Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6cx7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N CYS 98.A O no hydrogen 3.044 N/A ARG 5.A N TRP 25.A O no hydrogen 2.874 N/A CYS 6.A N ALA 96.A O no hydrogen 2.683 N/A LEU 7.A N VAL 23.A O no hydrogen 2.892 N/A GLN 8.A N LEU 94.A O no hydrogen 2.901 N/A GLN 8.A NE2 SER 10.A OG no hydrogen 3.169 N/A MET 9.A N ASP 21.A O no hydrogen 3.009 N/A SER 10.A N ILE 92.A O no hydrogen 2.780 N/A SER 10.A OG THR 20.A OG1 no hydrogen 2.924 N/A SER 11.A N ARG 19.A O no hydrogen 2.976 N/A SER 11.A OG GLU 91.A OE1 no hydrogen 2.575 N/A PHE 12.A N ILE 90.A O no hydrogen 2.845 N/A ALA 13.A N TRP 17.A O no hydrogen 3.201 N/A SER 16.A N ASN 14.A OD1 no hydrogen 3.357 N/A SER 16.A OG ASN 14.A OD1 no hydrogen 3.325 N/A TRP 17.A N ASN 14.A O no hydrogen 3.494 N/A ARG 19.A N SER 11.A O no hydrogen 3.066 N/A ARG 19.A NE ASP 21.A OD2 no hydrogen 2.798 N/A ARG 19.A NH2 ASP 21.A OD1 no hydrogen 3.271 N/A ARG 19.A NH2 ASP 21.A OD2 no hydrogen 3.430 N/A THR 20.A N ASN 36.A OD1 no hydrogen 2.885 N/A THR 20.A OG1 SER 10.A OG no hydrogen 2.924 N/A ASP 21.A N MET 9.A O no hydrogen 3.043 N/A SER 22.A N TRP 34.A O no hydrogen 2.964 N/A VAL 23.A N LEU 7.A O no hydrogen 3.065 N/A VAL 24.A N HIS 32.A O no hydrogen 2.989 N/A TRP 25.A N ARG 5.A O no hydrogen 2.895 N/A LEU 26.A N LEU 29.A O no hydrogen 2.954 N/A GLY 27.A N THR 3.A O no hydrogen 2.895 N/A LEU 29.A N LEU 26.A O no hydrogen 3.180 N/A GLN 30.A N GLU 233.A OE1 no hydrogen 3.172 N/A GLN 30.A NE2 HIS 32.A O no hydrogen 3.249 N/A THR 31.A N VAL 24.A O no hydrogen 2.815 N/A THR 31.A OG1 VAL 24.A O no hydrogen 3.418 N/A THR 31.A OG1 HIS 32.A ND1 no hydrogen 2.770 N/A HIS 32.A N VAL 24.A O no hydrogen 3.453 N/A HIS 32.A ND1 THR 31.A OG1 no hydrogen 2.770 N/A ARG 33.A N SER 42.A O no hydrogen 3.010 N/A TRP 34.A N SER 22.A O no hydrogen 2.766 N/A TRP 34.A NE1 SER 38.A O no hydrogen 2.859 N/A ASN 36.A N ASP 21.A OD1 no hydrogen 3.072 N/A ASP 37.A N SER 35.A OG no hydrogen 3.144 N/A SER 38.A N SER 35.A O no hydrogen 3.092 N/A SER 38.A OG THR 40.A O no hydrogen 2.581 N/A THR 40.A N SER 38.A OG no hydrogen 3.115 N/A ILE 41.A N GLN 61.A OE1 no hydrogen 2.800 N/A SER 42.A N ARG 33.A O no hydrogen 2.822 N/A THR 44.A N THR 31.A O no hydrogen 3.210 N/A THR 44.A OG1 GLN 30.A O no hydrogen 2.721 N/A LYS 45.A N SER 48.A OG no hydrogen 3.149 N/A LYS 45.A NZ GLN 30.A O no hydrogen 3.003 N/A LYS 45.A NZ GLU 233.A OE2 no hydrogen 2.680 N/A SER 48.A N LYS 45.A O no hydrogen 3.420 N/A SER 48.A OG THR 31.A O no hydrogen 2.621 N/A SER 48.A OG LYS 45.A O no hydrogen 3.109 N/A GLN 49.A NE2 LEU 52.A O no hydrogen 2.904 N/A GLN 49.A NE2 ASN 54.A OD1 no hydrogen 2.998 N/A GLY 50.A N TRP 47.A O no hydrogen 2.708 N/A LYS 51.A NZ GLU 171.A OE1 no hydrogen 2.906 N/A LEU 52.A N GLN 49.A O no hydrogen 3.259 N/A GLN 56.A N SER 53.A OG no hydrogen 3.316 N/A GLN 56.A NE2 SER 53.A OG no hydrogen 3.119 N/A TRP 57.A N SER 53.A O no hydrogen 2.966 N/A GLU 58.A N ASN 54.A O no hydrogen 3.141 N/A LYS 59.A N GLN 55.A O no hydrogen 3.146 N/A LEU 60.A N GLN 56.A O no hydrogen 3.036 N/A GLN 61.A N TRP 57.A O no hydrogen 2.725 N/A HIS 62.A N GLU 58.A O no hydrogen 2.807 N/A MET 63.A N LYS 59.A O no hydrogen 3.158 N/A PHE 64.A N LEU 60.A O no hydrogen 3.127 N/A GLN 65.A N GLN 61.A O no hydrogen 2.842 N/A GLN 65.A NE2 ALA 39.A O no hydrogen 2.784 N/A VAL 66.A N HIS 62.A O no hydrogen 3.079 N/A TYR 67.A N MET 63.A O no hydrogen 2.954 N/A TYR 67.A OH GLN 8.A OE1 no hydrogen 2.713 N/A ARG 68.A N PHE 64.A O no hydrogen 2.918 N/A ARG 68.A NH1 SER 35.A O no hydrogen 3.145 N/A ARG 68.A NH1 SER 38.A O no hydrogen 3.501 N/A ARG 68.A NH2 SER 38.A O no hydrogen 3.092 N/A SER 70.A N VAL 66.A O no hydrogen 3.112 N/A SER 70.A OG VAL 66.A O no hydrogen 2.958 N/A PHE 71.A N TYR 67.A O no hydrogen 2.662 N/A THR 72.A N ARG 68.A O no hydrogen 3.222 N/A THR 72.A OG1 ARG 68.A O no hydrogen 2.892 N/A ARG 73.A N VAL 69.A O no hydrogen 3.278 N/A ASP 74.A N SER 70.A O no hydrogen 2.896 N/A ILE 75.A N PHE 71.A O no hydrogen 2.977 N/A GLN 76.A N THR 72.A O no hydrogen 3.344 N/A GLU 77.A N ARG 73.A O no hydrogen 2.986 N/A LEU 78.A N ASP 74.A O no hydrogen 2.810 N/A VAL 79.A N ILE 75.A O no hydrogen 2.907 N/A LYS 80.A N GLN 76.A O no hydrogen 3.402 N/A LYS 80.A NZ GLU 77.A OE1 no hydrogen 2.717 N/A MET 81.A N GLU 77.A O no hydrogen 3.039 N/A MET 82.A N LEU 78.A O no hydrogen 3.149 N/A MET 82.A N VAL 79.A O no hydrogen 3.277 N/A SER 83.A N VAL 79.A O no hydrogen 2.969 N/A LYS 85.A N MET 82.A O no hydrogen 3.153 N/A TYR 88.A N ASP 87.A OD1 no hydrogen 2.752 N/A ILE 90.A N PHE 12.A O no hydrogen 2.925 N/A GLU 91.A N GLN 115.A OE1 no hydrogen 3.026 N/A ILE 92.A N SER 10.A O no hydrogen 2.924 N/A GLN 93.A N ALA 113.A O no hydrogen 3.055 N/A LEU 94.A N GLN 8.A O no hydrogen 2.863 N/A SER 95.A N HIS 111.A O no hydrogen 2.895 N/A ALA 96.A N CYS 6.A O no hydrogen 3.139 N/A GLY 97.A N PHE 109.A O no hydrogen 2.980 N/A CYS 98.A N PHE 4.A O no hydrogen 3.330 N/A GLU 99.A N GLU 107.A O no hydrogen 2.896 N/A MET 100.A N TYR 2.A O no hydrogen 3.011 N/A TYR 101.A N ALA 105.A O no hydrogen 3.122 N/A TYR 101.A OH GLU 107.A OE1 no hydrogen 2.670 N/A GLU 107.A N GLU 99.A O no hydrogen 3.364 N/A SER 108.A OG LEU 158.A O no hydrogen 2.653 N/A PHE 109.A N GLY 97.A O no hydrogen 2.865 N/A HIS 111.A N SER 95.A O no hydrogen 2.783 N/A VAL 112.A N VAL 120.A O no hydrogen 2.697 N/A ALA 113.A N GLN 93.A O no hydrogen 2.869 N/A PHE 114.A N LYS 117.A O no hydrogen 2.897 N/A GLN 115.A N GLU 91.A O no hydrogen 3.059 N/A GLN 115.A NE2 PRO 89.A O no hydrogen 3.011 N/A LYS 117.A N PHE 114.A O no hydrogen 3.279 N/A VAL 119.A N VAL 112.A O no hydrogen 3.186 N/A VAL 120.A N VAL 112.A O no hydrogen 3.344 N/A ARG 121.A N GLN 128.A O no hydrogen 2.925 N/A ARG 121.A NE GLN 128.A OE1 no hydrogen 3.015 N/A ARG 121.A NH2 GLN 128.A OE1 no hydrogen 2.938 N/A PHE 122.A N LEU 110.A O no hydrogen 3.088 N/A TRP 123.A N SER 126.A O no hydrogen 2.970 N/A SER 126.A N TRP 123.A O no hydrogen 3.360 N/A TRP 127.A N ASN 145.A OD1 no hydrogen 2.700 N/A GLN 128.A N ARG 121.A O no hydrogen 2.943 N/A VAL 130.A N VAL 119.A O no hydrogen 3.200 N/A ALA 133.A N VAL 130.A O no hydrogen 3.188 N/A ASP 138.A N SER 135.A O no hydrogen 3.170 N/A LEU 139.A N TRP 136.A O no hydrogen 3.322 N/A ILE 141.A N LEU 137.A O no hydrogen 2.995 N/A LYS 142.A N ASP 138.A O no hydrogen 3.003 N/A VAL 143.A N LEU 139.A O no hydrogen 3.059 N/A LEU 144.A N PRO 140.A O no hydrogen 2.903 N/A ASN 145.A N ILE 141.A O no hydrogen 2.889 N/A ASN 145.A ND2 TRP 127.A O no hydrogen 2.949 N/A ALA 146.A N LYS 142.A O no hydrogen 3.160 N/A ASP 147.A N LEU 144.A O no hydrogen 3.283 N/A THR 150.A N ASP 147.A OD1 no hydrogen 3.186 N/A THR 150.A OG1 ASP 147.A OD2 no hydrogen 2.711 N/A SER 151.A N ASP 147.A O no hydrogen 3.209 N/A SER 151.A OG THR 125.A O no hydrogen 2.766 N/A ALA 152.A N GLN 148.A O no hydrogen 3.035 N/A THR 153.A N GLY 149.A O no hydrogen 3.283 N/A THR 153.A OG1 GLY 149.A O no hydrogen 3.050 N/A VAL 154.A N THR 150.A O no hydrogen 2.887 N/A GLN 155.A N SER 151.A O no hydrogen 2.983 N/A GLN 155.A NE2 SER 151.A O no hydrogen 3.453 N/A GLN 155.A NE2 SER 151.A OG no hydrogen 3.074 N/A MET 156.A N ALA 152.A O no hydrogen 3.084 N/A LEU 157.A N THR 153.A O no hydrogen 2.890 N/A LEU 158.A N VAL 154.A O no hydrogen 2.824 N/A ASN 159.A N GLN 155.A O no hydrogen 2.736 N/A ASP 160.A N MET 156.A O no hydrogen 3.042 N/A THR 161.A N MET 156.A O no hydrogen 2.980 N/A THR 161.A OG1 MET 156.A O no hydrogen 3.451 N/A CYS 162.A N LEU 157.A O no hydrogen 2.970 N/A LEU 164.A N ASP 160.A O no hydrogen 3.186 N/A PHE 165.A N THR 161.A O no hydrogen 2.975 N/A VAL 166.A N CYS 162.A O no hydrogen 2.877 N/A ARG 167.A N PRO 163.A O no hydrogen 2.918 N/A ARG 167.A NH2 ALA 105.A O no hydrogen 3.399 N/A GLY 168.A N LEU 164.A O no hydrogen 3.205 N/A LEU 169.A N PHE 165.A O no hydrogen 2.814 N/A LEU 170.A N VAL 166.A O no hydrogen 2.959 N/A GLU 171.A N ARG 167.A O no hydrogen 3.263 N/A ALA 172.A N GLY 168.A O no hydrogen 3.049 N/A GLY 173.A N LEU 169.A O no hydrogen 2.863 N/A LYS 174.A N GLU 171.A O no hydrogen 3.372 N/A LEU 177.A N GLY 173.A O no hydrogen 2.920 N/A GLU 178.A N LYS 174.A O no hydrogen 2.869 N/A GLN 180.A NE2 GLU 178.A O no hydrogen 3.570 N/A GLU 181.A N TYR 204.A O no hydrogen 3.041 N/A VAL 184.A N SER 201.A O no hydrogen 2.908 N/A TRP 186.A N HIS 199.A O no hydrogen 2.894 N/A SER 188.A N VAL 197.A O no hydrogen 3.103 N/A SER 188.A OG HIS 199.A NE2 no hydrogen 2.735 N/A VAL 190.A N GLN 195.A O no hydrogen 3.007 N/A ARG 194.A N VAL 243.A O no hydrogen 3.118 N/A GLN 195.A N VAL 190.A O no hydrogen 2.937 N/A LEU 196.A N LEU 241.A O no hydrogen 2.800 N/A VAL 197.A N SER 188.A O no hydrogen 2.960 N/A CYS 198.A N ALA 239.A O no hydrogen 2.944 N/A HIS 199.A N TRP 186.A O no hydrogen 2.803 N/A HIS 199.A ND1 TYR 236.A OH no hydrogen 2.681 N/A HIS 199.A NE2 SER 188.A OG no hydrogen 2.735 N/A VAL 200.A N LEU 237.A O no hydrogen 2.912 N/A SER 201.A N VAL 184.A O no hydrogen 2.868 N/A GLY 202.A N TRP 235.A O no hydrogen 3.011 N/A TYR 204.A N GLU 181.A O no hydrogen 3.279 N/A TYR 204.A OH ASP 28.A OD1 no hydrogen 2.831 N/A TRP 209.A N LYS 256.A O no hydrogen 3.019 N/A MET 211.A N ARG 254.A O no hydrogen 3.190 N/A TRP 212.A N THR 222.A OG1 no hydrogen 3.285 N/A TRP 212.A NE1 ALA 239.A O no hydrogen 2.823 N/A MET 213.A N ALA 252.A O no hydrogen 2.877 N/A ARG 214.A N GLN 217.A O no hydrogen 3.073 N/A GLN 219.A N TRP 212.A O no hydrogen 2.855 N/A THR 222.A N GLN 219.A O no hydrogen 3.243 N/A THR 222.A OG1 GLN 219.A O no hydrogen 2.636 N/A HIS 223.A N THR 240.A O no hydrogen 2.861 N/A GLY 225.A N GLN 238.A O no hydrogen 2.836 N/A LEU 228.A N TYR 236.A O no hydrogen 2.823 N/A ASN 230.A N THR 234.A O no hydrogen 2.826 N/A ASN 230.A ND2 SER 201.A OG no hydrogen 3.355 N/A ASN 230.A ND2 THR 234.A OG1 no hydrogen 3.062 N/A GLU 233.A N ASN 230.A O no hydrogen 3.220 N/A THR 234.A OG1 ASP 232.A OD1 no hydrogen 2.819 N/A TRP 235.A N PHE 203.A O no hydrogen 3.122 N/A TYR 236.A N LEU 228.A O no hydrogen 2.662 N/A TYR 236.A OH HIS 199.A ND1 no hydrogen 2.681 N/A TYR 236.A OH GLN 238.A OE1 no hydrogen 3.327 N/A LEU 237.A N VAL 200.A O no hydrogen 2.940 N/A ALA 239.A N CYS 198.A O no hydrogen 3.123 N/A THR 240.A N HIS 223.A O no hydrogen 2.964 N/A THR 240.A OG1 HIS 223.A O no hydrogen 3.336 N/A LEU 241.A N LEU 196.A O no hydrogen 2.830 N/A VAL 243.A N ARG 194.A O no hydrogen 3.140 N/A ALA 245.A N GLY 192.A O no hydrogen 3.413 N/A GLY 246.A N GLU 248.A OE1 no hydrogen 2.697 N/A GLU 247.A N GLU 244.A O no hydrogen 3.007 N/A GLU 248.A N GLU 248.A OE1 no hydrogen 3.207 N/A ALA 252.A N MET 213.A O no hydrogen 2.839 N/A CYS 253.A N LEU 267.A O no hydrogen 2.957 N/A ARG 254.A N MET 211.A O no hydrogen 3.064 N/A ARG 254.A NH2 ASP 264.A OD2 no hydrogen 3.568 N/A VAL 255.A N ILE 265.A O no hydrogen 2.983 N/A LYS 256.A N TRP 209.A O no hydrogen 2.889 N/A LYS 256.A NZ ASP 264.A OD2 no hydrogen 3.001 N/A HIS 257.A ND1 PRO 207.A O no hydrogen 3.011 N/A SER 258.A OG GLN 180.A OE1 no hydrogen 2.841 N/A SER 259.A OG GLU 181.A O no hydrogen 3.408 N/A LEU 260.A N HIS 257.A O no hydrogen 3.087 N/A ILE 265.A N VAL 255.A O no hydrogen 3.212 N/A LEU 267.A N CYS 253.A O no hydrogen 3.215 N/A TRP 269.A N LEU 251.A O no hydrogen 2.991 N/A