Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6afn_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A N SER 2.A OG no hydrogen 3.022 N/A ARG 5.A NH1 ARG 265.A O no hydrogen 2.996 N/A ARG 5.A NH1 VAL 268.A O no hydrogen 2.868 N/A ASN 6.A N SER 2.A O no hydrogen 3.031 N/A VAL 7.A N HIS 3.A O no hydrogen 2.855 N/A ALA 8.A N MET 4.A O no hydrogen 2.978 N/A ALA 9.A N ARG 5.A O no hydrogen 2.926 N/A GLU 10.A N ASN 6.A O no hydrogen 2.972 N/A GLN 11.A N VAL 7.A O no hydrogen 3.000 N/A GLN 11.A NE2 GLU 15.A OE2 no hydrogen 3.042 N/A GLN 12.A N ALA 8.A O no hydrogen 2.916 N/A LEU 13.A N ALA 9.A O no hydrogen 2.863 N/A ARG 14.A N GLU 10.A O no hydrogen 3.046 N/A ARG 14.A NH2 GLN 11.A OE1 no hydrogen 2.342 N/A GLU 15.A N GLN 11.A O no hydrogen 2.991 N/A LEU 16.A N GLN 12.A O no hydrogen 2.883 N/A GLU 17.A N LEU 13.A O no hydrogen 2.920 N/A SER 18.A N ARG 14.A O no hydrogen 3.245 N/A SER 18.A N GLU 15.A O no hydrogen 3.125 N/A SER 18.A OG GLU 15.A O no hydrogen 2.617 N/A THR 19.A N LEU 16.A O no hydrogen 2.927 N/A THR 19.A OG1 LEU 16.A O no hydrogen 2.636 N/A PHE 20.A N GLU 17.A O no hydrogen 3.410 N/A ARG 23.A N THR 243.A OG1 no hydrogen 2.799 N/A ARG 23.A NH1 GLU 43.A OE1 no hydrogen 3.000 N/A LEU 24.A N GLU 17.A OE1 no hydrogen 2.800 N/A GLY 25.A N TYR 241.A O no hydrogen 2.814 N/A PHE 26.A N HIS 39.A O no hydrogen 2.868 N/A VAL 27.A N VAL 239.A O no hydrogen 3.009 N/A ALA 28.A N ILE 37.A O no hydrogen 2.892 N/A LEU 29.A N VAL 237.A O no hydrogen 2.955 N/A ASP 30.A N ALA 35.A O no hydrogen 2.932 N/A THR 31.A N PRO 235.A O no hydrogen 3.064 N/A THR 31.A OG1 PRO 235.A O no hydrogen 2.716 N/A ALA 32.A N ASP 30.A OD1 no hydrogen 2.993 N/A THR 33.A N ASP 30.A O no hydrogen 3.188 N/A GLY 34.A N ASP 30.A O no hydrogen 2.723 N/A ALA 35.A N THR 33.A OG1 no hydrogen 3.116 N/A ILE 37.A N ALA 28.A O no hydrogen 2.926 N/A ALA 38.A N GLU 10.A OE2 no hydrogen 2.928 N/A HIS 39.A N PHE 26.A O no hydrogen 2.881 N/A HIS 39.A ND1 LEU 24.A O no hydrogen 2.893 N/A ARG 40.A NE GLU 17.A OE1 no hydrogen 2.744 N/A ARG 40.A NH1 GLU 43.A OE2 no hydrogen 2.768 N/A ARG 40.A NH2 GLU 17.A OE2 no hydrogen 2.951 N/A GLU 43.A N ARG 40.A O no hydrogen 3.271 N/A ARG 44.A NH1 THR 138.A O no hydrogen 3.065 N/A ARG 44.A NH1 THR 159.A OG1 no hydrogen 2.869 N/A ARG 44.A NH2 THR 138.A O no hydrogen 2.945 N/A PHE 45.A N THR 160.A O no hydrogen 2.915 N/A PHE 47.A N ASP 158.A O no hydrogen 3.250 N/A SER 49.A OG SER 109.A OG no hydrogen 3.087 N/A THR 50.A N PHE 47.A O no hydrogen 3.111 N/A THR 50.A OG1 PHE 47.A O no hydrogen 2.725 N/A THR 50.A OG1 TYR 241.A OH no hydrogen 2.803 N/A PHE 51.A N TYR 48.A O no hydrogen 3.410 N/A LYS 52.A N SER 49.A O no hydrogen 2.964 N/A LYS 52.A NZ SER 49.A OG no hydrogen 2.752 N/A LYS 52.A NZ SER 109.A O no hydrogen 2.839 N/A LYS 52.A NZ ASN 111.A OD1 no hydrogen 2.738 N/A LYS 52.A NZ GLU 145.A OE2 no hydrogen 3.488 N/A THR 53.A N THR 50.A O no hydrogen 3.258 N/A LEU 55.A N PHE 51.A O no hydrogen 2.934 N/A SER 56.A N LYS 52.A O no hydrogen 2.951 N/A SER 56.A OG LYS 52.A O no hydrogen 2.952 N/A ALA 57.A N THR 53.A O no hydrogen 2.972 N/A ALA 58.A N MET 54.A O no hydrogen 3.002 N/A VAL 59.A N LEU 55.A O no hydrogen 3.066 N/A LEU 60.A N SER 56.A O no hydrogen 2.876 N/A ALA 61.A N ALA 57.A O no hydrogen 2.818 N/A ARG 62.A N.A ALA 58.A O no hydrogen 3.145 N/A ARG 62.A N.B ALA 58.A O no hydrogen 3.141 N/A ARG 62.A NH1.A LEU 120.A O no hydrogen 2.891 N/A ARG 62.A NH2.B LEU 121.A O no hydrogen 3.345 N/A SER 63.A N VAL 59.A O no hydrogen 2.924 N/A SER 63.A OG LEU 60.A O no hydrogen 2.672 N/A ALA 64.A N LEU 60.A O no hydrogen 3.092 N/A ALA 64.A N ALA 61.A O no hydrogen 3.275 N/A GLY 65.A N ARG 62.A O.A no hydrogen 3.156 N/A GLY 65.A N ARG 62.A O.B no hydrogen 3.149 N/A ASP 66.A N SER 63.A O no hydrogen 3.193 N/A ALA 68.A N ASP 66.A OD1 no hydrogen 3.163 N/A LEU 69.A N ASP 66.A O no hydrogen 3.083 N/A GLN 71.A N ALA 68.A O no hydrogen 3.025 N/A ARG 72.A N LEU 69.A O no hydrogen 3.026 N/A ILE 74.A N.A MET 96.A O no hydrogen 2.832 N/A ILE 74.A N.B MET 96.A O no hydrogen 2.852 N/A TYR 76.A OH THR 88.A O no hydrogen 2.630 N/A ALA 77.A N ASP 80.A OD2 no hydrogen 2.762 N/A ASP 80.A N ALA 77.A O no hydrogen 2.922 N/A LEU 81.A N LYS 78.A O no hydrogen 3.096 N/A VAL 82.A N THR 112.A OG1 no hydrogen 2.953 N/A TYR 84.A OH TYR 108.A O no hydrogen 2.823 N/A SER 85.A OG VAL 82.A O no hydrogen 2.815 N/A SER 85.A OG THR 112.A OG1 no hydrogen 2.615 N/A ILE 87.A N ASP 110.A OD2 no hydrogen 2.805 N/A THR 88.A N ASP 110.A OD2 no hydrogen 2.871 N/A THR 88.A OG1 ASP 110.A OD1 no hydrogen 2.808 N/A THR 88.A OG1 ASP 110.A OD2 no hydrogen 3.227 N/A GLU 89.A N SER 85.A O no hydrogen 3.072 N/A LYS 90.A N ILE 87.A O no hydrogen 2.947 N/A HIS 91.A N THR 88.A O no hydrogen 3.050 N/A GLY 93.A N TYR 76.A O no hydrogen 2.801 N/A GLY 95.A N HIS 91.A O no hydrogen 3.016 N/A MET 96.A N ILE 74.A O.A no hydrogen 3.328 N/A MET 96.A N ILE 74.A O.B no hydrogen 3.333 N/A THR 97.A N GLU 100.A OE1 no hydrogen 2.911 N/A VAL 98.A N ARG 72.A O no hydrogen 2.903 N/A ALA 99.A N LEU 70.A O no hydrogen 2.919 N/A GLU 100.A N THR 97.A OG1 no hydrogen 3.148 N/A LEU 101.A N THR 97.A O no hydrogen 2.858 N/A CYS 102.A N VAL 98.A O no hydrogen 2.940 N/A CYS 102.A SG VAL 98.A O no hydrogen 3.513 N/A ALA 103.A N ALA 99.A O no hydrogen 2.950 N/A ALA 104.A N GLU 100.A O no hydrogen 2.914 N/A THR 105.A N.A LEU 101.A O no hydrogen 2.899 N/A THR 105.A N.B LEU 101.A O no hydrogen 2.871 N/A THR 105.A OG1.A ASP 110.A O no hydrogen 2.861 N/A THR 105.A OG1.B LEU 101.A O no hydrogen 2.255 N/A LEU 106.A N CYS 102.A O no hydrogen 2.912 N/A GLN 107.A N ALA 103.A O no hydrogen 2.821 N/A GLN 107.A NE2 TRP 189.A O no hydrogen 2.875 N/A TYR 108.A N ALA 104.A O no hydrogen 3.042 N/A SER 109.A OG SER 49.A OG no hydrogen 3.087 N/A ASP 110.A N ALA 104.A O no hydrogen 3.272 N/A ASN 111.A N TYR 84.A O no hydrogen 2.963 N/A ASN 111.A ND2 ARG 83.A O.A no hydrogen 2.898 N/A ASN 111.A ND2 ARG 83.A O.B no hydrogen 2.877 N/A THR 112.A N SER 85.A OG no hydrogen 3.250 N/A THR 112.A OG1 SER 85.A OG no hydrogen 2.615 N/A ALA 113.A N ASP 110.A OD1 no hydrogen 2.953 N/A ALA 114.A N ASP 110.A O no hydrogen 3.337 N/A ASN 115.A N ASN 111.A O no hydrogen 3.055 N/A ASN 115.A ND2 GLU 145.A O no hydrogen 2.961 N/A LEU 116.A N THR 112.A O no hydrogen 2.873 N/A LEU 117.A N ALA 113.A O no hydrogen 3.027 N/A ILE 118.A N ALA 114.A O no hydrogen 2.825 N/A ALA 119.A N ASN 115.A O no hydrogen 2.968 N/A LEU 120.A N LEU 116.A O no hydrogen 2.932 N/A LEU 121.A N LEU 117.A O no hydrogen 3.099 N/A GLY 122.A N ALA 119.A O no hydrogen 3.045 N/A GLY 123.A N ILE 118.A O no hydrogen 2.934 N/A GLN 125.A N GLN 125.A OE1 no hydrogen 2.821 N/A GLN 125.A NE2 GLY 122.A O no hydrogen 2.707 N/A ALA 126.A N GLY 123.A O no hydrogen 2.997 N/A VAL 127.A N PRO 124.A O no hydrogen 2.932 N/A THR 128.A N PRO 124.A O no hydrogen 3.351 N/A THR 128.A OG1 LEU 141.A O no hydrogen 3.370 N/A ALA 129.A N GLN 125.A O no hydrogen 2.917 N/A TYR 130.A N ALA 126.A O no hydrogen 2.982 N/A ALA 131.A N VAL 127.A O no hydrogen 2.956 N/A ARG 132.A N THR 128.A O no hydrogen 3.014 N/A ARG 132.A NH1 ASP 136.A O no hydrogen 2.850 N/A ARG 132.A NH1 PHE 139.A O no hydrogen 2.828 N/A ARG 132.A NH2 PHE 139.A O no hydrogen 3.270 N/A SER 133.A N ALA 129.A O no hydrogen 3.073 N/A SER 133.A OG TYR 130.A O no hydrogen 2.638 N/A ILE 134.A N TYR 130.A O no hydrogen 3.251 N/A ILE 134.A N ALA 131.A O no hydrogen 3.166 N/A GLY 135.A N ARG 132.A O no hydrogen 2.987 N/A ASP 136.A N ALA 131.A O no hydrogen 2.925 N/A THR 138.A N ASP 136.A OD1 no hydrogen 2.924 N/A PHE 139.A N ASP 136.A OD1 no hydrogen 2.904 N/A ARG 140.A N THR 159.A O no hydrogen 3.274 N/A ARG 140.A NE ASP 142.A OD2 no hydrogen 2.929 N/A ARG 140.A NH2 ASP 142.A OD1 no hydrogen 2.924 N/A LEU 141.A N THR 128.A OG1 no hydrogen 2.984 N/A ASP 142.A N ASP 158.A OD1 no hydrogen 2.739 N/A ARG 143.A N ASP 158.A OD1 no hydrogen 3.097 N/A ARG 143.A NE ASP 158.A OD2 no hydrogen 2.762 N/A ARG 143.A NH1 THR 150.A OG1 no hydrogen 2.830 N/A ARG 143.A NH2 THR 150.A OG1 no hydrogen 3.120 N/A ARG 143.A NH2 ASP 158.A OD2 no hydrogen 2.866 N/A GLU 145.A N ASN 115.A OD1 no hydrogen 2.916 N/A GLU 147.A N GLU 147.A OE1 no hydrogen 2.851 N/A LEU 148.A N ARG 144.A O no hydrogen 3.091 N/A ASN 149.A N THR 146.A O no hydrogen 3.117 N/A ASN 149.A ND2 GLU 145.A OE1 no hydrogen 2.853 N/A ASN 149.A ND2 THR 146.A O no hydrogen 3.008 N/A THR 150.A N GLU 147.A O no hydrogen 3.308 N/A THR 150.A OG1 GLU 147.A O no hydrogen 3.504 N/A ASP 155.A N ILE 152.A O no hydrogen 2.992 N/A ARG 157.A N ASP 155.A OD1 no hydrogen 2.998 N/A ARG 157.A NE ASP 155.A OD1 no hydrogen 3.090 N/A ARG 157.A NE ASP 155.A OD2 no hydrogen 3.100 N/A ARG 157.A NH1 ASP 155.A OD2 no hydrogen 2.847 N/A ASP 158.A N ASP 142.A OD2 no hydrogen 3.025 N/A THR 159.A OG1 GLU 156.A O no hydrogen 2.651 N/A THR 160.A N PHE 45.A O no hydrogen 3.179 N/A ALA 163.A N ALA 41.A O no hydrogen 2.899 N/A ALA 164.A N THR 161.A OG1 no hydrogen 3.041 N/A MET 165.A N THR 161.A O no hydrogen 3.010 N/A ALA 166.A N PRO 162.A O no hydrogen 2.932 N/A ALA 167.A N ALA 163.A O no hydrogen 3.059 N/A SER 168.A N ALA 164.A O no hydrogen 2.984 N/A SER 168.A OG ASP 136.A OD2 no hydrogen 2.689 N/A SER 168.A OG ALA 164.A O no hydrogen 3.396 N/A VAL 169.A N MET 165.A O no hydrogen 2.816 N/A ARG 170.A N ALA 166.A O no hydrogen 2.934 N/A ARG 171.A N ALA 167.A O no hydrogen 3.008 N/A ARG 171.A NH1.B ILE 134.A O no hydrogen 3.152 N/A LEU 172.A N SER 168.A O no hydrogen 2.867 N/A LEU 173.A N.A VAL 169.A O no hydrogen 2.885 N/A LEU 173.A N.B VAL 169.A O no hydrogen 2.876 N/A VAL 174.A N.A ARG 170.A O no hydrogen 2.912 N/A VAL 174.A N.B ARG 170.A O no hydrogen 2.893 N/A ALA 177.A N ARG 171.A O no hydrogen 3.110 N/A ARG 183.A N GLY 179.A O no hydrogen 2.860 N/A ARG 183.A NE LEU 173.A O.A no hydrogen 2.886 N/A ARG 183.A NE LEU 173.A O.B no hydrogen 2.941 N/A ALA 184.A N THR 180.A O no hydrogen 3.013 N/A GLN 185.A N ALA 181.A O no hydrogen 3.024 N/A LEU 186.A N GLN 182.A O no hydrogen 2.939 N/A ASN 187.A N ARG 183.A O no hydrogen 2.998 N/A ASN 187.A ND2 LEU 173.A O.A no hydrogen 2.926 N/A ASN 187.A ND2 LEU 173.A O.B no hydrogen 2.933 N/A ASN 187.A ND2 ARG 183.A O no hydrogen 3.300 N/A ALA 188.A N ALA 184.A O no hydrogen 2.843 N/A TRP 189.A N GLN 185.A O no hydrogen 2.946 N/A MET 190.A N LEU 186.A O no hydrogen 3.000 N/A LEU 191.A N ASN 187.A O no hydrogen 2.785 N/A GLY 192.A N ALA 188.A O no hydrogen 3.282 N/A GLY 192.A N TRP 189.A O no hydrogen 3.106 N/A ASN 193.A N MET 190.A O no hydrogen 3.198 N/A ASN 193.A ND2 THR 195.A OG1 no hydrogen 3.198 N/A ASN 193.A ND2 ASP 212.A OD1 no hydrogen 3.018 N/A ASN 193.A ND2 ASP 212.A OD2 no hydrogen 3.188 N/A LYS 194.A N GLN 107.A O no hydrogen 2.981 N/A LYS 194.A NZ GLY 192.A O no hydrogen 2.978 N/A THR 195.A N ASN 193.A OD1 no hydrogen 3.184 N/A THR 195.A OG1 ASN 193.A OD1 no hydrogen 3.109 N/A THR 195.A OG1 THR 214.A OG1 no hydrogen 2.691 N/A ARG 199.A N GLY 196.A O no hydrogen 3.084 N/A ARG 199.A NE ASP 253.A OD1 no hydrogen 2.776 N/A ARG 199.A NH1 GLY 215.A O no hydrogen 2.814 N/A ARG 199.A NH1 THR 216.A OG1.A no hydrogen 3.333 N/A ARG 199.A NH1 ASN 223.A O no hydrogen 2.872 N/A ARG 199.A NH2 THR 216.A OG1.A no hydrogen 3.023 N/A ILE 200.A N ASP 224.A OD2 no hydrogen 2.962 N/A ARG 201.A NE ASP 212.A OD1 no hydrogen 3.021 N/A ARG 201.A NH2 LEU 191.A O no hydrogen 3.518 N/A ARG 201.A NH2 ASP 212.A OD1 no hydrogen 2.950 N/A ALA 202.A N ARG 199.A O no hydrogen 2.909 N/A GLY 203.A N ILE 200.A O no hydrogen 2.891 N/A TRP 208.A N PRO 205.A O no hydrogen 3.100 N/A ARG 209.A N TYR 229.A O no hydrogen 3.042 N/A ALA 211.A N VAL 227.A O no hydrogen 2.861 N/A ASP 212.A N MET 190.A O no hydrogen 3.307 N/A LYS 213.A N ILE 225.A O no hydrogen 2.819 N/A LYS 213.A NZ SER 109.A OG no hydrogen 2.830 N/A LYS 213.A NZ THR 214.A O no hydrogen 2.800 N/A THR 214.A OG1 THR 195.A OG1 no hydrogen 2.691 N/A GLY 215.A N ASN 223.A O no hydrogen 3.066 N/A GLY 217.A N THR 221.A O.A no hydrogen 3.334 N/A GLY 217.A N THR 221.A O.B no hydrogen 3.181 N/A THR 221.A N.A ASP 218.A O no hydrogen 3.246 N/A THR 221.A N.B ASP 218.A O no hydrogen 3.240 N/A THR 221.A OG1.A MET 244.A O no hydrogen 3.148 N/A THR 221.A OG1.B ASP 218.A O no hydrogen 2.759 N/A THR 221.A OG1.B MET 244.A O no hydrogen 2.839 N/A ASN 223.A N GLY 215.A O no hydrogen 2.890 N/A ASN 223.A ND2 PRO 46.A O no hydrogen 3.598 N/A ASN 223.A ND2 PHE 47.A O no hydrogen 3.173 N/A ASP 224.A N VAL 240.A O no hydrogen 2.997 N/A ILE 225.A N LYS 213.A O no hydrogen 3.026 N/A GLY 226.A N PHE 238.A O no hydrogen 2.832 N/A VAL 227.A N ALA 211.A O no hydrogen 2.891 N/A ALA 228.A N ILE 236.A O no hydrogen 2.844 N/A TYR 229.A N ARG 209.A O no hydrogen 2.692 N/A TYR 229.A OH ASN 187.A OD1 no hydrogen 2.688 N/A ARG 233.A NH2 ASP 30.A OD2 no hydrogen 2.611 N/A ILE 236.A N ALA 228.A O no hydrogen 2.954 N/A VAL 237.A N LEU 29.A O no hydrogen 2.893 N/A PHE 238.A N GLY 226.A O no hydrogen 2.848 N/A VAL 239.A N VAL 27.A O no hydrogen 2.808 N/A VAL 240.A N ASP 224.A O no hydrogen 2.870 N/A TYR 241.A N GLY 25.A O no hydrogen 2.763 N/A TYR 241.A OH THR 50.A OG1 no hydrogen 2.803 N/A THR 242.A OG1 GLY 222.A O no hydrogen 2.913 N/A THR 243.A N ARG 23.A O no hydrogen 2.972 N/A MET 244.A N THR 242.A OG1 no hydrogen 3.186 N/A SER 246.A N TYR 219.A O no hydrogen 3.301 N/A SER 246.A OG GLY 220.A O no hydrogen 3.330 N/A GLN 250.A NE2 ASP 254.A OD2 no hydrogen 2.397 N/A ALA 251.A N ASN 248.A OD1 no hydrogen 2.843 N/A ARG 252.A NH2 ASP 253.A OD1 no hydrogen 3.006 N/A ASP 253.A N ALA 249.A O no hydrogen 2.878 N/A ASP 254.A N GLN 250.A O no hydrogen 2.865 N/A VAL 255.A N ALA 251.A O no hydrogen 3.273 N/A ILE 256.A N ARG 252.A O no hydrogen 3.333 N/A ALA 257.A N ASP 253.A O no hydrogen 2.897 N/A SER 258.A N.A ASP 254.A O no hydrogen 2.879 N/A SER 258.A N.B ASP 254.A O no hydrogen 2.880 N/A SER 258.A OG.A ASP 254.A O no hydrogen 2.878 N/A ALA 259.A N VAL 255.A O no hydrogen 2.975 N/A ALA 260.A N ILE 256.A O no hydrogen 3.152 N/A ARG 261.A N ALA 257.A O no hydrogen 2.901 N/A ARG 261.A NH2 ALA 202.A O no hydrogen 3.157 N/A ILE 262.A N SER 258.A O.A no hydrogen 2.978 N/A ILE 262.A N SER 258.A O.B no hydrogen 3.064 N/A ALA 263.A N ALA 259.A O no hydrogen 3.351 N/A ALA 264.A N ALA 260.A O no hydrogen 2.887 N/A ARG 265.A N ARG 261.A O no hydrogen 2.941 N/A ALA 266.A N ILE 262.A O no hydrogen 3.313 N/A PHE 267.A N ALA 263.A O no hydrogen 3.034 N/A PHE 267.A N ALA 264.A O no hydrogen 3.251 N/A VAL 268.A N ALA 264.A O no hydrogen 3.083 N/A