Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6cqd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N GLN 55.A OE1 no hydrogen 3.145 N/A ASP 6.A N ASP 4.A OD2 no hydrogen 2.828 N/A ILE 7.A N ASP 4.A O no hydrogen 3.236 N/A PHE 8.A N SER 75.A O no hydrogen 2.781 N/A ARG 13.A N ASP 11.A OD1 no hydrogen 3.116 N/A ASP 14.A N ASP 11.A O no hydrogen 2.812 N/A HIS 15.A N PRO 12.A O no hydrogen 2.885 N/A TYR 16.A N PRO 12.A O no hydrogen 2.871 N/A ASP 17.A N ARG 34.A O no hydrogen 2.870 N/A LEU 19.A N LYS 32.A O no hydrogen 2.797 N/A GLN 20.A N LYS 32.A O no hydrogen 3.437 N/A LEU 22.A N VAL 30.A O no hydrogen 2.673 N/A VAL 30.A N GLY 23.A O no hydrogen 3.145 N/A PHE 31.A N LEU 44.A O no hydrogen 2.743 N/A LYS 32.A N GLN 20.A O no hydrogen 2.806 N/A ALA 33.A N VAL 42.A O no hydrogen 2.986 N/A ARG 34.A N ASP 17.A O no hydrogen 2.858 N/A ASP 35.A N ASP 40.A O no hydrogen 2.790 N/A LYS 36.A N HIS 15.A O no hydrogen 2.955 N/A LYS 36.A NZ ARG 13.A O no hydrogen 2.846 N/A VAL 37.A N ASP 35.A OD1 no hydrogen 2.965 N/A SER 38.A N ASP 35.A OD1 no hydrogen 3.083 N/A SER 38.A OG ASP 40.A OD2 no hydrogen 2.263 N/A GLY 39.A N ASP 35.A O no hydrogen 2.845 N/A VAL 42.A N ALA 33.A O no hydrogen 2.932 N/A ALA 43.A N MET 86.A O no hydrogen 2.821 N/A LEU 44.A N PHE 31.A O no hydrogen 2.863 N/A LYS 45.A N ILE 84.A O no hydrogen 2.753 N/A LYS 45.A NZ GLU 57.A OE2 no hydrogen 2.603 N/A LYS 45.A NZ ASP 150.A OD1 no hydrogen 3.290 N/A MET 46.A N GLU 29.A O no hydrogen 2.855 N/A VAL 47.A N LEU 82.A O no hydrogen 2.852 N/A SER 52.A OG ASP 1.A O no hydrogen 2.500 N/A THR 53.A N ASP 50.A O no hydrogen 3.044 N/A LEU 54.A N ASP 50.A O no hydrogen 2.685 N/A GLN 55.A N VAL 51.A O no hydrogen 3.115 N/A GLN 55.A NE2 VAL 2.A O no hydrogen 3.577 N/A GLU 57.A N LEU 54.A O no hydrogen 3.435 N/A LEU 59.A N GLN 55.A O no hydrogen 3.197 N/A ILE 60.A N LYS 56.A O no hydrogen 3.005 N/A LEU 61.A N GLU 57.A O no hydrogen 3.120 N/A LYS 62.A N ILE 58.A O no hydrogen 2.748 N/A LYS 62.A NZ ASP 4.A OD2 no hydrogen 3.029 N/A LYS 62.A NZ ASP 6.A OD2 no hydrogen 2.793 N/A THR 63.A N LEU 59.A O no hydrogen 2.983 N/A THR 63.A OG1 LEU 59.A O no hydrogen 2.745 N/A THR 63.A OG1 ILE 60.A O no hydrogen 2.982 N/A CYS 64.A N LEU 61.A O no hydrogen 3.213 N/A CYS 64.A SG ILE 60.A O no hydrogen 3.231 N/A ARG 65.A N TYR 122.A OH no hydrogen 3.197 N/A ASN 68.A N HIS 66.A ND1 no hydrogen 2.925 N/A ASN 68.A ND2 GLU 115.A OE1 no hydrogen 3.010 N/A ASN 68.A ND2 VAL 146.A O no hydrogen 2.981 N/A ILE 69.A N HIS 66.A O no hydrogen 3.020 N/A VAL 70.A N LEU 148.A O no hydrogen 2.873 N/A ALA 71.A N GLU 87.A OE1 no hydrogen 3.066 N/A TYR 72.A OH SER 75.A OG no hydrogen 2.565 N/A HIS 73.A N CYS 85.A O no hydrogen 2.673 N/A GLY 74.A N CYS 85.A O no hydrogen 2.971 N/A SER 75.A OG TYR 72.A OH no hydrogen 2.565 N/A TYR 76.A N TRP 83.A O no hydrogen 2.923 N/A LEU 77.A N PHE 8.A O no hydrogen 2.840 N/A TRP 78.A N LYS 81.A O no hydrogen 3.118 N/A LYS 81.A N TRP 78.A O no hydrogen 3.109 N/A TRP 83.A N TYR 76.A O no hydrogen 2.874 N/A ILE 84.A N LYS 45.A O no hydrogen 2.735 N/A CYS 85.A N GLY 74.A O no hydrogen 2.545 N/A CYS 85.A SG TYR 16.A OH no hydrogen 3.600 N/A MET 86.A N ALA 43.A O no hydrogen 2.871 N/A GLU 87.A N ALA 71.A O no hydrogen 2.792 N/A ALA 91.A N ILE 140.A O no hydrogen 3.097 N/A GLY 92.A N CYS 89.A O no hydrogen 2.970 N/A SER 93.A N ASP 96.A OD2 no hydrogen 3.117 N/A LEU 94.A N ILE 138.A O no hydrogen 2.903 N/A GLN 95.A NE2 GLN 99.A OE1 no hydrogen 3.118 N/A ASP 96.A N SER 93.A OG no hydrogen 3.122 N/A ILE 97.A N SER 93.A O no hydrogen 2.984 N/A TYR 98.A N LEU 94.A O no hydrogen 2.805 N/A TYR 98.A OH GLU 202.A OE2 no hydrogen 2.620 N/A GLN 99.A N GLN 95.A O no hydrogen 3.100 N/A VAL 100.A N ILE 97.A O no hydrogen 2.887 N/A THR 101.A N ILE 97.A O no hydrogen 2.959 N/A THR 101.A OG1 ILE 97.A O no hydrogen 3.434 N/A THR 101.A OG1 GLY 102.A O no hydrogen 3.127 N/A GLY 102.A N TYR 98.A O no hydrogen 2.803 N/A LEU 104.A N LEU 203.A O no hydrogen 3.157 N/A SER 105.A N GLN 108.A OE1 no hydrogen 2.969 N/A GLN 108.A N SER 105.A OG no hydrogen 3.143 N/A GLN 108.A NE2 LEU 278.A O no hydrogen 3.093 N/A ILE 109.A N SER 105.A O no hydrogen 2.908 N/A SER 110.A N GLU 106.A O no hydrogen 2.752 N/A SER 110.A OG GLU 106.A O no hydrogen 2.558 N/A TYR 111.A N LEU 107.A O no hydrogen 2.944 N/A VAL 112.A N GLN 108.A O no hydrogen 3.036 N/A CYS 113.A N ILE 109.A O no hydrogen 2.859 N/A CYS 113.A SG ILE 109.A O no hydrogen 3.419 N/A ARG 114.A N SER 110.A O no hydrogen 2.990 N/A ARG 114.A NE GLU 115.A OE2 no hydrogen 2.890 N/A ARG 114.A NH2 GLU 115.A OE2 no hydrogen 2.935 N/A GLU 115.A N TYR 111.A O no hydrogen 3.072 N/A VAL 116.A N VAL 112.A O no hydrogen 2.834 N/A LEU 117.A N CYS 113.A O no hydrogen 2.868 N/A GLN 118.A N ARG 114.A O no hydrogen 3.026 N/A GLY 119.A N GLU 115.A O no hydrogen 3.047 N/A LEU 120.A N VAL 116.A O no hydrogen 2.769 N/A ALA 121.A N LEU 117.A O no hydrogen 2.800 N/A TYR 122.A N GLN 118.A O no hydrogen 3.138 N/A LEU 123.A N GLY 119.A O no hydrogen 2.970 N/A HIS 124.A N LEU 120.A O no hydrogen 2.816 N/A HIS 124.A NE2 ASP 192.A OD2 no hydrogen 2.828 N/A SER 125.A N ALA 121.A O no hydrogen 3.063 N/A SER 125.A OG ALA 121.A O no hydrogen 3.549 N/A SER 125.A OG TYR 122.A O no hydrogen 2.626 N/A GLN 126.A N LEU 123.A O no hydrogen 3.016 N/A LYS 127.A N HIS 124.A O no hydrogen 2.924 N/A LYS 128.A N LEU 123.A O no hydrogen 2.937 N/A LYS 128.A NZ ILE 60.A O no hydrogen 3.415 N/A LYS 128.A NZ THR 63.A OG1 no hydrogen 2.724 N/A LYS 128.A NZ GLN 126.A OE1 no hydrogen 2.974 N/A HIS 130.A N ASP 192.A OD2 no hydrogen 2.943 N/A HIS 130.A NE2 ALA 149.A O no hydrogen 2.890 N/A ARG 131.A N ASP 192.A OD1 no hydrogen 2.755 N/A ARG 131.A NE ARG 131.A O no hydrogen 2.719 N/A ARG 131.A NH2 TYR 187.A OH no hydrogen 2.941 N/A ASP 132.A N HIS 130.A ND1 no hydrogen 3.019 N/A GLY 135.A N GLU 202.A OE1 no hydrogen 2.964 N/A ASN 137.A N LYS 134.A O no hydrogen 2.849 N/A ASN 137.A ND2 ASP 132.A O no hydrogen 2.722 N/A ILE 138.A N GLY 135.A O no hydrogen 3.128 N/A LEU 139.A N ARG 147.A O no hydrogen 2.771 N/A ILE 140.A N GLY 92.A O no hydrogen 2.861 N/A ASN 141.A N GLU 145.A O no hydrogen 3.297 N/A ASN 141.A ND2 GLU 87.A OE2 no hydrogen 2.987 N/A ASN 141.A ND2 GLU 145.A OE1 no hydrogen 2.649 N/A ALA 143.A N ASN 141.A OD1 no hydrogen 3.087 N/A GLY 144.A N ASN 141.A O no hydrogen 2.942 N/A GLU 145.A N ASN 141.A OD1 no hydrogen 2.886 N/A ARG 147.A N LEU 139.A O no hydrogen 2.859 N/A ARG 147.A NH1 GLU 145.A OE1 no hydrogen 2.993 N/A ARG 147.A NH2 ILE 69.A O no hydrogen 3.385 N/A LEU 148.A N ASN 68.A O no hydrogen 2.751 N/A ALA 149.A N ASN 137.A O no hydrogen 2.945 N/A SER 154.A OG ILE 129.A O no hydrogen 2.676 N/A ALA 155.A N PHE 151.A O no hydrogen 2.883 N/A ALA 155.A N GLY 152.A O no hydrogen 3.209 N/A GLN 156.A N ILE 153.A O no hydrogen 2.924 N/A ILE 157.A N ILE 153.A O no hydrogen 3.367 N/A GLY 158.A N SER 154.A O no hydrogen 2.992 N/A ALA 159.A N ALA 155.A O no hydrogen 3.098 N/A GLU 160.A N ILE 157.A O no hydrogen 3.034 N/A LEU 161.A N ILE 157.A O no hydrogen 3.232 N/A LEU 161.A N GLY 158.A O no hydrogen 3.236 N/A ALA 162.A N GLY 158.A O no hydrogen 3.309 N/A MET 174.A N PRO 171.A O no hydrogen 2.911 N/A ALA 179.A N ALA 175.A O no hydrogen 2.804 N/A ALA 180.A N PRO 176.A O no hydrogen 2.979 N/A VAL 181.A N GLU 177.A O no hydrogen 3.364 N/A ALA 182.A N VAL 178.A O no hydrogen 2.955 N/A LEU 183.A N ALA 179.A O no hydrogen 2.923 N/A LEU 183.A N ALA 180.A O no hydrogen 3.171 N/A LYS 184.A N ALA 180.A O no hydrogen 2.743 N/A GLY 185.A N VAL 181.A O no hydrogen 2.882 N/A GLU 189.A N GLU 189.A OE1 no hydrogen 2.591 N/A LEU 190.A N ASN 188.A OD1 no hydrogen 3.066 N/A CYS 191.A N ASN 188.A O no hydrogen 3.088 N/A CYS 191.A SG ASN 188.A O no hydrogen 3.241 N/A ASP 192.A N GLU 189.A O no hydrogen 2.874 N/A ILE 193.A N LEU 190.A O no hydrogen 3.110 N/A TRP 194.A N LEU 190.A O no hydrogen 3.373 N/A SER 195.A N CYS 191.A O no hydrogen 3.141 N/A SER 195.A OG CYS 191.A O no hydrogen 3.142 N/A LEU 196.A N ASP 192.A O no hydrogen 3.000 N/A GLY 197.A N ILE 193.A O no hydrogen 3.217 N/A ILE 198.A N TRP 194.A O no hydrogen 3.086 N/A THR 199.A N SER 195.A O no hydrogen 2.834 N/A THR 199.A OG1 SER 195.A O no hydrogen 2.871 N/A ALA 200.A N LEU 196.A O no hydrogen 2.844 N/A ILE 201.A N GLY 197.A O no hydrogen 3.278 N/A GLU 202.A N ILE 198.A O no hydrogen 2.840 N/A LEU 203.A N THR 199.A O no hydrogen 2.774 N/A ALA 204.A N ALA 200.A O no hydrogen 3.063 N/A ALA 204.A N ILE 201.A O no hydrogen 3.039 N/A GLU 205.A N ILE 201.A O no hydrogen 2.825 N/A LEU 206.A N GLU 202.A O no hydrogen 2.714 N/A VAL 213.A N LEU 210.A O no hydrogen 3.154 N/A VAL 218.A N HIS 214.A O no hydrogen 2.984 N/A LEU 219.A N PRO 215.A O no hydrogen 2.871 N/A PHE 220.A N LEU 216.A O no hydrogen 2.899 N/A LEU 221.A N ARG 217.A O no hydrogen 2.843 N/A MET 222.A N VAL 218.A O no hydrogen 2.920 N/A THR 223.A N PHE 220.A O no hydrogen 3.256 N/A THR 223.A OG1 LEU 219.A O no hydrogen 3.061 N/A THR 223.A OG1 PHE 220.A O no hydrogen 2.661 N/A LYS 224.A N LEU 221.A O no hydrogen 3.069 N/A GLN 228.A NE2 GLY 226.A O no hydrogen 3.076 N/A ARG 231.A NH2 PRO 230.A O no hydrogen 2.874 N/A LYS 233.A N GLU 205.A OE2 no hydrogen 2.658 N/A SER 239.A N GLU 106.A OE1 no hydrogen 2.919 N/A SER 239.A OG GLU 106.A OE2 no hydrogen 2.542 N/A PHE 242.A N SER 239.A O no hydrogen 3.074 N/A PHE 242.A N SER 239.A OG no hydrogen 3.290 N/A HIS 243.A N SER 239.A O no hydrogen 3.161 N/A HIS 243.A NE2 LYS 235.A O no hydrogen 2.941 N/A ASN 244.A N ALA 240.A O no hydrogen 2.921 N/A PHE 245.A N ALA 241.A O no hydrogen 2.884 N/A ILE 246.A N PHE 242.A O no hydrogen 2.984 N/A LYS 247.A N HIS 243.A O no hydrogen 2.988 N/A VAL 248.A N ASN 244.A O no hydrogen 3.018 N/A THR 249.A N PHE 245.A O no hydrogen 3.055 N/A THR 249.A OG1 PHE 245.A O no hydrogen 2.934 N/A THR 249.A OG1 ILE 246.A O no hydrogen 3.118 N/A LEU 250.A N ILE 246.A O no hydrogen 2.926 N/A THR 251.A N VAL 248.A O no hydrogen 3.215 N/A THR 251.A OG1 VAL 248.A O no hydrogen 2.635 N/A LYS 255.A N SER 253.A OG no hydrogen 3.264 N/A LYS 256.A N SER 253.A O no hydrogen 2.945 N/A ARG 257.A NE THR 251.A O no hydrogen 2.740 N/A ARG 257.A NH1 LEU 190.A O no hydrogen 2.968 N/A ARG 257.A NH2 THR 251.A O no hydrogen 2.957 N/A ARG 257.A NH2 LYS 252.A O no hydrogen 3.048 N/A LYS 262.A N SER 259.A OG no hydrogen 3.098 N/A MET 263.A N SER 259.A O no hydrogen 2.879 N/A LEU 264.A N ALA 260.A O no hydrogen 2.962 N/A LEU 264.A N THR 261.A O no hydrogen 3.226 N/A SER 265.A N LYS 262.A O no hydrogen 2.976 N/A HIS 266.A N MET 263.A O no hydrogen 3.005 N/A HIS 266.A NE2 ASN 244.A OD1 no hydrogen 2.677 N/A GLN 267.A N GLN 267.A OE1 no hydrogen 2.692 N/A LEU 268.A N HIS 266.A ND1 no hydrogen 3.101 N/A VAL 269.A N HIS 266.A O no hydrogen 3.253 N/A SER 270.A N GLN 267.A O no hydrogen 3.407 N/A SER 270.A OG HIS 266.A O no hydrogen 3.102 N/A GLN 271.A NE2 LEU 268.A O no hydrogen 2.830 N/A LEU 274.A N GLN 271.A O no hydrogen 3.376 N/A ASN 275.A ND2 GLY 273.A O no hydrogen 3.408 N/A ARG 276.A NE ALA 143.A O no hydrogen 3.429 N/A ARG 276.A NH1 ALA 143.A O no hydrogen 3.094 N/A GLY 277.A N ASN 275.A OD1 no hydrogen 2.687 N/A LEU 278.A N ASN 275.A O no hydrogen 2.964 N/A ILE 279.A N ARG 276.A O no hydrogen 2.864 N/A LEU 280.A N ARG 276.A O no hydrogen 2.948 N/A ASP 281.A N GLY 277.A O no hydrogen 2.860 N/A LEU 282.A N LEU 278.A O no hydrogen 3.280 N/A LEU 283.A N ILE 279.A O no hydrogen 2.936 N/A ASP 284.A N LEU 280.A O no hydrogen 2.944 N/A LYS 285.A N ASP 281.A O no hydrogen 2.956 N/A LYS 285.A NZ THR 101.A O no hydrogen 2.988 N/A LEU 286.A N LEU 282.A O no hydrogen 2.828 N/A LYS 287.A N LEU 283.A O no hydrogen 2.900 N/A ASN 288.A N ASP 284.A O no hydrogen 3.038 N/A