Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5xsr_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG ASP 128.A OD1 no hydrogen 3.438 N/A SER 2.A OG ASP 128.A OD2 no hydrogen 2.568 N/A LYS 3.A N ASP 128.A OD1 no hydrogen 3.449 N/A LEU 4.A N SER 2.A OG no hydrogen 2.837 N/A LYS 6.A NZ ASP 10.A OD2 no hydrogen 3.395 N/A GLN 9.A N PRO 5.A O no hydrogen 3.040 N/A GLN 9.A NE2 LEU 4.A O no hydrogen 2.676 N/A ASP 10.A N LYS 6.A O no hydrogen 2.936 N/A LEU 11.A N PRO 7.A O no hydrogen 2.922 N/A ILE 12.A N VAL 8.A O no hydrogen 3.043 N/A LYS 13.A N GLN 9.A O no hydrogen 2.964 N/A LYS 13.A NZ ASP 10.A OD1 no hydrogen 3.180 N/A MET 14.A N ASP 10.A O no hydrogen 2.873 N/A ILE 15.A N LEU 11.A O no hydrogen 3.043 N/A PHE 16.A N ILE 12.A O no hydrogen 3.123 N/A SER 20.A N ASP 17.A OD1 no hydrogen 2.527 N/A SER 20.A OG ASP 17.A OD1 no hydrogen 2.595 N/A MET 21.A N ASP 17.A O no hydrogen 3.364 N/A LYS 22.A N VAL 18.A O no hydrogen 3.025 N/A LYS 23.A N GLU 19.A O no hydrogen 2.781 N/A ALA 24.A N SER 20.A O no hydrogen 3.024 N/A MET 25.A N MET 21.A O no hydrogen 3.172 N/A VAL 26.A N LYS 22.A O no hydrogen 2.856 N/A GLU 27.A N LYS 23.A O no hydrogen 2.914 N/A TYR 28.A N ALA 24.A O no hydrogen 2.989 N/A TYR 28.A OH ASN 106.A OD1 no hydrogen 2.610 N/A GLU 29.A N VAL 26.A O no hydrogen 2.889 N/A ILE 30.A N MET 25.A O no hydrogen 3.120 N/A ASP 31.A N PRO 80.A O no hydrogen 2.855 N/A GLN 33.A N ASP 31.A OD1 no hydrogen 2.892 N/A LYS 34.A N ASP 31.A OD1 no hydrogen 2.971 N/A LYS 34.A NZ ASP 31.A OD2 no hydrogen 3.564 N/A MET 35.A N ASP 31.A O no hydrogen 2.795 N/A LYS 39.A N PRO 36.A O no hydrogen 3.216 N/A ILE 45.A N SER 41.A O no hydrogen 2.842 N/A GLN 46.A N LYS 42.A O no hydrogen 2.897 N/A ALA 47.A N ARG 43.A O no hydrogen 3.140 N/A ALA 48.A N GLN 44.A O no hydrogen 3.116 N/A TYR 49.A N ILE 45.A O no hydrogen 2.981 N/A TYR 49.A OH ASP 105.A OD1 no hydrogen 2.256 N/A SER 50.A N GLN 46.A O no hydrogen 3.295 N/A ILE 51.A N ALA 47.A O no hydrogen 3.056 N/A LEU 52.A N ALA 48.A O no hydrogen 2.914 N/A SER 53.A N TYR 49.A O no hydrogen 2.855 N/A SER 53.A OG TYR 49.A O no hydrogen 3.392 N/A SER 53.A OG GLU 216.A O no hydrogen 2.476 N/A GLU 54.A N SER 50.A O no hydrogen 2.745 N/A VAL 55.A N ILE 51.A O no hydrogen 2.777 N/A GLN 56.A N LEU 52.A O no hydrogen 2.973 N/A GLN 56.A NE2 GLN 56.A O no hydrogen 2.920 N/A GLN 56.A NE2 SER 60.A OG no hydrogen 3.295 N/A GLN 57.A N SER 53.A O no hydrogen 2.924 N/A ALA 58.A N GLU 54.A O no hydrogen 2.919 N/A VAL 59.A N VAL 55.A O no hydrogen 2.931 N/A SER 60.A N GLN 56.A O no hydrogen 3.002 N/A SER 60.A OG GLN 56.A O no hydrogen 3.326 N/A GLN 61.A N GLN 57.A O no hydrogen 3.153 N/A GLY 62.A N ALA 58.A O no hydrogen 3.131 N/A SER 63.A OG GLN 61.A OE1 no hydrogen 3.417 N/A GLN 67.A N SER 64.A O no hydrogen 2.726 N/A ILE 68.A N SER 64.A O no hydrogen 2.989 N/A LEU 69.A N ASP 65.A O no hydrogen 2.737 N/A ASP 70.A N SER 66.A O no hydrogen 3.126 N/A LEU 71.A N GLN 67.A O no hydrogen 2.974 N/A SER 72.A N ILE 68.A O no hydrogen 2.895 N/A ASN 73.A N LEU 69.A O no hydrogen 2.847 N/A ARG 74.A N ASP 70.A O no hydrogen 2.844 N/A PHE 75.A N LEU 71.A O no hydrogen 2.978 N/A TYR 76.A N SER 72.A O no hydrogen 3.391 N/A TYR 76.A OH PRO 89.A O no hydrogen 2.559 N/A THR 77.A N ASN 73.A O no hydrogen 2.899 N/A THR 77.A OG1 ASN 73.A O no hydrogen 2.695 N/A LEU 78.A N ARG 74.A O no hydrogen 2.973 N/A ILE 79.A N PHE 75.A O no hydrogen 2.703 N/A HIS 81.A ND1 ILE 79.A O no hydrogen 2.826 N/A ASP 82.A N GLU 29.A O no hydrogen 2.875 N/A GLY 84.A N ASP 82.A OD2 no hydrogen 3.103 N/A LYS 86.A N PHE 83.A O no hydrogen 3.143 N/A LEU 91.A N SER 72.A OG no hydrogen 2.725 N/A ASN 93.A ND2 ASN 92.A OD1 no hydrogen 2.925 N/A SER 96.A N ASN 93.A OD1 no hydrogen 3.182 N/A VAL 97.A N ASN 93.A O no hydrogen 3.153 N/A GLN 98.A N ALA 94.A O no hydrogen 2.927 N/A GLN 98.A NE2 GLU 102.A OE2 no hydrogen 2.854 N/A ALA 99.A N ASP 95.A O no hydrogen 3.099 N/A LYS 100.A N SER 96.A O no hydrogen 3.348 N/A ALA 101.A N VAL 97.A O no hydrogen 2.852 N/A GLU 102.A N GLN 98.A O no hydrogen 2.707 N/A MET 103.A N ALA 99.A O no hydrogen 2.929 N/A LEU 104.A N LYS 100.A O no hydrogen 3.073 N/A ASP 105.A N ALA 101.A O no hydrogen 2.921 N/A ASN 106.A N GLU 102.A O no hydrogen 3.218 N/A ASN 106.A ND2 THR 200.A OG1 no hydrogen 3.031 N/A ASN 106.A ND2 ASN 201.A OD1 no hydrogen 2.861 N/A LEU 107.A N MET 103.A O no hydrogen 2.954 N/A LEU 108.A N LEU 104.A O no hydrogen 2.929 N/A ASP 109.A N ASP 105.A O no hydrogen 3.326 N/A ILE 110.A N ASN 106.A O no hydrogen 2.916 N/A GLU 111.A N LEU 107.A O no hydrogen 2.900 N/A VAL 112.A N LEU 108.A O no hydrogen 2.972 N/A ALA 113.A N ASP 109.A O no hydrogen 2.990 N/A TYR 114.A N ILE 110.A O no hydrogen 2.811 N/A SER 115.A N GLU 111.A O no hydrogen 2.808 N/A SER 115.A OG GLU 111.A O no hydrogen 3.056 N/A SER 115.A OG GLU 111.A OE2 no hydrogen 2.450 N/A LEU 116.A N VAL 112.A O no hydrogen 2.896 N/A LEU 117.A N ALA 113.A O no hydrogen 2.830 N/A ARG 118.A N TYR 114.A O no hydrogen 2.929 N/A GLY 119.A N SER 115.A O no hydrogen 2.993 N/A ILE 127.A N ASP 125.A OD1 no hydrogen 3.153 N/A VAL 129.A N ASP 125.A O no hydrogen 2.890 N/A ASN 130.A N PRO 126.A O no hydrogen 2.864 N/A ASN 130.A ND2 PRO 126.A O no hydrogen 2.813 N/A TYR 131.A N ILE 127.A O no hydrogen 2.868 N/A GLU 132.A N ASP 128.A O no hydrogen 3.180 N/A LYS 133.A N ASN 130.A O no hydrogen 3.196 N/A LYS 133.A NZ LEU 116.A O no hydrogen 2.620 N/A LYS 133.A NZ LEU 117.A O no hydrogen 3.237 N/A LYS 133.A NZ GLY 119.A O no hydrogen 2.492 N/A LEU 134.A N TYR 131.A O no hydrogen 2.985 N/A LYS 135.A N GLU 132.A O no hydrogen 3.085 N/A THR 136.A OG1 LEU 134.A O no hydrogen 2.588 N/A ASP 137.A N GLU 173.A O no hydrogen 2.903 N/A ILE 138.A N TYR 131.A OH no hydrogen 3.016 N/A LYS 139.A N LYS 171.A O no hydrogen 2.907 N/A VAL 141.A N ILE 169.A O no hydrogen 2.875 N/A SER 145.A N ASP 142.A O no hydrogen 3.224 N/A SER 145.A OG ASP 142.A O no hydrogen 2.544 N/A ALA 148.A N SER 145.A OG no hydrogen 3.229 N/A GLU 149.A N SER 145.A O no hydrogen 3.139 N/A ILE 150.A N GLU 146.A O no hydrogen 2.829 N/A ILE 151.A N GLU 147.A O no hydrogen 3.018 N/A ARG 152.A N ALA 148.A O no hydrogen 2.739 N/A ARG 152.A NH2 VAL 166.A O no hydrogen 3.218 N/A LYS 153.A N GLU 149.A O no hydrogen 2.892 N/A TYR 154.A N ILE 150.A O no hydrogen 2.918 N/A TYR 154.A OH LEU 192.A O no hydrogen 2.790 N/A VAL 155.A N ILE 151.A O no hydrogen 3.045 N/A LYS 156.A N ARG 152.A O no hydrogen 3.016 N/A ASN 157.A N LYS 153.A O no hydrogen 2.994 N/A ASN 157.A ND2 LEU 304.A O no hydrogen 3.165 N/A THR 158.A N TYR 154.A O no hydrogen 3.358 N/A THR 158.A OG1 TYR 154.A O no hydrogen 2.816 N/A HIS 159.A N LYS 156.A O no hydrogen 3.407 N/A ALA 160.A N SER 235.A OG no hydrogen 2.958 N/A TYR 162.A OH ASN 239.A OD1 no hydrogen 3.178 N/A ASP 163.A N ASN 341.A O no hydrogen 2.745 N/A GLU 165.A N LYS 339.A O no hydrogen 3.072 N/A ILE 167.A N LYS 337.A O no hydrogen 2.820 N/A ASP 168.A N LYS 337.A O no hydrogen 3.467 N/A PHE 170.A N LEU 335.A O no hydrogen 2.871 N/A LYS 171.A N LYS 139.A O no hydrogen 2.744 N/A ILE 172.A N LYS 333.A O no hydrogen 2.876 N/A GLU 173.A N ASP 137.A O no hydrogen 2.955 N/A ARG 174.A NE GLU 177.A OE2 no hydrogen 2.800 N/A ARG 174.A NH2 GLU 177.A OE2 no hydrogen 3.160 N/A GLU 175.A N LYS 135.A O no hydrogen 2.883 N/A GLU 177.A N ARG 174.A O no hydrogen 3.263 N/A ARG 180.A N GLY 176.A O no hydrogen 3.109 N/A TYR 181.A N GLU 177.A O no hydrogen 2.835 N/A TYR 181.A OH GLU 256.A OE2 no hydrogen 2.628 N/A LYS 182.A N GLN 179.A O no hydrogen 3.325 N/A PHE 184.A N TYR 181.A O no hydrogen 2.875 N/A LYS 185.A N TYR 181.A O no hydrogen 3.273 N/A LYS 185.A N LYS 182.A O no hydrogen 3.070 N/A GLN 186.A N PRO 183.A O no hydrogen 3.238 N/A LEU 187.A N PHE 184.A O no hydrogen 3.048 N/A ASN 189.A ND2 GLY 260.A O no hydrogen 3.119 N/A ARG 190.A NE GLU 256.A OE2 no hydrogen 3.361 N/A ARG 191.A N VAL 257.A O no hydrogen 2.978 N/A ARG 191.A NE ASN 189.A OD1 no hydrogen 3.071 N/A ARG 191.A NH2 ASN 189.A OD1 no hydrogen 3.067 N/A LEU 192.A N ASP 301.A O no hydrogen 2.805 N/A LEU 193.A N GLY 255.A O no hydrogen 2.826 N/A TRP 194.A N ALA 231.A O no hydrogen 2.951 N/A HIS 195.A N LEU 253.A O no hydrogen 2.890 N/A HIS 195.A ND1 TYR 229.A O no hydrogen 2.813 N/A ASN 201.A N ARG 198.A O no hydrogen 3.075 N/A ASN 201.A ND2 SER 197.A OG no hydrogen 2.993 N/A PHE 202.A N THR 199.A O no hydrogen 3.093 N/A ILE 205.A N ASN 201.A O no hydrogen 2.927 N/A LEU 206.A N PHE 202.A O no hydrogen 3.078 N/A SER 207.A N ALA 203.A O no hydrogen 3.155 N/A SER 207.A OG ALA 203.A O no hydrogen 3.149 N/A SER 207.A OG GLY 204.A O no hydrogen 3.454 N/A GLN 208.A N GLY 204.A O no hydrogen 2.885 N/A GLY 209.A N ILE 205.A O no hydrogen 2.643 N/A GLU 216.A N GLU 216.A OE1 no hydrogen 2.363 N/A ALA 217.A N PRO 214.A O no hydrogen 3.222 N/A THR 220.A OG1 GLN 56.A OE1 no hydrogen 2.704 N/A TYR 222.A N VAL 219.A O no hydrogen 2.929 N/A PHE 224.A N TYR 229.A OH no hydrogen 2.821 N/A GLY 225.A N TYR 222.A O no hydrogen 3.133 N/A LYS 226.A NZ PRO 214.A O no hydrogen 2.648 N/A LYS 226.A NZ ALA 217.A O no hydrogen 2.661 N/A ILE 228.A N VAL 324.A O no hydrogen 2.992 N/A TYR 229.A OH GLY 225.A O no hydrogen 2.746 N/A PHE 230.A N TYR 322.A O no hydrogen 2.791 N/A ALA 231.A N TRP 194.A O no hydrogen 3.164 N/A VAL 234.A N THR 158.A OG1 no hydrogen 2.890 N/A SER 235.A OG THR 158.A O no hydrogen 3.230 N/A LYS 236.A NZ TYR 319.A O no hydrogen 2.782 N/A LYS 236.A NZ ASN 320.A O no hydrogen 3.006 N/A LYS 236.A NZ GLU 321.A OE2 no hydrogen 2.598 N/A SER 237.A N MET 233.A O no hydrogen 3.430 N/A ALA 238.A N VAL 234.A O no hydrogen 2.770 N/A ASN 239.A N SER 235.A O no hydrogen 3.240 N/A TYR 240.A N SER 237.A O no hydrogen 2.862 N/A CYS 241.A N ALA 238.A O no hydrogen 2.978 N/A CYS 241.A SG SER 197.A O no hydrogen 3.929 N/A CYS 241.A SG LEU 251.A O no hydrogen 3.269 N/A HIS 242.A N ASN 239.A O no hydrogen 3.306 N/A GLY 250.A N LEU 338.A O no hydrogen 2.904 N/A ILE 252.A N LEU 336.A O no hydrogen 3.060 N/A LEU 253.A N HIS 195.A O no hydrogen 2.864 N/A LEU 254.A N TYR 334.A O no hydrogen 2.982 N/A GLY 255.A N LEU 193.A O no hydrogen 2.834 N/A GLU 256.A N ASN 331.A O no hydrogen 2.769 N/A VAL 257.A N ARG 191.A O no hydrogen 2.811 N/A ALA 258.A N GLN 329.A O no hydrogen 3.039 N/A LEU 259.A N ASN 189.A O no hydrogen 3.009 N/A GLY 260.A N HIS 188.A O no hydrogen 3.212 N/A TYR 263.A N SER 280.A O no hydrogen 2.704 N/A LEU 265.A N LYS 282.A O no hydrogen 2.907 N/A SER 269.A N MET 223.A O no hydrogen 3.020 N/A LYS 278.A N PRO 275.A O no hydrogen 3.019 N/A LYS 278.A NZ MET 262.A O no hydrogen 3.022 N/A HIS 279.A N ASN 261.A O no hydrogen 2.809 N/A SER 280.A OG LEU 259.A O no hydrogen 3.015 N/A VAL 281.A N ILE 323.A O no hydrogen 2.966 N/A LYS 282.A N TYR 263.A O no hydrogen 3.054 N/A GLY 283.A N GLU 321.A O no hydrogen 2.778 N/A LEU 284.A N LEU 265.A O no hydrogen 2.971 N/A GLY 285.A N ASN 320.A OD1 no hydrogen 2.942 N/A LYS 286.A N LEU 317.A O no hydrogen 2.807 N/A THR 287.A N LEU 318.A O no hydrogen 2.886 N/A THR 288.A N ILE 308.A O no hydrogen 2.968 N/A ASP 290.A N THR 306.A O no hydrogen 2.883 N/A SER 292.A N ASP 290.A OD1 no hydrogen 3.102 N/A SER 292.A OG ASP 290.A OD1 no hydrogen 3.146 N/A SER 292.A OG ASP 290.A OD2 no hydrogen 3.219 N/A ALA 293.A N ASP 290.A O no hydrogen 3.142 N/A ASN 294.A N PRO 291.A O no hydrogen 3.477 N/A ASN 294.A ND2 ASP 301.A OD1 no hydrogen 3.135 N/A ILE 295.A N VAL 302.A O no hydrogen 3.281 N/A LEU 297.A N VAL 300.A O no hydrogen 3.063 N/A VAL 300.A N LEU 297.A O no hydrogen 3.201 N/A ASP 301.A N ARG 190.A O no hydrogen 3.135 N/A VAL 302.A N ILE 295.A O no hydrogen 2.785 N/A LEU 304.A N VAL 302.A O no hydrogen 3.059 N/A ILE 308.A N THR 288.A O no hydrogen 2.854 N/A SER 310.A N LYS 286.A O no hydrogen 2.787 N/A SER 310.A OG GLY 285.A O no hydrogen 2.585 N/A SER 310.A OG LYS 286.A O no hydrogen 2.869 N/A VAL 312.A N SER 310.A OG no hydrogen 3.277 N/A ASN 320.A ND2 ASP 232.A OD2 no hydrogen 2.690 N/A ASN 320.A ND2 THR 288.A OG1 no hydrogen 3.036 N/A GLU 321.A N GLY 283.A O no hydrogen 3.096 N/A TYR 322.A N PHE 230.A O no hydrogen 2.809 N/A TYR 322.A OH ASP 232.A OD2 no hydrogen 2.837 N/A ILE 323.A N VAL 281.A O no hydrogen 2.962 N/A VAL 324.A N ILE 228.A O no hydrogen 3.172 N/A TYR 325.A OH PHE 224.A O no hydrogen 2.701 N/A ALA 328.A N ASP 326.A OD1 no hydrogen 2.994 N/A GLN 329.A N ASP 326.A O no hydrogen 3.133 N/A GLN 329.A NE2 ALA 258.A O no hydrogen 2.827 N/A GLN 329.A NE2 HIS 279.A O no hydrogen 2.968 N/A ASN 331.A N GLU 256.A O no hydrogen 2.807 N/A LEU 332.A N GLU 177.A OE1 no hydrogen 2.901 N/A LYS 333.A N LEU 254.A O no hydrogen 2.972 N/A LYS 333.A NZ ASN 331.A OD1 no hydrogen 3.219 N/A TYR 334.A N LEU 254.A O no hydrogen 3.162 N/A TYR 334.A OH GLU 147.A OE1 no hydrogen 2.653 N/A LEU 335.A N PHE 170.A O no hydrogen 2.838 N/A LEU 336.A N ILE 252.A O no hydrogen 2.861 N/A LYS 337.A N ASP 168.A O no hydrogen 2.915 N/A LEU 338.A N GLY 250.A O no hydrogen 2.767 N/A LYS 339.A N GLU 165.A O no hydrogen 2.813 N/A LYS 339.A NZ ASN 341.A OD1 no hydrogen 2.631 N/A PHE 340.A N PRO 248.A O no hydrogen 2.651 N/A ASN 341.A N ASP 163.A O no hydrogen 2.762 N/A ASN 341.A ND2 GLU 165.A OE1 no hydrogen 3.511 N/A LYS 343.A N ALA 161.A O no hydrogen 3.367 N/A