Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6co8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 1.A N ASP 42.A OD2 no hydrogen 2.421 N/A ILE 1.A N HIS 144.A NE2 no hydrogen 2.993 N/A CYS 3.A SG ILE 43.A O no hydrogen 3.861 N/A VAL 6.A N CYS 3.A O no hydrogen 3.407 N/A ARG 9.A NH2 THR 321.A OG1 no hydrogen 3.013 N/A ARG 9.A NH2 THR 325.A OG1 no hydrogen 2.626 N/A ASP 10.A N CYS 30.A O no hydrogen 2.649 N/A VAL 12.A N THR 32.A O no hydrogen 2.759 N/A SER 16.A N TRP 20.A O no hydrogen 3.117 N/A GLY 17.A N MET 15.A O no hydrogen 2.809 N/A THR 19.A N SER 16.A O no hydrogen 3.343 N/A THR 19.A OG1 SER 16.A O no hydrogen 2.403 N/A VAL 21.A N LEU 293.A O no hydrogen 3.331 N/A ASP 22.A N SER 433.A O no hydrogen 3.344 N/A VAL 23.A N CYS 291.A O no hydrogen 2.562 N/A GLU 26.A N GLU 26.A OE1 no hydrogen 2.874 N/A CYS 30.A N ASN 8.A O no hydrogen 3.089 N/A VAL 31.A N ILE 43.A O no hydrogen 2.921 N/A THR 32.A N ASP 10.A O no hydrogen 2.513 N/A THR 32.A OG1 ASP 42.A OD1 no hydrogen 2.599 N/A VAL 33.A N VAL 41.A O no hydrogen 2.900 N/A MET 34.A N VAL 12.A O no hydrogen 2.998 N/A THR 40.A OG1 ILE 359.A O no hydrogen 2.428 N/A VAL 41.A N VAL 33.A O no hydrogen 3.040 N/A ASP 42.A N SER 142.A O no hydrogen 2.888 N/A ILE 43.A N VAL 31.A O no hydrogen 2.706 N/A GLU 44.A N MET 140.A O no hydrogen 2.970 N/A VAL 46.A N ARG 138.A O no hydrogen 3.104 N/A THR 48.A OG1 HIS 27.A NE2 no hydrogen 3.355 N/A THR 49.A N GLU 136.A O no hydrogen 3.287 N/A THR 49.A OG1 GLU 136.A OE1 no hydrogen 2.751 N/A VAL 50.A N GLY 282.A O no hydrogen 3.017 N/A SER 51.A N ASN 134.A O no hydrogen 3.293 N/A SER 51.A OG THR 49.A O no hydrogen 3.417 N/A SER 51.A OG GLU 136.A OE2 no hydrogen 2.995 N/A GLU 55.A N GLU 55.A OE1 no hydrogen 2.778 N/A VAL 56.A N GLY 127.A O no hydrogen 2.741 N/A SER 58.A N HIS 226.A O no hydrogen 3.198 N/A TYR 59.A OH PHE 218.A O no hydrogen 2.571 N/A CYS 60.A N PRO 224.A O no hydrogen 2.556 N/A CYS 60.A SG LYS 123.A O no hydrogen 3.737 N/A TYR 61.A N LYS 123.A O no hydrogen 3.236 N/A GLU 62.A N LYS 123.A O no hydrogen 3.226 N/A SER 66.A N LYS 118.A O no hydrogen 2.938 N/A ASP 67.A N SER 66.A OG no hydrogen 2.594 N/A ALA 69.A N CYS 116.A O no hydrogen 3.242 N/A SER 70.A OG VAL 114.A O no hydrogen 2.562 N/A SER 70.A OG THR 115.A OG1 no hydrogen 2.722 N/A ASP 71.A N VAL 114.A O no hydrogen 2.867 N/A ARG 73.A N SER 112.A O no hydrogen 3.060 N/A THR 76.A OG1 PRO 75.A O no hydrogen 2.607 N/A ALA 80.A N SER 112.A OG no hydrogen 3.281 N/A GLN 85.A N LEU 82.A O no hydrogen 3.171 N/A SER 86.A OG ASP 83.A O no hydrogen 2.578 N/A GLN 89.A N ASP 87.A OD1 no hydrogen 3.316 N/A VAL 91.A N ALA 117.A O no hydrogen 2.727 N/A LYS 93.A N THR 115.A O no hydrogen 3.238 N/A THR 95.A N LEU 113.A O no hydrogen 2.631 N/A VAL 97.A N GLY 111.A O no hydrogen 2.714 N/A ARG 99.A N GLY 109.A O no hydrogen 3.095 N/A ARG 99.A NE ASN 103.A O no hydrogen 3.615 N/A ASN 103.A N GLY 100.A O no hydrogen 3.171 N/A CYS 105.A N GLY 100.A O no hydrogen 3.259 N/A CYS 105.A SG LEU 107.A O no hydrogen 3.303 N/A GLY 109.A N ARG 99.A O no hydrogen 3.134 N/A LYS 110.A NZ ASP 98.A OD1 no hydrogen 2.779 N/A SER 112.A OG THR 95.A O no hydrogen 3.548 N/A VAL 114.A N ASP 71.A O no hydrogen 2.729 N/A THR 115.A N LYS 93.A O no hydrogen 3.137 N/A THR 115.A OG1 SER 70.A OG no hydrogen 2.722 N/A CYS 116.A N ALA 69.A O no hydrogen 2.951 N/A ALA 117.A N VAL 91.A O no hydrogen 2.803 N/A PHE 119.A N GLN 89.A O no hydrogen 2.848 N/A ALA 120.A N SER 64.A O no hydrogen 3.206 N/A CYS 121.A SG GLU 62.A O no hydrogen 3.642 N/A CYS 121.A SG LYS 123.A O no hydrogen 3.305 N/A SER 122.A N GLU 62.A O no hydrogen 3.126 N/A SER 122.A OG GLU 62.A O no hydrogen 2.768 N/A LYS 123.A N GLU 62.A O no hydrogen 3.260 N/A LYS 124.A NZ SER 58.A OG no hydrogen 3.304 N/A LYS 124.A NZ THR 126.A OG1 no hydrogen 3.097 N/A MET 125.A N TYR 59.A O no hydrogen 2.790 N/A THR 126.A N THR 205.A O no hydrogen 3.089 N/A LYS 128.A N TYR 203.A O no hydrogen 3.056 N/A SER 129.A N ALA 54.A O no hydrogen 2.884 N/A ASN 134.A N GLN 131.A O no hydrogen 3.316 N/A TYR 137.A N ILE 169.A O no hydrogen 3.201 N/A TYR 137.A OH PRO 192.A O no hydrogen 3.310 N/A ARG 138.A N THR 47.A O no hydrogen 3.309 N/A ARG 138.A NE THR 47.A OG1 no hydrogen 2.806 N/A ARG 138.A NH2 THR 47.A OG1 no hydrogen 3.222 N/A ILE 139.A N VAL 167.A O no hydrogen 2.815 N/A MET 140.A N GLU 44.A O no hydrogen 2.809 N/A LEU 141.A N ALA 165.A O no hydrogen 2.956 N/A SER 142.A N ASP 42.A O no hydrogen 3.006 N/A SER 142.A OG ILE 1.A O no hydrogen 3.307 N/A SER 142.A OG GLN 147.A OE1 no hydrogen 3.477 N/A VAL 143.A N ASN 163.A O no hydrogen 3.050 N/A HIS 144.A N THR 40.A O no hydrogen 2.826 N/A HIS 144.A NE2 ASP 42.A OD2 no hydrogen 2.383 N/A SER 146.A OG ASN 163.A OD1 no hydrogen 3.180 N/A GLN 147.A N GLY 145.A O no hydrogen 2.711 N/A SER 149.A OG GLU 329.A OE1 no hydrogen 2.359 N/A GLY 150.A N HIS 148.A ND1 no hydrogen 3.063 N/A MET 151.A N HIS 148.A O no hydrogen 3.340 N/A ASN 154.A ND2 GLY 150.A O no hydrogen 3.478 N/A THR 156.A N ASN 154.A OD1 no hydrogen 3.291 N/A ARG 164.A NE ASP 161.A OD2 no hydrogen 2.414 N/A ALA 165.A N LEU 141.A O no hydrogen 3.365 N/A VAL 167.A N ILE 139.A O no hydrogen 3.079 N/A ILE 169.A N TYR 137.A O no hydrogen 2.749 N/A SER 173.A N ASN 172.A OD1 no hydrogen 2.725 N/A ALA 178.A N LEU 186.A O no hydrogen 3.034 N/A SER 185.A OG GLU 177.A OE2 no hydrogen 2.554 N/A GLY 187.A N LYS 294.A O no hydrogen 2.965 N/A LEU 188.A N ALA 176.A O no hydrogen 2.921 N/A ASP 200.A N ASP 197.A O no hydrogen 2.933 N/A TYR 202.A N VAL 213.A O no hydrogen 2.443 N/A TYR 202.A OH HIS 219.A NE2 no hydrogen 2.837 N/A TYR 203.A N LYS 128.A O no hydrogen 2.873 N/A TYR 203.A OH GLU 276.A O no hydrogen 2.326 N/A LEU 204.A N TRP 211.A O no hydrogen 2.998 N/A THR 205.A OG1 HIS 210.A ND1 no hydrogen 3.197 N/A MET 206.A N LYS 209.A O no hydrogen 2.790 N/A ASN 207.A ND2 GLU 262.A OE2 no hydrogen 3.353 N/A LYS 209.A N MET 206.A O no hydrogen 2.850 N/A HIS 210.A ND1 THR 205.A OG1 no hydrogen 3.197 N/A LEU 212.A N LEU 273.A O no hydrogen 2.646 N/A LYS 215.A N ASP 200.A O no hydrogen 2.792 N/A LYS 215.A NZ ASP 200.A OD1 no hydrogen 2.629 N/A GLU 216.A N HIS 214.A ND1 no hydrogen 3.028 N/A PHE 218.A N HIS 214.A O no hydrogen 3.324 N/A HIS 219.A NE2 TYR 202.A OH no hydrogen 2.837 N/A ASP 220.A N TRP 217.A O no hydrogen 3.419 N/A LEU 223.A N ILE 221.A O no hydrogen 3.051 N/A TRP 225.A N ASN 237.A O no hydrogen 2.961 N/A HIS 226.A ND1 ALA 227.A O no hydrogen 2.525 N/A HIS 235.A N ASP 230.A OD2 no hydrogen 3.137 N/A LYS 239.A NZ THR 88.A O no hydrogen 2.981 N/A LYS 239.A NZ HIS 235.A O no hydrogen 2.381 N/A LYS 239.A NZ TRP 236.A O no hydrogen 2.827 N/A GLU 240.A N GLU 240.A OE1 no hydrogen 2.931 N/A GLU 244.A N VAL 256.A O no hydrogen 2.605 N/A LYS 246.A N THR 254.A O no hydrogen 2.865 N/A LYS 246.A NZ ASP 247.A O no hydrogen 3.398 N/A ALA 248.A N ARG 252.A O no hydrogen 2.986 N/A THR 254.A N LYS 246.A O no hydrogen 2.714 N/A VAL 256.A N GLU 244.A O no hydrogen 2.957 N/A LEU 258.A N LEU 242.A O no hydrogen 2.618 N/A GLN 261.A N TYR 61.A O no hydrogen 2.709 N/A VAL 265.A N GLU 262.A O no hydrogen 3.343 N/A HIS 266.A N GLU 262.A O no hydrogen 3.182 N/A THR 267.A OG1 ALA 264.A O no hydrogen 3.416 N/A ALA 268.A N VAL 265.A O no hydrogen 2.965 N/A LEU 269.A N VAL 265.A O no hydrogen 2.808 N/A ALA 275.A N HIS 210.A O no hydrogen 2.897 N/A GLU 276.A N ARG 283.A O no hydrogen 3.209 N/A ASP 278.A N LYS 281.A O no hydrogen 3.231 N/A LYS 281.A NZ ASP 278.A OD1 no hydrogen 3.452 N/A LYS 281.A NZ ASP 278.A OD2 no hydrogen 3.470 N/A GLY 282.A N VAL 50.A O no hydrogen 2.691 N/A LEU 284.A N THR 48.A O no hydrogen 2.982 N/A SER 286.A OG SER 285.A O no hydrogen 2.739 N/A LEU 289.A N LEU 25.A O no hydrogen 2.872 N/A LYS 290.A NZ ASP 22.A OD1 no hydrogen 2.773 N/A LYS 290.A NZ ASP 22.A OD2 no hydrogen 2.827 N/A CYS 291.A N VAL 23.A O no hydrogen 2.695 N/A CYS 291.A SG ARG 292.A O no hydrogen 3.678 N/A LEU 293.A N VAL 21.A O no hydrogen 2.731 N/A LYS 294.A N GLY 187.A O no hydrogen 2.543 N/A MET 295.A N THR 19.A O no hydrogen 3.009 N/A ARG 299.A N PHE 183.A O no hydrogen 2.963 N/A CYS 308.A N LYS 340.A O no hydrogen 2.911 N/A THR 309.A N ASP 336.A OD2 no hydrogen 3.308 N/A THR 309.A OG1 TYR 332.A OH no hydrogen 3.371 N/A THR 309.A OG1 ASP 336.A OD2 no hydrogen 2.414 N/A THR 313.A OG1 PHE 312.A O no hydrogen 2.679 N/A ALA 319.A N THR 327.A O no hydrogen 3.463 N/A THR 321.A N THR 325.A O no hydrogen 2.746 N/A THR 321.A OG1 THR 325.A O no hydrogen 2.980 N/A THR 325.A OG1 THR 321.A OG1 no hydrogen 2.330 N/A THR 325.A OG1 GLU 377.A OE2 no hydrogen 2.876 N/A VAL 326.A N LEU 378.A O no hydrogen 3.043 N/A THR 327.A N ALA 319.A O no hydrogen 3.119 N/A VAL 330.A N MET 374.A O no hydrogen 2.550 N/A GLN 331.A N THR 313.A O no hydrogen 2.512 N/A TYR 332.A N SER 372.A O no hydrogen 3.190 N/A TYR 332.A OH THR 309.A OG1 no hydrogen 3.371 N/A ALA 333.A N ALA 311.A O no hydrogen 2.723 N/A GLY 334.A N GLU 370.A O no hydrogen 2.957 N/A CYS 339.A SG GLY 337.A O no hydrogen 3.301 N/A LYS 340.A N SER 306.A O no hydrogen 2.792 N/A VAL 341.A N PRO 363.A O no hydrogen 2.871 N/A GLN 344.A N VAL 388.A O no hydrogen 3.068 N/A ALA 346.A N TYR 386.A O no hydrogen 2.858 N/A THR 351.A OG1 ASP 348.A OD2 no hydrogen 2.877 N/A ILE 359.A N GLU 377.A O no hydrogen 3.043 N/A THR 360.A N GLU 377.A O no hydrogen 3.241 N/A THR 360.A OG1 THR 360.A O no hydrogen 2.453 N/A SER 372.A N TYR 332.A O no hydrogen 3.125 N/A SER 372.A OG GLU 367.A O no hydrogen 3.422 N/A MET 374.A N VAL 330.A O no hydrogen 2.767 N/A MET 375.A N GLN 147.A O no hydrogen 2.925 N/A LEU 376.A N VAL 328.A O no hydrogen 2.505 N/A LEU 378.A N VAL 326.A O no hydrogen 3.114 N/A ASP 379.A N ARG 357.A O no hydrogen 2.968 N/A SER 385.A N TRP 400.A O no hydrogen 2.807 N/A SER 385.A OG TRP 400.A O no hydrogen 3.426 N/A TYR 386.A N ALA 346.A O no hydrogen 2.690 N/A ILE 387.A N HIS 398.A O no hydrogen 2.986 N/A ILE 389.A N ILE 396.A O no hydrogen 2.803 N/A GLY 390.A N PRO 342.A O no hydrogen 3.348 N/A ILE 396.A N ILE 389.A O no hydrogen 2.671 N/A TRP 400.A N SER 385.A O no hydrogen 2.643 N/A HIS 401.A ND1 ASP 384.A OD1 no hydrogen 3.091 N/A ARG 402.A N GLY 383.A O no hydrogen 3.400 N/A ARG 402.A NH1 PRO 380.A O no hydrogen 2.411 N/A GLY 408.A N SER 405.A OG no hydrogen 3.034 N/A LYS 409.A N THR 406.A O no hydrogen 3.008 N/A ALA 410.A N THR 406.A O no hydrogen 2.791 N/A PHE 411.A N ILE 407.A O no hydrogen 3.074 N/A ALA 413.A N LYS 409.A O no hydrogen 2.987 N/A THR 414.A N ALA 410.A O no hydrogen 2.917 N/A THR 414.A OG1 ALA 410.A O no hydrogen 3.070 N/A VAL 415.A N PHE 411.A O no hydrogen 3.184 N/A ARG 416.A N GLU 412.A O no hydrogen 3.036 N/A ARG 416.A NH2 ARG 9.A O no hydrogen 2.506 N/A GLY 417.A N ALA 413.A O no hydrogen 2.719 N/A ALA 418.A N THR 414.A O no hydrogen 2.818 N/A LYS 419.A N VAL 415.A O no hydrogen 3.128 N/A ARG 420.A N ARG 416.A O no hydrogen 3.325 N/A ARG 420.A NH2 ASP 10.A OD1 no hydrogen 2.959 N/A MET 421.A N GLY 417.A O no hydrogen 3.196 N/A ALA 422.A N ALA 418.A O no hydrogen 2.812 N/A LEU 424.A N ARG 420.A O no hydrogen 3.028 N/A GLY 425.A N MET 421.A O no hydrogen 3.017 N/A TRP 429.A N ASP 426.A O no hydrogen 3.417 N/A ASP 430.A N THR 427.A O no hydrogen 2.878 N/A SER 433.A OG ASP 430.A OD1 no hydrogen 3.410 N/A GLY 442.A N LEU 438.A O no hydrogen 3.121 N/A LYS 443.A NZ ASP 430.A OD1 no hydrogen 3.516 N/A LYS 443.A NZ ASP 430.A OD2 no hydrogen 2.414 N/A ILE 445.A N LEU 441.A O no hydrogen 3.021 N/A HIS 446.A N GLY 442.A O no hydrogen 3.225 N/A HIS 446.A N LYS 443.A O no hydrogen 3.004 N/A GLN 447.A N LYS 443.A O no hydrogen 2.611 N/A PHE 449.A N ILE 445.A O no hydrogen 3.475 N/A GLY 450.A N HIS 446.A O no hydrogen 2.636 N/A ALA 451.A N GLN 447.A O no hydrogen 3.298 N/A ALA 451.A N ILE 448.A O no hydrogen 3.279 N/A ALA 452.A N ILE 448.A O no hydrogen 3.050 N/A LYS 454.A N GLY 450.A O no hydrogen 3.279 N/A SER 455.A OG ALA 451.A O no hydrogen 3.130 N/A PHE 457.A N PHE 453.A O no hydrogen 3.225 N/A SER 461.A N SER 464.A OG no hydrogen 2.504 N/A SER 461.A OG SER 464.A OG no hydrogen 3.012 N/A TRP 462.A NE1 LEU 498.A O no hydrogen 2.848 N/A SER 464.A OG SER 461.A OG no hydrogen 3.012 N/A GLN 465.A N SER 461.A O no hydrogen 3.103 N/A ILE 466.A N TRP 462.A O no hydrogen 3.526 N/A LEU 467.A N PHE 463.A O no hydrogen 2.911 N/A ILE 468.A N GLN 465.A O no hydrogen 3.199 N/A GLY 469.A N GLN 465.A O no hydrogen 2.585 N/A THR 470.A N ILE 466.A O no hydrogen 2.929 N/A THR 470.A OG1 ILE 466.A O no hydrogen 2.644 N/A LEU 472.A N ILE 468.A O no hydrogen 2.925 N/A MET 473.A N GLY 469.A O no hydrogen 2.851 N/A TRP 474.A N THR 470.A O no hydrogen 3.020 N/A LEU 475.A N LEU 471.A O no hydrogen 2.923 N/A GLY 476.A N MET 473.A O no hydrogen 2.955 N/A LEU 477.A N MET 473.A O no hydrogen 3.087 N/A GLY 482.A N ASN 481.A OD1 no hydrogen 2.759 N/A CYS 488.A N SER 485.A O no hydrogen 3.290 N/A CYS 488.A SG ILE 484.A O no hydrogen 3.647 N/A LEU 489.A N SER 485.A O no hydrogen 2.742 N/A GLY 493.A N LEU 489.A O no hydrogen 3.402 N/A VAL 494.A N LEU 491.A O no hydrogen 3.224 N/A LEU 495.A N LEU 491.A O no hydrogen 2.841 N/A LEU 498.A N LEU 495.A O no hydrogen 3.151 N/A SER 499.A N ILE 496.A O no hydrogen 2.509 N/A THR 500.A N ILE 496.A O no hydrogen 3.058 N/A THR 500.A OG1 THR 500.A O no hydrogen 2.065 N/A