Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5wev_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 7.A NH2 GLU 5.A OE2 no hydrogen 3.047 N/A ASP 8.A N ASP 6.A OD1 no hydrogen 3.103 N/A THR 10.A N ASP 8.A OD1 no hydrogen 3.281 N/A THR 10.A OG1 ASP 8.A OD1 no hydrogen 2.700 N/A GLN 11.A N ASP 8.A O no hydrogen 3.218 N/A GLN 11.A NE2 ASP 8.A OD2 no hydrogen 2.734 N/A PHE 12.A N VAL 81.A O no hydrogen 2.850 N/A GLU 13.A N TYR 33.A OH no hydrogen 2.789 N/A HIS 16.A N GLU 13.A O no hydrogen 2.972 N/A LEU 17.A N GLU 14.A O no hydrogen 3.207 N/A LYS 18.A N ARG 32.A O no hydrogen 2.788 N/A LYS 18.A NZ ARG 15.A O no hydrogen 3.087 N/A LEU 20.A N MET 30.A O no hydrogen 2.830 N/A GLN 21.A N MET 30.A O no hydrogen 3.147 N/A GLN 22.A NE2 GLY 24.A O no hydrogen 3.437 N/A LEU 23.A N VAL 28.A O no hydrogen 2.789 N/A SER 27.A N LYS 48.A O no hydrogen 3.124 N/A VAL 28.A N GLY 24.A O no hydrogen 3.001 N/A GLU 29.A N VAL 46.A O no hydrogen 2.831 N/A MET 30.A N GLN 21.A O no hydrogen 2.722 N/A CYS 31.A N VAL 44.A O no hydrogen 2.902 N/A CYS 31.A SG GLU 29.A OE1 no hydrogen 3.753 N/A ARG 32.A N LYS 18.A O no hydrogen 2.823 N/A ARG 32.A NH1 ASP 34.A OD2 no hydrogen 3.027 N/A ARG 32.A NH1 THR 40.A O no hydrogen 3.106 N/A TYR 33.A N GLU 42.A O no hydrogen 2.849 N/A ASP 34.A N HIS 16.A O no hydrogen 2.911 N/A GLN 37.A N ASP 34.A O no hydrogen 3.248 N/A ASP 38.A N ASP 34.A OD1 no hydrogen 3.293 N/A ASN 39.A N ASP 34.A OD2 no hydrogen 3.041 N/A THR 40.A N ASP 38.A OD1 no hydrogen 3.328 N/A THR 40.A OG1 ASP 38.A OD1 no hydrogen 2.680 N/A THR 40.A OG1 ASP 38.A OD2 no hydrogen 3.429 N/A VAL 44.A N CYS 31.A O no hydrogen 2.815 N/A ALA 45.A N MET 94.A O no hydrogen 2.825 N/A VAL 46.A N GLU 29.A O no hydrogen 2.745 N/A LYS 47.A N LEU 92.A O no hydrogen 2.840 N/A LYS 47.A NZ GLU 63.A OE1 no hydrogen 3.524 N/A LYS 47.A NZ GLU 63.A OE2 no hydrogen 3.100 N/A LYS 48.A N SER 27.A O no hydrogen 2.920 N/A LYS 48.A NZ GLU 29.A OE2 no hydrogen 2.580 N/A HIS 56.A N THR 53.A OG1 no hydrogen 2.975 N/A LEU 57.A N THR 53.A O no hydrogen 2.916 N/A ARG 58.A N GLU 54.A O no hydrogen 3.179 N/A ASP 59.A N GLU 55.A O no hydrogen 3.011 N/A PHE 60.A N HIS 56.A O no hydrogen 2.897 N/A GLU 61.A N LEU 57.A O no hydrogen 2.805 N/A ARG 62.A N ARG 58.A O no hydrogen 3.093 N/A ARG 62.A NH2 ASP 59.A OD1 no hydrogen 2.816 N/A GLU 63.A N ASP 59.A O no hydrogen 2.951 N/A ILE 64.A N PHE 60.A O no hydrogen 2.938 N/A GLU 65.A N GLU 61.A O no hydrogen 3.012 N/A ILE 66.A N ARG 62.A O no hydrogen 2.893 N/A LEU 67.A N GLU 63.A O no hydrogen 2.891 N/A LYS 68.A N ILE 64.A O no hydrogen 2.874 N/A SER 69.A N GLU 65.A O no hydrogen 3.069 N/A SER 69.A N ILE 66.A O no hydrogen 3.131 N/A SER 69.A OG ILE 66.A O no hydrogen 2.603 N/A SER 69.A OG TYR 137.A OH no hydrogen 2.668 N/A LEU 70.A N LEU 67.A O no hydrogen 3.157 N/A GLN 71.A N TYR 131.A OH no hydrogen 2.892 N/A ASN 74.A N HIS 72.A ND1 no hydrogen 2.969 N/A ILE 75.A N HIS 72.A O no hydrogen 3.159 N/A VAL 76.A N.A ILE 157.A O no hydrogen 3.051 N/A VAL 76.A N.B ILE 157.A O no hydrogen 3.065 N/A LYS 77.A N GLU 95.A OE1 no hydrogen 2.986 N/A LYS 79.A N ILE 93.A O no hydrogen 2.864 N/A LYS 79.A NZ GLU 42.A OE2 no hydrogen 3.317 N/A GLY 80.A N ILE 93.A O no hydrogen 3.023 N/A VAL 81.A N THR 10.A O no hydrogen 2.823 N/A CYS 82.A N LYS 91.A O no hydrogen 2.887 N/A CYS 82.A SG PHE 12.A O no hydrogen 3.524 N/A ALA 85.A N GLU 14.A OE2 no hydrogen 2.843 N/A GLY 86.A N GLU 14.A OE1 no hydrogen 3.449 N/A ARG 87.A NH1 ARG 87.A O no hydrogen 3.269 N/A ARG 88.A N SER 84.A O no hydrogen 3.008 N/A ARG 88.A N ALA 85.A O no hydrogen 3.228 N/A ARG 88.A NE ALA 85.A O no hydrogen 3.013 N/A ARG 88.A NH2 ALA 85.A O no hydrogen 3.064 N/A LYS 91.A N CYS 82.A O no hydrogen 2.936 N/A LEU 92.A N LYS 47.A O no hydrogen 2.908 N/A ILE 93.A N GLY 80.A O no hydrogen 2.763 N/A MET 94.A N ALA 45.A O no hydrogen 2.863 N/A GLU 95.A N LYS 77.A O no hydrogen 2.950 N/A TYR 99.A N VAL 149.A O no hydrogen 3.132 N/A GLY 100.A N LEU 97.A O.A no hydrogen 3.166 N/A GLY 100.A N LEU 97.A O.B no hydrogen 3.165 N/A LEU 102.A N ILE 147.A O no hydrogen 2.724 N/A ARG 103.A N THR 144.A O no hydrogen 3.131 N/A ASP 104.A N SER 101.A OG no hydrogen 3.208 N/A TYR 105.A N SER 101.A O no hydrogen 2.884 N/A LEU 106.A N LEU 102.A O no hydrogen 2.908 N/A GLN 107.A N ARG 103.A O no hydrogen 3.368 N/A LYS 108.A N ASP 104.A O no hydrogen 2.787 N/A HIS 109.A N TYR 105.A O no hydrogen 2.831 N/A LYS 110.A NZ GLU 215.A OE2 no hydrogen 2.755 N/A GLU 111.A N GLU 111.A OE1 no hydrogen 3.083 N/A ARG 112.A N HIS 109.A O no hydrogen 3.072 N/A ARG 112.A NE GLU 111.A OE2 no hydrogen 2.985 N/A ARG 112.A NH2 GLU 111.A OE2 no hydrogen 3.206 N/A ILE 113.A N LYS 110.A O no hydrogen 3.203 N/A LYS 117.A N ASP 114.A OD1 no hydrogen 3.058 N/A LYS 117.A NZ GLU 152.A O no hydrogen 2.936 N/A LEU 118.A N ASP 114.A O no hydrogen 3.062 N/A LEU 119.A N HIS 115.A O no hydrogen 2.939 N/A GLN 120.A N ILE 116.A O no hydrogen 3.043 N/A TYR 121.A N LYS 117.A O no hydrogen 2.928 N/A TYR 121.A OH GLU 152.A O no hydrogen 2.727 N/A THR 122.A N LEU 118.A O no hydrogen 2.985 N/A THR 122.A OG1 LEU 118.A O no hydrogen 2.748 N/A SER 123.A N LEU 119.A O no hydrogen 2.939 N/A SER 123.A OG ASP 287.A OD1 no hydrogen 2.574 N/A SER 123.A OG ASP 287.A OD2 no hydrogen 3.476 N/A GLN 124.A N GLN 120.A O no hydrogen 3.083 N/A GLN 124.A NE2 ASN 153.A O no hydrogen 2.785 N/A ILE 125.A N TYR 121.A O no hydrogen 2.958 N/A CYS 126.A N THR 122.A O no hydrogen 3.017 N/A CYS 126.A SG THR 122.A O no hydrogen 3.419 N/A LYS 127.A N SER 123.A O no hydrogen 3.000 N/A LYS 127.A NZ SER 123.A OG no hydrogen 3.335 N/A LYS 127.A NZ ASP 287.A OD2 no hydrogen 2.665 N/A GLY 128.A N GLN 124.A O no hydrogen 2.950 N/A MET 129.A N ILE 125.A O no hydrogen 2.998 N/A GLU 130.A N CYS 126.A O no hydrogen 2.783 N/A TYR 131.A N LYS 127.A O no hydrogen 3.042 N/A LEU 132.A N GLY 128.A O no hydrogen 3.029 N/A GLY 133.A N MET 129.A O no hydrogen 3.079 N/A THR 134.A N GLU 130.A O no hydrogen 3.320 N/A THR 134.A N TYR 131.A O no hydrogen 3.120 N/A THR 134.A OG1 TYR 131.A O no hydrogen 2.705 N/A LYS 135.A N LEU 132.A O no hydrogen 2.997 N/A LYS 135.A NZ SER 69.A O no hydrogen 3.545 N/A ARG 136.A N GLY 133.A O no hydrogen 2.954 N/A ARG 136.A NE LEU 166.A O no hydrogen 3.120 N/A ARG 136.A NH2 PRO 167.A O no hydrogen 2.948 N/A ARG 136.A NH2 GLU 171.A OE1 no hydrogen 3.303 N/A TYR 137.A N LEU 132.A O no hydrogen 3.062 N/A TYR 137.A OH SER 69.A OG no hydrogen 2.668 N/A ILE 138.A N LYS 164.A O no hydrogen 2.811 N/A HIS 139.A N ASP 199.A OD2 no hydrogen 2.804 N/A ARG 140.A N ASP 199.A OD1 no hydrogen 3.038 N/A ARG 140.A NE LEU 162.A O no hydrogen 2.788 N/A ARG 140.A NH1 GLU 175.A OE1 no hydrogen 3.175 N/A ARG 140.A NH2 LEU 162.A O no hydrogen 3.459 N/A ARG 140.A NH2 GLU 175.A OE1 no hydrogen 3.007 N/A ARG 140.A NH2 GLU 175.A OE2 no hydrogen 2.948 N/A THR 144.A N GLU 209.A OE2 no hydrogen 3.001 N/A THR 144.A OG1 GLU 209.A OE1 no hydrogen 2.712 N/A ASN 146.A N ALA 143.A O no hydrogen 2.916 N/A ILE 147.A N THR 144.A O no hydrogen 3.367 N/A LEU 148.A N LYS 156.A O no hydrogen 2.736 N/A VAL 149.A N GLY 100.A O no hydrogen 2.862 N/A GLU 150.A N ARG 154.A O no hydrogen 2.944 N/A ASN 153.A N ASN 151.A OD1 no hydrogen 2.793 N/A ARG 154.A N ASN 151.A O no hydrogen 3.215 N/A VAL 155.A N GLN 124.A OE1 no hydrogen 2.766 N/A LYS 156.A N LEU 148.A O no hydrogen 2.726 N/A LYS 156.A NZ GLU 95.A OE1 no hydrogen 2.690 N/A LYS 156.A NZ GLU 95.A OE2 no hydrogen 3.339 N/A ILE 157.A N ASN 74.A O no hydrogen 2.805 N/A GLY 158.A N ASN 146.A O no hydrogen 3.046 N/A THR 163.A N PHE 160.A O no hydrogen 3.108 N/A THR 163.A OG1 PHE 160.A O no hydrogen 3.340 N/A LYS 164.A N ILE 138.A O no hydrogen 2.903 N/A LEU 166.A N ARG 136.A O no hydrogen 2.881 N/A LYS 170.A N PRO 167.A O no hydrogen 3.115 N/A VAL 173.A N SER 192.A O no hydrogen 2.963 N/A ILE 181.A N SER 179.A O no hydrogen 2.787 N/A TRP 183.A N PRO 180.A O no hydrogen 3.026 N/A TRP 183.A NE1 GLU 209.A OE2 no hydrogen 2.869 N/A TYR 184.A N ILE 181.A O no hydrogen 3.235 N/A GLU 187.A N GLU 187.A OE1 no hydrogen 2.781 N/A SER 188.A N ALA 185.A O no hydrogen 2.999 N/A SER 188.A OG LYS 193.A O no hydrogen 2.727 N/A LEU 189.A N ALA 185.A O no hydrogen 3.068 N/A THR 190.A N PRO 186.A O no hydrogen 2.887 N/A THR 190.A OG1 PRO 186.A O no hydrogen 3.045 N/A GLU 191.A N GLU 187.A O no hydrogen 2.909 N/A SER 192.A N SER 188.A O no hydrogen 3.110 N/A LYS 193.A N GLU 187.A O no hydrogen 3.319 N/A SER 195.A N SER 198.A OG no hydrogen 2.878 N/A SER 198.A N SER 195.A OG no hydrogen 3.044 N/A SER 198.A OG SER 195.A O no hydrogen 2.965 N/A ASP 199.A N SER 195.A O no hydrogen 3.078 N/A VAL 200.A N VAL 196.A O no hydrogen 2.961 N/A TRP 201.A N ALA 197.A O no hydrogen 3.064 N/A SER 202.A N SER 198.A O no hydrogen 3.037 N/A SER 202.A OG TRP 183.A O no hydrogen 2.670 N/A SER 202.A OG SER 198.A O no hydrogen 3.389 N/A PHE 203.A N ASP 199.A O no hydrogen 2.765 N/A GLY 204.A N VAL 200.A O no hydrogen 3.046 N/A VAL 205.A N TRP 201.A O no hydrogen 3.315 N/A VAL 206.A N SER 202.A O no hydrogen 2.913 N/A LEU 207.A N PHE 203.A O no hydrogen 2.860 N/A TYR 208.A N GLY 204.A O no hydrogen 2.974 N/A TYR 208.A OH LYS 218.A O no hydrogen 2.677 N/A GLU 209.A N VAL 205.A O no hydrogen 2.791 N/A LEU 210.A N VAL 206.A O no hydrogen 2.900 N/A PHE 211.A N LEU 207.A O no hydrogen 3.137 N/A THR 212.A N TYR 208.A O no hydrogen 3.016 N/A THR 212.A N GLU 209.A O no hydrogen 3.243 N/A THR 212.A OG1 TYR 208.A O no hydrogen 3.540 N/A THR 212.A OG1 GLU 209.A O no hydrogen 2.691 N/A TYR 213.A N LEU 210.A O no hydrogen 3.130 N/A TYR 213.A OH ILE 113.A O no hydrogen 3.017 N/A GLU 215.A N THR 212.A O no hydrogen 3.007 N/A LYS 218.A N GLU 215.A O no hydrogen 2.762 N/A ALA 222.A N SER 219.A OG no hydrogen 3.184 N/A GLU 223.A N SER 219.A O no hydrogen 2.896 N/A PHE 224.A N PRO 220.A O no hydrogen 2.906 N/A MET 225.A N PRO 221.A O no hydrogen 2.922 N/A ARG 226.A N ALA 222.A O no hydrogen 3.058 N/A ARG 226.A NH1 SER 217.A O no hydrogen 3.181 N/A ARG 226.A NH2 SER 217.A O no hydrogen 2.451 N/A MET 227.A N GLU 223.A O no hydrogen 3.027 N/A ILE 228.A N PHE 224.A O no hydrogen 2.790 N/A GLY 229.A N MET 225.A O no hydrogen 2.738 N/A LYS 232.A N GLY 229.A O no hydrogen 3.165 N/A LYS 232.A NZ ILE 228.A O no hydrogen 2.834 N/A ILE 237.A N GLY 234.A O no hydrogen 3.155 N/A PHE 239.A N GLN 235.A O no hydrogen 2.897 N/A HIS 240.A N MET 236.A O no hydrogen 3.061 N/A LEU 241.A N ILE 237.A O no hydrogen 2.849 N/A ILE 242.A N VAL 238.A O no hydrogen 2.964 N/A GLU 243.A N PHE 239.A O no hydrogen 3.174 N/A LEU 244.A N HIS 240.A O no hydrogen 2.852 N/A LEU 245.A N LEU 241.A O no hydrogen 2.967 N/A LYS 246.A N ILE 242.A O no hydrogen 2.905 N/A ASN 247.A N GLU 243.A O no hydrogen 3.304 N/A ASN 247.A N LEU 244.A O no hydrogen 3.307 N/A ASN 247.A ND2 GLU 243.A O no hydrogen 3.075 N/A ASN 248.A N LEU 245.A O no hydrogen 3.213 N/A GLY 249.A N LEU 244.A O no hydrogen 2.852 N/A ARG 250.A NE TRP 269.A O no hydrogen 3.046 N/A ARG 250.A NH1 LEU 245.A O no hydrogen 2.921 N/A ARG 250.A NH1 GLY 249.A O no hydrogen 2.919 N/A ARG 250.A NH2 TRP 269.A O no hydrogen 2.798 N/A ARG 250.A NH2 ASN 271.A OD1 no hydrogen 2.909 N/A ARG 253.A NH1 CYS 257.A O no hydrogen 2.967 N/A CYS 257.A N PRO 254.A O no hydrogen 3.077 N/A CYS 257.A SG PRO 258.A O no hydrogen 3.592 N/A TYR 262.A N PRO 258.A O no hydrogen 3.080 N/A TYR 262.A OH LEU 251.A O no hydrogen 2.626 N/A MET 263.A N ASP 259.A O no hydrogen 2.800 N/A ILE 264.A N GLU 260.A O no hydrogen 3.265 N/A MET 265.A N ILE 261.A O no hydrogen 3.199 N/A THR 266.A N TYR 262.A O no hydrogen 2.937 N/A THR 266.A OG1 TYR 262.A O no hydrogen 3.563 N/A THR 266.A OG1 MET 263.A O no hydrogen 3.070 N/A GLU 267.A N MET 263.A O no hydrogen 3.036 N/A CYS 268.A N ILE 264.A O no hydrogen 3.062 N/A CYS 268.A SG ILE 264.A O no hydrogen 3.422 N/A TRP 269.A N MET 265.A O no hydrogen 2.995 N/A ASN 270.A ND2 GLN 275.A OE1 no hydrogen 3.187 N/A ASN 271.A ND2 LEU 245.A O no hydrogen 3.256 N/A ASN 272.A N ASN 270.A OD1 no hydrogen 2.894 N/A ASN 274.A N ASN 272.A OD1 no hydrogen 3.221 N/A GLN 275.A N ASN 272.A O no hydrogen 3.091 N/A ARG 276.A N VAL 273.A O no hydrogen 3.286 N/A ARG 276.A NE ASN 270.A O no hydrogen 2.728 N/A ARG 276.A NH1 GLU 187.A OE2 no hydrogen 2.800 N/A ARG 276.A NH1 ALA 197.A O no hydrogen 3.023 N/A ARG 276.A NH2 GLU 187.A OE1 no hydrogen 2.899 N/A ARG 276.A NH2 ASN 270.A O no hydrogen 2.934 N/A SER 278.A N ASP 281.A OD2 no hydrogen 2.982 N/A ASP 281.A N SER 278.A OG no hydrogen 2.962 N/A LEU 282.A N SER 278.A O no hydrogen 3.031 N/A ALA 283.A N PHE 279.A O no hydrogen 2.911 N/A LEU 284.A N ARG 280.A O no hydrogen 3.089 N/A ARG 285.A N ASP 281.A O no hydrogen 2.999 N/A VAL 286.A N LEU 282.A O no hydrogen 2.849 N/A ASP 287.A N ALA 283.A O no hydrogen 2.903 N/A GLN 288.A N LEU 284.A O no hydrogen 2.908 N/A ILE 289.A N ARG 285.A O no hydrogen 2.946 N/A ARG 290.A N VAL 286.A O no hydrogen 2.980 N/A ARG 290.A NH1 ASP 287.A OD1 no hydrogen 2.961 N/A ASP 291.A N ASP 287.A O no hydrogen 2.782 N/A ASN 292.A N GLN 288.A O no hydrogen 2.880 N/A