Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6cw6_D.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 4.A N ASN 23.A O no hydrogen 2.870 N/A THR 4.A OG1 ASN 23.A O no hydrogen 2.968 N/A GLN 5.A NE2 TYR 88.A O no hydrogen 3.044 N/A SER 6.A N SER 21.A O no hydrogen 2.997 N/A ARG 8.A NE GLY 104.A O no hydrogen 2.820 N/A ASN 9.A ND2 GLU 152.A OE2 no hydrogen 3.547 N/A LYS 10.A N ARG 106.A O no hydrogen 2.900 N/A ALA 12.A N LEU 108.A O no hydrogen 2.972 N/A THR 14.A N LEU 110.A O no hydrogen 2.875 N/A THR 14.A OG1 LEU 110.A O no hydrogen 3.006 N/A THR 14.A OG1 GLU 111.A OE1 no hydrogen 3.305 N/A GLY 15.A N ALA 80.A O no hydrogen 3.152 N/A GLY 16.A N VAL 13.A O no hydrogen 2.896 N/A VAL 18.A N LEU 77.A O no hydrogen 3.081 N/A LEU 20.A N LEU 75.A O no hydrogen 2.814 N/A SER 21.A N SER 6.A O no hydrogen 2.882 N/A CYS 22.A SG THR 4.A O no hydrogen 3.642 N/A ASN 23.A N THR 4.A O no hydrogen 2.916 N/A GLN 24.A N GLU 71.A O no hydrogen 3.011 N/A GLN 24.A NE2 HIS 28.A O no hydrogen 3.337 N/A GLN 24.A NE2 GLN 70.A O no hydrogen 3.061 N/A ASN 26.A ND2 ALA 2.A O no hydrogen 3.381 N/A HIS 28.A N GLN 24.A OE1 no hydrogen 2.727 N/A HIS 28.A ND1 SER 92.A OG no hydrogen 2.723 N/A ASN 30.A N GLY 93.A O no hydrogen 3.080 N/A ASN 30.A ND2 GLY 93.A O no hydrogen 3.261 N/A ASN 30.A ND2 ASP 94.A O no hydrogen 3.005 N/A MET 31.A N SER 48.A O no hydrogen 2.943 N/A TYR 32.A N ALA 91.A O no hydrogen 2.734 N/A TRP 33.A N HIS 46.A O no hydrogen 2.899 N/A TRP 33.A NE1 PHE 73.A O no hydrogen 3.089 N/A TYR 34.A N PHE 89.A O no hydrogen 2.795 N/A TYR 34.A OH GLN 99.A OE1 no hydrogen 2.538 N/A ARG 35.A N ARG 43.A O no hydrogen 3.206 N/A ARG 35.A NE ASP 37.A OD2 no hydrogen 3.012 N/A ARG 35.A NH1 SER 83.A O no hydrogen 3.358 N/A ARG 35.A NH2 ASP 37.A OD1 no hydrogen 2.885 N/A ARG 35.A NH2 SER 83.A O no hydrogen 2.767 N/A GLN 36.A N VAL 87.A O no hydrogen 2.827 N/A HIS 40.A N ASP 37.A O no hydrogen 2.912 N/A ARG 43.A N ARG 35.A O no hydrogen 3.218 N/A ARG 43.A NH2 ASP 37.A OD2 no hydrogen 2.844 N/A ILE 45.A N TRP 33.A O no hydrogen 2.775 N/A HIS 46.A NE2 TYR 63.A O no hydrogen 2.741 N/A TYR 47.A N GLU 55.A O no hydrogen 3.004 N/A SER 48.A N MET 31.A O no hydrogen 2.821 N/A SER 48.A OG SER 53.A O no hydrogen 2.646 N/A GLY 50.A N SER 48.A OG no hydrogen 3.270 N/A GLY 52.A N ARG 67.A O no hydrogen 2.879 N/A SER 53.A N GLY 50.A O no hydrogen 2.908 N/A GLU 55.A N TYR 47.A O no hydrogen 2.735 N/A GLY 57.A N ILE 45.A O no hydrogen 2.700 N/A ASP 58.A N LEU 44.A O no hydrogen 2.809 N/A ILE 59.A N LEU 44.A O no hydrogen 3.136 N/A TYR 63.A N PRO 60.A O no hydrogen 3.049 N/A TYR 63.A OH TYR 88.A OH no hydrogen 2.531 N/A LYS 64.A N ILE 76.A O no hydrogen 2.833 N/A SER 66.A N SER 74.A O no hydrogen 2.967 N/A ARG 67.A NH1 ASN 29.A O no hydrogen 2.807 N/A ARG 67.A NH1 SER 48.A OG no hydrogen 3.074 N/A ARG 67.A NH2 HIS 28.A O no hydrogen 3.400 N/A ARG 67.A NH2 ASN 29.A O no hydrogen 3.236 N/A ARG 67.A NH2 GLN 70.A O no hydrogen 2.746 N/A GLN 70.A NE2 ASN 27.A O no hydrogen 3.218 N/A GLN 70.A NE2 ASN 27.A OD1 no hydrogen 3.266 N/A GLN 70.A NE2 ASN 29.A OD1 no hydrogen 2.975 N/A ASN 72.A N SER 69.A OG no hydrogen 3.372 N/A PHE 73.A N CYS 22.A O no hydrogen 3.095 N/A SER 74.A N SER 66.A O no hydrogen 2.870 N/A SER 74.A OG LEU 20.A O no hydrogen 3.373 N/A LEU 75.A N LEU 20.A O no hydrogen 2.661 N/A ILE 76.A N LYS 64.A O no hydrogen 2.771 N/A LEU 77.A N VAL 18.A O no hydrogen 2.897 N/A ALA 80.A N GLY 16.A O no hydrogen 2.998 N/A THR 81.A N GLN 84.A OE1 no hydrogen 3.115 N/A THR 81.A OG1 SER 83.A OG no hydrogen 2.654 N/A SER 83.A OG THR 81.A OG1 no hydrogen 2.654 N/A GLN 84.A N THR 81.A O no hydrogen 3.006 N/A GLN 84.A NE2 GLY 62.A O no hydrogen 3.173 N/A THR 85.A N PRO 82.A O no hydrogen 2.970 N/A THR 85.A OG1 PRO 82.A O no hydrogen 2.960 N/A SER 86.A N LEU 107.A O no hydrogen 3.130 N/A SER 86.A OG GLN 36.A O no hydrogen 3.026 N/A SER 86.A OG ASP 37.A OD1 no hydrogen 2.786 N/A VAL 87.A N GLN 36.A O no hydrogen 3.454 N/A TYR 88.A N THR 105.A O no hydrogen 2.709 N/A TYR 88.A OH TYR 63.A OH no hydrogen 2.531 N/A TYR 88.A OH GLN 84.A O no hydrogen 2.581 N/A PHE 89.A N TYR 34.A O no hydrogen 2.918 N/A CYS 90.A N GLN 5.A OE1 no hydrogen 3.241 N/A CYS 90.A SG TYR 32.A O no hydrogen 3.879 N/A CYS 90.A SG ALA 91.A O no hydrogen 3.930 N/A ALA 91.A N TYR 32.A O no hydrogen 2.807 N/A SER 92.A N TYR 100.A O no hydrogen 3.058 N/A SER 92.A OG HIS 28.A ND1 no hydrogen 2.723 N/A GLY 93.A N ASN 30.A O no hydrogen 2.887 N/A GLU 95.A N GLU 95.A OE1 no hydrogen 2.766 N/A GLY 96.A N ASP 94.A OD1 no hydrogen 2.933 N/A TYR 100.A N SER 92.A O no hydrogen 2.860 N/A GLY 102.A N CYS 90.A O no hydrogen 2.833 N/A GLY 104.A N GLN 5.A OE1 no hydrogen 3.022 N/A THR 105.A N TYR 88.A O no hydrogen 2.817 N/A THR 105.A OG1 PRO 7.A O no hydrogen 2.679 N/A ARG 106.A N ARG 8.A O no hydrogen 3.021 N/A LEU 107.A N SER 86.A O no hydrogen 2.987 N/A LEU 108.A N LYS 10.A O no hydrogen 2.966 N/A VAL 109.A N THR 85.A OG1 no hydrogen 2.981 N/A LEU 110.A N ALA 12.A O no hydrogen 2.772 N/A LEU 113.A N ASP 112.A OD1 no hydrogen 2.969 N/A ASN 115.A ND2 ASP 181.A OD2 no hydrogen 3.164 N/A VAL 116.A N LEU 113.A O no hydrogen 3.197 N/A THR 117.A N TYR 147.A O no hydrogen 2.903 N/A LYS 120.A N THR 144.A O no hydrogen 2.818 N/A SER 122.A N LEU 142.A O no hydrogen 2.965 N/A PHE 124.A N VAL 140.A O no hydrogen 2.561 N/A ALA 129.A N SER 127.A OG no hydrogen 3.104 N/A GLU 130.A N SER 127.A OG no hydrogen 3.273 N/A ILE 131.A N SER 127.A O no hydrogen 3.210 N/A SER 132.A N LYS 128.A O no hydrogen 3.402 N/A SER 132.A OG LYS 128.A O no hydrogen 3.309 N/A SER 132.A OG ALA 129.A O no hydrogen 3.009 N/A HIS 133.A N ALA 129.A O no hydrogen 2.822 N/A THR 134.A N GLU 130.A O no hydrogen 2.859 N/A THR 134.A OG1 GLU 130.A O no hydrogen 2.716 N/A GLN 135.A N ILE 131.A O no hydrogen 2.798 N/A GLN 135.A NE2 SER 132.A O no hydrogen 3.477 N/A LYS 136.A N THR 134.A OG1 no hydrogen 3.096 N/A ALA 137.A N VAL 192.A O no hydrogen 2.813 N/A THR 138.A N GLU 130.A OE1 no hydrogen 2.982 N/A THR 138.A OG1 GLU 130.A OE1 no hydrogen 3.298 N/A THR 138.A OG1 GLU 130.A OE2 no hydrogen 2.602 N/A LEU 139.A N LEU 190.A O no hydrogen 2.955 N/A VAL 140.A N PHE 124.A O no hydrogen 2.963 N/A CYS 141.A N SER 188.A O no hydrogen 2.919 N/A CYS 141.A SG SER 122.A O no hydrogen 3.994 N/A LEU 142.A N SER 122.A O no hydrogen 2.882 N/A ALA 143.A N LEU 186.A O no hydrogen 2.830 N/A THR 144.A N LYS 120.A O no hydrogen 2.927 N/A THR 144.A OG1 LYS 120.A O no hydrogen 3.393 N/A GLY 145.A N GLU 175.A OE2 no hydrogen 2.918 N/A PHE 146.A N TYR 184.A O no hydrogen 3.209 N/A TYR 147.A N THR 117.A O no hydrogen 3.017 N/A HIS 150.A ND1 ASN 9.A OD1 no hydrogen 2.616 N/A VAL 151.A N ASP 149.A O no hydrogen 2.925 N/A GLU 152.A N GLN 209.A O no hydrogen 3.054 N/A SER 154.A N GLN 207.A O no hydrogen 2.859 N/A TRP 155.A NE1 SER 188.A OG no hydrogen 3.097 N/A TRP 156.A N ARG 205.A O no hydrogen 2.830 N/A TRP 156.A NE1 SER 154.A OG no hydrogen 2.856 N/A VAL 157.A N LYS 160.A O no hydrogen 2.860 N/A ASN 158.A N HIS 203.A O no hydrogen 3.070 N/A ASN 158.A ND2 ASN 202.A OD1 no hydrogen 3.098 N/A LYS 160.A N VAL 157.A O no hydrogen 3.192 N/A VAL 162.A N TRP 155.A O no hydrogen 2.950 N/A VAL 166.A N HIS 163.A O no hydrogen 3.187 N/A CYS 167.A N ARG 189.A O no hydrogen 3.163 N/A THR 168.A OG1 SER 188.A OG no hydrogen 2.742 N/A ASP 169.A N SER 187.A O no hydrogen 3.265 N/A GLU 175.A N ARG 183.A O no hydrogen 2.816 N/A GLN 176.A N SER 182.A OG no hydrogen 2.968 N/A SER 182.A OG ARG 183.A O no hydrogen 2.804 N/A TYR 184.A N PHE 146.A O no hydrogen 2.661 N/A SER 185.A N LEU 173.A O no hydrogen 2.932 N/A SER 185.A OG GLU 175.A OE2 no hydrogen 2.441 N/A LEU 186.A N ALA 143.A O no hydrogen 2.727 N/A SER 187.A N ASP 169.A OD2 no hydrogen 2.783 N/A SER 187.A OG ASP 169.A OD1 no hydrogen 2.881 N/A SER 187.A OG ASP 169.A OD2 no hydrogen 2.824 N/A SER 188.A N CYS 141.A O no hydrogen 2.910 N/A SER 188.A OG CYS 167.A O no hydrogen 3.282 N/A SER 188.A OG THR 168.A OG1 no hydrogen 2.742 N/A ARG 189.A N CYS 167.A O no hydrogen 3.057 N/A ARG 189.A NH1 CYS 167.A O no hydrogen 3.352 N/A ARG 189.A NH1 ASP 169.A OD1 no hydrogen 2.987 N/A ARG 189.A NH2 ASP 169.A OD1 no hydrogen 3.107 N/A LEU 190.A N LEU 139.A O no hydrogen 3.188 N/A ARG 191.A N GLY 165.A O no hydrogen 2.873 N/A ARG 191.A NE GLU 130.A OE2 no hydrogen 3.234 N/A ARG 191.A NH1 GLU 130.A OE2 no hydrogen 3.244 N/A VAL 192.A N ALA 137.A O no hydrogen 2.836 N/A SER 193.A OG THR 195.A OG1 no hydrogen 3.368 N/A ALA 194.A N GLN 135.A O no hydrogen 3.016 N/A THR 195.A OG1 SER 193.A OG no hydrogen 3.368 N/A PHE 196.A N SER 193.A O no hydrogen 2.918 N/A PHE 196.A N SER 193.A OG no hydrogen 3.203 N/A TRP 197.A N SER 193.A O no hydrogen 3.127 N/A GLN 198.A N ALA 194.A O no hydrogen 2.859 N/A ASN 199.A N PHE 196.A O no hydrogen 3.336 N/A ARG 201.A N ASN 199.A OD1 no hydrogen 3.087 N/A ASN 202.A N ASN 199.A O no hydrogen 3.273 N/A ASN 202.A ND2 PHE 196.A O no hydrogen 2.949 N/A HIS 203.A N ASN 158.A OD1 no hydrogen 2.799 N/A PHE 204.A N ALA 235.A O no hydrogen 2.718 N/A ARG 205.A N TRP 156.A O no hydrogen 2.875 N/A ARG 205.A NH2 SER 232.A OG no hydrogen 2.624 N/A CYS 206.A N ALA 233.A O no hydrogen 2.764 N/A GLN 207.A N SER 154.A O no hydrogen 2.925 N/A VAL 208.A N VAL 231.A O no hydrogen 2.696 N/A GLN 209.A N GLU 152.A O no hydrogen 2.969 N/A PHE 210.A N GLN 229.A O no hydrogen 2.786 N/A TYR 211.A N HIS 150.A O no hydrogen 3.146 N/A TYR 211.A OH GLU 152.A OE1 no hydrogen 3.250 N/A GLY 212.A N THR 228.A OG1 no hydrogen 3.060 N/A LEU 213.A N PRO 226.A O no hydrogen 3.066 N/A SER 214.A N ASP 217.A OD2 no hydrogen 2.966 N/A SER 214.A OG ASP 217.A OD2 no hydrogen 3.486 N/A TRP 219.A NE1 ARG 223.A O no hydrogen 2.721 N/A GLN 221.A NE2 ARG 114.A O no hydrogen 2.913 N/A ARG 223.A NE GLN 221.A OE1 no hydrogen 3.275 N/A ARG 223.A NH1 VAL 116.A O no hydrogen 2.672 N/A ARG 223.A NH2 VAL 116.A O no hydrogen 3.019 N/A LYS 225.A NZ SER 214.A O no hydrogen 3.166 N/A LYS 225.A NZ GLU 215.A O no hydrogen 2.780 N/A LYS 225.A NZ ASP 217.A O no hydrogen 2.933 N/A VAL 227.A N LYS 225.A O no hydrogen 2.686 N/A THR 228.A N LEU 213.A O no hydrogen 3.068 N/A THR 228.A OG1 LEU 213.A O no hydrogen 3.457 N/A GLN 229.A N PHE 210.A O no hydrogen 2.972 N/A VAL 231.A N VAL 208.A O no hydrogen 3.009 N/A ALA 233.A N CYS 206.A O no hydrogen 2.805 N/A ALA 235.A N PHE 204.A O no hydrogen 2.925 N/A GLY 237.A N ASN 202.A O no hydrogen 3.185 N/A ARG 238.A N TRP 197.A O no hydrogen 3.092 N/A ARG 238.A NE TRP 236.A O no hydrogen 3.281 N/A ARG 238.A NH2 TRP 236.A O no hydrogen 2.771 N/A