Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5yia_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A ND2 GLU 173.A OE2 no hydrogen 3.266 N/A ASP 3.A N ILE 169.A O no hydrogen 3.165 N/A ASN 4.A ND2 ASN 2.A O no hydrogen 3.418 N/A ASN 4.A ND2 GLU 173.A OE2 no hydrogen 3.379 N/A ILE 5.A N LEU 167.A O no hydrogen 2.834 N/A LEU 7.A N GLY 165.A O no hydrogen 2.828 N/A VAL 8.A N TYR 16.A O no hydrogen 2.875 N/A PHE 10.A N MET 14.A O no hydrogen 2.900 N/A ASN 12.A N ASP 9.A OD2 no hydrogen 2.916 N/A MET 14.A N PHE 10.A O no hydrogen 3.485 N/A TYR 16.A N VAL 8.A O no hydrogen 2.869 N/A GLY 17.A N PHE 30.A O no hydrogen 3.079 N/A ALA 19.A N PHE 28.A O no hydrogen 3.118 N/A GLU 20.A N THR 91.A O no hydrogen 2.969 N/A VAL 21.A N GLN 26.A O no hydrogen 3.110 N/A GLY 22.A N LEU 89.A O no hydrogen 2.866 N/A ASP 23.A N SER 62.A OG no hydrogen 3.105 N/A GLN 25.A N GLY 22.A O no hydrogen 2.981 N/A GLN 26.A N VAL 21.A O no hydrogen 3.114 N/A GLN 26.A NE2 ASN 24.A OD1 no hydrogen 2.819 N/A GLN 26.A NE2 ASP 58.A O no hydrogen 2.929 N/A PHE 28.A N ALA 19.A O no hydrogen 3.035 N/A THR 29.A N ASP 120.A OD2 no hydrogen 2.742 N/A THR 29.A OG1 ASP 18.A OD1 no hydrogen 2.800 N/A PHE 30.A N GLY 17.A O no hydrogen 2.768 N/A ILE 31.A N GLY 121.A O no hydrogen 3.052 N/A ASP 33.A N LEU 123.A O no hydrogen 2.909 N/A THR 34.A N SER 214.A OG no hydrogen 2.858 N/A THR 34.A OG1 VAL 212.A O no hydrogen 3.279 N/A GLY 35.A N ASP 33.A OD1 no hydrogen 3.080 N/A SER 36.A N ASP 33.A O no hydrogen 3.404 N/A SER 36.A OG ASP 33.A OD2 no hydrogen 2.677 N/A ASN 38.A ND2 ILE 132.A O no hydrogen 2.901 N/A TRP 40.A N ILE 122.A O no hydrogen 2.960 N/A VAL 41.A N ILE 102.A O no hydrogen 3.075 N/A SER 43.A N VAL 104.A O no hydrogen 2.805 N/A SER 43.A OG GLU 103.A OE2 no hydrogen 2.649 N/A VAL 44.A N TYR 57.A O no hydrogen 2.913 N/A LYS 45.A N SER 43.A OG no hydrogen 2.968 N/A CYS 46.A N SER 43.A O no hydrogen 2.904 N/A CYS 46.A SG THR 48.A O no hydrogen 4.022 N/A CYS 46.A SG THR 48.A OG1 no hydrogen 3.191 N/A CYS 46.A SG ILE 105.A O no hydrogen 3.432 N/A THR 47.A N ILE 105.A O no hydrogen 2.995 N/A THR 47.A OG1 ILE 105.A O no hydrogen 3.465 N/A THR 48.A OG1 THR 107.A OG1 no hydrogen 2.895 N/A CYS 51.A N THR 48.A O no hydrogen 3.111 N/A LEU 52.A N ALA 49.A O no hydrogen 3.013 N/A LYS 54.A N CYS 51.A O no hydrogen 3.024 N/A LYS 54.A NZ TYR 114.A O no hydrogen 2.938 N/A LYS 54.A NZ PHE 119.A O no hydrogen 2.797 N/A HIS 55.A N ASP 120.A OD1 no hydrogen 3.033 N/A TYR 57.A N PRO 42.A O no hydrogen 2.787 N/A TYR 57.A OH ASP 88.A OD2 no hydrogen 2.505 N/A ASP 58.A N GLN 26.A OE1 no hydrogen 2.771 N/A SER 60.A N ASP 58.A OD1 no hydrogen 3.141 N/A SER 60.A OG ASP 58.A OD1 no hydrogen 2.692 N/A LYS 61.A N ASP 58.A O no hydrogen 3.125 N/A SER 62.A N SER 59.A O no hydrogen 3.183 N/A SER 62.A OG ASP 23.A OD1 no hydrogen 3.518 N/A SER 62.A OG ASP 88.A OD1 no hydrogen 2.942 N/A SER 62.A OG ASP 88.A OD2 no hydrogen 2.760 N/A ARG 63.A N ASP 23.A OD1 no hydrogen 2.909 N/A THR 64.A OG1 SER 62.A OG no hydrogen 3.133 N/A THR 64.A OG1 ASP 88.A OD1 no hydrogen 2.626 N/A TYR 65.A N SER 62.A O no hydrogen 3.285 N/A GLU 66.A N LYS 87.A O no hydrogen 2.688 N/A GLY 69.A N PHE 85.A O no hydrogen 2.857 N/A THR 70.A N ASP 68.A OD1 no hydrogen 2.984 N/A THR 70.A OG1 ASP 68.A OD1 no hydrogen 2.630 N/A VAL 72.A N GLY 83.A O no hydrogen 2.955 N/A MET 74.A N VAL 81.A O no hydrogen 2.756 N/A ASN 75.A ND2 GLU 73.A OE2 no hydrogen 3.332 N/A TYR 76.A N GLY 79.A O no hydrogen 2.708 N/A GLY 79.A N TYR 76.A O no hydrogen 3.140 N/A THR 80.A N GLY 109.A O no hydrogen 2.916 N/A THR 80.A OG1 ASN 75.A OD1 no hydrogen 2.801 N/A VAL 81.A N MET 74.A O no hydrogen 3.088 N/A SER 82.A N ASP 106.A O no hydrogen 3.079 N/A GLY 83.A N VAL 72.A O no hydrogen 2.894 N/A PHE 84.A N GLU 103.A O no hydrogen 2.992 N/A PHE 85.A N THR 70.A O no hydrogen 2.915 N/A SER 86.A N PHE 101.A O no hydrogen 2.818 N/A SER 86.A OG GLU 103.A OE1 no hydrogen 2.636 N/A LYS 87.A N GLU 66.A O no hydrogen 3.008 N/A ASP 88.A N TYR 99.A O no hydrogen 3.109 N/A LEU 89.A N ASP 88.A OD1 no hydrogen 2.819 N/A VAL 90.A N LEU 97.A O no hydrogen 2.856 N/A THR 91.A N GLU 20.A O no hydrogen 2.879 N/A THR 91.A OG1 SER 96.A OG no hydrogen 2.954 N/A VAL 92.A N LEU 95.A O no hydrogen 2.751 N/A ASN 94.A N ASP 3.A OD2 no hydrogen 2.887 N/A LEU 95.A N VAL 92.A O no hydrogen 2.832 N/A SER 96.A OG THR 91.A OG1 no hydrogen 2.954 N/A LEU 97.A N VAL 90.A O no hydrogen 3.021 N/A TYR 99.A N ASP 88.A O no hydrogen 2.788 N/A TYR 99.A OH ASP 136.A O no hydrogen 2.679 N/A LYS 100.A NZ GLY 133.A O no hydrogen 3.174 N/A PHE 101.A N SER 86.A O no hydrogen 2.951 N/A ILE 102.A N LEU 39.A O no hydrogen 2.939 N/A GLU 103.A N PHE 84.A O no hydrogen 2.706 N/A VAL 104.A N VAL 41.A O no hydrogen 2.859 N/A ILE 105.A N SER 82.A O no hydrogen 2.846 N/A ASP 106.A N SER 82.A O no hydrogen 3.179 N/A THR 107.A N THR 48.A OG1 no hydrogen 3.145 N/A THR 107.A OG1 THR 48.A OG1 no hydrogen 2.895 N/A ASN 108.A N ASP 106.A OD1 no hydrogen 2.939 N/A PHE 110.A N THR 107.A O no hydrogen 2.959 N/A TYR 114.A N PHE 110.A O no hydrogen 2.898 N/A TYR 114.A OH ASP 120.A O no hydrogen 2.592 N/A THR 115.A N GLU 111.A OE1 no hydrogen 2.986 N/A THR 115.A OG1 GLU 111.A OE1 no hydrogen 3.092 N/A THR 115.A OG1 GLU 111.A OE2 no hydrogen 2.591 N/A ALA 116.A N PRO 112.A O no hydrogen 3.133 N/A SER 117.A N TYR 114.A O no hydrogen 3.472 N/A SER 117.A OG THR 113.A O no hydrogen 2.713 N/A ASP 120.A N THR 29.A O no hydrogen 2.760 N/A GLY 121.A N THR 29.A O no hydrogen 3.119 N/A LEU 123.A N ILE 31.A O no hydrogen 2.867 N/A GLY 124.A N ASN 38.A O no hydrogen 3.080 N/A LEU 125.A N ASP 33.A O no hydrogen 2.779 N/A LYS 128.A NZ ASP 136.A OD2 no hydrogen 3.414 N/A LEU 130.A N TRP 127.A O no hydrogen 3.006 N/A SER 131.A N LYS 128.A O no hydrogen 2.818 N/A SER 131.A OG LYS 128.A O no hydrogen 2.664 N/A SER 131.A OG VAL 135.A O no hydrogen 3.549 N/A ILE 132.A N ASN 38.A OD1 no hydrogen 2.788 N/A VAL 135.A N SER 131.A OG no hydrogen 2.971 N/A GLU 141.A N PRO 137.A O no hydrogen 2.870 N/A LEU 142.A N ILE 138.A O no hydrogen 2.807 N/A LYS 143.A N VAL 139.A O no hydrogen 2.986 N/A ASN 144.A N VAL 140.A O no hydrogen 2.910 N/A GLN 145.A N GLU 141.A O no hydrogen 3.034 N/A ASN 146.A N LYS 143.A O no hydrogen 2.812 N/A LYS 147.A N LEU 142.A O no hydrogen 2.884 N/A LYS 147.A NZ SER 96.A O no hydrogen 2.724 N/A LYS 147.A NZ GLN 145.A OE1 no hydrogen 2.686 N/A ASN 150.A N GLY 170.A O no hydrogen 3.045 N/A ASN 150.A ND2 GLY 170.A O no hydrogen 3.061 N/A ALA 151.A N ASP 315.A OD2 no hydrogen 3.172 N/A PHE 153.A N PHE 312.A O no hydrogen 3.033 N/A THR 154.A N THR 168.A O no hydrogen 2.840 N/A PHE 155.A N THR 310.A O no hydrogen 2.846 N/A TYR 156.A N PHE 166.A O no hydrogen 2.926 N/A TYR 156.A OH LYS 325.A O no hydrogen 2.857 N/A VAL 159.A N HIS 163.A O no hydrogen 3.022 N/A LYS 162.A N VAL 159.A O no hydrogen 2.879 N/A HIS 163.A N VAL 159.A O no hydrogen 3.089 N/A HIS 163.A ND1 THR 164.A O no hydrogen 2.771 N/A THR 164.A OG1 GLU 6.A OE2 no hydrogen 3.084 N/A THR 164.A OG1 LEU 7.A O no hydrogen 3.342 N/A GLY 165.A N LEU 7.A O no hydrogen 3.083 N/A PHE 166.A N TYR 156.A O no hydrogen 2.782 N/A LEU 167.A N ILE 5.A O no hydrogen 2.844 N/A THR 168.A N THR 154.A O no hydrogen 2.969 N/A THR 168.A OG1 ASN 4.A OD1 no hydrogen 2.704 N/A ILE 169.A N ASP 3.A O no hydrogen 2.746 N/A GLY 170.A N LEU 152.A O no hydrogen 2.908 N/A ARG 175.A NE GLU 173.A OE1 no hydrogen 2.983 N/A ARG 175.A NH1 ASN 4.A OD1 no hydrogen 3.492 N/A ARG 175.A NH1 GLU 173.A OE1 no hydrogen 3.405 N/A PHE 176.A N GLU 173.A O no hydrogen 3.170 N/A TYR 177.A N GLU 174.A O no hydrogen 3.387 N/A TYR 177.A OH GLU 174.A OE2 no hydrogen 2.532 N/A GLU 178.A N LEU 323.A O no hydrogen 2.908 N/A THR 182.A N ILE 321.A O no hydrogen 2.997 N/A TYR 183.A OH.A ASP 313.A OD2 no hydrogen 2.760 N/A GLU 184.A N VAL 319.A O no hydrogen 2.740 N/A LYS 185.A NZ ASN 316.A O no hydrogen 2.967 N/A LEU 186.A N GLN 317.A O no hydrogen 2.921 N/A ASN 187.A N GLN 193.A O no hydrogen 2.874 N/A ASN 187.A ND2 THR 195.A OG1 no hydrogen 2.670 N/A ASN 187.A ND2 ASN 209.A OD1 no hydrogen 3.024 N/A LEU 190.A N HIS 188.A ND1 no hydrogen 3.285 N/A TRP 192.A NE1 LEU 125.A O no hydrogen 2.919 N/A GLN 193.A NE2 ASN 187.A OD1 no hydrogen 2.809 N/A ILE 194.A N CYS 210.A O no hydrogen 2.797 N/A LEU 196.A N ALA 208.A O no hydrogen 3.077 N/A ASP 197.A N THR 259.A O no hydrogen 2.841 N/A ALA 198.A N LEU 205.A O no hydrogen 2.873 N/A HIS 199.A N GLU 257.A O no hydrogen 2.747 N/A VAL 200.A N ILE 203.A O no hydrogen 2.842 N/A ILE 203.A N VAL 200.A O no hydrogen 3.076 N/A LEU 205.A N ALA 198.A O no hydrogen 2.814 N/A LYS 207.A N ASP 197.A OD1 no hydrogen 2.645 N/A ALA 208.A N LEU 196.A O no hydrogen 2.731 N/A ASN 209.A N PRO 296.A O no hydrogen 3.280 N/A CYS 210.A N ILE 194.A O no hydrogen 2.800 N/A CYS 210.A SG ALA 208.A O no hydrogen 4.049 N/A ILE 211.A N PHE 298.A O no hydrogen 2.920 N/A VAL 212.A N TRP 192.A O no hydrogen 2.988 N/A ASP 213.A N LEU 300.A O no hydrogen 3.105 N/A SER 214.A N THR 34.A OG1 no hydrogen 2.959 N/A SER 214.A OG LEU 32.A O no hydrogen 2.542 N/A GLY 215.A N ASP 213.A OD2 no hydrogen 2.902 N/A THR 216.A N ASP 213.A O no hydrogen 3.519 N/A THR 216.A OG1 ASP 213.A OD2 no hydrogen 2.896 N/A SER 217.A OG.B ILE 13.A O no hydrogen 2.939 N/A ILE 219.A N ASN 287.A O no hydrogen 2.888 N/A THR 220.A N ILE 299.A O no hydrogen 3.055 N/A VAL 221.A N ILE 289.A O no hydrogen 2.967 N/A THR 223.A N ASP 292.A OD1 no hydrogen 2.944 N/A THR 223.A OG1 ASP 292.A OD1 no hydrogen 3.264 N/A THR 223.A OG1 ASP 292.A OD2 no hydrogen 2.549 N/A LEU 226.A N PRO 222.A O no hydrogen 2.868 N/A ASN 227.A N THR 223.A O no hydrogen 2.855 N/A LYS 228.A N ASP 224.A O no hydrogen 3.084 N/A LYS 228.A NZ ASP 224.A OD2 no hydrogen 3.015 N/A MET 229.A N PHE 225.A O no hydrogen 2.986 N/A LEU 230.A N LEU 226.A O no hydrogen 2.941 N/A GLN 231.A N LYS 228.A O no hydrogen 3.409 N/A LEU 233.A N LEU 230.A O no hydrogen 3.220 N/A ILE 236.A N VAL 245.A O no hydrogen 2.893 N/A LYS 237.A NZ VAL 238.A O no hydrogen 3.007 N/A LYS 237.A NZ LEU 241.A O no hydrogen 2.771 N/A VAL 238.A N PHE 243.A O no hydrogen 2.752 N/A LEU 241.A N VAL 238.A O no hydrogen 3.258 N/A VAL 245.A N ILE 236.A O no hydrogen 2.765 N/A THR 246.A N CYS 284.A O no hydrogen 2.850 N/A THR 246.A OG1 LEU 247.A O no hydrogen 3.012 N/A CYS 248.A N GLY 282.A O no hydrogen 2.907 N/A CYS 248.A SG HIS 275.A ND1 no hydrogen 3.705 N/A ASN 250.A N LEU 247.A O no hydrogen 3.148 N/A ASN 250.A ND2 LEU 233.A O no hydrogen 2.801 N/A ASN 250.A ND2 THR 246.A OG1 no hydrogen 3.004 N/A LYS 252.A N ASN 250.A OD1 no hydrogen 3.086 N/A LYS 252.A NZ ASN 232.A O no hydrogen 2.824 N/A LYS 252.A NZ ASP 234.A OD2 no hydrogen 2.970 N/A LEU 253.A N ASN 250.A O no hydrogen 3.150 N/A PHE 256.A N LEU 267.A O no hydrogen 2.941 N/A GLU 257.A N HIS 199.A O no hydrogen 2.819 N/A PHE 258.A N TYR 265.A O no hydrogen 2.804 N/A THR 259.A N ASP 197.A O no hydrogen 2.876 N/A SER 260.A N GLY 263.A O no hydrogen 2.943 N/A SER 260.A OG GLU 184.A OE1 no hydrogen 3.217 N/A SER 260.A OG GLU 184.A OE2 no hydrogen 2.633 N/A SER 260.A OG GLY 263.A O no hydrogen 3.550 N/A ASN 262.A N SER 260.A OG no hydrogen 2.928 N/A GLY 263.A N SER 260.A OG no hydrogen 2.864 N/A TYR 265.A N PHE 258.A O no hydrogen 2.834 N/A TYR 265.A OH GLU 184.A OE2 no hydrogen 2.579 N/A THR 266.A N TYR 308.A OH no hydrogen 2.856 N/A THR 266.A OG1 GLU 268.A OE1 no hydrogen 2.663 N/A LEU 267.A N PHE 256.A O no hydrogen 2.775 N/A TYR 271.A N GLU 268.A O no hydrogen 2.933 N/A TYR 272.A N PRO 269.A O no hydrogen 2.912 N/A TYR 272.A OH PRO 254.A O no hydrogen 2.588 N/A LEU 273.A N PRO 269.A O no hydrogen 2.917 N/A GLN 274.A N MET 285.A O no hydrogen 2.848 N/A GLN 274.A NE2 ASN 12.A O no hydrogen 3.309 N/A ILE 276.A N LEU 283.A O no hydrogen 2.975 N/A VAL 279.A N ILE 276.A O no hydrogen 2.874 N/A GLY 280.A N ILE 276.A O no hydrogen 3.072 N/A GLY 282.A N GLU 277.A OE1 no hydrogen 2.882 N/A LEU 283.A N GLY 280.A O no hydrogen 3.445 N/A CYS 284.A N THR 246.A O no hydrogen 2.782 N/A MET 285.A N GLN 274.A O no hydrogen 2.782 N/A LEU 286.A N TYR 244.A O no hydrogen 2.946 N/A ASN 287.A N TYR 272.A O no hydrogen 2.747 N/A ASN 287.A ND2 GLN 274.A OE1 no hydrogen 3.002 N/A ILE 289.A N ILE 219.A O no hydrogen 2.903 N/A LEU 291.A N VAL 221.A O no hydrogen 2.836 N/A THR 297.A OG1 VAL 295.A O no hydrogen 2.582 N/A PHE 298.A N ASN 209.A O no hydrogen 2.884 N/A ILE 299.A N THR 220.A O no hydrogen 3.104 N/A ILE 299.A N THR 220.A OG1 no hydrogen 3.029 N/A LEU 300.A N ILE 211.A O no hydrogen 2.689 N/A ASP 302.A N THR 216.A O no hydrogen 2.727 N/A MET 305.A N GLY 301.A O no hydrogen 3.134 N/A ARG 306.A N ASP 302.A O no hydrogen 2.874 N/A ARG 306.A NE ASP 302.A OD2.A no hydrogen 2.756 N/A ARG 306.A NE ASP 302.A OD2.B no hydrogen 2.725 N/A ARG 306.A NH1 ASP 9.A OD1 no hydrogen 2.962 N/A ARG 306.A NH2 ASP 9.A OD1 no hydrogen 3.128 N/A ARG 306.A NH2 MET 14.A O no hydrogen 3.328 N/A ARG 306.A NH2 ASP 302.A OD1.B no hydrogen 3.138 N/A ARG 306.A NH2 ASP 302.A OD2.A no hydrogen 2.865 N/A ARG 306.A NH2 ASP 302.A OD2.B no hydrogen 3.422 N/A LYS 307.A N PHE 304.A O no hydrogen 3.180 N/A LYS 307.A NZ THR 266.A O no hydrogen 2.737 N/A LYS 307.A NZ GLU 268.A OE1 no hydrogen 3.354 N/A LYS 307.A NZ GLU 268.A OE2 no hydrogen 2.824 N/A LYS 307.A NZ TYR 308.A OH no hydrogen 3.270 N/A TYR 308.A N PHE 304.A O no hydrogen 2.989 N/A TYR 308.A OH THR 266.A O no hydrogen 3.361 N/A THR 310.A N PHE 155.A O no hydrogen 3.221 N/A VAL 311.A N GLY 320.A O no hydrogen 2.854 N/A PHE 312.A N PHE 153.A O no hydrogen 2.731 N/A ASP 313.A N SER 318.A O no hydrogen 3.023 N/A TYR 314.A N ALA 151.A O no hydrogen 2.970 N/A TYR 314.A OH GLY 126.A O no hydrogen 2.704 N/A ASN 316.A N ASP 313.A OD1 no hydrogen 2.974 N/A ASN 316.A ND2 ASP 313.A OD2 no hydrogen 2.746 N/A GLN 317.A N TYR 314.A O no hydrogen 3.367 N/A SER 318.A N ASP 313.A O no hydrogen 3.195 N/A SER 318.A OG.B ASN 316.A O no hydrogen 2.814 N/A VAL 319.A N GLU 184.A O no hydrogen 2.912 N/A GLY 320.A N VAL 311.A O no hydrogen 2.817 N/A ILE 321.A N THR 182.A O no hydrogen 2.795 N/A ALA 322.A N PHE 309.A O no hydrogen 2.950 N/A ALA 324.A N LYS 307.A O no hydrogen 2.997 N/A LYS 325.A N PHE 176.A O no hydrogen 3.041 N/A LYS 325.A NZ GLU 174.A O no hydrogen 3.354 N/A LYS 325.A NZ TYR 177.A O no hydrogen 3.111 N/A