Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6d43_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A NE ASP 223.A OD1 no hydrogen 3.088 N/A ARG 1.A NE ASP 223.A OD2 no hydrogen 3.045 N/A ARG 1.A NH1 GLN 199.A O no hydrogen 2.728 N/A ARG 1.A NH2 ASP 223.A OD1 no hydrogen 3.331 N/A PHE 3.A N ASP 33.A O no hydrogen 3.186 N/A PHE 4.A N ASP 223.A O no hydrogen 2.949 N/A VAL 5.A N GLU 35.A O no hydrogen 2.815 N/A GLY 6.A N PHE 225.A O no hydrogen 2.752 N/A GLY 7.A N VAL 37.A O no hydrogen 2.684 N/A ASN 8.A N VAL 227.A O no hydrogen 2.809 N/A TRP 9.A N ALA 39.A O no hydrogen 2.997 N/A LYS 10.A N ASN 8.A OD1 no hydrogen 2.982 N/A LYS 10.A NZ GLU 94.A OE2 no hydrogen 2.759 N/A ASN 12.A ND2 TRP 9.A O no hydrogen 2.828 N/A ARG 14.A N SER 17.A OG no hydrogen 3.166 N/A ARG 14.A NH1 GLY 13.A O no hydrogen 2.743 N/A SER 17.A OG ARG 14.A O no hydrogen 3.505 N/A LEU 18.A N ARG 14.A O no hydrogen 2.949 N/A GLY 19.A N LYS 15.A O no hydrogen 2.850 N/A GLU 20.A N GLN 16.A O no hydrogen 3.329 N/A LEU 21.A N SER 17.A O no hydrogen 3.205 N/A ILE 22.A N LEU 18.A O no hydrogen 2.959 N/A GLY 23.A N GLY 19.A O no hydrogen 2.935 N/A THR 24.A N GLU 20.A O no hydrogen 2.950 N/A THR 24.A OG1 GLU 20.A O no hydrogen 3.044 N/A LEU 25.A N LEU 21.A O no hydrogen 2.906 N/A ASN 26.A N ILE 22.A O no hydrogen 2.826 N/A ASN 26.A ND2 LYS 51.A O no hydrogen 3.001 N/A ALA 27.A N GLY 23.A O no hydrogen 3.123 N/A ALA 28.A N LEU 25.A O no hydrogen 3.021 N/A THR 34.A N PRO 31.A O no hydrogen 3.056 N/A THR 34.A OG1 ASP 33.A OD1 no hydrogen 2.974 N/A GLU 35.A N PHE 3.A O no hydrogen 2.710 N/A VAL 37.A N VAL 5.A O no hydrogen 2.958 N/A CYS 38.A N ALA 57.A O no hydrogen 3.010 N/A ALA 39.A N GLY 7.A O no hydrogen 2.737 N/A TYR 44.A N PRO 41.A O no hydrogen 2.749 N/A ALA 48.A N TYR 44.A O no hydrogen 2.832 N/A ARG 49.A N ILE 45.A O no hydrogen 2.962 N/A ARG 49.A NE ARG 49.A O no hydrogen 2.688 N/A ARG 49.A NH1 ILE 56.A O no hydrogen 3.024 N/A ARG 49.A NH2 LEU 52.A O no hydrogen 2.977 N/A ARG 49.A NH2 ASP 53.A O no hydrogen 3.104 N/A ARG 49.A NH2 ILE 56.A O no hydrogen 3.314 N/A GLN 50.A N ASP 46.A O no hydrogen 3.129 N/A GLN 50.A NE2 ASP 46.A OD1 no hydrogen 2.920 N/A LYS 51.A N PHE 47.A O no hydrogen 3.219 N/A LEU 52.A N ALA 48.A O no hydrogen 2.706 N/A ASP 53.A N ASN 26.A OD1 no hydrogen 2.702 N/A LYS 55.A N ASP 53.A OD1 no hydrogen 2.818 N/A LYS 55.A NZ ASN 26.A O no hydrogen 2.705 N/A LYS 55.A NZ ALA 28.A O no hydrogen 2.905 N/A ILE 56.A N ASP 53.A O no hydrogen 3.137 N/A ALA 57.A N VAL 36.A O no hydrogen 3.108 N/A ALA 59.A N CYS 38.A O no hydrogen 2.862 N/A ALA 60.A N TRP 87.A O no hydrogen 3.120 N/A GLN 61.A NE2 LYS 10.A O no hydrogen 2.871 N/A GLN 61.A NE2 ALA 39.A O no hydrogen 3.108 N/A ASN 62.A ND2 GLU 101.A OE2 no hydrogen 3.114 N/A CYS 63.A SG TYR 64.A O no hydrogen 3.384 N/A TYR 64.A N ILE 75.A O no hydrogen 2.787 N/A LYS 65.A NZ GLN 108.A OE1 no hydrogen 2.725 N/A PHE 71.A N GLY 69.A O no hydrogen 2.907 N/A GLU 74.A N PHE 71.A O no hydrogen 2.957 N/A SER 76.A OG THR 67.A O no hydrogen 3.061 N/A MET 79.A N SER 76.A OG no hydrogen 3.281 N/A ILE 80.A N SER 76.A O no hydrogen 3.127 N/A LYS 81.A N PRO 77.A O no hydrogen 2.769 N/A LYS 81.A NZ GLU 116.A O no hydrogen 3.005 N/A ASP 82.A N GLY 78.A O no hydrogen 2.798 N/A CYS 83.A N MET 79.A O no hydrogen 2.941 N/A CYS 83.A SG MET 79.A O no hydrogen 3.424 N/A GLY 84.A N LYS 81.A O no hydrogen 2.792 N/A ALA 85.A N ILE 80.A O no hydrogen 3.141 N/A THR 86.A N VAL 58.A O no hydrogen 2.946 N/A VAL 88.A N GLY 119.A O no hydrogen 2.862 N/A VAL 89.A N ALA 60.A O no hydrogen 2.797 N/A LEU 90.A N ILE 121.A O no hydrogen 2.908 N/A SER 93.A N GLU 162.A OE1 no hydrogen 2.757 N/A SER 93.A OG GLU 162.A OE2 no hydrogen 3.546 N/A GLU 94.A N HIS 92.A ND1 no hydrogen 3.381 N/A ARG 95.A N HIS 92.A O no hydrogen 2.740 N/A ARG 95.A NE GLU 101.A OE2 no hydrogen 2.900 N/A ARG 95.A NH2 GLU 101.A OE2 no hydrogen 3.499 N/A ARG 96.A N HIS 92.A O no hydrogen 3.044 N/A ARG 96.A NE GLY 91.A O no hydrogen 2.825 N/A ARG 96.A NE CYS 123.A O no hydrogen 3.398 N/A ARG 96.A NH1 ASP 103.A OD1 no hydrogen 2.766 N/A ARG 96.A NH2 CYS 123.A O no hydrogen 2.854 N/A HIS 97.A N SER 93.A O no hydrogen 2.705 N/A VAL 98.A N GLU 94.A O no hydrogen 3.193 N/A PHE 99.A N GLU 94.A O no hydrogen 3.294 N/A GLU 101.A N ARG 95.A O no hydrogen 2.893 N/A LEU 105.A N SER 102.A OG no hydrogen 3.035 N/A ILE 106.A N SER 102.A O no hydrogen 3.019 N/A GLY 107.A N ASP 103.A O no hydrogen 2.964 N/A GLN 108.A N GLU 104.A O no hydrogen 3.209 N/A LYS 109.A N LEU 105.A O no hydrogen 2.900 N/A LYS 109.A NZ ASN 62.A OD1 no hydrogen 3.206 N/A LYS 109.A NZ CYS 63.A O no hydrogen 3.013 N/A LYS 109.A NZ GLU 101.A OE1 no hydrogen 2.722 N/A LYS 109.A NZ GLU 101.A OE2 no hydrogen 3.161 N/A VAL 110.A N ILE 106.A O no hydrogen 2.837 N/A ALA 111.A N GLY 107.A O no hydrogen 2.993 N/A HIS 112.A N GLN 108.A O no hydrogen 3.037 N/A ALA 113.A N LYS 109.A O no hydrogen 2.880 N/A LEU 114.A N VAL 110.A O no hydrogen 2.989 N/A ALA 115.A N ALA 111.A O no hydrogen 3.004 N/A GLU 116.A N HIS 112.A O no hydrogen 2.955 N/A GLY 117.A N LEU 114.A O no hydrogen 3.067 N/A LEU 118.A N ALA 113.A O no hydrogen 3.088 N/A GLY 119.A N THR 86.A O no hydrogen 2.980 N/A VAL 120.A N LYS 156.A O no hydrogen 2.952 N/A ILE 121.A N VAL 88.A O no hydrogen 2.893 N/A ALA 122.A N VAL 158.A O no hydrogen 2.864 N/A CYS 123.A N LEU 90.A O no hydrogen 2.824 N/A ILE 124.A N ALA 160.A O no hydrogen 2.913 N/A GLY 125.A N GLN 143.A OE1 no hydrogen 2.799 N/A GLU 126.A N GLU 126.A OE1 no hydrogen 2.820 N/A LYS 127.A N GLU 130.A OE1 no hydrogen 2.819 N/A ARG 131.A N LYS 127.A O no hydrogen 3.074 N/A ARG 131.A NH1 GLU 126.A OE2 no hydrogen 2.416 N/A GLU 132.A N LEU 128.A O no hydrogen 2.888 N/A ALA 133.A N ASP 129.A O no hydrogen 2.968 N/A GLY 134.A N ARG 131.A O no hydrogen 3.072 N/A ILE 135.A N GLU 130.A O no hydrogen 3.042 N/A THR 136.A OG1 GLU 126.A OE2 no hydrogen 2.817 N/A VAL 139.A N ILE 135.A O no hydrogen 3.043 N/A VAL 140.A N THR 136.A O no hydrogen 3.004 N/A PHE 141.A N GLU 137.A O no hydrogen 2.953 N/A GLU 142.A N LYS 138.A O no hydrogen 3.007 N/A GLN 143.A N VAL 139.A O no hydrogen 3.028 N/A GLN 143.A NE2 GLY 125.A O no hydrogen 3.502 N/A THR 144.A N VAL 140.A O no hydrogen 2.860 N/A THR 144.A OG1 VAL 140.A O no hydrogen 2.611 N/A LYS 145.A N PHE 141.A O no hydrogen 2.835 N/A LYS 145.A NZ ASP 149.A OD1 no hydrogen 3.353 N/A LYS 145.A NZ ASP 149.A OD2 no hydrogen 3.541 N/A VAL 146.A N GLU 142.A O no hydrogen 3.105 N/A ILE 147.A N GLN 143.A O no hydrogen 3.327 N/A ALA 148.A N THR 144.A O no hydrogen 2.785 N/A ASP 149.A N LYS 145.A O no hydrogen 2.834 N/A ASN 150.A N ILE 147.A O no hydrogen 2.956 N/A ASN 150.A ND2 VAL 146.A O no hydrogen 2.959 N/A VAL 151.A N ALA 148.A O no hydrogen 3.133 N/A SER 155.A N ASP 153.A OD1 no hydrogen 3.087 N/A SER 155.A OG ASP 153.A OD1 no hydrogen 2.862 N/A SER 155.A OG ASP 153.A OD2 no hydrogen 3.017 N/A LYS 156.A N ASP 153.A O no hydrogen 3.264 N/A LYS 156.A NZ GLY 117.A O no hydrogen 3.436 N/A VAL 157.A N TRP 154.A O no hydrogen 3.028 N/A VAL 158.A N VAL 120.A O no hydrogen 2.931 N/A LEU 159.A N ARG 202.A O no hydrogen 3.044 N/A ALA 160.A N ALA 122.A O no hydrogen 2.796 N/A TYR 161.A N ILE 204.A O no hydrogen 2.878 N/A TYR 161.A OH GLU 126.A OE1 no hydrogen 2.603 N/A GLU 162.A N ILE 124.A O no hydrogen 2.733 N/A TRP 165.A N GLU 126.A O no hydrogen 2.996 N/A TRP 165.A NE1 TYR 161.A OH no hydrogen 3.047 N/A ALA 166.A N PRO 163.A O no hydrogen 2.989 N/A ILE 167.A N VAL 164.A O no hydrogen 3.083 N/A THR 169.A OG1 TRP 165.A O no hydrogen 2.584 N/A LYS 171.A N THR 169.A OG1 no hydrogen 3.140 N/A THR 174.A N GLN 177.A OE1 no hydrogen 2.931 N/A THR 174.A OG1 GLN 177.A OE1 no hydrogen 3.321 N/A GLN 176.A NE2 GLU 215.A OE1 no hydrogen 3.524 N/A GLN 177.A N THR 174.A OG1 no hydrogen 3.022 N/A ALA 178.A N THR 174.A O no hydrogen 2.882 N/A GLN 179.A N PRO 175.A O no hydrogen 2.863 N/A GLN 179.A NE2 ASP 221.A OD2 no hydrogen 2.778 N/A GLU 180.A N GLN 176.A O no hydrogen 2.963 N/A HIS 182.A N ALA 178.A O no hydrogen 3.107 N/A HIS 182.A ND1 ASP 221.A O no hydrogen 3.006 N/A GLU 183.A N GLN 179.A O no hydrogen 2.835 N/A LYS 184.A N GLU 180.A O no hydrogen 3.031 N/A LYS 184.A NZ GLU 137.A OE2 no hydrogen 2.800 N/A LEU 185.A N VAL 181.A O no hydrogen 2.787 N/A ARG 186.A N HIS 182.A O no hydrogen 2.881 N/A ARG 186.A NE ASP 221.A OD1 no hydrogen 2.761 N/A ARG 186.A NH1 ALA 198.A O no hydrogen 2.791 N/A ARG 186.A NH1 THR 201.A O no hydrogen 2.902 N/A ARG 186.A NH2 ASP 221.A O no hydrogen 3.039 N/A ARG 186.A NH2 ASP 223.A OD2 no hydrogen 2.613 N/A GLY 187.A N GLU 183.A O no hydrogen 3.092 N/A TRP 188.A N LYS 184.A O no hydrogen 2.951 N/A LEU 189.A N LEU 185.A O no hydrogen 3.050 N/A LYS 190.A N ARG 186.A O no hydrogen 2.866 N/A LYS 190.A NZ ASP 195.A OD1 no hydrogen 3.416 N/A SER 191.A N GLY 187.A O no hydrogen 2.872 N/A ASN 192.A N TRP 188.A O no hydrogen 2.868 N/A ASN 192.A ND2 TRP 188.A O no hydrogen 2.895 N/A VAL 193.A N LEU 189.A O no hydrogen 2.850 N/A SER 194.A N LEU 189.A O no hydrogen 3.071 N/A VAL 197.A N SER 194.A OG no hydrogen 2.988 N/A ALA 198.A N SER 194.A O no hydrogen 2.957 N/A GLN 199.A N ASP 195.A O no hydrogen 2.782 N/A SER 200.A N ALA 196.A O no hydrogen 3.141 N/A SER 200.A OG ALA 196.A O no hydrogen 2.675 N/A THR 201.A N VAL 197.A O no hydrogen 3.007 N/A THR 201.A OG1 VAL 197.A O no hydrogen 2.534 N/A ARG 202.A NH1 LYS 2.A O no hydrogen 2.832 N/A ARG 202.A NH1 GLU 35.A OE1 no hydrogen 2.846 N/A ARG 202.A NH2 GLU 35.A OE1 no hydrogen 2.845 N/A ILE 203.A N ASP 223.A OD2 no hydrogen 2.784 N/A ILE 204.A N LEU 159.A O no hydrogen 2.751 N/A TYR 205.A N GLY 224.A O no hydrogen 2.923 N/A GLY 206.A N TYR 161.A O no hydrogen 2.663 N/A THR 210.A N THR 213.A OG1 no hydrogen 3.096 N/A THR 210.A OG1 THR 213.A OG1 no hydrogen 3.222 N/A GLY 211.A N GLU 235.A OE2 no hydrogen 2.754 N/A THR 213.A N THR 210.A O no hydrogen 3.236 N/A THR 213.A N THR 210.A OG1 no hydrogen 3.211 N/A THR 213.A OG1 THR 210.A OG1 no hydrogen 3.222 N/A LEU 216.A N THR 213.A O no hydrogen 3.437 N/A SER 218.A N LYS 214.A O no hydrogen 3.115 N/A SER 218.A OG LYS 214.A O no hydrogen 3.141 N/A SER 218.A OG GLU 215.A O no hydrogen 2.695 N/A GLN 219.A N LEU 216.A O no hydrogen 3.075 N/A ASP 221.A N GLN 179.A OE1 no hydrogen 2.813 N/A VAL 222.A N GLN 219.A O no hydrogen 3.053 N/A ASP 223.A N ILE 203.A O no hydrogen 2.954 N/A PHE 225.A N PHE 4.A O no hydrogen 2.916 N/A LEU 226.A N TYR 205.A O no hydrogen 3.086 N/A VAL 227.A N GLY 6.A O no hydrogen 2.670 N/A SER 231.A N GLY 228.A O no hydrogen 3.002 N/A SER 231.A OG ASN 8.A O no hydrogen 3.169 N/A SER 231.A OG GLY 228.A O no hydrogen 2.649 N/A LEU 232.A N GLY 229.A O no hydrogen 3.166 N/A LYS 233.A N ALA 230.A O no hydrogen 3.209 N/A PHE 236.A N LYS 233.A O no hydrogen 2.980 N/A VAL 237.A N PRO 234.A O no hydrogen 2.806 N/A ILE 239.A N GLU 235.A O no hydrogen 3.235 N/A ILE 240.A N PHE 236.A O no hydrogen 2.889 N/A ASN 241.A N VAL 237.A O no hydrogen 3.036 N/A ALA 242.A N ILE 239.A O no hydrogen 3.219 N/A LYS 243.A NZ ALA 217.A O no hydrogen 3.311 N/A GLN 244.A N ASN 241.A O no hydrogen 3.148 N/A GLN 244.A NE2 ASP 33.A OD1 no hydrogen 2.767 N/A