Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6d8z_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A NH1 SER 152.A OG no hydrogen 3.178 N/A HIS 5.A N LEU 1.A O no hydrogen 3.331 N/A TYR 6.A N LYS 2.A O no hydrogen 3.391 N/A VAL 7.A N ARG 3.A O no hydrogen 3.252 N/A LEU 8.A N ARG 4.A O no hydrogen 3.474 N/A GLN 9.A N HIS 5.A O no hydrogen 2.850 N/A GLU 10.A N TYR 6.A O no hydrogen 3.033 N/A LEU 11.A N VAL 7.A O no hydrogen 3.001 N/A VAL 12.A N LEU 8.A O no hydrogen 3.248 N/A GLU 13.A N GLN 9.A O no hydrogen 3.164 N/A THR 14.A N GLU 10.A O no hydrogen 3.002 N/A THR 14.A OG1 GLU 10.A O no hydrogen 2.709 N/A THR 14.A OG1 LEU 11.A O no hydrogen 3.312 N/A GLU 15.A N VAL 12.A O no hydrogen 2.968 N/A ARG 16.A N VAL 12.A O no hydrogen 3.217 N/A ARG 16.A NE GLU 69.A OE2 no hydrogen 3.502 N/A ASP 17.A N GLU 13.A O no hydrogen 3.448 N/A TYR 18.A N THR 14.A O no hydrogen 2.850 N/A TYR 18.A OH TYR 92.A OH no hydrogen 2.725 N/A VAL 19.A N GLU 15.A O no hydrogen 2.965 N/A ARG 20.A N ARG 16.A O no hydrogen 3.159 N/A ARG 20.A NE ASP 21.A OD1 no hydrogen 3.254 N/A ARG 20.A NH2 ASP 21.A OD1 no hydrogen 2.641 N/A ASP 21.A N ASP 17.A O no hydrogen 2.955 N/A LEU 22.A N TYR 18.A O no hydrogen 3.021 N/A GLY 23.A N VAL 19.A O no hydrogen 2.850 N/A TYR 24.A N ARG 20.A O no hydrogen 2.988 N/A TYR 24.A N ASP 21.A O no hydrogen 3.106 N/A VAL 25.A N LEU 22.A O no hydrogen 3.004 N/A VAL 26.A N LEU 22.A O no hydrogen 2.868 N/A GLU 27.A N GLY 23.A O no hydrogen 2.919 N/A TYR 29.A N TYR 24.A O no hydrogen 3.238 N/A TYR 29.A OH PHE 114.A O no hydrogen 3.424 N/A MET 30.A N VAL 25.A O no hydrogen 2.926 N/A MET 33.A N TYR 29.A O no hydrogen 3.025 N/A LYS 34.A N MET 30.A O no hydrogen 2.963 N/A GLU 35.A N ALA 31.A O no hydrogen 2.895 N/A ASP 36.A N LEU 32.A O no hydrogen 2.799 N/A GLY 37.A N MET 33.A O no hydrogen 3.187 N/A MET 42.A N PRO 39.A O no hydrogen 3.216 N/A LYS 45.A N MET 42.A O no hydrogen 3.019 N/A VAL 49.A N LYS 45.A O no hydrogen 3.397 N/A PHE 50.A N ASP 46.A O no hydrogen 3.305 N/A GLY 51.A N LYS 47.A O no hydrogen 3.212 N/A ASN 52.A ND2 GLN 55.A OE1 no hydrogen 3.115 N/A ASN 52.A ND2 MET 91.A O no hydrogen 3.320 N/A ILE 53.A N PHE 50.A O no hydrogen 3.196 N/A ILE 56.A N ASN 52.A O no hydrogen 3.178 N/A TYR 57.A N ILE 53.A O no hydrogen 2.804 N/A TYR 57.A OH GLU 27.A OE1 no hydrogen 3.236 N/A ASP 58.A N HIS 54.A O no hydrogen 2.936 N/A TRP 59.A N GLN 55.A O no hydrogen 3.281 N/A HIS 60.A N ILE 56.A O no hydrogen 3.113 N/A HIS 60.A ND1 GLU 15.A OE2 no hydrogen 2.846 N/A ARG 61.A N TYR 57.A O no hydrogen 2.884 N/A ARG 61.A NH1 ASP 62.A OD1 no hydrogen 2.962 N/A ASP 62.A N ASP 58.A O no hydrogen 2.839 N/A PHE 63.A N TRP 59.A O no hydrogen 3.142 N/A PHE 64.A N TRP 59.A O no hydrogen 2.896 N/A LEU 65.A N HIS 60.A O no hydrogen 3.051 N/A GLU 67.A N PHE 63.A O no hydrogen 3.228 N/A LEU 68.A N PHE 64.A O no hydrogen 3.037 N/A GLU 69.A N LEU 65.A O no hydrogen 2.942 N/A LYS 70.A N GLY 66.A O no hydrogen 3.267 N/A LYS 70.A NZ GLU 67.A OE2 no hydrogen 3.350 N/A CYS 71.A N LEU 68.A O no hydrogen 3.245 N/A CYS 71.A SG GLU 67.A O no hydrogen 3.700 N/A LYS 77.A N ASP 74.A O no hydrogen 3.357 N/A LEU 78.A N PRO 75.A O no hydrogen 3.332 N/A LEU 81.A N LYS 77.A O no hydrogen 2.963 N/A LYS 84.A N SER 80.A O no hydrogen 2.958 N/A HIS 85.A N LEU 81.A O no hydrogen 3.233 N/A GLU 86.A N VAL 83.A O no hydrogen 3.373 N/A LEU 89.A N HIS 85.A O no hydrogen 3.288 N/A LEU 89.A N GLU 86.A O no hydrogen 3.152 N/A HIS 90.A N ARG 87.A O no hydrogen 3.126 N/A HIS 90.A ND1 GLU 86.A O no hydrogen 3.051 N/A TYR 92.A OH TYR 18.A OH no hydrogen 2.725 N/A TYR 92.A OH HIS 60.A NE2 no hydrogen 2.663 N/A ILE 93.A N HIS 90.A O no hydrogen 3.112 N/A TYR 95.A N MET 91.A O no hydrogen 2.987 N/A TYR 95.A OH LEU 131.A O no hydrogen 2.639 N/A CYS 96.A N TYR 92.A O no hydrogen 2.843 N/A CYS 96.A SG TYR 92.A O no hydrogen 3.233 N/A GLN 97.A N ILE 93.A O no hydrogen 2.893 N/A ASN 98.A N ALA 94.A O no hydrogen 3.250 N/A ASN 98.A N TYR 95.A O no hydrogen 3.249 N/A ASN 98.A ND2 ILE 48.A O no hydrogen 2.732 N/A LYS 99.A N TYR 95.A O no hydrogen 2.987 N/A LYS 99.A NZ GLU 103.A OE2 no hydrogen 2.809 N/A SER 102.A N ASN 98.A O no hydrogen 3.082 N/A SER 102.A OG VAL 49.A O no hydrogen 2.449 N/A GLU 103.A N LYS 99.A O no hydrogen 2.926 N/A HIS 104.A N PRO 100.A O no hydrogen 3.359 N/A VAL 106.A N SER 102.A O no hydrogen 3.252 N/A SER 107.A N GLU 103.A O no hydrogen 3.109 N/A SER 107.A OG GLU 103.A O no hydrogen 3.524 N/A SER 107.A OG HIS 104.A O no hydrogen 2.984 N/A GLU 108.A N ILE 105.A O no hydrogen 3.089 N/A TYR 109.A N VAL 106.A O no hydrogen 3.051 N/A THR 112.A N TYR 109.A O no hydrogen 3.196 N/A THR 112.A OG1 TYR 109.A O no hydrogen 3.372 N/A PHE 114.A N TYR 109.A O no hydrogen 3.088 N/A ASP 116.A N THR 112.A O no hydrogen 3.149 N/A LEU 117.A N PHE 113.A O no hydrogen 3.205 N/A LYS 118.A N PHE 114.A O no hydrogen 2.875 N/A LYS 118.A NZ HIS 123.A O no hydrogen 3.072 N/A GLN 119.A N GLU 115.A O no hydrogen 2.926 N/A ARG 120.A N ASP 116.A O no hydrogen 3.096 N/A ARG 120.A NH1 ASP 36.A OD2 no hydrogen 3.038 N/A LEU 121.A N LEU 117.A O no hydrogen 2.925 N/A GLY 122.A N LYS 118.A O no hydrogen 2.860 N/A LEU 130.A N GLN 126.A O no hydrogen 3.137 N/A LEU 131.A N LEU 127.A O no hydrogen 2.842 N/A LYS 133.A N LEU 130.A O no hydrogen 3.321 N/A LYS 133.A NZ ASP 21.A OD2 no hydrogen 3.140 N/A GLN 136.A N ILE 132.A O no hydrogen 2.985 N/A ARG 137.A N LYS 133.A O no hydrogen 2.948 N/A ARG 137.A NE GLU 15.A OE1 no hydrogen 3.167 N/A ARG 137.A NH1 THR 14.A OG1 no hydrogen 2.815 N/A ARG 137.A NH2 LEU 11.A O no hydrogen 2.817 N/A ARG 137.A NH2 GLU 15.A OE1 no hydrogen 2.906 N/A ILE 138.A N PRO 134.A O no hydrogen 3.379 N/A LYS 140.A N GLN 136.A O no hydrogen 2.863 N/A TYR 141.A N ARG 137.A O no hydrogen 2.957 N/A TYR 141.A OH GLU 15.A OE1 no hydrogen 2.652 N/A LEU 143.A N MET 139.A O no hydrogen 3.012 N/A LEU 144.A N LYS 140.A O no hydrogen 3.054 N/A LEU 145.A N TYR 141.A O no hydrogen 3.001 N/A LYS 146.A N GLN 142.A O no hydrogen 3.227 N/A ASP 147.A N LEU 143.A O no hydrogen 3.427 N/A PHE 148.A N LEU 144.A O no hydrogen 2.777 N/A LEU 149.A N LEU 145.A O no hydrogen 2.826 N/A LYS 150.A N LYS 146.A O no hydrogen 2.947 N/A TYR 151.A N ASP 147.A O no hydrogen 3.123 N/A SER 152.A N PHE 148.A O no hydrogen 3.211 N/A SER 152.A OG PHE 148.A O no hydrogen 2.702 N/A LYS 153.A N LEU 149.A O no hydrogen 2.944 N/A LYS 154.A N LYS 150.A O no hydrogen 3.319 N/A ALA 155.A N TYR 151.A O no hydrogen 3.186 N/A LEU 157.A N SER 152.A O no hydrogen 3.397 N/A THR 159.A OG1 GLU 163.A OE2 no hydrogen 3.015 N/A GLU 163.A N THR 159.A O no hydrogen 2.810 N/A ARG 164.A N SER 160.A O no hydrogen 3.472 N/A ALA 165.A N GLU 161.A O no hydrogen 3.328 N/A VAL 166.A N LEU 162.A O no hydrogen 3.128 N/A GLU 167.A N GLU 163.A O no hydrogen 3.130 N/A VAL 168.A N ARG 164.A O no hydrogen 3.169 N/A MET 169.A N ALA 165.A O no hydrogen 3.073 N/A CYS 170.A N GLU 167.A O no hydrogen 3.185 N/A CYS 170.A SG VAL 166.A O no hydrogen 3.406 N/A ILE 171.A N GLU 167.A O no hydrogen 3.264 N/A VAL 172.A N VAL 168.A O no hydrogen 3.268 N/A ARG 174.A N CYS 170.A O no hydrogen 3.140 N/A ARG 175.A N ILE 171.A O no hydrogen 3.035 N/A ARG 175.A NH1 LEU 198.A O no hydrogen 3.419 N/A ARG 175.A NH2 LEU 198.A O no hydrogen 2.809 N/A CYS 176.A N VAL 172.A O no hydrogen 2.951 N/A CYS 176.A SG VAL 172.A O no hydrogen 3.229 N/A ASN 177.A N PRO 173.A O no hydrogen 3.084 N/A ASP 178.A N ARG 174.A O no hydrogen 2.909 N/A MET 179.A N ARG 175.A O no hydrogen 2.798 N/A MET 180.A N CYS 176.A O no hydrogen 3.044 N/A ASN 181.A N ASN 177.A O no hydrogen 2.961 N/A ASN 181.A ND2 GLN 201.A OE1 no hydrogen 3.112 N/A VAL 182.A N ASP 178.A O no hydrogen 3.274 N/A GLY 183.A N MET 179.A O no hydrogen 3.371 N/A ARG 184.A N ASN 181.A O no hydrogen 2.849 N/A ARG 184.A NH1 GLU 103.A OE1 no hydrogen 2.642 N/A ARG 184.A NH2 GLU 103.A OE1 no hydrogen 3.252 N/A ARG 184.A NH2 GLU 103.A OE2 no hydrogen 3.206 N/A LEU 185.A N VAL 182.A O no hydrogen 3.236 N/A GLN 186.A N PHE 239.A O no hydrogen 2.834 N/A ALA 194.A N LYS 191.A O no hydrogen 3.149 N/A GLN 195.A N ILE 192.A O no hydrogen 3.316 N/A GLN 195.A NE2 LYS 191.A O no hydrogen 3.145 N/A LYS 197.A N GLU 219.A OE1 no hydrogen 2.976 N/A LEU 199.A N LEU 217.A O no hydrogen 2.703 N/A LEU 200.A N LEU 217.A O no hydrogen 3.359 N/A GLN 201.A NE2 ASP 178.A O no hydrogen 2.920 N/A ASP 202.A N ILE 215.A O no hydrogen 3.239 N/A PHE 204.A N ARG 213.A O no hydrogen 2.889 N/A LEU 205.A N HIS 279.A O no hydrogen 3.257 N/A VAL 206.A N ARG 211.A O no hydrogen 2.824 N/A THR 207.A N ILE 277.A O no hydrogen 3.244 N/A ARG 211.A N VAL 206.A O no hydrogen 3.144 N/A ARG 213.A N PHE 204.A O no hydrogen 2.874 N/A ARG 213.A NH1 GLU 212.A O no hydrogen 2.960 N/A ARG 214.A N SER 225.A O no hydrogen 2.694 N/A ARG 214.A NE GLN 201.A OE1 no hydrogen 3.077 N/A ARG 214.A NH1 THR 203.A OG1 no hydrogen 2.741 N/A ARG 214.A NH2 GLN 201.A OE1 no hydrogen 2.629 N/A ILE 215.A N ASP 202.A O no hydrogen 2.771 N/A PHE 216.A N ILE 223.A O no hydrogen 2.846 N/A LEU 217.A N LEU 200.A O no hydrogen 2.822 N/A PHE 218.A N ILE 221.A O no hydrogen 2.881 N/A GLU 219.A N LYS 197.A O no hydrogen 3.049 N/A GLN 220.A N GLN 195.A O no hydrogen 3.166 N/A VAL 222.A N ILE 245.A O no hydrogen 2.784 N/A ILE 223.A N PHE 216.A O no hydrogen 2.930 N/A PHE 224.A N ASN 243.A O no hydrogen 2.845 N/A SER 225.A N ARG 214.A O no hydrogen 2.858 N/A SER 225.A OG ARG 214.A O no hydrogen 2.756 N/A GLU 226.A N LEU 240.A O no hydrogen 2.749 N/A LEU 228.A N GLY 238.A O no hydrogen 2.965 N/A SER 235.A N GLU 103.A OE1 no hydrogen 3.271 N/A SER 235.A OG GLU 103.A OE2 no hydrogen 2.668 N/A PHE 239.A N ARG 184.A O no hydrogen 3.079 N/A LEU 240.A N GLU 226.A O no hydrogen 2.808 N/A PHE 241.A N GLN 186.A O no hydrogen 2.951 N/A LYS 242.A N PHE 224.A O no hydrogen 3.012 N/A LYS 242.A NZ GLU 226.A OE2 no hydrogen 3.478 N/A ILE 245.A N VAL 222.A O no hydrogen 2.843 N/A VAL 247.A N GLN 220.A O no hydrogen 3.200 N/A CYS 249.A N LYS 246.A O no hydrogen 2.902 N/A LEU 250.A N VAL 247.A O no hydrogen 3.100 N/A CYS 251.A N THR 266.A O no hydrogen 3.110 N/A GLU 253.A N ALA 264.A O no hydrogen 3.162 N/A ASN 255.A N GLU 253.A OE2 no hydrogen 3.407 N/A ASP 259.A N VAL 256.A O no hydrogen 3.281 N/A CYS 261.A N ASP 259.A OD1 no hydrogen 2.810 N/A LYS 262.A N ASP 259.A O no hydrogen 3.366 N/A PHE 263.A N LEU 278.A O no hydrogen 3.251 N/A ALA 264.A N GLU 253.A O no hydrogen 2.878 N/A LEU 265.A N PHE 276.A O no hydrogen 2.860 N/A THR 266.A N CYS 251.A O no hydrogen 3.005 N/A SER 267.A N GLU 274.A O no hydrogen 2.762 N/A ARG 268.A N CYS 249.A O no hydrogen 3.267 N/A VAL 272.A N THR 269.A O no hydrogen 2.916 N/A GLU 274.A N SER 267.A O no hydrogen 3.026 N/A PHE 276.A N LEU 265.A O no hydrogen 2.752 N/A ILE 277.A N THR 207.A O no hydrogen 3.098 N/A LEU 278.A N PHE 263.A O no hydrogen 2.780 N/A HIS 279.A N LEU 205.A O no hydrogen 2.885 N/A SER 280.A N CYS 261.A O no hydrogen 2.656 N/A ARG 286.A NE LYS 262.A O no hydrogen 3.101 N/A ARG 286.A NH2 GLU 254.A O no hydrogen 2.921 N/A GLN 287.A N PRO 283.A O no hydrogen 3.163 N/A THR 288.A N SER 284.A O no hydrogen 3.110 N/A THR 288.A OG1 SER 284.A O no hydrogen 2.665 N/A TRP 289.A N VAL 285.A O no hydrogen 3.108 N/A TRP 289.A NE1 ASP 202.A OD2 no hydrogen 3.085 N/A ILE 290.A N ARG 286.A O no hydrogen 2.972 N/A HIS 291.A N GLN 287.A O no hydrogen 3.352 N/A GLU 292.A N THR 288.A O no hydrogen 3.196 N/A ILE 293.A N TRP 289.A O no hydrogen 2.838 N/A ASN 294.A N ILE 290.A O no hydrogen 2.977 N/A ASN 294.A ND2 GLU 254.A OE2 no hydrogen 2.991 N/A GLN 295.A N HIS 291.A O no hydrogen 3.115 N/A ILE 296.A N GLU 292.A O no hydrogen 3.300 N/A LEU 297.A N ILE 293.A O no hydrogen 3.000 N/A GLU 298.A N ASN 294.A O no hydrogen 3.352 N/A ASN 299.A N ILE 296.A O no hydrogen 3.430 N/A