Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6hhh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 6.A N LEU 28.A O no hydrogen 2.602 N/A LYS 7.A N LEU 28.A O no hydrogen 3.284 N/A GLY 9.A N PHE 26.A O no hydrogen 3.147 N/A LEU 11.A N ARG 24.A O no hydrogen 2.938 N/A HIS 12.A N HIS 85.A O no hydrogen 2.902 N/A LYS 13.A N ARG 22.A O no hydrogen 2.963 N/A LYS 13.A NZ ASP 263.A OD1 no hydrogen 3.387 N/A ARG 14.A N THR 83.A O no hydrogen 3.100 N/A ARG 14.A NH1 THR 83.A OG1 no hydrogen 3.402 N/A GLY 15.A N THR 20.A O no hydrogen 3.060 N/A GLU 16.A N ASP 263.A OD1 no hydrogen 3.445 N/A ARG 22.A N LYS 13.A O no hydrogen 2.797 N/A ARG 22.A NH1 LEU 261.A O no hydrogen 3.005 N/A ARG 22.A NH1 ASP 263.A OD2 no hydrogen 3.349 N/A ARG 24.A N LEU 11.A O no hydrogen 2.944 N/A ARG 24.A NE ASP 263.A O no hydrogen 3.110 N/A ARG 24.A NH1 PRO 23.A O no hydrogen 2.499 N/A ARG 24.A NH2 GLU 262.A O no hydrogen 2.936 N/A TYR 25.A N TYR 37.A O no hydrogen 2.767 N/A TYR 25.A OH GLU 8.A OE1 no hydrogen 2.531 N/A PHE 26.A N GLY 9.A O no hydrogen 2.845 N/A LEU 27.A N ILE 35.A O no hydrogen 2.718 N/A LEU 28.A N LYS 7.A O no hydrogen 2.930 N/A LYS 29.A N THR 33.A O no hydrogen 3.295 N/A ASN 30.A N ALA 4.A O no hydrogen 2.959 N/A ASN 30.A ND2 ASP 2.A O no hydrogen 2.701 N/A GLY 32.A N LYS 29.A O no hydrogen 3.005 N/A THR 33.A N ASP 31.A OD1 no hydrogen 2.938 N/A THR 33.A OG1 ASP 31.A OD1 no hydrogen 2.760 N/A THR 33.A OG1 ASP 31.A OD2 no hydrogen 3.507 N/A PHE 34.A N PHE 51.A O no hydrogen 2.936 N/A ILE 35.A N LEU 27.A O no hydrogen 3.169 N/A TYR 37.A N TYR 25.A O no hydrogen 2.676 N/A LYS 38.A NZ GLU 262.A OE2 no hydrogen 2.746 N/A ASN 49.A N ASN 220.A O no hydrogen 2.801 N/A ASN 50.A ND2 VAL 222.A O no hydrogen 2.827 N/A SER 52.A N ASN 49.A O no hydrogen 3.194 N/A VAL 53.A N GLY 32.A O no hydrogen 2.814 N/A ALA 54.A N SER 52.A OG no hydrogen 3.095 N/A CYS 56.A SG SER 52.A O no hydrogen 3.861 N/A CYS 56.A SG ALA 54.A O no hydrogen 3.182 N/A GLN 57.A N ARG 72.A O no hydrogen 2.947 N/A MET 59.A N ILE 70.A O no hydrogen 2.873 N/A LYS 60.A NZ GLU 93.A OE1 no hydrogen 2.530 N/A LYS 60.A NZ GLU 93.A OE2 no hydrogen 3.171 N/A THR 61.A N THR 68.A O no hydrogen 2.910 N/A THR 61.A OG1 ARG 63.A O no hydrogen 2.800 N/A ARG 63.A NH1 GLU 62.A O no hydrogen 3.135 N/A ARG 65.A NH1 HIS 85.A NE2 no hydrogen 3.329 N/A ASN 67.A N GLU 62.A OE1 no hydrogen 2.972 N/A THR 68.A N THR 61.A O no hydrogen 3.167 N/A THR 68.A OG1 ARG 65.A O no hydrogen 2.237 N/A PHE 69.A N PHE 84.A O no hydrogen 3.023 N/A ILE 70.A N MET 59.A O no hydrogen 2.675 N/A ILE 71.A N ARG 82.A O no hydrogen 2.983 N/A ARG 72.A N GLN 57.A O no hydrogen 3.027 N/A ARG 72.A NH1 GLU 81.A OE2 no hydrogen 2.524 N/A CYS 73.A N ILE 80.A O no hydrogen 2.977 N/A CYS 73.A SG SER 52.A O no hydrogen 3.865 N/A GLN 75.A N THR 78.A O no hydrogen 2.893 N/A GLN 75.A NE2 ASN 50.A O no hydrogen 2.898 N/A THR 77.A OG1 ASP 243.A OD1 no hydrogen 2.765 N/A THR 77.A OG1 ASP 243.A OD2 no hydrogen 3.435 N/A THR 78.A N GLN 75.A O no hydrogen 2.932 N/A THR 78.A OG1 GLY 245.A O no hydrogen 3.265 N/A ILE 80.A N CYS 73.A O no hydrogen 2.841 N/A ARG 82.A N ILE 71.A O no hydrogen 2.937 N/A ARG 82.A NH1 PHE 34.A O no hydrogen 3.432 N/A ARG 82.A NH2 PHE 34.A O no hydrogen 2.784 N/A PHE 84.A N PHE 69.A O no hydrogen 2.999 N/A HIS 85.A N HIS 12.A O no hydrogen 2.874 N/A VAL 86.A N ASN 67.A O no hydrogen 3.141 N/A GLU 91.A N THR 88.A O no hydrogen 3.037 N/A GLU 91.A N THR 88.A OG1 no hydrogen 3.375 N/A ARG 92.A N THR 88.A O no hydrogen 3.336 N/A ARG 92.A NH1 GLU 62.A OE2 no hydrogen 2.597 N/A ARG 92.A NH1 THR 68.A O no hydrogen 3.041 N/A ARG 92.A NH2 GLU 62.A OE2 no hydrogen 2.699 N/A GLU 93.A N PRO 89.A O no hydrogen 3.150 N/A GLU 94.A N GLU 90.A O no hydrogen 3.212 N/A TRP 95.A N GLU 91.A O no hydrogen 3.012 N/A THR 96.A N ARG 92.A O no hydrogen 2.834 N/A THR 96.A OG1 ARG 92.A O no hydrogen 3.062 N/A THR 96.A OG1 GLU 93.A O no hydrogen 3.040 N/A THR 97.A N GLU 93.A O no hydrogen 3.005 N/A THR 97.A OG1 GLU 93.A O no hydrogen 2.567 N/A ALA 98.A N GLU 94.A O no hydrogen 3.330 N/A ILE 99.A N TRP 95.A O no hydrogen 3.002 N/A GLN 100.A N THR 96.A O no hydrogen 2.687 N/A GLN 100.A NE2 ASP 104.A OD2 no hydrogen 2.611 N/A THR 101.A N THR 97.A O no hydrogen 2.833 N/A THR 101.A OG1 THR 97.A O no hydrogen 2.646 N/A VAL 102.A N ALA 98.A O no hydrogen 3.153 N/A ALA 103.A N ILE 99.A O no hydrogen 2.816 N/A ASP 104.A N GLN 100.A O no hydrogen 3.004 N/A GLY 105.A N THR 101.A O no hydrogen 2.755 N/A LEU 106.A N ALA 103.A O no hydrogen 3.441 N/A LYS 107.A N ASP 104.A O no hydrogen 3.209 N/A THR 111.A OG1 ASN 113.A OD1 no hydrogen 2.295 N/A GLU 114.A N THR 111.A O no hydrogen 3.280 N/A PHE 115.A N MET 112.A O no hydrogen 3.196 N/A GLU 116.A N LYS 133.A O no hydrogen 2.782 N/A TYR 117.A OH MET 112.A O no hydrogen 2.778 N/A LEU 118.A N LEU 131.A O no hydrogen 3.040 N/A LYS 119.A N LEU 131.A O no hydrogen 3.458 N/A LEU 121.A N VAL 129.A O no hydrogen 2.882 N/A GLY 122.A N VAL 129.A O no hydrogen 3.208 N/A THR 125.A N CYS 247.A O no hydrogen 2.769 N/A THR 125.A OG1 CYS 247.A O no hydrogen 3.276 N/A LYS 128.A N ILE 145.A O no hydrogen 2.762 N/A VAL 129.A N GLY 122.A O no hydrogen 2.686 N/A ILE 130.A N MET 143.A O no hydrogen 2.829 N/A LEU 131.A N LYS 119.A O no hydrogen 2.702 N/A VAL 132.A N TYR 141.A O no hydrogen 2.794 N/A LYS 133.A N GLU 116.A O no hydrogen 2.732 N/A LYS 133.A NZ GLU 116.A OE2 no hydrogen 3.508 N/A GLU 134.A N ARG 139.A O no hydrogen 2.922 N/A LYS 135.A N GLU 114.A O no hydrogen 3.002 N/A LYS 135.A NZ ASN 113.A O no hydrogen 3.076 N/A THR 137.A OG1 GLU 134.A OE2 no hydrogen 3.181 N/A GLY 138.A N GLU 134.A O no hydrogen 2.807 N/A ARG 139.A N THR 137.A OG1 no hydrogen 3.079 N/A TYR 141.A N VAL 132.A O no hydrogen 2.891 N/A ALA 142.A N MET 178.A O no hydrogen 2.771 N/A MET 143.A N ILE 130.A O no hydrogen 2.794 N/A LYS 144.A N PHE 176.A O no hydrogen 2.759 N/A LYS 144.A NZ THR 77.A O no hydrogen 3.463 N/A LYS 144.A NZ THR 77.A OG1 no hydrogen 2.804 N/A LYS 144.A NZ THR 78.A OG1 no hydrogen 2.693 N/A LYS 144.A NZ ASP 243.A O no hydrogen 2.638 N/A LYS 144.A NZ GLY 245.A O no hydrogen 3.274 N/A ILE 145.A N LYS 128.A O no hydrogen 2.698 N/A LEU 146.A N LEU 174.A O no hydrogen 2.751 N/A LYS 147.A N PHE 126.A O no hydrogen 2.979 N/A LYS 148.A N ASP 172.A O no hydrogen 2.982 N/A VAL 150.A N LYS 147.A O no hydrogen 2.991 N/A SER 156.A OG LEU 153.A O no hydrogen 3.179 N/A PHE 160.A N HIS 158.A ND1 no hydrogen 3.207 N/A LEU 161.A N HIS 158.A O no hydrogen 2.934 N/A THR 162.A N ILE 241.A O no hydrogen 3.074 N/A THR 162.A OG1 ILE 241.A O no hydrogen 3.242 N/A LYS 165.A N VAL 177.A O no hydrogen 2.948 N/A LYS 165.A NZ TYR 141.A OH no hydrogen 2.874 N/A TYR 166.A N VAL 177.A O no hydrogen 3.435 N/A PHE 168.A N CYS 175.A O no hydrogen 3.086 N/A THR 170.A N ARG 173.A O no hydrogen 2.753 N/A ARG 173.A NH1 ASP 172.A O no hydrogen 2.595 N/A LEU 174.A N LEU 146.A O no hydrogen 2.607 N/A CYS 175.A N PHE 168.A O no hydrogen 2.684 N/A PHE 176.A N LYS 144.A O no hydrogen 2.797 N/A VAL 177.A N TYR 166.A O no hydrogen 3.154 N/A MET 178.A N ALA 142.A O no hydrogen 2.946 N/A GLU 179.A N ALA 163.A O no hydrogen 2.877 N/A ASN 182.A ND2 SER 371.A O no hydrogen 2.776 N/A ASN 182.A ND2 ASP 374.A O no hydrogen 3.520 N/A GLY 183.A N LEU 233.A O no hydrogen 2.814 N/A LEU 186.A N LEU 231.A O no hydrogen 3.173 N/A HIS 189.A N GLU 185.A O no hydrogen 3.160 N/A HIS 189.A N LEU 186.A O no hydrogen 3.018 N/A HIS 189.A NE2 GLY 183.A O no hydrogen 2.479 N/A LEU 190.A N LEU 186.A O no hydrogen 2.733 N/A SER 191.A N PHE 187.A O no hydrogen 2.825 N/A SER 191.A OG PHE 187.A O no hydrogen 2.838 N/A SER 191.A OG PHE 188.A O no hydrogen 3.531 N/A ARG 192.A NH1 GLU 193.A OE2 no hydrogen 2.739 N/A GLU 193.A N HIS 189.A O no hydrogen 2.957 N/A VAL 195.A N GLU 193.A O no hydrogen 2.522 N/A PHE 196.A N MET 282.A O no hydrogen 2.633 N/A SER 197.A OG ASP 199.A OD1 no hydrogen 2.515 N/A ARG 200.A NH1 GLU 193.A OE2 no hydrogen 3.117 N/A ARG 200.A NH2 GLU 193.A OE2 no hydrogen 3.327 N/A ALA 201.A N SER 197.A O no hydrogen 2.953 N/A ARG 202.A N GLU 198.A O no hydrogen 3.054 N/A ARG 202.A NE PHE 347.A O no hydrogen 2.823 N/A PHE 203.A N ASP 199.A O no hydrogen 3.092 N/A TYR 204.A N ARG 200.A O no hydrogen 3.149 N/A GLY 205.A N ALA 201.A O no hydrogen 2.646 N/A ALA 206.A N ARG 202.A O no hydrogen 2.727 N/A GLU 207.A N PHE 203.A O no hydrogen 3.160 N/A ILE 208.A N TYR 204.A O no hydrogen 3.175 N/A VAL 209.A N GLY 205.A O no hydrogen 2.975 N/A SER 210.A N ALA 206.A O no hydrogen 2.981 N/A SER 210.A OG HIS 158.A NE2 no hydrogen 3.402 N/A ALA 211.A N GLU 207.A O no hydrogen 3.222 N/A LEU 212.A N ILE 208.A O no hydrogen 2.831 N/A ASP 213.A N VAL 209.A O no hydrogen 2.873 N/A TYR 214.A N SER 210.A O no hydrogen 3.087 N/A LEU 215.A N ALA 211.A O no hydrogen 2.966 N/A HIS 216.A N LEU 212.A O no hydrogen 2.989 N/A HIS 216.A N ASP 213.A O no hydrogen 3.265 N/A HIS 216.A ND1 ASP 338.A OD2 no hydrogen 2.595 N/A HIS 216.A NE2 ASP 271.A OD1 no hydrogen 2.631 N/A SER 217.A N ASP 213.A O no hydrogen 2.852 N/A SER 217.A OG ASP 213.A O no hydrogen 3.075 N/A GLU 218.A N TYR 214.A O no hydrogen 3.033 N/A LYS 219.A N TYR 214.A O no hydrogen 3.247 N/A LYS 219.A NZ ASN 155.A O no hydrogen 3.548 N/A VAL 221.A N LEU 215.A O no hydrogen 2.697 N/A VAL 222.A N ASN 50.A OD1 no hydrogen 2.730 N/A TYR 223.A N ASP 271.A OD1 no hydrogen 2.906 N/A TYR 223.A OH THR 242.A O no hydrogen 2.643 N/A ARG 224.A N ASP 271.A OD2 no hydrogen 2.664 N/A ARG 224.A NH1 TYR 17.A OH no hydrogen 3.122 N/A ARG 224.A NH2 TYR 17.A OH no hydrogen 2.615 N/A GLU 229.A N GLU 229.A OE1 no hydrogen 2.537 N/A ASN 230.A N LYS 227.A O no hydrogen 3.253 N/A ASN 230.A ND2 ASP 225.A O no hydrogen 2.837 N/A ASN 230.A ND2 ASP 225.A OD2 no hydrogen 3.119 N/A LEU 231.A N LEU 228.A O no hydrogen 3.245 N/A MET 232.A N LYS 240.A O no hydrogen 2.815 N/A LEU 233.A N GLY 184.A O no hydrogen 3.432 N/A ASP 234.A N HIS 238.A O no hydrogen 2.974 N/A LYS 235.A NZ ASP 236.A OD1 no hydrogen 3.145 N/A GLY 237.A N ASP 234.A O no hydrogen 2.900 N/A GLY 237.A N ASP 234.A OD1 no hydrogen 2.799 N/A HIS 238.A N ASP 234.A OD1 no hydrogen 2.662 N/A HIS 238.A ND1 GLU 207.A OE1 no hydrogen 2.644 N/A ILE 239.A N GLU 207.A OE2 no hydrogen 2.701 N/A LYS 240.A N MET 232.A O no hydrogen 2.630 N/A LYS 240.A NZ PRO 159.A O no hydrogen 3.362 N/A LYS 240.A NZ LEU 161.A O no hydrogen 2.884 N/A LYS 240.A NZ GLU 179.A OE2 no hydrogen 3.482 N/A ILE 241.A N PHE 160.A O no hydrogen 2.734 N/A THR 242.A N ASN 230.A O no hydrogen 3.167 N/A CYS 247.A SG GLU 249.A OE2 no hydrogen 3.339 N/A LEU 256.A N PRO 253.A O no hydrogen 3.139 N/A GLU 259.A N GLU 259.A OE1 no hydrogen 2.552 N/A LEU 261.A N ALA 257.A O no hydrogen 3.074 N/A GLU 262.A N PRO 258.A O no hydrogen 3.031 N/A ASP 263.A N VAL 260.A O no hydrogen 3.164 N/A ASN 264.A N GLU 259.A O no hydrogen 3.019 N/A VAL 270.A N GLY 267.A O no hydrogen 3.246 N/A ASP 271.A N ARG 268.A O no hydrogen 2.873 N/A TRP 272.A NE1 ASP 338.A OD1 no hydrogen 2.646 N/A TRP 273.A N ALA 269.A O no hydrogen 2.981 N/A GLY 274.A N VAL 270.A O no hydrogen 2.927 N/A LEU 275.A N ASP 271.A O no hydrogen 2.713 N/A GLY 276.A N TRP 272.A O no hydrogen 2.822 N/A VAL 277.A N TRP 273.A O no hydrogen 2.947 N/A VAL 278.A N GLY 274.A O no hydrogen 3.070 N/A MET 279.A N LEU 275.A O no hydrogen 2.993 N/A TYR 280.A N GLY 276.A O no hydrogen 2.854 N/A TYR 280.A OH ARG 307.A O no hydrogen 2.852 N/A GLU 281.A N VAL 277.A O no hydrogen 3.072 N/A MET 282.A N VAL 278.A O no hydrogen 3.089 N/A MET 283.A N MET 279.A O no hydrogen 3.279 N/A CYS 284.A SG TYR 280.A O no hydrogen 3.090 N/A GLY 285.A N GLU 281.A O no hydrogen 2.768 N/A ARG 286.A NH1 PRO 288.A O no hydrogen 3.437 N/A GLN 292.A N ASN 291.A OD1 no hydrogen 2.671 N/A LEU 297.A N ASP 293.A O no hydrogen 2.518 N/A PHE 298.A N HIS 294.A O no hydrogen 2.861 N/A GLU 299.A N GLU 295.A O no hydrogen 3.171 N/A LEU 300.A N LYS 296.A O no hydrogen 2.762 N/A ILE 301.A N LEU 297.A O no hydrogen 3.220 N/A LEU 302.A N PHE 298.A O no hydrogen 2.888 N/A MET 303.A N GLU 299.A O no hydrogen 2.909 N/A GLU 304.A N GLU 299.A O no hydrogen 3.306 N/A LEU 312.A N PRO 309.A O no hydrogen 3.016 N/A LYS 317.A N GLY 313.A O no hydrogen 3.035 N/A SER 318.A N PRO 314.A O no hydrogen 3.104 N/A SER 318.A OG HIS 345.A NE2 no hydrogen 2.783 N/A LEU 319.A N GLU 315.A O no hydrogen 3.288 N/A LEU 320.A N ALA 316.A O no hydrogen 2.899 N/A SER 321.A N LYS 317.A O no hydrogen 2.928 N/A SER 321.A OG LYS 317.A O no hydrogen 2.392 N/A GLY 322.A N SER 318.A O no hydrogen 3.095 N/A LEU 323.A N LEU 319.A O no hydrogen 2.933 N/A LEU 324.A N LEU 320.A O no hydrogen 2.834 N/A LYS 329.A N ASP 327.A OD1 no hydrogen 3.379 N/A GLN 330.A N ASP 327.A O no hydrogen 2.891 N/A ARG 331.A N PRO 328.A O no hydrogen 3.382 N/A ARG 331.A NE LYS 325.A O no hydrogen 2.900 N/A ARG 331.A NH1 GLU 259.A OE2 no hydrogen 2.766 N/A ARG 331.A NH1 ALA 269.A O no hydrogen 2.972 N/A ARG 331.A NH2 GLU 259.A OE1 no hydrogen 2.961 N/A ARG 331.A NH2 GLU 259.A OE2 no hydrogen 3.440 N/A ARG 331.A NH2 LYS 325.A O no hydrogen 2.970 N/A LEU 332.A N GLY 322.A O no hydrogen 2.944 N/A GLY 333.A N GLU 341.A OE2 no hydrogen 2.852 N/A GLY 334.A N ARG 331.A O no hydrogen 2.828 N/A ASP 338.A N GLY 335.A O no hydrogen 2.990 N/A LYS 340.A N GLU 337.A O no hydrogen 3.174 N/A LYS 340.A NZ ASP 213.A OD1 no hydrogen 3.426 N/A GLU 341.A N ASP 338.A O no hydrogen 2.782 N/A ILE 342.A N ALA 339.A O no hydrogen 2.940 N/A MET 343.A N ALA 339.A O no hydrogen 2.724 N/A GLN 344.A N LYS 340.A O no hydrogen 2.992 N/A HIS 345.A N ILE 342.A O no hydrogen 3.128 N/A HIS 345.A NE2 SER 318.A OG no hydrogen 2.783 N/A PHE 347.A N HIS 345.A ND1 no hydrogen 2.982 N/A PHE 348.A N HIS 345.A O no hydrogen 3.046 N/A ALA 349.A N ARG 346.A O no hydrogen 3.232 N/A HIS 355.A N VAL 352.A O no hydrogen 3.179 N/A VAL 356.A N VAL 352.A O no hydrogen 3.320 N/A TYR 357.A N TRP 353.A O no hydrogen 3.243 N/A GLU 358.A N GLN 354.A O no hydrogen 3.178 N/A GLU 358.A N HIS 355.A O no hydrogen 3.241 N/A LYS 359.A N VAL 356.A O no hydrogen 3.092 N/A LYS 360.A N HIS 355.A O no hydrogen 2.818 N/A LYS 360.A NZ GLU 358.A OE1 no hydrogen 2.524 N/A GLN 368.A N TYR 377.A OH no hydrogen 2.919 N/A VAL 369.A N PRO 367.A O no hydrogen 2.835 N/A THR 370.A N ASP 374.A OD2 no hydrogen 3.111 N/A SER 371.A OG GLU 372.A OE1 no hydrogen 2.131 N/A ASP 374.A N SER 371.A O no hydrogen 3.186 N/A THR 375.A OG1 THR 375.A O no hydrogen 2.378 N/A THR 375.A OG1 ASP 379.A OD1 no hydrogen 3.568 N/A