Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6es0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 9.A N ILE 80.A O no hydrogen 2.808 N/A TYR 11.A N GLU 83.A OE1 no hydrogen 3.048 N/A LYS 13.A N PRO 10.A O no hydrogen 3.188 N/A LYS 13.A NZ ASP 35.A OD2 no hydrogen 3.479 N/A LEU 14.A N TYR 11.A O no hydrogen 3.176 N/A ALA 15.A N ARG 32.A O no hydrogen 2.727 N/A ARG 18.A N SER 30.A O no hydrogen 3.071 N/A LEU 20.A N VAL 28.A O no hydrogen 2.985 N/A ARG 22.A NH1 GLU 101.A OE2 no hydrogen 2.452 N/A ARG 22.A NH2 GLU 101.A OE1 no hydrogen 3.488 N/A THR 27.A N ALA 24.A O no hydrogen 3.115 N/A THR 27.A OG1 ALA 24.A O no hydrogen 2.513 N/A SER 29.A N VAL 42.A O no hydrogen 2.749 N/A SER 29.A OG HIS 44.A NE2 no hydrogen 2.964 N/A SER 30.A N ARG 18.A O no hydrogen 2.949 N/A ALA 31.A N VAL 40.A O no hydrogen 3.102 N/A ARG 32.A N ALA 15.A O no hydrogen 2.812 N/A ARG 32.A NH1 ARG 37.A O no hydrogen 3.549 N/A HIS 33.A N VAL 38.A O no hydrogen 3.109 N/A ALA 34.A N LYS 13.A O no hydrogen 2.905 N/A ASP 35.A N HIS 33.A ND1 no hydrogen 3.216 N/A TRP 36.A N HIS 33.A ND1 no hydrogen 3.241 N/A ARG 37.A N HIS 33.A O no hydrogen 2.952 N/A ARG 37.A NH1 ALA 34.A O no hydrogen 3.076 N/A VAL 40.A N ALA 31.A O no hydrogen 3.020 N/A ALA 41.A N THR 91.A O no hydrogen 3.015 N/A VAL 42.A N SER 29.A O no hydrogen 2.671 N/A LYS 43.A N ILE 89.A O no hydrogen 2.810 N/A LYS 43.A NZ GLU 62.A OE2 no hydrogen 2.782 N/A LYS 43.A NZ ASP 160.A O no hydrogen 2.705 N/A LYS 43.A NZ GLY 162.A O no hydrogen 2.778 N/A HIS 44.A N THR 27.A O no hydrogen 2.804 N/A HIS 44.A ND1 LEU 45.A O no hydrogen 2.636 N/A HIS 44.A NE2 SER 29.A OG no hydrogen 2.964 N/A HIS 48.A NE2 GLU 55.A OE1 no hydrogen 3.009 N/A LEU 52.A N GLU 55.A OE1 no hydrogen 2.821 N/A GLU 55.A N LEU 52.A O no hydrogen 3.121 N/A ARG 56.A N LEU 52.A O no hydrogen 3.126 N/A ARG 56.A NH1 GLU 83.A O no hydrogen 3.280 N/A ARG 56.A NH2 ASN 82.A OD1 no hydrogen 2.718 N/A ARG 56.A NH2 GLU 83.A O no hydrogen 2.859 N/A LYS 57.A N ASP 53.A O no hydrogen 3.296 N/A VAL 59.A N GLU 55.A O no hydrogen 3.324 N/A VAL 59.A N ARG 56.A O no hydrogen 3.036 N/A LEU 60.A N ARG 56.A O no hydrogen 2.973 N/A ARG 61.A N LYS 57.A O no hydrogen 2.989 N/A GLU 62.A N ASP 58.A O no hydrogen 3.462 N/A ALA 63.A N VAL 59.A O no hydrogen 2.999 N/A GLU 64.A N LEU 60.A O no hydrogen 2.788 N/A ILE 65.A N ARG 61.A O no hydrogen 3.104 N/A LEU 66.A N GLU 62.A O no hydrogen 2.979 N/A HIS 67.A N ALA 63.A O no hydrogen 2.851 N/A LYS 68.A N GLU 64.A O no hydrogen 2.990 N/A ALA 69.A N ILE 65.A O no hydrogen 3.077 N/A ARG 70.A NH2 ILE 77.A O no hydrogen 2.776 N/A ILE 74.A N PHE 71.A O no hydrogen 3.220 N/A LEU 75.A N ILE 158.A O no hydrogen 3.160 N/A LEU 78.A N VAL 90.A O no hydrogen 2.844 N/A GLY 79.A N VAL 90.A O no hydrogen 3.244 N/A ILE 80.A N PRO 7.A O no hydrogen 3.063 N/A CYS 81.A N GLY 88.A O no hydrogen 2.919 N/A CYS 81.A SG ILE 9.A O no hydrogen 3.578 N/A GLU 83.A N PHE 86.A O no hydrogen 3.036 N/A GLY 88.A N CYS 81.A O no hydrogen 2.930 N/A ILE 89.A N LYS 43.A O no hydrogen 2.784 N/A VAL 90.A N GLY 79.A O no hydrogen 3.069 N/A THR 91.A N ALA 41.A O no hydrogen 2.906 N/A THR 91.A OG1 GLU 92.A O no hydrogen 2.956 N/A GLU 92.A N PRO 76.A O no hydrogen 3.058 N/A ASN 96.A N LEU 150.A O no hydrogen 3.370 N/A ASN 96.A ND2 ASP 151.A O no hydrogen 2.714 N/A ASN 96.A ND2 ASN 152.A O no hydrogen 3.583 N/A SER 98.A N GLU 101.A OE1 no hydrogen 3.433 N/A LEU 99.A N ILE 148.A O no hydrogen 2.803 N/A ASN 100.A N THR 145.A O no hydrogen 3.220 N/A GLU 101.A N SER 98.A O no hydrogen 3.026 N/A LEU 102.A N SER 98.A O no hydrogen 3.428 N/A LEU 103.A N LEU 99.A O no hydrogen 3.219 N/A HIS 104.A N ASN 100.A O no hydrogen 3.470 N/A HIS 104.A NE2 GLU 193.A OE2 no hydrogen 2.801 N/A ARG 105.A N GLU 101.A O no hydrogen 3.112 N/A LYS 106.A NZ ARG 197.A O no hydrogen 3.025 N/A TYR 109.A N ARG 105.A O no hydrogen 3.019 N/A ARG 117.A N ALA 113.A O no hydrogen 3.355 N/A ARG 117.A NE VAL 112.A O no hydrogen 3.053 N/A ARG 117.A NH1 VAL 194.A O no hydrogen 3.026 N/A ARG 117.A NH2 VAL 112.A O no hydrogen 3.108 N/A PHE 118.A N TRP 114.A O no hydrogen 2.990 N/A ARG 119.A N PRO 115.A O no hydrogen 3.046 N/A ARG 119.A NH2 GLU 153.A O no hydrogen 2.967 N/A ARG 119.A NH2 PHE 154.A O no hydrogen 3.224 N/A ILE 120.A N LEU 116.A O no hydrogen 2.922 N/A LEU 121.A N ARG 117.A O no hydrogen 3.077 N/A HIS 122.A N PHE 118.A O no hydrogen 3.013 N/A GLU 123.A N ARG 119.A O no hydrogen 2.914 N/A ILE 124.A N ILE 120.A O no hydrogen 2.992 N/A ALA 125.A N LEU 121.A O no hydrogen 3.282 N/A LEU 126.A N HIS 122.A O no hydrogen 3.068 N/A GLY 127.A N GLU 123.A O no hydrogen 3.127 N/A VAL 128.A N ILE 124.A O no hydrogen 3.232 N/A ASN 129.A N ALA 125.A O no hydrogen 2.919 N/A TYR 130.A N LEU 126.A O no hydrogen 3.188 N/A LEU 131.A N GLY 127.A O no hydrogen 3.291 N/A HIS 132.A N VAL 128.A O no hydrogen 3.004 N/A HIS 132.A NE2 ASP 183.A OD2 no hydrogen 2.934 N/A ASN 133.A N ASN 129.A O no hydrogen 3.168 N/A ASN 133.A ND2 ASN 129.A O no hydrogen 2.439 N/A ASN 133.A ND2 ASN 129.A OD1 no hydrogen 3.183 N/A MET 134.A N LEU 131.A O no hydrogen 3.454 N/A LEU 138.A N LEU 131.A O no hydrogen 2.836 N/A HIS 140.A N ASP 183.A OD2 no hydrogen 3.069 N/A HIS 140.A NE2 ALA 159.A O no hydrogen 3.139 N/A HIS 141.A N ASP 183.A OD1 no hydrogen 2.765 N/A ASP 142.A N HIS 140.A ND1 no hydrogen 2.969 N/A THR 145.A OG1 GLN 146.A OE1 no hydrogen 3.208 N/A GLN 146.A N GLN 146.A OE1 no hydrogen 3.029 N/A ASN 147.A N LYS 144.A O no hydrogen 3.017 N/A ASN 147.A ND2 ASP 142.A O no hydrogen 2.723 N/A ILE 148.A N THR 145.A O no hydrogen 3.370 N/A LEU 149.A N LYS 157.A O no hydrogen 2.837 N/A LEU 150.A N GLY 97.A O no hydrogen 2.962 N/A ASP 151.A N HIS 155.A O no hydrogen 3.149 N/A GLU 153.A N ASP 151.A OD1 no hydrogen 3.005 N/A PHE 154.A N ASP 151.A O no hydrogen 3.165 N/A HIS 155.A N ASP 151.A OD1 no hydrogen 2.684 N/A HIS 155.A ND1 GLU 123.A OE1 no hydrogen 2.829 N/A VAL 156.A N GLU 123.A OE2 no hydrogen 2.887 N/A LYS 157.A N LEU 149.A O no hydrogen 2.914 N/A LYS 157.A NZ SER 72.A O no hydrogen 3.381 N/A ILE 158.A N TYR 73.A O no hydrogen 3.132 N/A ALA 159.A N ASN 147.A O no hydrogen 2.955 N/A PHE 161.A N ASN 147.A OD1 no hydrogen 3.256 N/A GLY 162.A N ASP 160.A OD1 no hydrogen 2.877 N/A LYS 165.A NZ ASP 142.A OD1 no hydrogen 2.929 N/A TRP 166.A N LEU 163.A O no hydrogen 3.507 N/A TYR 171.A OH GLU 193.A OE1 no hydrogen 2.573 N/A MET 172.A N ILE 169.A O no hydrogen 3.358 N/A GLU 175.A N GLU 175.A OE1 no hydrogen 2.916 N/A ASN 176.A N PRO 173.A O no hydrogen 3.208 N/A TYR 177.A N PRO 174.A O no hydrogen 3.208 N/A SER 179.A OG HIS 141.A NE2 no hydrogen 3.292 N/A SER 179.A OG ALA 178.A O no hydrogen 2.403 N/A SER 179.A OG SER 179.A O no hydrogen 2.574 N/A LYS 181.A NZ ARG 252.A O no hydrogen 2.711 N/A TYR 185.A N HIS 182.A O no hydrogen 3.199 N/A SER 186.A N HIS 182.A O no hydrogen 3.353 N/A SER 186.A OG TYR 171.A O no hydrogen 2.668 N/A SER 186.A OG HIS 182.A O no hydrogen 3.525 N/A TYR 187.A N ASP 183.A O no hydrogen 2.954 N/A TYR 187.A OH LEU 121.A O no hydrogen 2.740 N/A ALA 188.A N ILE 184.A O no hydrogen 3.094 N/A VAL 189.A N TYR 185.A O no hydrogen 3.378 N/A ILE 190.A N SER 186.A O no hydrogen 3.057 N/A THR 191.A N TYR 187.A O no hydrogen 2.888 N/A THR 191.A OG1 TYR 187.A O no hydrogen 2.803 N/A TRP 192.A N ALA 188.A O no hydrogen 3.133 N/A TRP 192.A NE1 VAL 221.A O no hydrogen 2.943 N/A GLU 193.A N VAL 189.A O no hydrogen 2.857 N/A VAL 194.A N ILE 190.A O no hydrogen 2.820 N/A LEU 195.A N THR 191.A O no hydrogen 3.046 N/A SER 196.A OG TRP 192.A O no hydrogen 2.638 N/A SER 196.A OG GLU 193.A O no hydrogen 3.546 N/A ARG 197.A N GLU 193.A O no hydrogen 2.856 N/A ARG 197.A NE LEU 103.A O no hydrogen 2.781 N/A ARG 197.A NH1 TYR 109.A O no hydrogen 3.402 N/A ARG 197.A NH1 PRO 110.A O no hydrogen 3.353 N/A ARG 197.A NH2 LEU 103.A O no hydrogen 2.949 N/A ARG 197.A NH2 TYR 109.A O no hydrogen 3.012 N/A LYS 198.A N SER 196.A OG no hydrogen 3.296 N/A GLN 209.A N ASN 206.A O no hydrogen 3.136 N/A MET 211.A N PRO 207.A O no hydrogen 2.930 N/A TYR 212.A N LEU 208.A O no hydrogen 3.003 N/A SER 213.A N GLN 209.A O no hydrogen 3.010 N/A SER 213.A OG GLN 209.A O no hydrogen 2.665 N/A VAL 214.A N ILE 210.A O no hydrogen 2.946 N/A SER 215.A N MET 211.A O no hydrogen 3.176 N/A SER 215.A OG MET 211.A O no hydrogen 3.434 N/A SER 215.A OG TYR 212.A O no hydrogen 2.468 N/A GLN 216.A N TYR 212.A O no hydrogen 3.237 N/A GLN 216.A N SER 213.A O no hydrogen 3.058 N/A GLY 217.A N VAL 214.A O no hydrogen 3.125 N/A HIS 218.A N SER 213.A O no hydrogen 2.859 N/A ARG 219.A NE TRP 245.A O no hydrogen 2.962 N/A ARG 219.A NH1 VAL 214.A O no hydrogen 3.113 N/A ARG 219.A NH1 HIS 218.A O no hydrogen 2.913 N/A ARG 219.A NH2 TRP 245.A O no hydrogen 3.244 N/A ARG 219.A NH2 GLN 247.A OE1 no hydrogen 2.825 N/A ASN 223.A N SER 226.A OG no hydrogen 2.886 N/A SER 226.A N ASN 223.A OD1 no hydrogen 2.937 N/A SER 226.A OG VAL 221.A O no hydrogen 2.997 N/A SER 226.A OG ASN 223.A O no hydrogen 3.065 N/A SER 226.A OG ASN 223.A OD1 no hydrogen 3.177 N/A LEU 227.A N ASN 223.A O no hydrogen 2.865 N/A HIS 233.A NE2 THR 268.A OG1 no hydrogen 3.182 N/A ARG 234.A NE LEU 227.A O no hydrogen 3.198 N/A ARG 234.A NE PRO 228.A O no hydrogen 3.394 N/A ARG 234.A NH2 LEU 227.A O no hydrogen 3.198 N/A MET 237.A N HIS 233.A O no hydrogen 3.022 N/A ILE 238.A N ARG 234.A O no hydrogen 3.145 N/A SER 239.A N ALA 235.A O no hydrogen 3.248 N/A SER 239.A OG ALA 235.A O no hydrogen 2.980 N/A LEU 240.A N ARG 236.A O no hydrogen 3.229 N/A ILE 241.A N MET 237.A O no hydrogen 3.006 N/A GLU 242.A N ILE 238.A O no hydrogen 2.952 N/A SER 243.A N SER 239.A O no hydrogen 3.112 N/A SER 243.A OG SER 239.A O no hydrogen 2.628 N/A SER 243.A OG LEU 240.A O no hydrogen 3.052 N/A GLY 244.A N LEU 240.A O no hydrogen 2.812 N/A TRP 245.A N ILE 241.A O no hydrogen 2.970 N/A GLN 247.A NE2 SER 215.A O no hydrogen 3.173 N/A ASP 250.A N ASN 248.A OD1 no hydrogen 3.421 N/A GLU 251.A N ASN 248.A O no hydrogen 3.193 N/A ARG 252.A N PRO 249.A O no hydrogen 3.374 N/A ARG 252.A NE ALA 246.A O no hydrogen 2.702 N/A ARG 252.A NH1 GLU 175.A OE2 no hydrogen 2.833 N/A ARG 252.A NH1 LYS 181.A O no hydrogen 3.050 N/A ARG 252.A NH2 GLU 175.A OE1 no hydrogen 2.928 N/A ARG 252.A NH2 ALA 246.A O no hydrogen 2.770 N/A LYS 257.A N SER 254.A OG no hydrogen 3.334 N/A CYS 258.A N SER 254.A O no hydrogen 3.256 N/A CYS 258.A SG SER 254.A O no hydrogen 3.401 N/A LEU 259.A N PHE 255.A O no hydrogen 3.070 N/A ILE 260.A N LEU 256.A O no hydrogen 3.030 N/A GLU 261.A N LYS 257.A O no hydrogen 3.231 N/A LEU 262.A N CYS 258.A O no hydrogen 2.780 N/A GLU 263.A N LEU 259.A O no hydrogen 3.057 N/A LEU 266.A N LEU 262.A O no hydrogen 3.013 N/A ARG 267.A N GLU 263.A O no hydrogen 3.252 N/A THR 268.A N VAL 265.A O no hydrogen 3.187 N/A THR 268.A OG1 HIS 233.A NE2 no hydrogen 3.182 N/A THR 268.A OG1 VAL 265.A O no hydrogen 2.731 N/A PHE 269.A N LEU 266.A O no hydrogen 3.224 N/A THR 273.A OG1 GLU 270.A O no hydrogen 2.551 N/A PHE 274.A N GLU 271.A O no hydrogen 3.432 N/A GLU 276.A N ILE 272.A O no hydrogen 3.118 N/A ALA 277.A N THR 273.A O no hydrogen 3.107 N/A VAL 278.A N PHE 274.A O no hydrogen 3.198 N/A ILE 279.A N LEU 275.A O no hydrogen 2.932 N/A GLN 280.A N GLU 276.A O no hydrogen 3.281 N/A LEU 281.A N ALA 277.A O no hydrogen 3.452 N/A LYS 282.A N VAL 278.A O no hydrogen 3.311 N/A LYS 282.A NZ ASN 152.A O no hydrogen 3.509 N/A LYS 283.A N ILE 279.A O no hydrogen 3.185 N/A THR 284.A N GLN 280.A O no hydrogen 2.863 N/A THR 284.A OG1 GLU 108.A O no hydrogen 3.539 N/A THR 284.A OG1 LEU 281.A O no hydrogen 2.881 N/A LYS 285.A N LEU 281.A O no hydrogen 2.931 N/A LEU 286.A N LYS 283.A O no hydrogen 3.025 N/A SER 288.A N LYS 285.A O no hydrogen 3.494 N/A