Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5x5g_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 4.A N GLY 1.A O no hydrogen 2.953 N/A LEU 5.A N GLY 1.A O no hydrogen 3.133 N/A LYS 6.A N THR 2.A O no hydrogen 2.920 N/A LYS 6.A NZ ASN 34.A O no hydrogen 2.680 N/A ASN 7.A N ASP 3.A O no hydrogen 2.955 N/A SER 8.A N SER 4.A O no hydrogen 2.849 N/A SER 8.A OG SER 4.A O no hydrogen 3.184 N/A ILE 9.A N LEU 5.A O no hydrogen 2.923 N/A GLU 10.A N LYS 6.A O no hydrogen 3.015 N/A LYS 11.A N ASN 7.A O no hydrogen 2.931 N/A TYR 12.A N SER 8.A O no hydrogen 2.957 N/A LEU 13.A N ILE 9.A O no hydrogen 2.998 N/A LEU 13.A N GLU 10.A O no hydrogen 3.131 N/A LYS 14.A N LYS 11.A O no hydrogen 3.153 N/A LYS 16.A N LEU 13.A O no hydrogen 2.984 N/A LYS 16.A NZ TYR 12.A O no hydrogen 2.862 N/A LYS 16.A NZ ASP 15.A OD1 no hydrogen 2.827 N/A LYS 17.A N GLU 253.A OE2 no hydrogen 2.813 N/A ALA 18.A N LYS 16.A O no hydrogen 2.928 N/A LYS 19.A N SER 249.A O no hydrogen 2.886 N/A GLY 21.A N TYR 247.A O no hydrogen 2.759 N/A VAL 22.A N VAL 35.A O no hydrogen 2.951 N/A ALA 23.A N ALA 245.A O no hydrogen 3.016 N/A VAL 24.A N LEU 33.A O no hydrogen 2.744 N/A LEU 25.A N ALA 243.A O no hydrogen 2.883 N/A GLY 26.A N PHE 31.A O no hydrogen 2.810 N/A ILE 27.A N HIS 241.A O no hydrogen 2.965 N/A GLU 28.A N GLU 28.A OE1 no hydrogen 2.866 N/A PHE 31.A N ASP 29.A OD1 no hydrogen 2.848 N/A LEU 33.A N VAL 24.A O no hydrogen 2.975 N/A VAL 35.A N VAL 22.A O no hydrogen 2.858 N/A ASN 36.A ND2 VAL 20.A O no hydrogen 2.868 N/A GLU 37.A N GLU 37.A OE1 no hydrogen 2.720 N/A TYR 41.A N THR 160.A O no hydrogen 2.847 N/A TYR 41.A OH ASN 36.A O no hydrogen 2.611 N/A MET 43.A N ASN 158.A O no hydrogen 2.948 N/A GLN 44.A NE2 GLN 155.A OE1 no hydrogen 2.902 N/A SER 45.A OG SER 109.A OG no hydrogen 3.132 N/A THR 46.A N MET 43.A O no hydrogen 3.112 N/A THR 46.A OG1 MET 43.A O no hydrogen 2.604 N/A TYR 47.A N GLN 44.A O no hydrogen 3.409 N/A TYR 47.A OH ALA 143.A O no hydrogen 2.685 N/A LYS 48.A N SER 45.A O no hydrogen 2.978 N/A LYS 48.A NZ SER 45.A OG no hydrogen 3.159 N/A LYS 48.A NZ SER 109.A O no hydrogen 2.829 N/A LYS 48.A NZ SER 109.A OG no hydrogen 3.387 N/A LYS 48.A NZ ASN 111.A OD1 no hydrogen 2.733 N/A PHE 49.A N THR 46.A O no hydrogen 3.175 N/A HIS 50.A N HIS 50.A ND1 no hydrogen 2.809 N/A LEU 51.A N TYR 47.A O no hydrogen 2.975 N/A ALA 52.A N LYS 48.A O no hydrogen 2.954 N/A LEU 53.A N PHE 49.A O no hydrogen 2.988 N/A ALA 54.A N HIS 50.A O no hydrogen 3.090 N/A VAL 55.A N LEU 51.A O no hydrogen 2.875 N/A LEU 56.A N ALA 52.A O no hydrogen 2.939 N/A ASP 57.A N LEU 53.A O no hydrogen 2.996 N/A LYS 58.A N ALA 54.A O no hydrogen 2.970 N/A LYS 58.A NZ GLU 62.A OE2 no hydrogen 2.870 N/A LEU 59.A N VAL 55.A O no hydrogen 2.851 N/A ASP 60.A N LEU 56.A O no hydrogen 2.884 N/A LYS 61.A N ASP 57.A O no hydrogen 2.838 N/A LYS 61.A NZ ASP 57.A OD1 no hydrogen 2.920 N/A GLU 62.A N LYS 58.A O no hydrogen 3.073 N/A ASN 63.A N ASP 60.A O no hydrogen 3.046 N/A ILE 64.A N LEU 59.A O no hydrogen 2.767 N/A ASP 67.A N SER 65.A OG no hydrogen 3.054 N/A LYS 68.A N SER 65.A O no hydrogen 3.111 N/A LEU 70.A N LEU 96.A O no hydrogen 2.808 N/A VAL 72.A N LEU 94.A O no hydrogen 2.839 N/A LYS 73.A N ASP 76.A OD2 no hydrogen 2.942 N/A LYS 74.A N ASN 93.A OD1 no hydrogen 2.889 N/A ASP 76.A N LYS 73.A O no hydrogen 2.942 N/A LEU 77.A N LYS 74.A O no hydrogen 2.981 N/A GLN 78.A N ASN 112.A OD1 no hydrogen 3.107 N/A GLN 78.A NE2 GLU 146.A OE2 no hydrogen 3.450 N/A ASN 80.A ND2 GLN 78.A OE1 no hydrogen 3.393 N/A TRP 82.A NE1 HIS 108.A O no hydrogen 2.653 N/A SER 83.A OG ASP 110.A OD1 no hydrogen 3.076 N/A SER 83.A OG ASP 110.A OD2 no hydrogen 2.762 N/A LEU 85.A N ASP 110.A OD2 no hydrogen 2.688 N/A LYS 86.A N SER 83.A OG no hydrogen 3.072 N/A LYS 86.A NZ LEU 77.A O no hydrogen 3.038 N/A ASP 87.A N SER 83.A O no hydrogen 3.188 N/A LYS 88.A N PRO 84.A O no hydrogen 2.931 N/A LYS 88.A NZ TYR 89.A OH no hydrogen 3.255 N/A TYR 89.A N LEU 85.A O no hydrogen 2.791 N/A TYR 89.A OH GLU 100.A OE2 no hydrogen 2.568 N/A GLY 92.A N TYR 89.A O no hydrogen 2.985 N/A LEU 94.A N VAL 72.A O no hydrogen 3.140 N/A LEU 96.A N LEU 70.A O no hydrogen 2.828 N/A PHE 98.A N LYS 68.A O no hydrogen 2.986 N/A SER 99.A N VAL 66.A O no hydrogen 2.963 N/A GLU 100.A N SER 97.A OG no hydrogen 3.094 N/A ILE 101.A N SER 97.A O no hydrogen 2.996 N/A ILE 102.A N PHE 98.A O no hydrogen 2.756 N/A LYS 103.A N SER 99.A O no hydrogen 2.957 N/A SER 104.A N GLU 100.A O no hydrogen 3.107 N/A THR 105.A N ILE 101.A O no hydrogen 2.879 N/A THR 105.A OG1 ILE 101.A O no hydrogen 2.834 N/A VAL 106.A N ILE 102.A O no hydrogen 2.866 N/A SER 107.A N LYS 103.A O no hydrogen 2.790 N/A SER 107.A OG THR 189.A O no hydrogen 2.610 N/A HIS 108.A N SER 104.A O no hydrogen 3.168 N/A SER 109.A OG SER 45.A OG no hydrogen 3.132 N/A ASP 110.A N SER 104.A O no hydrogen 3.017 N/A ASN 111.A N TRP 82.A O no hydrogen 3.018 N/A ASN 111.A ND2 THR 81.A OG1 no hydrogen 2.658 N/A ASN 112.A ND2 GLN 78.A O no hydrogen 3.013 N/A ASN 112.A ND2 SER 83.A OG no hydrogen 3.012 N/A GLY 113.A N ASP 110.A OD1 no hydrogen 2.749 N/A CYS 114.A N ASP 110.A O no hydrogen 3.144 N/A CYS 114.A SG ASP 115.A OD1 no hydrogen 3.816 N/A ASP 115.A N ASN 111.A O no hydrogen 3.233 N/A ILE 116.A N ASN 112.A O no hydrogen 2.921 N/A LEU 117.A N GLY 113.A O no hydrogen 2.985 N/A PHE 118.A N CYS 114.A O no hydrogen 2.858 N/A ARG 119.A N ASP 115.A O no hydrogen 3.075 N/A ARG 119.A NH2 ASP 76.A OD1 no hydrogen 3.046 N/A PHE 120.A N ILE 116.A O no hydrogen 2.925 N/A VAL 121.A N LEU 117.A O no hydrogen 2.865 N/A GLY 122.A N PHE 118.A O no hydrogen 2.954 N/A GLY 122.A N ARG 119.A O no hydrogen 3.236 N/A GLY 123.A N PHE 118.A O no hydrogen 2.834 N/A LYS 126.A N GLY 123.A O no hydrogen 3.228 N/A HIS 128.A N THR 124.A O no hydrogen 2.920 N/A ASN 129.A N ASN 125.A O no hydrogen 2.918 N/A ASN 129.A ND2 ASN 125.A OD1 no hydrogen 3.124 N/A PHE 130.A N LYS 126.A O no hydrogen 3.041 N/A ILE 131.A N VAL 127.A O no hydrogen 3.006 N/A SER 132.A N HIS 128.A O no hydrogen 3.044 N/A LYS 133.A N ASN 129.A O no hydrogen 2.741 N/A LEU 134.A N ILE 131.A O no hydrogen 2.972 N/A GLY 135.A N SER 132.A O no hydrogen 2.899 N/A SER 140.A N TRP 159.A O no hydrogen 2.881 N/A SER 140.A OG THR 157.A O no hydrogen 2.665 N/A ILE 141.A N HIS 128.A ND1 no hydrogen 3.063 N/A LYS 142.A N ASN 158.A OD1 no hydrogen 2.757 N/A ALA 143.A N ASN 158.A OD1 no hydrogen 2.982 N/A THR 144.A N GLU 147.A OE1 no hydrogen 2.891 N/A GLU 145.A N ASP 115.A OD1 no hydrogen 2.830 N/A GLU 146.A N ASP 115.A OD2 no hydrogen 2.802 N/A GLU 147.A N THR 144.A OG1 no hydrogen 3.076 N/A MET 148.A N THR 144.A O no hydrogen 3.005 N/A HIS 149.A N GLU 145.A O no hydrogen 3.021 N/A LYS 150.A N GLU 147.A O no hydrogen 3.270 N/A LYS 150.A NZ GLU 146.A OE2 no hydrogen 3.427 N/A VAL 154.A N ALA 151.A O no hydrogen 3.018 N/A GLN 155.A NE2 TRP 152.A O no hydrogen 2.869 N/A TYR 156.A N ASN 153.A O no hydrogen 3.029 N/A TYR 156.A OH ASP 250.A OD1 no hydrogen 2.396 N/A THR 157.A N VAL 154.A O no hydrogen 2.956 N/A THR 157.A OG1 VAL 154.A O no hydrogen 2.612 N/A ASN 158.A N GLN 155.A O no hydrogen 3.132 N/A ASN 158.A ND2 ALA 143.A O no hydrogen 2.953 N/A TRP 159.A N SER 140.A O no hydrogen 3.057 N/A THR 160.A N TYR 41.A O no hydrogen 2.960 N/A THR 160.A OG1 THR 161.A O no hydrogen 2.641 N/A THR 160.A OG1 THR 165.A OG1 no hydrogen 3.384 N/A THR 161.A N ASN 138.A O no hydrogen 3.051 N/A THR 161.A OG1 ASP 163.A OD1 no hydrogen 2.945 N/A ALA 164.A N THR 161.A OG1 no hydrogen 3.276 N/A THR 165.A OG1 THR 160.A OG1 no hydrogen 3.384 N/A THR 165.A OG1 THR 161.A O no hydrogen 3.373 N/A THR 165.A OG1 TYR 247.A OH no hydrogen 2.565 N/A VAL 166.A N PRO 162.A O no hydrogen 3.307 N/A GLN 167.A N ASP 163.A O no hydrogen 3.015 N/A LEU 168.A N ALA 164.A O no hydrogen 2.877 N/A LEU 169.A N THR 165.A O no hydrogen 2.877 N/A LYS 170.A N VAL 166.A O no hydrogen 2.986 N/A LYS 170.A NZ GLY 26.A O no hydrogen 2.716 N/A LYS 171.A N GLN 167.A O no hydrogen 3.154 N/A LYS 171.A NZ LEU 134.A O no hydrogen 3.347 N/A PHE 172.A N LEU 168.A O no hydrogen 2.986 N/A TYR 173.A N LEU 169.A O no hydrogen 2.843 N/A TYR 173.A OH HIS 241.A NE2 no hydrogen 2.770 N/A LYS 174.A N LYS 170.A O no hydrogen 2.963 N/A ASN 175.A ND2 LEU 178.A O no hydrogen 2.954 N/A GLU 176.A N LYS 171.A O no hydrogen 2.931 N/A SER 179.A N ASP 60.A OD2 no hydrogen 3.073 N/A SER 179.A OG ASP 60.A OD1 no hydrogen 2.752 N/A SER 179.A OG ASP 60.A OD2 no hydrogen 3.307 N/A SER 179.A OG SER 182.A OG no hydrogen 3.389 N/A SER 182.A N SER 179.A OG no hydrogen 3.328 N/A SER 182.A OG ASP 60.A OD1 no hydrogen 2.481 N/A SER 182.A OG SER 179.A OG no hydrogen 3.389 N/A TYR 183.A N SER 179.A O no hydrogen 2.977 N/A TYR 183.A OH TYR 173.A O no hydrogen 2.912 N/A ASP 184.A N LYS 180.A O no hydrogen 2.977 N/A PHE 185.A N ASN 181.A O no hydrogen 3.051 N/A LEU 186.A N SER 182.A O no hydrogen 2.792 N/A LEU 187.A N TYR 183.A O no hydrogen 2.873 N/A ASN 188.A N ASP 184.A O no hydrogen 2.967 N/A THR 189.A N PHE 185.A O no hydrogen 3.004 N/A THR 189.A OG1 PHE 185.A O no hydrogen 2.718 N/A MET 190.A N LEU 186.A O no hydrogen 2.880 N/A ILE 191.A N LEU 187.A O no hydrogen 3.083 N/A GLU 192.A N ASN 188.A O no hydrogen 2.904 N/A THR 193.A OG1 THR 189.A O no hydrogen 3.378 N/A THR 193.A OG1 MET 190.A O no hydrogen 3.061 N/A THR 193.A OG1 HIS 212.A O no hydrogen 2.908 N/A THR 194.A N SER 107.A O no hydrogen 3.094 N/A THR 194.A OG1 SER 107.A O no hydrogen 3.510 N/A THR 195.A OG1 THR 214.A OG1 no hydrogen 2.659 N/A ARG 199.A N GLY 196.A O no hydrogen 3.086 N/A ARG 199.A NE GLU 259.A OE2 no hydrogen 2.993 N/A ARG 199.A NH1 GLY 215.A O no hydrogen 2.921 N/A ARG 199.A NH1 SER 216.A OG no hydrogen 3.225 N/A ARG 199.A NH1 ASN 229.A O no hydrogen 2.890 N/A ARG 199.A NH2 SER 216.A OG no hydrogen 2.668 N/A ARG 199.A NH2 GLU 259.A OE2 no hydrogen 3.477 N/A LEU 200.A N ASP 230.A OD2 no hydrogen 2.918 N/A GLY 202.A N ARG 199.A O no hydrogen 2.886 N/A LEU 204.A N LYS 201.A O no hydrogen 3.298 N/A THR 208.A N PRO 205.A O no hydrogen 3.125 N/A THR 208.A OG1 PRO 205.A O no hydrogen 2.745 N/A ALA 211.A N ILE 233.A O no hydrogen 2.893 N/A HIS 212.A N MET 190.A O no hydrogen 2.946 N/A HIS 212.A ND1 ASP 230.A OD1 no hydrogen 2.656 N/A LYS 213.A N ILE 231.A O no hydrogen 2.815 N/A LYS 213.A NZ SER 109.A OG no hydrogen 2.869 N/A LYS 213.A NZ THR 214.A O no hydrogen 2.844 N/A THR 214.A OG1 THR 195.A OG1 no hydrogen 2.659 N/A GLY 215.A N ASN 229.A O no hydrogen 3.190 N/A SER 217.A N ALA 227.A O no hydrogen 2.796 N/A SER 217.A OG ASP 218.A O no hydrogen 2.678 N/A SER 217.A OG ALA 227.A O no hydrogen 3.422 N/A THR 219.A OG1 THR 225.A OG1 no hydrogen 2.613 N/A ASN 220.A N ILE 224.A O no hydrogen 3.060 N/A LYS 222.A N ASN 220.A OD1 no hydrogen 2.893 N/A GLY 223.A N ASN 220.A O no hydrogen 3.277 N/A ILE 224.A N ASN 220.A OD1 no hydrogen 3.113 N/A THR 225.A N SER 251.A O no hydrogen 2.830 N/A THR 225.A OG1 THR 219.A OG1 no hydrogen 2.613 N/A ALA 227.A N SER 217.A OG no hydrogen 2.832 N/A THR 228.A N VAL 248.A O no hydrogen 2.840 N/A ASN 229.A N GLY 215.A O no hydrogen 2.824 N/A ASN 229.A ND2 PRO 42.A O no hydrogen 2.893 N/A ASN 229.A ND2 MET 43.A O no hydrogen 2.949 N/A ASP 230.A N VAL 246.A O no hydrogen 3.064 N/A ILE 231.A N LYS 213.A O no hydrogen 3.138 N/A GLY 232.A N ILE 244.A O no hydrogen 2.872 N/A ILE 233.A N ALA 211.A O no hydrogen 2.760 N/A ILE 234.A N PHE 242.A O no hydrogen 2.843 N/A THR 235.A N VAL 209.A O no hydrogen 2.983 N/A LEU 236.A N LYS 240.A O no hydrogen 2.765 N/A GLY 239.A N LEU 236.A O no hydrogen 2.966 N/A LYS 240.A N ASN 238.A OD1 no hydrogen 3.210 N/A HIS 241.A N GLU 28.A OE1 no hydrogen 2.703 N/A HIS 241.A ND1 GLU 28.A OE2 no hydrogen 2.677 N/A PHE 242.A N ILE 234.A O no hydrogen 2.999 N/A ALA 243.A N LEU 25.A O no hydrogen 2.814 N/A ILE 244.A N GLY 232.A O no hydrogen 2.856 N/A ALA 245.A N ALA 23.A O no hydrogen 2.827 N/A VAL 246.A N ASP 230.A O no hydrogen 2.961 N/A TYR 247.A N GLY 21.A O no hydrogen 2.805 N/A TYR 247.A OH THR 165.A OG1 no hydrogen 2.565 N/A VAL 248.A N THR 228.A O no hydrogen 2.859 N/A SER 249.A N LYS 19.A O no hydrogen 2.810 N/A SER 249.A OG LYS 19.A O no hydrogen 2.491 N/A ASP 250.A N ALA 226.A O no hydrogen 2.901 N/A SER 251.A N THR 225.A O no hydrogen 2.962 N/A SER 251.A OG ASN 258.A OD1 no hydrogen 2.650 N/A SER 252.A N LYS 17.A O no hydrogen 2.823 N/A GLU 253.A N SER 251.A OG no hydrogen 2.872 N/A VAL 257.A N LYS 254.A O no hydrogen 2.912 N/A ASN 258.A N LYS 254.A O no hydrogen 3.015 N/A ASN 258.A ND2 GLU 253.A O no hydrogen 3.084 N/A GLU 259.A N SER 255.A O no hydrogen 2.989 N/A LYS 260.A N ASP 256.A O no hydrogen 3.008 N/A ILE 261.A N VAL 257.A O no hydrogen 2.901 N/A ALA 263.A N GLU 259.A O no hydrogen 2.924 N/A GLU 264.A N LYS 260.A O no hydrogen 2.747 N/A ILE 265.A N ILE 261.A O no hydrogen 3.021 N/A CYS 266.A N ILE 262.A O no hydrogen 2.956 N/A CYS 266.A SG LEU 200.A O no hydrogen 3.469 N/A LYS 267.A N ALA 263.A O no hydrogen 2.820 N/A LYS 267.A NZ ASP 271.A OD1 no hydrogen 2.708 N/A LYS 267.A NZ ASP 271.A OD2 no hydrogen 3.383 N/A SER 268.A N GLU 264.A O no hydrogen 2.848 N/A SER 268.A OG ILE 265.A O no hydrogen 2.885 N/A VAL 269.A N ILE 265.A O no hydrogen 3.079 N/A TRP 270.A N CYS 266.A O no hydrogen 2.827 N/A ASP 271.A N LYS 267.A O no hydrogen 2.840 N/A TYR 272.A N SER 268.A O no hydrogen 3.212 N/A LEU 273.A N VAL 269.A O no hydrogen 2.946 N/A VAL 274.A N TRP 270.A O no hydrogen 2.905 N/A LYS 275.A N ASP 271.A O no hydrogen 3.170 N/A