Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6gzd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N TYR 9.A O no hydrogen 3.194 N/A LYS 8.A N VAL 5.A O no hydrogen 3.146 N/A TYR 9.A N VAL 5.A O no hydrogen 3.126 N/A LYS 10.A N THR 27.A O no hydrogen 2.896 N/A LEU 11.A N PHE 3.A O no hydrogen 2.911 N/A GLY 12.A N LEU 25.A O no hydrogen 2.793 N/A ILE 15.A N ILE 23.A O no hydrogen 2.931 N/A SER 17.A OG GLY 21.A O no hydrogen 3.424 N/A GLY 18.A N GLY 21.A O no hydrogen 2.907 N/A ASP 22.A N LEU 39.A O no hydrogen 3.184 N/A ILE 23.A N GLY 16.A O no hydrogen 3.007 N/A TYR 24.A N VAL 37.A O no hydrogen 2.740 N/A LEU 25.A N ARG 13.A O no hydrogen 3.110 N/A ALA 26.A N VAL 35.A O no hydrogen 2.847 N/A THR 27.A N LYS 10.A O no hydrogen 3.063 N/A ASN 28.A N GLU 33.A O no hydrogen 2.820 N/A ILE 29.A N LYS 8.A O no hydrogen 2.898 N/A THR 30.A N ASN 28.A OD1 no hydrogen 2.945 N/A THR 30.A OG1 ASN 28.A OD1 no hydrogen 2.709 N/A GLY 32.A N ASN 28.A O no hydrogen 2.702 N/A GLU 33.A N ASN 31.A OD1 no hydrogen 3.038 N/A VAL 35.A N ALA 26.A O no hydrogen 2.919 N/A ALA 36.A N MET 82.A O no hydrogen 2.880 N/A VAL 37.A N TYR 24.A O no hydrogen 2.774 N/A LYS 38.A N LEU 80.A O no hydrogen 2.705 N/A LYS 38.A NZ GLU 52.A OE1 no hydrogen 3.131 N/A LYS 38.A NZ GLU 52.A OE2 no hydrogen 3.556 N/A LEU 39.A N ASP 22.A O no hydrogen 2.889 N/A GLU 40.A N ASN 78.A O no hydrogen 2.916 N/A SER 41.A OG LYS 43.A O.B no hydrogen 3.078 N/A GLN 42.A N.A ASP 76.A O no hydrogen 2.776 N/A GLN 42.A N.B ASP 76.A O no hydrogen 2.794 N/A ARG 45.A N.A ALA 44.A O.B no hydrogen 1.580 N/A GLN 48.A N GLU 40.A OE2 no hydrogen 3.328 N/A GLN 48.A NE2 GLU 40.A OE2 no hydrogen 2.687 N/A LEU 49.A N GLU 40.A OE1 no hydrogen 3.219 N/A TYR 51.A OH ALA 153.A O no hydrogen 2.529 N/A GLU 52.A N GLN 48.A O no hydrogen 3.023 N/A SER 53.A N LEU 49.A O no hydrogen 2.889 N/A SER 53.A OG HIS 50.A O no hydrogen 2.967 N/A LYS 54.A N HIS 50.A O no hydrogen 3.067 N/A LEU 55.A N TYR 51.A O no hydrogen 3.066 N/A TYR 56.A N GLU 52.A O no hydrogen 2.957 N/A LYS 57.A N SER 53.A O no hydrogen 3.097 N/A ILE 58.A N LYS 54.A O no hydrogen 3.088 N/A LEU 59.A N LEU 55.A O no hydrogen 2.961 N/A GLN 60.A N LYS 57.A O no hydrogen 3.343 N/A GLN 60.A NE2 TYR 56.A O no hydrogen 2.811 N/A GLN 60.A NE2 PRO 66.A O no hydrogen 2.939 N/A GLY 62.A N LEU 59.A O no hydrogen 3.180 N/A ILE 65.A N GLY 62.A O no hydrogen 3.418 N/A HIS 67.A N ASP 83.A OD2 no hydrogen 3.235 N/A ILE 68.A N GLN 60.A OE1 no hydrogen 3.427 N/A ARG 69.A N VAL 81.A O no hydrogen 2.802 N/A ARG 69.A NH1 HIS 67.A O no hydrogen 3.524 N/A ARG 69.A NH1 ASP 83.A OD1 no hydrogen 2.347 N/A ARG 69.A NH2 GLU 33.A OE2 no hydrogen 3.025 N/A TRP 70.A N VAL 81.A O no hydrogen 3.502 N/A GLY 72.A N VAL 79.A O no hydrogen 3.005 N/A GLN 73.A NE2 ASN 78.A OD1 no hydrogen 2.880 N/A GLU 74.A N TYR 77.A O no hydrogen 2.973 N/A LYS 75.A NZ GLU 2.A O no hydrogen 3.178 N/A TYR 77.A N GLU 74.A O no hydrogen 3.126 N/A ASN 78.A N GLU 40.A O no hydrogen 2.647 N/A ASN 78.A ND2 GLU 40.A OE1 no hydrogen 3.532 N/A VAL 79.A N GLY 72.A O no hydrogen 2.684 N/A LEU 80.A N LYS 38.A O no hydrogen 2.942 N/A VAL 81.A N TRP 70.A O no hydrogen 2.908 N/A MET 82.A N ALA 36.A O no hydrogen 2.822 N/A ASP 83.A N HIS 67.A O no hydrogen 3.135 N/A GLY 86.A N MET 136.A O no hydrogen 2.765 N/A SER 88.A N ASP 91.A OD2 no hydrogen 3.231 N/A LEU 89.A N PRO 131.A O no hydrogen 3.237 N/A LEU 89.A N PHE 134.A O no hydrogen 2.900 N/A ASP 91.A N SER 88.A OG no hydrogen 3.009 N/A LEU 92.A N SER 88.A O no hydrogen 3.126 N/A PHE 93.A N LEU 89.A O no hydrogen 2.872 N/A ASN 94.A N GLU 90.A O no hydrogen 3.012 N/A PHE 95.A N ASP 91.A O no hydrogen 2.958 N/A CYS 96.A N LEU 92.A O no hydrogen 3.028 N/A CYS 96.A N PHE 93.A O no hydrogen 3.228 N/A CYS 96.A SG LEU 92.A O no hydrogen 3.380 N/A SER 97.A N ASN 94.A O no hydrogen 2.918 N/A ARG 98.A N PHE 93.A O no hydrogen 2.753 N/A ARG 98.A NH1 TYR 205.A OH no hydrogen 2.705 N/A ARG 98.A NH2 GLU 90.A OE2 no hydrogen 3.087 N/A ARG 98.A NH2 ASN 94.A OD1 no hydrogen 2.897 N/A THR 101.A N ASP 289.A OD2 no hydrogen 2.743 N/A THR 101.A OG1 ASP 289.A OD1 no hydrogen 2.617 N/A THR 101.A OG1 ASP 289.A OD2 no hydrogen 3.143 N/A LYS 103.A NZ GLN 283.A O no hydrogen 3.494 N/A LYS 103.A NZ ASP 285.A OD1 no hydrogen 2.952 N/A LYS 103.A NZ ASP 285.A OD2 no hydrogen 3.390 N/A THR 104.A N THR 101.A OG1 no hydrogen 3.344 N/A VAL 105.A N THR 101.A O no hydrogen 3.035 N/A LEU 106.A N MET 102.A O no hydrogen 2.987 N/A MET 107.A N LYS 103.A O no hydrogen 3.027 N/A LEU 108.A N THR 104.A O no hydrogen 2.994 N/A ALA 109.A N VAL 105.A O no hydrogen 2.931 N/A ASP 110.A N LEU 106.A O no hydrogen 3.245 N/A GLN 111.A NE2 ASN 143.A O no hydrogen 3.070 N/A MET 112.A N LEU 108.A O no hydrogen 2.860 N/A ILE 113.A N ALA 109.A O no hydrogen 3.070 N/A SER 114.A OG.B ASP 110.A O no hydrogen 3.249 N/A ARG 115.A N GLN 111.A O no hydrogen 2.889 N/A ARG 115.A NH1 GLN 111.A OE1 no hydrogen 3.152 N/A ARG 115.A NH1 LEU 145.A O no hydrogen 2.914 N/A ARG 115.A NH2 SER 114.A OG.A no hydrogen 3.281 N/A ILE 116.A N MET 112.A O no hydrogen 3.136 N/A GLU 117.A N ILE 113.A O no hydrogen 2.891 N/A TYR 118.A N SER 114.A O.A no hydrogen 3.059 N/A TYR 118.A N SER 114.A O.B no hydrogen 3.034 N/A VAL 119.A N ARG 115.A O no hydrogen 3.477 N/A HIS 120.A N ILE 116.A O no hydrogen 3.120 N/A HIS 120.A ND1 TYR 266.A OH no hydrogen 2.737 N/A HIS 120.A NE2 ASP 195.A OD2 no hydrogen 2.804 N/A THR 121.A N GLU 117.A O no hydrogen 2.938 N/A THR 121.A OG1 TYR 118.A O no hydrogen 2.745 N/A LYS 122.A N TYR 118.A O no hydrogen 3.329 N/A LYS 122.A N VAL 119.A O no hydrogen 3.234 N/A ASN 123.A N HIS 120.A O no hydrogen 2.997 N/A ASN 123.A ND2 ASN 159.A OD1 no hydrogen 2.645 N/A PHE 124.A N VAL 119.A O no hydrogen 3.202 N/A ILE 125.A N LYS 154.A O no hydrogen 2.984 N/A HIS 126.A N ASP 195.A OD2 no hydrogen 2.866 N/A HIS 126.A NE2 ILE 148.A O no hydrogen 2.911 N/A ARG 127.A N ASP 195.A OD1 no hydrogen 3.125 N/A ARG 127.A NE LEU 152.A O no hydrogen 2.816 N/A ARG 127.A NH2 LEU 152.A O no hydrogen 2.899 N/A ASP 128.A N HIS 126.A ND1 no hydrogen 3.238 N/A ASN 133.A N LYS 130.A O no hydrogen 3.005 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 2.731 N/A PHE 134.A N PRO 131.A O no hydrogen 3.266 N/A LEU 135.A N PHE 146.A O no hydrogen 2.844 N/A MET 136.A N PRO 87.A O no hydrogen 3.048 N/A GLY 137.A N LYS 144.A O no hydrogen 3.001 N/A HIS 141.A N ILE 138.A O no hydrogen 3.127 N/A CYS 142.A N GLY 139.A O no hydrogen 3.345 N/A LYS 144.A N HIS 141.A O no hydrogen 3.080 N/A LEU 145.A N GLN 111.A OE1 no hydrogen 2.928 N/A PHE 146.A N LEU 135.A O no hydrogen 2.721 N/A ILE 148.A N ASN 133.A O no hydrogen 2.980 N/A ASP 149.A N TYR 56.A OH no hydrogen 3.196 N/A PHE 150.A N GLU 52.A OE2 no hydrogen 3.049 N/A GLY 151.A N ASP 149.A OD1 no hydrogen 3.460 N/A ALA 153.A N PHE 150.A O no hydrogen 3.253 N/A LYS 154.A N ILE 125.A O no hydrogen 3.073 N/A LYS 154.A NZ GLU 189.A OE2 no hydrogen 3.042 N/A LYS 155.A NZ ASN 159.A OD1 no hydrogen 3.490 N/A TYR 156.A N ASN 123.A O no hydrogen 2.978 N/A TYR 156.A OH HIS 120.A O no hydrogen 2.673 N/A ARG 157.A NE ASN 123.A OD1 no hydrogen 2.996 N/A ASP 158.A N GLN 163.A O no hydrogen 3.053 N/A THR 161.A N ASP 158.A OD2 no hydrogen 2.781 N/A THR 161.A OG1 ASP 158.A OD2 no hydrogen 2.981 N/A ARG 162.A N ASP 158.A O no hydrogen 2.987 N/A GLN 163.A N THR 161.A OG1 no hydrogen 3.221 N/A ILE 165.A N TYR 156.A O no hydrogen 2.863 N/A ARG 168.A NE GLU 169.A O no hydrogen 2.951 N/A ARG 168.A NH2 GLU 169.A O no hydrogen 2.625 N/A LYS 171.A N GLY 187.A O no hydrogen 2.897 N/A LYS 171.A NZ GLU 189.A OE1 no hydrogen 3.424 N/A THR 176.A OG1 ASP 128.A OD1 no hydrogen 3.057 N/A ARG 178.A NH1 TYR 179.A OH no hydrogen 2.886 N/A SER 181.A OG ASP 194.A OD1 no hydrogen 2.617 N/A ILE 182.A N GLU 197.A OE2 no hydrogen 2.976 N/A ALA 184.A N SER 181.A OG no hydrogen 3.143 N/A HIS 185.A N SER 181.A O no hydrogen 3.259 N/A LEU 186.A N ILE 182.A O no hydrogen 3.268 N/A GLY 187.A N ALA 184.A O no hydrogen 3.120 N/A ILE 188.A N ASN 183.A O no hydrogen 3.043 N/A GLU 189.A N ARG 168.A O no hydrogen 2.943 N/A SER 191.A N ASP 194.A OD2 no hydrogen 2.816 N/A SER 191.A OG PHE 260.A O no hydrogen 2.695 N/A ARG 192.A NH2 GLU 261.A O no hydrogen 2.970 N/A ARG 193.A NH1 LEU 258.A O no hydrogen 2.897 N/A ARG 193.A NH2 TYR 167.A OH no hydrogen 3.332 N/A ASP 194.A N SER 191.A O no hydrogen 3.033 N/A MET 196.A N ARG 192.A O no hydrogen 3.342 N/A GLU 197.A N ARG 193.A O no hydrogen 2.903 N/A SER 198.A N ASP 194.A O no hydrogen 3.017 N/A SER 198.A OG TYR 179.A O no hydrogen 2.662 N/A SER 198.A OG ASP 194.A O no hydrogen 3.202 N/A LEU 199.A N ASP 195.A O no hydrogen 3.083 N/A GLY 200.A N MET 196.A O no hydrogen 3.166 N/A TYR 201.A N GLU 197.A O no hydrogen 3.227 N/A TYR 201.A OH GLU 197.A OE2 no hydrogen 2.743 N/A VAL 202.A N SER 198.A O no hydrogen 3.045 N/A LEU 203.A N LEU 199.A O no hydrogen 2.910 N/A MET 204.A N GLY 200.A O no hydrogen 3.081 N/A TYR 205.A N TYR 201.A O no hydrogen 2.868 N/A TYR 205.A OH GLU 90.A OE1 no hydrogen 2.928 N/A PHE 206.A N VAL 202.A O no hydrogen 3.008 N/A ASN 207.A N LEU 203.A O no hydrogen 2.970 N/A ARG 208.A N MET 204.A O no hydrogen 2.921 N/A ARG 208.A NE SER 210.A O no hydrogen 2.871 N/A ARG 208.A NH1 LEU 240.A O no hydrogen 3.073 N/A THR 209.A N TYR 205.A O no hydrogen 2.855 N/A THR 209.A OG1 ARG 208.A O no hydrogen 2.436 N/A LEU 211.A N GLN 214.A OE1 no hydrogen 2.650 N/A TRP 213.A NE1 ARG 178.A O no hydrogen 2.794 N/A GLN 214.A N LEU 211.A O no hydrogen 2.873 N/A LYS 221.A NZ TYR 225.A OH no hydrogen 3.505 N/A GLN 223.A N THR 220.A OG1 no hydrogen 2.861 N/A LYS 224.A N THR 220.A O no hydrogen 3.077 N/A TYR 225.A N LYS 221.A O no hydrogen 2.962 N/A GLU 226.A N LYS 222.A O no hydrogen 2.913 N/A LYS 227.A N GLN 223.A O no hydrogen 2.938 N/A LYS 227.A NZ LYS 217.A O no hydrogen 2.748 N/A ILE 228.A N LYS 224.A O no hydrogen 2.939 N/A SER 229.A N TYR 225.A O no hydrogen 2.925 N/A GLU 230.A N GLU 226.A O no hydrogen 3.011 N/A LYS 231.A N LYS 227.A O no hydrogen 3.028 N/A LYS 232.A N ILE 228.A O no hydrogen 2.961 N/A LYS 232.A NZ ALA 177.A O no hydrogen 2.543 N/A LYS 232.A NZ ARG 178.A O no hydrogen 3.436 N/A LYS 232.A NZ ALA 180.A O no hydrogen 2.769 N/A LYS 232.A NZ HIS 185.A NE2 no hydrogen 2.922 N/A MET 233.A N SER 229.A O no hydrogen 2.962 N/A SER 234.A N GLU 230.A O no hydrogen 2.983 N/A SER 234.A OG GLU 230.A O no hydrogen 3.063 N/A SER 234.A OG LYS 231.A O no hydrogen 3.484 N/A THR 235.A OG1 LYS 231.A O no hydrogen 2.590 N/A LEU 240.A N PRO 236.A O no hydrogen 2.956 N/A CYS 241.A N VAL 237.A O no hydrogen 2.900 N/A CYS 241.A SG VAL 237.A O no hydrogen 3.234 N/A LYS 242.A N VAL 239.A O no hydrogen 3.290 N/A PHE 244.A N CYS 241.A O no hydrogen 3.339 N/A GLU 247.A N GLU 247.A OE1 no hydrogen 2.818 N/A PHE 248.A N PRO 245.A O no hydrogen 3.260 N/A MET 250.A N ALA 246.A O no hydrogen 2.993 N/A TYR 251.A N GLU 247.A O no hydrogen 2.865 N/A TYR 251.A OH MET 196.A O no hydrogen 2.698 N/A LEU 252.A N PHE 248.A O no hydrogen 3.171 N/A ASN 253.A N ALA 249.A O no hydrogen 2.964 N/A ASN 253.A ND2 GLU 238.A OE2 no hydrogen 3.356 N/A TYR 254.A N MET 250.A O no hydrogen 2.836 N/A CYS 255.A N TYR 251.A O no hydrogen 2.998 N/A CYS 255.A SG TYR 251.A O no hydrogen 3.355 N/A ARG 256.A N LEU 252.A O no hydrogen 3.089 N/A GLY 257.A N ASN 253.A O no hydrogen 2.935 N/A LEU 258.A N TYR 254.A O no hydrogen 3.177 N/A ARG 259.A N GLU 262.A OE1 no hydrogen 2.978 N/A ARG 259.A NE GLY 257.A O no hydrogen 3.179 N/A ARG 259.A NH1 ARG 256.A O no hydrogen 3.252 N/A ARG 259.A NH1 GLY 257.A O no hydrogen 3.303 N/A ARG 259.A NH1 LEU 258.A O no hydrogen 3.174 N/A GLU 262.A N ARG 259.A O no hydrogen 2.966 N/A ASP 265.A N TYR 254.A OH no hydrogen 2.753 N/A TYR 266.A OH HIS 120.A ND1 no hydrogen 2.737 N/A TYR 268.A N ASP 265.A OD1 no hydrogen 3.127 N/A LEU 269.A N ASP 265.A O no hydrogen 3.121 N/A ARG 270.A N TYR 266.A O no hydrogen 2.895 N/A ARG 270.A NH1 GLU 117.A OE1 no hydrogen 2.733 N/A ARG 270.A NH2 GLU 117.A OE1 no hydrogen 2.872 N/A GLN 271.A N MET 267.A O no hydrogen 2.913 N/A LEU 272.A N TYR 268.A O no hydrogen 2.868 N/A PHE 273.A N LEU 269.A O no hydrogen 3.376 N/A ARG 274.A N ARG 270.A O no hydrogen 2.890 N/A ILE 275.A N GLN 271.A O no hydrogen 2.899 N/A PHE 277.A N PHE 273.A O no hydrogen 2.899 N/A ARG 278.A N ARG 274.A O no hydrogen 2.999 N/A ARG 278.A NH2 GLN 283.A OE1 no hydrogen 2.687 N/A THR 279.A N ILE 275.A O no hydrogen 2.943 N/A THR 279.A OG1 ILE 275.A O no hydrogen 2.810 N/A LEU 280.A N LEU 276.A O no hydrogen 3.004 N/A ASN 281.A N ARG 278.A O no hydrogen 3.165 N/A HIS 282.A N PHE 277.A O no hydrogen 3.198 N/A TYR 284.A N GLN 283.A OE1 no hydrogen 2.845 N/A ASP 285.A N GLN 283.A O no hydrogen 2.872 N/A THR 287.A N ASP 285.A OD1 no hydrogen 3.090 N/A PHE 288.A N THR 291.A OG1 no hydrogen 3.161 N/A ASP 289.A N THR 104.A OG1 no hydrogen 3.014 N/A THR 291.A OG1 TYR 286.A O no hydrogen 3.531 N/A THR 291.A OG1 PHE 288.A O no hydrogen 3.461 N/A MET 292.A N PHE 288.A O no hydrogen 3.274 N/A LEU 293.A N ASP 289.A O no hydrogen 3.407 N/A LYS 294.A N TRP 290.A O no hydrogen 3.103 N/A GLN 295.A N THR 291.A O no hydrogen 3.270 N/A LYS 296.A N MET 292.A O no hydrogen 3.269 N/A ALA 297.A N LEU 293.A O no hydrogen 3.131 N/A