Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5xyx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A NH2 PRO 83.A O no hydrogen 2.706 N/A TYR 6.A N VAL 17.A O no hydrogen 3.004 N/A TYR 6.A OH TYR 21.A O no hydrogen 2.582 N/A ARG 7.A NH1 GLU 16.A OE1 no hydrogen 3.391 N/A LEU 10.A N THR 13.A O no hydrogen 2.863 N/A TRP 15.A N GLN 8.A O no hydrogen 2.789 N/A GLU 16.A N TYR 94.A OH no hydrogen 3.059 N/A VAL 17.A N TYR 6.A O no hydrogen 3.099 N/A GLU 19.A N THR 4.A O no hydrogen 3.061 N/A ARG 20.A NE ASP 34.A OD1 no hydrogen 2.820 N/A ARG 20.A NH2 ASP 34.A OD1 no hydrogen 3.029 N/A ARG 20.A NH2 ASP 34.A OD2 no hydrogen 2.657 N/A TYR 21.A N PRO 18.A O no hydrogen 2.972 N/A TYR 21.A OH ASP 79.A OD2 no hydrogen 2.647 N/A GLN 22.A N PHE 33.A O no hydrogen 2.934 N/A GLN 22.A NE2 GLU 19.A O no hydrogen 3.032 N/A SER 25.A N ALA 31.A O no hydrogen 3.231 N/A VAL 27.A N VAL 29.A O no hydrogen 2.773 N/A SER 28.A OG ASN 11.A OD1.B no hydrogen 2.963 N/A CYS 30.A N VAL 43.A O no hydrogen 2.809 N/A ALA 31.A N SER 25.A O no hydrogen 3.019 N/A ALA 32.A N VAL 41.A O no hydrogen 2.768 N/A PHE 33.A N GLN 22.A O no hydrogen 2.766 N/A ASP 34.A N LEU 39.A O no hydrogen 2.998 N/A THR 35.A N ARG 20.A O no hydrogen 3.003 N/A THR 35.A OG1 ARG 20.A O no hydrogen 2.795 N/A LYS 36.A N ASP 34.A OD1 no hydrogen 3.292 N/A THR 37.A N ASP 34.A O no hydrogen 3.253 N/A THR 37.A OG1 ASP 34.A OD2 no hydrogen 2.588 N/A GLY 38.A N ASP 34.A O no hydrogen 2.761 N/A LEU 39.A N THR 37.A OG1 no hydrogen 3.348 N/A VAL 41.A N ALA 32.A O no hydrogen 2.802 N/A ALA 42.A N THR 97.A O no hydrogen 2.718 N/A VAL 43.A N CYS 30.A O no hydrogen 2.779 N/A LYS 44.A N LEU 95.A O no hydrogen 2.944 N/A LYS 44.A NZ GLU 62.A OE2 no hydrogen 3.120 N/A LYS 45.A N SER 28.A O no hydrogen 3.152 N/A LYS 45.A NZ ILE 14.A O no hydrogen 2.578 N/A LEU 46.A N VAL 93.A O no hydrogen 2.975 N/A HIS 55.A N SER 52.A OG no hydrogen 3.105 N/A ALA 56.A N SER 52.A O no hydrogen 2.928 N/A LYS 57.A N ILE 53.A O no hydrogen 3.002 N/A LYS 57.A NZ GLU 312.A O no hydrogen 2.778 N/A LYS 57.A NZ ARG 314.A O no hydrogen 3.246 N/A ARG 58.A N ILE 54.A O no hydrogen 3.031 N/A THR 59.A N HIS 55.A O no hydrogen 3.024 N/A THR 59.A OG1 PRO 49.A O no hydrogen 2.974 N/A THR 59.A OG1 HIS 55.A O no hydrogen 2.865 N/A TYR 60.A N ALA 56.A O no hydrogen 3.132 N/A ARG 61.A N LYS 57.A O no hydrogen 2.808 N/A ARG 61.A NE GLU 312.A OE1 no hydrogen 3.424 N/A ARG 61.A NE GLU 312.A OE2 no hydrogen 2.817 N/A ARG 61.A NH2 GLU 312.A OE1 no hydrogen 2.799 N/A GLU 62.A N ARG 58.A O no hydrogen 2.816 N/A LEU 63.A N THR 59.A O no hydrogen 3.045 N/A ARG 64.A N TYR 60.A O no hydrogen 2.825 N/A ARG 64.A NH1 TYR 60.A OH no hydrogen 3.071 N/A ARG 64.A NH2 ASP 308.A O no hydrogen 2.823 N/A LEU 65.A N ARG 61.A O no hydrogen 3.005 N/A LEU 66.A N GLU 62.A O no hydrogen 3.146 N/A LYS 67.A N LEU 63.A O no hydrogen 3.033 N/A LYS 67.A NZ GLU 328.A O no hydrogen 2.847 N/A LYS 67.A NZ GLU 328.A OE1 no hydrogen 2.737 N/A HIS 68.A N ARG 64.A O no hydrogen 3.135 N/A HIS 68.A N LEU 65.A O no hydrogen 3.101 N/A HIS 68.A NE2 ASP 305.A O no hydrogen 3.006 N/A MET 69.A N LEU 65.A O no hydrogen 3.268 N/A LYS 70.A N TYR 127.A OH no hydrogen 3.010 N/A ASN 73.A N HIS 71.A ND1 no hydrogen 3.180 N/A ASN 73.A ND2 GLN 120.A OE1 no hydrogen 3.219 N/A ASN 73.A ND2 LEU 151.A O no hydrogen 2.835 N/A VAL 74.A N HIS 71.A O no hydrogen 3.160 N/A ILE 75.A N ILE 153.A O no hydrogen 3.084 N/A LEU 78.A N VAL 96.A O no hydrogen 2.784 N/A ASP 79.A N VAL 96.A O no hydrogen 3.303 N/A PHE 81.A N TYR 94.A O no hydrogen 3.160 N/A THR 82.A OG1 ASP 92.A O no hydrogen 2.635 N/A ARG 85.A N GLU 89.A OE1 no hydrogen 3.515 N/A SER 86.A OG GLU 88.A OE1 no hydrogen 3.146 N/A SER 86.A OG GLU 89.A OE2 no hydrogen 3.210 N/A PHE 90.A N LEU 87.A O no hydrogen 3.217 N/A TYR 94.A N PHE 81.A O no hydrogen 3.097 N/A LEU 95.A N LYS 44.A O no hydrogen 2.822 N/A VAL 96.A N ASP 79.A O no hydrogen 2.760 N/A THR 97.A N ALA 42.A O no hydrogen 2.999 N/A THR 97.A OG1 HIS 98.A O no hydrogen 3.272 N/A LEU 99.A N ARG 40.A O no hydrogen 3.066 N/A ALA 102.A N VAL 145.A O no hydrogen 3.111 N/A LEU 104.A N PRO 140.A O no hydrogen 3.038 N/A ASN 106.A N ASP 103.A OD1 no hydrogen 3.096 N/A VAL 108.A N LEU 104.A O no hydrogen 3.418 N/A VAL 108.A N ASN 105.A O no hydrogen 3.129 N/A THR 110.A OG1 HIS 113.A ND1 no hydrogen 2.888 N/A HIS 113.A N THR 110.A OG1 no hydrogen 3.294 N/A VAL 114.A N THR 110.A O no hydrogen 3.052 N/A GLN 115.A N ASP 111.A O no hydrogen 2.942 N/A GLN 115.A NE2 ASP 111.A O no hydrogen 3.446 N/A GLN 115.A NE2 ASP 111.A OD2 no hydrogen 3.385 N/A PHE 116.A N ASP 112.A O no hydrogen 3.092 N/A LEU 117.A N HIS 113.A O no hydrogen 3.004 N/A ILE 118.A N VAL 114.A O no hydrogen 2.880 N/A TYR 119.A N GLN 115.A O no hydrogen 2.813 N/A TYR 119.A OH GLU 301.A OE2 no hydrogen 2.431 N/A GLN 120.A N PHE 116.A O no hydrogen 3.126 N/A GLN 120.A NE2 PHE 116.A O no hydrogen 3.133 N/A GLN 120.A NE2 CYS 149.A O no hydrogen 2.901 N/A ILE 121.A N LEU 117.A O no hydrogen 3.055 N/A LEU 122.A N ILE 118.A O no hydrogen 3.025 N/A ARG 123.A N TYR 119.A O no hydrogen 2.896 N/A ARG 123.A NE ASP 300.A O no hydrogen 2.710 N/A ARG 123.A NH1 GLU 72.A OE2 no hydrogen 3.010 N/A ARG 123.A NH1 ASN 73.A OD1 no hydrogen 2.942 N/A ARG 123.A NH2 GLU 72.A OE2 no hydrogen 3.471 N/A ARG 123.A NH2 ASP 300.A O no hydrogen 2.881 N/A ARG 123.A NH2 ASP 300.A OD1 no hydrogen 2.920 N/A GLY 124.A N GLN 120.A O no hydrogen 3.096 N/A LEU 125.A N ILE 121.A O no hydrogen 2.833 N/A LYS 126.A N LEU 122.A O no hydrogen 2.776 N/A LYS 126.A NZ GLU 301.A O no hydrogen 2.749 N/A TYR 127.A N ARG 123.A O no hydrogen 3.346 N/A TYR 127.A OH HIS 68.A O no hydrogen 3.271 N/A ILE 128.A N GLY 124.A O no hydrogen 3.032 N/A HIS 129.A N LEU 125.A O no hydrogen 2.755 N/A HIS 129.A NE2 ASP 189.A OD2 no hydrogen 2.810 N/A SER 130.A N LYS 126.A O no hydrogen 2.995 N/A SER 130.A OG LYS 126.A O no hydrogen 2.977 N/A SER 130.A OG TYR 127.A O no hydrogen 2.515 N/A ALA 131.A N ILE 128.A O no hydrogen 3.252 N/A ASP 132.A N HIS 129.A O no hydrogen 2.845 N/A ILE 133.A N ILE 128.A O no hydrogen 3.124 N/A HIS 135.A N ASP 189.A OD2 no hydrogen 2.869 N/A HIS 135.A NE2 LEU 154.A O no hydrogen 2.750 N/A ARG 136.A N ASP 189.A OD1 no hydrogen 2.924 N/A ARG 136.A NE TYR 184.A OH no hydrogen 2.738 N/A ASP 137.A N HIS 135.A ND1 no hydrogen 3.311 N/A ASN 142.A N LYS 139.A O no hydrogen 3.062 N/A ASN 142.A ND2 ASP 137.A O no hydrogen 2.520 N/A LEU 143.A N PRO 140.A O no hydrogen 3.266 N/A ALA 144.A N LYS 152.A O no hydrogen 3.034 N/A VAL 145.A N ALA 102.A O no hydrogen 2.866 N/A ASN 146.A N GLU 150.A O no hydrogen 3.329 N/A ASN 146.A ND2 GLU 150.A OE1 no hydrogen 3.152 N/A CYS 149.A N ASN 146.A O no hydrogen 3.049 N/A GLU 150.A N ASN 146.A OD1 no hydrogen 3.366 N/A LEU 151.A N GLN 120.A OE1 no hydrogen 2.879 N/A LYS 152.A N ALA 144.A O no hydrogen 2.848 N/A LYS 152.A NZ GLU 72.A O no hydrogen 2.897 N/A ILE 153.A N ASN 73.A O no hydrogen 2.841 N/A LEU 154.A N ASN 142.A O no hydrogen 2.821 N/A HIS 158.A ND1 GLU 162.A OE1 no hydrogen 2.691 N/A HIS 158.A NE2 ASP 137.A OD2 no hydrogen 3.300 N/A GLU 162.A N THR 159.A OG1 no hydrogen 3.109 N/A MET 163.A N ASP 160.A O no hydrogen 3.227 N/A THR 164.A N ASP 161.A O no hydrogen 3.190 N/A THR 164.A OG1 ASP 160.A O no hydrogen 2.678 N/A THR 169.A OG1 GLU 162.A O no hydrogen 2.755 N/A ARG 170.A N VAL 167.A O no hydrogen 3.207 N/A ARG 170.A NE GLN 215.A OE1 no hydrogen 2.853 N/A ARG 170.A NH1 MET 163.A O no hydrogen 2.870 N/A ARG 170.A NH1 GLY 165.A O no hydrogen 2.760 N/A ARG 170.A NH2 GLY 165.A O no hydrogen 3.019 N/A ARG 170.A NH2 GLN 215.A OE1 no hydrogen 3.247 N/A TRP 171.A NE1 GLY 209.A O no hydrogen 3.010 N/A TYR 172.A OH GLU 199.A OE1 no hydrogen 2.416 N/A TYR 172.A OH GLU 199.A OE2 no hydrogen 3.323 N/A ARG 173.A N ARG 170.A O no hydrogen 3.095 N/A ARG 173.A NH2 ARG 136.A O no hydrogen 2.770 N/A GLU 176.A N GLU 176.A OE1 no hydrogen 3.012 N/A ILE 177.A N ALA 174.A O no hydrogen 3.051 N/A MET 178.A N ALA 174.A O no hydrogen 2.982 N/A LEU 179.A N PRO 175.A O no hydrogen 3.021 N/A ASN 180.A N ILE 177.A O no hydrogen 3.280 N/A TRP 181.A N GLU 176.A O no hydrogen 2.838 N/A GLN 186.A NE2 HIS 129.A O no hydrogen 2.908 N/A THR 187.A N ASN 185.A OD1 no hydrogen 2.921 N/A THR 187.A OG1 ASN 185.A OD1 no hydrogen 2.490 N/A VAL 188.A N ASN 185.A O no hydrogen 3.105 N/A ASP 189.A N GLN 186.A O no hydrogen 2.952 N/A TRP 191.A N THR 187.A O no hydrogen 3.222 N/A SER 192.A N VAL 188.A O no hydrogen 3.362 N/A SER 192.A OG TYR 172.A O no hydrogen 2.837 N/A SER 192.A OG VAL 188.A O no hydrogen 3.171 N/A VAL 193.A N ASP 189.A O no hydrogen 3.064 N/A GLY 194.A N ILE 190.A O no hydrogen 3.017 N/A CYS 195.A N TRP 191.A O no hydrogen 3.073 N/A CYS 195.A SG TRP 171.A O no hydrogen 3.968 N/A CYS 195.A SG TRP 191.A O no hydrogen 3.549 N/A ILE 196.A N SER 192.A O no hydrogen 2.860 N/A MET 197.A N VAL 193.A O no hydrogen 2.764 N/A ALA 198.A N GLY 194.A O no hydrogen 3.050 N/A GLU 199.A N CYS 195.A O no hydrogen 3.054 N/A LEU 200.A N ILE 196.A O no hydrogen 2.901 N/A LEU 201.A N MET 197.A O no hydrogen 3.131 N/A THR 202.A N ALA 198.A O no hydrogen 2.949 N/A THR 202.A OG1 ALA 198.A O no hydrogen 3.309 N/A GLY 203.A N GLU 199.A O no hydrogen 2.837 N/A ARG 204.A N THR 202.A OG1 no hydrogen 3.084 N/A GLY 209.A N PHE 207.A O no hydrogen 2.763 N/A THR 210.A N ASP 214.A OD2 no hydrogen 2.997 N/A THR 210.A OG1 ASP 211.A OD1 no hydrogen 3.266 N/A ILE 213.A N ASP 211.A OD2 no hydrogen 2.892 N/A ASP 214.A N ASP 211.A OD2 no hydrogen 3.008 N/A GLN 215.A N ASP 211.A O no hydrogen 3.033 N/A GLN 215.A NE2 ARG 170.A O no hydrogen 2.937 N/A LEU 216.A N HIS 212.A O no hydrogen 3.034 N/A LYS 217.A N ILE 213.A O no hydrogen 2.886 N/A LEU 218.A N ASP 214.A O no hydrogen 2.807 N/A ILE 219.A N GLN 215.A O no hydrogen 2.823 N/A LEU 220.A N LEU 216.A O no hydrogen 2.815 N/A ARG 221.A N LYS 217.A O no hydrogen 3.017 N/A LEU 222.A N LEU 218.A O no hydrogen 3.421 N/A VAL 223.A N ILE 219.A O no hydrogen 3.057 N/A GLY 224.A N LEU 220.A O no hydrogen 3.024 N/A THR 225.A N MET 249.A O no hydrogen 2.895 N/A THR 225.A OG1 MET 249.A O no hydrogen 3.064 N/A LEU 231.A N GLY 227.A O no hydrogen 3.068 N/A LYS 232.A N ALA 228.A O no hydrogen 3.194 N/A LYS 233.A N LEU 230.A O no hydrogen 2.986 N/A LYS 233.A NZ ASP 276.A OD1 no hydrogen 3.025 N/A LYS 233.A NZ ASP 276.A OD2 no hydrogen 3.002 N/A LYS 233.A NZ ASP 278.A OD2 no hydrogen 2.534 N/A ILE 234.A N LEU 231.A O no hydrogen 3.140 N/A SER 236.A N TRP 181.A O no hydrogen 3.163 N/A ALA 239.A N SER 236.A OG no hydrogen 3.166 N/A ARG 240.A N SER 236.A O no hydrogen 2.954 N/A ASN 241.A N GLU 237.A O no hydrogen 2.858 N/A TYR 242.A N SER 238.A O no hydrogen 3.064 N/A ILE 243.A N ALA 239.A O no hydrogen 2.968 N/A GLN 244.A N ARG 240.A O no hydrogen 3.171 N/A SER 245.A N TYR 242.A O no hydrogen 2.899 N/A SER 245.A OG TYR 242.A O no hydrogen 2.505 N/A LEU 246.A N ILE 243.A O no hydrogen 3.095 N/A MET 249.A N THR 225.A OG1 no hydrogen 2.804 N/A LYS 251.A NZ MET 252.A O no hydrogen 2.973 N/A LYS 251.A NZ GLU 270.A OE2 no hydrogen 2.752 N/A MET 252.A N LEU 222.A O no hydrogen 2.908 N/A ASN 256.A N ASN 253.A OD1 no hydrogen 3.143 N/A VAL 257.A N PHE 254.A O no hydrogen 3.086 N/A PHE 258.A N PHE 254.A O no hydrogen 2.783 N/A ALA 261.A N PHE 258.A O no hydrogen 3.169 N/A ASN 262.A ND2 ASP 111.A OD2 no hydrogen 2.771 N/A LEU 264.A N ASN 262.A OD1 no hydrogen 2.946 N/A VAL 266.A N ASN 262.A O no hydrogen 3.073 N/A ASP 267.A N PRO 263.A O no hydrogen 2.850 N/A LEU 268.A N LEU 264.A O no hydrogen 2.955 N/A LEU 269.A N ALA 265.A O no hydrogen 2.976 N/A GLU 270.A N VAL 266.A O no hydrogen 3.040 N/A LYS 271.A N ASP 267.A O no hydrogen 3.367 N/A LYS 271.A N LEU 268.A O no hydrogen 3.007 N/A LYS 271.A NZ ASP 267.A OD2 no hydrogen 2.981 N/A MET 272.A N LEU 268.A O no hydrogen 3.013 N/A MET 272.A N LEU 269.A O no hydrogen 3.190 N/A LEU 273.A N LEU 269.A O no hydrogen 2.869 N/A ASP 278.A N ASP 276.A OD1 no hydrogen 3.326 N/A LYS 279.A N ASP 276.A O no hydrogen 2.919 N/A LYS 279.A NZ GLU 229.A OE1 no hydrogen 2.588 N/A LYS 279.A NZ ASP 276.A OD2 no hydrogen 3.455 N/A ARG 280.A N SER 277.A O no hydrogen 3.465 N/A ARG 280.A NE VAL 274.A O no hydrogen 2.989 N/A ARG 280.A NH1 GLU 176.A OE2 no hydrogen 2.811 N/A ARG 280.A NH1 THR 187.A O no hydrogen 3.407 N/A ARG 280.A NH2 GLU 176.A OE1 no hydrogen 2.924 N/A ARG 280.A NH2 VAL 274.A O no hydrogen 3.447 N/A ARG 280.A NH2 LEU 275.A O no hydrogen 3.023 N/A ILE 281.A N LYS 271.A O no hydrogen 3.041 N/A THR 282.A N GLN 285.A OE1 no hydrogen 2.928 N/A GLN 285.A N THR 282.A OG1 no hydrogen 2.939 N/A ALA 286.A N THR 282.A O no hydrogen 2.675 N/A LEU 287.A N ALA 283.A O no hydrogen 3.157 N/A ALA 288.A N GLN 285.A O no hydrogen 3.161 N/A HIS 289.A N ALA 286.A O no hydrogen 2.967 N/A HIS 289.A NE2 ASP 267.A OD2 no hydrogen 2.694 N/A TYR 291.A N HIS 289.A ND1 no hydrogen 3.330 N/A TYR 291.A OH ASP 111.A OD1 no hydrogen 2.542 N/A PHE 292.A N HIS 289.A O no hydrogen 3.037 N/A ALA 293.A N ALA 290.A O no hydrogen 2.904 N/A TYR 295.A N PHE 292.A O no hydrogen 3.008 N/A HIS 296.A N PHE 292.A O no hydrogen 2.790 N/A HIS 296.A ND1 GLU 301.A OE2 no hydrogen 3.092 N/A ASP 297.A N GLU 301.A OE2 no hydrogen 3.048 N/A ASP 299.A N ASP 297.A OD1 no hydrogen 2.961 N/A ASP 300.A N ASP 297.A O no hydrogen 2.983 N/A ALA 304.A N SER 130.A OG no hydrogen 3.140 N/A GLN 309.A NE2 ASP 132.A O no hydrogen 2.862 N/A SER 310.A N ASP 308.A OD1 no hydrogen 2.845 N/A SER 310.A OG ASP 308.A OD1 no hydrogen 2.581 N/A GLU 312.A N GLN 309.A O no hydrogen 2.940 N/A SER 313.A N SER 310.A O no hydrogen 3.181 N/A SER 313.A OG SER 310.A O no hydrogen 2.937 N/A ARG 314.A N PHE 311.A O no hydrogen 3.019 N/A LEU 317.A N GLU 320.A OE1 no hydrogen 2.872 N/A TRP 321.A N LEU 317.A O no hydrogen 3.191 N/A LYS 322.A N ILE 318.A O no hydrogen 2.948 N/A LYS 322.A NZ PHE 90.A O no hydrogen 2.618 N/A SER 323.A N ASP 319.A O no hydrogen 2.914 N/A LEU 324.A N GLU 320.A O no hydrogen 2.997 N/A THR 325.A N TRP 321.A O no hydrogen 2.931 N/A THR 325.A OG1 TRP 321.A O no hydrogen 2.707 N/A TYR 326.A N LYS 322.A O no hydrogen 2.771 N/A ASP 327.A N SER 323.A O no hydrogen 3.054 N/A GLU 328.A N LEU 324.A O no hydrogen 3.407 N/A VAL 329.A N THR 325.A O no hydrogen 3.116 N/A VAL 329.A N TYR 326.A O no hydrogen 2.905 N/A ILE 330.A N TYR 326.A O no hydrogen 3.060 N/A SER 331.A N ASP 327.A O no hydrogen 3.027 N/A SER 331.A OG ASP 327.A O no hydrogen 2.683 N/A PHE 332.A N VAL 329.A O no hydrogen 3.136 N/A