Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6fd3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N GLU 64.A OE1 no hydrogen 2.832 N/A MET 2.A N GLU 64.A OE1 no hydrogen 3.322 N/A THR 3.A N GLU 6.A OE1 no hydrogen 2.731 N/A GLU 6.A N THR 3.A OG1 no hydrogen 3.098 N/A ILE 7.A N THR 3.A O no hydrogen 2.902 N/A LEU 8.A N ASP 4.A O no hydrogen 2.952 N/A GLU 9.A N GLU 5.A O no hydrogen 2.805 N/A LYS 10.A N GLU 6.A O no hydrogen 2.992 N/A LEU 11.A N ILE 7.A O no hydrogen 2.916 N/A ARG 12.A N.A LEU 8.A O no hydrogen 2.920 N/A ARG 12.A N.B LEU 8.A O no hydrogen 2.931 N/A ARG 12.A NH2.B LEU 89.A O no hydrogen 3.234 N/A SER 13.A N GLU 9.A O no hydrogen 3.179 N/A SER 13.A OG LYS 10.A O no hydrogen 2.707 N/A ILE 14.A N LEU 11.A O no hydrogen 3.136 N/A VAL 15.A N LEU 11.A O no hydrogen 3.093 N/A SER 16.A N SER 87.A O no hydrogen 2.858 N/A SER 16.A OG ASP 86.A OD1 no hydrogen 2.526 N/A LYS 22.A N ASP 19.A O no hydrogen 3.212 N/A LYS 23.A N PRO 20.A O no hydrogen 3.008 N/A TYR 24.A N PRO 20.A O no hydrogen 3.145 N/A THR 25.A N LEU 42.A O no hydrogen 2.919 N/A GLU 28.A N THR 40.A O no hydrogen 2.928 N/A LYS 29.A NZ GLN 32.A OE1 no hydrogen 3.349 N/A ILE 30.A N VAL 38.A O no hydrogen 2.793 N/A GLY 31.A N VAL 38.A O no hydrogen 3.247 N/A GLY 33.A N GLY 36.A O no hydrogen 3.073 N/A SER 35.A OG.A GLN 60.A OE1 no hydrogen 2.552 N/A SER 35.A OG.B GLN 60.A OE1 no hydrogen 3.526 N/A THR 37.A N GLN 54.A O no hydrogen 2.942 N/A VAL 38.A N GLY 31.A O no hydrogen 2.864 N/A TYR 39.A N ILE 52.A O no hydrogen 2.858 N/A THR 40.A N GLU 28.A O no hydrogen 2.808 N/A THR 40.A OG1 GLU 28.A O no hydrogen 3.425 N/A ALA 41.A N VAL 50.A O no hydrogen 3.040 N/A LEU 42.A N THR 25.A O no hydrogen 2.821 N/A ASP 43.A N GLN 48.A O no hydrogen 2.901 N/A ILE 44.A N LYS 23.A O no hydrogen 2.911 N/A ALA 45.A N ASP 43.A OD2 no hydrogen 2.882 N/A THR 46.A N ASP 43.A OD2 no hydrogen 3.279 N/A GLY 47.A N ASP 43.A O no hydrogen 2.791 N/A GLN 48.A N THR 46.A OG1 no hydrogen 3.159 N/A VAL 50.A N ALA 41.A O no hydrogen 2.900 N/A ALA 51.A N MET 98.A O no hydrogen 2.931 N/A ILE 52.A N TYR 39.A O no hydrogen 2.755 N/A LYS 53.A N VAL 96.A O no hydrogen 2.831 N/A LYS 53.A NZ GLU 69.A OE2 no hydrogen 2.761 N/A GLN 54.A N THR 37.A O no hydrogen 2.779 N/A MET 55.A N LEU 94.A O no hydrogen 2.754 N/A LEU 57.A N ASP 92.A O no hydrogen 2.771 N/A GLN 58.A N ASN 56.A OD1 no hydrogen 3.333 N/A GLN 58.A NE2 ASP 4.A OD2 no hydrogen 2.676 N/A GLN 59.A N ASN 56.A O no hydrogen 3.254 N/A GLN 60.A NE2 SER 35.A O.A no hydrogen 3.055 N/A GLN 60.A NE2 SER 35.A O.B no hydrogen 2.915 N/A GLN 60.A NE2 ASN 56.A O no hydrogen 2.736 N/A LYS 63.A NZ GLN 58.A OE1 no hydrogen 2.758 N/A LEU 65.A N LYS 62.A O no hydrogen 3.321 N/A ILE 66.A N LYS 63.A O no hydrogen 3.224 N/A ILE 67.A N GLU 64.A O no hydrogen 3.240 N/A ASN 68.A ND2 CYS 165.A O.A no hydrogen 3.193 N/A ASN 68.A ND2 CYS 165.A O.B no hydrogen 3.542 N/A GLU 69.A N LEU 65.A O no hydrogen 3.241 N/A ILE 70.A N ILE 66.A O no hydrogen 3.346 N/A LEU 71.A N ILE 67.A O no hydrogen 3.079 N/A VAL 72.A N ASN 68.A O no hydrogen 2.695 N/A MET 73.A N.A GLU 69.A O no hydrogen 3.038 N/A MET 73.A N.B GLU 69.A O no hydrogen 3.041 N/A ARG 74.A N ILE 70.A O no hydrogen 3.088 N/A ARG 74.A NH2 ILE 14.A O no hydrogen 2.612 N/A GLU 75.A N LEU 71.A O no hydrogen 2.778 N/A ASN 76.A N VAL 72.A O no hydrogen 2.910 N/A LYS 77.A NZ ASN 83.A OD1 no hydrogen 2.672 N/A LYS 77.A NZ TYR 84.A O no hydrogen 2.840 N/A ASN 80.A N ASN 78.A OD1 no hydrogen 2.922 N/A ASN 80.A ND2 GLU 126.A OE1 no hydrogen 2.849 N/A ASN 80.A ND2 VAL 157.A O no hydrogen 2.914 N/A ILE 81.A N.A ASN 78.A O no hydrogen 2.946 N/A ILE 81.A N.B ASN 78.A O no hydrogen 2.963 N/A VAL 82.A N LEU 159.A O.A no hydrogen 2.974 N/A VAL 82.A N LEU 159.A O.B no hydrogen 2.958 N/A ASN 83.A N GLU 99.A OE2 no hydrogen 2.847 N/A TYR 84.A OH SER 87.A OG no hydrogen 2.830 N/A LEU 85.A N VAL 97.A O no hydrogen 2.889 N/A ASP 86.A N VAL 97.A O no hydrogen 3.162 N/A SER 87.A N ASP 86.A OD1 no hydrogen 2.930 N/A SER 87.A OG TYR 84.A OH no hydrogen 2.830 N/A TYR 88.A N TRP 95.A O no hydrogen 2.885 N/A VAL 90.A N GLU 93.A O no hydrogen 2.921 N/A GLU 93.A N VAL 90.A O no hydrogen 2.952 N/A LEU 94.A N MET 55.A O no hydrogen 2.745 N/A TRP 95.A N TYR 88.A O no hydrogen 2.872 N/A VAL 96.A N LYS 53.A O no hydrogen 2.875 N/A VAL 97.A N ASP 86.A O no hydrogen 2.754 N/A MET 98.A N ALA 51.A O no hydrogen 2.864 N/A GLU 99.A N ASN 83.A O no hydrogen 2.981 N/A GLY 104.A N LEU 101.A O no hydrogen 3.140 N/A SER 105.A N ASP 108.A OD2 no hydrogen 3.126 N/A LEU 106.A N ILE 149.A O no hydrogen 2.840 N/A THR 107.A OG1 SER 146.A OG no hydrogen 2.632 N/A THR 107.A OG1 ASP 147.A OD1.A no hydrogen 2.909 N/A ASP 108.A N SER 105.A O no hydrogen 3.024 N/A VAL 110.A N LEU 106.A O no hydrogen 2.924 N/A THR 111.A N THR 107.A O no hydrogen 3.046 N/A THR 111.A OG1 THR 107.A O no hydrogen 2.770 N/A THR 111.A OG1 ASP 108.A O no hydrogen 3.364 N/A GLU 112.A N VAL 109.A O no hydrogen 3.289 N/A THR 113.A N VAL 109.A O no hydrogen 2.917 N/A THR 113.A OG1 VAL 109.A O no hydrogen 2.786 N/A CYS 114.A SG.B MET 115.A O no hydrogen 3.823 N/A ASP 116.A N GLN 119.A OE1 no hydrogen 2.850 N/A GLN 119.A N ASP 116.A OD1 no hydrogen 2.845 N/A GLN 119.A NE2 SER 282.A O no hydrogen 2.956 N/A ILE 120.A N ASP 116.A O no hydrogen 2.933 N/A ALA 121.A N GLU 117.A O no hydrogen 2.847 N/A ALA 122.A N GLY 118.A O no hydrogen 3.060 N/A VAL 123.A N GLN 119.A O no hydrogen 3.094 N/A CYS 124.A N ILE 120.A O no hydrogen 2.846 N/A CYS 124.A SG ILE 120.A O no hydrogen 3.346 N/A ARG 125.A N ALA 121.A O no hydrogen 2.888 N/A ARG 125.A NE ASP 277.A OD2 no hydrogen 2.913 N/A ARG 125.A NH2 LEU 274.A O no hydrogen 3.218 N/A ARG 125.A NH2 ASP 277.A OD2 no hydrogen 3.534 N/A GLU 126.A N ALA 122.A O no hydrogen 3.184 N/A CYS 127.A N VAL 123.A O no hydrogen 2.976 N/A CYS 127.A SG VAL 123.A O no hydrogen 3.424 N/A LEU 128.A N CYS 124.A O no hydrogen 2.838 N/A GLN 129.A N ARG 125.A O no hydrogen 2.957 N/A ALA 130.A N GLU 126.A O no hydrogen 3.135 N/A LEU 131.A N CYS 127.A O no hydrogen 2.896 N/A ASP 132.A N LEU 128.A O no hydrogen 2.817 N/A PHE 133.A N GLN 129.A O no hydrogen 3.006 N/A LEU 134.A N ALA 130.A O no hydrogen 2.875 N/A HIS 135.A N LEU 131.A O no hydrogen 2.740 N/A HIS 135.A NE2 ASP 199.A OD2 no hydrogen 2.831 N/A SER 136.A N.A ASP 132.A O no hydrogen 2.938 N/A SER 136.A N.B ASP 132.A O no hydrogen 2.937 N/A SER 136.A OG.A ASP 132.A O no hydrogen 3.264 N/A SER 136.A OG.A PHE 133.A O no hydrogen 2.911 N/A SER 136.A OG.B ASP 132.A O no hydrogen 2.723 N/A ASN 137.A N PHE 133.A O no hydrogen 3.177 N/A ASN 137.A N LEU 134.A O no hydrogen 2.963 N/A ASN 137.A ND2 PHE 133.A O no hydrogen 2.860 N/A GLN 138.A N HIS 135.A O no hydrogen 2.927 N/A GLN 138.A NE2 ILE 168.A O no hydrogen 3.058 N/A VAL 139.A N LEU 134.A O no hydrogen 2.890 N/A ILE 140.A N ALA 166.A O no hydrogen 2.913 N/A HIS 141.A N ASP 199.A OD2 no hydrogen 2.814 N/A HIS 141.A NE2 THR 160.A O no hydrogen 2.922 N/A ARG 142.A N ASP 199.A OD1 no hydrogen 2.843 N/A ARG 142.A NE PHE 164.A O no hydrogen 2.754 N/A ARG 142.A NH1 TYR 194.A OH no hydrogen 2.893 N/A ARG 142.A NH2 PHE 164.A O no hydrogen 3.109 N/A ARG 142.A NH2 CYS 165.A O.B no hydrogen 3.113 N/A ASP 143.A N HIS 141.A ND1 no hydrogen 2.977 N/A LYS 145.A NZ THR 180.A OG1 no hydrogen 2.841 N/A SER 146.A N GLU 209.A OE1 no hydrogen 3.023 N/A SER 146.A OG THR 107.A OG1 no hydrogen 2.632 N/A SER 146.A OG GLU 209.A OE1 no hydrogen 3.482 N/A SER 146.A OG GLU 209.A OE2 no hydrogen 2.585 N/A ASN 148.A N LYS 145.A O no hydrogen 2.955 N/A ASN 148.A ND2 ASP 143.A O no hydrogen 2.770 N/A ASN 148.A ND2 ASP 143.A OD2 no hydrogen 3.102 N/A ILE 149.A N SER 146.A O no hydrogen 3.151 N/A LEU 150.A N LYS 158.A O no hydrogen 2.748 N/A LEU 151.A N GLY 104.A O no hydrogen 2.875 N/A GLY 152.A N SER 156.A O no hydrogen 2.871 N/A GLY 155.A N GLY 152.A O no hydrogen 2.944 N/A SER 156.A N ASP 154.A OD1 no hydrogen 3.047 N/A SER 156.A OG ASP 154.A OD1 no hydrogen 2.779 N/A SER 156.A OG ASP 154.A OD2 no hydrogen 3.447 N/A LYS 158.A N LEU 150.A O no hydrogen 2.878 N/A LYS 158.A NZ GLU 99.A OE2 no hydrogen 2.818 N/A LEU 159.A N.A ASN 80.A O no hydrogen 2.836 N/A LEU 159.A N.B ASN 80.A O no hydrogen 2.828 N/A THR 160.A N ASN 148.A O no hydrogen 2.959 N/A ASP 161.A N THR 160.A OG1 no hydrogen 2.745 N/A GLY 163.A N ASP 161.A OD1 no hydrogen 3.464 N/A CYS 165.A N.A PHE 162.A O no hydrogen 3.120 N/A CYS 165.A N.B PHE 162.A O no hydrogen 3.104 N/A CYS 165.A SG.A PHE 162.A O no hydrogen 3.143 N/A CYS 165.A SG.B ILE 140.A O no hydrogen 3.591 N/A CYS 165.A SG.B HIS 141.A O no hydrogen 3.882 N/A ALA 166.A N ILE 140.A O no hydrogen 2.930 N/A GLN 167.A NE2 ASN 68.A OD1 no hydrogen 3.210 N/A ILE 168.A N GLN 138.A O no hydrogen 2.932 N/A THR 169.A N GLN 172.A O no hydrogen 3.120 N/A GLU 171.A N GLU 171.A OE2 no hydrogen 2.709 N/A GLN 172.A N THR 169.A O no hydrogen 3.260 N/A GLN 172.A N THR 169.A OG1 no hydrogen 3.024 N/A ARG 175.A N TYR 194.A O no hydrogen 2.919 N/A THR 180.A OG1 ASP 143.A OD1 no hydrogen 2.735 N/A TYR 182.A OH GLU 220.A O no hydrogen 2.729 N/A TRP 183.A N THR 180.A O no hydrogen 2.889 N/A TRP 183.A NE1 GLU 209.A OE1 no hydrogen 2.827 N/A MET 184.A N PRO 181.A O no hydrogen 3.041 N/A GLU 187.A N GLU 187.A OE2 no hydrogen 2.826 N/A VAL 188.A N ALA 185.A O no hydrogen 2.972 N/A VAL 189.A N ALA 185.A O no hydrogen 3.096 N/A THR 190.A N PRO 186.A O no hydrogen 2.953 N/A THR 190.A OG1 PRO 186.A O no hydrogen 2.801 N/A ARG 191.A N VAL 188.A O no hydrogen 3.002 N/A LYS 192.A N GLU 187.A O no hydrogen 2.969 N/A LYS 192.A NZ THR 190.A OG1 no hydrogen 2.769 N/A TYR 194.A N ARG 175.A O no hydrogen 2.907 N/A LYS 197.A NZ VAL 259.A O no hydrogen 3.042 N/A LYS 197.A NZ ARG 262.A O no hydrogen 2.671 N/A VAL 198.A N GLY 195.A O no hydrogen 3.135 N/A ASP 199.A N PRO 196.A O no hydrogen 2.987 N/A ILE 200.A N LYS 197.A O no hydrogen 3.134 N/A TRP 201.A N LYS 197.A O no hydrogen 3.247 N/A SER 202.A N VAL 198.A O no hydrogen 3.067 N/A SER 202.A OG TRP 183.A O no hydrogen 2.743 N/A SER 202.A OG VAL 198.A O no hydrogen 3.196 N/A LEU 203.A N ASP 199.A O no hydrogen 2.881 N/A GLY 204.A N ILE 200.A O no hydrogen 2.944 N/A ILE 205.A N TRP 201.A O no hydrogen 2.997 N/A MET 206.A N SER 202.A O no hydrogen 2.888 N/A ALA 207.A N LEU 203.A O no hydrogen 2.821 N/A ILE 208.A N GLY 204.A O no hydrogen 3.054 N/A GLU 209.A N ILE 205.A O no hydrogen 2.912 N/A MET 210.A N MET 206.A O no hydrogen 2.991 N/A VAL 211.A N ALA 207.A O no hydrogen 3.187 N/A VAL 211.A N ILE 208.A O no hydrogen 2.987 N/A GLU 212.A N ILE 208.A O no hydrogen 2.756 N/A GLY 213.A N GLU 209.A O no hydrogen 2.787 N/A GLU 220.A N TYR 217.A O no hydrogen 2.870 N/A ALA 225.A N ASN 221.A O no hydrogen 2.965 N/A LEU 226.A N PRO 222.A O no hydrogen 2.923 N/A TYR 227.A N LEU 223.A O no hydrogen 3.171 N/A LEU 228.A N ARG 224.A O no hydrogen 2.921 N/A ILE 229.A N ALA 225.A O no hydrogen 2.833 N/A ALA 230.A N LEU 226.A O no hydrogen 3.036 N/A THR 231.A N TYR 227.A O no hydrogen 3.045 N/A THR 231.A OG1 TYR 227.A O no hydrogen 2.936 N/A THR 231.A OG1 LEU 228.A O no hydrogen 3.532 N/A ASN 232.A N LEU 228.A O no hydrogen 2.845 N/A ASN 232.A ND2 TYR 217.A OH no hydrogen 2.900 N/A GLY 233.A N ILE 229.A O no hydrogen 3.331 N/A THR 234.A OG1 LEU 255.A O no hydrogen 2.577 N/A GLN 238.A N GLU 212.A OE2 no hydrogen 2.722 N/A ASN 239.A ND2 GLU 241.A OE2 no hydrogen 3.162 N/A GLU 241.A N GLU 241.A OE1 no hydrogen 2.725 N/A ARG 242.A N ASN 239.A O no hydrogen 3.001 N/A LEU 243.A N PRO 240.A O no hydrogen 3.087 N/A SER 244.A N GLU 117.A OE2 no hydrogen 2.772 N/A SER 244.A OG GLU 117.A OE1 no hydrogen 2.551 N/A SER 244.A OG GLU 117.A OE2 no hydrogen 3.431 N/A PHE 247.A N SER 244.A OG no hydrogen 3.118 N/A ARG 248.A N SER 244.A O no hydrogen 2.960 N/A ARG 248.A NH2 PRO 240.A O no hydrogen 3.356 N/A ASP 249.A N ALA 245.A O no hydrogen 2.923 N/A PHE 250.A N VAL 246.A O no hydrogen 3.036 N/A LEU 251.A N PHE 247.A O no hydrogen 2.975 N/A ASN 252.A N ARG 248.A O no hydrogen 2.945 N/A ARG 253.A N.A ASP 249.A O no hydrogen 2.967 N/A ARG 253.A N.A PHE 250.A O no hydrogen 3.165 N/A ARG 253.A N.B ASP 249.A O no hydrogen 2.976 N/A ARG 253.A NE.B ASP 249.A OD2 no hydrogen 2.844 N/A ARG 253.A NH2.A ARG 261.A O no hydrogen 2.583 N/A CYS 254.A N PHE 250.A O no hydrogen 3.037 N/A CYS 254.A SG PHE 250.A O no hydrogen 3.499 N/A LEU 255.A N LEU 251.A O no hydrogen 2.980 N/A ASP 260.A N ASP 258.A OD1 no hydrogen 2.929 N/A ARG 261.A NH2 GLU 256.A OE2 no hydrogen 2.771 N/A ARG 262.A N ASP 258.A O no hydrogen 2.959 N/A ARG 262.A N VAL 259.A O no hydrogen 3.217 N/A ARG 262.A NE GLU 256.A O no hydrogen 2.907 N/A ARG 262.A NH1 GLU 187.A OE1 no hydrogen 2.750 N/A ARG 262.A NH1 GLU 187.A OE2 no hydrogen 3.563 N/A ARG 262.A NH1 LYS 197.A O no hydrogen 2.954 N/A ARG 262.A NH2 GLU 187.A OE1 no hydrogen 3.547 N/A ARG 262.A NH2 GLU 187.A OE2 no hydrogen 2.887 N/A ARG 262.A NH2 GLU 256.A O no hydrogen 2.997 N/A GLY 263.A N ARG 253.A O.A no hydrogen 3.152 N/A GLY 263.A N ARG 253.A O.B no hydrogen 3.083 N/A SER 264.A N GLU 267.A OE1 no hydrogen 2.970 N/A GLU 267.A N SER 264.A OG no hydrogen 3.115 N/A LEU 268.A N SER 264.A O no hydrogen 2.877 N/A LEU 269.A N ALA 265.A O no hydrogen 2.957 N/A GLN 270.A N GLU 267.A O no hydrogen 2.993 N/A GLN 270.A NE2 LYS 266.A O no hydrogen 3.120 N/A HIS 271.A N LEU 268.A O no hydrogen 3.012 N/A HIS 271.A NE2 ASP 249.A OD2 no hydrogen 2.697 N/A PHE 273.A N HIS 271.A ND1 no hydrogen 3.001 N/A LEU 274.A N HIS 271.A O no hydrogen 3.090 N/A LYS 275.A N.A PRO 272.A O no hydrogen 3.027 N/A LYS 275.A N.B PRO 272.A O no hydrogen 3.028 N/A LEU 276.A N PHE 273.A O no hydrogen 3.068 N/A ASP 277.A N LEU 274.A O no hydrogen 3.179 N/A LYS 278.A N GLY 118.A O no hydrogen 3.140 N/A LYS 278.A NZ ASP 116.A OD2 no hydrogen 2.658 N/A SER 282.A N PRO 279.A O no hydrogen 2.941 N/A SER 282.A OG PRO 279.A O no hydrogen 2.768 N/A LEU 283.A N LEU 280.A O no hydrogen 2.855 N/A THR 284.A N SER 281.A O no hydrogen 3.122 N/A THR 284.A OG1 MET 153.A O no hydrogen 2.697 N/A THR 284.A OG1 SER 281.A O no hydrogen 3.317 N/A ILE 287.A N LEU 283.A O no hydrogen 2.908 N/A ILE 288.A N THR 284.A O no hydrogen 2.980 N/A ALA 289.A N PRO 285.A O no hydrogen 3.015 N/A ALA 290.A N LEU 286.A O no hydrogen 2.894 N/A LYS 291.A N ILE 287.A O no hydrogen 2.998 N/A LYS 291.A NZ ALA 102.A O no hydrogen 2.932 N/A GLU 292.A N ILE 288.A O no hydrogen 2.990 N/A ALA 293.A N ALA 289.A O no hydrogen 3.030 N/A ILE 294.A N ALA 290.A O no hydrogen 2.938 N/A LYS 295.A N LYS 291.A O no hydrogen 2.884 N/A ASN 296.A N GLU 292.A O no hydrogen 2.960 N/A