Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6c9f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 4.A NZ GLU 28.A OE1 no hydrogen 3.175 N/A ILE 5.A N TYR 8.A O no hydrogen 2.904 N/A HIS 7.A ND1 GLU 28.A OE2 no hydrogen 2.632 N/A TYR 8.A N ILE 5.A O no hydrogen 3.020 N/A TYR 8.A OH HIS 32.A ND1 no hydrogen 2.726 N/A ILE 9.A N LYS 26.A O no hydrogen 2.689 N/A LEU 10.A N VAL 3.A O no hydrogen 2.872 N/A GLY 11.A N VAL 24.A O no hydrogen 2.658 N/A LEU 14.A N VAL 22.A O no hydrogen 2.687 N/A GLY 15.A N VAL 22.A O no hydrogen 3.279 N/A VAL 22.A N GLY 15.A O no hydrogen 2.833 N/A LYS 23.A N VAL 36.A O no hydrogen 2.762 N/A LYS 23.A NZ THR 13.A OG1 no hydrogen 2.730 N/A VAL 24.A N ASP 12.A O no hydrogen 2.989 N/A GLY 25.A N VAL 34.A O no hydrogen 2.825 N/A LYS 26.A N ILE 9.A O no hydrogen 2.926 N/A HIS 27.A N HIS 32.A O no hydrogen 2.877 N/A GLU 28.A N HIS 7.A O no hydrogen 3.218 N/A LEU 29.A N HIS 27.A ND1 no hydrogen 3.204 N/A THR 30.A N HIS 27.A ND1 no hydrogen 3.150 N/A GLY 31.A N HIS 27.A O no hydrogen 3.065 N/A HIS 32.A N THR 30.A OG1 no hydrogen 3.098 N/A HIS 32.A ND1 TYR 8.A OH no hydrogen 2.726 N/A VAL 34.A N GLY 25.A O no hydrogen 2.989 N/A ALA 35.A N MET 85.A O no hydrogen 3.069 N/A VAL 36.A N LYS 23.A O no hydrogen 2.677 N/A LYS 37.A N MET 83.A O no hydrogen 2.823 N/A ILE 38.A N LYS 21.A O no hydrogen 2.903 N/A LEU 39.A N ILE 81.A O no hydrogen 2.635 N/A ASN 40.A ND2 ASP 80.A OD1 no hydrogen 3.152 N/A ARG 41.A N SER 79.A O no hydrogen 3.178 N/A ARG 41.A NH1 THR 77.A O no hydrogen 2.397 N/A LYS 43.A N ASN 40.A O no hydrogen 3.109 N/A LYS 43.A N ASN 40.A OD1 no hydrogen 2.883 N/A ILE 44.A N ASN 40.A O no hydrogen 3.081 N/A ARG 45.A N ARG 41.A O no hydrogen 3.235 N/A SER 46.A N GLN 42.A O no hydrogen 3.143 N/A SER 46.A OG GLN 42.A O no hydrogen 2.788 N/A LEU 47.A N LYS 43.A O no hydrogen 3.361 N/A ASP 48.A N ARG 45.A O no hydrogen 3.301 N/A VAL 49.A N ILE 44.A O no hydrogen 3.370 N/A ILE 53.A N VAL 49.A O no hydrogen 3.025 N/A ARG 54.A N VAL 50.A O no hydrogen 2.978 N/A ARG 55.A N GLY 51.A O no hydrogen 2.790 N/A GLU 56.A N LYS 52.A O no hydrogen 2.577 N/A ILE 57.A N ILE 53.A O no hydrogen 3.172 N/A GLN 58.A N ARG 54.A O no hydrogen 3.254 N/A ASN 59.A N ARG 55.A O no hydrogen 3.155 N/A LEU 60.A N GLU 56.A O no hydrogen 2.985 N/A LYS 61.A N ILE 57.A O no hydrogen 3.186 N/A LEU 62.A N ASN 59.A O no hydrogen 3.160 N/A PHE 63.A N LEU 60.A O no hydrogen 3.180 N/A ARG 64.A N TYR 121.A OH no hydrogen 2.938 N/A HIS 67.A N HIS 65.A ND1 no hydrogen 3.051 N/A HIS 67.A ND1 ALA 145.A O no hydrogen 3.075 N/A HIS 67.A NE2 TYR 266.A OH no hydrogen 3.004 N/A ILE 69.A N ILE 147.A O no hydrogen 2.897 N/A LYS 70.A N GLU 86.A OE2 no hydrogen 2.899 N/A TYR 72.A N VAL 84.A O no hydrogen 2.806 N/A GLN 73.A N VAL 84.A O no hydrogen 3.280 N/A VAL 74.A N GLN 73.A OE1 no hydrogen 3.095 N/A ILE 75.A N PHE 82.A O no hydrogen 2.666 N/A THR 77.A N ASP 80.A O no hydrogen 2.749 N/A THR 77.A OG1 ASP 80.A O no hydrogen 2.497 N/A SER 79.A OG ASP 80.A OD2 no hydrogen 2.641 N/A ASP 80.A N THR 77.A OG1 no hydrogen 2.897 N/A ILE 81.A N LEU 39.A O no hydrogen 2.695 N/A PHE 82.A N ILE 75.A O no hydrogen 2.642 N/A MET 83.A N LYS 37.A O no hydrogen 2.839 N/A VAL 84.A N GLN 73.A O no hydrogen 2.753 N/A MET 85.A N ALA 35.A O no hydrogen 2.928 N/A GLU 86.A N LYS 70.A O no hydrogen 3.165 N/A GLY 90.A N LEU 139.A O no hydrogen 2.827 N/A LEU 93.A N VAL 137.A O no hydrogen 2.779 N/A PHE 94.A N PRO 134.A O no hydrogen 3.171 N/A TYR 96.A N GLU 92.A O no hydrogen 3.309 N/A ILE 97.A N LEU 93.A O no hydrogen 3.046 N/A CYS 98.A N PHE 94.A O no hydrogen 3.065 N/A CYS 98.A SG PHE 94.A O no hydrogen 3.147 N/A LYS 99.A N ASP 95.A O no hydrogen 3.175 N/A ASN 100.A N TYR 96.A O no hydrogen 2.930 N/A ASN 100.A ND2 TYR 96.A O no hydrogen 3.063 N/A GLY 101.A N ILE 97.A O no hydrogen 2.763 N/A LEU 103.A N LEU 198.A O no hydrogen 2.911 N/A GLU 107.A N ASP 104.A OD1 no hydrogen 2.932 N/A SER 108.A N ASP 104.A O no hydrogen 2.943 N/A SER 108.A OG LEU 103.A O no hydrogen 3.054 N/A SER 108.A OG ASP 104.A O no hydrogen 3.055 N/A SER 108.A OG LEU 198.A O no hydrogen 3.403 N/A ARG 109.A N GLU 105.A O no hydrogen 3.211 N/A ARG 109.A NH1 TRP 258.A O no hydrogen 3.525 N/A ARG 110.A N LYS 106.A O no hydrogen 3.084 N/A ARG 110.A NH1 MET 143.A O no hydrogen 2.580 N/A ARG 110.A NH2 MET 143.A O no hydrogen 3.269 N/A LEU 111.A N GLU 107.A O no hydrogen 3.090 N/A PHE 112.A N SER 108.A O no hydrogen 2.987 N/A GLN 113.A N ARG 109.A O no hydrogen 2.874 N/A GLN 113.A NE2 PHE 259.A O no hydrogen 2.787 N/A GLN 113.A NE2 GLN 261.A O no hydrogen 3.017 N/A GLN 114.A N ARG 110.A O no hydrogen 3.325 N/A GLN 114.A NE2 ASN 144.A OD1 no hydrogen 3.201 N/A ILE 115.A N LEU 111.A O no hydrogen 2.867 N/A LEU 116.A N PHE 112.A O no hydrogen 2.980 N/A SER 117.A N GLN 113.A O no hydrogen 3.016 N/A SER 117.A OG HIS 65.A NE2 no hydrogen 3.131 N/A SER 117.A OG LEU 267.A O no hydrogen 2.835 N/A GLY 118.A N GLN 114.A O no hydrogen 3.273 N/A VAL 119.A N ILE 115.A O no hydrogen 2.976 N/A ASP 120.A N LEU 116.A O no hydrogen 2.922 N/A TYR 121.A N SER 117.A O no hydrogen 3.133 N/A CYS 122.A N GLY 118.A O no hydrogen 3.083 N/A CYS 122.A SG GLY 118.A O no hydrogen 3.384 N/A HIS 123.A N VAL 119.A O no hydrogen 3.179 N/A HIS 123.A NE2 ASP 187.A OD2 no hydrogen 3.020 N/A ARG 124.A N ASP 120.A O no hydrogen 2.898 N/A HIS 125.A N TYR 121.A O no hydrogen 3.351 N/A HIS 125.A N CYS 122.A O no hydrogen 2.980 N/A HIS 125.A ND1 TYR 121.A O no hydrogen 2.695 N/A MET 126.A N HIS 123.A O no hydrogen 3.162 N/A VAL 127.A N CYS 122.A O no hydrogen 2.861 N/A VAL 128.A N ASN 154.A O no hydrogen 2.771 N/A ARG 130.A N ASP 187.A OD1 no hydrogen 2.768 N/A ARG 130.A NE LEU 152.A O no hydrogen 2.777 N/A ASP 131.A N HIS 129.A ND1 no hydrogen 3.003 N/A GLU 135.A N GLU 135.A OE1 no hydrogen 2.576 N/A ASN 136.A N LYS 133.A O no hydrogen 2.752 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.962 N/A VAL 137.A N PRO 134.A O no hydrogen 3.350 N/A LEU 138.A N LYS 146.A O no hydrogen 2.674 N/A LEU 139.A N GLY 91.A O no hydrogen 3.026 N/A ASP 140.A N ASN 144.A O no hydrogen 3.344 N/A MET 143.A N ASP 140.A O no hydrogen 3.049 N/A ASN 144.A N ASP 140.A OD1 no hydrogen 2.561 N/A ASN 144.A ND2 ASP 140.A OD2 no hydrogen 3.039 N/A ALA 145.A N GLN 114.A OE1 no hydrogen 3.026 N/A LYS 146.A N LEU 138.A O no hydrogen 2.855 N/A LYS 146.A NZ PRO 66.A O no hydrogen 2.646 N/A LYS 146.A NZ GLU 86.A OE1 no hydrogen 3.529 N/A ILE 147.A N HIS 67.A O no hydrogen 2.793 N/A ALA 148.A N ASN 136.A O no hydrogen 3.058 N/A GLY 151.A N ASP 149.A OD1 no hydrogen 3.056 N/A SER 153.A N PHE 150.A O no hydrogen 2.859 N/A SER 153.A OG PHE 150.A O no hydrogen 2.441 N/A ASN 154.A N VAL 128.A O no hydrogen 2.828 N/A MET 156.A N MET 126.A O no hydrogen 2.883 N/A GLU 160.A N SER 157.A O no hydrogen 3.108 N/A LEU 162.A N TYR 181.A O no hydrogen 2.861 N/A SER 164.A OG VAL 175.A O no hydrogen 3.061 N/A CYS 165.A SG LEU 152.A O no hydrogen 3.910 N/A SER 167.A OG ASN 169.A OD1 no hydrogen 3.444 N/A ASN 169.A ND2 PHE 205.A O no hydrogen 2.931 N/A ASN 169.A ND2 ASP 206.A OD1 no hydrogen 3.158 N/A TYR 170.A N SER 167.A O no hydrogen 3.121 N/A ALA 171.A N PRO 168.A O no hydrogen 3.357 N/A GLU 174.A N GLU 174.A OE1 no hydrogen 2.762 N/A VAL 175.A N ALA 172.A O no hydrogen 2.806 N/A ILE 176.A N ALA 172.A O no hydrogen 3.168 N/A SER 177.A N PRO 173.A O no hydrogen 3.214 N/A SER 177.A OG PRO 173.A O no hydrogen 2.613 N/A GLY 178.A N VAL 175.A O no hydrogen 3.006 N/A ARG 179.A N GLU 174.A O no hydrogen 2.945 N/A TYR 181.A N LEU 162.A O no hydrogen 3.415 N/A ALA 182.A N GLU 185.A OE2 no hydrogen 2.985 N/A GLY 183.A N GLU 185.A OE1 no hydrogen 2.740 N/A GLY 183.A N GLU 185.A OE2 no hydrogen 3.496 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.560 N/A ILE 188.A N PRO 184.A O no hydrogen 3.351 N/A TRP 189.A N GLU 185.A O no hydrogen 3.473 N/A SER 190.A N VAL 186.A O no hydrogen 3.349 N/A SER 190.A OG TYR 170.A O no hydrogen 2.724 N/A SER 190.A OG VAL 186.A O no hydrogen 3.316 N/A SER 191.A N ASP 187.A O no hydrogen 3.023 N/A SER 191.A OG ASP 187.A O no hydrogen 2.662 N/A GLY 192.A N ILE 188.A O no hydrogen 2.914 N/A GLY 192.A N TRP 189.A O no hydrogen 3.072 N/A VAL 193.A N TRP 189.A O no hydrogen 3.154 N/A ILE 194.A N SER 190.A O no hydrogen 2.965 N/A LEU 195.A N SER 191.A O no hydrogen 2.992 N/A TYR 196.A N GLY 192.A O no hydrogen 2.979 N/A TYR 196.A OH TYR 223.A O no hydrogen 2.467 N/A ALA 197.A N VAL 193.A O no hydrogen 2.835 N/A LEU 198.A N ILE 194.A O no hydrogen 2.895 N/A LEU 199.A N LEU 195.A O no hydrogen 3.106 N/A CYS 200.A N TYR 196.A O no hydrogen 2.771 N/A CYS 200.A SG TYR 196.A O no hydrogen 3.723 N/A GLY 201.A N ALA 197.A O no hydrogen 2.927 N/A HIS 209.A N ASP 207.A OD1 no hydrogen 2.851 N/A HIS 209.A ND1 THR 212.A OG1 no hydrogen 2.659 N/A THR 212.A OG1 HIS 209.A ND1 no hydrogen 2.659 N/A LEU 213.A N HIS 209.A O no hydrogen 2.939 N/A PHE 214.A N VAL 210.A O no hydrogen 3.024 N/A LYS 215.A N PRO 211.A O no hydrogen 3.222 N/A LYS 215.A NZ ASP 219.A OD2 no hydrogen 2.822 N/A LYS 216.A N THR 212.A O no hydrogen 3.008 N/A LYS 216.A NZ ASP 206.A O no hydrogen 3.425 N/A LYS 216.A NZ ASP 207.A OD2 no hydrogen 2.789 N/A ILE 217.A N LEU 213.A O no hydrogen 3.049 N/A CYS 218.A N PHE 214.A O no hydrogen 3.192 N/A CYS 218.A SG SER 177.A OG no hydrogen 3.714 N/A CYS 218.A SG PHE 214.A O no hydrogen 3.230 N/A ASP 219.A N LYS 215.A O no hydrogen 2.828 N/A GLY 220.A N LYS 216.A O no hydrogen 2.980 N/A GLY 220.A N ILE 217.A O no hydrogen 3.090 N/A LEU 228.A N PRO 225.A O no hydrogen 3.241 N/A ASN 229.A ND2 GLU 105.A OE2 no hydrogen 2.757 N/A SER 231.A N ASN 229.A OD1 no hydrogen 2.935 N/A VAL 232.A N ASN 229.A O no hydrogen 3.020 N/A ILE 233.A N ASN 229.A O no hydrogen 3.105 N/A SER 234.A N PRO 230.A O no hydrogen 3.291 N/A SER 234.A OG SER 231.A O no hydrogen 2.312 N/A SER 234.A OG HIS 256.A NE2 no hydrogen 2.939 N/A LEU 235.A N SER 231.A O no hydrogen 3.426 N/A LEU 236.A N VAL 232.A O no hydrogen 2.894 N/A LYS 237.A N ILE 233.A O no hydrogen 2.826 N/A HIS 238.A N SER 234.A O no hydrogen 3.145 N/A HIS 238.A N LEU 235.A O no hydrogen 3.152 N/A MET 239.A N LEU 235.A O no hydrogen 2.968 N/A LEU 240.A N LEU 236.A O no hydrogen 2.876 N/A GLN 241.A NE2 LYS 237.A O no hydrogen 3.217 N/A MET 245.A N ASP 243.A OD1 no hydrogen 3.027 N/A LYS 246.A N ASP 243.A O no hydrogen 3.084 N/A ARG 247.A N PRO 244.A O no hydrogen 3.344 N/A ARG 247.A NE GLN 241.A O no hydrogen 2.862 N/A ARG 247.A NH1 GLU 174.A OE2 no hydrogen 2.589 N/A ARG 247.A NH1 GLU 185.A O no hydrogen 2.933 N/A ARG 247.A NH2 GLU 174.A OE1 no hydrogen 3.046 N/A ARG 247.A NH2 GLU 174.A OE2 no hydrogen 3.432 N/A ARG 247.A NH2 GLN 241.A O no hydrogen 2.949 N/A ALA 248.A N HIS 238.A O no hydrogen 3.026 N/A THR 249.A N ASP 252.A OD2 no hydrogen 3.173 N/A THR 249.A OG1 ASP 252.A OD2 no hydrogen 3.015 N/A ASP 252.A N THR 249.A OG1 no hydrogen 3.276 N/A ILE 253.A N THR 249.A O no hydrogen 3.040 N/A ARG 254.A N ILE 250.A O no hydrogen 3.026 N/A GLU 255.A N LYS 251.A O no hydrogen 3.135 N/A HIS 256.A N ILE 253.A O no hydrogen 3.092 N/A HIS 256.A NE2 SER 234.A OG no hydrogen 2.939 N/A TRP 258.A N HIS 256.A ND1 no hydrogen 3.036 N/A TRP 258.A NE1 GLU 105.A OE2 no hydrogen 2.620 N/A LYS 260.A N HIS 256.A O no hydrogen 3.130 N/A LEU 263.A N LYS 260.A O no hydrogen 3.325 N/A TYR 266.A OH HIS 67.A NE2 no hydrogen 3.004 N/A ILE 279.A N LEU 340.A O no hydrogen 3.213 N/A SER 281.A N TYR 338.A O no hydrogen 2.904 N/A SER 281.A OG SER 283.A OG no hydrogen 2.359 N/A SER 283.A N SER 281.A OG no hydrogen 3.082 N/A SER 283.A OG SER 281.A OG no hydrogen 2.359 N/A ASP 287.A N ARG 284.A O no hydrogen 2.749 N/A ILE 288.A N ARG 284.A O no hydrogen 2.849 N/A MET 289.A N PRO 285.A O no hydrogen 3.055 N/A ALA 290.A N ASN 286.A O no hydrogen 3.124 N/A GLU 291.A N ASP 287.A O no hydrogen 2.974 N/A VAL 292.A N ILE 288.A O no hydrogen 3.089 N/A CYS 293.A N MET 289.A O no hydrogen 3.503 N/A CYS 293.A SG MET 289.A O no hydrogen 3.107 N/A ARG 294.A N ALA 290.A O no hydrogen 3.329 N/A ALA 295.A N GLU 291.A O no hydrogen 3.144 N/A ILE 296.A N VAL 292.A O no hydrogen 2.749 N/A LYS 297.A N CYS 293.A O no hydrogen 3.235 N/A GLN 298.A N ARG 294.A O no hydrogen 2.941 N/A LEU 299.A N ALA 295.A O no hydrogen 3.203 N/A ASP 300.A N LYS 297.A O no hydrogen 2.704 N/A TYR 301.A N ILE 296.A O no hydrogen 2.950 N/A GLU 302.A N ARG 314.A O no hydrogen 3.409 N/A LYS 304.A N ARG 312.A O no hydrogen 3.128 N/A VAL 306.A N TYR 310.A O no hydrogen 3.309 N/A ASN 307.A N TYR 310.A O no hydrogen 3.191 N/A TYR 309.A N ASN 307.A OD1 no hydrogen 2.672 N/A TYR 310.A N ASN 307.A O no hydrogen 2.956 N/A LEU 311.A N LEU 328.A O no hydrogen 2.715 N/A ARG 312.A N LYS 304.A O no hydrogen 3.176 N/A ARG 312.A NH2 TYR 310.A OH no hydrogen 3.179 N/A VAL 313.A N MET 326.A O no hydrogen 2.831 N/A ARG 314.A N GLU 302.A O no hydrogen 3.063 N/A ARG 315.A N SER 324.A O no hydrogen 2.987 N/A LYS 316.A NZ SER 321.A O no hydrogen 3.456 N/A ASN 317.A N THR 322.A O no hydrogen 3.261 N/A VAL 319.A N ASN 317.A OD1 no hydrogen 3.281 N/A SER 321.A N ASN 317.A O no hydrogen 2.921 N/A SER 324.A N ARG 315.A O no hydrogen 2.817 N/A MET 326.A N VAL 313.A O no hydrogen 2.776 N/A SER 327.A N ARG 343.A O no hydrogen 2.789 N/A LEU 328.A N LEU 311.A O no hydrogen 2.714 N/A GLN 329.A N ASP 341.A O no hydrogen 3.201 N/A GLN 329.A NE2 LEU 330.A O no hydrogen 2.709 N/A LEU 330.A N TYR 309.A O no hydrogen 3.017 N/A TYR 331.A N LEU 339.A O no hydrogen 2.676 N/A GLN 332.A NE2 ASP 334.A O no hydrogen 3.270 N/A VAL 333.A N THR 337.A O no hydrogen 3.120 N/A ASP 334.A N THR 337.A O no hydrogen 3.163 N/A THR 337.A N ASP 334.A O no hydrogen 3.317 N/A TYR 338.A N SER 281.A O no hydrogen 2.842 N/A LEU 339.A N TYR 331.A O no hydrogen 3.068 N/A LEU 340.A N ILE 279.A O no hydrogen 2.849 N/A ASP 341.A N GLN 329.A O no hydrogen 2.744 N/A ARG 343.A N SER 327.A O no hydrogen 3.167 N/A ARG 343.A NH1 GLY 159.A O no hydrogen 2.481 N/A ILE 345.A N LYS 325.A O no hydrogen 3.072 N/A GLU 359.A N SER 355.A O no hydrogen 2.867 N/A PHE 360.A N HIS 356.A O no hydrogen 3.176 N/A PHE 361.A N THR 357.A O no hydrogen 3.140 N/A GLU 362.A N ILE 358.A O no hydrogen 2.791 N/A MET 363.A N GLU 359.A O no hydrogen 3.072 N/A CYS 364.A N PHE 360.A O no hydrogen 3.087 N/A CYS 364.A SG PHE 360.A O no hydrogen 3.215 N/A ALA 365.A N PHE 361.A O no hydrogen 2.683 N/A ASN 366.A N GLU 362.A O no hydrogen 3.231 N/A ASN 366.A ND2 TYR 301.A OH no hydrogen 3.111 N/A ILE 368.A N CYS 364.A O no hydrogen 2.844 N/A LYS 369.A N ALA 365.A O no hydrogen 2.967 N/A ILE 370.A N LEU 367.A O no hydrogen 3.157 N/A LEU 371.A N LEU 367.A O no hydrogen 3.033 N/A ALA 372.A N ILE 368.A O no hydrogen 2.791 N/A