Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6f7b_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N GLY 221.A O no hydrogen 3.202 N/A VAL 6.A N ILE 223.A O no hydrogen 2.975 N/A TRP 10.A N ASN 8.A OD1 no hydrogen 2.910 N/A TRP 10.A NE1 GLN 211.A O no hydrogen 2.905 N/A ASP 11.A N ASN 8.A O no hydrogen 3.318 N/A ILE 15.A N ASP 11.A O no hydrogen 3.051 N/A PHE 16.A N ASP 12.A O no hydrogen 3.086 N/A LYS 17.A N LYS 13.A O no hydrogen 2.878 N/A LEU 18.A N LEU 14.A O no hydrogen 2.815 N/A LEU 19.A N ILE 15.A O no hydrogen 2.927 N/A SER 20.A N PHE 16.A O no hydrogen 3.051 N/A SER 20.A OG PHE 16.A O no hydrogen 2.734 N/A GLY 21.A N LYS 17.A O no hydrogen 3.076 N/A SER 28.A N PRO 25.A O no hydrogen 3.038 N/A SER 28.A OG PRO 25.A O no hydrogen 2.684 N/A TYR 29.A N VAL 26.A O no hydrogen 3.086 N/A THR 32.A N TYR 29.A O no hydrogen 3.221 N/A THR 32.A OG1 VAL 26.A O no hydrogen 2.671 N/A PHE 33.A N ALA 117.A O no hydrogen 2.914 N/A TRP 35.A N LEU 119.A O no hydrogen 2.847 N/A TRP 35.A NE1 HIS 118.A ND1 no hydrogen 3.125 N/A CYS 37.A SG LYS 38.A O no hydrogen 3.590 N/A LEU 39.A N ASN 122.A OD1 no hydrogen 2.573 N/A LYS 45.A N VAL 57.A O no hydrogen 2.661 N/A THR 46.A OG1 LYS 43.A O no hydrogen 2.612 N/A PHE 48.A N VAL 55.A O no hydrogen 2.910 N/A GLN 49.A NE2 SER 52.A O no hydrogen 3.358 N/A LEU 50.A N LYS 53.A O no hydrogen 2.852 N/A VAL 55.A N PHE 48.A O no hydrogen 2.735 N/A TYR 56.A N THR 73.A O no hydrogen 3.010 N/A VAL 57.A N THR 46.A O no hydrogen 3.060 N/A HIS 58.A N GLU 71.A O no hydrogen 2.841 N/A HIS 58.A NE2 THR 73.A OG1 no hydrogen 3.257 N/A LEU 61.A N VAL 69.A O no hydrogen 2.682 N/A GLY 62.A N VAL 69.A O no hydrogen 3.216 N/A GLY 64.A N ALA 67.A O no hydrogen 2.937 N/A ALA 67.A N GLY 64.A O no hydrogen 2.941 N/A GLN 68.A N VAL 84.A O no hydrogen 2.941 N/A GLN 68.A NE2 GLU 63.A OE1 no hydrogen 3.059 N/A VAL 69.A N GLY 62.A O no hydrogen 2.746 N/A TYR 70.A N LEU 82.A O no hydrogen 2.839 N/A TYR 70.A OH GLN 68.A OE1 no hydrogen 2.745 N/A GLU 71.A N HIS 59.A O no hydrogen 3.029 N/A ALA 72.A N PHE 80.A O no hydrogen 2.768 N/A THR 73.A N TYR 56.A O no hydrogen 3.049 N/A THR 73.A OG1 HIS 58.A NE2 no hydrogen 3.257 N/A PHE 80.A N ALA 72.A O no hydrogen 2.710 N/A VAL 81.A N GLY 128.A O no hydrogen 2.929 N/A LEU 82.A N TYR 70.A O no hydrogen 2.873 N/A LYS 83.A N LEU 126.A O no hydrogen 2.817 N/A LYS 83.A NZ GLU 92.A OE1 no hydrogen 3.244 N/A LYS 83.A NZ GLU 92.A OE2 no hydrogen 2.854 N/A VAL 84.A N GLN 68.A O no hydrogen 2.781 N/A GLN 85.A N SER 124.A O no hydrogen 2.850 N/A GLN 85.A NE2 GLU 92.A OE1 no hydrogen 2.668 N/A LYS 86.A N PHE 66.A O no hydrogen 3.032 N/A ASN 89.A N SER 124.A OG no hydrogen 3.089 N/A TRP 91.A NE1 SER 212.A O no hydrogen 2.858 N/A GLU 92.A N ASN 89.A OD1 no hydrogen 3.052 N/A TYR 94.A N PRO 90.A O no hydrogen 2.831 N/A TYR 94.A OH ASP 214.A OD2 no hydrogen 2.589 N/A ILE 95.A N TRP 91.A O no hydrogen 2.963 N/A GLY 96.A N GLU 92.A O no hydrogen 2.915 N/A THR 97.A N PHE 93.A O no hydrogen 2.922 N/A THR 97.A OG1 PHE 93.A O no hydrogen 2.814 N/A GLN 98.A N TYR 94.A O no hydrogen 3.010 N/A LEU 99.A N ILE 95.A O no hydrogen 2.798 N/A MET 100.A N GLY 96.A O no hydrogen 3.140 N/A GLU 101.A N THR 97.A O no hydrogen 3.037 N/A ARG 102.A N GLN 98.A O no hydrogen 2.908 N/A ARG 102.A N LEU 99.A O no hydrogen 3.104 N/A ARG 102.A NH1 GLN 98.A OE1 no hydrogen 3.313 N/A ARG 102.A NH1 ASP 214.A OD1 no hydrogen 3.391 N/A ARG 102.A NH1 ASP 214.A OD2 no hydrogen 2.852 N/A ARG 102.A NH2 CYS 173.A O no hydrogen 2.930 N/A ARG 102.A NH2 ASP 214.A OD1 no hydrogen 2.809 N/A LEU 103.A N LEU 99.A O no hydrogen 2.888 N/A MET 107.A N LYS 104.A O no hydrogen 2.917 N/A GLN 108.A N PRO 105.A O no hydrogen 3.319 N/A GLN 108.A NE2 LEU 103.A O no hydrogen 3.541 N/A MET 110.A N MET 107.A O no hydrogen 3.078 N/A PHE 111.A N GLN 108.A O no hydrogen 3.079 N/A LYS 113.A N GLU 129.A OE2 no hydrogen 2.979 N/A TYR 115.A N VAL 127.A O no hydrogen 2.823 N/A SER 116.A OG HIS 118.A NE2 no hydrogen 3.079 N/A ALA 117.A N ASN 31.A O.A no hydrogen 3.072 N/A ALA 117.A N ASN 31.A O.B no hydrogen 3.093 N/A HIS 118.A N VAL 125.A O no hydrogen 2.833 N/A HIS 118.A NE2 SER 116.A OG no hydrogen 3.079 N/A LEU 119.A N PHE 33.A O no hydrogen 2.711 N/A PHE 120.A N GLY 123.A O no hydrogen 2.828 N/A GLN 121.A N CYS 37.A O no hydrogen 3.134 N/A SER 124.A N GLN 85.A O no hydrogen 2.895 N/A VAL 125.A N HIS 118.A O no hydrogen 2.962 N/A LEU 126.A N LYS 83.A O no hydrogen 2.860 N/A VAL 127.A N SER 116.A O no hydrogen 2.954 N/A GLY 128.A N VAL 81.A O no hydrogen 2.798 N/A GLU 129.A N LYS 113.A O no hydrogen 2.926 N/A TYR 133.A N LEU 187.A O no hydrogen 2.903 N/A TYR 133.A OH ASN 189.A OD1 no hydrogen 3.075 N/A THR 135.A OG1 ASP 183.A OD1.B no hydrogen 3.072 N/A LEU 136.A N PHE 185.A O no hydrogen 2.868 N/A LEU 137.A N PRO 182.A O no hydrogen 3.125 N/A ASN 138.A N THR 135.A OG1 no hydrogen 2.972 N/A ALA 139.A N THR 135.A O no hydrogen 3.110 N/A ILE 140.A N LEU 136.A O no hydrogen 2.962 N/A ASN 141.A N LEU 137.A O no hydrogen 3.046 N/A LEU 142.A N ASN 138.A O no hydrogen 2.877 N/A TYR 143.A N ALA 139.A O no hydrogen 3.285 N/A TYR 143.A N ILE 140.A O no hydrogen 3.226 N/A LYS 144.A N ASN 141.A O no hydrogen 3.135 N/A LYS 144.A NZ ASN 141.A OD1 no hydrogen 2.836 N/A LYS 144.A NZ GLY 262.A O no hydrogen 2.677 N/A THR 146.A N TYR 143.A O no hydrogen 3.181 N/A THR 146.A OG1 TYR 143.A O no hydrogen 2.871 N/A LYS 149.A N THR 146.A O no hydrogen 3.233 N/A LYS 149.A N THR 146.A OG1 no hydrogen 3.275 N/A LEU 155.A N PRO 152.A O no hydrogen 3.077 N/A VAL 156.A N PRO 152.A O no hydrogen 3.072 N/A ILE 157.A N GLN 153.A O no hydrogen 2.831 N/A SER 158.A N GLY 154.A O no hydrogen 3.071 N/A SER 158.A OG ASP 199.A O no hydrogen 2.672 N/A SER 158.A OG SER 201.A OG no hydrogen 2.875 N/A PHE 159.A N LEU 155.A O no hydrogen 2.840 N/A ALA 160.A N VAL 156.A O no hydrogen 2.831 N/A MET 161.A N ILE 157.A O no hydrogen 2.894 N/A ARG 162.A N.A SER 158.A O no hydrogen 3.104 N/A ARG 162.A N.B SER 158.A O no hydrogen 3.113 N/A ARG 162.A NE.A SER 201.A O no hydrogen 2.766 N/A ARG 162.A NE.B SER 201.A O no hydrogen 3.022 N/A MET 163.A N PHE 159.A O no hydrogen 2.910 N/A LEU 164.A N ALA 160.A O no hydrogen 3.024 N/A TYR 165.A N MET 161.A O no hydrogen 3.072 N/A MET 166.A N ARG 162.A O.A no hydrogen 2.877 N/A MET 166.A N ARG 162.A O.B no hydrogen 2.853 N/A ILE 167.A N MET 163.A O no hydrogen 2.894 N/A GLU 168.A N LEU 164.A O no hydrogen 2.960 N/A GLN 169.A N TYR 165.A O no hydrogen 3.226 N/A GLN 169.A NE2 TYR 165.A O no hydrogen 3.491 N/A VAL 170.A N MET 166.A O no hydrogen 3.016 N/A HIS 171.A N ILE 167.A O no hydrogen 2.766 N/A HIS 171.A NE2 ASP 248.A OD2 no hydrogen 2.820 N/A ASP 172.A N GLU 168.A O no hydrogen 2.920 N/A CYS 173.A N GLN 169.A O no hydrogen 3.132 N/A CYS 173.A SG GLN 169.A O no hydrogen 3.371 N/A GLU 174.A N HIS 171.A O no hydrogen 2.827 N/A ILE 175.A N VAL 170.A O no hydrogen 3.275 N/A ILE 176.A N ILE 213.A O no hydrogen 2.919 N/A HIS 177.A N ASP 248.A OD2 no hydrogen 2.799 N/A HIS 177.A NE2 ILE 207.A O no hydrogen 2.918 N/A GLY 178.A N ASP 248.A OD1 no hydrogen 2.886 N/A ASP 179.A N HIS 177.A ND1 no hydrogen 2.985 N/A LYS 181.A NZ ASP 179.A OD1 no hydrogen 3.120 N/A LYS 181.A NZ ASP 179.A OD2 no hydrogen 2.863 N/A ASN 184.A N LYS 181.A O no hydrogen 3.025 N/A ASN 184.A ND2 ASP 179.A O no hydrogen 2.862 N/A ASN 184.A ND2 ASP 179.A OD2 no hydrogen 3.230 N/A PHE 185.A N PRO 182.A O no hydrogen 3.293 N/A ILE 186.A N ALA 205.A O no hydrogen 2.926 N/A LEU 187.A N GLY 134.A O no hydrogen 2.889 N/A GLY 188.A N GLY 203.A O no hydrogen 2.883 N/A PHE 191.A N GLY 188.A O no hydrogen 3.001 N/A GLU 193.A N ASN 189.A O no hydrogen 2.719 N/A GLN 194.A N PHE 191.A O no hydrogen 3.257 N/A GLN 194.A NE2 ASP 196.A OD1 no hydrogen 3.189 N/A GLN 194.A NE2 LEU 200.A O no hydrogen 3.263 N/A ASP 198.A N.A ASP 196.A OD1 no hydrogen 3.142 N/A ASP 198.A N.B ASP 196.A OD1 no hydrogen 3.135 N/A SER 201.A OG SER 158.A OG no hydrogen 2.875 N/A ALA 202.A N GLN 194.A OE1 no hydrogen 2.879 N/A ALA 205.A N ILE 186.A O no hydrogen 3.062 N/A ILE 207.A N ASN 184.A O no hydrogen 2.864 N/A LEU 209.A N GLU 92.A OE2 no hydrogen 2.789 N/A GLY 210.A N ASP 208.A OD1 no hydrogen 3.086 N/A GLN 211.A NE2 GLU 229.A OE2 no hydrogen 2.873 N/A SER 212.A N LEU 209.A O no hydrogen 3.009 N/A SER 212.A OG HIS 177.A O no hydrogen 2.854 N/A ILE 213.A N ILE 176.A O no hydrogen 2.884 N/A MET 215.A N GLU 174.A O no hydrogen 2.799 N/A LYS 216.A N ASP 214.A OD1 no hydrogen 2.904 N/A LEU 217.A N ASP 214.A O no hydrogen 3.154 N/A PHE 218.A N MET 215.A O no hydrogen 3.300 N/A THR 222.A N PRO 219.A O no hydrogen 3.174 N/A THR 222.A OG1 PRO 219.A O no hydrogen 2.526 N/A ILE 223.A N PHE 4.A O no hydrogen 2.995 N/A PHE 224.A N TRP 243.A O no hydrogen 2.746 N/A THR 225.A N GLY 7.A O no hydrogen 3.199 N/A THR 225.A OG1 GLY 7.A O no hydrogen 3.305 N/A ALA 226.A N GLY 7.A O no hydrogen 2.807 N/A LYS 227.A NZ MET 237.A O no hydrogen 2.747 N/A LYS 227.A NZ ASN 240.A OD1 no hydrogen 2.798 N/A CYS 228.A SG GLU 229.A O no hydrogen 3.690 N/A CYS 234.A SG GLU 236.A OE2 no hydrogen 3.427 N/A GLU 236.A N GLU 236.A OE2 no hydrogen 2.754 N/A LEU 238.A N CYS 234.A O no hydrogen 2.993 N/A SER 239.A N VAL 235.A O no hydrogen 3.070 N/A SER 239.A N GLU 236.A O no hydrogen 3.229 N/A SER 239.A OG VAL 235.A O no hydrogen 2.973 N/A ASN 240.A N MET 237.A O no hydrogen 3.492 N/A LYS 241.A N GLU 236.A O no hydrogen 2.790 N/A TRP 243.A N PHE 224.A O no hydrogen 2.878 N/A TRP 243.A NE1 ALA 226.A O no hydrogen 2.931 N/A ASN 244.A N GLN 246.A OE1 no hydrogen 2.788 N/A ASN 244.A ND2 THR 222.A O no hydrogen 2.889 N/A TYR 245.A N ASN 244.A OD1 no hydrogen 2.647 N/A GLN 246.A N GLN 246.A OE1 no hydrogen 2.879 N/A ILE 247.A N ASN 244.A O no hydrogen 3.373 N/A ASP 248.A N TYR 245.A O no hydrogen 3.055 N/A TYR 249.A OH PRO 304.A O no hydrogen 2.871 N/A PHE 250.A N GLN 246.A O no hydrogen 3.018 N/A GLY 251.A N ILE 247.A O no hydrogen 3.066 N/A VAL 252.A N ASP 248.A O no hydrogen 2.894 N/A ALA 253.A N TYR 249.A O no hydrogen 3.012 N/A ALA 254.A N PHE 250.A O no hydrogen 2.850 N/A THR 255.A N GLY 251.A O no hydrogen 2.937 N/A THR 255.A OG1 GLY 251.A O no hydrogen 2.809 N/A VAL 256.A N VAL 252.A O no hydrogen 2.903 N/A TYR 257.A N ALA 253.A O no hydrogen 2.826 N/A TYR 257.A OH GLU 275.A O no hydrogen 2.747 N/A CYS 258.A N ALA 254.A O no hydrogen 3.032 N/A CYS 258.A SG THR 263.A O no hydrogen 3.779 N/A MET 259.A N THR 255.A O no hydrogen 3.049 N/A LEU 260.A N VAL 256.A O no hydrogen 2.916 N/A PHE 261.A N TYR 257.A O no hydrogen 2.974 N/A LYS 268.A N LYS 273.A O no hydrogen 2.776 N/A GLU 270.A N GLU 271.A O no hydrogen 2.685 N/A CYS 272.A N ASN 296.A OD1 no hydrogen 2.688 N/A LYS 273.A N LYS 268.A O no hydrogen 2.776 N/A LYS 273.A NZ GLU 270.A OE1 no hydrogen 3.535 N/A GLU 275.A N LYS 266.A O no hydrogen 2.934 N/A LEU 281.A N PHE 278.A O no hydrogen 3.218 N/A HIS 283.A NE2 TYR 321.A OH no hydrogen 2.648 N/A TRP 287.A N HIS 283.A O no hydrogen 2.962 N/A TRP 287.A NE1 GLN 153.A OE1 no hydrogen 2.867 N/A ASN 288.A N LEU 284.A O no hydrogen 2.884 N/A GLU 289.A N ASP 285.A O no hydrogen 3.104 N/A PHE 290.A N MET 286.A O no hydrogen 2.799 N/A PHE 291.A N TRP 287.A O no hydrogen 2.934 N/A HIS 292.A N ASN 288.A O no hydrogen 2.861 N/A HIS 292.A ND1 GLU 271.A OE2 no hydrogen 2.960 N/A VAL 293.A N GLU 289.A O no hydrogen 3.014 N/A MET 294.A N PHE 290.A O no hydrogen 2.990 N/A LEU 295.A N PHE 291.A O no hydrogen 3.009 N/A ASN 296.A ND2 CYS 272.A O no hydrogen 2.944 N/A ASN 296.A ND2 HIS 292.A O no hydrogen 2.967 N/A CYS 300.A SG GLN 246.A OE1 no hydrogen 3.785 N/A HIS 301.A N ASP 299.A OD1 no hydrogen 2.764 N/A HIS 302.A N ASP 299.A O no hydrogen 3.148 N/A HIS 302.A ND1 ASP 299.A OD1 no hydrogen 2.809 N/A LEU 308.A N SER 305.A OG no hydrogen 3.120 N/A LEU 309.A N SER 305.A O no hydrogen 3.041 N/A ARG 310.A N LEU 306.A O no hydrogen 3.052 N/A GLN 311.A N ASP 307.A O no hydrogen 2.822 N/A LYS 312.A N LEU 308.A O no hydrogen 3.087 N/A LYS 312.A NZ GLU 289.A OE2 no hydrogen 3.116 N/A LEU 313.A N.A LEU 309.A O no hydrogen 3.425 N/A LEU 313.A N.B LEU 309.A O no hydrogen 3.438 N/A LYS 314.A N ARG 310.A O no hydrogen 2.833 N/A LYS 315.A N GLN 311.A O no hydrogen 3.125 N/A PHE 317.A N LEU 313.A O.A no hydrogen 2.907 N/A PHE 317.A N LEU 313.A O.B no hydrogen 2.889 N/A GLN 318.A N LYS 314.A O no hydrogen 2.805 N/A GLN 319.A N LYS 315.A O no hydrogen 3.193 N/A HIS 320.A N VAL 316.A O no hydrogen 2.978 N/A HIS 320.A ND1 VAL 316.A O no hydrogen 3.201 N/A TYR 321.A N PHE 317.A O no hydrogen 2.747 N/A TYR 321.A OH HIS 283.A NE2 no hydrogen 2.648 N/A THR 322.A OG1 GLN 318.A O no hydrogen 3.337 N/A LYS 324.A N TYR 321.A O no hydrogen 2.924 N/A ILE 325.A N TYR 321.A O no hydrogen 2.998 N/A LEU 328.A N LYS 324.A O no hydrogen 2.991 N/A ARG 329.A N ILE 325.A O no hydrogen 2.840 N/A ARG 329.A NE SER 201.A OG no hydrogen 3.022 N/A ARG 329.A NH1 SER 158.A OG no hydrogen 3.295 N/A ARG 329.A NH1 ASP 198.A O.A no hydrogen 2.776 N/A ARG 329.A NH1 ASP 198.A O.B no hydrogen 2.801 N/A ARG 329.A NH1 SER 201.A OG no hydrogen 3.174 N/A ARG 329.A NH2 ASP 198.A O.A no hydrogen 3.316 N/A ARG 329.A NH2 ASP 198.A O.B no hydrogen 3.330 N/A ASN 330.A N ARG 326.A O no hydrogen 2.885 N/A ARG 331.A N ALA 327.A O no hydrogen 3.024 N/A ARG 331.A NE GLU 148.A OE1 no hydrogen 2.727 N/A ARG 331.A NH2 GLU 148.A OE1 no hydrogen 2.719 N/A LEU 332.A N LEU 328.A O no hydrogen 3.202 N/A ILE 333.A N.A ARG 329.A O no hydrogen 2.829 N/A ILE 333.A N.B ARG 329.A O no hydrogen 2.828 N/A VAL 334.A N ASN 330.A O no hydrogen 3.001 N/A LEU 335.A N ARG 331.A O no hydrogen 3.090 N/A LEU 336.A N LEU 332.A O no hydrogen 2.679 N/A LEU 337.A N ILE 333.A O.A no hydrogen 2.755 N/A LEU 337.A N ILE 333.A O.B no hydrogen 2.879 N/A GLU 338.A N VAL 334.A O no hydrogen 3.153 N/A CYS 339.A N LEU 335.A O no hydrogen 3.059 N/A LYS 340.A N LEU 336.A O no hydrogen 3.153 N/A ARG 341.A N LEU 337.A O no hydrogen 3.187 N/A SER 342.A N CYS 339.A O no hydrogen 2.916 N/A