Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5yq4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 2.A N ASN 237.A OD1 no hydrogen 2.930 N/A VAL 3.A N ILE 283.A O no hydrogen 2.816 N/A LEU 4.A N TYR 22.A O no hydrogen 2.871 N/A PHE 5.A N GLY 281.A O no hydrogen 2.863 N/A ALA 6.A N GLU 20.A O no hydrogen 2.852 N/A VAL 7.A N GLY 279.A O no hydrogen 2.777 N/A GLY 8.A N SER 18.A O no hydrogen 2.819 N/A TRP 10.A N SER 18.A OG no hydrogen 3.082 N/A CYS 11.A SG SER 17.A OG no hydrogen 3.574 N/A CYS 11.A SG ARG 39.A O no hydrogen 3.650 N/A SER 12.A N ILE 16.A O no hydrogen 2.973 N/A SER 12.A OG ASP 14.A OD1 no hydrogen 2.588 N/A SER 12.A OG ILE 16.A O no hydrogen 3.473 N/A ALA 15.A N SER 12.A O no hydrogen 2.955 N/A ILE 16.A N SER 12.A OG no hydrogen 2.854 N/A SER 17.A OG ARG 39.A O no hydrogen 2.725 N/A SER 18.A N TRP 10.A O no hydrogen 2.891 N/A SER 18.A OG TRP 10.A O no hydrogen 3.356 N/A GLU 20.A N ALA 6.A O no hydrogen 2.830 N/A ARG 21.A N ARG 30.A O no hydrogen 2.781 N/A TYR 22.A N LEU 4.A O no hydrogen 2.737 N/A TYR 22.A OH ASN 27.A OD1 no hydrogen 2.749 N/A ASP 23.A N GLU 28.A O no hydrogen 3.001 N/A GLN 25.A N ASP 23.A OD1 no hydrogen 2.842 N/A THR 26.A OG1 ASP 23.A O no hydrogen 3.427 N/A GLU 28.A N ASP 23.A O no hydrogen 3.283 N/A ARG 30.A N ARG 21.A O no hydrogen 2.883 N/A VAL 32.A N VAL 19.A O no hydrogen 2.977 N/A ALA 33.A N ASN 74.A OD1 no hydrogen 3.108 N/A SER 36.A N GLU 67.A OE1 no hydrogen 2.766 N/A LYS 37.A N GLU 67.A OE2 no hydrogen 3.002 N/A ARG 38.A NH1 ASP 14.A O no hydrogen 2.837 N/A ARG 39.A N ALA 15.A O no hydrogen 2.872 N/A ARG 39.A NH1 ALA 53.A O no hydrogen 3.198 N/A ARG 39.A NH1 GLY 55.A O no hydrogen 2.735 N/A ARG 39.A NH2 ALA 53.A O no hydrogen 3.163 N/A ARG 39.A NH2 GLU 67.A OE2 no hydrogen 3.310 N/A CYS 40.A N HIS 57.A O no hydrogen 2.814 N/A GLY 43.A N VAL 54.A O no hydrogen 2.985 N/A SER 45.A N TYR 52.A O no hydrogen 3.141 N/A LEU 47.A N LEU 50.A O no hydrogen 2.964 N/A LEU 50.A N LEU 47.A O no hydrogen 3.069 N/A LEU 51.A N TYR 69.A O no hydrogen 2.974 N/A TYR 52.A N SER 45.A O no hydrogen 2.775 N/A ALA 53.A N GLU 67.A O no hydrogen 2.929 N/A VAL 54.A N GLY 43.A O no hydrogen 2.801 N/A GLY 55.A N SER 65.A O no hydrogen 2.867 N/A GLY 56.A N ARG 87.A O no hydrogen 2.930 N/A HIS 57.A N CYS 40.A O no hydrogen 2.816 N/A HIS 57.A ND1 THR 88.A OG1 no hydrogen 3.260 N/A ASP 58.A N SER 61.A O no hydrogen 2.798 N/A SER 61.A N ASP 58.A O no hydrogen 3.097 N/A SER 61.A OG.B ASP 58.A O no hydrogen 3.079 N/A LEU 63.A N GLY 56.A O no hydrogen 2.892 N/A GLU 67.A N ALA 53.A O no hydrogen 3.022 N/A ARG 68.A N SER 77.A O no hydrogen 2.977 N/A ARG 68.A NE ASP 79.A OD1 no hydrogen 2.863 N/A ARG 68.A NH1 TYR 52.A OH no hydrogen 2.970 N/A ARG 68.A NH2 ASP 79.A OD1 no hydrogen 3.420 N/A ARG 68.A NH2 ASP 79.A OD2 no hydrogen 2.884 N/A TYR 69.A N LEU 51.A O no hydrogen 2.759 N/A TYR 69.A OH ASN 74.A OD1 no hydrogen 2.546 N/A ASP 70.A N GLN 75.A O no hydrogen 3.000 N/A LYS 72.A N ASP 70.A OD1 no hydrogen 2.851 N/A LYS 72.A NZ ASP 70.A OD1 no hydrogen 2.593 N/A LYS 72.A NZ ASP 70.A OD2 no hydrogen 3.447 N/A THR 73.A N ASP 70.A O no hydrogen 3.150 N/A THR 73.A OG1 ASP 70.A O no hydrogen 3.388 N/A ASN 74.A N ASP 70.A O no hydrogen 2.831 N/A TRP 76.A NE1 ALA 33.A O no hydrogen 2.858 N/A SER 77.A N ARG 68.A O no hydrogen 2.839 N/A ALA 81.A N ASN 122.A OD1 no hydrogen 2.874 N/A THR 83.A N ASN 64.A O no hydrogen 3.012 N/A THR 83.A OG1 ASN 64.A O no hydrogen 3.316 N/A THR 83.A OG1 THR 85.A O no hydrogen 2.734 N/A SER 84.A N GLU 115.A OE1 no hydrogen 2.863 N/A SER 84.A OG GLU 115.A OE1 no hydrogen 2.885 N/A THR 85.A OG1 GLU 115.A OE2 no hydrogen 3.268 N/A CYS 86.A SG TYR 62.A O no hydrogen 3.659 N/A ARG 87.A N LEU 63.A O no hydrogen 3.019 N/A ARG 87.A NH1 ALA 101.A O no hydrogen 3.225 N/A ARG 87.A NH1 GLY 103.A O no hydrogen 2.735 N/A ARG 87.A NH2 ALA 101.A O no hydrogen 3.123 N/A ARG 87.A NH2 GLU 115.A OE2 no hydrogen 2.890 N/A THR 88.A N GLN 105.A O no hydrogen 2.916 N/A THR 88.A OG1 GLY 41.A O no hydrogen 3.339 N/A THR 88.A OG1 HIS 57.A ND1 no hydrogen 3.260 N/A SER 89.A N GLY 41.A O no hydrogen 3.082 N/A GLY 91.A N VAL 102.A O no hydrogen 2.936 N/A ALA 93.A N TYR 100.A O no hydrogen 3.179 N/A LEU 95.A N PHE 98.A O no hydrogen 2.900 N/A PHE 98.A N LEU 95.A O no hydrogen 3.148 N/A LEU 99.A N TYR 117.A O no hydrogen 3.071 N/A TYR 100.A N ALA 93.A O no hydrogen 2.825 N/A ALA 101.A N GLU 115.A O no hydrogen 2.865 N/A VAL 102.A N GLY 91.A O no hydrogen 2.757 N/A GLY 103.A N ILE 113.A O no hydrogen 2.839 N/A GLY 104.A N ARG 134.A O no hydrogen 2.917 N/A GLN 105.A N THR 88.A O no hydrogen 2.916 N/A ASP 106.A N SER 109.A O no hydrogen 3.096 N/A VAL 108.A N ASP 106.A OD1 no hydrogen 2.901 N/A SER 109.A N ASP 106.A OD1 no hydrogen 3.009 N/A SER 109.A OG CYS 110.A O no hydrogen 2.962 N/A CYS 110.A SG.B ASP 153.A O no hydrogen 3.528 N/A LEU 111.A N GLY 104.A O no hydrogen 2.929 N/A GLU 115.A N ALA 101.A O no hydrogen 3.035 N/A ARG 116.A N THR 125.A O no hydrogen 2.887 N/A ARG 116.A NH1.A TYR 100.A OH no hydrogen 3.047 N/A TYR 117.A N LEU 99.A O no hydrogen 2.728 N/A TYR 117.A OH ASN 122.A OD1 no hydrogen 2.654 N/A ASP 118.A N LYS 123.A O no hydrogen 2.944 N/A LYS 120.A N ASP 118.A OD1 no hydrogen 2.918 N/A LYS 123.A N ASP 118.A O no hydrogen 3.433 N/A TRP 124.A NE1 ALA 81.A O no hydrogen 2.834 N/A THR 125.A N ARG 116.A O no hydrogen 3.078 N/A VAL 127.A N VAL 114.A O no hydrogen 3.015 N/A ALA 128.A N ASN 169.A OD1 no hydrogen 3.193 N/A MET 130.A N ASN 112.A O no hydrogen 2.888 N/A SER 131.A N GLU 162.A OE2 no hydrogen 2.830 N/A SER 131.A OG.B GLU 162.A OE2 no hydrogen 2.927 N/A THR 132.A N GLU 162.A OE1 no hydrogen 3.335 N/A THR 132.A OG1 GLU 162.A OE1 no hydrogen 2.713 N/A ARG 134.A N LEU 111.A O no hydrogen 3.005 N/A ARG 134.A NH1 ALA 148.A O no hydrogen 3.280 N/A ARG 134.A NH1 GLY 150.A O no hydrogen 2.779 N/A ARG 134.A NH1 THR 160.A O no hydrogen 3.194 N/A ARG 134.A NH2 ALA 148.A O no hydrogen 3.197 N/A ARG 134.A NH2 GLU 162.A OE1 no hydrogen 2.865 N/A LEU 135.A N SER 152.A O no hydrogen 2.850 N/A GLY 136.A N SER 89.A O no hydrogen 2.952 N/A ALA 138.A N VAL 149.A O no hydrogen 3.056 N/A ALA 140.A N TYR 147.A O no hydrogen 3.108 N/A LEU 142.A N PHE 145.A O no hydrogen 3.026 N/A PHE 145.A N LEU 142.A O no hydrogen 3.142 N/A LEU 146.A N TYR 164.A O no hydrogen 3.100 N/A TYR 147.A N ALA 140.A O no hydrogen 2.744 N/A ALA 148.A N GLU 162.A O no hydrogen 2.855 N/A VAL 149.A N ALA 138.A O no hydrogen 2.787 N/A GLY 150.A N THR 160.A O no hydrogen 2.880 N/A GLY 151.A N ARG 181.A O no hydrogen 2.979 N/A SER 152.A N LEU 135.A O no hydrogen 2.944 N/A ASP 153.A N SER 156.A O no hydrogen 3.021 N/A GLY 154.A N SER 152.A OG.B no hydrogen 3.007 N/A THR 155.A N ASP 153.A OD1 no hydrogen 2.820 N/A SER 156.A N ASP 153.A OD1 no hydrogen 2.790 N/A LEU 158.A N GLY 151.A O no hydrogen 2.872 N/A GLU 162.A N ALA 148.A O no hydrogen 3.027 N/A ARG 163.A N HIS 172.A O no hydrogen 2.874 N/A ARG 163.A NH1 TYR 147.A OH no hydrogen 2.867 N/A TYR 164.A N LEU 146.A O no hydrogen 2.722 N/A TYR 164.A OH ASN 169.A OD1 no hydrogen 2.685 N/A ASN 165.A N ARG 170.A O no hydrogen 3.099 N/A GLN 167.A NE2 ASN 165.A OD1 no hydrogen 3.352 N/A GLU 168.A N ASN 165.A OD1 no hydrogen 3.026 N/A ARG 170.A N ASN 165.A O no hydrogen 3.371 N/A TRP 171.A NE1 ALA 128.A O no hydrogen 2.875 N/A HIS 172.A N ARG 163.A O no hydrogen 2.846 N/A ILE 174.A N VAL 161.A O no hydrogen 3.045 N/A ALA 175.A N ASN 216.A OD1 no hydrogen 3.162 N/A MET 177.A N ASN 159.A O no hydrogen 2.906 N/A GLY 178.A N GLU 209.A OE1 no hydrogen 2.802 N/A ARG 180.A NH1 PRO 157.A O no hydrogen 2.815 N/A ARG 181.A N LEU 158.A O no hydrogen 2.983 N/A ARG 181.A NE GLU 209.A OE2 no hydrogen 3.108 N/A ARG 181.A NH1 GLY 197.A O no hydrogen 2.922 N/A ARG 181.A NH1 SER 207.A O no hydrogen 3.090 N/A ARG 181.A NH1 SER 207.A OG no hydrogen 3.094 N/A ARG 181.A NH2 SER 207.A OG no hydrogen 3.051 N/A ARG 181.A NH2 GLU 209.A OE2 no hydrogen 2.883 N/A LYS 182.A N ARG 199.A O no hydrogen 2.998 N/A LYS 182.A NZ THR 155.A O no hydrogen 2.922 N/A GLY 185.A N VAL 196.A O no hydrogen 2.980 N/A CYS 186.A SG TYR 194.A O no hydrogen 3.593 N/A ALA 187.A N TYR 194.A O no hydrogen 3.041 N/A TYR 189.A N MET 192.A O no hydrogen 2.902 N/A MET 192.A N TYR 189.A O no hydrogen 3.041 N/A ILE 193.A N TYR 211.A O no hydrogen 3.094 N/A TYR 194.A N ALA 187.A O no hydrogen 2.835 N/A ALA 195.A N GLU 209.A O no hydrogen 2.823 N/A VAL 196.A N GLY 185.A O no hydrogen 2.924 N/A GLY 197.A N SER 207.A O no hydrogen 2.965 N/A GLY 198.A N ARG 228.A O no hydrogen 2.889 N/A ARG 199.A N LYS 182.A O no hydrogen 2.847 N/A ARG 199.A NH1 GLU 204.A OE2 no hydrogen 2.949 N/A ASP 200.A N THR 203.A O no hydrogen 3.052 N/A THR 202.A N ASP 200.A OD1 no hydrogen 2.863 N/A THR 202.A OG1 ASP 200.A OD1 no hydrogen 3.544 N/A THR 203.A N ASP 200.A OD1 no hydrogen 2.898 N/A THR 203.A OG1 GLU 204.A O no hydrogen 2.923 N/A LEU 205.A N GLY 198.A O no hydrogen 2.897 N/A GLU 209.A N ALA 195.A O no hydrogen 2.895 N/A ARG 210.A N SER 219.A O no hydrogen 2.952 N/A ARG 210.A NH1 TYR 194.A OH no hydrogen 2.891 N/A TYR 211.A N ILE 193.A O no hydrogen 2.760 N/A TYR 211.A OH ASN 216.A OD1 no hydrogen 2.700 N/A ASN 212.A N GLN 217.A O no hydrogen 2.979 N/A ARG 214.A N ASN 212.A OD1 no hydrogen 2.974 N/A THR 215.A N ASN 212.A O no hydrogen 3.298 N/A THR 215.A OG1 ASN 212.A O no hydrogen 3.355 N/A GLN 217.A N ASN 212.A O no hydrogen 3.460 N/A TRP 218.A NE1 ALA 175.A O no hydrogen 2.889 N/A SER 219.A N ARG 210.A O no hydrogen 2.867 N/A VAL 221.A N ALA 208.A O no hydrogen 2.908 N/A MET 224.A N SER 206.A O no hydrogen 2.868 N/A THR 225.A N GLU 256.A OE1 no hydrogen 2.823 N/A SER 226.A N GLU 256.A OE2 no hydrogen 3.109 N/A ARG 227.A NH1 GLU 204.A O no hydrogen 2.715 N/A ARG 228.A N LEU 205.A O no hydrogen 2.925 N/A ARG 228.A NE GLU 256.A OE2 no hydrogen 3.032 N/A ARG 228.A NH1 GLY 244.A O no hydrogen 2.846 N/A ARG 228.A NH1 THR 254.A O no hydrogen 3.007 N/A ARG 228.A NH2 THR 254.A OG1 no hydrogen 2.857 N/A ARG 228.A NH2 GLU 256.A OE2 no hydrogen 2.896 N/A SER 229.A N PHE 246.A O no hydrogen 2.820 N/A GLY 230.A N HIS 183.A O no hydrogen 2.805 N/A GLY 232.A N VAL 243.A O no hydrogen 3.058 N/A ALA 234.A N MET 241.A O no hydrogen 2.954 N/A VAL 236.A N GLN 239.A O no hydrogen 2.864 N/A ASN 237.A N GLU 2.A OE1 no hydrogen 2.801 N/A GLN 239.A N VAL 236.A O no hydrogen 3.040 N/A MET 241.A N ALA 234.A O no hydrogen 2.847 N/A ALA 242.A N GLU 256.A O no hydrogen 2.856 N/A VAL 243.A N GLY 232.A O no hydrogen 2.814 N/A GLY 244.A N THR 254.A O no hydrogen 3.098 N/A PHE 246.A N SER 229.A O no hydrogen 2.748 N/A ASP 247.A N THR 250.A O no hydrogen 3.026 N/A THR 249.A N ASP 247.A OD1 no hydrogen 2.654 N/A THR 250.A N ASP 247.A OD1 no hydrogen 2.929 N/A LEU 252.A N GLY 245.A O no hydrogen 2.893 N/A LYS 253.A NZ ASN 272.A OD1 no hydrogen 3.387 N/A LYS 253.A NZ TYR 273.A O no hydrogen 2.768 N/A LYS 253.A NZ ARG 274.A O no hydrogen 3.507 N/A ILE 255.A N TYR 268.A O no hydrogen 2.904 N/A GLU 256.A N ALA 242.A O no hydrogen 2.833 N/A VAL 257.A N ARG 266.A O no hydrogen 2.869 N/A PHE 258.A N LEU 240.A O no hydrogen 2.857 N/A ASP 259.A N THR 264.A O no hydrogen 2.766 N/A ALA 262.A N ASP 259.A OD1 no hydrogen 3.164 N/A ASN 263.A N PRO 260.A O no hydrogen 3.266 N/A THR 264.A N ASP 259.A O no hydrogen 3.203 N/A THR 264.A OG1 TRP 265.A O no hydrogen 3.549 N/A TRP 265.A NE1 VAL 222.A O no hydrogen 2.877 N/A ARG 266.A N VAL 257.A O no hydrogen 2.836 N/A ARG 266.A NE ASP 259.A OD2 no hydrogen 2.991 N/A ARG 266.A NH2 ASP 259.A OD2 no hydrogen 2.991 N/A TYR 268.A N ILE 255.A O no hydrogen 2.896 N/A GLY 270.A N LYS 253.A O no hydrogen 2.771 N/A TYR 273.A N MET 271.A O no hydrogen 2.795 N/A ARG 275.A NH1 ARG 274.A O no hydrogen 2.932 N/A GLY 277.A N GLU 20.A OE1 no hydrogen 2.891 N/A GLY 279.A N VAL 7.A O no hydrogen 2.942 N/A GLY 281.A N PHE 5.A O no hydrogen 2.929 N/A ILE 283.A N VAL 3.A O no hydrogen 2.923 N/A LYS 284.A NZ VAL 282.A O no hydrogen 3.142 N/A