Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6cnh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 171.A OD2 no hydrogen 2.665 N/A SER 1.A OG ASP 171.A OD2 no hydrogen 3.200 N/A MET 2.A N LEU 149.A O no hydrogen 2.686 N/A PHE 4.A N ASN 147.A O no hydrogen 2.864 N/A ALA 8.A N TRP 5.A O no hydrogen 3.014 N/A TYR 12.A OH GLU 18.A OE2 no hydrogen 2.478 N/A ASN 15.A N GLU 18.A OE1 no hydrogen 2.871 N/A GLY 17.A N VAL 26.A O no hydrogen 2.767 N/A GLU 18.A N ASN 15.A O no hydrogen 3.102 N/A LEU 20.A N TYR 24.A O no hydrogen 2.877 N/A ARG 23.A N LEU 20.A O no hydrogen 3.013 N/A ARG 23.A NE ASP 43.A OD1 no hydrogen 3.001 N/A ARG 23.A NH2 ASP 43.A OD1 no hydrogen 3.544 N/A ARG 23.A NH2 ASP 43.A OD2 no hydrogen 2.851 N/A TYR 24.A N LEU 20.A O no hydrogen 2.933 N/A ASN 25.A N ARG 42.A O no hydrogen 2.925 N/A VAL 26.A N GLU 18.A O no hydrogen 3.026 N/A TYR 27.A N ARG 40.A O no hydrogen 3.037 N/A TYR 29.A OH VAL 14.A O no hydrogen 2.888 N/A THR 30.A N VAL 38.A O no hydrogen 3.288 N/A THR 30.A OG1 VAL 38.A O no hydrogen 2.937 N/A GLN 32.A N THR 30.A OG1 no hydrogen 3.063 N/A ASN 37.A ND2.A TYR 12.A O no hydrogen 2.642 N/A VAL 39.A N VAL 53.A O no hydrogen 2.840 N/A ARG 40.A N GLY 28.A O no hydrogen 2.716 N/A ARG 40.A NE GLU 50.A OE1 no hydrogen 3.357 N/A ARG 40.A NH2 GLU 50.A OE1 no hydrogen 3.490 N/A ALA 41.A N VAL 51.A O no hydrogen 3.032 N/A ARG 42.A N ASN 25.A O no hydrogen 3.028 N/A ASP 43.A N GLN 49.A O no hydrogen 2.796 N/A ASN 44.A N ARG 23.A O no hydrogen 2.712 N/A ASN 44.A ND2 ASN 48.A OD1 no hydrogen 2.640 N/A ALA 45.A N ASP 43.A OD1 no hydrogen 3.048 N/A ARG 46.A N ASP 43.A O no hydrogen 3.052 N/A ARG 46.A NH2 ALA 45.A O no hydrogen 3.002 N/A GLN 49.A N ARG 46.A O no hydrogen 3.151 N/A VAL 51.A N ALA 41.A O no hydrogen 2.906 N/A ALA 52.A N PHE 104.A O no hydrogen 3.031 N/A VAL 53.A N VAL 39.A O no hydrogen 2.867 N/A LYS 54.A N LEU 102.A O no hydrogen 2.816 N/A LYS 54.A NZ GLU 69.A OE1 no hydrogen 2.729 N/A LYS 54.A NZ GLU 69.A OE2 no hydrogen 3.230 N/A ILE 55.A N ASN 37.A O no hydrogen 2.836 N/A ILE 56.A N LEU 100.A O no hydrogen 2.974 N/A ARG 57.A NE PHE 35.A O no hydrogen 2.696 N/A ARG 57.A NH1 ALA 8.A O no hydrogen 2.766 N/A ARG 57.A NH2 PHE 35.A O no hydrogen 3.210 N/A ASN 58.A N GLY 10.A O no hydrogen 2.851 N/A ASN 58.A ND2 GLN 98.A OE1 no hydrogen 3.236 N/A ASN 59.A N ARG 57.A O no hydrogen 3.101 N/A ASN 59.A ND2 ASP 7.A O no hydrogen 3.136 N/A ASN 59.A ND2 GLU 9.A O no hydrogen 2.892 N/A MET 62.A N ASN 59.A OD1 no hydrogen 2.970 N/A GLN 63.A N ASN 59.A O no hydrogen 2.953 N/A LYS 64.A N GLU 60.A O no hydrogen 3.075 N/A THR 65.A N LEU 61.A O no hydrogen 2.920 N/A THR 65.A OG1 LEU 61.A O no hydrogen 2.651 N/A GLY 66.A N MET 62.A O no hydrogen 2.811 N/A LEU 67.A N GLN 63.A O no hydrogen 3.027 N/A LYS 68.A N LYS 64.A O no hydrogen 3.034 N/A GLU 69.A N THR 65.A O no hydrogen 2.945 N/A LEU 70.A N GLY 66.A O no hydrogen 2.882 N/A GLU 71.A N LEU 67.A O no hydrogen 2.984 N/A PHE 72.A N LYS 68.A O no hydrogen 2.953 N/A LEU 73.A N GLU 69.A O no hydrogen 3.035 N/A LYS 74.A N LEU 70.A O no hydrogen 2.989 N/A LYS 75.A N GLU 71.A O no hydrogen 3.051 N/A LYS 75.A NZ CYS 146.A O no hydrogen 2.647 N/A LEU 76.A N PHE 72.A O no hydrogen 3.004 N/A ASN 77.A N LEU 73.A O no hydrogen 2.735 N/A ASN 77.A ND2 LEU 90.A O no hydrogen 2.842 N/A ASP 78.A N LYS 74.A O no hydrogen 2.903 N/A ALA 79.A N LYS 75.A O no hydrogen 2.982 N/A ASP 80.A N LEU 76.A O no hydrogen 3.020 N/A ASP 83.A N ASP 80.A O no hydrogen 3.079 N/A LYS 84.A N ASP 80.A OD1 no hydrogen 2.957 N/A PHE 85.A N ASP 80.A OD2 no hydrogen 2.932 N/A HIS 86.A ND1 LEU 167.A O no hydrogen 3.095 N/A CYS 87.A SG PHE 85.A O no hydrogen 3.942 N/A LEU 88.A N LEU 169.A O no hydrogen 3.113 N/A ARG 89.A N GLU 105.A OE1 no hydrogen 2.877 N/A ARG 89.A NH1 ASP 80.A O no hydrogen 2.691 N/A ARG 89.A NH2 ASN 77.A O no hydrogen 3.358 N/A ARG 89.A NH2 ASP 80.A O no hydrogen 3.087 N/A LEU 91.A N VAL 103.A O no hydrogen 2.659 N/A ARG 92.A NH1 ASP 21.A OD2 no hydrogen 2.767 N/A ARG 92.A NH1 TYR 24.A OH no hydrogen 2.918 N/A ARG 92.A NH2 ASP 21.A OD2 no hydrogen 3.174 N/A PHE 94.A N CYS 101.A O no hydrogen 2.983 N/A HIS 96.A N HIS 99.A O no hydrogen 2.967 N/A LYS 97.A NZ TYR 12.A OH no hydrogen 3.015 N/A HIS 99.A N HIS 96.A O no hydrogen 2.980 N/A HIS 99.A ND1 ILE 56.A O no hydrogen 2.906 N/A CYS 101.A N PHE 94.A O no hydrogen 2.745 N/A CYS 101.A SG HIS 99.A O no hydrogen 3.619 N/A LEU 102.A N LYS 54.A O no hydrogen 2.956 N/A VAL 103.A N ARG 92.A O no hydrogen 2.917 N/A PHE 104.A N ALA 52.A O no hydrogen 2.785 N/A GLU 105.A N ARG 89.A O no hydrogen 3.106 N/A SER 108.A N VAL 160.A O no hydrogen 2.816 N/A MET 109.A N VAL 160.A O no hydrogen 3.403 N/A ASN 110.A N GLU 113.A OE1 no hydrogen 3.332 N/A ASN 110.A ND2 ASP 156.A O no hydrogen 3.279 N/A LEU 111.A N PRO 155.A O no hydrogen 3.165 N/A LEU 111.A N ILE 158.A O no hydrogen 2.833 N/A ARG 112.A NE ASP 156.A OD1 no hydrogen 3.346 N/A ARG 112.A NE ASP 156.A OD2 no hydrogen 2.956 N/A ARG 112.A NH1 GLU 204.A OE2 no hydrogen 2.583 N/A ARG 112.A NH2 ASP 156.A OD1 no hydrogen 2.760 N/A ARG 112.A NH2 TYR 178.A OH no hydrogen 2.898 N/A GLU 113.A N ASN 110.A OD1 no hydrogen 2.755 N/A VAL 114.A N ASN 110.A O no hydrogen 3.165 N/A LEU 115.A N LEU 111.A O no hydrogen 2.983 N/A LYS 116.A N ARG 112.A O no hydrogen 2.968 N/A LYS 117.A N GLU 113.A O no hydrogen 3.050 N/A TYR 118.A N VAL 114.A O no hydrogen 3.196 N/A GLY 119.A N LEU 115.A O no hydrogen 3.321 N/A GLY 119.A N LYS 116.A O no hydrogen 2.880 N/A VAL 122.A N GLY 119.A O no hydrogen 3.289 N/A LEU 124.A N LEU 205.A O no hydrogen 2.750 N/A LYS 127.A N HIS 125.A ND1 no hydrogen 3.165 N/A VAL 129.A N HIS 125.A O no hydrogen 3.089 N/A ARG 130.A N ILE 126.A O no hydrogen 2.847 N/A ARG 130.A NH2 ILE 319.A O no hydrogen 3.412 N/A SER 131.A N LYS 127.A O no hydrogen 3.145 N/A TYR 132.A N ALA 128.A O no hydrogen 2.901 N/A TYR 132.A OH LYS 164.A O no hydrogen 2.565 N/A SER 133.A N VAL 129.A O no hydrogen 2.847 N/A SER 133.A OG ARG 130.A O no hydrogen 2.713 N/A GLN 134.A N ARG 130.A O no hydrogen 3.198 N/A GLN 135.A N SER 131.A O no hydrogen 3.154 N/A GLN 135.A NE2 SER 131.A O no hydrogen 3.491 N/A GLN 135.A NE2 SER 131.A OG no hydrogen 2.975 N/A GLN 135.A NE2 THR 165.A O no hydrogen 2.988 N/A LEU 136.A N TYR 132.A O no hydrogen 2.948 N/A PHE 137.A N SER 133.A O no hydrogen 2.991 N/A LEU 138.A N GLN 134.A O no hydrogen 3.016 N/A ALA 139.A N GLN 135.A O no hydrogen 2.989 N/A LEU 140.A N LEU 136.A O no hydrogen 2.887 N/A LYS 141.A N PHE 137.A O no hydrogen 2.887 N/A LYS 141.A NZ ASN 311.A OD1 no hydrogen 2.683 N/A LEU 142.A N LEU 138.A O no hydrogen 3.113 N/A LEU 143.A N ALA 139.A O no hydrogen 3.009 N/A LYS 144.A N LEU 140.A O no hydrogen 3.020 N/A ARG 145.A N LYS 141.A O no hydrogen 3.014 N/A CYS 146.A N LEU 142.A O no hydrogen 2.904 N/A CYS 146.A SG LEU 142.A O no hydrogen 3.472 N/A ASN 147.A N LYS 144.A O no hydrogen 3.082 N/A ILE 148.A N LEU 143.A O no hydrogen 2.869 N/A LEU 149.A N MET 2.A O no hydrogen 2.798 N/A HIS 150.A N ASP 194.A OD2 no hydrogen 2.815 N/A HIS 150.A NE2 CYS 170.A O.A no hydrogen 2.770 N/A HIS 150.A NE2 CYS 170.A O.B no hydrogen 2.610 N/A ALA 151.A N ASP 194.A OD1 no hydrogen 2.884 N/A ASP 152.A N HIS 150.A ND1 no hydrogen 3.067 N/A LYS 154.A NZ SER 175.A OG no hydrogen 2.976 N/A ASN 157.A N LYS 154.A O no hydrogen 3.005 N/A ASN 157.A ND2 ASP 152.A O no hydrogen 2.665 N/A ASN 157.A ND2 ASP 152.A OD2 no hydrogen 3.288 N/A ILE 158.A N PRO 155.A O no hydrogen 3.214 N/A LEU 159.A N LYS 168.A O no hydrogen 2.935 N/A VAL 160.A N MET 109.A O no hydrogen 2.742 N/A ASN 161.A N ILE 166.A O no hydrogen 3.052 N/A ASN 161.A ND2 THR 165.A OG1 no hydrogen 3.309 N/A SER 163.A OG THR 165.A OG1 no hydrogen 2.902 N/A LYS 164.A N ASN 161.A O no hydrogen 3.046 N/A THR 165.A OG1 SER 163.A OG no hydrogen 2.902 N/A ILE 166.A N ASN 161.A OD1 no hydrogen 3.105 N/A LEU 167.A N GLN 135.A OE1 no hydrogen 2.839 N/A LYS 168.A N LEU 159.A O no hydrogen 2.809 N/A LYS 168.A NZ ASP 83.A OD1 no hydrogen 3.042 N/A LYS 168.A NZ ASP 83.A OD2 no hydrogen 2.729 N/A LYS 168.A NZ CYS 87.A O no hydrogen 3.025 N/A LYS 168.A NZ GLU 105.A OE1 no hydrogen 2.722 N/A LEU 169.A N HIS 86.A O no hydrogen 2.863 N/A CYS 170.A N.A ASN 157.A O no hydrogen 2.890 N/A CYS 170.A N.B ASN 157.A O no hydrogen 2.849 N/A CYS 170.A SG.A ASN 157.A O no hydrogen 3.219 N/A CYS 170.A SG.B LYS 168.A O no hydrogen 3.735 N/A SER 175.A OG ASP 152.A OD1 no hydrogen 2.585 N/A SER 175.A OG ASP 152.A OD2 no hydrogen 3.463 N/A ARG 176.A NE GLY 214.A O no hydrogen 2.749 N/A ARG 176.A NH2 GLY 214.A O no hydrogen 2.894 N/A PHE 177.A N PHE 174.A O no hydrogen 3.074 N/A TYR 178.A N SER 175.A O no hydrogen 3.192 N/A TYR 178.A OH GLU 204.A OE1 no hydrogen 2.507 N/A TYR 178.A OH GLU 204.A OE2 no hydrogen 3.314 N/A ARG 179.A N ARG 176.A O no hydrogen 3.317 N/A ARG 179.A NH2 ASN 217.A OD1 no hydrogen 3.230 N/A GLU 182.A N GLU 182.A OE1 no hydrogen 2.727 N/A ILE 183.A N ALA 180.A O no hydrogen 3.171 N/A ILE 184.A N ALA 180.A O no hydrogen 3.357 N/A ILE 185.A N PRO 181.A O no hydrogen 2.981 N/A GLY 186.A N GLU 182.A O no hydrogen 3.135 N/A GLY 186.A N ILE 183.A O no hydrogen 3.241 N/A LYS 187.A N GLU 182.A O no hydrogen 2.824 N/A LYS 187.A NZ SER 188.A O no hydrogen 3.214 N/A GLY 192.A N ASP 190.A OD1 no hydrogen 2.950 N/A ILE 193.A N ASP 190.A O no hydrogen 3.121 N/A ASP 194.A N TYR 191.A O no hydrogen 3.043 N/A TRP 196.A N GLY 192.A O no hydrogen 3.067 N/A SER 197.A N ILE 193.A O no hydrogen 3.178 N/A SER 197.A OG TYR 178.A O no hydrogen 2.760 N/A SER 197.A OG ILE 193.A O no hydrogen 3.089 N/A VAL 198.A N ASP 194.A O no hydrogen 3.016 N/A GLY 199.A N MET 195.A O no hydrogen 2.970 N/A CYS 200.A N TRP 196.A O no hydrogen 3.084 N/A CYS 200.A SG PHE 177.A O no hydrogen 4.032 N/A CYS 200.A SG TRP 196.A O no hydrogen 3.602 N/A THR 201.A N SER 197.A O no hydrogen 2.941 N/A THR 201.A OG1 SER 197.A O no hydrogen 2.834 N/A LEU 202.A N VAL 198.A O no hydrogen 2.885 N/A TYR 203.A N GLY 199.A O no hydrogen 3.190 N/A GLU 204.A N CYS 200.A O no hydrogen 3.267 N/A LEU 205.A N THR 201.A O no hydrogen 2.816 N/A TYR 206.A N LEU 202.A O no hydrogen 3.160 N/A THR 207.A N TYR 203.A O no hydrogen 2.969 N/A THR 207.A OG1 TYR 203.A O no hydrogen 2.966 N/A GLY 208.A N GLU 204.A O no hydrogen 2.713 N/A LYS 209.A N THR 207.A OG1 no hydrogen 2.957 N/A LYS 209.A NZ.A ASP 121.A OD2 no hydrogen 3.207 N/A GLY 214.A N PHE 212.A O no hydrogen 2.910 N/A LYS 215.A N HIS 219.A ND1 no hydrogen 3.171 N/A ASN 218.A ND2 HIS 245.A ND1 no hydrogen 3.066 N/A ASN 218.A ND2 MET 253.A O no hydrogen 2.940 N/A HIS 219.A N THR 216.A OG1 no hydrogen 3.048 N/A MET 220.A N THR 216.A O no hydrogen 2.966 N/A LEU 221.A N ASN 217.A O no hydrogen 3.133 N/A LYS 222.A N ASN 218.A O no hydrogen 3.132 N/A LYS 222.A NZ ASP 226.A OD1 no hydrogen 2.849 N/A LEU 223.A N HIS 219.A O no hydrogen 2.957 N/A ALA 224.A N MET 220.A O no hydrogen 3.011 N/A MET 225.A N LEU 221.A O no hydrogen 2.922 N/A ASP 226.A N LYS 222.A O no hydrogen 2.730 N/A LEU 227.A N ALA 224.A O no hydrogen 3.037 N/A LYS 228.A N ALA 224.A O no hydrogen 3.051 N/A LYS 228.A NZ ASP 297.A O no hydrogen 2.749 N/A GLY 229.A N MET 225.A O no hydrogen 2.720 N/A LYS 230.A NZ LEU 250.A O no hydrogen 2.629 N/A ILE 236.A N PRO 232.A O no hydrogen 3.093 N/A ARG 237.A N ASN 233.A O no hydrogen 3.055 N/A LYS 238.A N MET 235.A O no hydrogen 3.238 N/A GLY 239.A N ILE 236.A O no hydrogen 3.096 N/A VAL 240.A N GLY 186.A O no hydrogen 2.930 N/A PHE 241.A N ILE 185.A O no hydrogen 2.840 N/A LYS 242.A N GLY 239.A O no hydrogen 3.221 N/A GLN 244.A N PHE 241.A O no hydrogen 3.157 N/A HIS 245.A N LYS 242.A O no hydrogen 3.100 N/A PHE 246.A N LYS 242.A O no hydrogen 2.679 N/A ASP 247.A N ASN 251.A O no hydrogen 2.915 N/A LEU 250.A N ASP 247.A O no hydrogen 2.956 N/A ASN 251.A N ASP 247.A OD1 no hydrogen 3.010 N/A ASN 251.A ND2 ASP 247.A OD2 no hydrogen 3.022 N/A PHE 252.A N MET 262.A O no hydrogen 2.841 N/A MET 253.A N HIS 245.A O no hydrogen 2.703 N/A TYR 254.A N THR 260.A O no hydrogen 2.830 N/A ILE 255.A N ASN 218.A OD1 no hydrogen 2.976 N/A GLU 256.A N LYS 258.A O no hydrogen 2.930 N/A LYS 258.A N GLU 256.A O no hydrogen 3.064 N/A THR 260.A N TYR 254.A O no hydrogen 2.855 N/A THR 260.A OG1 GLU 256.A OE2 no hydrogen 3.262 N/A MET 262.A N PHE 252.A O no hydrogen 2.870 N/A THR 268.A N ASP 226.A O no hydrogen 2.823 N/A LYS 269.A N ASP 226.A O no hydrogen 2.961 N/A LYS 269.A NZ ASP 274.A OD2 no hydrogen 3.013 N/A ALA 273.A N ASP 270.A OD1 no hydrogen 3.153 N/A ASP 274.A N ASP 270.A O no hydrogen 3.058 N/A LEU 275.A N LEU 271.A O no hydrogen 2.834 N/A ILE 276.A N LEU 272.A O no hydrogen 2.850 N/A GLY 277.A N ALA 273.A O no hydrogen 2.933 N/A GLN 279.A N ILE 276.A O no hydrogen 3.384 N/A GLN 279.A NE2 TYR 206.A OH no hydrogen 3.084 N/A GLN 279.A NE2 ILE 276.A O no hydrogen 2.761 N/A ARG 286.A N PRO 282.A O no hydrogen 2.910 N/A LYS 287.A N GLU 283.A O no hydrogen 2.991 N/A LYS 288.A N ASP 284.A O no hydrogen 3.314 N/A LYS 288.A NZ GLN 291.A OE1 no hydrogen 2.796 N/A LYS 288.A NZ PHE 318.A O no hydrogen 2.655 N/A LYS 288.A NZ GLU 321.A O no hydrogen 2.769 N/A VAL 289.A N GLN 285.A O no hydrogen 3.009 N/A HIS 290.A N ARG 286.A O no hydrogen 3.145 N/A HIS 290.A ND1 ARG 286.A O no hydrogen 2.742 N/A GLN 291.A N LYS 287.A O no hydrogen 3.053 N/A LEU 292.A N LYS 288.A O no hydrogen 2.905 N/A LYS 293.A N VAL 289.A O no hydrogen 2.893 N/A LYS 293.A NZ ASP 297.A OD2 no hydrogen 2.625 N/A ASP 294.A N HIS 290.A O no hydrogen 2.984 N/A LEU 295.A N GLN 291.A O no hydrogen 2.912 N/A LEU 296.A N LEU 292.A O no hydrogen 2.925 N/A ASP 297.A N LYS 293.A O no hydrogen 2.942 N/A GLN 298.A N ASP 294.A O no hydrogen 3.106 N/A ILE 299.A N LEU 295.A O no hydrogen 2.927 N/A LEU 300.A N LEU 296.A O no hydrogen 2.866 N/A ALA 305.A N ASP 303.A OD1 no hydrogen 3.065 N/A LYS 306.A N ASP 303.A O no hydrogen 2.938 N/A ARG 307.A N PRO 304.A O no hydrogen 3.152 N/A ARG 307.A NE MET 301.A O no hydrogen 2.801 N/A ARG 307.A NH1 GLU 182.A OE1 no hydrogen 3.481 N/A ARG 307.A NH1 GLU 182.A OE2 no hydrogen 2.734 N/A ARG 307.A NH1 GLY 192.A O no hydrogen 2.899 N/A ARG 307.A NH2 GLU 182.A OE1 no hydrogen 2.739 N/A ARG 307.A NH2 MET 301.A O no hydrogen 3.278 N/A ILE 308.A N GLN 298.A O no hydrogen 3.037 N/A GLN 312.A N SER 309.A OG no hydrogen 2.988 N/A ALA 313.A N SER 309.A O no hydrogen 2.931 N/A LEU 314.A N ILE 310.A O no hydrogen 2.949 N/A GLN 315.A N ASN 311.A O no hydrogen 3.094 N/A HIS 316.A N ALA 313.A O no hydrogen 3.165 N/A HIS 316.A NE2 ASP 294.A OD2 no hydrogen 2.755 N/A PHE 318.A N HIS 316.A ND1 no hydrogen 2.969 N/A ILE 319.A N HIS 316.A O no hydrogen 2.993 N/A GLN 320.A N HIS 316.A O no hydrogen 2.865 N/A GLN 320.A NE2 LEU 314.A O no hydrogen 2.960 N/A GLU 321.A N ALA 317.A O no hydrogen 2.861 N/A