Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6cvz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A N GLU 337.A O no hydrogen 3.045 N/A TYR 4.A N GLN 301.A OE1 no hydrogen 2.819 N/A HIS 5.A N LYS 335.A O no hydrogen 2.793 N/A GLN 7.A N ILE 333.A O no hydrogen 2.740 N/A LYS 8.A N ILE 333.A O no hydrogen 3.304 N/A THR 9.A OG1 HIS 332.A ND1 no hydrogen 2.775 N/A PHE 10.A N VAL 331.A O no hydrogen 2.935 N/A VAL 12.A N LYS 329.A O no hydrogen 2.859 N/A SER 13.A N LYS 329.A O no hydrogen 3.096 N/A SER 13.A OG GLY 16.A O no hydrogen 2.675 N/A GLY 16.A N SER 13.A O no hydrogen 2.832 N/A ASN 17.A N GLU 328.A OE1 no hydrogen 2.891 N/A ASN 17.A ND2 ALA 15.A O no hydrogen 2.786 N/A CYS 18.A N GLU 328.A O no hydrogen 3.158 N/A CYS 18.A SG GLU 328.A O no hydrogen 3.430 N/A ARG 19.A N SER 33.A OG no hydrogen 3.160 N/A ARG 19.A NH1 CYS 18.A O no hydrogen 2.654 N/A ILE 20.A N SER 33.A OG no hydrogen 3.027 N/A MET 21.A N ASP 311.A OD2 no hydrogen 2.798 N/A ALA 22.A N VAL 31.A O no hydrogen 3.003 N/A TYR 23.A OH THR 52.A OG1 no hydrogen 2.842 N/A TYR 23.A OH GLU 316.A O no hydrogen 3.066 N/A CYS 24.A N CYS 29.A O no hydrogen 2.866 N/A SER 28.A N ASP 25.A O no hydrogen 3.307 N/A CYS 29.A N CYS 24.A O no hydrogen 3.159 N/A CYS 29.A SG LEU 30.A O no hydrogen 4.021 N/A CYS 29.A SG LEU 50.A O no hydrogen 3.925 N/A LEU 30.A N LEU 50.A O no hydrogen 2.913 N/A VAL 31.A N ALA 22.A O no hydrogen 2.903 N/A ILE 32.A N.A LYS 48.A O no hydrogen 2.932 N/A ILE 32.A N.B LYS 48.A O no hydrogen 2.942 N/A SER 33.A N ILE 20.A O no hydrogen 2.842 N/A SER 33.A OG ILE 20.A O no hydrogen 3.535 N/A GLN 34.A N GLY 46.A O no hydrogen 2.960 N/A GLN 34.A NE2 PRO 35.A O no hydrogen 2.813 N/A SER 36.A N GLY 44.A O no hydrogen 2.835 N/A SER 36.A OG LEU 42.A O no hydrogen 2.997 N/A SER 36.A OG GLY 44.A O no hydrogen 3.447 N/A GLN 38.A NE2 SER 36.A O no hydrogen 2.871 N/A SER 40.A N PRO 37.A O no hydrogen 3.402 N/A PHE 41.A N PRO 37.A O no hydrogen 3.166 N/A PHE 45.A N HIS 63.A O no hydrogen 2.859 N/A GLY 46.A N GLN 34.A O no hydrogen 2.962 N/A VAL 47.A N ILE 60.A O no hydrogen 3.187 N/A LYS 48.A N ILE 32.A O.A no hydrogen 2.933 N/A LYS 48.A N ILE 32.A O.B no hydrogen 2.946 N/A MET 49.A N GLN 58.A O no hydrogen 2.882 N/A LEU 50.A N LEU 30.A O no hydrogen 2.665 N/A THR 52.A N SER 28.A O no hydrogen 2.936 N/A THR 52.A OG1 TYR 23.A OH no hydrogen 2.842 N/A ASN 54.A N SER 51.A OG no hydrogen 3.303 N/A ASN 54.A ND2 SER 51.A OG no hydrogen 3.422 N/A LYS 56.A N SER 51.A O no hydrogen 3.340 N/A ILE 60.A N VAL 47.A O no hydrogen 2.923 N/A MET 62.A N PHE 45.A O no hydrogen 2.992 N/A HIS 63.A N PHE 45.A O no hydrogen 2.902 N/A HIS 63.A ND1 ASP 86.A OD2 no hydrogen 2.892 N/A HIS 63.A NE2 SER 82.A OG no hydrogen 2.728 N/A GLY 64.A N ASP 86.A OD2 no hydrogen 3.083 N/A GLN 66.A NE2 ASN 17.A O no hydrogen 3.217 N/A ILE 67.A N GLN 66.A OE1 no hydrogen 2.887 N/A ARG 68.A N.A ALA 83.A O no hydrogen 2.860 N/A ARG 68.A N.B ALA 83.A O no hydrogen 2.823 N/A ARG 68.A NE.B TRP 110.A O no hydrogen 2.819 N/A ARG 68.A NH2.B TRP 110.A O no hydrogen 2.954 N/A ALA 71.A N LEU 81.A O no hydrogen 2.929 N/A TYR 75.A N SER 73.A OG.A no hydrogen 2.783 N/A TYR 75.A OH LEU 116.A O no hydrogen 3.028 N/A TYR 75.A OH ASP 117.A O no hydrogen 2.888 N/A LEU 76.A N SER 73.A OG.B no hydrogen 2.779 N/A LEU 79.A N LEU 76.A O no hydrogen 3.149 N/A LEU 80.A N THR 92.A O no hydrogen 2.714 N/A LEU 81.A N ALA 71.A O no hydrogen 2.813 N/A SER 82.A N LYS 90.A O no hydrogen 2.903 N/A SER 82.A OG HIS 63.A NE2 no hydrogen 2.728 N/A SER 82.A OG LYS 90.A O no hydrogen 3.484 N/A ALA 83.A N GLY 69.A O no hydrogen 3.154 N/A SER 84.A N THR 88.A O no hydrogen 3.025 N/A SER 84.A OG LYS 65.A O no hydrogen 2.946 N/A SER 84.A OG GLN 66.A O no hydrogen 3.040 N/A LEU 85.A N GLN 66.A O no hydrogen 3.172 N/A ASP 86.A N SER 84.A OG no hydrogen 2.994 N/A ASN 87.A N SER 84.A O no hydrogen 3.218 N/A THR 88.A N ASP 86.A OD1 no hydrogen 2.949 N/A THR 88.A OG1 ASP 86.A OD1 no hydrogen 2.666 N/A THR 88.A OG1 ASP 86.A OD2 no hydrogen 3.429 N/A ILE 89.A N TYR 103.A O no hydrogen 3.067 N/A LYS 90.A N SER 82.A O no hydrogen 3.020 N/A LYS 90.A NZ THR 102.A OG1 no hydrogen 3.196 N/A LEU 91.A N GLN 101.A O.A no hydrogen 2.906 N/A LEU 91.A N GLN 101.A O.B no hydrogen 3.010 N/A THR 92.A N LEU 80.A O no hydrogen 2.857 N/A SER 93.A N THR 98.A O no hydrogen 2.958 N/A SER 93.A OG THR 96.A OG1 no hydrogen 3.408 N/A LEU 94.A N GLY 78.A O no hydrogen 2.826 N/A GLU 95.A N SER 93.A OG no hydrogen 3.120 N/A THR 96.A N SER 93.A OG no hydrogen 3.262 N/A THR 96.A OG1 SER 93.A OG no hydrogen 3.408 N/A THR 98.A OG1 VAL 99.A O no hydrogen 3.440 N/A VAL 100.A N LEU 91.A O no hydrogen 2.765 N/A GLN 101.A N.A LEU 91.A O no hydrogen 3.290 N/A GLN 101.A N.B LEU 91.A O no hydrogen 3.264 N/A GLN 101.A NE2.B THR 139.A O no hydrogen 2.955 N/A TYR 103.A N ILE 89.A O no hydrogen 2.800 N/A TYR 103.A OH ASN 138.A O no hydrogen 2.677 N/A ALA 105.A N ASN 87.A O no hydrogen 2.727 N/A GLY 106.A N ASN 104.A OD1 no hydrogen 3.030 N/A VAL 109.A N SER 84.A O no hydrogen 3.055 N/A TRP 110.A N GLY 125.A O no hydrogen 2.797 N/A SER 111.A OG LEU 155.A O no hydrogen 2.851 N/A CYS 113.A N TYR 123.A O no hydrogen 3.036 N/A CYS 113.A SG TRP 114.A O no hydrogen 3.858 N/A TRP 114.A NE1 ALA 71.A O no hydrogen 2.968 N/A CYS 115.A N TYR 121.A O no hydrogen 2.928 N/A CYS 115.A SG TYR 160.A OH no hydrogen 3.655 N/A CYS 115.A SG GLN 187.A OE1 no hydrogen 3.963 N/A ALA 119.A N ASP 117.A O no hydrogen 2.922 N/A ILE 122.A N TYR 134.A O no hydrogen 2.774 N/A TYR 123.A N CYS 113.A O no hydrogen 2.863 N/A TYR 123.A OH HIS 193.A NE2 no hydrogen 2.776 N/A ALA 124.A N LEU 132.A O no hydrogen 2.797 N/A GLY 125.A N SER 111.A O no hydrogen 2.930 N/A LEU 126.A N SER 130.A O no hydrogen 2.923 N/A ALA 127.A N PRO 108.A O no hydrogen 3.005 N/A GLY 129.A N LEU 126.A O no hydrogen 3.076 N/A SER 130.A N ASN 128.A OD1 no hydrogen 3.082 N/A SER 130.A OG GLU 145.A OE2 no hydrogen 2.748 N/A ILE 131.A N LEU 146.A O no hydrogen 2.968 N/A LEU 132.A N ALA 124.A O no hydrogen 2.826 N/A VAL 133.A N GLN 144.A O no hydrogen 2.926 N/A TYR 134.A N ILE 122.A O no hydrogen 2.825 N/A VAL 136.A N ASN 120.A O no hydrogen 3.138 N/A ARG 137.A N ASP 135.A OD1 no hydrogen 3.088 N/A ARG 137.A NE ASP 135.A OD1 no hydrogen 3.232 N/A ARG 137.A NE ASP 135.A OD2 no hydrogen 3.038 N/A ARG 137.A NH2 ASP 135.A OD2 no hydrogen 2.723 N/A ASN 138.A N ASP 135.A O no hydrogen 2.882 N/A SER 140.A N.A ASN 138.A OD1 no hydrogen 2.979 N/A SER 140.A N.B ASN 138.A OD1 no hydrogen 2.961 N/A SER 140.A OG.A ASN 138.A OD1 no hydrogen 3.048 N/A SER 141.A N ASN 138.A OD1 no hydrogen 3.114 N/A VAL 143.A N VAL 133.A O no hydrogen 2.845 N/A GLN 144.A N VAL 133.A O no hydrogen 3.453 N/A GLN 144.A NE2 PHE 191.A O no hydrogen 2.882 N/A LEU 146.A N ILE 131.A O no hydrogen 2.767 N/A CYS 153.A SG THR 178.A OG1 no hydrogen 3.712 N/A CYS 153.A SG GLU 180.A OE2 no hydrogen 3.656 N/A LEU 155.A N LEU 126.A O no hydrogen 2.991 N/A VAL 156.A N GLY 177.A O no hydrogen 2.986 N/A SER 157.A N GLY 177.A O no hydrogen 3.259 N/A SER 159.A N LEU 175.A O no hydrogen 3.021 N/A SER 159.A OG THR 210.A OG1 no hydrogen 2.944 N/A TYR 160.A OH ASP 117.A OD2 no hydrogen 2.612 N/A MET 161.A N GLY 173.A O no hydrogen 2.844 N/A ARG 163.A N ASP 117.A OD1 no hydrogen 2.884 N/A ALA 164.A N PRO 170.A O no hydrogen 2.943 N/A SER 166.A OG PHE 169.A O no hydrogen 2.774 N/A GLY 173.A N MET 161.A O no hydrogen 2.869 N/A VAL 174.A N TRP 185.A O no hydrogen 2.904 N/A LEU 175.A N SER 159.A O no hydrogen 2.784 N/A ALA 176.A N SER 183.A O no hydrogen 2.874 N/A GLY 177.A N SER 157.A O no hydrogen 2.923 N/A THR 178.A N ASP 181.A O no hydrogen 2.885 N/A LEU 179.A N PRO 154.A O no hydrogen 3.300 N/A GLU 180.A N THR 178.A OG1 no hydrogen 3.214 N/A ASP 181.A N THR 178.A O no hydrogen 3.489 N/A SER 183.A N ALA 176.A O no hydrogen 2.903 N/A SER 183.A OG ASP 181.A OD1 no hydrogen 3.356 N/A PHE 184.A N HIS 196.A O no hydrogen 2.797 N/A TRP 185.A N VAL 174.A O no hydrogen 2.875 N/A GLU 186.A N TRP 194.A O no hydrogen 2.865 N/A GLN 187.A N GLY 172.A O no hydrogen 2.935 N/A GLN 187.A NE2 HIS 193.A NE2 no hydrogen 3.197 N/A LYS 188.A N SER 192.A O no hydrogen 2.908 N/A LYS 188.A NZ GLU 186.A OE1 no hydrogen 3.450 N/A LYS 188.A NZ GLU 186.A OE2 no hydrogen 2.918 N/A LYS 188.A NZ ASN 246.A OD1 no hydrogen 3.212 N/A PHE 191.A N LYS 188.A O no hydrogen 2.818 N/A SER 192.A N ASP 190.A OD1 no hydrogen 3.118 N/A SER 192.A OG ASP 190.A OD1 no hydrogen 2.718 N/A HIS 193.A ND1 GLN 144.A OE1 no hydrogen 2.858 N/A HIS 193.A NE2 TYR 123.A OH no hydrogen 2.776 N/A TRP 194.A N GLU 186.A O no hydrogen 2.915 N/A HIS 196.A N PHE 184.A O no hydrogen 2.777 N/A HIS 196.A NE2 GLU 186.A OE1 no hydrogen 2.787 N/A LEU 198.A N ALA 182.A O no hydrogen 2.931 N/A LEU 200.A N LEU 198.A O no hydrogen 2.758 N/A GLY 203.A N ARG 222.A O no hydrogen 2.700 N/A GLY 204.A N LEU 179.A O no hydrogen 2.887 N/A ASP 207.A N THR 220.A O no hydrogen 2.741 N/A PHE 208.A N SER 157.A OG no hydrogen 2.879 N/A GLN 209.A N LEU 218.A O no hydrogen 2.824 N/A GLN 209.A NE2 ASP 207.A OD1 no hydrogen 2.903 N/A THR 210.A OG1 SER 159.A OG no hydrogen 2.944 N/A GLU 211.A N HIS 216.A O no hydrogen 3.069 N/A SER 213.A OG GLU 211.A OE2 no hydrogen 3.531 N/A SER 213.A OG GLN 272.A OE1 no hydrogen 3.012 N/A SER 214.A N GLU 211.A OE1 no hydrogen 2.991 N/A SER 214.A OG GLU 211.A O no hydrogen 3.508 N/A SER 214.A OG GLU 211.A OE1 no hydrogen 2.810 N/A ARG 215.A N ASN 212.A O no hydrogen 3.397 N/A ARG 215.A NE PHE 169.A O no hydrogen 2.790 N/A ARG 215.A NH1 PRO 162.A O no hydrogen 2.794 N/A ARG 215.A NH1 ASN 212.A O no hydrogen 3.238 N/A ARG 215.A NH2 PRO 162.A O no hydrogen 2.822 N/A ARG 215.A NH2 PHE 169.A O no hydrogen 2.832 N/A HIS 216.A ND1 MET 235.A O no hydrogen 3.179 N/A CYS 217.A N MET 235.A O no hydrogen 3.017 N/A LEU 218.A N GLN 209.A O no hydrogen 2.773 N/A VAL 219.A N VAL 233.A O no hydrogen 2.923 N/A THR 220.A N ASP 207.A O no hydrogen 2.845 N/A THR 220.A OG1 SER 232.A OG no hydrogen 2.712 N/A TYR 221.A N ARG 231.A O.A no hydrogen 2.936 N/A TYR 221.A N ARG 231.A O.B no hydrogen 2.962 N/A ARG 222.A N CYS 205.A O no hydrogen 3.393 N/A ARG 222.A NH1 GLY 203.A O no hydrogen 2.713 N/A ARG 222.A NH2 LYS 225.A O no hydrogen 2.730 N/A ASP 224.A N GLU 201.A O no hydrogen 2.833 N/A LYS 225.A N PRO 223.A O no hydrogen 2.886 N/A THR 228.A OG1 THR 229.A O no hydrogen 3.514 N/A THR 229.A N THR 228.A OG1 no hydrogen 2.615 N/A THR 229.A OG1 ILE 230.A O no hydrogen 3.536 N/A THR 229.A OG1 GLY 259.A O no hydrogen 3.094 N/A THR 229.A OG1 GLY 260.A O no hydrogen 2.369 N/A ILE 230.A N GLY 260.A O no hydrogen 2.717 N/A ARG 231.A N.A TYR 221.A O no hydrogen 3.042 N/A ARG 231.A N.B TYR 221.A O no hydrogen 3.051 N/A ARG 231.A NE.B THR 229.A O no hydrogen 2.748 N/A ARG 231.A NH1.B THR 229.A O no hydrogen 3.129 N/A SER 232.A N PHE 257.A O no hydrogen 2.881 N/A SER 232.A OG THR 220.A OG1 no hydrogen 2.712 N/A VAL 233.A N VAL 219.A O no hydrogen 2.808 N/A LEU 234.A N HIS 255.A O no hydrogen 2.829 N/A MET 235.A N CYS 217.A O no hydrogen 2.737 N/A GLU 236.A N GLN 252.A O no hydrogen 2.884 N/A MET 237.A N ARG 215.A O no hydrogen 3.316 N/A SER 238.A N SER 250.A O no hydrogen 3.008 N/A SER 238.A OG GLN 252.A OE1 no hydrogen 3.212 N/A ARG 240.A N ILE 248.A O no hydrogen 3.073 N/A ASP 242.A N ASN 246.A O no hydrogen 2.716 N/A THR 244.A N ASP 242.A OD1 no hydrogen 3.040 N/A GLY 245.A N ASP 242.A O no hydrogen 3.122 N/A ASN 246.A N ASP 242.A OD1 no hydrogen 2.916 N/A ILE 248.A N ARG 240.A O no hydrogen 2.659 N/A CYS 249.A N HIS 196.A ND1 no hydrogen 3.065 N/A SER 250.A N SER 238.A O no hydrogen 2.850 N/A GLN 252.A N GLU 236.A O no hydrogen 2.935 N/A VAL 254.A N LEU 234.A O no hydrogen 2.744 N/A HIS 255.A NE2 ALA 294.A O no hydrogen 2.782 N/A PHE 257.A N SER 232.A O no hydrogen 2.842 N/A GLY 259.A N ILE 230.A O no hydrogen 2.870 N/A THR 266.A OG1 VAL 309.A O no hydrogen 2.837 N/A LYS 267.A N LEU 310.A O no hydrogen 3.005 N/A ASN 268.A N ASP 207.A OD2 no hydrogen 3.147 N/A ASN 268.A ND2 THR 220.A OG1 no hydrogen 3.023 N/A ALA 269.A N CYS 283.A O no hydrogen 3.163 N/A PHE 271.A N LEU 281.A O no hydrogen 3.083 N/A SER 273.A N ASN 279.A O no hydrogen 2.845 N/A GLU 275.A N SER 273.A OG no hydrogen 3.324 N/A ASN 276.A N SER 273.A O no hydrogen 3.138 N/A ASN 279.A N ASP 277.A OD1 no hydrogen 3.119 N/A ASN 279.A ND2 ASP 277.A OD2 no hydrogen 2.994 N/A LEU 281.A N PHE 271.A O no hydrogen 2.802 N/A VAL 282.A N TRP 292.A O no hydrogen 2.888 N/A CYS 283.A N ALA 269.A O no hydrogen 2.948 N/A CYS 283.A SG LEU 290.A O no hydrogen 3.587 N/A THR 284.A N LEU 290.A O no hydrogen 2.743 N/A GLY 285.A N ASN 268.A OD1 no hydrogen 2.729 N/A SER 288.A OG ASP 302.A OD1 no hydrogen 2.194 N/A SER 288.A OG LEU 303.A O no hydrogen 3.432 N/A ALA 289.A N LEU 303.A O no hydrogen 3.053 N/A LEU 290.A N THR 284.A O no hydrogen 2.814 N/A LEU 291.A N GLN 301.A O no hydrogen 2.876 N/A TRP 292.A N VAL 282.A O no hydrogen 2.593 N/A TRP 292.A NE1 THR 284.A OG1 no hydrogen 3.210 N/A ASP 293.A N SER 298.A O no hydrogen 2.908 N/A ALA 294.A N ILE 280.A O no hydrogen 2.939 N/A SER 296.A N ASP 293.A OD2 no hydrogen 2.941 N/A SER 296.A OG ASP 293.A OD2 no hydrogen 2.707 N/A SER 296.A OG SER 298.A OG no hydrogen 2.870 N/A GLY 297.A N ASP 293.A O no hydrogen 2.785 N/A SER 298.A N SER 296.A OG no hydrogen 3.161 N/A SER 298.A OG SER 296.A OG no hydrogen 2.870 N/A LEU 300.A N LEU 291.A O no hydrogen 2.818 N/A GLN 301.A N LEU 291.A O no hydrogen 3.224 N/A GLN 301.A NE2 TYR 4.A O no hydrogen 2.806 N/A LEU 303.A N ALA 289.A O no hydrogen 2.878 N/A THR 305.A N ASN 287.A O no hydrogen 3.030 N/A THR 305.A OG1 ASN 287.A O no hydrogen 3.208 N/A THR 305.A OG1 GLN 307.A O no hydrogen 2.902 N/A GLN 307.A NE2 ASP 306.A O no hydrogen 2.870 N/A LEU 310.A N LEU 326.A O no hydrogen 2.757 N/A ILE 312.A N LYS 267.A O no hydrogen 3.313 N/A ILE 312.A N ASP 311.A OD1 no hydrogen 2.813 N/A CYS 313.A N ALA 324.A O no hydrogen 2.863 N/A CYS 313.A SG PRO 314.A O no hydrogen 3.821 N/A PHE 315.A N TYR 322.A O no hydrogen 3.069 N/A VAL 317.A N ASN 320.A O no hydrogen 3.014 N/A ASN 320.A N VAL 317.A O no hydrogen 3.222 N/A TYR 322.A N PHE 315.A O no hydrogen 2.839 N/A LEU 323.A N TYR 334.A O no hydrogen 2.863 N/A ALA 324.A N CYS 313.A O no hydrogen 2.905 N/A THR 325.A N HIS 332.A O no hydrogen 2.948 N/A LEU 326.A N ASP 311.A O no hydrogen 2.865 N/A THR 327.A N MET 330.A O no hydrogen 2.774 N/A THR 327.A OG1 MET 330.A O no hydrogen 3.206 N/A LYS 329.A NZ GLN 14.A O no hydrogen 2.593 N/A MET 330.A N THR 327.A OG1 no hydrogen 3.232 N/A VAL 331.A N PHE 10.A O no hydrogen 3.028 N/A HIS 332.A N THR 325.A O no hydrogen 2.790 N/A HIS 332.A ND1 THR 9.A OG1 no hydrogen 2.775 N/A ILE 333.A N LYS 8.A O no hydrogen 2.870 N/A TYR 334.A N LEU 323.A O no hydrogen 2.785 N/A LYS 335.A N HIS 5.A O no hydrogen 2.837 N/A TRP 336.A N SER 321.A O no hydrogen 2.882 N/A TRP 336.A NE1 GLU 275.A OE2 no hydrogen 2.867 N/A GLU 337.A N LYS 3.A O no hydrogen 2.830 N/A