Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6ed6_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N GLN 1.A O no hydrogen 3.435 N/A LEU 7.A N LYS 3.A O no hydrogen 2.799 N/A ILE 8.A N LEU 4.A O no hydrogen 3.150 N/A ARG 9.A N ALA 6.A O no hydrogen 3.127 N/A ASP 10.A N ALA 6.A O no hydrogen 2.865 N/A SER 13.A N ASP 10.A O no hydrogen 3.243 N/A SER 13.A OG LEU 7.A O no hydrogen 2.738 N/A ILE 15.A N SER 13.A OG no hydrogen 3.112 N/A ASN 16.A ND2 ASP 10.A O no hydrogen 3.177 N/A SER 19.A N ASN 16.A OD1 no hydrogen 3.216 N/A SER 19.A OG ASN 16.A OD1 no hydrogen 3.224 N/A LEU 20.A N ASN 16.A O no hydrogen 2.943 N/A LEU 21.A N VAL 17.A O no hydrogen 2.822 N/A ASP 22.A N GLU 18.A O no hydrogen 2.826 N/A GLY 23.A N SER 19.A O no hydrogen 2.890 N/A LEU 24.A N LEU 21.A O no hydrogen 3.167 N/A ASN 25.A N LEU 21.A O no hydrogen 3.019 N/A SER 26.A N ASP 22.A O no hydrogen 2.867 N/A SER 26.A OG ASP 30.A OD2 no hydrogen 3.469 N/A LEU 27.A N GLY 23.A O no hydrogen 3.273 N/A VAL 28.A N LEU 24.A O no hydrogen 3.053 N/A LEU 29.A N ASN 25.A O no hydrogen 2.852 N/A ASP 30.A N SER 26.A O no hydrogen 2.925 N/A LEU 31.A N LEU 27.A O no hydrogen 3.233 N/A ASP 32.A N VAL 28.A O no hydrogen 3.104 N/A PHE 33.A N LEU 31.A O no hydrogen 2.811 N/A LEU 36.A N PHE 33.A O no hydrogen 2.822 N/A ARG 37.A N PHE 33.A O no hydrogen 2.769 N/A ARG 37.A NE ASP 32.A OD1 no hydrogen 3.338 N/A ARG 37.A NH1 ASN 47.A OD1 no hydrogen 3.154 N/A ARG 37.A NH2 ASP 32.A OD1 no hydrogen 3.526 N/A ASN 39.A N LEU 36.A O no hydrogen 3.207 N/A ASN 41.A N ASN 39.A OD1 no hydrogen 2.792 N/A ILE 42.A N ASN 39.A OD1 no hydrogen 3.362 N/A ASP 43.A N ASN 39.A O no hydrogen 3.003 N/A ASN 44.A N LYS 40.A O no hydrogen 2.865 N/A PHE 45.A N ASN 41.A O no hydrogen 3.155 N/A LEU 46.A N ILE 42.A O no hydrogen 3.012 N/A ASN 47.A N ASP 43.A O no hydrogen 2.770 N/A ARG 48.A N ASN 44.A O no hydrogen 3.046 N/A TYR 49.A N PHE 45.A O no hydrogen 3.062 N/A GLU 50.A N LEU 46.A O no hydrogen 2.692 N/A VAL 53.A N TYR 49.A O no hydrogen 2.826 N/A LYS 54.A N GLU 50.A O no hydrogen 2.955 N/A LYS 55.A N LYS 51.A O no hydrogen 3.398 N/A ILE 56.A N ILE 52.A O no hydrogen 2.966 N/A ARG 57.A N VAL 53.A O no hydrogen 2.927 N/A LEU 59.A N LYS 55.A O no hydrogen 3.231 N/A GLN 60.A N ILE 56.A O no hydrogen 2.775 N/A GLN 60.A NE2 ASN 25.A OD1 no hydrogen 3.454 N/A LYS 62.A NZ GLY 58.A O no hydrogen 2.807 N/A LYS 62.A NZ ASP 65.A OD1 no hydrogen 3.038 N/A ASP 65.A N LYS 62.A O no hydrogen 3.150 N/A TYR 66.A N ALA 63.A O no hydrogen 3.174 N/A ASP 67.A N ARG 84.A O no hydrogen 2.845 N/A LYS 70.A N LEU 82.A O no hydrogen 3.373 N/A LYS 70.A NZ ASP 355.A O no hydrogen 3.367 N/A ILE 72.A N VAL 80.A O no hydrogen 3.010 N/A GLY 73.A N VAL 80.A O no hydrogen 3.182 N/A GLY 75.A N GLY 78.A O no hydrogen 2.700 N/A GLY 78.A N GLY 75.A O no hydrogen 3.312 N/A VAL 80.A N GLY 73.A O no hydrogen 2.966 N/A GLN 81.A N MET 94.A O no hydrogen 2.831 N/A LEU 82.A N LYS 70.A O no hydrogen 2.765 N/A VAL 83.A N TYR 92.A O no hydrogen 2.861 N/A ARG 84.A N ASP 67.A O no hydrogen 3.052 N/A ARG 84.A NE GLN 89.A O no hydrogen 2.798 N/A ARG 84.A NH2 ASP 348.A OD1 no hydrogen 3.016 N/A HIS 85.A N LYS 90.A O no hydrogen 2.840 N/A HIS 85.A ND1 SER 88.A OG no hydrogen 2.869 N/A LYS 86.A N ASP 65.A O no hydrogen 2.840 N/A LYS 86.A NZ GLU 64.A O no hydrogen 2.832 N/A SER 88.A N HIS 85.A ND1 no hydrogen 3.228 N/A SER 88.A OG HIS 85.A ND1 no hydrogen 2.869 N/A SER 88.A OG HIS 85.A O no hydrogen 3.445 N/A GLN 89.A N HIS 85.A O no hydrogen 2.646 N/A TYR 92.A N VAL 83.A O no hydrogen 3.023 N/A ALA 93.A N MET 143.A O no hydrogen 2.900 N/A MET 94.A N GLN 81.A O no hydrogen 2.849 N/A LYS 95.A N MET 141.A O no hydrogen 2.915 N/A LYS 95.A NZ GLU 114.A OE1 no hydrogen 3.201 N/A LYS 95.A NZ GLU 114.A OE2 no hydrogen 2.744 N/A LEU 96.A N GLU 79.A O no hydrogen 2.921 N/A LEU 97.A N LEU 139.A O no hydrogen 3.067 N/A SER 98.A N PHE 77.A O no hydrogen 2.791 N/A LYS 99.A N ARG 137.A O no hydrogen 3.079 N/A LYS 99.A NZ GLN 134.A OE1 no hydrogen 3.096 N/A LYS 99.A NZ ASP 135.A O no hydrogen 2.760 N/A LYS 99.A NZ GLN 370.A OE1 no hydrogen 3.288 N/A GLU 101.A N SER 98.A OG no hydrogen 3.091 N/A MET 102.A N SER 98.A O no hydrogen 3.101 N/A MET 102.A N LYS 99.A O no hydrogen 3.004 N/A ILE 103.A N LYS 99.A O no hydrogen 3.097 N/A ILE 103.A N PHE 100.A O no hydrogen 3.329 N/A LYS 104.A N PHE 100.A O no hydrogen 2.920 N/A LYS 104.A NZ GLU 101.A OE2 no hydrogen 3.553 N/A ARG 105.A N GLU 101.A O no hydrogen 3.133 N/A ARG 105.A NE GLU 101.A OE1 no hydrogen 3.447 N/A SER 106.A N ILE 103.A O no hydrogen 3.260 N/A ASP 107.A N ARG 105.A O no hydrogen 2.720 N/A GLU 114.A N PHE 110.A O no hydrogen 3.516 N/A ARG 115.A N PHE 111.A O no hydrogen 2.849 N/A ARG 115.A NE PHE 376.A O no hydrogen 2.743 N/A ARG 115.A NH2 PHE 376.A O no hydrogen 3.247 N/A ASP 116.A N TRP 112.A O no hydrogen 3.109 N/A ILE 117.A N GLU 113.A O no hydrogen 2.816 N/A MET 118.A N GLU 114.A O no hydrogen 3.292 N/A ALA 119.A N ARG 115.A O no hydrogen 2.764 N/A PHE 120.A N ASP 116.A O no hydrogen 3.000 N/A ALA 121.A N ILE 117.A O no hydrogen 2.803 N/A TRP 125.A N SER 123.A OG no hydrogen 3.133 N/A VAL 126.A N SER 123.A O no hydrogen 3.192 N/A VAL 127.A N LEU 204.A O no hydrogen 3.275 N/A GLN 128.A N GLU 144.A OE2 no hydrogen 3.471 N/A LEU 129.A N MET 118.A O no hydrogen 3.115 N/A PHE 130.A N VAL 142.A O no hydrogen 2.861 N/A TYR 131.A N VAL 142.A O no hydrogen 3.380 N/A ALA 132.A N TYR 378.A O no hydrogen 3.450 N/A PHE 133.A N TYR 140.A O no hydrogen 3.006 N/A GLN 134.A NE2 PHE 373.A O no hydrogen 2.996 N/A ASP 135.A N TYR 138.A O no hydrogen 3.028 N/A ARG 137.A N ASP 135.A OD1 no hydrogen 3.146 N/A TYR 138.A N ASP 135.A OD1 no hydrogen 2.805 N/A LEU 139.A N LEU 97.A O no hydrogen 2.962 N/A TYR 140.A N PHE 133.A O no hydrogen 2.868 N/A TYR 140.A OH ASP 135.A OD2 no hydrogen 2.844 N/A MET 141.A N LYS 95.A O no hydrogen 2.883 N/A VAL 142.A N TYR 131.A O no hydrogen 2.770 N/A MET 143.A N ALA 93.A O no hydrogen 2.771 N/A GLU 144.A N GLN 128.A O no hydrogen 3.030 N/A TYR 145.A OH ASP 350.A O no hydrogen 2.614 N/A GLY 148.A N LEU 196.A O no hydrogen 2.958 N/A GLY 149.A N MET 146.A O no hydrogen 3.343 N/A LEU 151.A N PRO 191.A O no hydrogen 3.321 N/A LEU 151.A N MET 194.A O no hydrogen 3.161 N/A ASN 153.A N ASP 150.A OD1 no hydrogen 3.006 N/A LEU 154.A N ASP 150.A O no hydrogen 3.349 N/A MET 155.A N LEU 151.A O no hydrogen 3.174 N/A SER 156.A N VAL 152.A O no hydrogen 3.094 N/A SER 156.A OG ASN 153.A O no hydrogen 2.772 N/A ASN 157.A N ASN 153.A O no hydrogen 3.038 N/A ASN 157.A N LEU 154.A O no hydrogen 3.254 N/A TYR 158.A N MET 155.A O no hydrogen 3.437 N/A TRP 164.A N PRO 161.A O no hydrogen 2.837 N/A ALA 165.A N PRO 161.A O no hydrogen 3.137 N/A LYS 166.A N GLU 162.A O no hydrogen 3.063 N/A LYS 166.A NZ PHE 323.A O no hydrogen 3.377 N/A LYS 166.A NZ LYS 325.A O no hydrogen 2.918 N/A TYR 168.A N TRP 164.A O no hydrogen 3.019 N/A THR 169.A N ALA 165.A O no hydrogen 2.950 N/A THR 169.A OG1 ALA 165.A O no hydrogen 2.727 N/A ALA 170.A N LYS 166.A O no hydrogen 3.140 N/A GLU 171.A N PHE 167.A O no hydrogen 2.975 N/A VAL 172.A N TYR 168.A O no hydrogen 3.008 N/A VAL 173.A N THR 169.A O no hydrogen 2.860 N/A LEU 174.A N ALA 170.A O no hydrogen 3.063 N/A ALA 175.A N GLU 171.A O no hydrogen 2.929 N/A LEU 176.A N VAL 172.A O no hydrogen 2.888 N/A ASP 177.A N VAL 173.A O no hydrogen 2.788 N/A ALA 178.A N LEU 174.A O no hydrogen 3.130 N/A ILE 179.A N ALA 175.A O no hydrogen 3.144 N/A HIS 180.A N LEU 176.A O no hydrogen 2.854 N/A HIS 180.A NE2 ASP 246.A OD2 no hydrogen 2.777 N/A SER 181.A N ASP 177.A O no hydrogen 3.007 N/A SER 181.A OG ASP 177.A O no hydrogen 3.546 N/A SER 181.A OG ALA 178.A O no hydrogen 3.087 N/A MET 182.A N ILE 179.A O no hydrogen 3.267 N/A GLY 183.A N HIS 180.A O no hydrogen 2.812 N/A LEU 184.A N ILE 179.A O no hydrogen 3.227 N/A ILE 185.A N MET 211.A O no hydrogen 3.439 N/A HIS 186.A N ASP 246.A OD2 no hydrogen 2.901 N/A ARG 187.A N ASP 246.A OD1 no hydrogen 2.878 N/A ARG 187.A NE TYR 241.A OH no hydrogen 3.418 N/A ARG 187.A NH1 THR 209.A O no hydrogen 2.661 N/A ARG 187.A NH2 TYR 241.A OH no hydrogen 3.376 N/A ASP 188.A N HIS 186.A ND1 no hydrogen 3.178 N/A LYS 190.A NZ THR 227.A OG1 no hydrogen 2.817 N/A ASN 193.A N LYS 190.A O no hydrogen 2.868 N/A MET 194.A N PRO 191.A O no hydrogen 3.050 N/A LEU 195.A N LYS 203.A O no hydrogen 2.813 N/A LEU 196.A N GLY 149.A O no hydrogen 2.759 N/A ASP 197.A N HIS 201.A O no hydrogen 2.943 N/A HIS 199.A N ASP 197.A OD1 no hydrogen 3.291 N/A GLY 200.A N ASP 197.A O no hydrogen 2.817 N/A HIS 201.A N ASP 197.A OD1 no hydrogen 2.817 N/A HIS 201.A ND1 GLU 171.A OE1 no hydrogen 3.257 N/A HIS 201.A ND1 GLU 171.A OE2 no hydrogen 2.739 N/A HIS 201.A NE2 THR 337.A O no hydrogen 2.809 N/A LEU 202.A N GLU 171.A OE1 no hydrogen 2.812 N/A LYS 203.A N LEU 195.A O no hydrogen 2.848 N/A LYS 203.A NZ PRO 124.A O no hydrogen 2.729 N/A LEU 204.A N TRP 125.A O no hydrogen 2.791 N/A ALA 205.A N ASN 193.A O no hydrogen 3.073 N/A THR 209.A OG1 HIS 186.A O no hydrogen 2.729 N/A CYS 210.A SG ILE 185.A O no hydrogen 3.794 N/A CYS 210.A SG HIS 186.A O no hydrogen 3.856 N/A MET 213.A N GLY 183.A O no hydrogen 3.150 N/A ASP 214.A N MET 218.A O no hydrogen 2.749 N/A GLY 217.A N ASP 214.A O no hydrogen 3.460 N/A VAL 219.A N TYR 241.A O no hydrogen 3.059 N/A CYS 221.A SG THR 223.A OG1 no hydrogen 3.614 N/A ALA 224.A N GLN 239.A OE1 no hydrogen 2.922 N/A THR 227.A OG1 ASP 188.A OD1 no hydrogen 2.742 N/A TYR 230.A N THR 227.A O no hydrogen 3.015 N/A TYR 230.A OH GLU 256.A OE1 no hydrogen 2.672 N/A ILE 231.A N THR 227.A O no hydrogen 3.039 N/A ILE 231.A N PRO 228.A O no hydrogen 3.227 N/A LEU 236.A N SER 232.A O no hydrogen 3.460 N/A LYS 237.A N PRO 233.A O no hydrogen 2.796 N/A SER 238.A N VAL 235.A O no hydrogen 3.149 N/A SER 238.A OG VAL 235.A O no hydrogen 2.834 N/A GLN 239.A N LEU 236.A O no hydrogen 3.328 N/A TYR 241.A N VAL 219.A O no hydrogen 3.356 N/A GLY 242.A N GLU 244.A OE2 no hydrogen 2.897 N/A CYS 245.A N GLY 242.A O no hydrogen 3.461 N/A CYS 245.A SG GLY 242.A O no hydrogen 3.392 N/A ASP 246.A N ARG 243.A O no hydrogen 3.323 N/A TRP 248.A N GLU 244.A O no hydrogen 3.413 N/A SER 249.A OG TYR 230.A O no hydrogen 3.227 N/A VAL 250.A N ASP 246.A O no hydrogen 3.345 N/A GLY 251.A N TRP 247.A O no hydrogen 3.200 N/A VAL 252.A N TRP 248.A O no hydrogen 3.236 N/A PHE 253.A N SER 249.A O no hydrogen 2.869 N/A LEU 254.A N VAL 250.A O no hydrogen 2.934 N/A TYR 255.A N GLY 251.A O no hydrogen 2.973 N/A TYR 255.A OH CYS 284.A O no hydrogen 3.109 N/A GLU 256.A N VAL 252.A O no hydrogen 2.913 N/A MET 257.A N PHE 253.A O no hydrogen 3.008 N/A LEU 258.A N LEU 254.A O no hydrogen 3.069 N/A VAL 259.A N TYR 255.A O no hydrogen 2.866 N/A GLY 260.A N GLU 256.A O no hydrogen 2.861 N/A THR 262.A OG1 ASP 229.A OD2 no hydrogen 3.031 N/A TYR 265.A N THR 262.A O no hydrogen 3.510 N/A GLY 271.A N SER 268.A OG no hydrogen 2.845 N/A THR 272.A N SER 268.A O no hydrogen 3.170 N/A THR 272.A OG1 SER 268.A O no hydrogen 3.289 N/A TYR 273.A N LEU 269.A O no hydrogen 3.227 N/A SER 274.A N VAL 270.A O no hydrogen 2.858 N/A LYS 275.A N GLY 271.A O no hydrogen 2.848 N/A LYS 275.A NZ TYR 265.A O no hydrogen 2.958 N/A ILE 276.A N THR 272.A O no hydrogen 2.908 N/A MET 277.A N TYR 273.A O no hydrogen 3.150 N/A ASP 278.A N LYS 275.A O no hydrogen 3.062 N/A HIS 279.A N ILE 276.A O no hydrogen 2.949 N/A HIS 279.A NE2 ASP 305.A OD1 no hydrogen 3.304 N/A ASN 281.A N ASP 278.A O no hydrogen 3.008 N/A ASN 281.A ND2 ASP 278.A OD1 no hydrogen 3.148 N/A SER 282.A N ASP 278.A O no hydrogen 2.793 N/A SER 282.A OG LYS 275.A O no hydrogen 2.628 N/A SER 282.A OG ASP 278.A O no hydrogen 2.729 N/A LEU 283.A N HIS 279.A O no hydrogen 3.071 N/A ALA 289.A N PRO 286.A O no hydrogen 3.256 N/A SER 292.A N GLU 162.A OE2 no hydrogen 2.877 N/A SER 292.A OG GLU 162.A OE1 no hydrogen 2.693 N/A SER 292.A OG GLU 162.A OE2 no hydrogen 3.295 N/A ALA 295.A N SER 292.A OG no hydrogen 2.997 N/A LYS 296.A N SER 292.A O no hydrogen 3.153 N/A ASN 297.A N LYS 293.A O no hydrogen 2.984 N/A LEU 298.A N HIS 294.A O no hydrogen 3.212 N/A ILE 299.A N ALA 295.A O no hydrogen 3.039 N/A CYS 300.A N LYS 296.A O no hydrogen 3.045 N/A CYS 300.A SG LYS 296.A O no hydrogen 3.252 N/A ALA 301.A N ASN 297.A O no hydrogen 2.753 N/A PHE 302.A N LEU 298.A O no hydrogen 3.254 N/A PHE 302.A N ILE 299.A O no hydrogen 3.319 N/A LEU 303.A N ILE 299.A O no hydrogen 2.813 N/A THR 304.A OG1 ASP 305.A O no hydrogen 3.345 N/A ARG 306.A NH1 PHE 240.A O no hydrogen 2.840 N/A GLU 307.A N GLU 307.A OE2 no hydrogen 3.005 N/A VAL 308.A N ASP 305.A O no hydrogen 3.090 N/A ARG 309.A NE PHE 302.A O no hydrogen 2.983 N/A ARG 309.A NE THR 304.A O no hydrogen 3.096 N/A ARG 309.A NH1 GLU 234.A OE1 no hydrogen 2.953 N/A ARG 309.A NH1 GLU 234.A OE2 no hydrogen 3.106 N/A ARG 309.A NH1 GLU 244.A O no hydrogen 2.952 N/A ARG 309.A NH2 GLU 234.A OE1 no hydrogen 2.810 N/A ARG 309.A NH2 THR 304.A O no hydrogen 2.840 N/A LEU 310.A N ALA 301.A O no hydrogen 2.804 N/A GLY 311.A N GLU 317.A OE2 no hydrogen 2.826 N/A ARG 312.A N ARG 309.A O no hydrogen 3.204 N/A ARG 312.A NE ARG 309.A O no hydrogen 2.811 N/A ASN 313.A N GLU 317.A OE2 no hydrogen 3.003 N/A ASN 313.A ND2 GLU 317.A OE1 no hydrogen 3.227 N/A GLY 314.A N GLY 311.A O no hydrogen 2.844 N/A ARG 319.A N VAL 315.A O no hydrogen 2.929 N/A GLN 320.A N GLU 316.A O no hydrogen 3.178 N/A HIS 321.A N ILE 318.A O no hydrogen 2.976 N/A HIS 321.A NE2 ASN 297.A OD1 no hydrogen 2.859 N/A PHE 323.A N HIS 321.A ND1 no hydrogen 2.869 N/A PHE 324.A N HIS 321.A O no hydrogen 3.059 N/A LYS 325.A N PRO 322.A O no hydrogen 2.947 N/A ASN 326.A ND2 PHE 324.A O no hydrogen 2.975 N/A ASN 326.A ND2 TRP 329.A O no hydrogen 3.377 N/A GLN 328.A N ASN 326.A OD1 no hydrogen 2.870 N/A TRP 329.A N ASN 326.A OD1 no hydrogen 2.676 N/A HIS 330.A N ASN 333.A OD1 no hydrogen 2.837 N/A ASN 333.A N HIS 330.A O no hydrogen 3.175 N/A ILE 334.A N HIS 330.A O no hydrogen 3.084 N/A GLU 336.A N ASN 333.A O no hydrogen 2.738 N/A THR 337.A N ASN 333.A O no hydrogen 3.198 N/A THR 337.A N ILE 334.A O no hydrogen 3.044 N/A THR 337.A OG1 ILE 334.A O no hydrogen 2.888 N/A SER 346.A N ASP 350.A OD2 no hydrogen 2.709 N/A SER 346.A OG ASP 350.A OD2 no hydrogen 3.296 N/A ASP 350.A N SER 347.A O no hydrogen 3.200 N/A SER 352.A N ASP 350.A OD1 no hydrogen 2.920 N/A SER 352.A OG ASP 350.A OD1 no hydrogen 2.699 N/A ASN 353.A ND2 PRO 147.A O no hydrogen 2.821 N/A PHE 354.A N SER 351.A O no hydrogen 3.306 N/A GLN 370.A N ASP 30.A OD1 no hydrogen 3.335 N/A LEU 371.A N GLY 368.A O no hydrogen 3.113 N/A PHE 373.A N GLN 370.A O no hydrogen 3.066 N/A ILE 374.A N LEU 371.A O no hydrogen 3.154 N/A GLY 375.A N ASP 22.A OD2 no hydrogen 3.085 N/A PHE 376.A N PHE 373.A O no hydrogen 3.313 N/A THR 377.A N ASP 22.A OD2 no hydrogen 3.079 N/A THR 377.A OG1 ASP 22.A OD1 no hydrogen 2.852 N/A THR 377.A OG1 ASP 22.A OD2 no hydrogen 3.421 N/A TYR 378.A N ALA 132.A O no hydrogen 2.795 N/A