Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6epc_J.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N SER 18.A O no hydrogen 3.181 N/A SER 18.A N GLY 14.A O no hydrogen 3.169 N/A GLY 19.A N LYS 15.A O no hydrogen 2.910 N/A LEU 20.A N ALA 16.A O no hydrogen 2.864 N/A ARG 21.A N SER 18.A O no hydrogen 2.935 N/A GLN 22.A N GLY 19.A O no hydrogen 3.052 N/A TYR 24.A N LEU 20.A O no hydrogen 2.702 N/A LEU 25.A N ARG 21.A O no hydrogen 2.951 N/A SER 26.A N GLN 22.A O no hydrogen 3.146 N/A LYS 27.A N TYR 23.A O no hydrogen 3.286 N/A LYS 27.A N TYR 24.A O no hydrogen 3.221 N/A ILE 28.A N TYR 24.A O no hydrogen 3.453 N/A GLU 29.A N LEU 25.A O no hydrogen 3.029 N/A GLU 30.A N SER 26.A O no hydrogen 2.966 N/A LEU 31.A N LYS 27.A O no hydrogen 3.110 N/A GLN 32.A N ILE 28.A O no hydrogen 2.736 N/A VAL 35.A N LEU 31.A O no hydrogen 3.175 N/A ASN 36.A N GLN 32.A O no hydrogen 3.215 N/A ASN 36.A ND2 GLN 32.A O no hydrogen 3.281 N/A LYS 38.A N ILE 34.A O no hydrogen 3.061 N/A SER 39.A N VAL 35.A O no hydrogen 3.198 N/A SER 39.A OG ASN 36.A O no hydrogen 2.812 N/A GLN 40.A N ASN 36.A O no hydrogen 3.181 N/A ASN 41.A N ASP 37.A O no hydrogen 2.892 N/A LEU 42.A N LYS 38.A O no hydrogen 3.027 N/A ARG 43.A N SER 39.A O no hydrogen 3.044 N/A ARG 44.A N GLN 40.A O no hydrogen 3.123 N/A ARG 44.A N ASN 41.A O no hydrogen 3.209 N/A LEU 45.A N ASN 41.A O no hydrogen 3.380 N/A GLN 46.A N LEU 42.A O no hydrogen 3.050 N/A GLN 46.A NE2 ASN 50.A OD1 no hydrogen 3.689 N/A ALA 47.A N ARG 43.A O no hydrogen 2.947 N/A GLN 48.A N ARG 44.A O no hydrogen 3.389 N/A ARG 49.A N LEU 45.A O no hydrogen 2.990 N/A ASN 50.A N GLN 46.A O no hydrogen 2.846 N/A GLU 51.A N ALA 47.A O no hydrogen 3.353 N/A LEU 52.A N GLN 48.A O no hydrogen 3.269 N/A ASN 53.A N ARG 49.A O no hydrogen 3.036 N/A ALA 54.A N ASN 50.A O no hydrogen 3.119 N/A ARG 57.A N ASN 53.A O no hydrogen 3.042 N/A LEU 58.A N ALA 54.A O no hydrogen 3.121 N/A LEU 59.A N LYS 55.A O no hydrogen 2.911 N/A LEU 59.A N VAL 56.A O no hydrogen 3.162 N/A GLU 62.A N LEU 58.A O no hydrogen 3.125 N/A LEU 65.A N GLU 61.A O no hydrogen 3.081 N/A LEU 66.A N GLU 62.A O no hydrogen 2.807 N/A GLN 67.A N LEU 63.A O no hydrogen 2.993 N/A GLN 69.A NE2 ASN 118.A O no hydrogen 3.446 N/A SER 71.A OG GLU 68.A OE1 no hydrogen 3.120 N/A SER 71.A OG GLY 70.A O no hydrogen 3.106 N/A TYR 72.A N LEU 116.A O no hydrogen 3.211 N/A GLY 74.A N VAL 114.A O no hydrogen 3.239 N/A GLU 75.A N LYS 88.A O no hydrogen 3.206 N/A VAL 76.A N CYS 112.A O no hydrogen 3.205 N/A VAL 77.A N LEU 86.A O no hydrogen 3.083 N/A VAL 85.A N VAL 97.A O no hydrogen 2.835 N/A LEU 86.A N ARG 78.A O no hydrogen 3.064 N/A VAL 87.A N PHE 95.A O no hydrogen 3.134 N/A LYS 88.A N GLU 75.A O no hydrogen 3.125 N/A HIS 90.A N VAL 73.A O no hydrogen 3.492 N/A PHE 95.A N VAL 87.A O no hydrogen 2.915 N/A VAL 97.A N VAL 85.A O no hydrogen 3.307 N/A VAL 99.A N LYS 83.A O no hydrogen 3.336 N/A LYS 101.A NZ ASP 100.A OD1 no hydrogen 3.413 N/A ASN 102.A N ASP 100.A OD2 no hydrogen 3.309 N/A ASP 104.A N ASP 107.A OD2 no hydrogen 2.903 N/A ASN 106.A N ASP 104.A OD2 no hydrogen 3.263 N/A ASN 111.A N VAL 76.A O no hydrogen 2.930 N/A CYS 112.A SG ARG 113.A O no hydrogen 3.623 N/A CYS 112.A SG LEU 127.A O no hydrogen 3.524 N/A ARG 113.A NE ASN 129.A OD1 no hydrogen 3.355 N/A VAL 114.A N GLY 74.A O no hydrogen 3.195 N/A ALA 115.A N LYS 125.A O no hydrogen 3.375 N/A LEU 116.A N TYR 72.A O no hydrogen 3.033 N/A ARG 117.A N THR 122.A O no hydrogen 3.155 N/A ARG 117.A NH1 GLU 68.A OE1 no hydrogen 3.049 N/A ASN 118.A N GLY 70.A O no hydrogen 3.189 N/A TYR 121.A N ARG 117.A O no hydrogen 2.971 N/A HIS 124.A N ALA 115.A O no hydrogen 3.421 N/A LYS 125.A NZ ILE 126.A O no hydrogen 3.414 N/A LEU 127.A N ARG 113.A O no hydrogen 3.256 N/A VAL 131.A N ASN 111.A O no hydrogen 3.377 N/A LEU 137.A N PRO 133.A O no hydrogen 3.383 N/A MET 138.A N LEU 134.A O no hydrogen 3.276 N/A MET 139.A N VAL 135.A O no hydrogen 3.444 N/A VAL 140.A N SER 136.A O no hydrogen 3.177 N/A GLU 141.A N LEU 137.A O no hydrogen 3.146 N/A TYR 148.A OH GLU 166.A OE1 no hydrogen 2.852 N/A MET 150.A N THR 147.A O no hydrogen 3.162 N/A ILE 151.A N THR 147.A O no hydrogen 3.487 N/A GLY 152.A N TYR 148.A O no hydrogen 3.041 N/A GLY 152.A N GLU 149.A O no hydrogen 3.249 N/A LYS 156.A NZ GLU 160.A OE1 no hydrogen 3.250 N/A GLN 157.A NE2 GLU 160.A OE1 no hydrogen 3.174 N/A ILE 158.A N LEU 154.A O no hydrogen 3.048 N/A ILE 161.A N GLN 157.A O no hydrogen 3.224 N/A LYS 162.A N ILE 158.A O no hydrogen 3.114 N/A ILE 165.A N ILE 161.A O no hydrogen 3.272 N/A GLU 166.A N LYS 162.A O no hydrogen 3.169 N/A LYS 170.A N GLU 166.A O no hydrogen 2.998 N/A HIS 171.A N LEU 167.A O no hydrogen 3.179 N/A GLU 176.A N PRO 172.A O no hydrogen 2.968 N/A ALA 177.A N GLU 173.A O no hydrogen 2.939 N/A LEU 178.A N LEU 174.A O no hydrogen 3.177 N/A GLY 179.A N PHE 175.A O no hydrogen 3.292 N/A ILE 180.A N PHE 175.A O no hydrogen 3.388 N/A GLN 182.A NE2 ALA 285.A O no hydrogen 3.082 N/A LYS 184.A N ARG 310.A O no hydrogen 2.977 N/A LYS 184.A NZ ASN 278.A O no hydrogen 3.473 N/A LYS 184.A NZ GLU 284.A O no hydrogen 3.062 N/A LEU 188.A N MET 293.A O no hydrogen 3.089 N/A TYR 189.A N ILE 315.A O no hydrogen 2.941 N/A TYR 189.A OH GLU 316.A OE1 no hydrogen 3.184 N/A THR 194.A OG1 PRO 318.A O no hydrogen 2.848 N/A LEU 199.A N GLY 195.A O no hydrogen 3.430 N/A ALA 200.A N LYS 196.A O no hydrogen 3.263 N/A ARG 201.A N THR 197.A O no hydrogen 3.448 N/A ARG 201.A NE THR 197.A O no hydrogen 3.100 N/A ALA 202.A N LEU 198.A O no hydrogen 3.136 N/A VAL 203.A N LEU 199.A O no hydrogen 3.055 N/A HIS 205.A N ARG 201.A O no hydrogen 3.253 N/A HIS 206.A N ALA 202.A O no hydrogen 3.055 N/A THR 207.A N VAL 203.A O no hydrogen 2.988 N/A THR 207.A OG1 VAL 203.A O no hydrogen 3.087 N/A THR 207.A OG1 ALA 204.A O no hydrogen 3.081 N/A CYS 209.A N ALA 204.A O no hydrogen 3.393 N/A CYS 209.A SG THR 207.A OG1 no hydrogen 3.192 N/A THR 210.A OG1 SER 244.A OG no hydrogen 2.984 N/A ILE 212.A N ILE 245.A O no hydrogen 3.298 N/A ARG 213.A NH2 ASP 249.A OD2 no hydrogen 3.101 N/A VAL 214.A N PHE 247.A O no hydrogen 3.049 N/A SER 215.A OG ASP 266.A OD2 no hydrogen 3.257 N/A GLY 227.A N GLN 221.A OE1 no hydrogen 3.184 N/A PHE 235.A N VAL 231.A O no hydrogen 3.346 N/A MET 237.A N GLU 233.A O no hydrogen 3.382 N/A ALA 238.A N LEU 234.A O no hydrogen 2.890 N/A ARG 239.A N PHE 235.A O no hydrogen 2.981 N/A GLU 240.A N VAL 236.A O no hydrogen 3.269 N/A GLU 240.A N MET 237.A O no hydrogen 3.182 N/A HIS 241.A N ALA 238.A O no hydrogen 3.199 N/A ALA 242.A N ARG 239.A O no hydrogen 3.152 N/A SER 244.A N ASN 288.A O no hydrogen 3.327 N/A SER 244.A OG THR 210.A OG1 no hydrogen 2.984 N/A SER 244.A OG ALA 238.A O no hydrogen 2.997 N/A SER 244.A OG HIS 241.A O no hydrogen 3.402 N/A ILE 245.A N THR 210.A O no hydrogen 3.173 N/A ILE 246.A N LYS 290.A O no hydrogen 3.021 N/A PHE 247.A N ILE 212.A O no hydrogen 2.891 N/A MET 248.A N ILE 292.A O no hydrogen 3.009 N/A ARG 258.A NH1 SER 215.A O no hydrogen 2.958 N/A ARG 258.A NH2 SER 215.A O no hydrogen 3.023 N/A ARG 258.A NH2 SER 215.A OG no hydrogen 2.950 N/A SER 267.A OG SER 263.A O no hydrogen 3.031 N/A SER 267.A OG GLY 264.A O no hydrogen 3.265 N/A SER 267.A OG ILE 300.A O no hydrogen 3.393 N/A GLN 270.A N ASP 266.A O no hydrogen 3.364 N/A ARG 271.A N SER 267.A O no hydrogen 3.013 N/A THR 272.A N GLU 268.A O no hydrogen 3.150 N/A THR 272.A OG1 GLU 268.A O no hydrogen 3.140 N/A THR 272.A OG1 VAL 269.A O no hydrogen 2.787 N/A MET 273.A N VAL 269.A O no hydrogen 3.101 N/A LEU 274.A N GLN 270.A O no hydrogen 3.106 N/A GLU 275.A N ARG 271.A O no hydrogen 3.252 N/A LEU 276.A N THR 272.A O no hydrogen 3.346 N/A LEU 277.A N MET 273.A O no hydrogen 2.991 N/A ASN 278.A N LEU 274.A O no hydrogen 2.980 N/A ASN 278.A N GLU 275.A O no hydrogen 3.257 N/A GLN 279.A N LEU 276.A O no hydrogen 3.240 N/A GLN 279.A NE2 ASP 281.A O no hydrogen 3.037 N/A THR 286.A OG1 GLU 176.A OE1 no hydrogen 3.335 N/A LYS 287.A NZ PHE 283.A O no hydrogen 3.441 N/A LYS 287.A NZ THR 286.A O no hydrogen 3.104 N/A ASN 288.A ND2 VAL 169.A O no hydrogen 3.354 N/A LYS 290.A N SER 244.A O no hydrogen 3.353 N/A LYS 290.A NZ ILE 165.A O no hydrogen 3.454 N/A ILE 292.A N ILE 246.A O no hydrogen 3.291 N/A MET 293.A N VAL 186.A O no hydrogen 3.290 N/A ALA 294.A N MET 248.A O no hydrogen 3.293 N/A THR 295.A N LEU 188.A O no hydrogen 3.113 N/A THR 295.A OG1 LEU 188.A O no hydrogen 3.444 N/A THR 295.A OG1 ARG 297.A O no hydrogen 3.409 N/A ASN 296.A ND2 ASP 252.A OD1 no hydrogen 3.435 N/A ASN 296.A ND2 ASP 252.A OD2 no hydrogen 3.530 N/A LEU 305.A N ASP 302.A O no hydrogen 3.110 N/A LEU 306.A N ASP 302.A O no hydrogen 3.424 N/A ARG 307.A N SER 303.A O no hydrogen 3.342 N/A ARG 307.A NE SER 303.A O no hydrogen 3.377 N/A ARG 310.A NH2 GLU 275.A OE1 no hydrogen 2.974 N/A ARG 310.A NH2 GLU 275.A OE2 no hydrogen 3.266 N/A LYS 314.A NZ LEU 305.A O no hydrogen 3.177 N/A ILE 315.A N LEU 187.A O no hydrogen 2.880 N/A PHE 317.A N TYR 189.A O no hydrogen 3.081 N/A ARG 325.A N ASN 321.A O no hydrogen 3.227 N/A ARG 325.A NH1 ALA 348.A O no hydrogen 2.859 N/A LEU 326.A N GLU 322.A O no hydrogen 3.247 N/A LEU 326.A N GLU 323.A O no hydrogen 3.360 N/A ASP 327.A N ALA 324.A O no hydrogen 3.227 N/A ILE 328.A N ALA 324.A O no hydrogen 3.383 N/A LEU 329.A N ARG 325.A O no hydrogen 3.119 N/A LYS 330.A N LEU 326.A O no hydrogen 2.944 N/A ILE 331.A N ASP 327.A O no hydrogen 3.423 N/A SER 333.A N LEU 329.A O no hydrogen 2.948 N/A SER 333.A OG LEU 329.A O no hydrogen 3.063 N/A ARG 334.A N LYS 330.A O no hydrogen 3.159 N/A LYS 335.A N HIS 332.A O no hydrogen 3.223 N/A MET 336.A N SER 333.A O no hydrogen 3.486 N/A ARG 345.A NH2 GLU 323.A OE2 no hydrogen 3.080 N/A LYS 346.A NZ GLU 384.A OE2 no hydrogen 3.273 N/A ILE 347.A N ASN 343.A O no hydrogen 3.399 N/A ALA 348.A N LEU 344.A O no hydrogen 3.222 N/A GLU 349.A N ARG 345.A O no hydrogen 3.073 N/A LEU 350.A N LYS 346.A O no hydrogen 3.235 N/A ALA 357.A N SER 355.A OG no hydrogen 3.221 N/A GLU 358.A N SER 355.A O no hydrogen 3.279 N/A LYS 360.A N GLY 356.A O no hydrogen 3.108 N/A GLY 361.A N ALA 357.A O no hydrogen 2.996 N/A VAL 362.A N VAL 359.A O no hydrogen 3.344 N/A THR 364.A N LYS 360.A O no hydrogen 3.298 N/A THR 364.A OG1 LYS 360.A O no hydrogen 3.130 N/A GLU 365.A N GLY 361.A O no hydrogen 3.044 N/A ALA 366.A N VAL 362.A O no hydrogen 3.341 N/A GLY 367.A N CYS 363.A O no hydrogen 3.255 N/A MET 368.A N THR 364.A O no hydrogen 3.049 N/A TYR 369.A N GLU 365.A O no hydrogen 2.963 N/A ALA 370.A N ALA 366.A O no hydrogen 2.983 N/A LEU 371.A N GLY 367.A O no hydrogen 3.030 N/A ARG 372.A N MET 368.A O no hydrogen 3.267 N/A GLU 373.A N TYR 369.A O no hydrogen 3.399 N/A ARG 374.A N LEU 371.A O no hydrogen 3.018 N/A ARG 375.A N ALA 370.A O no hydrogen 2.940 N/A ARG 375.A NE GLU 373.A OE2 no hydrogen 3.519 N/A ARG 375.A NH1 GLU 381.A OE1 no hydrogen 3.439 N/A ARG 375.A NH2 GLU 373.A OE1 no hydrogen 3.484 N/A VAL 378.A N ASN 337.A OD1 no hydrogen 3.416 N/A THR 379.A N ASP 382.A OD2 no hydrogen 3.022 N/A THR 379.A OG1 ASP 382.A OD2 no hydrogen 3.103 N/A MET 385.A N GLU 381.A O no hydrogen 3.240 N/A ALA 386.A N ASP 382.A O no hydrogen 3.055 N/A VAL 387.A N PHE 383.A O no hydrogen 2.821 N/A LYS 389.A N MET 385.A O no hydrogen 2.990 N/A LYS 389.A NZ GLU 365.A OE2 no hydrogen 3.276 N/A VAL 390.A N ALA 386.A O no hydrogen 3.032 N/A MET 391.A N VAL 387.A O no hydrogen 2.807 N/A GLN 392.A N ALA 388.A O no hydrogen 3.167 N/A LYS 393.A N LYS 389.A O no hydrogen 3.273 N/A ASP 394.A N VAL 390.A O no hydrogen 3.050 N/A SER 395.A N MET 391.A O no hydrogen 3.015 N/A SER 395.A OG MET 391.A O no hydrogen 3.265 N/A GLU 396.A N GLN 392.A O no hydrogen 3.175 N/A LYS 397.A N LYS 393.A O no hydrogen 3.333 N/A ASN 398.A N ASP 394.A O no hydrogen 2.963 N/A MET 399.A N SER 395.A O no hydrogen 2.959 N/A SER 400.A N GLU 396.A O no hydrogen 3.253 N/A SER 400.A OG GLU 396.A O no hydrogen 3.173 N/A ILE 401.A N ASN 398.A O no hydrogen 3.334 N/A LYS 402.A N LYS 397.A O no hydrogen 2.954 N/A