Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5tx3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 43.A OD2 no hydrogen 2.401 N/A GLY 2.A N SER 1.A OG no hydrogen 2.273 N/A LYS 5.A N SER 3.A OG no hydrogen 3.028 N/A ASP 8.A N LYS 5.A O no hydrogen 3.401 N/A LEU 11.A N TYR 7.A O no hydrogen 2.921 N/A TYR 13.A N LEU 10.A O no hydrogen 2.835 N/A TYR 14.A N LEU 10.A O no hydrogen 2.970 N/A TYR 14.A OH HIS 66.A ND1 no hydrogen 2.761 N/A GLU 15.A N CYS 29.A O no hydrogen 2.995 N/A HIS 17.A N LEU 27.A O no hydrogen 2.755 N/A GLU 18.A N GLU 18.A OE1 no hydrogen 2.788 N/A ILE 20.A N VAL 25.A O no hydrogen 2.516 N/A LYS 24.A N ILE 41.A O no hydrogen 2.952 N/A VAL 25.A N ILE 20.A O no hydrogen 2.966 N/A LYS 26.A N ILE 39.A O no hydrogen 2.842 N/A LYS 26.A NZ THR 19.A OG1 no hydrogen 2.197 N/A LEU 27.A N GLU 18.A O no hydrogen 3.124 N/A ALA 28.A N VAL 37.A O no hydrogen 3.047 N/A CYS 29.A N GLU 15.A O no hydrogen 3.059 N/A CYS 29.A SG GLY 34.A O no hydrogen 3.414 N/A HIS 30.A N GLU 35.A O no hydrogen 3.025 N/A HIS 30.A ND1 THR 33.A OG1 no hydrogen 2.578 N/A ILE 31.A N TYR 13.A O no hydrogen 2.862 N/A THR 33.A N HIS 30.A ND1 no hydrogen 3.273 N/A THR 33.A N HIS 30.A O no hydrogen 3.022 N/A THR 33.A OG1 HIS 30.A ND1 no hydrogen 2.578 N/A GLY 34.A N HIS 30.A O no hydrogen 2.519 N/A VAL 37.A N ALA 28.A O no hydrogen 2.912 N/A ALA 38.A N LEU 78.A O no hydrogen 2.962 N/A ILE 39.A N LYS 26.A O no hydrogen 2.599 N/A LYS 40.A N MET 76.A O no hydrogen 2.865 N/A ILE 41.A N LYS 24.A O no hydrogen 2.683 N/A MET 42.A N ILE 74.A O no hydrogen 3.017 N/A LYS 44.A NZ THR 70.A O no hydrogen 2.527 N/A ILE 50.A N LYS 47.A O no hydrogen 3.295 N/A ALA 52.A N THR 48.A O no hydrogen 3.029 N/A LYS 54.A N ILE 50.A O no hydrogen 3.122 N/A ASN 55.A N ALA 52.A O no hydrogen 3.117 N/A LEU 56.A N LEU 53.A O no hydrogen 3.368 N/A ARG 57.A N TYR 114.A OH no hydrogen 3.183 N/A ARG 57.A NH1 PRO 251.A O no hydrogen 3.428 N/A ARG 57.A NH2 TYR 283.A OH no hydrogen 2.664 N/A HIS 58.A NE2 TRP 246.A O no hydrogen 2.934 N/A GLN 59.A N GLN 59.A OE1 no hydrogen 2.389 N/A GLN 59.A NE2 GLN 247.A O no hydrogen 3.391 N/A HIS 60.A N HIS 58.A ND1 no hydrogen 3.104 N/A ILE 61.A N HIS 58.A O no hydrogen 2.809 N/A CYS 62.A N LEU 140.A O no hydrogen 2.939 N/A CYS 62.A SG GLU 79.A O no hydrogen 3.693 N/A GLN 63.A N GLU 79.A OE1 no hydrogen 3.330 N/A GLN 63.A NE2 LEU 64.A O no hydrogen 3.092 N/A TYR 65.A N VAL 77.A O no hydrogen 2.971 N/A HIS 66.A ND1 TYR 14.A OH no hydrogen 2.761 N/A VAL 67.A N TYR 283.A O no hydrogen 2.900 N/A LEU 68.A N PHE 75.A O no hydrogen 3.080 N/A THR 70.A N LYS 73.A O no hydrogen 2.959 N/A ASN 72.A N THR 70.A OG1 no hydrogen 2.985 N/A LYS 73.A N THR 70.A OG1 no hydrogen 2.871 N/A LYS 73.A NZ ASP 43.A OD2 no hydrogen 2.906 N/A ILE 74.A N MET 42.A O no hydrogen 2.992 N/A PHE 75.A N LEU 68.A O no hydrogen 2.785 N/A MET 76.A N LYS 40.A O no hydrogen 2.965 N/A VAL 77.A N HIS 66.A O no hydrogen 2.908 N/A LEU 78.A N ALA 38.A O no hydrogen 2.878 N/A GLU 79.A N GLN 63.A O no hydrogen 2.998 N/A CYS 81.A SG GLU 79.A O no hydrogen 4.017 N/A GLY 83.A N PHE 132.A O no hydrogen 2.731 N/A LEU 86.A N LEU 130.A O no hydrogen 2.703 N/A PHE 87.A N PRO 127.A O no hydrogen 2.821 N/A TYR 89.A N GLU 85.A O no hydrogen 3.329 N/A TYR 89.A OH GLU 100.A OE2 no hydrogen 2.939 N/A ILE 90.A N LEU 86.A O no hydrogen 2.918 N/A ILE 91.A N PHE 87.A O no hydrogen 3.144 N/A SER 92.A N ASP 88.A O no hydrogen 2.775 N/A GLN 93.A N TYR 89.A O no hydrogen 3.209 N/A GLN 93.A N ILE 90.A O no hydrogen 3.248 N/A ASP 94.A N ILE 91.A O no hydrogen 3.385 N/A ARG 95.A N GLN 93.A O no hydrogen 2.639 N/A LEU 96.A N LEU 175.A O no hydrogen 2.922 N/A SER 97.A OG GLU 99.A OE1 no hydrogen 3.353 N/A GLU 99.A N GLU 99.A OE1 no hydrogen 2.565 N/A GLU 100.A N SER 97.A OG no hydrogen 3.142 N/A THR 101.A N SER 97.A O no hydrogen 2.814 N/A THR 101.A OG1 SER 97.A O no hydrogen 2.622 N/A ARG 102.A N GLU 98.A O no hydrogen 2.858 N/A ARG 102.A NH2 GLU 98.A OE2 no hydrogen 3.358 N/A VAL 103.A N GLU 99.A O no hydrogen 3.175 N/A VAL 104.A N GLU 100.A O no hydrogen 2.987 N/A PHE 105.A N THR 101.A O no hydrogen 2.535 N/A ARG 106.A N ARG 102.A O no hydrogen 2.896 N/A ARG 106.A NH1 ILE 236.A O no hydrogen 2.443 N/A ARG 106.A NH1 TYR 242.A O no hydrogen 3.327 N/A ARG 106.A NH2 TYR 242.A O no hydrogen 2.564 N/A GLN 107.A N VAL 104.A O no hydrogen 2.871 N/A GLN 107.A NE2 HIS 60.A NE2 no hydrogen 2.856 N/A ILE 108.A N VAL 104.A O no hydrogen 3.105 N/A VAL 109.A N PHE 105.A O no hydrogen 2.981 N/A SER 110.A N ARG 106.A O no hydrogen 2.989 N/A SER 110.A OG HIS 58.A NE2 no hydrogen 3.113 N/A SER 110.A OG GLU 245.A O no hydrogen 3.383 N/A ALA 111.A N GLN 107.A O no hydrogen 3.158 N/A VAL 112.A N ILE 108.A O no hydrogen 3.108 N/A ALA 113.A N VAL 109.A O no hydrogen 2.657 N/A TYR 114.A N SER 110.A O no hydrogen 2.966 N/A VAL 115.A N ALA 111.A O no hydrogen 2.813 N/A HIS 116.A N VAL 112.A O no hydrogen 3.191 N/A HIS 116.A NE2 ASP 164.A OD2 no hydrogen 2.623 N/A SER 117.A N ALA 113.A O no hydrogen 3.120 N/A SER 117.A OG ALA 113.A O no hydrogen 3.375 N/A GLN 118.A N TYR 114.A O no hydrogen 3.316 N/A GLN 118.A N VAL 115.A O no hydrogen 3.149 N/A GLY 119.A N HIS 116.A O no hydrogen 2.606 N/A TYR 120.A N VAL 115.A O no hydrogen 3.159 N/A HIS 122.A N ASP 164.A OD2 no hydrogen 3.073 N/A ARG 123.A N ASP 164.A OD1 no hydrogen 3.097 N/A ASP 124.A N HIS 122.A ND1 no hydrogen 2.939 N/A ASN 129.A N LYS 126.A O no hydrogen 2.986 N/A ASN 129.A ND2 ASP 124.A O no hydrogen 3.296 N/A LEU 131.A N LYS 139.A O no hydrogen 2.956 N/A PHE 132.A N GLY 84.A O no hydrogen 2.921 N/A ASP 133.A N LYS 137.A O no hydrogen 2.811 N/A GLU 134.A N GLU 134.A OE1 no hydrogen 2.621 N/A HIS 136.A N ASP 133.A O no hydrogen 3.146 N/A LYS 137.A N ASP 133.A OD1 no hydrogen 2.917 N/A LYS 139.A N LEU 131.A O no hydrogen 2.765 N/A LYS 139.A NZ GLN 59.A O no hydrogen 3.245 N/A LYS 139.A NZ GLU 79.A OE1 no hydrogen 3.228 N/A LYS 139.A NZ GLU 79.A OE2 no hydrogen 2.868 N/A LEU 140.A N HIS 60.A O no hydrogen 2.690 N/A ILE 141.A N ASN 129.A O no hydrogen 2.990 N/A GLY 144.A N ASP 142.A OD1 no hydrogen 2.770 N/A ALA 151.A N LEU 148.A O no hydrogen 2.871 N/A LEU 155.A N ALA 152.A O no hydrogen 3.065 N/A ILE 156.A N ALA 152.A O no hydrogen 3.358 N/A GLN 157.A N PRO 153.A O no hydrogen 3.201 N/A GLN 157.A N GLU 154.A O no hydrogen 3.237 N/A GLY 158.A N GLU 154.A O no hydrogen 3.122 N/A SER 161.A OG HIS 116.A ND1 no hydrogen 3.312 N/A ALA 163.A N GLY 160.A O no hydrogen 3.287 N/A TRP 166.A N GLU 162.A O no hydrogen 3.123 N/A SER 167.A N ALA 163.A O no hydrogen 3.220 N/A SER 167.A OG TYR 150.A O no hydrogen 2.739 N/A SER 167.A OG ALA 163.A O no hydrogen 3.447 N/A MET 168.A N ASP 164.A O no hydrogen 2.988 N/A GLY 169.A N VAL 165.A O no hydrogen 2.962 N/A ILE 170.A N TRP 166.A O no hydrogen 3.045 N/A LEU 171.A N SER 167.A O no hydrogen 2.850 N/A LEU 172.A N MET 168.A O no hydrogen 2.942 N/A TYR 173.A N GLY 169.A O no hydrogen 2.919 N/A TYR 173.A OH ASP 200.A O no hydrogen 3.112 N/A VAL 174.A N ILE 170.A O no hydrogen 2.970 N/A LEU 175.A N LEU 171.A O no hydrogen 2.682 N/A MET 176.A N LEU 172.A O no hydrogen 3.145 N/A CYS 177.A N TYR 173.A O no hydrogen 2.694 N/A GLY 178.A N VAL 174.A O no hydrogen 2.722 N/A ALA 189.A N ASN 186.A OD1 no hydrogen 3.436 N/A LEU 190.A N ASN 186.A O no hydrogen 2.999 N/A TYR 191.A N VAL 187.A O no hydrogen 2.912 N/A LYS 192.A N MET 188.A O no hydrogen 3.171 N/A LYS 193.A N ALA 189.A O no hydrogen 2.881 N/A LYS 193.A NZ ASP 183.A O no hydrogen 2.636 N/A ILE 194.A N LEU 190.A O no hydrogen 3.214 N/A MET 195.A N TYR 191.A O no hydrogen 3.117 N/A ARG 196.A N LYS 192.A O no hydrogen 2.939 N/A GLY 197.A N LYS 193.A O no hydrogen 2.967 N/A TRP 204.A NE1 MET 176.A O no hydrogen 2.926 N/A LEU 205.A N PRO 202.A O no hydrogen 2.916 N/A SER 206.A OG GLU 98.A OE1 no hydrogen 3.210 N/A SER 206.A OG GLU 98.A OE2 no hydrogen 3.370 N/A SER 206.A OG SER 209.A OG no hydrogen 3.094 N/A SER 209.A N SER 206.A OG no hydrogen 3.074 N/A SER 209.A OG GLU 98.A OE1 no hydrogen 2.673 N/A SER 209.A OG SER 206.A OG no hydrogen 3.094 N/A ILE 210.A N SER 206.A O no hydrogen 3.036 N/A LEU 211.A N PRO 207.A O no hydrogen 2.776 N/A LEU 212.A N SER 208.A O no hydrogen 2.980 N/A LEU 213.A N SER 209.A O no hydrogen 2.876 N/A GLN 214.A N ILE 210.A O no hydrogen 2.979 N/A GLN 215.A N LEU 211.A O no hydrogen 2.920 N/A MET 216.A N LEU 212.A O no hydrogen 2.855 N/A MET 216.A N LEU 213.A O no hydrogen 3.250 N/A LEU 217.A N LEU 213.A O no hydrogen 2.781 N/A GLN 218.A NE2 GLN 214.A O no hydrogen 3.254 N/A LYS 222.A N ASP 220.A OD1 no hydrogen 2.801 N/A LYS 223.A N ASP 220.A O no hydrogen 3.200 N/A LYS 223.A N ASP 220.A OD1 no hydrogen 3.225 N/A ARG 224.A N PRO 221.A O no hydrogen 3.223 N/A ARG 224.A NE GLN 218.A O no hydrogen 2.876 N/A ARG 224.A NH1 GLU 154.A OE2 no hydrogen 2.917 N/A ARG 224.A NH1 GLU 162.A O no hydrogen 3.035 N/A ARG 224.A NH2 GLU 154.A OE2 no hydrogen 2.863 N/A ARG 224.A NH2 GLN 218.A O no hydrogen 2.969 N/A ILE 225.A N GLN 215.A O no hydrogen 2.832 N/A SER 226.A OG ASN 229.A OD1 no hydrogen 3.031 N/A ASN 229.A N SER 226.A OG no hydrogen 3.383 N/A LEU 230.A N SER 226.A O no hydrogen 2.962 N/A LEU 231.A N MET 227.A O no hydrogen 3.271 N/A LEU 231.A N LYS 228.A O no hydrogen 3.350 N/A HIS 233.A N LEU 230.A O no hydrogen 3.483 N/A HIS 233.A NE2 GLN 215.A OE1 no hydrogen 2.623 N/A TRP 235.A N HIS 233.A ND1 no hydrogen 3.099 N/A MET 237.A N HIS 233.A O no hydrogen 2.998 N/A MET 237.A N PRO 234.A O no hydrogen 3.280 N/A GLN 238.A N TRP 235.A O no hydrogen 3.241 N/A TYR 240.A N MET 237.A O no hydrogen 2.821 N/A ASN 241.A N MET 237.A O no hydrogen 2.872 N/A VAL 244.A N LEU 231.A O no hydrogen 2.937 N/A GLN 247.A N GLN 247.A OE1 no hydrogen 2.825 N/A SER 248.A OG ARG 57.A O no hydrogen 2.288 N/A SER 248.A OG ASN 250.A O no hydrogen 3.001 N/A LYS 249.A N GLN 59.A OE1 no hydrogen 3.418 N/A ASN 250.A N SER 248.A OG no hydrogen 3.365 N/A CYS 259.A N ASP 256.A OD2 no hydrogen 2.714 N/A CYS 259.A SG ASP 256.A OD2 no hydrogen 3.365 N/A VAL 260.A N ASP 256.A O no hydrogen 2.863 N/A THR 261.A N ASP 257.A O no hydrogen 3.013 N/A THR 261.A OG1 ASP 257.A O no hydrogen 3.099 N/A THR 261.A OG1 ASP 258.A O no hydrogen 2.661 N/A LEU 263.A N CYS 259.A O no hydrogen 3.194 N/A SER 264.A N VAL 260.A O no hydrogen 2.888 N/A SER 264.A N THR 261.A O no hydrogen 3.071 N/A SER 264.A OG VAL 260.A O no hydrogen 2.521 N/A VAL 265.A N THR 261.A O no hydrogen 3.199 N/A HIS 266.A N GLU 262.A O no hydrogen 3.376 N/A HIS 267.A N LEU 263.A O no hydrogen 3.075 N/A HIS 267.A ND1 LEU 263.A O no hydrogen 3.147 N/A ASN 269.A N SER 264.A O no hydrogen 3.192 N/A ARG 271.A NE GLU 275.A OE2 no hydrogen 2.784 N/A GLN 272.A NE2 ASP 276.A OD2 no hydrogen 3.549 N/A THR 273.A N ASN 270.A OD1 no hydrogen 2.762 N/A THR 273.A OG1 ASN 270.A OD1 no hydrogen 3.075 N/A MET 274.A N ASN 270.A O no hydrogen 3.117 N/A GLU 275.A N ARG 271.A O no hydrogen 3.246 N/A ASP 276.A N GLN 272.A O no hydrogen 2.963 N/A LEU 277.A N THR 273.A O no hydrogen 2.889 N/A ILE 278.A N MET 274.A O no hydrogen 2.803 N/A SER 279.A N GLU 275.A O no hydrogen 3.006 N/A SER 279.A OG GLU 275.A O no hydrogen 3.009 N/A LEU 280.A N LEU 277.A O no hydrogen 3.455 N/A TRP 281.A N ILE 278.A O no hydrogen 3.167 N/A TRP 281.A NE1 PHE 252.A O no hydrogen 2.849 N/A TYR 283.A N THR 287.A OG1 no hydrogen 2.830 N/A TYR 283.A OH LYS 54.A O no hydrogen 2.597 N/A ALA 288.A N ASP 284.A O no hydrogen 3.189 N/A THR 289.A N HIS 285.A O no hydrogen 2.855 N/A THR 289.A N LEU 286.A O no hydrogen 3.133 N/A THR 289.A OG1 HIS 285.A O no hydrogen 2.472 N/A TYR 290.A N LEU 286.A O no hydrogen 2.980 N/A LEU 291.A N THR 287.A O no hydrogen 2.956 N/A LEU 292.A N ALA 288.A O no hydrogen 3.089 N/A LEU 293.A N THR 289.A O no hydrogen 2.946 N/A LEU 294.A N TYR 290.A O no hydrogen 3.009 N/A ALA 295.A N LEU 291.A O no hydrogen 3.131 N/A LYS 296.A N LEU 292.A O no hydrogen 3.010 N/A LYS 296.A NZ PRO 302.A O no hydrogen 3.024 N/A LYS 297.A N LEU 293.A O no hydrogen 2.697 N/A LYS 297.A NZ ASP 256.A OD1 no hydrogen 3.566 N/A ALA 298.A N LEU 294.A O no hydrogen 2.656 N/A ARG 299.A NH1 GLU 35.A OE1 no hydrogen 3.196 N/A ARG 299.A NH1 GLU 35.A OE2 no hydrogen 3.237 N/A ARG 299.A NH2 GLU 35.A OE1 no hydrogen 2.993 N/A GLY 300.A N LYS 297.A O no hydrogen 2.446 N/A ARG 304.A NH1 GLU 262.A OE1 no hydrogen 3.556 N/A ARG 306.A N LEU 32.A O no hydrogen 2.599 N/A