogen 3.377 N/A HIS 117.A N PRO 114.A O no hydrogen 2.812 N/A GLN 118.A N TYR 115.A O no hydrogen 2.798 N/A GLN 118.A NE2 TYR 115.A O no hydrogen 3.381 N/A ALA 119.A N SER 116.A O no hydrogen 2.969 N/A LEU 120.A N HIS 117.A O no hydrogen 2.774 N/A TRP 122.A N GLN 118.A O no hydrogen 2.994 N/A TRP 122.A NE1 VAL 219.A O no hydrogen 2.821 N/A PHE 123.A N ALA 119.A O no hydrogen 2.684 N/A GLU 124.A N LEU 120.A O no hydrogen 2.904 N/A MET 125.A N VAL 121.A O no hydrogen 2.673 N/A MET 126.A N TRP 122.A O no hydrogen 3.169 N/A ARG 127.A N PHE 123.A O no hydrogen 3.045 N/A LEU 128.A N GLU 124.A O no hydrogen 3.027 N/A PHE 129.A N MET 125.A O no hydrogen 3.004 N/A TRP 131.A N MET 126.A O no hydrogen 2.971 N/A VAL 134.A N ALA 161.A O no hydrogen 3.196 N/A ILE 135.A N VAL 188.A O no hydrogen 3.115 N/A LEU 136.A N LYS 163.A O no hydrogen 2.789 N/A ILE 137.A N ILE 190.A O no hydrogen 2.874 N/A VAL 138.A N LEU 165.A O no hydrogen 3.188 N/A SER 139.A N SER 192.A O no hydrogen 2.913 N/A SER 139.A OG ASP 141.A OD1 no hydrogen 2.541 N/A SER 139.A OG SER 192.A O no hydrogen 3.240 N/A ASP 140.A N PHE 167.A O no hydrogen 2.836 N/A GLU 143.A N ASP 141.A OD2 no hydrogen 2.794 N/A GLY 144.A N ASP 141.A OD1 no hydrogen 3.273 N/A ARG 145.A N ASP 141.A O no hydrogen 2.853 N/A ALA 146.A N HIS 142.A O no hydrogen 2.643 N/A ALA 147.A N GLU 143.A O no hydrogen 3.194 N/A GLN 148.A N GLY 144.A O no hydrogen 3.011 N/A GLN 148.A NE2 GLU 152.A OE1 no hydrogen 3.483 N/A GLN 148.A NE2 GLU 152.A OE2 no hydrogen 3.407 N/A LYS 149.A N ARG 145.A O no hydrogen 2.964 N/A LYS 150.A N ALA 146.A O no hydrogen 3.381 N/A LYS 150.A NZ HIS 117.A ND1 no hydrogen 3.218 N/A LEU 151.A N ALA 147.A O no hydrogen 3.193 N/A GLU 152.A N GLN 148.A O no hydrogen 3.070 N/A THR 153.A N LYS 149.A O no hydrogen 2.757 N/A THR 153.A OG1 LYS 149.A O no hydrogen 3.036 N/A LEU 154.A N LYS 150.A O no hydrogen 3.115 N/A LEU 155.A N LEU 151.A O no hydrogen 3.120 N/A LEU 155.A N GLU 152.A O no hydrogen 2.776 N/A GLU 156.A N THR 153.A O no hydrogen 3.166 N/A ASP 162.A N PRO 159.A O no hydrogen 3.365 N/A LYS 163.A N VAL 134.A O no hydrogen 3.159 N/A LEU 165.A N LEU 136.A O no hydrogen 2.830 N/A GLN 166.A NE2 ASP 140.A OD1 no hydrogen 3.171 N/A PHE 167.A N VAL 138.A O no hydrogen 3.139 N/A GLY 170.A N ASP 197.A OD1 no hydrogen 3.195 N/A GLY 170.A N ASP 197.A OD2 no hydrogen 3.140 N/A THR 171.A N GLU 168.A O no hydrogen 3.112 N/A THR 171.A OG1 GLU 168.A O no hydrogen 2.264 N/A LEU 174.A N SER 204.A OG no hydrogen 3.355 N/A THR 175.A OG1 ASN 173.A OD1 no hydrogen 2.808 N/A LEU 178.A N LEU 174.A O no hydrogen 2.891 N/A LEU 179.A N THR 175.A O no hydrogen 2.438 N/A GLU 180.A N ALA 176.A O no hydrogen 3.021 N/A ALA 181.A N LEU 177.A O no hydrogen 2.707 N/A LYS 182.A N LEU 178.A O no hydrogen 2.563 N/A GLU 183.A N LEU 179.A O no hydrogen 2.925 N/A LEU 184.A N GLU 180.A O no hydrogen 2.903 N/A GLU 185.A N ALA 181.A O no hydrogen 3.062 N/A ILE 189.A N VAL 216.A O no hydrogen 3.175 N/A ILE 190.A N ILE 135.A O no hydrogen 2.836 N/A LEU 191.A N LEU 218.A O no hydrogen 3.112 N/A SER 192.A N ILE 137.A O no hydrogen 2.838 N/A ALA 193.A N GLU 223.A OE1 no hydrogen 3.182 N/A ASP 197.A N SER 194.A OG no hydrogen 3.194 N/A ALA 198.A N SER 194.A O no hydrogen 2.693 N/A THR 199.A N GLU 195.A O no hydrogen 2.846 N/A THR 199.A OG1 GLU 195.A O no hydrogen 2.826 N/A VAL 201.A N ASP 197.A O no hydrogen 3.210 N/A TYR 202.A N ALA 198.A O no hydrogen 2.637 N/A TYR 202.A OH GLU 223.A O no hydrogen 2.415 N/A LYS 203.A N THR 199.A O no hydrogen 2.863 N/A SER 204.A N ALA 200.A O no hydrogen 3.019 N/A SER 204.A OG ALA 200.A O no hydrogen 3.118 N/A ALA 205.A N VAL 201.A O no hydrogen 2.918 N/A ALA 206.A N LYS 203.A O no hydrogen 2.550 N/A MET 207.A N LYS 203.A O no hydrogen 3.152 N/A LEU 208.A N ALA 205.A O no hydrogen 3.422 N/A MET 210.A N ALA 205.A O no hydrogen 3.069 N/A VAL 216.A N ARG 187.A O no hydrogen 2.835 N/A TRP 217.A NE1 MET 210.A O no hydrogen 3.122 N/A LEU 218.A N ILE 189.A O no hydrogen 2.989 N/A GLU 223.A N GLU 223.A OE2 no hydrogen 2.611 N/A ILE 224.A N GLU 221.A O no hydrogen 3.221 N/A SER 225.A N ARG 222.A O no hydrogen 2.765 N/A SER 227.A OG GLY 226.A O no hydrogen 2.429 N/A ALA 228.A N SER 225.A O no hydrogen 3.107 N/A ALA 232.A N LEU 229.A O no hydrogen 3.216 N/A GLY 235.A N LEU 326.A O no hydrogen 2.967 N/A ILE 236.A N PRO 233.A O no hydrogen 3.089 N/A ILE 237.A N TRP 217.A O no hydrogen 2.602 N/A GLY 238.A N MET 324.A O no hydrogen 2.798 N/A LEU 239.A N GLY 220.A O no hydrogen 3.088 N/A GLN 240.A N SER 322.A O no hydrogen 3.119 N/A ILE 242.A N GLN 320.A O no hydrogen 2.851 N/A GLY 244.A N LEU 241.A O no hydrogen 3.361 N/A ASN 246.A ND2 ASN 243.A OD1 no hydrogen 3.553 N/A GLU 247.A N LYS 245.A O no hydrogen 3.035 N/A ALA 249.A N ASN 246.A OD1 no hydrogen 2.971 N/A HIS 250.A N ASN 246.A O no hydrogen 2.951 N/A HIS 250.A NE2 ASN 243.A O no hydrogen 3.113 N/A ILE 251.A N GLU 247.A O no hydrogen 2.941 N/A SER 252.A N SER 248.A O no hydrogen 3.131 N/A SER 252.A OG ASP 253.A OD1 no hydrogen 3.052 N/A ASP 253.A N ALA 249.A O no hydrogen 3.448 N/A ALA 254.A N HIS 250.A O no hydrogen 2.966 N/A VAL 255.A N ILE 251.A O no hydrogen 3.272 N/A ALA 256.A N SER 252.A O no hydrogen 3.167 N/A VAL 257.A N ASP 253.A O no hydrogen 2.935 N/A VAL 258.A N ALA 254.A O no hydrogen 2.694 N/A ALA 259.A N VAL 255.A O no hydrogen 2.717 N/A GLN 260.A N ALA 256.A O no hydrogen 2.795 N/A ALA 261.A N VAL 257.A O no hydrogen 2.919 N/A ILE 262.A N VAL 258.A O no hydrogen 2.447 N/A HIS 263.A N ALA 259.A O no hydrogen 3.047 N/A GLU 264.A N GLN 260.A O no hydrogen 2.972 N/A LEU 265.A N ALA 261.A O no hydrogen 3.024 N/A LEU 265.A N ILE 262.A O no hydrogen 3.129 N/A PHE 266.A N HIS 263.A O no hydrogen 3.117 N/A GLU 267.A N GLU 264.A O no hydrogen 3.520 N/A MET 268.A N LEU 265.A O no hydrogen 3.268 N/A THR 272.A N THR 287.A OG1 no hydrogen 3.025 N/A ASN 281.A N CYS 278.A O no hydrogen 3.174 N/A TRP 285.A N TYR 85.A O no hydrogen 2.735 N/A TRP 285.A NE1 THR 272.A O no hydrogen 2.756 N/A THR 287.A OG1 THR 272.A O no hydrogen 3.370 N/A PHE 291.A N THR 287.A O no hydrogen 2.812 N/A LYS 292.A N GLY 288.A O no hydrogen 3.005 N/A ARG 293.A N PRO 289.A O no hydrogen 3.045 N/A VAL 294.A N LEU 290.A O no hydrogen 2.973 N/A VAL 294.A N PHE 291.A O no hydrogen 2.837 N/A LEU 295.A N PHE 291.A O no hydrogen 3.089 N/A MET 296.A N LYS 292.A O no hydrogen 3.119 N/A SER 297.A N ARG 293.A O no hydrogen 3.215 N/A SER 297.A OG ARG 293.A O no hydrogen 2.654 N/A SER 298.A N LEU 295.A O no hydrogen 2.961 N/A SER 298.A OG VAL 294.A O no hydrogen 3.245 N/A TYR 300.A N ILE 308.A O no hydrogen 3.315 N/A VAL 304.A N ASP 253.A OD1 no hydrogen 2.598 N/A THR 305.A N ASP 253.A OD2 no hydrogen 2.662 N/A THR 305.A OG1 ASP 253.A OD2 no hydrogen 2.743 N/A GLY 306.A N GLY 303.A O no hydrogen 2.787 N/A ILE 308.A N TYR 300.A O no hydrogen 2.966 N/A ASN 311.A N ASP 315.A O no hydrogen 3.196 N/A GLY 314.A N ASN 311.A O no hydrogen 3.047 N/A ASP 315.A N ASN 311.A OD1 no hydrogen 2.678 N/A ARG 316.A NE THR 111.A O no hydrogen 3.326 N/A LYS 317.A N GLU 309.A O no hydrogen 3.132 N/A TYR 321.A N PHE 337.A O no hydrogen 3.389 N/A SER 322.A N GLN 240.A O no hydrogen 2.659 N/A SER 322.A OG GLN 240.A O no hydrogen 3.021 N/A ILE 323.A N GLY 335.A O no hydrogen 2.760 N/A MET 324.A N GLY 238.A O no hydrogen 3.314 N/A ASN 325.A N VAL 332.A O no hydrogen 2.966 N/A ASN 325.A ND2 ILE 350.A O no hydrogen 3.536 N/A LEU 326.A N ILE 236.A O no hydrogen 3.371 N/A GLN 327.A N LYS 330.A O no hydrogen 3.010 N/A ASN 328.A N ASP 234.A OD1 no hydrogen 3.342 N/A LYS 330.A N GLN 327.A O no hydrogen 2.840 N/A ILE 336.A N ILE 343.A O no hydrogen 2.828 N/A PHE 337.A N TYR 321.A O no hydrogen 2.856 N/A ASN 338.A N TYR 341.A O no hydrogen 2.813 N/A SER 340.A N ASN 338.A OD1 no hydrogen 2.946 N/A SER 340.A OG ASN 338.A OD1 no hydrogen 2.838 N/A TYR 341.A N ASN 338.A OD1 no hydrogen 2.495 N/A ILE 343.A N ILE 336.A O no hydrogen 2.772 N/A ASN 345.A N VAL 334.A O no hydrogen 2.486 N/A ILE 350.A N ASN 325.A OD1 no hydrogen 2.961 N/A