Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6cqe_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N ASP 2.A OD2 no hydrogen 3.100 N/A PHE 6.A N SER 73.A O no hydrogen 2.625 N/A ARG 11.A N ASP 9.A OD1 no hydrogen 3.075 N/A ARG 11.A NH1 ASP 9.A OD2 no hydrogen 3.096 N/A ASP 12.A N ASP 9.A O no hydrogen 2.854 N/A HIS 13.A N PRO 10.A O no hydrogen 2.827 N/A TYR 14.A N PRO 10.A O no hydrogen 3.050 N/A ASP 15.A N ARG 28.A O no hydrogen 2.892 N/A LEU 17.A N LYS 26.A O no hydrogen 2.842 N/A GLN 18.A N LYS 26.A O no hydrogen 3.421 N/A LEU 20.A N VAL 24.A O no hydrogen 2.773 N/A GLU 23.A N MET 40.A O no hydrogen 2.951 N/A PHE 25.A N LEU 38.A O no hydrogen 2.806 N/A LYS 26.A N GLN 18.A O no hydrogen 2.872 N/A ALA 27.A N VAL 36.A O no hydrogen 2.825 N/A ARG 28.A N ASP 15.A O no hydrogen 2.852 N/A ASP 29.A N ASP 34.A O no hydrogen 2.808 N/A LYS 30.A N HIS 13.A O no hydrogen 2.790 N/A LYS 30.A NZ ARG 11.A O no hydrogen 2.902 N/A LYS 30.A NZ TYR 14.A O no hydrogen 3.090 N/A LYS 30.A NZ ASP 15.A OD1 no hydrogen 3.258 N/A VAL 31.A N ASP 29.A OD2 no hydrogen 2.693 N/A SER 32.A N ASP 29.A OD2 no hydrogen 3.292 N/A GLY 33.A N ASP 29.A O no hydrogen 3.025 N/A ASP 34.A N SER 32.A OG no hydrogen 3.122 N/A VAL 36.A N ALA 27.A O no hydrogen 2.712 N/A ALA 37.A N MET 84.A O no hydrogen 2.862 N/A LEU 38.A N PHE 25.A O no hydrogen 2.843 N/A LYS 39.A N ILE 82.A O no hydrogen 2.884 N/A MET 40.A N GLU 23.A O no hydrogen 2.664 N/A VAL 41.A N LEU 80.A O no hydrogen 2.882 N/A MET 43.A N GLN 78.A O no hydrogen 2.811 N/A GLU 44.A N ASP 47.A OD2 no hydrogen 2.677 N/A ASP 47.A N GLU 44.A O no hydrogen 2.768 N/A SER 50.A N ASP 48.A OD2 no hydrogen 2.959 N/A SER 50.A OG ASP 48.A OD1 no hydrogen 2.900 N/A SER 50.A OG ASP 48.A OD2 no hydrogen 2.635 N/A THR 51.A N ASP 48.A O no hydrogen 3.137 N/A THR 51.A OG1 ASP 48.A O no hydrogen 2.759 N/A LEU 52.A N VAL 49.A O no hydrogen 2.935 N/A GLN 53.A N SER 50.A O no hydrogen 3.327 N/A ILE 56.A N LEU 52.A O no hydrogen 3.000 N/A LEU 57.A N GLN 53.A O no hydrogen 2.861 N/A ILE 58.A N LYS 54.A O no hydrogen 3.043 N/A LEU 59.A N GLU 55.A O no hydrogen 3.192 N/A LYS 60.A N ILE 56.A O no hydrogen 2.810 N/A LYS 60.A NZ ASP 2.A O no hydrogen 2.247 N/A LYS 60.A NZ ASP 4.A OD2 no hydrogen 2.435 N/A THR 61.A N LEU 57.A O no hydrogen 3.055 N/A THR 61.A OG1 LEU 57.A O no hydrogen 3.017 N/A THR 61.A OG1 ILE 58.A O no hydrogen 3.449 N/A CYS 62.A N LEU 59.A O no hydrogen 3.080 N/A CYS 62.A SG ILE 58.A O no hydrogen 3.398 N/A ARG 63.A N TYR 120.A OH no hydrogen 2.629 N/A ASN 66.A N HIS 64.A ND1 no hydrogen 2.833 N/A ASN 66.A ND2 GLU 113.A OE2 no hydrogen 2.957 N/A ASN 66.A ND2 VAL 144.A O no hydrogen 2.962 N/A ILE 67.A N HIS 64.A O no hydrogen 3.143 N/A VAL 68.A N LEU 146.A O no hydrogen 3.015 N/A ALA 69.A N GLU 85.A OE1 no hydrogen 3.015 N/A TYR 70.A OH PRO 3.A O no hydrogen 2.762 N/A TYR 70.A OH SER 73.A OG no hydrogen 2.810 N/A HIS 71.A N CYS 83.A O no hydrogen 2.850 N/A SER 73.A N ASP 4.A O no hydrogen 3.010 N/A SER 73.A OG TYR 70.A OH no hydrogen 2.810 N/A TYR 74.A N TRP 81.A O no hydrogen 2.756 N/A LEU 75.A N PHE 6.A O no hydrogen 2.819 N/A TRP 76.A N LYS 79.A O no hydrogen 2.825 N/A LYS 79.A N TRP 76.A O no hydrogen 2.918 N/A LEU 80.A N VAL 41.A O no hydrogen 2.934 N/A TRP 81.A N TYR 74.A O no hydrogen 2.734 N/A ILE 82.A N LYS 39.A O no hydrogen 2.804 N/A CYS 83.A N GLY 72.A O no hydrogen 2.726 N/A CYS 83.A SG TYR 14.A OH no hydrogen 3.438 N/A MET 84.A N ALA 37.A O no hydrogen 2.856 N/A GLU 85.A N ALA 69.A O no hydrogen 2.893 N/A ALA 89.A N ILE 138.A O no hydrogen 3.038 N/A GLY 90.A N CYS 87.A O no hydrogen 3.165 N/A SER 91.A N ASP 94.A OD2 no hydrogen 2.973 N/A LEU 92.A N ILE 136.A O no hydrogen 2.914 N/A ASP 94.A N SER 91.A OG no hydrogen 3.072 N/A ILE 95.A N SER 91.A O no hydrogen 2.994 N/A TYR 96.A N LEU 92.A O no hydrogen 2.766 N/A TYR 96.A OH GLU 200.A OE2 no hydrogen 2.507 N/A GLN 97.A N GLN 93.A O no hydrogen 3.121 N/A VAL 98.A N ILE 95.A O no hydrogen 3.013 N/A THR 99.A N ILE 95.A O no hydrogen 2.985 N/A THR 99.A OG1 ILE 95.A O no hydrogen 3.254 N/A THR 99.A OG1 GLY 100.A O no hydrogen 2.986 N/A GLY 100.A N TYR 96.A O no hydrogen 2.880 N/A LEU 102.A N LEU 201.A O no hydrogen 3.098 N/A SER 103.A N GLN 106.A OE1 no hydrogen 2.898 N/A GLN 106.A N SER 103.A OG no hydrogen 3.014 N/A GLN 106.A NE2 LEU 276.A O no hydrogen 3.022 N/A ILE 107.A N SER 103.A O no hydrogen 2.958 N/A SER 108.A N GLU 104.A O no hydrogen 2.814 N/A SER 108.A OG GLU 104.A O no hydrogen 2.782 N/A TYR 109.A N LEU 105.A O no hydrogen 2.953 N/A TYR 109.A OH GLY 142.A O no hydrogen 3.043 N/A VAL 110.A N GLN 106.A O no hydrogen 3.029 N/A CYS 111.A N ILE 107.A O no hydrogen 2.856 N/A CYS 111.A SG ILE 107.A O no hydrogen 3.355 N/A ARG 112.A N SER 108.A O no hydrogen 3.032 N/A ARG 112.A NE GLU 113.A OE1 no hydrogen 3.021 N/A ARG 112.A NH1 LEU 272.A O no hydrogen 3.075 N/A ARG 112.A NH2 GLU 113.A OE1 no hydrogen 2.991 N/A ARG 112.A NH2 LEU 272.A O no hydrogen 3.481 N/A GLU 113.A N TYR 109.A O no hydrogen 2.992 N/A VAL 114.A N VAL 110.A O no hydrogen 2.846 N/A LEU 115.A N CYS 111.A O no hydrogen 2.853 N/A GLN 116.A N ARG 112.A O no hydrogen 2.977 N/A GLY 117.A N GLU 113.A O no hydrogen 3.080 N/A LEU 118.A N VAL 114.A O no hydrogen 2.760 N/A ALA 119.A N LEU 115.A O no hydrogen 2.808 N/A TYR 120.A N GLN 116.A O no hydrogen 3.122 N/A LEU 121.A N GLY 117.A O no hydrogen 2.975 N/A HIS 122.A N LEU 118.A O no hydrogen 2.826 N/A HIS 122.A NE2 ASP 190.A OD2 no hydrogen 2.831 N/A SER 123.A N ALA 119.A O no hydrogen 2.989 N/A SER 123.A OG TYR 120.A O no hydrogen 2.617 N/A SER 123.A OG GLN 124.A OE1 no hydrogen 3.125 N/A GLN 124.A N TYR 120.A O no hydrogen 3.168 N/A GLN 124.A N LEU 121.A O no hydrogen 2.854 N/A LYS 125.A N HIS 122.A O no hydrogen 2.939 N/A LYS 126.A N LEU 121.A O no hydrogen 2.947 N/A LYS 126.A NZ ILE 58.A O no hydrogen 2.807 N/A LYS 126.A NZ THR 61.A OG1 no hydrogen 2.678 N/A HIS 128.A N ASP 190.A OD2 no hydrogen 2.842 N/A HIS 128.A NE2 ALA 147.A O no hydrogen 2.685 N/A ARG 129.A N ASP 190.A OD1 no hydrogen 2.825 N/A ASP 130.A N HIS 128.A ND1 no hydrogen 3.009 N/A GLY 133.A N GLU 200.A OE1 no hydrogen 2.892 N/A ASN 135.A N LYS 132.A O no hydrogen 2.965 N/A ASN 135.A ND2 ASP 130.A O no hydrogen 2.841 N/A ASN 135.A ND2 ASP 130.A OD2 no hydrogen 3.155 N/A ILE 136.A N GLY 133.A O no hydrogen 3.194 N/A LEU 137.A N ARG 145.A O no hydrogen 2.720 N/A ILE 138.A N GLY 90.A O no hydrogen 2.930 N/A ASN 139.A N GLU 143.A O no hydrogen 3.083 N/A ASN 139.A ND2 GLU 143.A OE1 no hydrogen 2.926 N/A ALA 141.A N ASN 139.A OD1 no hydrogen 3.020 N/A GLY 142.A N ASN 139.A O no hydrogen 2.839 N/A GLU 143.A N ASN 139.A OD1 no hydrogen 2.911 N/A ARG 145.A N LEU 137.A O no hydrogen 2.815 N/A ARG 145.A NE GLU 85.A OE1 no hydrogen 3.471 N/A ARG 145.A NE GLU 85.A OE2 no hydrogen 2.775 N/A ARG 145.A NH2 VAL 144.A O no hydrogen 3.171 N/A LEU 146.A N ASN 66.A O no hydrogen 2.820 N/A ALA 147.A N ASN 135.A O no hydrogen 2.877 N/A ILE 151.A N ASP 148.A OD2 no hydrogen 2.952 N/A ALA 153.A N PHE 149.A O no hydrogen 2.866 N/A GLN 154.A N GLY 150.A O no hydrogen 3.297 N/A ILE 155.A N ILE 151.A O no hydrogen 3.078 N/A GLY 156.A N SER 152.A O no hydrogen 2.857 N/A ALA 157.A N ALA 153.A O no hydrogen 2.935 N/A THR 158.A N GLN 154.A O no hydrogen 3.032 N/A THR 158.A OG1 GLN 154.A O no hydrogen 3.295 N/A LEU 159.A N ILE 155.A O no hydrogen 3.107 N/A ALA 160.A N GLY 156.A O no hydrogen 2.960 N/A ARG 161.A N ALA 157.A O no hydrogen 2.795 N/A ARG 162.A N THR 158.A O no hydrogen 2.956 N/A ARG 162.A NH1 ASP 47.A OD1 no hydrogen 3.543 N/A ARG 162.A NH1 ASP 47.A OD2 no hydrogen 3.361 N/A LEU 163.A N LEU 159.A O no hydrogen 3.101 N/A ALA 164.A N ARG 161.A O no hydrogen 2.968 N/A PHE 165.A N ALA 160.A O no hydrogen 2.912 N/A ILE 166.A N ALA 160.A O no hydrogen 3.403 N/A MET 172.A N PRO 169.A O no hydrogen 2.929 N/A GLU 175.A N GLU 175.A OE2 no hydrogen 2.794 N/A ALA 177.A N ALA 173.A O no hydrogen 2.923 N/A ALA 178.A N PRO 174.A O no hydrogen 2.870 N/A VAL 179.A N GLU 175.A O no hydrogen 3.154 N/A ALA 180.A N VAL 176.A O no hydrogen 3.018 N/A LEU 181.A N ALA 177.A O no hydrogen 3.108 N/A LEU 181.A N ALA 178.A O no hydrogen 3.145 N/A LYS 182.A N ALA 178.A O no hydrogen 2.862 N/A GLY 183.A N VAL 179.A O no hydrogen 2.543 N/A TYR 185.A N LYS 182.A O no hydrogen 3.257 N/A LEU 188.A N ASN 186.A OD1 no hydrogen 2.991 N/A CYS 189.A N ASN 186.A O no hydrogen 2.882 N/A CYS 189.A SG ASN 186.A O no hydrogen 2.976 N/A ASP 190.A N GLU 187.A O no hydrogen 3.193 N/A ILE 191.A N LEU 188.A O no hydrogen 3.058 N/A TRP 192.A N LEU 188.A O no hydrogen 3.415 N/A SER 193.A N CYS 189.A O no hydrogen 3.060 N/A SER 193.A OG CYS 189.A O no hydrogen 3.234 N/A LEU 194.A N ASP 190.A O no hydrogen 2.977 N/A GLY 195.A N ILE 191.A O no hydrogen 3.108 N/A ILE 196.A N TRP 192.A O no hydrogen 3.091 N/A THR 197.A N SER 193.A O no hydrogen 2.881 N/A THR 197.A OG1 SER 193.A O no hydrogen 2.874 N/A ALA 198.A N LEU 194.A O no hydrogen 2.873 N/A ILE 199.A N GLY 195.A O no hydrogen 3.320 N/A GLU 200.A N ILE 196.A O no hydrogen 2.902 N/A LEU 201.A N THR 197.A O no hydrogen 2.857 N/A ALA 202.A N ALA 198.A O no hydrogen 3.059 N/A GLU 203.A N ILE 199.A O no hydrogen 2.801 N/A LEU 204.A N GLU 200.A O no hydrogen 2.701 N/A PHE 209.A N PRO 206.A O no hydrogen 3.315 N/A VAL 211.A N LEU 208.A O no hydrogen 2.885 N/A LEU 214.A N HIS 212.A ND1 no hydrogen 2.971 N/A VAL 216.A N HIS 212.A O no hydrogen 2.900 N/A LEU 217.A N PRO 213.A O no hydrogen 2.889 N/A PHE 218.A N LEU 214.A O no hydrogen 2.994 N/A LEU 219.A N ARG 215.A O no hydrogen 2.897 N/A MET 220.A N VAL 216.A O no hydrogen 2.769 N/A THR 221.A OG1 LEU 217.A O no hydrogen 2.901 N/A THR 221.A OG1 PHE 218.A O no hydrogen 3.329 N/A LYS 222.A N LEU 219.A O no hydrogen 3.460 N/A TYR 225.A N LYS 222.A O no hydrogen 3.285 N/A GLN 226.A NE2 GLY 224.A O no hydrogen 3.411 N/A ARG 229.A NH2 PRO 228.A O no hydrogen 2.605 N/A LYS 231.A N GLU 203.A OE2 no hydrogen 2.663 N/A LYS 231.A NZ GLU 203.A OE1 no hydrogen 3.059 N/A LYS 233.A NZ LEU 230.A O no hydrogen 2.711 N/A LYS 235.A N GLU 232.A O no hydrogen 3.311 N/A TRP 236.A N LYS 233.A O no hydrogen 3.281 N/A SER 237.A N GLU 104.A OE2 no hydrogen 2.970 N/A SER 237.A OG GLU 104.A OE1 no hydrogen 2.429 N/A SER 237.A OG GLU 104.A OE2 no hydrogen 3.373 N/A PHE 240.A N SER 237.A OG no hydrogen 3.042 N/A HIS 241.A N SER 237.A O no hydrogen 3.054 N/A HIS 241.A NE2 LYS 233.A O no hydrogen 2.900 N/A ASN 242.A N ALA 238.A O no hydrogen 2.850 N/A PHE 243.A N ALA 239.A O no hydrogen 2.844 N/A ILE 244.A N PHE 240.A O no hydrogen 3.005 N/A LYS 245.A N HIS 241.A O no hydrogen 2.950 N/A VAL 246.A N ASN 242.A O no hydrogen 2.981 N/A THR 247.A N PHE 243.A O no hydrogen 3.033 N/A THR 247.A OG1 PHE 243.A O no hydrogen 2.955 N/A THR 247.A OG1 ILE 244.A O no hydrogen 3.349 N/A LEU 248.A N ILE 244.A O no hydrogen 3.044 N/A THR 249.A OG1 VAL 246.A O no hydrogen 2.709 N/A LYS 250.A NZ SER 223.A O no hydrogen 2.397 N/A LYS 250.A NZ TYR 225.A O no hydrogen 2.834 N/A LYS 253.A N SER 251.A OG no hydrogen 3.255 N/A LYS 254.A N SER 251.A O no hydrogen 2.881 N/A ARG 255.A NE THR 249.A O no hydrogen 2.733 N/A ARG 255.A NH1 LEU 188.A O no hydrogen 2.946 N/A ARG 255.A NH2 THR 249.A O no hydrogen 3.046 N/A ARG 255.A NH2 LYS 250.A O no hydrogen 3.030 N/A LYS 260.A N SER 257.A OG no hydrogen 3.046 N/A MET 261.A N SER 257.A O no hydrogen 2.871 N/A LEU 262.A N ALA 258.A O no hydrogen 2.938 N/A LEU 262.A N THR 259.A O no hydrogen 3.179 N/A SER 263.A N LYS 260.A O no hydrogen 3.051 N/A HIS 264.A N MET 261.A O no hydrogen 2.880 N/A HIS 264.A NE2 ASN 242.A OD1 no hydrogen 2.707 N/A LEU 266.A N HIS 264.A ND1 no hydrogen 3.089 N/A VAL 267.A N HIS 264.A O no hydrogen 3.173 N/A SER 268.A N HIS 264.A O no hydrogen 2.900 N/A SER 268.A OG HIS 264.A O no hydrogen 2.916 N/A GLN 269.A NE2 LEU 266.A O no hydrogen 2.764 N/A ARG 274.A NH1 ALA 141.A O no hydrogen 2.881 N/A GLY 275.A N ASN 273.A OD1 no hydrogen 2.899 N/A LEU 276.A N ASN 273.A O no hydrogen 3.037 N/A ILE 277.A N ARG 274.A O no hydrogen 2.871 N/A LEU 278.A N ARG 274.A O no hydrogen 2.896 N/A ASP 279.A N GLY 275.A O no hydrogen 2.993 N/A LEU 281.A N ILE 277.A O no hydrogen 2.830 N/A ASP 282.A N LEU 278.A O no hydrogen 2.992 N/A LYS 283.A N ASP 279.A O no hydrogen 2.992 N/A LYS 283.A NZ THR 99.A O no hydrogen 2.938 N/A LEU 284.A N LEU 280.A O no hydrogen 2.823 N/A LYS 285.A N LEU 281.A O no hydrogen 3.094 N/A LYS 285.A NZ LEU 281.A O no hydrogen 3.132 N/A ASN 286.A N ASP 282.A O no hydrogen 2.849 N/A ASN 286.A ND2 ASP 282.A OD1 no hydrogen 3.140 N/A ASN 287.A N LYS 283.A O no hydrogen 2.908 N/A