Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6a9e_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 4.A N ASN 1.A OD1 no hydrogen 2.820 N/A ARG 6.A N PHE 3.A O no hydrogen 2.881 N/A ARG 6.A NH2 GLU 62.A OE1 no hydrogen 3.021 N/A ILE 7.A N GLU 4.A O no hydrogen 2.910 N/A GLU 9.A N LEU 5.A O no hydrogen 2.879 N/A GLY 10.A N ARG 6.A O no hydrogen 2.793 N/A TYR 16.A N THR 24.A O no hydrogen 3.066 N/A ASN 18.A N TYR 22.A O no hydrogen 2.934 N/A GLU 20.A N ASN 18.A OD1 no hydrogen 3.027 N/A GLY 21.A N ASN 18.A O no hydrogen 3.125 N/A TYR 23.A N THR 32.A O no hydrogen 2.929 N/A TYR 23.A OH PRO 35.A O no hydrogen 3.189 N/A THR 24.A N TYR 16.A O no hydrogen 2.970 N/A THR 24.A OG1 TYR 22.A O no hydrogen 3.443 N/A ILE 25.A N HIS 29.A O no hydrogen 2.717 N/A HIS 29.A N ILE 25.A O no hydrogen 2.882 N/A THR 32.A N TYR 23.A O no hydrogen 2.950 N/A SER 34.A N THR 32.A OG1 no hydrogen 3.139 N/A SER 34.A OG SER 36.A OG no hydrogen 2.678 N/A SER 36.A N SER 34.A OG no hydrogen 3.258 N/A SER 36.A OG SER 34.A OG no hydrogen 2.678 N/A ALA 40.A N LEU 37.A O no hydrogen 2.924 N/A LYS 41.A N LEU 37.A O no hydrogen 2.951 N/A SER 42.A OG ALA 39.A O no hydrogen 3.478 N/A ASP 45.A N LYS 41.A O no hydrogen 3.506 N/A LYS 46.A N SER 42.A O no hydrogen 2.920 N/A ALA 47.A N GLU 43.A O no hydrogen 2.890 N/A ILE 48.A N LEU 44.A O no hydrogen 2.927 N/A GLY 49.A N ASP 45.A O no hydrogen 2.618 N/A THR 52.A OG1 ASP 45.A OD1 no hydrogen 2.650 N/A GLY 54.A N THR 52.A OG1 no hydrogen 3.357 N/A THR 57.A N GLU 60.A OE1 no hydrogen 3.219 N/A LYS 58.A NZ LEU 236.A O no hydrogen 3.109 N/A GLU 60.A N THR 57.A OG1 no hydrogen 3.386 N/A ALA 61.A N THR 57.A O no hydrogen 3.086 N/A GLU 62.A N LYS 58.A O no hydrogen 2.912 N/A LYS 63.A N ASP 59.A O no hydrogen 2.874 N/A LEU 64.A N GLU 60.A O no hydrogen 2.882 N/A PHE 65.A N ALA 61.A O no hydrogen 2.899 N/A ASN 66.A N GLU 62.A O no hydrogen 2.937 N/A GLN 67.A N LYS 63.A O no hydrogen 2.873 N/A ASP 68.A N LEU 64.A O no hydrogen 2.885 N/A VAL 69.A N PHE 65.A O no hydrogen 2.953 N/A ASP 70.A N ASN 66.A O no hydrogen 2.909 N/A ALA 71.A N GLN 67.A O no hydrogen 2.886 N/A ALA 72.A N ASP 68.A O no hydrogen 2.892 N/A VAL 73.A N VAL 69.A O no hydrogen 2.929 N/A ARG 74.A N ASP 70.A O no hydrogen 2.939 N/A GLY 75.A N ALA 71.A O no hydrogen 2.911 N/A ILE 76.A N ALA 72.A O no hydrogen 2.903 N/A LEU 77.A N VAL 73.A O no hydrogen 2.936 N/A ARG 78.A N ARG 74.A O no hydrogen 2.906 N/A ASN 79.A N GLY 75.A O no hydrogen 2.768 N/A LYS 81.A NZ ALA 108.A O no hydrogen 3.372 N/A LYS 81.A NZ THR 111.A OG1 no hydrogen 2.652 N/A LEU 82.A N ASN 79.A OD1 no hydrogen 2.892 N/A LYS 83.A N ASN 79.A O no hydrogen 3.477 N/A LYS 83.A NZ ASP 87.A OD2 no hydrogen 3.229 N/A TYR 86.A N LEU 82.A O no hydrogen 2.845 N/A ASP 87.A N LYS 83.A O no hydrogen 2.903 N/A SER 88.A OG VAL 85.A O no hydrogen 2.938 N/A LEU 89.A N TYR 86.A O no hydrogen 3.086 N/A ASP 90.A N ASP 90.A OD1 no hydrogen 2.542 N/A ARG 93.A NE PHE 148.A O no hydrogen 2.504 N/A ARG 93.A NH2 PHE 148.A O no hydrogen 3.019 N/A ARG 93.A NH2 ARG 149.A O no hydrogen 2.634 N/A ARG 94.A N ASP 90.A O no hydrogen 2.705 N/A ARG 94.A NE LEU 89.A O no hydrogen 2.686 N/A ARG 94.A NH2 ASP 87.A O no hydrogen 3.219 N/A ALA 95.A N ALA 91.A O no hydrogen 2.905 N/A ALA 96.A N VAL 92.A O no hydrogen 2.946 N/A LEU 97.A N ARG 93.A O no hydrogen 2.940 N/A ILE 98.A N ARG 94.A O no hydrogen 2.883 N/A ASN 99.A N ALA 95.A O no hydrogen 2.869 N/A ASN 99.A ND2 ASP 8.A OD2 no hydrogen 2.792 N/A PHE 101.A N ILE 98.A O no hydrogen 2.861 N/A GLN 102.A N ASN 99.A O no hydrogen 2.918 N/A GLN 102.A NE2 THR 137.A OG1 no hydrogen 3.228 N/A GLY 109.A N GLY 106.A O no hydrogen 3.271 N/A PHE 110.A N VAL 107.A O no hydrogen 3.160 N/A SER 113.A OG ASN 127.A OD1 no hydrogen 2.968 N/A LEU 114.A N PHE 110.A O no hydrogen 2.960 N/A ARG 115.A N THR 111.A O no hydrogen 2.918 N/A GLN 117.A N LEU 114.A O no hydrogen 2.929 N/A GLN 118.A N ARG 115.A O no hydrogen 3.415 N/A LYS 119.A N LEU 116.A O no hydrogen 2.905 N/A ALA 124.A N ARG 120.A O no hydrogen 3.241 N/A ALA 125.A N TRP 121.A O no hydrogen 2.902 N/A VAL 126.A N ASP 122.A O no hydrogen 2.939 N/A ASN 127.A N GLU 123.A O no hydrogen 2.913 N/A LEU 128.A N ALA 124.A O no hydrogen 2.871 N/A ALA 129.A N ALA 125.A O no hydrogen 2.915 N/A LYS 130.A N ASN 127.A O no hydrogen 2.982 N/A SER 131.A OG LEU 128.A O no hydrogen 2.383 N/A TRP 133.A NE1 GLN 102.A OE1 no hydrogen 3.004 N/A ASN 135.A N SER 131.A O no hydrogen 3.241 N/A GLN 136.A N ARG 132.A O no hydrogen 2.909 N/A GLN 136.A NE2 THR 19.A O no hydrogen 3.310 N/A THR 137.A N TRP 133.A O no hydrogen 3.121 N/A THR 137.A OG1 THR 137.A O no hydrogen 2.572 N/A ARG 140.A NE ASN 99.A OD1 no hydrogen 3.145 N/A ARG 140.A NH1 GLU 9.A OE2 no hydrogen 2.442 N/A ARG 140.A NH2 ASN 99.A OD1 no hydrogen 2.763 N/A ALA 141.A N THR 137.A O no hydrogen 2.584 N/A LYS 142.A N PRO 138.A O no hydrogen 2.908 N/A ARG 143.A N ASN 139.A O no hydrogen 2.937 N/A ARG 143.A NH2 ASP 8.A OD1 no hydrogen 2.285 N/A VAL 144.A N ARG 140.A O no hydrogen 2.908 N/A ILE 145.A N ALA 141.A O no hydrogen 2.892 N/A THR 146.A N LYS 142.A O no hydrogen 2.912 N/A THR 146.A OG1 LYS 142.A O no hydrogen 2.390 N/A THR 147.A N ARG 143.A O no hydrogen 2.896 N/A THR 147.A OG1 ARG 143.A O no hydrogen 3.115 N/A PHE 148.A N VAL 144.A O no hydrogen 2.912 N/A ARG 149.A N ILE 145.A O no hydrogen 2.890 N/A THR 150.A N THR 146.A O no hydrogen 2.911 N/A THR 150.A OG1 THR 146.A O no hydrogen 2.934 N/A GLY 151.A N THR 147.A O no hydrogen 2.847 N/A THR 152.A OG1 ASP 154.A OD2 no hydrogen 3.432 N/A TYR 156.A OH ASP 8.A OD2 no hydrogen 2.713 N/A ARG 160.A N TYR 156.A O no hydrogen 2.916 N/A THR 161.A N ALA 157.A O no hydrogen 2.928 N/A THR 161.A OG1 ALA 157.A O no hydrogen 3.114 N/A VAL 162.A N ALA 158.A O no hydrogen 2.922 N/A GLN 163.A N ALA 159.A O no hydrogen 2.908 N/A ARG 164.A N ARG 160.A O no hydrogen 2.923 N/A ARG 164.A NH1 VAL 230.A O no hydrogen 3.308 N/A ARG 164.A NH2 VAL 230.A O no hydrogen 3.170 N/A ARG 165.A N THR 161.A O no hydrogen 2.968 N/A LEU 166.A N VAL 162.A O no hydrogen 2.885 N/A LEU 167.A N GLN 163.A O no hydrogen 2.898 N/A ALA 168.A N ARG 164.A O no hydrogen 2.940 N/A PHE 169.A N ARG 165.A O no hydrogen 2.979 N/A ALA 170.A N LEU 166.A O no hydrogen 2.890 N/A LEU 171.A N LEU 167.A O no hydrogen 2.908 N/A ARG 172.A N ALA 168.A O no hydrogen 2.951 N/A ARG 172.A NH2 GLU 271.A OE1 no hydrogen 3.265 N/A LYS 173.A N PHE 169.A O no hydrogen 2.935 N/A LEU 174.A N ALA 170.A O no hydrogen 2.907 N/A ILE 175.A N LEU 171.A O no hydrogen 2.901 N/A GLY 176.A N ARG 172.A O no hydrogen 2.922 N/A SER 177.A N LYS 173.A O no hydrogen 2.891 N/A SER 177.A OG LYS 173.A O no hydrogen 2.564 N/A ILE 178.A N LEU 174.A O no hydrogen 2.915 N/A LEU 179.A N ILE 175.A O no hydrogen 3.071 N/A LEU 180.A N GLN 202.A O no hydrogen 2.847 N/A ASN 182.A ND2 GLN 184.A OE1 no hydrogen 2.626 N/A GLU 186.A N GLU 186.A OE1 no hydrogen 2.657 N/A ASP 187.A N GLN 184.A O no hydrogen 3.147 N/A ASP 189.A N PRO 185.A O no hydrogen 2.906 N/A ILE 190.A N GLU 186.A O no hydrogen 2.909 N/A LEU 191.A N ASP 187.A O no hydrogen 2.928 N/A PHE 192.A N ILE 188.A O no hydrogen 2.927 N/A PHE 192.A N ASP 189.A O no hydrogen 3.281 N/A SER 193.A N ASP 189.A O no hydrogen 2.882 N/A SER 193.A OG ASP 189.A O no hydrogen 2.949 N/A SER 193.A OG ILE 190.A O no hydrogen 3.055 N/A LYS 194.A N ILE 190.A O no hydrogen 2.995 N/A LYS 194.A N SER 193.A OG no hydrogen 2.793 N/A LYS 194.A NZ SER 193.A OG no hydrogen 3.427 N/A LEU 197.A N LEU 226.A O no hydrogen 2.899 N/A ASN 200.A N ARG 222.A O no hydrogen 2.803 N/A LEU 201.A N LEU 221.A O no hydrogen 2.960 N/A GLN 202.A N GLU 181.A OE1 no hydrogen 3.197 N/A LEU 203.A N GLY 219.A O no hydrogen 2.494 N/A ASN 204.A N ILE 178.A O no hydrogen 2.692 N/A ASN 204.A ND2 SER 177.A O no hydrogen 3.343 N/A CYS 205.A SG THR 217.A O no hydrogen 3.767 N/A SER 206.A N ASN 204.A OD1 no hydrogen 3.091 N/A LEU 208.A N ASN 204.A O no hydrogen 3.201 N/A ASN 209.A N CYS 205.A O no hydrogen 2.912 N/A ASN 209.A ND2 PHE 216.A O no hydrogen 3.306 N/A ALA 210.A N SER 206.A O no hydrogen 2.922 N/A VAL 211.A N PHE 207.A O no hydrogen 2.886 N/A VAL 212.A N LEU 208.A O no hydrogen 2.894 N/A SER 213.A N ASN 209.A O no hydrogen 3.231 N/A ASN 215.A N GLU 250.A O no hydrogen 2.562 N/A PHE 216.A N ASN 209.A OD1 no hydrogen 2.682 N/A THR 217.A N GLU 248.A O no hydrogen 2.997 N/A THR 220.A N SER 246.A O no hydrogen 2.934 N/A ARG 222.A N GLY 244.A O no hydrogen 3.239 N/A ARG 223.A N ASN 243.A O no hydrogen 2.893 N/A LEU 224.A N LEU 198.A O no hydrogen 2.884 N/A ILE 225.A N GLU 241.A O no hydrogen 2.877 N/A LEU 226.A N LEU 197.A O no hydrogen 2.885 N/A ARG 227.A N GLU 239.A O no hydrogen 2.912 N/A LEU 228.A N GLY 195.A O no hydrogen 3.177 N/A ASN 229.A N ASN 237.A O no hydrogen 3.077 N/A ASN 229.A ND2 ASP 232.A O no hydrogen 3.415 N/A VAL 230.A N LEU 228.A O no hydrogen 2.736 N/A ASP 232.A N ASN 229.A O no hydrogen 3.109 N/A ASN 235.A N ASP 232.A OD1 no hydrogen 3.048 N/A VAL 238.A N SER 289.A O no hydrogen 3.379 N/A GLU 239.A N ARG 227.A O no hydrogen 2.896 N/A LEU 240.A N SER 291.A O no hydrogen 2.945 N/A GLU 241.A N ILE 225.A O no hydrogen 2.883 N/A VAL 242.A N LEU 293.A O no hydrogen 2.902 N/A ASN 243.A N ARG 223.A O no hydrogen 2.911 N/A GLY 244.A N GLN 294.A O no hydrogen 3.044 N/A LEU 247.A N LEU 297.A O no hydrogen 2.879 N/A GLU 248.A N LYS 218.A O no hydrogen 2.927 N/A ILE 249.A N TYR 299.A O no hydrogen 2.859 N/A GLU 250.A N ASN 215.A O no hydrogen 2.424 N/A VAL 257.A N LEU 254.A O no hydrogen 2.925 N/A GLU 259.A N ASP 255.A O no hydrogen 3.044 N/A TYR 260.A N ASN 256.A O no hydrogen 2.764 N/A LYS 262.A N GLU 259.A O no hydrogen 3.009 N/A THR 263.A N TYR 260.A O no hydrogen 2.998 N/A THR 263.A OG1 TYR 260.A O no hydrogen 3.367 N/A PHE 268.A N ALA 264.A O no hydrogen 2.573 N/A GLU 269.A N SER 265.A O no hydrogen 2.918 N/A ASP 270.A N GLN 266.A O no hydrogen 2.904 N/A GLU 271.A N ASP 267.A O no hydrogen 2.883 N/A VAL 272.A N PHE 268.A O no hydrogen 2.897 N/A ILE 273.A N GLU 269.A O no hydrogen 2.891 N/A ASN 274.A N ASP 270.A O no hydrogen 2.896 N/A GLU 275.A N GLU 271.A O no hydrogen 2.899 N/A GLY 276.A N ILE 273.A O no hydrogen 3.092 N/A SER 281.A N LEU 278.A O no hydrogen 3.062 N/A ILE 282.A N LEU 278.A O no hydrogen 3.481 N/A LEU 283.A N LEU 279.A O no hydrogen 2.892 N/A GLN 284.A N ASP 280.A O no hydrogen 2.896 N/A LYS 285.A N SER 281.A O no hydrogen 2.941 N/A LYS 285.A NZ VAL 234.A O no hydrogen 2.883 N/A CYS 286.A N ILE 282.A O no hydrogen 2.907 N/A LEU 287.A N LEU 283.A O no hydrogen 2.886 N/A ALA 288.A N GLN 284.A O no hydrogen 2.915 N/A SER 289.A N LYS 285.A O no hydrogen 2.908 N/A SER 289.A N CYS 286.A O no hydrogen 3.105 N/A SER 289.A OG LEU 236.A O no hydrogen 3.308 N/A SER 289.A OG LYS 285.A O no hydrogen 2.751 N/A SER 291.A N VAL 238.A O no hydrogen 2.862 N/A VAL 292.A N PHE 311.A O no hydrogen 2.976 N/A LEU 293.A N LEU 240.A O no hydrogen 2.889 N/A ASP 295.A N ASP 308.A O no hydrogen 2.990 N/A ALA 296.A N LEU 307.A O no hydrogen 2.885 N/A LEU 297.A N LEU 245.A O no hydrogen 2.899 N/A VAL 298.A N ALA 305.A O no hydrogen 2.891 N/A TYR 299.A N LEU 247.A O no hydrogen 2.921 N/A ILE 300.A N LEU 303.A O no hydrogen 2.919 N/A LEU 303.A N ILE 300.A O no hydrogen 2.904 N/A GLU 304.A N SER 328.A O no hydrogen 2.939 N/A ALA 305.A N VAL 298.A O no hydrogen 2.830 N/A LYS 306.A N THR 326.A O no hydrogen 2.907 N/A LEU 307.A N ALA 296.A O no hydrogen 2.941 N/A ASP 308.A N GLY 324.A O no hydrogen 3.377 N/A PHE 309.A N ASN 323.A O no hydrogen 2.934 N/A SER 310.A N ASN 321.A O no hydrogen 2.902 N/A PHE 311.A N VAL 292.A O no hydrogen 2.890 N/A SER 312.A N LEU 319.A O no hydrogen 2.967 N/A LEU 319.A N SER 312.A O no hydrogen 2.876 N/A ASN 321.A N SER 310.A O no hydrogen 2.962 N/A ASN 323.A N PHE 309.A O no hydrogen 2.862 N/A THR 326.A N LYS 306.A O no hydrogen 2.918 N/A SER 328.A N GLU 304.A O no hydrogen 2.858 N/A