Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5u2t_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N GLN 3.A O no hydrogen 3.067 N/A ASN 7.A ND2 HIS 46.A O no hydrogen 2.821 N/A THR 11.A N ASN 7.A O no hydrogen 2.942 N/A THR 11.A OG1.A ASN 7.A O no hydrogen 3.242 N/A THR 11.A OG1.B ASN 7.A O no hydrogen 3.408 N/A THR 11.A OG1.B GLY 8.A O no hydrogen 3.511 N/A ASP 12.A N GLY 8.A O no hydrogen 2.895 N/A MET 13.A N GLY 9.A O no hydrogen 3.068 N/A LEU 14.A N ILE 10.A O no hydrogen 2.931 N/A THR 15.A N THR 11.A O no hydrogen 2.942 N/A THR 15.A OG1 THR 11.A O no hydrogen 3.034 N/A GLU 16.A N ASP 12.A O no hydrogen 3.047 N/A LEU 17.A N MET 13.A O no hydrogen 2.951 N/A ALA 18.A N LEU 14.A O no hydrogen 2.858 N/A ASN 19.A N THR 15.A O no hydrogen 2.966 N/A PHE 20.A N GLU 16.A O no hydrogen 3.110 N/A GLU 21.A N LEU 17.A O no hydrogen 3.020 N/A LYS 22.A N ALA 18.A O no hydrogen 2.996 N/A LYS 22.A NZ ASN 23.A OD1 no hydrogen 3.029 N/A ASN 23.A N ASN 19.A O no hydrogen 2.839 N/A ASN 23.A ND2 ASN 93.A OD1 no hydrogen 2.895 N/A VAL 24.A N PHE 20.A O no hydrogen 2.918 N/A SER 25.A N PHE 20.A O no hydrogen 3.034 N/A SER 25.A OG GLU 21.A OE1 no hydrogen 3.493 N/A ALA 27.A N GLU 21.A O no hydrogen 2.871 N/A TYR 31.A N ALA 27.A O no hydrogen 3.001 N/A ASN 32.A N ILE 28.A O no hydrogen 2.981 N/A ALA 33.A N HIS 29.A O no hydrogen 2.929 N/A TYR 34.A N LYS 30.A O no hydrogen 2.962 N/A ARG 35.A N TYR 31.A O no hydrogen 2.937 N/A LYS 36.A N ASN 32.A O no hydrogen 2.870 N/A ALA 37.A N ALA 33.A O no hydrogen 3.006 N/A ALA 38.A N TYR 34.A O no hydrogen 2.889 N/A SER 39.A N ARG 35.A O no hydrogen 2.887 N/A VAL 40.A N LYS 36.A O no hydrogen 3.001 N/A ILE 41.A N ALA 37.A O no hydrogen 2.965 N/A ALA 42.A N ALA 38.A O no hydrogen 2.805 N/A LYS 43.A N SER 39.A O no hydrogen 3.264 N/A TYR 44.A N ILE 41.A O no hydrogen 3.065 N/A TYR 44.A OH GLU 53.A OE2 no hydrogen 2.622 N/A LYS 47.A NZ LEU 6.A O no hydrogen 3.408 N/A ILE 48.A N ASN 7.A OD1 no hydrogen 2.874 N/A LYS 49.A N GLU 53.A OE1 no hydrogen 2.912 N/A GLY 51.A N ASP 69.A OD1 no hydrogen 2.841 N/A GLU 53.A N SER 50.A OG no hydrogen 3.126 N/A ALA 54.A N SER 50.A O no hydrogen 3.330 N/A LYS 55.A N GLY 51.A O no hydrogen 2.853 N/A LYS 56.A N GLU 53.A O no hydrogen 3.332 N/A LEU 57.A N ALA 54.A O no hydrogen 2.878 N/A VAL 60.A N LEU 57.A O no hydrogen 3.259 N/A ALA 65.A N GLY 61.A O no hydrogen 3.055 N/A GLU 66.A N THR 62.A O no hydrogen 3.123 N/A LYS 67.A N LYS 63.A O no hydrogen 3.044 N/A ILE 68.A N ILE 64.A O no hydrogen 2.857 N/A ASP 69.A N ALA 65.A O no hydrogen 3.017 N/A GLU 70.A N GLU 66.A O no hydrogen 3.109 N/A PHE 71.A N LYS 67.A O no hydrogen 2.920 N/A LEU 72.A N ILE 68.A O no hydrogen 2.884 N/A ALA 73.A N ASP 69.A O no hydrogen 3.066 N/A THR 74.A N GLU 70.A O no hydrogen 2.841 N/A THR 74.A OG1 GLU 70.A O no hydrogen 2.753 N/A GLY 75.A N PHE 71.A O no hydrogen 2.712 N/A LYS 76.A N THR 74.A OG1 no hydrogen 3.316 N/A ARG 78.A N GLU 70.A OE2 no hydrogen 2.729 N/A GLU 81.A N LEU 77.A O no hydrogen 2.849 N/A LYS 82.A N ARG 78.A O no hydrogen 2.903 N/A LYS 82.A NZ GLN 85.A OE1 no hydrogen 3.551 N/A ILE 83.A N LYS 79.A O no hydrogen 3.030 N/A ARG 84.A N LEU 80.A O no hydrogen 2.912 N/A ARG 84.A NE GLU 16.A OE1 no hydrogen 3.271 N/A ARG 84.A NE GLU 16.A OE2 no hydrogen 2.750 N/A ARG 84.A NH2 GLU 16.A OE1 no hydrogen 2.710 N/A GLN 85.A N GLU 81.A O no hydrogen 3.336 N/A GLN 85.A NE2 GLU 81.A O no hydrogen 3.699 N/A ASP 86.A N ILE 83.A O no hydrogen 2.984 N/A SER 89.A N ASP 86.A OD1 no hydrogen 2.843 N/A SER 89.A OG ASP 86.A OD1 no hydrogen 3.229 N/A SER 90.A N ASP 86.A O no hydrogen 2.866 N/A SER 90.A OG ILE 83.A O no hydrogen 3.412 N/A SER 90.A OG ARG 84.A O no hydrogen 2.695 N/A SER 90.A OG ASP 86.A O no hydrogen 3.070 N/A SER 91.A N ASP 87.A O no hydrogen 3.022 N/A SER 91.A OG ASP 87.A O no hydrogen 2.683 N/A ILE 92.A N THR 88.A O no hydrogen 2.990 N/A ASN 93.A N SER 89.A O no hydrogen 2.922 N/A PHE 94.A N SER 90.A O no hydrogen 2.973 N/A LEU 95.A N SER 91.A O no hydrogen 2.999 N/A THR 96.A N ILE 92.A O no hydrogen 3.427 N/A THR 96.A OG1 ASN 93.A O no hydrogen 2.808 N/A ARG 97.A N PHE 94.A O no hydrogen 2.891 N/A ARG 97.A NE GLU 142.A OE2 no hydrogen 2.808 N/A ARG 97.A NH2 GLU 142.A OE1 no hydrogen 2.749 N/A ARG 97.A NH2 GLU 142.A OE2 no hydrogen 3.403 N/A VAL 98.A N LEU 95.A O no hydrogen 3.001 N/A SER 99.A OG HIS 130.A NE2 no hydrogen 2.838 N/A ILE 101.A N VAL 98.A O no hydrogen 2.956 N/A ALA 106.A N GLY 102.A O no hydrogen 2.983 N/A ARG 107.A N PRO 103.A O no hydrogen 3.182 N/A ARG 107.A NE GLN 26.A OE1 no hydrogen 3.434 N/A ARG 107.A NH2 VAL 24.A O no hydrogen 2.663 N/A LYS 108.A N SER 104.A O no hydrogen 3.123 N/A PHE 109.A N ALA 105.A O no hydrogen 2.929 N/A VAL 110.A N ALA 106.A O no hydrogen 3.035 N/A ASP 111.A N ARG 107.A O no hydrogen 2.892 N/A GLU 112.A N LYS 108.A O no hydrogen 3.250 N/A GLU 112.A N PHE 109.A O no hydrogen 2.928 N/A GLY 113.A N VAL 110.A O no hydrogen 2.936 N/A ILE 114.A N PHE 109.A O no hydrogen 2.846 N/A LYS 115.A N ASP 119.A OD2 no hydrogen 2.943 N/A LYS 115.A NZ ASP 87.A OD2 no hydrogen 2.794 N/A THR 116.A N ASP 119.A OD2 no hydrogen 3.303 N/A THR 116.A OG1 GLU 118.A OE1 no hydrogen 3.533 N/A GLU 118.A N GLU 118.A OE1 no hydrogen 2.704 N/A ASP 119.A N THR 116.A OG1 no hydrogen 3.116 N/A LEU 120.A N THR 116.A O no hydrogen 3.097 N/A ARG 121.A N LEU 117.A O no hydrogen 2.808 N/A LYS 122.A N GLU 118.A O no hydrogen 3.160 N/A ASN 123.A N LEU 120.A O no hydrogen 2.907 N/A ASN 123.A ND2 ASP 119.A O no hydrogen 2.804 N/A LYS 126.A N ASN 123.A O no hydrogen 2.848 N/A LEU 127.A N GLU 124.A O no hydrogen 2.929 N/A ASN 128.A N GLN 131.A OE1 no hydrogen 2.992 N/A HIS 129.A NE2 THR 219.A O no hydrogen 2.797 N/A HIS 130.A NE2 SER 99.A OG no hydrogen 2.838 N/A GLN 131.A N ASN 128.A OD1 no hydrogen 2.884 N/A GLN 131.A NE2 GLY 100.A O no hydrogen 2.990 N/A ARG 132.A N ASN 128.A O no hydrogen 2.952 N/A ARG 132.A NE GLU 124.A O no hydrogen 3.382 N/A ARG 132.A NH2 GLU 124.A O no hydrogen 3.235 N/A ILE 133.A N HIS 129.A O no hydrogen 3.133 N/A GLY 134.A N HIS 130.A O no hydrogen 2.817 N/A LEU 135.A N GLN 131.A O no hydrogen 2.892 N/A LYS 136.A N ARG 132.A O no hydrogen 2.889 N/A LYS 136.A NZ TYR 137.A OH no hydrogen 3.284 N/A TYR 137.A N ILE 133.A O no hydrogen 3.016 N/A TYR 137.A OH ASP 218.A OD1 no hydrogen 2.792 N/A PHE 138.A N LEU 135.A O no hydrogen 3.088 N/A PHE 141.A N TYR 137.A O no hydrogen 2.905 N/A GLU 142.A N GLY 139.A O no hydrogen 3.148 N/A LYS 143.A N ASP 140.A O no hydrogen 2.894 N/A ARG 144.A NE SER 182.A OG no hydrogen 3.323 N/A ILE 145.A N SER 183.A O no hydrogen 2.609 N/A ARG 147.A N GLU 181.A O no hydrogen 3.021 N/A ARG 147.A NH1 PHE 176.A O no hydrogen 3.039 N/A ARG 147.A NH1 ALA 180.A O no hydrogen 3.025 N/A ARG 147.A NH2 PHE 176.A O no hydrogen 3.420 N/A MET 150.A N PRO 146.A O no hydrogen 3.048 N/A LEU 151.A N ARG 147.A O no hydrogen 2.888 N/A GLN 152.A N GLU 148.A O no hydrogen 3.237 N/A MET 153.A N GLU 149.A O no hydrogen 2.843 N/A GLN 154.A N MET 150.A O no hydrogen 2.714 N/A ASP 155.A N LEU 151.A O no hydrogen 2.837 N/A ILE 156.A N GLN 152.A O no hydrogen 3.213 N/A VAL 157.A N MET 153.A O no hydrogen 3.020 N/A LEU 158.A N GLN 154.A O no hydrogen 2.898 N/A ASN 159.A N ASP 155.A O no hydrogen 3.053 N/A GLU 160.A N ILE 156.A O no hydrogen 2.930 N/A VAL 161.A N VAL 157.A O no hydrogen 2.959 N/A LYS 162.A N LEU 158.A O no hydrogen 3.201 N/A LYS 163.A N ASN 159.A O no hydrogen 3.003 N/A LYS 163.A NZ GLU 160.A OE2 no hydrogen 3.499 N/A VAL 164.A N GLU 160.A O no hydrogen 3.142 N/A ASP 165.A N VAL 161.A O no hydrogen 3.175 N/A GLU 167.A N ASP 165.A OD1 no hydrogen 3.009 N/A TYR 168.A N ASP 165.A O no hydrogen 3.059 N/A TYR 168.A OH LEU 202.A O no hydrogen 2.644 N/A ILE 169.A N THR 191.A O no hydrogen 2.833 N/A THR 171.A N LEU 189.A O no hydrogen 2.833 N/A THR 171.A OG1 TYR 257.A OH no hydrogen 2.530 N/A CYS 173.A N ASP 187.A O no hydrogen 2.831 N/A CYS 173.A SG THR 171.A O no hydrogen 3.693 N/A GLY 174.A N PHE 264.A O no hydrogen 2.957 N/A SER 175.A OG SER 183.A OG no hydrogen 3.027 N/A ARG 177.A N CYS 173.A O no hydrogen 3.359 N/A ARG 177.A N GLY 174.A O no hydrogen 3.058 N/A ARG 177.A NH1 THR 265.A OG1 no hydrogen 2.965 N/A ARG 177.A NH1 GLU 306.A OE2 no hydrogen 3.302 N/A ARG 177.A NH2 GLU 306.A OE1 no hydrogen 3.138 N/A ARG 178.A NH1 THR 265.A O no hydrogen 2.693 N/A GLY 179.A N PHE 176.A O no hydrogen 2.915 N/A ALA 180.A N SER 175.A O no hydrogen 3.061 N/A SER 183.A N ILE 145.A O no hydrogen 2.899 N/A SER 183.A OG SER 175.A OG no hydrogen 3.027 N/A MET 186.A N ARG 246.A O no hydrogen 3.003 N/A VAL 188.A N ASP 248.A O no hydrogen 2.909 N/A LEU 189.A N THR 171.A O no hydrogen 2.799 N/A LEU 190.A N ARG 250.A O no hydrogen 2.856 N/A THR 191.A N ILE 169.A O no hydrogen 2.794 N/A THR 191.A OG1 ILE 252.A O no hydrogen 2.933 N/A HIS 192.A ND1 SER 194.A OG no hydrogen 2.943 N/A HIS 192.A NE2 ASP 165.A OD2 no hydrogen 2.878 N/A SER 194.A N HIS 192.A ND1 no hydrogen 3.310 N/A SER 194.A OG HIS 192.A ND1 no hydrogen 2.943 N/A PHE 195.A N HIS 192.A O no hydrogen 2.889 N/A THR 196.A N SER 199.A OG no hydrogen 2.764 N/A THR 196.A OG1 GLU 198.A O no hydrogen 3.421 N/A SER 197.A N ASP 255.A OD1 no hydrogen 2.930 N/A SER 197.A OG ASP 255.A OD1 no hydrogen 3.131 N/A SER 197.A OG ASP 255.A OD2 no hydrogen 2.541 N/A SER 199.A OG SER 194.A O no hydrogen 3.297 N/A SER 199.A OG THR 196.A O no hydrogen 2.795 N/A GLN 205.A N LYS 201.A O no hydrogen 3.023 N/A GLN 205.A NE2.A TYR 168.A OH no hydrogen 2.856 N/A VAL 207.A N LEU 203.A O no hydrogen 3.100 N/A GLU 208.A N HIS 204.A O no hydrogen 2.768 N/A GLN 209.A N GLN 205.A O no hydrogen 3.027 N/A GLN 209.A NE2 GLU 160.A OE1 no hydrogen 2.783 N/A LEU 210.A N VAL 206.A O no hydrogen 2.989 N/A GLN 211.A N VAL 207.A O no hydrogen 2.946 N/A LYS 212.A N GLU 208.A O no hydrogen 2.863 N/A VAL 213.A N GLN 209.A O no hydrogen 3.120 N/A HIS 214.A N GLN 211.A O no hydrogen 2.967 N/A PHE 215.A N LEU 210.A O no hydrogen 3.040 N/A ILE 216.A N LEU 210.A O no hydrogen 3.100 N/A THR 217.A N VAL 230.A O no hydrogen 2.799 N/A THR 217.A OG1 ASP 218.A OD1 no hydrogen 2.772 N/A THR 217.A OG1 VAL 230.A O no hydrogen 3.316 N/A LEU 220.A N MET 228.A O no hydrogen 2.694 N/A SER 221.A N MET 228.A O no hydrogen 3.075 N/A LYS 222.A NZ HIS 204.A ND1 no hydrogen 3.234 N/A GLY 223.A N LYS 226.A O no hydrogen 3.032 N/A PHE 227.A N ILE 249.A O no hydrogen 2.795 N/A MET 228.A N SER 221.A O no hydrogen 2.883 N/A GLY 229.A N ILE 247.A O no hydrogen 2.936 N/A VAL 230.A N ASP 218.A O no hydrogen 2.970 N/A CYS 231.A N ARG 245.A O no hydrogen 2.828 N/A CYS 231.A SG ARG 245.A O no hydrogen 3.826 N/A GLN 232.A N PHE 215.A O no hydrogen 2.896 N/A GLN 232.A NE2 GLU 241.A OE1 no hydrogen 3.247 N/A GLN 232.A NE2 TYR 242.A O no hydrogen 2.908 N/A GLU 239.A N LYS 236.A O no hydrogen 2.906 N/A HIS 244.A N ASP 140.A OD2 no hydrogen 2.850 N/A ARG 245.A N CYS 231.A O no hydrogen 2.841 N/A ARG 245.A NH2 GLU 149.A OE1 no hydrogen 2.732 N/A ARG 246.A NH1 GLY 229.A O no hydrogen 3.015 N/A ARG 246.A NH1 ILE 247.A O no hydrogen 3.144 N/A ARG 246.A NH1 ASP 248.A OD1 no hydrogen 2.859 N/A ARG 246.A NH2 ASP 248.A OD1 no hydrogen 2.893 N/A ILE 247.A N GLY 229.A O no hydrogen 3.050 N/A ASP 248.A N MET 186.A O no hydrogen 2.876 N/A ILE 249.A N PHE 227.A O no hydrogen 2.869 N/A ARG 250.A N VAL 188.A O no hydrogen 2.959 N/A ARG 250.A NH2 ASP 248.A OD2 no hydrogen 3.421 N/A LEU 251.A N THR 225.A O no hydrogen 2.763 N/A ILE 252.A N LEU 190.A O no hydrogen 2.916 N/A LYS 254.A N PHE 195.A O no hydrogen 2.753 N/A GLN 256.A N PRO 253.A O no hydrogen 2.987 N/A TYR 257.A N LYS 254.A O no hydrogen 3.223 N/A TYR 257.A OH THR 171.A OG1 no hydrogen 2.530 N/A TYR 257.A OH LEU 189.A O no hydrogen 3.282 N/A GLY 260.A N GLN 256.A O no hydrogen 3.123 N/A VAL 261.A N TYR 257.A O no hydrogen 2.859 N/A LEU 262.A N TYR 258.A O no hydrogen 3.096 N/A TYR 263.A N CYS 259.A O no hydrogen 3.020 N/A PHE 264.A N GLY 260.A O no hydrogen 2.865 N/A THR 265.A N VAL 261.A O no hydrogen 2.894 N/A THR 265.A OG1 VAL 261.A O no hydrogen 2.473 N/A GLY 266.A N LEU 262.A O no hydrogen 3.323 N/A SER 267.A N ARG 323.A O no hydrogen 3.102 N/A SER 267.A OG ARG 323.A O no hydrogen 2.679 N/A PHE 270.A N SER 267.A OG no hydrogen 3.051 N/A ASN 271.A N SER 267.A O no hydrogen 2.993 N/A ASN 271.A ND2 TYR 263.A O no hydrogen 2.825 N/A LYS 272.A N ASP 268.A O no hydrogen 3.079 N/A ASN 273.A N ILE 269.A O no hydrogen 3.206 N/A MET 274.A N PHE 270.A O no hydrogen 2.766 N/A ARG 275.A N ASN 271.A O no hydrogen 2.707 N/A ALA 276.A N LYS 272.A O no hydrogen 2.727 N/A HIS 277.A N ASN 273.A O no hydrogen 2.839 N/A THR 282.A N ARG 289.A O no hydrogen 2.842 N/A ASN 284.A N THR 287.A O no hydrogen 3.018 N/A TYR 286.A N ASN 284.A OD1 no hydrogen 2.888 N/A THR 287.A N ASN 284.A OD1 no hydrogen 2.671 N/A THR 287.A OG1 ASN 284.A OD1 no hydrogen 2.949 N/A ARG 289.A N THR 282.A O no hydrogen 2.871 N/A ARG 289.A NH1 GLY 298.A O no hydrogen 3.035 N/A LEU 291.A N GLY 280.A O no hydrogen 2.895 N/A GLY 292.A N VAL 296.A O no hydrogen 2.685 N/A GLY 295.A N GLY 292.A O no hydrogen 3.150 N/A GLY 298.A N PRO 290.A O no hydrogen 2.948 N/A LEU 301.A N ILE 288.A O no hydrogen 3.033 N/A ASP 304.A N ASP 308.A OD2 no hydrogen 2.858 N/A ASP 308.A N SER 305.A O no hydrogen 3.225 N/A ASP 308.A N SER 305.A OG no hydrogen 3.133 N/A ILE 309.A N GLU 306.A O no hydrogen 3.058 N/A ASP 311.A N LYS 307.A O no hydrogen 2.757 N/A TYR 312.A N ASP 308.A O no hydrogen 2.917 N/A TYR 312.A OH PRO 302.A O no hydrogen 2.709 N/A GLN 314.A N ASP 311.A O no hydrogen 2.718 N/A TRP 315.A N PHE 310.A O no hydrogen 2.846 N/A ARG 318.A NE LYS 316.A O no hydrogen 2.758 N/A ASP 322.A N GLU 319.A O no hydrogen 2.675 N/A ARG 323.A N PRO 320.A O no hydrogen 3.194 N/A ARG 323.A NE ARG 318.A O no hydrogen 3.238 N/A ARG 323.A NH1 GLU 306.A OE2 no hydrogen 2.775 N/A ARG 323.A NH2 GLU 306.A OE1 no hydrogen 3.185 N/A ARG 323.A NH2 ARG 318.A O no hydrogen 2.887 N/A