Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6c0f_p.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 3.A N THR 22.A O no hydrogen 2.762 N/A SER 9.A OG THR 12.A OG1 no hydrogen 2.941 N/A THR 12.A OG1 SER 9.A O no hydrogen 2.285 N/A THR 12.A OG1 SER 9.A OG no hydrogen 2.941 N/A LEU 13.A N SER 9.A O no hydrogen 2.989 N/A LYS 14.A N GLN 10.A O no hydrogen 2.904 N/A ALA 15.A N PRO 11.A O no hydrogen 2.868 N/A ILE 16.A N THR 12.A O no hydrogen 2.901 N/A GLU 17.A N LEU 13.A O no hydrogen 2.930 N/A LYS 18.A N LYS 14.A O no hydrogen 2.923 N/A MET 19.A N ALA 15.A O no hydrogen 2.865 N/A GLY 20.A N GLU 17.A O no hydrogen 3.227 N/A PHE 21.A N ILE 16.A O no hydrogen 3.112 N/A ALA 29.A N THR 25.A O no hydrogen 2.726 N/A ARG 30.A N SER 26.A O no hydrogen 2.873 N/A THR 31.A N VAL 27.A O no hydrogen 2.940 N/A THR 31.A OG1 VAL 27.A O no hydrogen 3.160 N/A THR 31.A OG1 GLN 28.A O no hydrogen 3.284 N/A ILE 32.A N GLN 28.A O no hydrogen 2.944 N/A LEU 35.A N THR 31.A O no hydrogen 2.873 N/A LEU 36.A N ILE 32.A O no hydrogen 2.820 N/A GLY 38.A N PRO 34.A O no hydrogen 3.177 N/A VAL 41.A N SER 183.A O no hydrogen 3.065 N/A ALA 44.A N ILE 209.A O no hydrogen 3.354 N/A SER 49.A N LYS 46.A O no hydrogen 3.204 N/A SER 49.A OG LYS 46.A O no hydrogen 3.525 N/A LYS 51.A NZ GLU 156.A OE2 no hydrogen 2.508 N/A ALA 54.A N GLY 50.A O no hydrogen 3.120 N/A PHE 55.A N THR 52.A O no hydrogen 3.096 N/A LEU 56.A N THR 52.A O no hydrogen 2.927 N/A ILE 57.A N LEU 53.A O no hydrogen 3.018 N/A ALA 59.A N PHE 55.A O no hydrogen 3.120 N/A ILE 60.A N LEU 56.A O no hydrogen 3.288 N/A GLU 61.A N ILE 57.A O no hydrogen 2.972 N/A LEU 62.A N PRO 58.A O no hydrogen 2.849 N/A LEU 63.A N ALA 59.A O no hydrogen 2.963 N/A HIS 64.A N ILE 60.A O no hydrogen 2.837 N/A SER 65.A N GLU 61.A O no hydrogen 2.843 N/A SER 65.A OG GLU 61.A O no hydrogen 3.178 N/A SER 65.A OG LEU 62.A O no hydrogen 2.850 N/A LEU 66.A N LEU 62.A O no hydrogen 2.950 N/A LYS 67.A N LEU 63.A O no hydrogen 2.911 N/A ASN 72.A N LYS 69.A O no hydrogen 3.023 N/A THR 74.A OG1 VAL 145.A O no hydrogen 3.480 N/A VAL 78.A N LEU 127.A O no hydrogen 2.847 N/A ILE 79.A N ILE 153.A O no hydrogen 2.939 N/A THR 80.A N ALA 129.A O no hydrogen 3.149 N/A THR 82.A OG1 ASP 316.A OD1 no hydrogen 3.272 N/A THR 82.A OG1 ASP 316.A OD2 no hydrogen 3.560 N/A ALA 86.A N THR 82.A O no hydrogen 2.769 N/A LEU 87.A N ARG 83.A O no hydrogen 2.908 N/A GLN 88.A N GLU 84.A O no hydrogen 2.924 N/A ILE 89.A N LEU 85.A O no hydrogen 2.892 N/A PHE 90.A N ALA 86.A O no hydrogen 2.878 N/A GLY 91.A N LEU 87.A O no hydrogen 2.849 N/A VAL 92.A N GLN 88.A O no hydrogen 2.961 N/A ALA 93.A N ILE 89.A O no hydrogen 2.906 N/A MET 97.A N ALA 93.A O no hydrogen 2.922 N/A PHE 99.A N GLU 95.A O no hydrogen 3.008 N/A HIS 100.A N LEU 96.A O no hydrogen 3.398 N/A GLN 102.A NE2 PHE 68.A O no hydrogen 2.909 N/A GLY 105.A N MET 126.A O no hydrogen 3.132 N/A VAL 107.A N ILE 128.A O no hydrogen 3.074 N/A ILE 108.A N GLU 116.A OE2 no hydrogen 2.557 N/A ALA 111.A N ILE 108.A O no hydrogen 2.942 N/A GLU 116.A N ASN 112.A O no hydrogen 3.166 N/A ALA 117.A N ARG 113.A O no hydrogen 2.834 N/A GLU 118.A N ARG 114.A O no hydrogen 2.883 N/A LYS 119.A N GLN 115.A O no hydrogen 2.978 N/A LEU 120.A N GLU 116.A O no hydrogen 2.909 N/A MET 121.A N ALA 117.A O no hydrogen 2.864 N/A LYS 122.A N GLU 118.A O no hydrogen 2.937 N/A GLY 123.A N LYS 119.A O no hydrogen 2.882 N/A LEU 127.A N ILE 76.A O no hydrogen 2.906 N/A ALA 129.A N VAL 78.A O no hydrogen 2.909 N/A THR 130.A N VAL 107.A O no hydrogen 3.318 N/A ARG 133.A NH1 ALA 111.A O no hydrogen 3.558 N/A ARG 133.A NH2 ALA 111.A O no hydrogen 3.426 N/A HIS 137.A N ARG 133.A O no hydrogen 2.992 N/A HIS 137.A NE2 GLU 116.A OE1 no hydrogen 2.583 N/A LEU 138.A N LEU 134.A O no hydrogen 2.848 N/A GLN 139.A N LEU 135.A O no hydrogen 2.891 N/A THR 141.A N HIS 137.A O no hydrogen 3.213 N/A THR 141.A OG1 HIS 137.A O no hydrogen 2.291 N/A ILE 153.A N ILE 77.A O no hydrogen 2.912 N/A ILE 154.A N MET 184.A O no hydrogen 2.916 N/A ASP 155.A N ILE 79.A O no hydrogen 2.951 N/A GLU 156.A N PHE 186.A O no hydrogen 2.418 N/A ASP 158.A N SER 187.A OG no hydrogen 3.352 N/A ARG 159.A N GLU 156.A O no hydrogen 2.752 N/A ARG 159.A NH1 ASP 316.A OD1 no hydrogen 2.827 N/A ARG 159.A NH2 ASP 316.A OD1 no hydrogen 2.814 N/A ILE 160.A N GLU 156.A O no hydrogen 3.198 N/A LEU 161.A N ALA 157.A O no hydrogen 2.909 N/A GLU 162.A N ASP 158.A O no hydrogen 2.807 N/A ILE 163.A N ARG 159.A O no hydrogen 2.898 N/A GLY 164.A N ILE 160.A O no hydrogen 2.616 N/A PHE 165.A N ILE 160.A O no hydrogen 2.990 N/A MET 169.A N PHE 165.A O no hydrogen 2.881 N/A ARG 170.A N GLU 166.A O no hydrogen 2.897 N/A GLN 171.A N ASP 167.A O no hydrogen 2.977 N/A ILE 172.A N GLU 168.A O no hydrogen 2.859 N/A ILE 173.A N MET 169.A O no hydrogen 2.877 N/A LYS 174.A N ARG 170.A O no hydrogen 2.927 N/A ILE 175.A N GLN 171.A O no hydrogen 2.953 N/A LEU 176.A N ILE 172.A O no hydrogen 2.630 N/A ARG 181.A NH2 ASN 178.A OD1 no hydrogen 2.789 N/A SER 183.A N ASP 40.A OD1 no hydrogen 2.182 N/A MET 184.A N LEU 152.A O no hydrogen 2.934 N/A LEU 185.A N VAL 41.A O no hydrogen 2.919 N/A PHE 186.A N ILE 154.A O no hydrogen 2.874 N/A SER 187.A N GLY 43.A O no hydrogen 2.718 N/A SER 187.A OG ASP 158.A OD2 no hydrogen 2.844 N/A SER 187.A OG THR 189.A O no hydrogen 2.671 N/A THR 189.A N ASP 158.A OD2 no hydrogen 2.988 N/A THR 189.A OG1 ASP 158.A OD2 no hydrogen 2.558 N/A GLU 195.A N THR 191.A O no hydrogen 3.120 N/A ASP 196.A N THR 192.A O no hydrogen 2.882 N/A LEU 197.A N LYS 193.A O no hydrogen 3.369 N/A ALA 198.A N VAL 194.A O no hydrogen 2.915 N/A ARG 199.A N GLU 195.A O no hydrogen 2.857 N/A ILE 200.A N ASP 196.A O no hydrogen 3.307 N/A SER 201.A N LEU 197.A O no hydrogen 2.891 N/A SER 201.A OG SER 183.A OG no hydrogen 3.293 N/A SER 201.A OG LEU 197.A O no hydrogen 3.220 N/A SER 201.A OG ALA 198.A O no hydrogen 3.121 N/A LEU 202.A N ALA 198.A O no hydrogen 2.858 N/A ARG 203.A N ASP 40.A OD2 no hydrogen 2.122 N/A GLN 214.A N PRO 359.A O no hydrogen 3.195 N/A GLY 215.A N SER 338.A O no hydrogen 2.483 N/A TYR 216.A N ASN 361.A O no hydrogen 2.975 N/A VAL 217.A N MET 340.A O no hydrogen 2.908 N/A CYS 219.A N LEU 342.A O no hydrogen 2.589 N/A CYS 219.A SG ASP 220.A O no hydrogen 3.242 N/A LEU 227.A N LYS 223.A O no hydrogen 2.863 N/A LEU 228.A N ARG 224.A O no hydrogen 2.884 N/A PHE 229.A N PHE 225.A O no hydrogen 2.952 N/A SER 230.A N LEU 226.A O no hydrogen 2.855 N/A SER 230.A OG LEU 226.A O no hydrogen 3.041 N/A PHE 231.A N LEU 227.A O no hydrogen 2.866 N/A LEU 232.A N LEU 228.A O no hydrogen 2.882 N/A LYS 233.A N PHE 229.A O no hydrogen 2.939 N/A ARG 234.A N SER 230.A O no hydrogen 2.966 N/A ASN 235.A N PHE 231.A O no hydrogen 3.011 N/A GLN 236.A N LYS 233.A O no hydrogen 3.227 N/A ILE 240.A N GLY 289.A O no hydrogen 3.090 N/A ILE 241.A N TRP 308.A O no hydrogen 3.470 N/A VAL 242.A N LEU 291.A O no hydrogen 2.785 N/A PHE 243.A N ILE 310.A O no hydrogen 2.850 N/A LEU 244.A N CYS 293.A O no hydrogen 2.484 N/A SER 245.A N ASP 313.A OD2 no hydrogen 2.395 N/A SER 245.A OG ASP 313.A OD2 no hydrogen 3.080 N/A SER 246.A OG SER 397.A OG no hydrogen 2.949 N/A SER 249.A OG SER 246.A OG no hydrogen 2.810 N/A SER 249.A OG TYR 425.A OH no hydrogen 2.718 N/A VAL 250.A N SER 246.A O no hydrogen 3.072 N/A LYS 251.A N CYS 247.A O no hydrogen 2.890 N/A TYR 252.A N ASN 248.A O no hydrogen 2.849 N/A TYR 252.A OH TYR 425.A O no hydrogen 3.158 N/A TYR 253.A N SER 249.A O no hydrogen 2.837 N/A ALA 254.A N VAL 250.A O no hydrogen 2.938 N/A GLU 255.A N LYS 251.A O no hydrogen 2.926 N/A LEU 256.A N TYR 252.A O no hydrogen 2.867 N/A LEU 257.A N TYR 253.A O no hydrogen 2.909 N/A ASN 258.A N ALA 254.A O no hydrogen 2.928 N/A TYR 259.A N GLU 255.A O no hydrogen 2.899 N/A ILE 260.A N LEU 256.A O no hydrogen 2.849 N/A ASP 261.A N ASN 258.A O no hydrogen 3.006 N/A LEU 262.A N LEU 257.A O no hydrogen 3.206 N/A VAL 264.A N ASN 258.A OD1 no hydrogen 3.339 N/A LEU 265.A N ILE 290.A O no hydrogen 2.613 N/A GLU 266.A N GLU 266.A OE1 no hydrogen 2.679 N/A LYS 270.A NZ ASN 248.A OD1 no hydrogen 2.201 N/A GLN 271.A N HIS 268.A O no hydrogen 3.165 N/A LYS 272.A N GLN 271.A OE1 no hydrogen 3.250 N/A ARG 276.A N LYS 272.A O no hydrogen 2.548 N/A THR 277.A N GLN 273.A O no hydrogen 2.832 N/A THR 277.A OG1 GLN 273.A O no hydrogen 2.637 N/A ASN 278.A N GLN 274.A O no hydrogen 2.894 N/A THR 279.A N LYS 275.A O no hydrogen 2.893 N/A THR 279.A OG1 LYS 275.A O no hydrogen 3.199 N/A THR 279.A OG1 ARG 276.A O no hydrogen 2.455 N/A PHE 280.A N ARG 276.A O no hydrogen 2.935 N/A PHE 281.A N THR 277.A O no hydrogen 2.875 N/A GLU 282.A N ASN 278.A O no hydrogen 2.875 N/A PHE 283.A N THR 279.A O no hydrogen 2.911 N/A CYS 284.A N PHE 280.A O no hydrogen 2.904 N/A ASN 285.A N PHE 281.A O no hydrogen 2.920 N/A ALA 286.A N GLU 282.A O no hydrogen 2.873 N/A GLU 287.A N PHE 283.A O no hydrogen 3.365 N/A ARG 288.A N ALA 286.A O no hydrogen 2.818 N/A LEU 291.A N ILE 240.A O no hydrogen 2.967 N/A ILE 292.A N LEU 265.A O no hydrogen 2.761 N/A CYS 293.A N VAL 242.A O no hydrogen 2.948 N/A CYS 293.A SG VAL 242.A O no hydrogen 3.323 N/A CYS 293.A SG THR 294.A O no hydrogen 3.240 N/A THR 294.A OG1 GLU 84.A OE2 no hydrogen 3.063 N/A VAL 296.A N GLU 84.A OE2 no hydrogen 3.061 N/A ALA 297.A N THR 294.A OG1 no hydrogen 3.013 N/A ARG 299.A N ASP 295.A O no hydrogen 2.914 N/A GLY 300.A N VAL 296.A O no hydrogen 2.915 N/A ILE 303.A N ASP 302.A OD1 no hydrogen 2.613 N/A ASP 307.A N LYS 239.A O no hydrogen 3.288 N/A ILE 309.A N LYS 337.A O no hydrogen 2.844 N/A ILE 310.A N ILE 241.A O no hydrogen 3.120 N/A GLN 311.A N LEU 339.A O no hydrogen 2.926 N/A GLN 311.A NE2 ASP 313.A O no hydrogen 3.329 N/A PHE 312.A N PHE 243.A O no hydrogen 3.048 N/A ASP 313.A N PHE 243.A O no hydrogen 3.341 N/A ASP 316.A N ASP 295.A OD2 no hydrogen 3.257 N/A ARG 319.A N ASP 317.A OD1 no hydrogen 3.021 N/A TYR 321.A N ASP 317.A O no hydrogen 2.997 N/A ILE 322.A N PRO 318.A O no hydrogen 2.905 N/A HIS 323.A N ARG 319.A O no hydrogen 2.940 N/A ARG 324.A N ASP 320.A O no hydrogen 2.763 N/A ARG 324.A NE ARG 324.A O no hydrogen 2.931 N/A ARG 324.A NE THR 328.A OG1 no hydrogen 3.087 N/A VAL 325.A N TYR 321.A O no hydrogen 2.929 N/A GLY 326.A N ILE 322.A O no hydrogen 3.418 N/A ARG 327.A N HIS 323.A O no hydrogen 2.945 N/A THR 328.A N ARG 324.A O no hydrogen 2.835 N/A THR 328.A OG1 ARG 324.A O no hydrogen 2.347 N/A ALA 329.A N VAL 325.A O no hydrogen 2.913 N/A ARG 330.A N GLY 326.A O no hydrogen 2.933 N/A GLY 331.A N ARG 327.A O no hydrogen 2.878 N/A THR 332.A N THR 328.A O no hydrogen 3.042 N/A THR 332.A OG1 THR 328.A O no hydrogen 2.444 N/A THR 332.A OG1 GLY 334.A O no hydrogen 3.143 N/A LYS 337.A N ASP 307.A O no hydrogen 3.467 N/A LEU 339.A N ILE 309.A O no hydrogen 2.840 N/A MET 340.A N GLY 215.A O no hydrogen 3.147 N/A PHE 341.A N GLN 311.A O no hydrogen 2.947 N/A LEU 342.A N VAL 217.A O no hydrogen 2.438 N/A THR 343.A N GLU 346.A OE1 no hydrogen 3.115 N/A THR 343.A OG1 GLU 346.A OE2 no hydrogen 3.128 N/A ASN 345.A ND2 LYS 415.A O no hydrogen 3.201 N/A GLU 346.A N THR 343.A O no hydrogen 2.791 N/A PHE 349.A N GLU 346.A O no hydrogen 2.934 N/A TYR 352.A N GLY 348.A O no hydrogen 3.074 N/A LEU 353.A N PHE 349.A O no hydrogen 2.655 N/A LYS 354.A N LEU 350.A O no hydrogen 2.638 N/A ALA 355.A N ARG 351.A O no hydrogen 2.575 N/A SER 356.A N TYR 352.A O no hydrogen 2.862 N/A SER 356.A N LEU 353.A O no hydrogen 2.914 N/A SER 356.A OG LEU 353.A O no hydrogen 2.324 N/A ASN 361.A N GLN 214.A O no hydrogen 2.667 N/A TYR 363.A N TYR 216.A O no hydrogen 3.218 N/A ILE 370.A N ASN 368.A O no hydrogen 2.905 N/A LEU 377.A N VAL 373.A O no hydrogen 2.752 N/A GLU 378.A N GLN 374.A O no hydrogen 2.926 N/A LYS 379.A N SER 375.A O no hydrogen 2.924 N/A LEU 380.A N GLN 376.A O no hydrogen 2.895 N/A ILE 381.A N LEU 377.A O no hydrogen 2.912 N/A LYS 382.A N GLU 378.A O no hydrogen 2.909 N/A SER 383.A N LYS 379.A O no hydrogen 2.918 N/A SER 383.A OG LYS 379.A O no hydrogen 3.400 N/A SER 383.A OG LEU 380.A O no hydrogen 2.406 N/A ASN 384.A N LEU 380.A O no hydrogen 2.755 N/A TYR 386.A N ASN 384.A OD1 no hydrogen 3.035 N/A HIS 388.A N ASN 384.A O no hydrogen 2.826 N/A GLN 389.A N TYR 385.A O no hydrogen 2.901 N/A THR 390.A N TYR 386.A O no hydrogen 2.974 N/A THR 390.A OG1 TYR 386.A O no hydrogen 3.235 N/A THR 390.A OG1 LEU 387.A O no hydrogen 3.008 N/A ALA 391.A N LEU 387.A O no hydrogen 2.861 N/A LYS 392.A N HIS 388.A O no hydrogen 2.967 N/A LYS 392.A NZ HIS 388.A NE2 no hydrogen 3.302 N/A ASP 393.A N GLN 389.A O no hydrogen 2.873 N/A GLY 394.A N THR 390.A O no hydrogen 2.919 N/A TYR 395.A N ALA 391.A O no hydrogen 2.975 N/A ARG 396.A N LYS 392.A O no hydrogen 2.842 N/A SER 397.A N ASP 393.A O no hydrogen 2.893 N/A SER 397.A OG SER 246.A OG no hydrogen 2.949 N/A SER 397.A OG ASP 393.A O no hydrogen 2.887 N/A SER 397.A OG GLY 394.A O no hydrogen 3.200 N/A TYR 398.A N GLY 394.A O no hydrogen 2.900 N/A LEU 399.A N TYR 395.A O no hydrogen 2.992 N/A GLN 400.A N ARG 396.A O no hydrogen 2.941 N/A ALA 401.A N SER 397.A O no hydrogen 2.853 N/A TYR 402.A N TYR 398.A O no hydrogen 3.033 N/A TYR 402.A OH TYR 398.A OH no hydrogen 3.201 N/A ALA 403.A N LEU 399.A O no hydrogen 2.918 N/A SER 404.A N GLN 400.A O no hydrogen 2.905 N/A SER 404.A OG GLN 400.A O no hydrogen 3.207 N/A SER 404.A OG ALA 401.A O no hydrogen 2.948 N/A HIS 405.A N TYR 402.A O no hydrogen 3.156 N/A VAL 410.A N LEU 407.A O no hydrogen 3.260 N/A TYR 411.A N LEU 407.A O no hydrogen 2.963 N/A LYS 415.A N GLN 412.A O no hydrogen 3.186 N/A LEU 416.A N ILE 413.A O no hydrogen 3.112 N/A VAL 421.A N ASP 417.A O no hydrogen 3.208 N/A ALA 422.A N LEU 418.A O no hydrogen 2.888 N/A LYS 423.A N ALA 419.A O no hydrogen 2.931 N/A SER 424.A N LYS 420.A O no hydrogen 2.838 N/A SER 424.A OG VAL 421.A O no hydrogen 2.284 N/A TYR 425.A N VAL 421.A O no hydrogen 2.933 N/A TYR 425.A OH SER 249.A OG no hydrogen 2.718 N/A PHE 427.A N ALA 422.A O no hydrogen 2.401 N/A