Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6hu8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASP 4.A OD2 no hydrogen 3.242 N/A LYS 3.A NZ GLY 42.A O no hydrogen 3.435 N/A ASP 4.A N SER 1.A OG no hydrogen 3.215 N/A SER 5.A N SER 1.A O no hydrogen 3.012 N/A SER 5.A OG SER 1.A O no hydrogen 3.385 N/A SER 5.A OG ILE 2.A O no hydrogen 3.002 N/A SER 5.A OG ASP 69.A OD2 no hydrogen 2.541 N/A ILE 6.A N ILE 2.A O no hydrogen 2.959 N/A GLY 7.A N LYS 3.A O no hydrogen 2.893 N/A LEU 8.A N ASP 4.A O no hydrogen 2.978 N/A ARG 9.A N SER 5.A O no hydrogen 2.992 N/A ARG 9.A NH1 ASP 69.A OD2 no hydrogen 2.691 N/A ARG 9.A NH2 ASP 69.A OD2 no hydrogen 2.555 N/A ILE 10.A N ILE 6.A O no hydrogen 3.018 N/A LYS 11.A N GLY 7.A O no hydrogen 2.897 N/A LYS 11.A NZ GLU 15.A OE2 no hydrogen 3.005 N/A THR 12.A N LEU 8.A O no hydrogen 2.786 N/A THR 12.A OG1 LEU 8.A O no hydrogen 2.874 N/A GLU 13.A N ARG 9.A O no hydrogen 3.117 N/A ARG 14.A N ILE 10.A O no hydrogen 2.971 N/A ARG 14.A NE GLU 40.A OE2 no hydrogen 2.712 N/A ARG 14.A NH1 MET 19.A O no hydrogen 2.824 N/A ARG 14.A NH2 GLU 40.A OE1 no hydrogen 2.870 N/A ARG 14.A NH2 GLU 40.A OE2 no hydrogen 3.379 N/A GLU 15.A N LYS 11.A O no hydrogen 3.039 N/A CYS 16.A N THR 12.A O no hydrogen 2.843 N/A GLN 17.A N GLU 13.A O no hydrogen 3.050 N/A GLN 17.A N ARG 14.A O no hydrogen 3.115 N/A GLN 17.A NE2 GLU 13.A OE1 no hydrogen 3.023 N/A GLN 17.A NE2 LEU 58.A O no hydrogen 2.785 N/A GLN 18.A N GLU 15.A O no hydrogen 2.706 N/A MET 19.A N ARG 14.A O no hydrogen 3.040 N/A ARG 21.A NE GLU 40.A OE1 no hydrogen 3.024 N/A ARG 21.A NH2 GLU 40.A OE1 no hydrogen 2.756 N/A GLU 22.A N GLU 22.A OE1 no hydrogen 2.835 N/A VAL 23.A N SER 20.A OG no hydrogen 3.094 N/A LEU 24.A N SER 20.A O no hydrogen 3.076 N/A CYS 25.A N ARG 21.A O no hydrogen 2.925 N/A CYS 25.A SG ARG 21.A O no hydrogen 3.419 N/A LEU 26.A N VAL 23.A O no hydrogen 3.315 N/A GLY 28.A N CYS 25.A O no hydrogen 2.894 N/A ALA 29.A N ASP 27.A OD1 no hydrogen 2.915 N/A THR 32.A N GLN 35.A OE1 no hydrogen 2.883 N/A THR 32.A OG1 ASP 146.A OD2 no hydrogen 2.695 N/A ARG 34.A NE ASP 146.A OD2 no hydrogen 3.304 N/A ARG 34.A NH1 GLU 145.A OE1 no hydrogen 3.486 N/A ARG 34.A NH2 GLU 145.A OE1 no hydrogen 2.616 N/A ARG 34.A NH2 ASP 146.A OD1 no hydrogen 2.767 N/A GLN 35.A N THR 32.A OG1 no hydrogen 3.177 N/A GLN 35.A NE2 GLN 150.A OE1 no hydrogen 3.131 N/A LEU 36.A N THR 32.A O no hydrogen 2.922 N/A ILE 37.A N VAL 33.A O no hydrogen 2.866 N/A ARG 38.A N ARG 34.A O no hydrogen 3.096 N/A ARG 38.A NE GLU 116.A OE1 no hydrogen 2.597 N/A ARG 38.A NH2 GLU 116.A OE1 no hydrogen 3.494 N/A ARG 38.A NH2 GLU 116.A OE2 no hydrogen 2.818 N/A ILE 39.A N GLN 35.A O no hydrogen 3.225 N/A GLU 40.A N LEU 36.A O no hydrogen 2.904 N/A LYS 41.A N ILE 37.A O no hydrogen 2.954 N/A GLY 42.A N ILE 39.A O no hydrogen 2.966 N/A GLU 43.A N ARG 38.A O no hydrogen 2.746 N/A SER 44.A N ARG 38.A O no hydrogen 3.125 N/A SER 44.A OG GLU 116.A OE1 no hydrogen 2.858 N/A SER 47.A OG GLU 117.A OE2 no hydrogen 2.454 N/A LYS 50.A N SER 47.A OG no hydrogen 3.346 N/A LYS 50.A NZ GLU 30.A O no hydrogen 2.946 N/A LYS 50.A NZ GLN 150.A OE1 no hydrogen 3.171 N/A LEU 51.A N SER 47.A O no hydrogen 2.801 N/A SER 52.A N LEU 48.A O no hydrogen 2.806 N/A TYR 53.A N ASP 49.A O no hydrogen 3.140 N/A TYR 53.A OH LEU 24.A O no hydrogen 2.709 N/A ILE 54.A N LYS 50.A O no hydrogen 3.001 N/A ALA 55.A N LEU 51.A O no hydrogen 2.867 N/A LYS 56.A N SER 52.A O no hydrogen 3.093 N/A ARG 57.A N TYR 53.A O no hydrogen 2.929 N/A ARG 57.A NE LEU 24.A O no hydrogen 2.884 N/A ARG 57.A NH2 VAL 23.A O no hydrogen 2.890 N/A LEU 58.A N ILE 54.A O no hydrogen 3.050 N/A GLY 59.A N LYS 56.A O no hydrogen 3.259 N/A LYS 60.A N ALA 55.A O no hydrogen 2.985 N/A SER 61.A N ASP 64.A OD2 no hydrogen 3.067 N/A SER 61.A OG ASP 64.A OD1 no hydrogen 3.304 N/A ASP 64.A N SER 61.A O no hydrogen 2.891 N/A LEU 66.A N MET 62.A O no hydrogen 3.133 N/A LEU 66.A N ALA 63.A O no hydrogen 3.228 N/A ASP 67.A N ALA 63.A O no hydrogen 3.082 N/A ASP 69.A N LEU 66.A O no hydrogen 2.840 N/A ARG 70.A NH2 GLU 72.A OE2 no hydrogen 2.532 N/A TYR 77.A N PRO 74.A O no hydrogen 3.082 N/A TYR 77.A OH GLU 118.A OE1 no hydrogen 2.517 N/A GLU 79.A N ASP 75.A O no hydrogen 3.041 N/A MET 80.A N THR 76.A O no hydrogen 3.093 N/A LYS 81.A N TYR 77.A O no hydrogen 2.794 N/A LYS 81.A NZ GLU 118.A OE1 no hydrogen 2.745 N/A LYS 81.A NZ GLU 118.A OE2 no hydrogen 3.081 N/A LYS 81.A NZ ASN 160.A OD1 no hydrogen 2.574 N/A ASN 82.A N TYR 78.A O no hydrogen 2.832 N/A ARG 83.A N GLU 79.A O no hydrogen 2.937 N/A LEU 84.A N MET 80.A O no hydrogen 2.885 N/A ILE 85.A N LYS 81.A O no hydrogen 2.947 N/A LYS 86.A N ASN 82.A O no hydrogen 3.147 N/A PHE 87.A N LEU 84.A O no hydrogen 3.268 N/A ASP 92.A N THR 89.A O no hydrogen 2.842 N/A GLU 94.A N ASP 92.A OD1 no hydrogen 2.780 N/A ARG 95.A N ASP 92.A OD1 no hydrogen 2.911 N/A ARG 95.A NE PRO 88.A O no hydrogen 2.657 N/A ARG 95.A NH2 PRO 88.A O no hydrogen 3.028 N/A VAL 96.A N ASP 92.A O no hydrogen 2.925 N/A LYS 97.A N LYS 93.A O no hydrogen 3.242 N/A LYS 97.A NZ ASP 101.A OD2 no hydrogen 2.410 N/A GLN 98.A N GLU 94.A O no hydrogen 3.174 N/A GLN 98.A NE2 GLU 94.A O no hydrogen 2.876 N/A LYS 99.A N ARG 95.A O no hydrogen 2.866 N/A LYS 99.A NZ PHE 87.A O no hydrogen 2.676 N/A LEU 100.A N VAL 96.A O no hydrogen 2.965 N/A ASP 101.A N LYS 97.A O no hydrogen 2.933 N/A LEU 102.A N GLN 98.A O no hydrogen 3.057 N/A ILE 103.A N LYS 99.A O no hydrogen 3.040 N/A GLU 104.A N LEU 100.A O no hydrogen 2.973 N/A ASP 105.A N ASP 101.A O no hydrogen 2.981 N/A VAL 106.A N LEU 102.A O no hydrogen 2.922 N/A TYR 107.A N ILE 103.A O no hydrogen 2.933 N/A ASN 108.A N GLU 104.A O no hydrogen 2.926 N/A GLN 109.A N ASP 105.A O no hydrogen 2.992 N/A GLN 109.A NE2 ASP 105.A OD1 no hydrogen 2.813 N/A PHE 110.A N TYR 107.A O no hydrogen 3.245 N/A PHE 111.A N TYR 107.A O no hydrogen 2.824 N/A ILE 113.A N PHE 110.A O no hydrogen 2.921 N/A GLU 117.A N GLU 117.A OE1 no hydrogen 2.640 N/A LEU 119.A N PRO 115.A O no hydrogen 3.137 N/A LEU 120.A N GLU 116.A O no hydrogen 2.862 N/A THR 121.A N GLU 117.A O no hydrogen 3.154 N/A THR 121.A OG1 GLU 117.A O no hydrogen 3.378 N/A THR 121.A OG1 ASN 160.A OD1 no hydrogen 2.982 N/A LEU 122.A N GLU 118.A O no hydrogen 3.203 N/A ASP 123.A N LEU 119.A O no hydrogen 3.113 N/A ILE 124.A N LEU 120.A O no hydrogen 2.793 N/A LEU 125.A N THR 121.A O no hydrogen 3.156 N/A GLU 126.A N LEU 122.A O no hydrogen 3.059 N/A ASN 127.A N ASP 123.A O no hydrogen 2.783 N/A ASN 127.A ND2 TYR 167.A OH no hydrogen 2.818 N/A ILE 128.A N ILE 124.A O no hydrogen 2.996 N/A LEU 129.A N LEU 125.A O no hydrogen 2.968 N/A SER 130.A N GLU 126.A O no hydrogen 3.029 N/A SER 130.A N ASN 127.A O no hydrogen 3.286 N/A SER 130.A OG GLU 126.A O no hydrogen 2.838 N/A SER 130.A OG ASN 127.A O no hydrogen 3.277 N/A SER 130.A OG THR 132.A OG1 no hydrogen 2.701 N/A PHE 131.A N ILE 128.A O no hydrogen 3.031 N/A THR 132.A N ASN 127.A O no hydrogen 2.941 N/A THR 132.A OG1 SER 130.A OG no hydrogen 2.701 N/A SER 133.A OG GLU 135.A OE1 no hydrogen 2.784 N/A GLU 135.A N SER 133.A OG no hydrogen 3.155 N/A GLU 135.A N GLU 135.A OE1 no hydrogen 3.044 N/A GLU 136.A N SER 133.A O no hydrogen 3.028 N/A ARG 137.A N TRP 134.A O no hydrogen 3.379 N/A ARG 137.A NE ASN 127.A OD1 no hydrogen 3.063 N/A ARG 137.A NH2 ASP 123.A OD1 no hydrogen 3.165 N/A ARG 137.A NH2 ASN 127.A OD1 no hydrogen 3.053 N/A GLU 141.A N ARG 137.A O no hydrogen 2.833 N/A GLU 142.A N PRO 138.A O no hydrogen 2.911 N/A ILE 143.A N LYS 139.A O no hydrogen 3.476 N/A TYR 144.A N VAL 140.A O no hydrogen 2.803 N/A GLU 145.A N GLU 141.A O no hydrogen 2.836 N/A LEU 147.A N ILE 143.A O no hydrogen 3.235 N/A PHE 148.A N TYR 144.A O no hydrogen 2.799 N/A GLU 149.A N GLU 145.A O no hydrogen 3.070 N/A GLN 150.A N ASP 146.A O no hydrogen 3.076 N/A GLN 150.A NE2 GLY 28.A O no hydrogen 2.957 N/A GLN 150.A NE2 GLN 35.A OE1 no hydrogen 3.082 N/A VAL 151.A N LEU 147.A O no hydrogen 2.963 N/A LYS 152.A N PHE 148.A O no hydrogen 3.038 N/A LYS 152.A NZ GLU 149.A OE2 no hydrogen 2.562 N/A ARG 153.A N GLN 150.A O no hydrogen 3.195 N/A ARG 153.A NH1 ASP 27.A OD2 no hydrogen 2.994 N/A LYS 154.A N VAL 151.A O no hydrogen 2.962 N/A LYS 154.A NZ ASP 161.A OD1 no hydrogen 2.666 N/A LYS 154.A NZ ASP 161.A OD2 no hydrogen 3.028 N/A PHE 157.A N GLN 193.A OE1 no hydrogen 2.855 N/A SER 158.A N ASP 161.A OD2 no hydrogen 2.911 N/A ASN 160.A ND2 GLU 118.A OE2 no hydrogen 2.766 N/A ASP 161.A N SER 158.A OG no hydrogen 3.115 N/A LEU 162.A N SER 158.A O no hydrogen 2.866 N/A LEU 163.A N THR 159.A O no hydrogen 3.000 N/A VAL 164.A N ASN 160.A O no hydrogen 2.959 N/A ILE 165.A N ASP 161.A O no hydrogen 2.899 N/A ASP 166.A N LEU 162.A O no hydrogen 2.890 N/A TYR 167.A N LEU 163.A O no hydrogen 3.013 N/A TYR 168.A N VAL 164.A O no hydrogen 2.922 N/A PHE 169.A N ILE 165.A O no hydrogen 3.067 N/A TYR 170.A N ASP 166.A O no hydrogen 2.900 N/A TYR 170.A OH THR 132.A O no hydrogen 2.719 N/A HIS 171.A N TYR 167.A O no hydrogen 3.081 N/A HIS 171.A N TYR 168.A O no hydrogen 2.829 N/A HIS 171.A ND1 TYR 167.A O no hydrogen 2.687 N/A HIS 171.A NE2 GLU 141.A OE1 no hydrogen 3.148 N/A HIS 171.A NE2 GLU 141.A OE2 no hydrogen 2.856 N/A LEU 172.A N PHE 169.A O no hydrogen 2.876 N/A ARG 175.A N LEU 172.A O no hydrogen 3.037 N/A LYS 180.A NZ ASP 184.A OD2 no hydrogen 3.299 N/A ILE 182.A N ASP 179.A OD1 no hydrogen 3.207 N/A PHE 183.A N ASP 179.A O no hydrogen 3.152 N/A ASP 184.A N LYS 180.A O no hydrogen 3.056 N/A ARG 185.A N LYS 181.A O no hydrogen 3.064 N/A ILE 186.A N ILE 182.A O no hydrogen 2.889 N/A VAL 187.A N PHE 183.A O no hydrogen 2.843 N/A ASP 188.A N ASP 184.A O no hydrogen 2.949 N/A ARG 189.A N ARG 185.A O no hydrogen 3.107 N/A VAL 190.A N ILE 186.A O no hydrogen 2.805 N/A LEU 191.A N VAL 187.A O no hydrogen 2.914 N/A LYS 192.A N ARG 189.A O no hydrogen 3.200 N/A GLN 193.A N VAL 190.A O no hydrogen 3.214 N/A GLN 193.A NE2 LYS 155.A O no hydrogen 2.893 N/A GLN 193.A NE2 ARG 189.A O no hydrogen 2.832 N/A TYR 201.A N ASP 198.A OD1 no hydrogen 3.440 N/A TYR 201.A OH PHE 157.A O no hydrogen 2.914 N/A ASN 202.A N ASP 198.A O no hydrogen 2.894 N/A ASN 202.A ND2 PRO 196.A O no hydrogen 2.958 N/A ASN 202.A ND2 SER 239.A OG no hydrogen 2.671 N/A ILE 203.A N ASP 199.A O no hydrogen 2.710 N/A ALA 204.A N ALA 200.A O no hydrogen 3.179 N/A LEU 205.A N TYR 201.A O no hydrogen 2.830 N/A PHE 206.A N ASN 202.A O no hydrogen 2.708 N/A ASN 207.A N ILE 203.A O no hydrogen 2.930 N/A ASP 208.A N ALA 204.A O no hydrogen 3.039 N/A LEU 209.A N LEU 205.A O no hydrogen 2.897 N/A MET 210.A N PHE 206.A O no hydrogen 2.825 N/A ALA 211.A N ASN 207.A O no hydrogen 3.054 N/A ILE 212.A N ASP 208.A O no hydrogen 3.014 N/A ALA 213.A N LEU 209.A O no hydrogen 3.053 N/A GLY 214.A N MET 210.A O no hydrogen 3.031 N/A LEU 215.A N ALA 211.A O no hydrogen 2.935 N/A LYS 216.A N ILE 212.A O no hydrogen 2.691 N/A LYS 216.A NZ SER 221.A O no hydrogen 2.847 N/A LYS 216.A NZ LYS 223.A O no hydrogen 3.038 N/A ILE 217.A N ALA 213.A O no hydrogen 3.234 N/A SER 218.A N GLY 214.A O no hydrogen 3.071 N/A SER 218.A OG GLY 214.A O no hydrogen 3.265 N/A SER 218.A OG LEU 215.A O no hydrogen 3.241 N/A LEU 219.A N LEU 215.A O no hydrogen 2.594 N/A GLU 220.A N ILE 217.A O no hydrogen 3.388 N/A SER 221.A N LYS 216.A O no hydrogen 2.811 N/A LYS 223.A NZ ASP 184.A OD2 no hydrogen 3.262 N/A PHE 225.A N PHE 222.A O no hydrogen 3.131 N/A VAL 228.A N ASP 224.A O no hydrogen 3.038 N/A ILE 229.A N PHE 225.A O no hydrogen 3.046 N/A ASP 230.A N LEU 226.A O no hydrogen 2.885 N/A LYS 231.A N THR 227.A O no hydrogen 3.054 N/A LYS 231.A NZ LEU 191.A O no hydrogen 2.321 N/A LYS 231.A NZ GLN 193.A O no hydrogen 2.854 N/A LEU 232.A N VAL 228.A O no hydrogen 3.014 N/A LEU 233.A N ILE 229.A O no hydrogen 3.025 N/A ALA 234.A N ASP 230.A O no hydrogen 2.912 N/A VAL 235.A N LYS 231.A O no hydrogen 2.858 N/A ILE 236.A N LEU 232.A O no hydrogen 3.069 N/A GLU 237.A N LEU 233.A O no hydrogen 2.877 N/A LYS 238.A N ALA 234.A O no hydrogen 3.042 N/A LYS 238.A NZ ILE 195.A O no hydrogen 2.767 N/A SER 239.A N VAL 235.A O no hydrogen 3.097 N/A SER 239.A OG ASP 199.A OD1 no hydrogen 2.976 N/A GLN 240.A NE2 GLU 237.A O no hydrogen 2.878 N/A GLN 240.A NE2 GLU 237.A OE2 no hydrogen 3.189 N/A PHE 241.A N ILE 236.A O no hydrogen 3.074 N/A HIS 242.A N GLN 240.A O no hydrogen 2.973 N/A HIS 242.A NE2 GLN 240.A OE1 no hydrogen 2.819 N/A TYR 244.A N PHE 241.A O no hydrogen 3.098 N/A LYS 245.A N HIS 242.A O no hydrogen 3.403 N/A VAL 248.A N LYS 245.A O no hydrogen 3.032 N/A TYR 249.A N LYS 245.A O no hydrogen 3.116 N/A ILE 250.A N PRO 246.A O no hydrogen 2.957 N/A LEU 251.A N GLY 247.A O no hydrogen 3.332 N/A GLU 252.A N VAL 248.A O no hydrogen 3.081 N/A ALA 253.A N TYR 249.A O no hydrogen 2.945 N/A LYS 254.A N ILE 250.A O no hydrogen 2.958 N/A LYS 254.A NZ TYR 270.A OH no hydrogen 3.287 N/A LYS 254.A NZ GLU 292.A OE2 no hydrogen 2.596 N/A LYS 254.A NZ ASP 296.A OD2 no hydrogen 2.888 N/A TYR 255.A N LEU 251.A O no hydrogen 2.965 N/A GLU 256.A N GLU 252.A O no hydrogen 3.058 N/A LEU 257.A N ALA 253.A O no hydrogen 2.924 N/A ILE 258.A N LYS 254.A O no hydrogen 2.806 N/A HIS 259.A N TYR 255.A O no hydrogen 2.724 N/A ASN 260.A N GLU 256.A O no hydrogen 3.172 N/A ASN 260.A ND2 GLU 256.A OE2 no hydrogen 3.171 N/A ASN 262.A N GLU 256.A O no hydrogen 2.904 N/A LYS 264.A NZ GLU 268.A OE2 no hydrogen 2.625 N/A LYS 265.A N ASN 262.A OD1 no hydrogen 3.067 N/A ALA 266.A N ASN 262.A O no hydrogen 2.997 N/A THR 267.A N LYS 263.A O no hydrogen 2.862 N/A THR 267.A OG1 LYS 263.A O no hydrogen 2.650 N/A GLU 268.A N LYS 264.A O no hydrogen 2.980 N/A ASN 269.A N LYS 265.A O no hydrogen 3.003 N/A TYR 270.A N ALA 266.A O no hydrogen 2.930 N/A TYR 270.A OH ASP 296.A OD2 no hydrogen 2.541 N/A ASP 271.A N THR 267.A O no hydrogen 2.912 N/A LYS 272.A N GLU 268.A O no hydrogen 2.916 N/A ALA 273.A N ASN 269.A O no hydrogen 3.045 N/A ILE 274.A N TYR 270.A O no hydrogen 2.858 N/A MET 275.A N ASP 271.A O no hydrogen 2.837 N/A PHE 276.A N LYS 272.A O no hydrogen 2.920 N/A ALA 277.A N ALA 273.A O no hydrogen 2.929 N/A SER 278.A N ILE 274.A O no hydrogen 2.845 N/A SER 278.A N MET 275.A O no hydrogen 3.135 N/A SER 278.A OG MET 275.A O no hydrogen 2.709 N/A LEU 280.A N ALA 277.A O no hydrogen 3.085 N/A SER 283.A OG GLU 287.A OE2 no hydrogen 2.866 N/A VAL 284.A N ASP 282.A OD1 no hydrogen 3.078 N/A GLU 287.A N SER 283.A O no hydrogen 2.947 N/A LYS 288.A N VAL 284.A O no hydrogen 2.891 N/A THR 289.A N LEU 285.A O no hydrogen 2.753 N/A THR 289.A OG1 LEU 285.A O no hydrogen 2.827 N/A ARG 290.A N GLU 286.A O no hydrogen 2.906 N/A ARG 290.A NH2 GLU 286.A OE2 no hydrogen 2.768 N/A ALA 291.A N GLU 287.A O no hydrogen 2.910 N/A GLU 292.A N LYS 288.A O no hydrogen 2.964 N/A LYS 293.A N THR 289.A O no hydrogen 3.007 N/A LYS 293.A NZ ASP 271.A OD1 no hydrogen 2.666 N/A ALA 294.A N ARG 290.A O no hydrogen 3.191 N/A ALA 295.A N ALA 291.A O no hydrogen 2.965 N/A ASP 296.A N GLU 292.A O no hydrogen 3.025 N/A GLY 297.A N ALA 294.A O no hydrogen 3.027 N/A LEU 298.A N LYS 293.A O no hydrogen 3.212 N/A