Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5v0n_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N PHE 1.A O no hydrogen 2.895 N/A VAL 5.A N VAL 2.A O no hydrogen 3.205 N/A ASP 6.A N SER 166.A OG no hydrogen 2.881 N/A ASN 7.A N MET 4.A O no hydrogen 3.235 N/A ASN 7.A ND2 HIS 91.A O no hydrogen 3.025 N/A ASN 7.A ND2 MET 167.A O no hydrogen 2.943 N/A LEU 8.A N GLY 165.A O no hydrogen 2.939 N/A ARG 9.A N TYR 17.A O no hydrogen 3.101 N/A GLY 10.A N VAL 163.A O no hydrogen 3.090 N/A SER 12.A OG PRO 301.A O no hydrogen 3.548 N/A GLN 14.A N LYS 11.A O no hydrogen 2.877 N/A TYR 16.A OH CYS 157.A O no hydrogen 2.897 N/A TYR 16.A OH GLU 325.A OE2 no hydrogen 3.010 N/A TYR 17.A N ARG 9.A O no hydrogen 2.791 N/A VAL 18.A N ILE 31.A O no hydrogen 2.895 N/A MET 20.A N LEU 29.A O no hydrogen 2.885 N/A THR 21.A N SER 88.A O no hydrogen 2.867 N/A VAL 22.A N GLN 27.A O no hydrogen 2.846 N/A GLY 23.A N LEU 86.A O no hydrogen 2.861 N/A SER 24.A N SER 59.A OG no hydrogen 3.042 N/A SER 24.A OG THR 61.A OG1 no hydrogen 2.635 N/A GLN 27.A N VAL 22.A O no hydrogen 2.740 N/A GLN 27.A NE2 GLN 55.A O no hydrogen 3.066 N/A LEU 29.A N MET 20.A O no hydrogen 2.929 N/A ASN 30.A N GLU 118.A OE2 no hydrogen 2.969 N/A ASN 30.A ND2 ASN 116.A O no hydrogen 2.849 N/A ILE 31.A N VAL 18.A O no hydrogen 2.893 N/A LEU 32.A N GLY 119.A O no hydrogen 2.889 N/A VAL 33.A N TYR 16.A O no hydrogen 2.829 N/A ASP 34.A N LEU 121.A O no hydrogen 3.020 N/A THR 35.A N SER 222.A OG no hydrogen 2.999 N/A THR 35.A OG1 VAL 220.A O no hydrogen 2.828 N/A GLY 36.A N ASP 34.A OD1 no hydrogen 2.850 N/A SER 37.A OG ASP 34.A OD2 no hydrogen 2.597 N/A SER 38.A OG TYR 125.A O no hydrogen 2.622 N/A ASN 39.A ND2 ARG 130.A O no hydrogen 2.819 N/A ALA 41.A N ILE 120.A O no hydrogen 3.031 N/A VAL 42.A N ALA 102.A O no hydrogen 2.959 N/A GLY 43.A N GLU 118.A O no hydrogen 2.882 N/A ALA 44.A N ILE 104.A O no hydrogen 2.919 N/A PHE 49.A N HIS 47.A ND1 no hydrogen 2.978 N/A LEU 50.A N HIS 47.A O no hydrogen 2.996 N/A ARG 52.A NE GLU 118.A OE2 no hydrogen 3.053 N/A TYR 54.A N GLY 43.A O no hydrogen 2.675 N/A TYR 54.A OH ASP 85.A OD2 no hydrogen 2.528 N/A GLN 55.A N GLN 27.A OE1 no hydrogen 2.794 N/A LEU 58.A N GLN 55.A O no hydrogen 3.060 N/A SER 59.A N ARG 56.A O no hydrogen 3.306 N/A SER 59.A OG ASP 85.A OD1 no hydrogen 3.342 N/A SER 59.A OG ASP 85.A OD2 no hydrogen 2.953 N/A SER 60.A N SER 24.A O no hydrogen 2.948 N/A SER 60.A OG SER 24.A O no hydrogen 3.325 N/A THR 61.A N SER 59.A OG no hydrogen 3.302 N/A THR 61.A OG1 SER 24.A OG no hydrogen 2.635 N/A THR 61.A OG1 SER 59.A OG no hydrogen 3.034 N/A THR 61.A OG1 ASP 85.A OD1 no hydrogen 2.634 N/A TYR 62.A N SER 59.A O no hydrogen 3.299 N/A ARG 63.A N THR 84.A O no hydrogen 3.058 N/A LEU 65.A N LEU 82.A O no hydrogen 3.068 N/A ARG 66.A N ASP 64.A OD1 no hydrogen 2.726 N/A LYS 67.A N GLU 81.A OE2 no hydrogen 3.092 N/A VAL 69.A N GLY 80.A O no hydrogen 2.854 N/A VAL 71.A N TRP 78.A O no hydrogen 3.018 N/A TYR 73.A N GLY 76.A O no hydrogen 2.834 N/A LYS 77.A N ASP 108.A O no hydrogen 3.125 N/A LYS 77.A NZ ASP 108.A OD2 no hydrogen 3.268 N/A TRP 78.A N VAL 71.A O no hydrogen 3.217 N/A TRP 78.A NE1 TYR 73.A OH no hydrogen 2.829 N/A GLU 79.A N GLU 106.A O no hydrogen 2.958 N/A GLY 80.A N VAL 69.A O no hydrogen 2.765 N/A GLU 81.A N ALA 103.A O no hydrogen 2.996 N/A LEU 82.A N LYS 67.A O no hydrogen 2.716 N/A GLY 83.A N ILE 101.A O no hydrogen 2.993 N/A THR 84.A N ARG 63.A O no hydrogen 2.970 N/A ASP 85.A N ALA 99.A O no hydrogen 3.238 N/A LEU 86.A N ASP 85.A OD1 no hydrogen 2.750 N/A VAL 87.A N VAL 97.A O no hydrogen 2.783 N/A SER 88.A N THR 21.A O no hydrogen 2.984 N/A SER 88.A OG VAL 95.A O no hydrogen 3.562 N/A SER 88.A OG THR 96.A OG1 no hydrogen 3.103 N/A VAL 95.A N PRO 93.A O no hydrogen 2.829 N/A THR 96.A OG1 SER 88.A OG no hydrogen 3.103 N/A VAL 97.A N VAL 87.A O no hydrogen 3.069 N/A ARG 98.A N GLN 145.A OE1 no hydrogen 2.957 N/A ARG 98.A NH1 THR 61.A O no hydrogen 2.938 N/A ARG 98.A NH1 THR 84.A OG1 no hydrogen 2.859 N/A ARG 98.A NH2 THR 61.A O no hydrogen 2.857 N/A ALA 99.A N ASP 85.A O no hydrogen 2.944 N/A ASN 100.A ND2 GLU 136.A O no hydrogen 2.999 N/A ILE 101.A N GLY 83.A O no hydrogen 2.788 N/A ALA 102.A N PHE 40.A O no hydrogen 2.906 N/A ALA 103.A N GLU 81.A O no hydrogen 2.962 N/A ILE 104.A N VAL 42.A O no hydrogen 2.743 N/A THR 105.A N GLU 79.A O no hydrogen 3.122 N/A THR 105.A OG1 GLU 79.A O no hydrogen 3.535 N/A GLU 106.A N GLU 79.A O no hydrogen 3.272 N/A ASP 108.A N LYS 77.A O no hydrogen 2.988 N/A SER 115.A N ILE 112.A O no hydrogen 3.169 N/A SER 115.A OG ILE 112.A O no hydrogen 3.416 N/A ASN 116.A ND2 TYR 17.A OH no hydrogen 2.865 N/A TRP 117.A N SER 115.A OG no hydrogen 3.219 N/A TRP 117.A NE1 GLN 14.A O no hydrogen 2.795 N/A GLU 118.A N ASN 30.A O no hydrogen 2.727 N/A ILE 120.A N ALA 41.A O no hydrogen 2.828 N/A LEU 121.A N LEU 32.A O no hydrogen 2.676 N/A GLY 122.A N ASN 39.A O no hydrogen 2.907 N/A LEU 123.A N ASP 34.A O no hydrogen 2.673 N/A ALA 124.A N SER 37.A O no hydrogen 2.860 N/A TYR 125.A N TRP 190.A O no hydrogen 3.031 N/A ILE 128.A N TYR 125.A O no hydrogen 3.244 N/A ALA 129.A N ALA 126.A O no hydrogen 2.940 N/A ARG 130.A N ASN 39.A OD1 no hydrogen 2.847 N/A SER 134.A N ASP 132.A OD1 no hydrogen 3.182 N/A SER 134.A OG ASP 132.A OD1 no hydrogen 2.242 N/A LEU 135.A N ASP 132.A O no hydrogen 3.177 N/A SER 141.A N PRO 137.A O no hydrogen 3.128 N/A SER 141.A OG GLU 136.A OE1 no hydrogen 2.587 N/A SER 141.A OG PRO 137.A O no hydrogen 3.400 N/A LEU 142.A N PHE 138.A O no hydrogen 2.870 N/A VAL 143.A N PHE 139.A O no hydrogen 3.001 N/A LYS 144.A N ASP 140.A O no hydrogen 3.038 N/A GLN 145.A N SER 141.A O no hydrogen 2.952 N/A GLN 145.A NE2 ARG 98.A O no hydrogen 3.036 N/A THR 146.A N LEU 142.A O no hydrogen 3.023 N/A THR 146.A OG1 LEU 142.A O no hydrogen 2.777 N/A VAL 148.A N THR 146.A OG1 no hydrogen 2.946 N/A LEU 151.A N PRO 149.A O no hydrogen 2.861 N/A PHE 152.A N PHE 331.A O no hydrogen 3.232 N/A SER 153.A N ILE 168.A O no hydrogen 2.918 N/A SER 153.A OG GLY 171.A O no hydrogen 2.698 N/A SER 153.A OG TYR 328.A OH no hydrogen 2.646 N/A LEU 154.A N VAL 329.A O no hydrogen 2.776 N/A GLN 155.A N SER 166.A O no hydrogen 2.773 N/A GLN 155.A NE2 SER 343.A OG no hydrogen 3.281 N/A CYS 157.A N GLY 164.A O no hydrogen 2.977 N/A SER 162.A OG GLY 10.A O no hydrogen 3.272 N/A VAL 163.A N GLY 10.A O no hydrogen 3.034 N/A GLY 165.A N LEU 8.A O no hydrogen 3.154 N/A SER 166.A N GLN 155.A O no hydrogen 2.730 N/A SER 166.A OG GLN 155.A OE1 no hydrogen 2.902 N/A MET 167.A N ASN 7.A OD1 no hydrogen 2.781 N/A ILE 168.A N SER 153.A O no hydrogen 2.944 N/A GLY 170.A N LEU 151.A O no hydrogen 2.776 N/A ASP 173.A N TYR 328.A OH no hydrogen 2.953 N/A SER 175.A N ASP 173.A OD1 no hydrogen 2.982 N/A SER 175.A OG ASP 173.A OD1 no hydrogen 2.728 N/A LEU 176.A N ASP 173.A O no hydrogen 2.988 N/A TYR 177.A OH HIS 174.A ND1 no hydrogen 2.837 N/A THR 178.A N VAL 342.A O no hydrogen 3.018 N/A SER 180.A OG LEU 181.A O no hydrogen 3.109 N/A TRP 182.A N PHE 340.A O no hydrogen 2.858 N/A THR 184.A N ILE 338.A O no hydrogen 2.791 N/A THR 184.A OG1 MET 281.A O no hydrogen 2.621 N/A ILE 186.A N LYS 336.A O no hydrogen 2.862 N/A ARG 187.A N GLU 193.A O no hydrogen 2.722 N/A ARG 187.A NH1 GLU 193.A OE2 no hydrogen 3.092 N/A ARG 187.A NH1 TYR 370.A O no hydrogen 3.001 N/A ARG 187.A NH2 TYR 370.A O no hydrogen 3.048 N/A ARG 188.A NE GLU 127.A OE2 no hydrogen 2.894 N/A ARG 188.A NH2 GLU 127.A OE2 no hydrogen 2.665 N/A TRP 190.A N ARG 188.A O no hydrogen 3.085 N/A TRP 190.A N TYR 191.A O no hydrogen 3.110 N/A TRP 190.A NE1 GLU 193.A OE1 no hydrogen 2.879 N/A TYR 192.A OH LEU 123.A O no hydrogen 2.708 N/A VAL 194.A N SER 218.A O no hydrogen 2.871 N/A ILE 196.A N ASN 214.A OD1 no hydrogen 2.903 N/A VAL 197.A N TYR 279.A O no hydrogen 2.727 N/A ARG 198.A NH2 VAL 361.A O no hydrogen 3.533 N/A GLU 200.A N SER 277.A O no hydrogen 3.087 N/A ILE 201.A N GLN 204.A O no hydrogen 2.795 N/A ASN 202.A N VAL 275.A O no hydrogen 2.795 N/A GLN 204.A N ILE 201.A O no hydrogen 2.901 N/A LEU 206.A N VAL 199.A O no hydrogen 2.895 N/A LYS 207.A N ASP 205.A OD1 no hydrogen 2.715 N/A LYS 211.A N ASP 209.A OD1 no hydrogen 3.074 N/A LYS 211.A NZ ASP 367.A O no hydrogen 2.849 N/A GLU 212.A N ASP 209.A O no hydrogen 2.876 N/A TYR 213.A N CYS 210.A O no hydrogen 3.107 N/A ASN 214.A N LYS 211.A O no hydrogen 3.097 N/A ASN 214.A ND2 ILE 196.A O no hydrogen 2.883 N/A ASN 214.A ND2 CYS 368.A O no hydrogen 3.060 N/A TYR 215.A N GLU 212.A O no hydrogen 3.181 N/A LYS 217.A NZ ASP 216.A OD2 no hydrogen 2.335 N/A LYS 217.A NZ THR 315.A O no hydrogen 2.865 N/A SER 218.A OG ASN 214.A OD1 no hydrogen 2.535 N/A ILE 219.A N THR 317.A O no hydrogen 2.987 N/A VAL 220.A N TYR 192.A O no hydrogen 3.017 N/A ASP 221.A N MET 319.A O no hydrogen 2.930 N/A SER 222.A N THR 35.A OG1 no hydrogen 2.981 N/A SER 222.A OG VAL 33.A O no hydrogen 2.761 N/A GLY 223.A N ASP 221.A OD1 no hydrogen 2.989 N/A THR 224.A N ASP 221.A O no hydrogen 3.358 N/A THR 224.A OG1 ASP 221.A OD2 no hydrogen 2.621 N/A THR 225.A OG1 GLY 13.A O no hydrogen 3.355 N/A ASN 226.A ND2 SER 311.A OG no hydrogen 2.846 N/A LEU 227.A N ALA 309.A O no hydrogen 2.972 N/A ARG 228.A N VAL 318.A O no hydrogen 2.868 N/A ARG 228.A NH1 GLN 312.A O no hydrogen 2.884 N/A LEU 229.A N SER 311.A O no hydrogen 2.867 N/A LYS 231.A NZ GLU 235.A OE2 no hydrogen 3.493 N/A LYS 232.A NZ GLU 212.A OE2 no hydrogen 3.449 N/A PHE 234.A N PRO 230.A O no hydrogen 2.769 N/A GLU 235.A N LYS 231.A O no hydrogen 2.966 N/A ALA 236.A N LYS 232.A O no hydrogen 3.101 N/A ALA 237.A N VAL 233.A O no hydrogen 2.831 N/A VAL 238.A N PHE 234.A O no hydrogen 2.910 N/A LYS 239.A N GLU 235.A O no hydrogen 3.075 N/A SER 240.A N ALA 236.A O no hydrogen 3.149 N/A ILE 241.A N ALA 237.A O no hydrogen 2.839 N/A LYS 242.A N VAL 238.A O no hydrogen 2.726 N/A ALA 243.A N LYS 239.A O no hydrogen 3.042 N/A ALA 244.A N SER 240.A O no hydrogen 3.076 N/A SER 245.A N ILE 241.A O no hydrogen 3.183 N/A SER 245.A N LYS 242.A O no hydrogen 2.995 N/A SER 245.A OG ILE 241.A O no hydrogen 2.767 N/A SER 245.A OG LYS 242.A O no hydrogen 3.242 N/A SER 246.A OG ALA 243.A O no hydrogen 3.113 N/A GLU 248.A N SER 245.A O no hydrogen 3.007 N/A PHE 254.A N PRO 251.A O no hydrogen 2.558 N/A GLY 257.A N PHE 254.A O no hydrogen 3.122 N/A GLU 258.A N GLY 253.A O no hydrogen 2.888 N/A GLN 259.A N GLY 253.A O no hydrogen 3.173 N/A VAL 261.A N TYR 306.A O no hydrogen 3.044 N/A TRP 263.A N ASP 304.A O no hydrogen 2.821 N/A TRP 263.A NE1 GLU 248.A OE1 no hydrogen 2.944 N/A GLY 266.A N ASP 304.A OD2 no hydrogen 2.878 N/A THR 267.A N GLN 264.A O no hydrogen 2.870 N/A THR 267.A OG1 GLN 264.A O no hydrogen 2.612 N/A THR 268.A OG1 TYR 306.A OH no hydrogen 2.648 N/A TRP 270.A N THR 268.A O no hydrogen 2.965 N/A ILE 272.A N PRO 269.A O no hydrogen 3.279 N/A PHE 273.A N TRP 270.A O no hydrogen 3.076 N/A VAL 275.A N ASN 202.A OD1 no hydrogen 3.053 N/A ILE 276.A N ILE 293.A O no hydrogen 3.042 N/A SER 277.A N GLU 200.A O no hydrogen 2.847 N/A SER 277.A OG THR 292.A OG1 no hydrogen 2.866 N/A LEU 278.A N ILE 291.A O no hydrogen 2.910 N/A TYR 279.A N ARG 198.A O no hydrogen 2.945 N/A TYR 279.A OH GLU 200.A OE1 no hydrogen 2.744 N/A LEU 280.A N PHE 289.A O no hydrogen 2.911 N/A MET 281.A N ILE 195.A O no hydrogen 3.137 N/A GLY 282.A N GLN 287.A O no hydrogen 2.758 N/A GLU 283.A N GLN 287.A OE1 no hydrogen 2.896 N/A VAL 284.A N GLN 287.A OE1 no hydrogen 3.019 N/A GLN 287.A N VAL 284.A O no hydrogen 3.241 N/A GLN 287.A NE2 SER 288.A O no hydrogen 3.235 N/A SER 288.A N PHE 360.A O no hydrogen 2.818 N/A SER 288.A OG THR 362.A OG1 no hydrogen 2.721 N/A PHE 289.A N LEU 280.A O no hydrogen 3.218 N/A ARG 290.A N GLU 357.A O no hydrogen 2.845 N/A ARG 290.A NE GLU 357.A OE1 no hydrogen 2.839 N/A ARG 290.A NH1 TYR 279.A OH no hydrogen 2.925 N/A ARG 290.A NH2 GLU 357.A OE1 no hydrogen 2.671 N/A ILE 291.A N LEU 278.A O no hydrogen 2.938 N/A THR 292.A N ALA 355.A O no hydrogen 2.822 N/A THR 292.A OG1 SER 277.A OG no hydrogen 2.866 N/A ILE 293.A N ILE 276.A O no hydrogen 2.736 N/A LEU 294.A N GLN 297.A OE1 no hydrogen 2.974 N/A GLN 296.A N GLN 296.A OE1 no hydrogen 2.792 N/A GLN 296.A NE2 ASP 349.A OD1 no hydrogen 2.894 N/A GLN 297.A N LEU 294.A O no hydrogen 2.867 N/A GLN 297.A NE2 VAL 322.A O no hydrogen 3.015 N/A TYR 298.A OH PRO 274.A O no hydrogen 2.633 N/A LEU 299.A N PRO 295.A O no hydrogen 2.810 N/A ARG 300.A N LYS 307.A O no hydrogen 2.834 N/A VAL 302.A N CYS 305.A O no hydrogen 2.865 N/A ASP 304.A N TRP 263.A O no hydrogen 2.559 N/A TYR 306.A N VAL 261.A O no hydrogen 2.907 N/A TYR 306.A OH THR 268.A OG1 no hydrogen 2.648 N/A LYS 307.A N ARG 300.A O no hydrogen 2.883 N/A ALA 309.A N TYR 298.A O no hydrogen 2.955 N/A SER 311.A N LEU 227.A O no hydrogen 2.935 N/A SER 313.A N LEU 229.A O no hydrogen 2.941 N/A SER 313.A OG GLY 316.A O no hydrogen 2.809 N/A THR 315.A N SER 313.A OG no hydrogen 2.952 N/A THR 317.A N LYS 217.A O no hydrogen 2.892 N/A THR 317.A OG1 TYR 213.A O no hydrogen 2.765 N/A VAL 318.A N ARG 228.A O no hydrogen 2.857 N/A MET 319.A N ILE 219.A O no hydrogen 2.836 N/A ALA 321.A N THR 224.A O no hydrogen 2.811 N/A VAL 322.A N THR 225.A O no hydrogen 3.005 N/A ILE 323.A N GLY 320.A O no hydrogen 2.954 N/A MET 324.A N GLY 320.A O no hydrogen 2.996 N/A GLU 325.A N ALA 321.A O no hydrogen 2.846 N/A GLY 326.A N LEU 156.A O no hydrogen 3.022 N/A PHE 327.A N MET 324.A O no hydrogen 2.937 N/A TYR 328.A N ALA 341.A O no hydrogen 2.719 N/A VAL 329.A N LEU 154.A O no hydrogen 2.879 N/A VAL 330.A N GLY 339.A O no hydrogen 2.764 N/A PHE 331.A N PHE 152.A O no hydrogen 2.776 N/A ASP 332.A N ARG 337.A O no hydrogen 2.887 N/A ARG 333.A NE ASN 150.A OD1 no hydrogen 2.902 N/A ARG 333.A NH1 TYR 192.A OH no hydrogen 2.850 N/A ARG 333.A NH2 ASP 140.A OD1 no hydrogen 3.489 N/A ALA 334.A N ASN 150.A O no hydrogen 3.004 N/A ARG 335.A N ASP 332.A O no hydrogen 3.187 N/A ARG 335.A N ASP 332.A OD1 no hydrogen 3.177 N/A LYS 336.A N ARG 333.A O no hydrogen 3.215 N/A LYS 336.A NZ GLU 189.A OE2 no hydrogen 3.477 N/A ARG 337.A N ASP 332.A O no hydrogen 3.142 N/A ARG 337.A NE ASP 332.A OD2 no hydrogen 2.861 N/A ARG 337.A NH1 GLU 283.A OE1 no hydrogen 2.810 N/A ARG 337.A NH2 ASP 332.A OD2 no hydrogen 3.439 N/A ILE 338.A N THR 184.A O no hydrogen 2.790 N/A GLY 339.A N VAL 330.A O no hydrogen 2.865 N/A PHE 340.A N TRP 182.A O no hydrogen 2.802 N/A ALA 341.A N TYR 328.A O no hydrogen 3.022 N/A SER 343.A N GLY 326.A O no hydrogen 2.695 N/A ALA 344.A N LEU 176.A O no hydrogen 2.822 N/A CYS 345.A N SER 343.A OG no hydrogen 3.051 N/A CYS 345.A SG LEU 156.A O no hydrogen 3.802 N/A CYS 345.A SG SER 343.A OG no hydrogen 3.267 N/A PHE 351.A N ASP 349.A OD2 no hydrogen 3.374 N/A ARG 352.A NE ASP 349.A OD2 no hydrogen 3.167 N/A ARG 352.A NH1 PHE 273.A O no hydrogen 2.873 N/A ARG 352.A NH2 TRP 270.A O no hydrogen 2.991 N/A ARG 352.A NH2 ASP 349.A OD1 no hydrogen 3.360 N/A GLU 357.A N ARG 290.A O no hydrogen 2.916 N/A PHE 360.A N SER 288.A O no hydrogen 2.744 N/A THR 362.A N ASN 286.A O no hydrogen 2.983 N/A THR 362.A OG1 SER 288.A OG no hydrogen 2.721 N/A ASP 367.A N ASP 364.A O no hydrogen 2.996 N/A CYS 368.A N MET 365.A O no hydrogen 2.843 N/A GLY 369.A N GLU 366.A O no hydrogen 3.288 N/A