Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5yie_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 1.A ND2 GLU 172.A OE2 no hydrogen 3.258 N/A ILE 4.A N LEU 166.A O no hydrogen 2.826 N/A LEU 6.A N GLY 164.A O no hydrogen 2.802 N/A VAL 7.A N TYR 15.A O no hydrogen 2.976 N/A PHE 9.A N MET 13.A O no hydrogen 2.900 N/A ASN 11.A N ASP 8.A OD2 no hydrogen 2.963 N/A ILE 12.A N PHE 9.A O no hydrogen 3.276 N/A MET 13.A N PHE 9.A O no hydrogen 3.306 N/A TYR 15.A N VAL 7.A O no hydrogen 2.914 N/A GLY 16.A N PHE 29.A O no hydrogen 3.019 N/A ALA 18.A N PHE 27.A O no hydrogen 3.038 N/A GLU 19.A N THR 90.A O no hydrogen 3.130 N/A VAL 20.A N GLN 25.A O no hydrogen 3.366 N/A GLY 21.A N LEU 88.A O no hydrogen 2.889 N/A ASP 22.A N SER 61.A OG no hydrogen 3.197 N/A GLN 24.A N GLY 21.A O no hydrogen 3.138 N/A GLN 24.A NE2 GLU 19.A OE1 no hydrogen 2.684 N/A GLN 25.A NE2 ASN 23.A OD1 no hydrogen 2.968 N/A GLN 25.A NE2 ASP 57.A O no hydrogen 3.105 N/A PHE 27.A N ALA 18.A O no hydrogen 2.898 N/A THR 28.A N ASP 119.A OD2 no hydrogen 2.845 N/A THR 28.A OG1 ASP 17.A OD1 no hydrogen 2.972 N/A PHE 29.A N GLY 16.A O no hydrogen 2.687 N/A ILE 30.A N GLY 120.A O no hydrogen 3.046 N/A ASP 32.A N LEU 122.A O no hydrogen 2.973 N/A THR 33.A N SER 213.A OG no hydrogen 2.864 N/A THR 33.A OG1 VAL 211.A O no hydrogen 3.370 N/A THR 33.A OG1 ASP 212.A OD1.A no hydrogen 3.309 N/A GLY 34.A N ASP 32.A OD1 no hydrogen 2.980 N/A SER 35.A N ASP 32.A O no hydrogen 3.332 N/A SER 35.A OG ASP 32.A OD2 no hydrogen 2.580 N/A ASN 37.A ND2 ILE 131.A O no hydrogen 2.940 N/A TRP 39.A N ILE 121.A O no hydrogen 2.979 N/A TRP 39.A NE1 TYR 75.A OH no hydrogen 2.919 N/A VAL 40.A N ILE 101.A O no hydrogen 3.087 N/A SER 42.A N VAL 103.A O no hydrogen 2.904 N/A SER 42.A OG TYR 56.A O no hydrogen 3.510 N/A SER 42.A OG GLU 102.A OE1 no hydrogen 2.549 N/A VAL 43.A N TYR 56.A O no hydrogen 3.037 N/A LYS 44.A N SER 42.A OG no hydrogen 3.050 N/A CYS 45.A N SER 42.A O no hydrogen 2.785 N/A CYS 45.A SG THR 47.A OG1 no hydrogen 3.144 N/A CYS 45.A SG ILE 104.A O no hydrogen 3.410 N/A THR 47.A OG1 THR 106.A OG1 no hydrogen 2.488 N/A CYS 50.A N THR 47.A O no hydrogen 3.060 N/A CYS 50.A SG THR 47.A OG1 no hydrogen 3.432 N/A LEU 51.A N ALA 48.A O no hydrogen 3.227 N/A THR 52.A OG1 GLY 49.A O no hydrogen 2.992 N/A LYS 53.A N CYS 50.A O no hydrogen 2.990 N/A LYS 53.A NZ TYR 113.A O no hydrogen 2.856 N/A LYS 53.A NZ PHE 118.A O no hydrogen 2.897 N/A HIS 54.A N ASP 119.A OD1 no hydrogen 3.047 N/A HIS 54.A ND1 ASP 119.A OD2 no hydrogen 2.810 N/A TYR 56.A N PRO 41.A O no hydrogen 2.774 N/A TYR 56.A OH ASP 87.A OD2 no hydrogen 2.463 N/A ASP 57.A N GLN 25.A OE1 no hydrogen 2.835 N/A SER 59.A N ASP 57.A OD1 no hydrogen 3.085 N/A SER 59.A OG ASP 57.A OD1 no hydrogen 2.574 N/A SER 59.A OG ASP 57.A OD2 no hydrogen 3.504 N/A LYS 60.A N ASP 57.A O no hydrogen 3.168 N/A SER 61.A N SER 58.A O no hydrogen 3.140 N/A SER 61.A OG ASP 87.A OD1 no hydrogen 3.046 N/A SER 61.A OG ASP 87.A OD2 no hydrogen 2.696 N/A ARG 62.A NE ASP 22.A OD2 no hydrogen 2.630 N/A ARG 62.A NH1 ASP 22.A OD2 no hydrogen 2.921 N/A THR 63.A OG1 SER 61.A OG no hydrogen 3.414 N/A THR 63.A OG1 ASP 87.A OD1 no hydrogen 2.594 N/A GLU 65.A N LYS 86.A O no hydrogen 2.765 N/A GLY 68.A N PHE 84.A O no hydrogen 2.854 N/A THR 69.A N ASP 67.A OD1 no hydrogen 3.091 N/A THR 69.A OG1 ASP 67.A OD1 no hydrogen 2.467 N/A VAL 71.A N GLY 82.A O no hydrogen 2.957 N/A MET 73.A N VAL 80.A O no hydrogen 2.778 N/A ASN 74.A ND2 GLU 72.A OE2 no hydrogen 3.332 N/A TYR 75.A N GLY 78.A O no hydrogen 2.791 N/A GLY 78.A N TYR 75.A O no hydrogen 3.185 N/A THR 79.A N GLY 108.A O no hydrogen 2.717 N/A THR 79.A OG1 ASN 74.A OD1 no hydrogen 2.754 N/A VAL 80.A N MET 73.A O no hydrogen 3.152 N/A SER 81.A N ASP 105.A O no hydrogen 3.141 N/A GLY 82.A N VAL 71.A O no hydrogen 2.937 N/A PHE 83.A N GLU 102.A O no hydrogen 3.100 N/A PHE 84.A N THR 69.A O no hydrogen 2.845 N/A SER 85.A N PHE 100.A O no hydrogen 2.887 N/A SER 85.A OG GLU 102.A OE2 no hydrogen 2.856 N/A LYS 86.A N GLU 65.A O no hydrogen 2.993 N/A ASP 87.A N TYR 98.A O no hydrogen 3.084 N/A LEU 88.A N ASP 87.A OD1 no hydrogen 2.789 N/A VAL 89.A N LEU 96.A O no hydrogen 2.945 N/A THR 90.A N GLU 19.A O no hydrogen 2.713 N/A VAL 91.A N LEU 94.A O no hydrogen 2.715 N/A ASN 93.A N ASP 2.A OD1 no hydrogen 2.729 N/A LEU 94.A N VAL 91.A O no hydrogen 2.921 N/A LEU 96.A N VAL 89.A O no hydrogen 3.117 N/A TYR 98.A N ASP 87.A O no hydrogen 2.870 N/A TYR 98.A OH ASP 135.A O no hydrogen 2.690 N/A LYS 99.A NZ GLY 132.A O no hydrogen 3.421 N/A PHE 100.A N SER 85.A O no hydrogen 2.998 N/A ILE 101.A N LEU 38.A O no hydrogen 2.932 N/A GLU 102.A N PHE 83.A O no hydrogen 2.751 N/A VAL 103.A N VAL 40.A O no hydrogen 2.845 N/A ILE 104.A N SER 81.A O no hydrogen 2.863 N/A ASP 105.A N SER 81.A O no hydrogen 3.170 N/A THR 106.A OG1 THR 47.A OG1 no hydrogen 2.488 N/A ASN 107.A N ASP 105.A OD1 no hydrogen 2.821 N/A PHE 109.A N THR 106.A O no hydrogen 2.923 N/A TYR 113.A N PHE 109.A O no hydrogen 2.921 N/A TYR 113.A OH ASP 119.A O no hydrogen 2.611 N/A THR 114.A N GLU 110.A OE1 no hydrogen 3.057 N/A THR 114.A OG1 GLU 110.A OE1 no hydrogen 3.223 N/A THR 114.A OG1 GLU 110.A OE2 no hydrogen 2.530 N/A ALA 115.A N PRO 111.A O no hydrogen 3.215 N/A SER 116.A N THR 112.A O no hydrogen 3.237 N/A SER 116.A N TYR 113.A O no hydrogen 3.454 N/A SER 116.A OG THR 112.A O no hydrogen 2.797 N/A ASP 119.A N THR 28.A O no hydrogen 2.798 N/A GLY 120.A N THR 28.A O no hydrogen 3.263 N/A LEU 122.A N ILE 30.A O no hydrogen 2.821 N/A GLY 123.A N ASN 37.A O no hydrogen 2.967 N/A LEU 124.A N ASP 32.A O no hydrogen 2.756 N/A GLY 125.A N SER 35.A O no hydrogen 2.879 N/A LYS 127.A NZ ASP 135.A OD1 no hydrogen 3.137 N/A LEU 129.A N TRP 126.A O no hydrogen 3.002 N/A SER 130.A N LYS 127.A O no hydrogen 2.896 N/A SER 130.A OG LYS 127.A O no hydrogen 2.774 N/A SER 130.A OG VAL 134.A O no hydrogen 3.537 N/A ILE 131.A N ASN 37.A OD1 no hydrogen 2.929 N/A VAL 134.A N SER 130.A OG no hydrogen 2.862 N/A GLU 140.A N PRO 136.A O no hydrogen 2.954 N/A LEU 141.A N ILE 137.A O no hydrogen 2.922 N/A LYS 142.A N VAL 138.A O no hydrogen 3.051 N/A LYS 142.A NZ ASP 314.A OD2 no hydrogen 3.408 N/A ASN 143.A N VAL 139.A O no hydrogen 2.942 N/A GLN 144.A N GLU 140.A O no hydrogen 2.872 N/A ASN 145.A N LYS 142.A O no hydrogen 2.710 N/A LYS 146.A N LEU 141.A O no hydrogen 2.984 N/A LYS 146.A NZ SER 95.A O no hydrogen 2.673 N/A LYS 146.A NZ GLN 144.A OE1 no hydrogen 3.114 N/A ASN 149.A N GLY 169.A O no hydrogen 3.265 N/A ASN 149.A ND2 GLY 169.A O no hydrogen 2.918 N/A ALA 150.A N ASP 314.A OD2 no hydrogen 3.167 N/A PHE 152.A N PHE 311.A O no hydrogen 3.059 N/A THR 153.A N THR 167.A O no hydrogen 2.831 N/A PHE 154.A N THR 309.A O no hydrogen 2.840 N/A TYR 155.A N PHE 165.A O no hydrogen 3.025 N/A TYR 155.A OH LYS 324.A O no hydrogen 2.725 N/A VAL 158.A N HIS 162.A O no hydrogen 3.020 N/A HIS 162.A N VAL 158.A O no hydrogen 3.184 N/A HIS 162.A ND1 THR 163.A O no hydrogen 2.688 N/A THR 163.A OG1 GLU 5.A OE1 no hydrogen 2.753 N/A GLY 164.A N LEU 6.A O no hydrogen 2.965 N/A PHE 165.A N TYR 155.A O no hydrogen 2.753 N/A LEU 166.A N ILE 4.A O no hydrogen 2.822 N/A THR 167.A N THR 153.A O no hydrogen 3.018 N/A ILE 168.A N ASP 2.A O no hydrogen 2.914 N/A GLY 169.A N LEU 151.A O no hydrogen 2.717 N/A ARG 174.A NH1 GLU 172.A OE1 no hydrogen 3.246 N/A PHE 175.A N GLU 172.A O no hydrogen 3.165 N/A TYR 176.A N GLU 173.A O no hydrogen 3.253 N/A GLU 177.A N LEU 322.A O no hydrogen 2.854 N/A THR 181.A N ILE 320.A O no hydrogen 2.964 N/A GLU 183.A N VAL 318.A O no hydrogen 2.952 N/A LEU 185.A N GLN 316.A O no hydrogen 2.968 N/A ASN 186.A N GLN 192.A O no hydrogen 2.859 N/A ASN 186.A ND2 THR 194.A OG1 no hydrogen 2.716 N/A ASN 186.A ND2 ASN 208.A OD1 no hydrogen 3.193 N/A LEU 189.A N HIS 187.A ND1 no hydrogen 3.425 N/A TRP 191.A NE1 LEU 124.A O no hydrogen 3.027 N/A GLN 192.A N TYR 190.A O no hydrogen 2.761 N/A GLN 192.A NE2 ASN 186.A OD1 no hydrogen 2.822 N/A ILE 193.A N CYS 209.A O no hydrogen 2.809 N/A LEU 195.A N ALA 207.A O no hydrogen 3.012 N/A ASP 196.A N THR 258.A O no hydrogen 2.913 N/A ALA 197.A N LEU 204.A O no hydrogen 2.897 N/A HIS 198.A N GLU 256.A O no hydrogen 2.765 N/A VAL 199.A N ILE 202.A O no hydrogen 2.854 N/A ILE 202.A N VAL 199.A O no hydrogen 2.961 N/A LEU 204.A N ALA 197.A O no hydrogen 2.762 N/A LYS 206.A N ASP 196.A OD1 no hydrogen 2.736 N/A ALA 207.A N LEU 195.A O no hydrogen 2.650 N/A ASN 208.A N PRO 295.A O no hydrogen 3.154 N/A CYS 209.A N ILE 193.A O no hydrogen 2.838 N/A CYS 209.A SG ALA 207.A O no hydrogen 3.945 N/A ILE 210.A N PHE 297.A O no hydrogen 2.929 N/A VAL 211.A N TRP 191.A O no hydrogen 2.963 N/A ASP 212.A N LEU 299.A O no hydrogen 3.115 N/A SER 213.A N THR 33.A OG1 no hydrogen 3.031 N/A SER 213.A OG LEU 31.A O no hydrogen 2.426 N/A GLY 214.A N ASP 212.A OD1.B no hydrogen 2.831 N/A THR 215.A OG1 ASP 212.A OD1.B no hydrogen 3.342 N/A THR 215.A OG1 ASP 212.A OD2.A no hydrogen 2.450 N/A SER 216.A OG.B ILE 12.A O no hydrogen 2.578 N/A SER 216.A OG.B ASP 301.A OD2.B no hydrogen 3.247 N/A ILE 218.A N ASN 286.A O no hydrogen 2.862 N/A THR 219.A N ILE 298.A O no hydrogen 3.047 N/A VAL 220.A N ILE 288.A O no hydrogen 2.860 N/A THR 222.A N ASP 291.A OD1 no hydrogen 2.931 N/A THR 222.A OG1 ASP 291.A OD1 no hydrogen 3.341 N/A THR 222.A OG1 ASP 291.A OD2 no hydrogen 2.538 N/A LEU 225.A N PRO 221.A O no hydrogen 2.933 N/A ASN 226.A N THR 222.A O no hydrogen 2.930 N/A LYS 227.A N ASP 223.A O no hydrogen 3.111 N/A LYS 227.A NZ ASP 223.A OD1 no hydrogen 3.514 N/A LYS 227.A NZ ASP 223.A OD2 no hydrogen 3.362 N/A MET 228.A N PHE 224.A O no hydrogen 2.904 N/A LEU 229.A N LEU 225.A O no hydrogen 2.892 N/A GLN 230.A N LYS 227.A O no hydrogen 3.381 N/A LEU 232.A N LEU 229.A O no hydrogen 3.195 N/A ILE 235.A N VAL 244.A O no hydrogen 2.896 N/A LYS 236.A NZ VAL 237.A O no hydrogen 3.006 N/A LYS 236.A NZ LEU 240.A O no hydrogen 2.875 N/A VAL 237.A N PHE 242.A O no hydrogen 2.848 N/A LEU 240.A N VAL 237.A O no hydrogen 3.282 N/A VAL 244.A N ILE 235.A O no hydrogen 2.763 N/A THR 245.A N CYS 283.A O no hydrogen 2.946 N/A THR 245.A OG1 LEU 246.A O no hydrogen 2.873 N/A CYS 247.A N GLY 281.A O no hydrogen 2.973 N/A CYS 247.A SG HIS 274.A ND1 no hydrogen 3.530 N/A ASN 249.A N LEU 246.A O no hydrogen 3.079 N/A ASN 249.A ND2 LEU 232.A O no hydrogen 2.735 N/A ASN 249.A ND2 THR 245.A OG1 no hydrogen 3.100 N/A LYS 251.A N ASN 249.A OD1 no hydrogen 3.007 N/A LYS 251.A NZ ASN 231.A O no hydrogen 2.777 N/A LYS 251.A NZ ASP 233.A OD2 no hydrogen 2.919 N/A LEU 252.A N ASN 249.A O no hydrogen 3.272 N/A PHE 255.A N LEU 266.A O no hydrogen 3.011 N/A GLU 256.A N HIS 198.A O no hydrogen 2.868 N/A PHE 257.A N TYR 264.A O no hydrogen 2.776 N/A THR 258.A N ASP 196.A O no hydrogen 2.957 N/A SER 259.A N GLY 262.A O no hydrogen 3.002 N/A SER 259.A OG GLU 183.A OE1 no hydrogen 3.192 N/A SER 259.A OG GLU 183.A OE2 no hydrogen 2.524 N/A GLY 262.A N SER 259.A OG no hydrogen 2.764 N/A LYS 263.A NZ GLU 256.A OE1 no hydrogen 2.786 N/A TYR 264.A N PHE 257.A O no hydrogen 2.794 N/A TYR 264.A OH GLU 183.A OE2 no hydrogen 2.521 N/A THR 265.A N TYR 307.A OH no hydrogen 2.781 N/A THR 265.A OG1 GLU 267.A OE1 no hydrogen 2.605 N/A LEU 266.A N PHE 255.A O no hydrogen 2.752 N/A GLU 267.A N GLU 267.A OE2 no hydrogen 2.782 N/A TYR 270.A N GLU 267.A O no hydrogen 2.929 N/A TYR 271.A N PRO 268.A O no hydrogen 2.955 N/A TYR 271.A OH PRO 253.A O no hydrogen 2.615 N/A LEU 272.A N PRO 268.A O no hydrogen 3.015 N/A GLN 273.A N MET 284.A O no hydrogen 2.829 N/A GLN 273.A NE2 GLN 10.A O no hydrogen 3.226 N/A GLN 273.A NE2 ASN 11.A O no hydrogen 3.567 N/A ILE 275.A N LEU 282.A O no hydrogen 2.971 N/A VAL 278.A N ILE 275.A O no hydrogen 2.742 N/A GLY 279.A N ILE 275.A O no hydrogen 3.339 N/A GLY 281.A N GLU 276.A OE1 no hydrogen 3.143 N/A CYS 283.A N THR 245.A O no hydrogen 2.791 N/A CYS 283.A SG HIS 274.A ND1 no hydrogen 3.548 N/A MET 284.A N GLN 273.A O no hydrogen 2.809 N/A LEU 285.A N TYR 243.A O no hydrogen 2.969 N/A ASN 286.A N TYR 271.A O no hydrogen 2.664 N/A ASN 286.A ND2 GLN 273.A OE1 no hydrogen 3.351 N/A ILE 288.A N ILE 218.A O no hydrogen 3.001 N/A LEU 290.A N VAL 220.A O no hydrogen 2.799 N/A THR 296.A OG1 VAL 294.A O no hydrogen 2.672 N/A PHE 297.A N ASN 208.A O no hydrogen 2.800 N/A ILE 298.A N THR 219.A O no hydrogen 3.217 N/A ILE 298.A N THR 219.A OG1 no hydrogen 3.159 N/A LEU 299.A N ILE 210.A O no hydrogen 2.785 N/A ASP 301.A N.A THR 215.A O no hydrogen 2.758 N/A ASP 301.A N.B THR 215.A O no hydrogen 2.791 N/A PHE 303.A N GLY 300.A O no hydrogen 2.847 N/A MET 304.A N GLY 300.A O no hydrogen 3.118 N/A ARG 305.A N ASP 301.A O.A no hydrogen 2.830 N/A ARG 305.A N ASP 301.A O.B no hydrogen 2.737 N/A ARG 305.A NE ASP 301.A OD1.A no hydrogen 3.237 N/A ARG 305.A NE ASP 301.A OD2.A no hydrogen 3.049 N/A ARG 305.A NH1 ASP 8.A OD1 no hydrogen 2.734 N/A ARG 305.A NH1 PRO 157.A O no hydrogen 2.760 N/A ARG 305.A NH2 ASP 301.A OD2.A no hydrogen 2.893 N/A LYS 306.A N PHE 303.A O no hydrogen 3.155 N/A LYS 306.A NZ THR 265.A O no hydrogen 2.767 N/A LYS 306.A NZ GLU 267.A OE1 no hydrogen 3.396 N/A LYS 306.A NZ GLU 267.A OE2 no hydrogen 2.876 N/A LYS 306.A NZ TYR 307.A OH no hydrogen 3.183 N/A TYR 307.A N PHE 303.A O no hydrogen 2.876 N/A TYR 307.A OH THR 265.A O no hydrogen 3.242 N/A THR 309.A N PHE 154.A O no hydrogen 3.207 N/A VAL 310.A N GLY 319.A O no hydrogen 2.807 N/A PHE 311.A N PHE 152.A O no hydrogen 2.667 N/A ASP 312.A N SER 317.A O no hydrogen 3.012 N/A TYR 313.A N ALA 150.A O no hydrogen 3.011 N/A TYR 313.A OH GLY 125.A O no hydrogen 2.781 N/A ASN 315.A N ASP 312.A OD1 no hydrogen 3.006 N/A ASN 315.A ND2 ASP 312.A OD2 no hydrogen 3.078 N/A GLN 316.A N TYR 313.A O no hydrogen 3.305 N/A SER 317.A N ASP 312.A O no hydrogen 3.159 N/A VAL 318.A N GLU 183.A O no hydrogen 2.891 N/A GLY 319.A N VAL 310.A O no hydrogen 2.848 N/A ILE 320.A N THR 181.A O no hydrogen 2.859 N/A ALA 321.A N PHE 308.A O no hydrogen 2.947 N/A ALA 323.A N LYS 306.A O no hydrogen 2.973 N/A LYS 324.A N PHE 175.A O no hydrogen 2.828 N/A LYS 325.A NZ TYR 270.A OH no hydrogen 3.353 N/A ASN 326.A ND2 LYS 161.A O no hydrogen 3.092 N/A