Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6g3x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A NE ASP 165.A OD1 no hydrogen 3.213 N/A HIS 4.A N ASP 165.A OD2 no hydrogen 3.406 N/A HIS 4.A ND1 ASP 165.A OD2 no hydrogen 2.821 N/A HIS 4.A NE2 TYR 169.A OH no hydrogen 2.740 N/A ARG 5.A N TYR 69.A OH no hydrogen 2.801 N/A ARG 5.A NH1 THR 67.A OG1 no hydrogen 2.655 N/A ARG 5.A NH1 VAL 68.A O no hydrogen 2.928 N/A THR 6.A N SER 9.A OG no hydrogen 3.031 N/A THR 6.A OG1 SER 9.A OG no hydrogen 2.551 N/A LEU 7.A N HIS 45.A NE2 no hydrogen 3.229 N/A SER 9.A N THR 6.A OG1 no hydrogen 3.105 N/A SER 9.A OG THR 6.A O no hydrogen 3.322 N/A SER 9.A OG THR 6.A OG1 no hydrogen 2.551 N/A SER 10.A OG THR 6.A O no hydrogen 3.300 N/A LEU 13.A N SER 10.A O no hydrogen 2.969 N/A TRP 14.A N PRO 11.A O no hydrogen 3.338 N/A ALA 15.A N CYS 66.A O no hydrogen 2.872 N/A ILE 17.A N LEU 64.A O no hydrogen 2.758 N/A CYS 19.A N ASP 62.A O no hydrogen 2.840 N/A CYS 19.A SG PRO 20.A O no hydrogen 3.615 N/A ARG 21.A N GLU 61.A O no hydrogen 2.832 N/A GLU 23.A N PRO 20.A O no hydrogen 3.017 N/A LEU 24.A N ARG 21.A O no hydrogen 3.240 N/A ARG 25.A N GLY 120.A O no hydrogen 2.796 N/A ARG 25.A NE ASP 27.A OD1 no hydrogen 3.184 N/A ARG 25.A NH2 ASP 27.A OD1 no hydrogen 3.356 N/A LEU 28.A N ARG 25.A O no hydrogen 3.117 N/A VAL 29.A N ARG 25.A O no hydrogen 3.020 N/A VAL 29.A N LEU 26.A O no hydrogen 3.236 N/A LEU 30.A N LEU 26.A O no hydrogen 2.796 N/A SER 32.A OG THR 147.A OG1 no hydrogen 3.393 N/A GLY 33.A N SER 35.A O no hydrogen 3.142 N/A GLN 34.A NE2 ARG 122.A O no hydrogen 2.898 N/A ARG 37.A N SER 35.A OG no hydrogen 3.286 N/A ARG 37.A NH1 HIS 170.A O no hydrogen 3.209 N/A ARG 37.A NH2 HIS 170.A O no hydrogen 2.747 N/A TRP 38.A NE1 TYR 90.A OH no hydrogen 3.044 N/A LYS 39.A N SER 47.A O no hydrogen 2.846 N/A ALA 44.A N GLU 40.A OE2 no hydrogen 2.635 N/A HIS 45.A N SER 42.A O no hydrogen 2.850 N/A HIS 45.A ND1 PRO 43.A O no hydrogen 2.700 N/A TRP 46.A N LEU 57.A O no hydrogen 2.841 N/A SER 47.A N LYS 39.A O no hydrogen 2.895 N/A SER 47.A OG THR 56.A OG1 no hydrogen 2.371 N/A GLY 48.A N TRP 55.A O no hydrogen 2.976 N/A LEU 50.A N GLN 53.A O no hydrogen 2.792 N/A GLN 53.A N LEU 50.A O no hydrogen 2.854 N/A GLN 53.A NE2 GLU 83.A OE2 no hydrogen 2.901 N/A TRP 55.A N GLY 48.A O no hydrogen 2.818 N/A THR 56.A N THR 67.A O no hydrogen 2.872 N/A THR 56.A OG1 SER 47.A OG no hydrogen 2.371 N/A THR 56.A OG1 TYR 69.A OH no hydrogen 2.625 N/A LEU 57.A N TRP 46.A O no hydrogen 2.717 N/A THR 58.A N TYR 65.A O no hydrogen 2.970 N/A THR 58.A OG1 ALA 44.A O no hydrogen 2.557 N/A THR 60.A N GLN 63.A O no hydrogen 2.888 N/A THR 60.A OG1 GLN 63.A O no hydrogen 3.406 N/A GLN 63.A N THR 60.A OG1 no hydrogen 2.957 N/A LEU 64.A N ILE 17.A O no hydrogen 2.835 N/A TYR 65.A N THR 58.A O no hydrogen 2.679 N/A CYS 66.A N ALA 15.A O no hydrogen 2.813 N/A CYS 66.A SG ALA 15.A O no hydrogen 3.616 N/A CYS 66.A SG LEU 64.A O no hydrogen 3.593 N/A THR 67.A N THR 56.A O no hydrogen 3.000 N/A THR 67.A OG1 LEU 13.A O no hydrogen 2.712 N/A TYR 69.A N VAL 54.A O no hydrogen 2.935 N/A TYR 69.A OH THR 56.A OG1 no hydrogen 2.625 N/A ARG 70.A NE GLU 83.A OE2 no hydrogen 2.920 N/A ARG 70.A NH1 SER 77.A O no hydrogen 3.277 N/A ARG 70.A NH2 ARG 78.A O no hydrogen 2.943 N/A ARG 70.A NH2 GLU 83.A OE1 no hydrogen 2.840 N/A ARG 78.A NH1 TRP 14.A O no hydrogen 3.222 N/A THR 80.A N GLU 83.A OE1 no hydrogen 2.936 N/A GLU 83.A N THR 80.A OG1 no hydrogen 3.233 N/A LEU 84.A N THR 80.A O no hydrogen 2.979 N/A GLU 85.A N LEU 81.A O no hydrogen 2.797 N/A THR 86.A N GLU 82.A O no hydrogen 3.091 N/A THR 86.A OG1 GLU 82.A O no hydrogen 3.522 N/A LEU 87.A N GLU 83.A O no hydrogen 3.416 N/A HIS 88.A N LEU 84.A O no hydrogen 2.955 N/A LYS 89.A N GLU 85.A O no hydrogen 3.038 N/A TYR 90.A N THR 86.A O no hydrogen 2.770 N/A PHE 91.A N LEU 87.A O no hydrogen 2.874 N/A GLN 92.A N LYS 89.A O no hydrogen 2.915 N/A GLN 92.A NE2 LEU 123.A O no hydrogen 2.863 N/A LEU 93.A N HIS 88.A O no hydrogen 3.057 N/A VAL 95.A N GLN 92.A O no hydrogen 3.129 N/A LEU 97.A N GLU 23.A OE1 no hydrogen 2.876 N/A ALA 98.A N GLU 23.A OE2 no hydrogen 2.866 N/A GLN 99.A N SER 96.A OG no hydrogen 3.401 N/A TYR 101.A N LEU 97.A O no hydrogen 2.845 N/A TYR 101.A OH PHE 118.A O no hydrogen 2.939 N/A SER 102.A N ALA 98.A O no hydrogen 3.070 N/A HIS 103.A N GLN 99.A O no hydrogen 3.080 N/A TRP 104.A N LEU 100.A O no hydrogen 2.915 N/A ALA 105.A N TYR 101.A O no hydrogen 2.919 N/A SER 106.A N SER 102.A O no hydrogen 3.141 N/A SER 106.A OG HIS 103.A O no hydrogen 2.826 N/A ASP 108.A N ALA 105.A O no hydrogen 3.247 N/A HIS 110.A N ASP 108.A OD1 no hydrogen 2.937 N/A HIS 110.A ND1 TYR 270.A OH no hydrogen 3.337 N/A PHE 111.A N ASP 108.A OD1 no hydrogen 3.104 N/A GLN 112.A N ASP 108.A O no hydrogen 3.266 N/A VAL 114.A N HIS 110.A O no hydrogen 3.064 N/A ALA 115.A N PHE 111.A O no hydrogen 2.734 N/A GLN 116.A NE2 GLN 112.A O no hydrogen 3.576 N/A GLN 116.A NE2 ARG 113.A O no hydrogen 3.377 N/A PHE 118.A N ALA 115.A O no hydrogen 3.138 N/A VAL 121.A N TYR 101.A OH no hydrogen 3.287 N/A ARG 122.A NE GLU 23.A O no hydrogen 2.662 N/A ARG 122.A NH1 PHE 91.A O no hydrogen 2.971 N/A ARG 122.A NH1 VAL 95.A O no hydrogen 3.446 N/A ARG 122.A NH2 GLU 23.A O no hydrogen 2.920 N/A ARG 122.A NH2 VAL 95.A O no hydrogen 3.239 N/A LEU 124.A N GLN 34.A OE1 no hydrogen 2.915 N/A ARG 125.A N TYR 90.A O no hydrogen 2.815 N/A ARG 125.A NE ASP 251.A OD1 no hydrogen 2.875 N/A ARG 125.A NE ASP 251.A OD2 no hydrogen 3.166 N/A ARG 125.A NH2 ASP 251.A OD2 no hydrogen 3.261 N/A GLN 126.A N MET 248.A O no hydrogen 2.797 N/A GLN 126.A NE2 GLN 34.A O no hydrogen 2.925 N/A GLU 130.A N ASP 127.A OD2 no hydrogen 3.253 N/A CYS 131.A N ASP 127.A O no hydrogen 2.972 N/A LEU 132.A N PRO 128.A O no hydrogen 2.826 N/A PHE 133.A N THR 129.A O no hydrogen 3.101 N/A SER 134.A N GLU 130.A O no hydrogen 2.910 N/A SER 134.A OG GLU 130.A O no hydrogen 2.753 N/A PHE 135.A N CYS 131.A O no hydrogen 3.002 N/A ILE 136.A N LEU 132.A O no hydrogen 3.014 N/A CYS 137.A N PHE 133.A O no hydrogen 3.325 N/A CYS 137.A SG PHE 133.A O no hydrogen 3.341 N/A SER 138.A N PHE 135.A O no hydrogen 2.996 N/A SER 138.A OG PHE 135.A O no hydrogen 2.636 N/A SER 139.A OG TYR 194.A OH no hydrogen 2.762 N/A ASN 140.A ND2 TYR 194.A OH no hydrogen 3.080 N/A ASN 141.A ND2 CYS 137.A O no hydrogen 2.706 N/A ASN 142.A N ASN 141.A OD1 no hydrogen 2.970 N/A ARG 145.A N ASN 142.A OD1 no hydrogen 2.804 N/A ILE 146.A N ASN 142.A O no hydrogen 2.822 N/A THR 147.A N ILE 143.A O no hydrogen 3.000 N/A THR 147.A OG1 SER 32.A OG no hydrogen 3.393 N/A THR 147.A OG1 ILE 143.A O no hydrogen 2.668 N/A GLY 148.A N ALA 144.A O no hydrogen 3.295 N/A MET 149.A N ARG 145.A O no hydrogen 3.042 N/A VAL 150.A N ILE 146.A O no hydrogen 2.818 N/A GLU 151.A N THR 147.A O no hydrogen 2.960 N/A ARG 152.A N GLY 148.A O no hydrogen 2.958 N/A ARG 152.A NE LEU 190.A O no hydrogen 2.760 N/A ARG 152.A NH2 LEU 190.A O no hydrogen 3.011 N/A LEU 153.A N MET 149.A O no hydrogen 2.938 N/A CYS 154.A N VAL 150.A O no hydrogen 2.905 N/A CYS 154.A SG VAL 150.A O no hydrogen 3.468 N/A GLN 155.A N GLU 151.A O no hydrogen 2.820 N/A ALA 156.A N ARG 152.A O no hydrogen 3.066 N/A PHE 157.A N LEU 153.A O no hydrogen 3.064 N/A GLY 158.A N CYS 154.A O no hydrogen 2.822 N/A LEU 161.A N TYR 169.A O no hydrogen 2.703 N/A GLN 163.A NE2 ASP 165.A O no hydrogen 3.233 N/A LEU 164.A N VAL 167.A O no hydrogen 2.806 N/A ASP 165.A N MET 2.A O no hydrogen 2.874 N/A VAL 167.A N LEU 164.A O no hydrogen 2.822 N/A TYR 169.A N ILE 162.A O no hydrogen 2.709 N/A TYR 169.A OH HIS 4.A NE2 no hydrogen 2.740 N/A HIS 170.A ND1 GLY 158.A O no hydrogen 2.930 N/A GLY 171.A N PRO 159.A O no hydrogen 2.785 N/A ALA 177.A N ASN 174.A OD1 no hydrogen 2.821 N/A LEU 178.A N LEU 175.A O no hydrogen 2.992 N/A ALA 179.A N HIS 176.A O no hydrogen 3.249 N/A GLU 182.A N GLU 182.A OE2 no hydrogen 2.810 N/A ALA 183.A N GLY 180.A O no hydrogen 3.116 N/A HIS 186.A N GLU 182.A O no hydrogen 2.933 N/A LEU 187.A N ALA 183.A O no hydrogen 2.798 N/A ARG 188.A N GLU 184.A O no hydrogen 2.888 N/A ARG 188.A NE GLU 184.A OE2 no hydrogen 3.224 N/A ARG 188.A NH2 GLU 184.A OE2 no hydrogen 3.194 N/A LYS 189.A N THR 185.A O no hydrogen 3.220 N/A LEU 190.A N HIS 186.A O no hydrogen 3.149 N/A LEU 190.A N LEU 187.A O no hydrogen 3.142 N/A GLY 191.A N ARG 188.A O no hydrogen 2.944 N/A LEU 192.A N LEU 187.A O no hydrogen 3.206 N/A TYR 194.A OH SER 139.A OG no hydrogen 2.762 N/A ARG 195.A N LEU 192.A O no hydrogen 3.310 N/A ARG 195.A NE LEU 192.A O no hydrogen 3.057 N/A ARG 195.A NH1 SER 139.A O no hydrogen 2.489 N/A ALA 196.A N GLY 193.A O no hydrogen 2.929 N/A ARG 197.A N TYR 194.A O no hydrogen 3.184 N/A VAL 199.A N ARG 195.A O no hydrogen 3.009 N/A ARG 200.A N ALA 196.A O no hydrogen 3.277 N/A ARG 200.A NE ALA 179.A O no hydrogen 3.329 N/A ARG 200.A NE GLY 180.A O no hydrogen 2.714 N/A ALA 201.A N ARG 197.A O no hydrogen 2.946 N/A SER 202.A N TYR 198.A O no hydrogen 2.819 N/A SER 202.A OG TYR 198.A O no hydrogen 3.206 N/A SER 202.A OG PRO 235.A O no hydrogen 2.726 N/A ALA 203.A N VAL 199.A O no hydrogen 3.079 N/A LYS 204.A N ARG 200.A O no hydrogen 2.926 N/A LYS 204.A NZ GLU 208.A OE1 no hydrogen 3.450 N/A LYS 204.A NZ GLU 208.A OE2 no hydrogen 2.738 N/A ALA 205.A N ALA 201.A O no hydrogen 2.942 N/A ILE 206.A N SER 202.A O no hydrogen 2.983 N/A LEU 207.A N ALA 203.A O no hydrogen 3.114 N/A GLU 208.A N LYS 204.A O no hydrogen 2.758 N/A GLU 209.A N ALA 205.A O no hydrogen 2.886 N/A GLN 210.A N ILE 206.A O no hydrogen 3.158 N/A GLY 212.A N ILE 206.A O no hydrogen 3.091 N/A TRP 215.A N GLY 212.A O no hydrogen 2.944 N/A LEU 216.A N PRO 213.A O no hydrogen 3.012 N/A GLN 217.A N PRO 213.A O no hydrogen 3.481 N/A GLN 218.A N ALA 214.A O no hydrogen 3.086 N/A LEU 219.A N TRP 215.A O no hydrogen 3.096 N/A ARG 220.A N LEU 216.A O no hydrogen 3.235 N/A ARG 220.A NE ALA 249.A O no hydrogen 2.863 N/A ARG 220.A NH2 ALA 249.A O no hydrogen 2.806 N/A VAL 221.A N GLN 217.A O no hydrogen 3.380 N/A VAL 221.A N GLN 218.A O no hydrogen 3.195 N/A ALA 222.A N GLN 218.A O no hydrogen 2.914 N/A TYR 224.A OH ASP 243.A OD1 no hydrogen 2.463 N/A GLU 225.A N GLU 225.A OE1 no hydrogen 2.789 N/A ALA 227.A N PRO 223.A O no hydrogen 3.088 N/A HIS 228.A N TYR 224.A O no hydrogen 2.889 N/A LYS 229.A N GLU 225.A O no hydrogen 3.140 N/A ALA 230.A N GLU 226.A O no hydrogen 2.933 N/A LEU 231.A N ALA 227.A O no hydrogen 2.952 N/A CYS 232.A N HIS 228.A O no hydrogen 3.110 N/A CYS 232.A SG HIS 228.A O no hydrogen 3.393 N/A THR 233.A N ALA 230.A O no hydrogen 3.085 N/A THR 233.A OG1 ALA 230.A O no hydrogen 2.628 N/A LEU 234.A N LEU 231.A O no hydrogen 3.016 N/A VAL 237.A N LEU 234.A O no hydrogen 3.037 N/A ALA 242.A N GLY 238.A O no hydrogen 2.889 N/A ASP 243.A N ALA 239.A O no hydrogen 2.894 N/A CYS 244.A N LYS 240.A O no hydrogen 2.865 N/A CYS 244.A SG LYS 240.A O no hydrogen 3.297 N/A ILE 245.A N VAL 241.A O no hydrogen 3.026 N/A CYS 246.A N ALA 242.A O no hydrogen 2.861 N/A CYS 246.A SG ALA 242.A O no hydrogen 3.257 N/A LEU 247.A N ASP 243.A O no hydrogen 2.954 N/A MET 248.A N CYS 244.A O no hydrogen 2.983 N/A ALA 249.A N ILE 245.A O no hydrogen 2.927 N/A LEU 250.A N ILE 245.A O no hydrogen 3.133 N/A LEU 250.A N CYS 246.A O no hydrogen 3.360 N/A LYS 252.A N CYS 246.A O no hydrogen 2.978 N/A LYS 252.A NZ LEU 219.A O no hydrogen 2.850 N/A LYS 252.A NZ ALA 222.A O no hydrogen 2.553 N/A LYS 252.A NZ LEU 250.A O no hydrogen 2.873 N/A GLN 254.A N GLN 254.A OE1 no hydrogen 2.798 N/A ALA 255.A N LYS 252.A O no hydrogen 3.051 N/A HIS 261.A N ASP 259.A OD1 no hydrogen 2.805 N/A VAL 262.A N ASP 259.A OD1 no hydrogen 3.097 N/A TRP 263.A N ASP 259.A O no hydrogen 2.924 N/A GLN 264.A N VAL 260.A O no hydrogen 3.074 N/A ILE 265.A N HIS 261.A O no hydrogen 3.071 N/A ALA 266.A N VAL 262.A O no hydrogen 2.902 N/A HIS 267.A N TRP 263.A O no hydrogen 2.893 N/A ARG 268.A N GLN 264.A O no hydrogen 2.856 N/A ARG 268.A NE ASP 269.A OD1 no hydrogen 2.841 N/A ARG 268.A NH2 ASP 269.A OD1 no hydrogen 3.480 N/A ARG 268.A NH2 ASP 269.A OD2 no hydrogen 2.997 N/A ARG 268.A NH2 ASP 311.A OD1 no hydrogen 3.118 N/A ASP 269.A N ILE 265.A O no hydrogen 2.775 N/A TYR 270.A N ALA 266.A O no hydrogen 2.926 N/A TYR 270.A OH ASP 108.A OD1 no hydrogen 3.420 N/A TYR 270.A OH ASP 108.A OD2 no hydrogen 2.387 N/A TYR 270.A OH HIS 110.A ND1 no hydrogen 3.337 N/A GLY 271.A N HIS 267.A O no hydrogen 3.066 N/A TRP 272.A N ALA 266.A O no hydrogen 3.205 N/A LYS 275.A N GLU 287.A OE2 no hydrogen 3.006 N/A SER 277.A N THR 276.A OG1 no hydrogen 2.767 N/A ALA 284.A N SER 281.A OG no hydrogen 3.374 N/A ASN 285.A N SER 281.A O no hydrogen 2.763 N/A LYS 286.A N PRO 282.A O no hydrogen 3.119 N/A GLU 287.A N LEU 283.A O no hydrogen 3.023 N/A LEU 288.A N ALA 284.A O no hydrogen 3.015 N/A GLY 289.A N ASN 285.A O no hydrogen 3.059 N/A ASN 290.A N LYS 286.A O no hydrogen 2.796 N/A PHE 291.A N GLU 287.A O no hydrogen 2.764 N/A PHE 292.A N LEU 288.A O no hydrogen 3.115 N/A ARG 293.A N GLY 289.A O no hydrogen 3.144 N/A ARG 293.A NH1 GLN 254.A O no hydrogen 2.846 N/A ARG 293.A NH2 ASN 290.A OD1 no hydrogen 2.991 N/A ASN 294.A N ASN 290.A O no hydrogen 2.851 N/A LEU 295.A N PHE 291.A O no hydrogen 2.944 N/A TRP 296.A N PHE 292.A O no hydrogen 2.845 N/A TRP 296.A NE1 ASP 108.A OD2 no hydrogen 2.833 N/A GLY 297.A N ARG 293.A O no hydrogen 2.881 N/A ALA 300.A N GLY 297.A O no hydrogen 3.091 N/A GLY 301.A N PRO 253.A O no hydrogen 2.872 N/A TRP 302.A N TYR 299.A O no hydrogen 2.946 N/A ALA 303.A N TYR 299.A O no hydrogen 3.262 N/A GLN 304.A N ALA 300.A O no hydrogen 3.003 N/A ALA 305.A N GLY 301.A O no hydrogen 3.149 N/A VAL 306.A N TRP 302.A O no hydrogen 3.361 N/A LEU 307.A N ALA 303.A O no hydrogen 3.257 N/A PHE 308.A N GLN 304.A O no hydrogen 2.870 N/A SER 309.A N ALA 305.A O no hydrogen 2.994 N/A ALA 310.A N VAL 306.A O no hydrogen 3.002 N/A ASP 311.A N LEU 307.A O no hydrogen 3.002 N/A LEU 312.A N PHE 308.A O no hydrogen 3.137 N/A ARG 313.A N SER 309.A O no hydrogen 3.307 N/A