Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6e9w_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 8.A N GLU 4.A O no hydrogen 3.328 N/A LEU 9.A N LYS 5.A O no hydrogen 3.131 N/A LEU 10.A N ASP 7.A O no hydrogen 3.031 N/A ARG 11.A N ASN 8.A O no hydrogen 3.007 N/A ASP 12.A N ASN 8.A O no hydrogen 2.801 N/A LYS 14.A N ASP 12.A OD1 no hydrogen 3.189 N/A SER 15.A N ASP 12.A O no hydrogen 2.990 N/A SER 15.A OG LEU 9.A O no hydrogen 2.652 N/A VAL 17.A N SER 15.A OG no hydrogen 3.108 N/A ASN 18.A ND2 ASP 12.A O no hydrogen 3.144 N/A SER 19.A N LEU 10.A O no hydrogen 3.084 N/A SER 19.A OG LEU 10.A O no hydrogen 3.052 N/A ASP 20.A N ASN 381.A OD1 no hydrogen 2.906 N/A CYS 21.A N ASN 18.A OD1 no hydrogen 2.960 N/A CYS 21.A SG GLU 16.A O no hydrogen 3.234 N/A LEU 22.A N ASN 18.A O no hydrogen 2.846 N/A LEU 23.A N SER 19.A O no hydrogen 2.791 N/A ASP 24.A N ASP 20.A O no hydrogen 2.901 N/A GLY 25.A N CYS 21.A O no hydrogen 2.969 N/A LEU 26.A N LEU 22.A O no hydrogen 3.264 N/A ASP 27.A N LEU 23.A O no hydrogen 3.136 N/A ALA 28.A N ASP 24.A O no hydrogen 2.821 N/A LEU 29.A N GLY 25.A O no hydrogen 2.995 N/A VAL 30.A N LEU 26.A O no hydrogen 2.867 N/A TYR 31.A N ASP 27.A O no hydrogen 3.052 N/A ASP 32.A N ALA 28.A O no hydrogen 2.816 N/A ASP 34.A N VAL 30.A O no hydrogen 3.452 N/A PHE 35.A N LEU 33.A O no hydrogen 2.731 N/A LEU 38.A N PHE 35.A O no hydrogen 2.825 N/A ARG 39.A N PHE 35.A O no hydrogen 2.935 N/A ARG 39.A NE ASP 34.A OD1 no hydrogen 3.496 N/A ARG 39.A NH2 ASP 45.A OD1 no hydrogen 3.377 N/A ARG 39.A NH2 SER 49.A OG no hydrogen 2.872 N/A ASN 41.A N LEU 38.A O no hydrogen 2.947 N/A ASN 43.A N ASN 41.A OD1 no hydrogen 2.801 N/A ASP 45.A N ASN 41.A O no hydrogen 2.835 N/A ASN 46.A N LYS 42.A O no hydrogen 3.099 N/A LEU 48.A N ILE 44.A O no hydrogen 3.246 N/A SER 49.A N ASP 45.A O no hydrogen 2.959 N/A SER 49.A OG ASP 45.A O no hydrogen 3.196 N/A ARG 50.A N ASN 46.A O no hydrogen 2.793 N/A TYR 51.A N PHE 47.A O no hydrogen 2.795 N/A ILE 55.A N TYR 51.A O no hydrogen 2.990 N/A ASN 56.A N LYS 52.A O no hydrogen 3.269 N/A LYS 57.A N ASP 53.A O no hydrogen 3.077 N/A ILE 58.A N THR 54.A O no hydrogen 2.929 N/A ARG 59.A N ILE 55.A O no hydrogen 2.842 N/A ARG 59.A NH2 ASP 27.A O no hydrogen 3.397 N/A ARG 59.A NH2 ASP 27.A OD1 no hydrogen 2.773 N/A ASP 60.A N ASN 56.A O no hydrogen 3.257 N/A LEU 61.A N LYS 57.A O no hydrogen 2.864 N/A ARG 62.A N ILE 58.A O no hydrogen 2.734 N/A ARG 62.A NH2 ASP 24.A OD1 no hydrogen 2.987 N/A LYS 64.A N ASP 67.A OD2 no hydrogen 2.820 N/A LYS 64.A NZ ASP 67.A OD1 no hydrogen 2.898 N/A ASP 67.A N LYS 64.A O no hydrogen 3.105 N/A TYR 68.A N ALA 65.A O no hydrogen 2.828 N/A GLU 69.A N ARG 86.A O no hydrogen 2.783 N/A VAL 71.A N LEU 84.A O no hydrogen 2.773 N/A LYS 72.A N LEU 84.A O no hydrogen 3.429 N/A LYS 72.A NZ ASP 357.A OD1 no hydrogen 2.983 N/A ILE 74.A N VAL 82.A O no hydrogen 2.907 N/A GLY 77.A N GLY 80.A O no hydrogen 2.879 N/A GLY 80.A N GLY 77.A O no hydrogen 3.156 N/A VAL 82.A N GLY 75.A O no hydrogen 3.006 N/A GLN 83.A N MET 96.A O no hydrogen 2.837 N/A LEU 84.A N LYS 72.A O no hydrogen 2.748 N/A VAL 85.A N TYR 94.A O no hydrogen 2.894 N/A ARG 86.A N GLU 69.A O no hydrogen 2.881 N/A ARG 86.A NH1 ARG 91.A O no hydrogen 3.182 N/A ARG 86.A NH1 ASP 349.A OD2 no hydrogen 2.913 N/A HIS 87.A N LYS 92.A O no hydrogen 2.897 N/A LYS 88.A N ASP 67.A O no hydrogen 3.050 N/A LYS 88.A NZ GLU 66.A O no hydrogen 3.020 N/A THR 90.A N HIS 87.A ND1 no hydrogen 3.008 N/A ARG 91.A N HIS 87.A O no hydrogen 2.679 N/A TYR 94.A N VAL 85.A O no hydrogen 3.053 N/A ALA 95.A N MET 145.A O no hydrogen 3.167 N/A MET 96.A N GLN 83.A O no hydrogen 2.868 N/A LYS 97.A N MET 143.A O no hydrogen 2.805 N/A LYS 97.A NZ GLU 116.A OE1 no hydrogen 2.804 N/A LYS 97.A NZ GLU 116.A OE2 no hydrogen 3.280 N/A LEU 98.A N GLU 81.A O no hydrogen 2.820 N/A LEU 99.A N LEU 141.A O no hydrogen 3.235 N/A SER 100.A N PHE 79.A O no hydrogen 2.984 N/A SER 100.A OG GLU 103.A OE2 no hydrogen 3.132 N/A LYS 101.A N ARG 139.A O no hydrogen 3.026 N/A LYS 101.A NZ GLN 136.A OE1 no hydrogen 3.214 N/A LYS 101.A NZ ASP 137.A O no hydrogen 2.704 N/A GLU 103.A N SER 100.A OG no hydrogen 3.097 N/A MET 104.A N SER 100.A O no hydrogen 3.060 N/A ILE 105.A N LYS 101.A O no hydrogen 2.877 N/A LYS 106.A N PHE 102.A O no hydrogen 2.815 N/A ARG 107.A N GLU 103.A O no hydrogen 2.710 N/A ARG 107.A NH1 GLU 103.A OE1 no hydrogen 2.984 N/A SER 108.A N MET 104.A O no hydrogen 3.017 N/A SER 108.A OG SER 110.A O no hydrogen 2.830 N/A TRP 114.A N ALA 111.A O no hydrogen 3.451 N/A GLU 116.A N PHE 112.A O no hydrogen 3.425 N/A ARG 117.A N PHE 113.A O no hydrogen 2.989 N/A ASP 118.A N TRP 114.A O no hydrogen 3.083 N/A ILE 119.A N GLU 115.A O no hydrogen 2.798 N/A MET 120.A N GLU 116.A O no hydrogen 3.232 N/A PHE 122.A N ASP 118.A O no hydrogen 3.129 N/A ALA 123.A N ILE 119.A O no hydrogen 3.033 N/A TRP 127.A N SER 125.A OG no hydrogen 3.247 N/A VAL 129.A N LEU 206.A O no hydrogen 3.171 N/A GLN 130.A N GLU 146.A OE1 no hydrogen 2.985 N/A LEU 131.A N MET 120.A O no hydrogen 2.727 N/A PHE 132.A N VAL 144.A O no hydrogen 2.789 N/A ALA 134.A N TYR 378.A O no hydrogen 3.186 N/A PHE 135.A N TYR 142.A O no hydrogen 3.122 N/A GLN 136.A NE2 PHE 373.A O no hydrogen 3.063 N/A ASP 137.A N TYR 140.A O no hydrogen 2.980 N/A ARG 139.A N ASP 137.A OD1 no hydrogen 2.840 N/A TYR 140.A N ASP 137.A OD1 no hydrogen 2.806 N/A LEU 141.A N LEU 99.A O no hydrogen 2.897 N/A TYR 142.A N PHE 135.A O no hydrogen 2.844 N/A TYR 142.A OH ASP 137.A OD2 no hydrogen 3.018 N/A MET 143.A N LYS 97.A O no hydrogen 2.914 N/A VAL 144.A N TYR 133.A O no hydrogen 2.920 N/A MET 145.A N ALA 95.A O no hydrogen 2.892 N/A GLU 146.A N GLN 130.A O no hydrogen 3.107 N/A TYR 147.A OH ASP 351.A O no hydrogen 2.884 N/A GLY 150.A N LEU 198.A O no hydrogen 2.917 N/A GLY 151.A N MET 148.A O no hydrogen 3.350 N/A LEU 153.A N PRO 193.A O no hydrogen 3.291 N/A LEU 153.A N MET 196.A O no hydrogen 3.017 N/A ASN 155.A N ASP 152.A OD1 no hydrogen 3.372 N/A LEU 156.A N ASP 152.A O no hydrogen 3.400 N/A MET 157.A N LEU 153.A O no hydrogen 2.964 N/A SER 158.A N VAL 154.A O no hydrogen 3.234 N/A SER 158.A N ASN 155.A O no hydrogen 3.189 N/A SER 158.A OG ASN 155.A O no hydrogen 3.075 N/A SER 158.A OG ASN 159.A OD1 no hydrogen 3.440 N/A ASN 159.A N ASN 155.A O no hydrogen 3.043 N/A TYR 160.A N LEU 156.A O no hydrogen 3.154 N/A ALA 167.A N PRO 163.A O no hydrogen 2.910 N/A ARG 168.A N GLU 164.A O no hydrogen 2.792 N/A ARG 168.A NE PHE 324.A O no hydrogen 2.879 N/A PHE 169.A N LYS 165.A O no hydrogen 3.269 N/A PHE 169.A N TRP 166.A O no hydrogen 3.005 N/A TYR 170.A N TRP 166.A O no hydrogen 3.164 N/A THR 171.A N ALA 167.A O no hydrogen 2.892 N/A THR 171.A OG1 ALA 167.A O no hydrogen 2.698 N/A ALA 172.A N ARG 168.A O no hydrogen 3.116 N/A GLU 173.A N PHE 169.A O no hydrogen 2.907 N/A VAL 174.A N TYR 170.A O no hydrogen 3.069 N/A VAL 175.A N THR 171.A O no hydrogen 2.901 N/A LEU 176.A N ALA 172.A O no hydrogen 3.096 N/A ALA 177.A N GLU 173.A O no hydrogen 2.877 N/A LEU 178.A N VAL 174.A O no hydrogen 2.794 N/A ASP 179.A N VAL 175.A O no hydrogen 2.883 N/A ALA 180.A N LEU 176.A O no hydrogen 2.810 N/A ILE 181.A N ALA 177.A O no hydrogen 3.157 N/A HIS 182.A N LEU 178.A O no hydrogen 2.853 N/A HIS 182.A NE2 ASP 247.A OD2 no hydrogen 2.832 N/A SER 183.A N ASP 179.A O no hydrogen 2.845 N/A MET 184.A N ALA 180.A O no hydrogen 3.102 N/A GLY 185.A N HIS 182.A O no hydrogen 2.814 N/A PHE 186.A N ILE 181.A O no hydrogen 3.149 N/A ILE 187.A N MET 213.A O no hydrogen 3.053 N/A HIS 188.A N ASP 247.A OD2 no hydrogen 2.773 N/A ARG 189.A N ASP 247.A OD1 no hydrogen 2.743 N/A ARG 189.A NE TYR 242.A OH no hydrogen 3.014 N/A ARG 189.A NH1 TYR 242.A OH no hydrogen 3.500 N/A ARG 189.A NH2 THR 211.A O no hydrogen 2.699 N/A LYS 192.A NZ THR 229.A OG1 no hydrogen 2.775 N/A ASN 195.A N LYS 192.A O no hydrogen 2.797 N/A ASN 195.A ND2 ASP 190.A O no hydrogen 2.765 N/A ASN 195.A ND2 ASP 190.A OD2 no hydrogen 3.341 N/A MET 196.A N PRO 193.A O no hydrogen 3.313 N/A LEU 197.A N LYS 205.A O no hydrogen 3.000 N/A LEU 198.A N GLY 151.A O no hydrogen 2.817 N/A ASP 199.A N HIS 203.A O no hydrogen 3.066 N/A SER 201.A OG ASP 199.A OD1 no hydrogen 3.021 N/A GLY 202.A N ASP 199.A O no hydrogen 2.971 N/A HIS 203.A N ASP 199.A OD1 no hydrogen 3.071 N/A HIS 203.A ND1 GLU 173.A OE2 no hydrogen 2.685 N/A HIS 203.A NE2 THR 338.A O no hydrogen 2.919 N/A LEU 204.A N GLU 173.A OE1 no hydrogen 2.878 N/A LYS 205.A N LEU 197.A O no hydrogen 3.106 N/A LEU 206.A N TRP 127.A O no hydrogen 2.828 N/A ALA 207.A N ASN 195.A O no hydrogen 3.055 N/A GLY 210.A N ASP 208.A OD1 no hydrogen 3.035 N/A THR 211.A OG1 HIS 188.A O no hydrogen 2.808 N/A CYS 212.A N PHE 209.A O no hydrogen 3.098 N/A CYS 212.A SG ILE 187.A O no hydrogen 3.965 N/A MET 213.A N ILE 187.A O no hydrogen 3.294 N/A MET 215.A N GLY 185.A O no hydrogen 2.761 N/A ASN 216.A N MET 220.A O no hydrogen 2.955 N/A ASN 216.A ND2 TYR 241.A OH no hydrogen 3.520 N/A GLU 218.A N ASN 216.A OD1 no hydrogen 2.816 N/A GLY 219.A N ASN 216.A O no hydrogen 2.768 N/A VAL 221.A N TYR 242.A O no hydrogen 2.898 N/A CYS 223.A SG ARG 222.A O no hydrogen 3.356 N/A CYS 223.A SG TYR 242.A OH no hydrogen 3.885 N/A THR 225.A N ASP 224.A OD1 no hydrogen 3.072 N/A THR 229.A OG1 ASP 190.A OD1 no hydrogen 2.781 N/A TYR 232.A OH GLU 257.A OE2 no hydrogen 2.585 N/A SER 234.A OG GLU 236.A OE1 no hydrogen 3.365 N/A LEU 238.A N SER 234.A O no hydrogen 3.223 N/A LYS 239.A N PRO 235.A O no hydrogen 3.120 N/A SER 240.A N GLU 236.A O no hydrogen 3.295 N/A SER 240.A OG VAL 237.A O no hydrogen 3.081 N/A TYR 241.A OH GLU 218.A OE1 no hydrogen 2.804 N/A TYR 242.A N VAL 221.A O no hydrogen 3.213 N/A CYS 246.A SG GLY 243.A O no hydrogen 3.417 N/A CYS 246.A SG ASP 247.A OD1 no hydrogen 3.905 N/A ASP 247.A N ARG 244.A O no hydrogen 2.934 N/A TRP 248.A N GLU 245.A O no hydrogen 3.148 N/A TRP 249.A N CYS 246.A O no hydrogen 3.209 N/A SER 250.A OG TYR 232.A O no hydrogen 2.849 N/A VAL 251.A N TRP 248.A O no hydrogen 3.243 N/A GLY 252.A N TRP 248.A O no hydrogen 3.257 N/A VAL 253.A N TRP 249.A O no hydrogen 3.101 N/A PHE 254.A N SER 250.A O no hydrogen 2.887 N/A LEU 255.A N VAL 251.A O no hydrogen 2.753 N/A TYR 256.A N GLY 252.A O no hydrogen 2.857 N/A TYR 256.A OH THR 285.A O no hydrogen 2.671 N/A GLU 257.A N VAL 253.A O no hydrogen 2.952 N/A MET 258.A N PHE 254.A O no hydrogen 3.367 N/A MET 258.A N LEU 255.A O no hydrogen 3.043 N/A LEU 259.A N LEU 255.A O no hydrogen 3.168 N/A VAL 260.A N TYR 256.A O no hydrogen 2.951 N/A GLY 261.A N GLU 257.A O no hydrogen 3.044 N/A THR 263.A OG1 ASP 231.A OD2 no hydrogen 3.496 N/A SER 269.A OG ASP 268.A OD1 no hydrogen 3.442 N/A THR 273.A OG1 PHE 265.A O no hydrogen 3.230 N/A LYS 276.A N GLY 272.A O no hydrogen 3.085 N/A LYS 276.A NZ TYR 266.A O no hydrogen 3.277 N/A ILE 277.A N THR 273.A O no hydrogen 2.825 N/A MET 278.A N TYR 274.A O no hydrogen 3.075 N/A ASN 279.A N SER 275.A O no hydrogen 3.075 N/A ASN 279.A ND2 ASN 282.A OD1 no hydrogen 3.207 N/A HIS 280.A N ILE 277.A O no hydrogen 3.087 N/A HIS 280.A NE2 ASP 306.A OD1 no hydrogen 3.262 N/A ASN 282.A N ASN 279.A O no hydrogen 2.769 N/A SER 283.A N HIS 280.A O no hydrogen 3.343 N/A SER 283.A OG LYS 276.A O no hydrogen 2.673 N/A SER 283.A OG ASN 279.A O no hydrogen 3.007 N/A LEU 284.A N HIS 280.A O no hydrogen 3.002 N/A THR 285.A OG1 SER 283.A O no hydrogen 3.433 N/A SER 293.A N GLU 164.A OE1 no hydrogen 2.835 N/A SER 293.A OG GLU 164.A OE1 no hydrogen 3.411 N/A SER 293.A OG GLU 164.A OE2 no hydrogen 2.944 N/A SER 293.A OG GLU 295.A OE2 no hydrogen 3.246 N/A ALA 296.A N SER 293.A OG no hydrogen 2.982 N/A LYS 297.A N SER 293.A O no hydrogen 3.327 N/A LYS 297.A NZ ILE 292.A O no hydrogen 2.758 N/A ASN 298.A N LYS 294.A O no hydrogen 3.171 N/A LEU 299.A N GLU 295.A O no hydrogen 3.378 N/A ILE 300.A N ALA 296.A O no hydrogen 3.166 N/A CYS 301.A N LYS 297.A O no hydrogen 2.944 N/A CYS 301.A SG LYS 297.A O no hydrogen 3.167 N/A ALA 302.A N ASN 298.A O no hydrogen 2.794 N/A PHE 303.A N LEU 299.A O no hydrogen 3.241 N/A PHE 303.A N ILE 300.A O no hydrogen 3.106 N/A LEU 304.A N ILE 300.A O no hydrogen 2.834 N/A ARG 307.A NH2 TYR 241.A O no hydrogen 3.466 N/A VAL 309.A N ASP 306.A O no hydrogen 2.961 N/A ARG 310.A N ASP 306.A O no hydrogen 2.859 N/A ARG 310.A NE GLU 245.A O no hydrogen 3.064 N/A ARG 310.A NH1 GLU 236.A OE2 no hydrogen 2.796 N/A ARG 310.A NH1 THR 305.A O no hydrogen 3.123 N/A ARG 310.A NH2 GLU 236.A OE1 no hydrogen 2.812 N/A ARG 310.A NH2 GLU 236.A OE2 no hydrogen 2.816 N/A LEU 311.A N ALA 302.A O no hydrogen 2.803 N/A GLY 312.A N GLU 318.A OE1 no hydrogen 3.090 N/A ARG 313.A N ARG 310.A O no hydrogen 3.326 N/A ASN 314.A N GLU 318.A OE1 no hydrogen 3.365 N/A ILE 319.A N VAL 316.A O no hydrogen 2.935 N/A LYS 320.A N VAL 316.A O no hydrogen 3.078 N/A ARG 321.A N GLU 317.A O no hydrogen 2.783 N/A HIS 322.A N ILE 319.A O no hydrogen 3.228 N/A PHE 324.A N HIS 322.A ND1 no hydrogen 3.046 N/A PHE 325.A N HIS 322.A O no hydrogen 2.990 N/A LYS 326.A N LEU 323.A O no hydrogen 2.894 N/A ASN 327.A ND2 PHE 325.A O no hydrogen 2.905 N/A ASN 327.A ND2 TRP 330.A O no hydrogen 3.269 N/A GLN 329.A N ASN 327.A OD1 no hydrogen 2.939 N/A TRP 330.A N ASN 327.A OD1 no hydrogen 2.929 N/A THR 334.A N ALA 331.A O no hydrogen 2.814 N/A ARG 336.A NH2 ASP 199.A OD2 no hydrogen 2.801 N/A ARG 336.A NH2 LEU 204.A O no hydrogen 3.355 N/A ASP 337.A N THR 334.A O no hydrogen 2.904 N/A THR 338.A N THR 334.A O no hydrogen 3.254 N/A THR 338.A N LEU 335.A O no hydrogen 3.174 N/A THR 338.A OG1 LEU 335.A O no hydrogen 2.989 N/A SER 347.A N ASP 351.A OD2 no hydrogen 2.945 N/A SER 347.A OG ASP 351.A OD2 no hydrogen 2.930 N/A ASP 351.A N SER 348.A O no hydrogen 3.174 N/A SER 353.A N ASP 351.A OD1 no hydrogen 3.371 N/A SER 353.A OG ASP 351.A OD1 no hydrogen 2.676 N/A SER 353.A OG ASP 351.A OD2 no hydrogen 3.531 N/A ASN 354.A ND2 PRO 149.A O no hydrogen 2.840 N/A PHE 355.A N THR 352.A O no hydrogen 3.108 N/A GLN 370.A N ASP 32.A OD2 no hydrogen 2.987 N/A GLN 370.A NE2 ASP 138.A O no hydrogen 2.748 N/A LEU 371.A N GLY 368.A O no hydrogen 3.407 N/A PHE 373.A N GLN 370.A O no hydrogen 3.396 N/A GLY 375.A N ASP 24.A OD2 no hydrogen 3.221 N/A PHE 376.A N PHE 373.A O no hydrogen 3.134 N/A THR 377.A N ASP 24.A OD2 no hydrogen 3.147 N/A THR 377.A OG1 ASP 24.A OD1 no hydrogen 2.765 N/A THR 377.A OG1 ASP 24.A OD2 no hydrogen 3.369 N/A TYR 378.A N ALA 134.A O no hydrogen 2.935 N/A TYR 379.A N ASP 20.A OD1 no hydrogen 3.358 N/A TYR 379.A N ASP 20.A OD2 no hydrogen 3.098 N/A SER 380.A N ASP 20.A OD1 no hydrogen 2.776 N/A SER 380.A OG ASP 20.A OD1 no hydrogen 3.287 N/A ASN 381.A N ASP 20.A OD2 no hydrogen 2.850 N/A ASN 381.A ND2 SER 19.A OG no hydrogen 3.416 N/A ARG 382.A NE PHE 132.A O no hydrogen 3.015 N/A ARG 382.A NH2 PHE 132.A O no hydrogen 2.944 N/A ARG 383.A N TYR 378.A OH no hydrogen 3.147 N/A