Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6hwu_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A NH2 PRO 88.A O no hydrogen 2.956 N/A TYR 5.A N VAL 16.A O no hydrogen 2.951 N/A TYR 5.A OH TYR 20.A O no hydrogen 2.845 N/A GLN 7.A N TRP 14.A O no hydrogen 2.856 N/A LEU 9.A N THR 12.A O no hydrogen 2.764 N/A THR 12.A N LEU 9.A O no hydrogen 2.797 N/A TRP 14.A N GLN 7.A O no hydrogen 2.730 N/A GLU 15.A N TYR 99.A OH no hydrogen 3.047 N/A VAL 16.A N TYR 5.A O no hydrogen 3.093 N/A GLU 18.A N THR 3.A O no hydrogen 2.932 N/A ARG 19.A NE ASP 39.A OD1 no hydrogen 2.969 N/A ARG 19.A NH2 ASP 39.A OD1 no hydrogen 3.185 N/A ARG 19.A NH2 ASP 39.A OD2 no hydrogen 2.798 N/A TYR 20.A N PRO 17.A O no hydrogen 3.170 N/A TYR 20.A OH ASP 84.A OD2 no hydrogen 2.655 N/A GLN 21.A N PHE 38.A O no hydrogen 2.911 N/A GLN 21.A NE2 GLU 18.A O no hydrogen 2.605 N/A SER 24.A N ALA 36.A O no hydrogen 2.853 N/A SER 24.A OG ASN 22.A O no hydrogen 3.295 N/A VAL 26.A N VAL 34.A O no hydrogen 3.054 N/A VAL 34.A N GLY 27.A O no hydrogen 3.306 N/A CYS 35.A N VAL 48.A O no hydrogen 2.866 N/A ALA 36.A N SER 24.A O no hydrogen 2.738 N/A ALA 37.A N VAL 46.A O no hydrogen 2.875 N/A PHE 38.A N GLN 21.A O no hydrogen 2.802 N/A ASP 39.A N LEU 44.A O no hydrogen 2.802 N/A THR 40.A N ARG 19.A O no hydrogen 2.884 N/A THR 40.A OG1 ARG 19.A O no hydrogen 2.850 N/A LYS 41.A N ASP 39.A OD1 no hydrogen 3.201 N/A THR 42.A OG1 ASP 39.A OD2 no hydrogen 2.641 N/A GLY 43.A N ASP 39.A O no hydrogen 2.776 N/A LEU 44.A N THR 42.A OG1 no hydrogen 3.274 N/A VAL 46.A N ALA 37.A O no hydrogen 2.852 N/A ALA 47.A N THR 102.A O no hydrogen 2.835 N/A VAL 48.A N CYS 35.A O no hydrogen 2.841 N/A LYS 49.A N LEU 100.A O no hydrogen 2.794 N/A LYS 49.A NZ GLU 67.A OE2 no hydrogen 2.926 N/A LYS 50.A N SER 33.A O no hydrogen 2.710 N/A LYS 50.A NZ ILE 13.A O no hydrogen 2.938 N/A LEU 51.A N VAL 98.A O no hydrogen 3.043 N/A SER 52.A N TYR 31.A O no hydrogen 2.735 N/A ARG 53.A NE GLN 56.A OE1 no hydrogen 2.639 N/A GLN 56.A N ARG 53.A O no hydrogen 3.423 N/A HIS 60.A N SER 57.A OG no hydrogen 3.268 N/A HIS 60.A ND1 ARG 53.A O no hydrogen 2.757 N/A ALA 61.A N SER 57.A O no hydrogen 2.878 N/A LYS 62.A N ILE 58.A O no hydrogen 2.887 N/A LYS 62.A NZ GLU 308.A O no hydrogen 2.569 N/A LYS 62.A NZ ARG 310.A O no hydrogen 3.105 N/A ARG 63.A N ILE 59.A O no hydrogen 2.889 N/A THR 64.A N HIS 60.A O no hydrogen 2.827 N/A THR 64.A OG1 PRO 54.A O no hydrogen 2.841 N/A THR 64.A OG1 HIS 60.A O no hydrogen 3.039 N/A TYR 65.A N ALA 61.A O no hydrogen 2.916 N/A ARG 66.A N LYS 62.A O no hydrogen 2.717 N/A ARG 66.A NE GLU 308.A OE1 no hydrogen 3.144 N/A ARG 66.A NE GLU 308.A OE2 no hydrogen 2.638 N/A ARG 66.A NH2 GLU 308.A OE1 no hydrogen 2.629 N/A GLU 67.A N ARG 63.A O no hydrogen 2.876 N/A LEU 68.A N THR 64.A O no hydrogen 3.089 N/A ARG 69.A N TYR 65.A O no hydrogen 2.911 N/A ARG 69.A NH1 TYR 65.A OH no hydrogen 3.060 N/A ARG 69.A NH2 ASP 304.A O no hydrogen 2.952 N/A LEU 70.A N ARG 66.A O no hydrogen 2.932 N/A LEU 71.A N GLU 67.A O no hydrogen 3.022 N/A LYS 72.A N LEU 68.A O no hydrogen 3.037 N/A LYS 72.A NZ GLU 324.A O no hydrogen 2.699 N/A LYS 72.A NZ GLU 324.A OE1 no hydrogen 2.730 N/A HIS 73.A N ARG 69.A O no hydrogen 3.227 N/A HIS 73.A N LEU 70.A O no hydrogen 2.974 N/A HIS 73.A NE2 ASP 301.A O no hydrogen 2.700 N/A MET 74.A N LEU 70.A O no hydrogen 3.173 N/A LYS 75.A N TYR 131.A OH no hydrogen 2.865 N/A GLU 77.A N GLU 77.A OE1 no hydrogen 2.726 N/A ASN 78.A N HIS 76.A ND1 no hydrogen 3.022 N/A ASN 78.A ND2 LEU 155.A O no hydrogen 3.174 N/A VAL 79.A N HIS 76.A O no hydrogen 3.278 N/A ILE 80.A N ILE 157.A O no hydrogen 3.016 N/A LEU 83.A N VAL 101.A O no hydrogen 2.887 N/A ASP 84.A N VAL 101.A O no hydrogen 3.370 N/A PHE 86.A N TYR 99.A O no hydrogen 3.103 N/A THR 87.A OG1 ASP 97.A O no hydrogen 2.869 N/A ALA 89.A N THR 87.A OG1 no hydrogen 3.170 N/A ARG 90.A N GLU 94.A OE2 no hydrogen 3.155 N/A GLU 94.A N SER 91.A O no hydrogen 3.304 N/A PHE 95.A N LEU 92.A O no hydrogen 3.100 N/A TYR 99.A N PHE 86.A O no hydrogen 3.052 N/A LEU 100.A N LYS 49.A O no hydrogen 2.907 N/A VAL 101.A N ASP 84.A O no hydrogen 2.899 N/A THR 102.A N ALA 47.A O no hydrogen 3.065 N/A THR 102.A OG1 GLY 81.A O no hydrogen 2.629 N/A LEU 104.A N ARG 45.A O no hydrogen 3.075 N/A ASP 108.A N ASN 111.A OD1 no hydrogen 3.123 N/A LEU 109.A N PRO 144.A O no hydrogen 3.189 N/A ASN 110.A N ASP 108.A OD1 no hydrogen 3.102 N/A ASN 111.A N ASP 108.A O no hydrogen 2.934 N/A ASN 111.A N ASP 108.A OD1 no hydrogen 3.399 N/A THR 114.A OG1 HIS 117.A ND1 no hydrogen 2.556 N/A HIS 117.A ND1 THR 114.A OG1 no hydrogen 2.556 N/A VAL 118.A N THR 114.A O no hydrogen 3.036 N/A GLN 119.A N ASP 115.A O no hydrogen 2.971 N/A GLN 119.A NE2 ASP 115.A OD2 no hydrogen 2.645 N/A PHE 120.A N ASP 116.A O no hydrogen 2.998 N/A LEU 121.A N HIS 117.A O no hydrogen 2.857 N/A ILE 122.A N VAL 118.A O no hydrogen 2.889 N/A TYR 123.A N GLN 119.A O no hydrogen 2.861 N/A TYR 123.A OH GLU 297.A OE2 no hydrogen 2.857 N/A GLN 124.A N PHE 120.A O no hydrogen 3.100 N/A GLN 124.A NE2 PHE 120.A O no hydrogen 3.143 N/A GLN 124.A NE2 CYS 153.A O no hydrogen 2.857 N/A ILE 125.A N LEU 121.A O no hydrogen 3.123 N/A LEU 126.A N ILE 122.A O no hydrogen 2.973 N/A ARG 127.A N TYR 123.A O no hydrogen 2.897 N/A ARG 127.A NE ASP 296.A O no hydrogen 2.919 N/A ARG 127.A NH1 ASN 78.A OD1 no hydrogen 2.862 N/A ARG 127.A NH2 GLU 77.A OE2 no hydrogen 3.381 N/A ARG 127.A NH2 ASP 296.A O no hydrogen 3.110 N/A ARG 127.A NH2 ASP 296.A OD1 no hydrogen 3.200 N/A GLY 128.A N GLN 124.A O no hydrogen 2.962 N/A LEU 129.A N ILE 125.A O no hydrogen 2.722 N/A LYS 130.A N LEU 126.A O no hydrogen 2.762 N/A LYS 130.A NZ GLU 297.A O no hydrogen 2.640 N/A TYR 131.A N ARG 127.A O no hydrogen 3.336 N/A TYR 131.A OH HIS 73.A O no hydrogen 3.227 N/A ILE 132.A N GLY 128.A O no hydrogen 2.984 N/A HIS 133.A N LEU 129.A O no hydrogen 2.808 N/A HIS 133.A NE2 ASP 185.A OD2 no hydrogen 2.717 N/A SER 134.A N LYS 130.A O no hydrogen 2.953 N/A SER 134.A OG LYS 130.A O no hydrogen 3.457 N/A SER 134.A OG TYR 131.A O no hydrogen 2.639 N/A ALA 135.A N ILE 132.A O no hydrogen 2.969 N/A ASP 136.A N HIS 133.A O no hydrogen 2.896 N/A ILE 137.A N ILE 132.A O no hydrogen 3.382 N/A HIS 139.A N ASP 185.A OD2 no hydrogen 2.954 N/A HIS 139.A NE2 LEU 158.A O no hydrogen 2.750 N/A ARG 140.A N ASP 185.A OD1 no hydrogen 2.970 N/A ASP 141.A N HIS 139.A ND1 no hydrogen 3.027 N/A LYS 143.A NZ THR 165.A OG1 no hydrogen 2.596 N/A ASN 146.A N LYS 143.A O no hydrogen 2.843 N/A ASN 146.A ND2 ASP 141.A O no hydrogen 2.954 N/A LEU 147.A N PRO 144.A O no hydrogen 3.164 N/A ALA 148.A N LYS 156.A O no hydrogen 2.929 N/A VAL 149.A N ALA 107.A O no hydrogen 3.052 N/A ASN 150.A N GLU 154.A O no hydrogen 2.752 N/A ASN 150.A ND2 GLU 154.A OE1 no hydrogen 2.803 N/A CYS 153.A N ASN 150.A O no hydrogen 3.363 N/A LEU 155.A N GLN 124.A OE1 no hydrogen 2.926 N/A LYS 156.A N ALA 148.A O no hydrogen 2.860 N/A LYS 156.A NZ GLU 77.A O no hydrogen 2.708 N/A ILE 157.A N ASN 78.A O no hydrogen 2.754 N/A LEU 158.A N ASN 146.A O no hydrogen 2.808 N/A THR 165.A OG1 ASP 141.A OD1 no hydrogen 3.486 N/A ARG 166.A NH1 GLY 205.A O no hydrogen 3.083 N/A TRP 167.A N ALA 164.A O no hydrogen 3.276 N/A TRP 167.A NE1 GLY 205.A O no hydrogen 2.963 N/A TYR 168.A N THR 165.A O no hydrogen 3.291 N/A TYR 168.A OH GLU 195.A OE1 no hydrogen 2.548 N/A TYR 168.A OH GLU 195.A OE2 no hydrogen 3.348 N/A ARG 169.A N ARG 166.A O no hydrogen 3.215 N/A ARG 169.A NH1 ARG 140.A O no hydrogen 3.159 N/A GLU 172.A N GLU 172.A OE1 no hydrogen 2.654 N/A ILE 173.A N ALA 170.A O no hydrogen 3.138 N/A LEU 175.A N PRO 171.A O no hydrogen 3.115 N/A ASN 176.A N ILE 173.A O no hydrogen 2.850 N/A TRP 177.A N GLU 172.A O no hydrogen 2.976 N/A TYR 180.A OH ILE 173.A O no hydrogen 3.427 N/A THR 183.A OG1 ASN 181.A OD1 no hydrogen 2.164 N/A THR 183.A OG1 SER 273.A O no hydrogen 2.964 N/A VAL 184.A N ASN 181.A O no hydrogen 3.116 N/A ASP 185.A N GLN 182.A O no hydrogen 3.076 N/A TRP 187.A N THR 183.A O no hydrogen 3.121 N/A SER 188.A N VAL 184.A O no hydrogen 3.343 N/A SER 188.A OG TYR 168.A O no hydrogen 2.643 N/A SER 188.A OG VAL 184.A O no hydrogen 3.311 N/A VAL 189.A N ASP 185.A O no hydrogen 2.871 N/A GLY 190.A N ILE 186.A O no hydrogen 2.885 N/A CYS 191.A N TRP 187.A O no hydrogen 3.033 N/A CYS 191.A SG TRP 167.A O no hydrogen 3.908 N/A CYS 191.A SG TRP 187.A O no hydrogen 3.548 N/A ILE 192.A N SER 188.A O no hydrogen 2.918 N/A MET 193.A N VAL 189.A O no hydrogen 2.796 N/A ALA 194.A N GLY 190.A O no hydrogen 2.939 N/A GLU 195.A N CYS 191.A O no hydrogen 3.122 N/A LEU 196.A N ILE 192.A O no hydrogen 3.000 N/A LEU 197.A N MET 193.A O no hydrogen 3.036 N/A LEU 197.A N ALA 194.A O no hydrogen 3.213 N/A THR 198.A N ALA 194.A O no hydrogen 2.934 N/A THR 198.A OG1 ALA 194.A O no hydrogen 3.012 N/A GLY 199.A N GLU 195.A O no hydrogen 2.673 N/A ARG 200.A N THR 198.A OG1 no hydrogen 3.095 N/A THR 201.A OG1 GLU 195.A OE2 no hydrogen 3.538 N/A GLY 205.A N GLN 211.A OE1 no hydrogen 3.144 N/A THR 206.A N ASP 210.A OD2 no hydrogen 2.718 N/A THR 206.A OG1 ASP 207.A OD2 no hydrogen 3.054 N/A THR 206.A OG1 ASP 210.A OD2 no hydrogen 3.327 N/A ASP 210.A N ASP 207.A OD1 no hydrogen 2.984 N/A GLN 211.A N ASP 207.A O no hydrogen 2.824 N/A GLN 211.A NE2 TRP 167.A O no hydrogen 3.234 N/A GLN 211.A NE2 PHE 203.A O no hydrogen 3.061 N/A LEU 212.A N HIS 208.A O no hydrogen 2.980 N/A LYS 213.A N ILE 209.A O no hydrogen 2.925 N/A LYS 213.A NZ ASP 210.A OD1 no hydrogen 3.151 N/A LEU 214.A N ASP 210.A O no hydrogen 2.995 N/A ILE 215.A N GLN 211.A O no hydrogen 2.955 N/A LEU 216.A N LEU 212.A O no hydrogen 2.918 N/A ARG 217.A N LYS 213.A O no hydrogen 3.278 N/A LEU 218.A N ILE 215.A O no hydrogen 2.995 N/A VAL 219.A N ILE 215.A O no hydrogen 3.039 N/A GLY 220.A N LEU 216.A O no hydrogen 2.767 N/A THR 221.A N MET 245.A O no hydrogen 3.201 N/A THR 221.A OG1 MET 245.A O no hydrogen 3.555 N/A LEU 226.A N GLY 223.A O no hydrogen 3.163 N/A LEU 227.A N GLY 223.A O no hydrogen 2.949 N/A LYS 228.A N ALA 224.A O no hydrogen 3.212 N/A LYS 229.A N LEU 226.A O no hydrogen 3.017 N/A LYS 229.A NZ ASP 272.A OD1 no hydrogen 2.898 N/A LYS 229.A NZ ASP 272.A OD2 no hydrogen 2.747 N/A LYS 229.A NZ ASP 274.A OD2 no hydrogen 2.646 N/A ILE 230.A N LEU 227.A O no hydrogen 3.098 N/A SER 234.A OG SER 232.A OG no hydrogen 2.953 N/A ALA 235.A N SER 232.A OG no hydrogen 2.913 N/A ARG 236.A N SER 232.A O no hydrogen 2.921 N/A ARG 236.A NE ILE 230.A O no hydrogen 2.895 N/A ARG 236.A NH1 GLU 233.A OE1 no hydrogen 3.098 N/A ARG 236.A NH2 ILE 230.A O no hydrogen 3.363 N/A ASN 237.A N GLU 233.A O no hydrogen 2.978 N/A ASN 237.A ND2 GLU 233.A OE2 no hydrogen 3.436 N/A TYR 238.A N SER 234.A O no hydrogen 2.990 N/A ILE 239.A N ALA 235.A O no hydrogen 3.051 N/A GLN 240.A N ARG 236.A O no hydrogen 2.989 N/A SER 241.A N ASN 237.A O no hydrogen 2.884 N/A SER 241.A OG ASN 237.A O no hydrogen 3.046 N/A SER 241.A OG TYR 238.A O no hydrogen 2.684 N/A LEU 242.A N ILE 239.A O no hydrogen 3.150 N/A MET 245.A N THR 221.A OG1 no hydrogen 3.276 N/A MET 248.A N LEU 218.A O no hydrogen 3.025 N/A ALA 251.A N ASN 249.A OD1 no hydrogen 2.914 N/A VAL 253.A N ASN 249.A O no hydrogen 3.360 N/A PHE 254.A N PHE 250.A O no hydrogen 2.733 N/A ALA 257.A N PHE 254.A O no hydrogen 3.285 N/A ASN 258.A ND2 ASP 115.A OD2 no hydrogen 3.012 N/A LEU 260.A N ASN 258.A OD1 no hydrogen 2.871 N/A VAL 262.A N ASN 258.A O no hydrogen 2.979 N/A ASP 263.A N PRO 259.A O no hydrogen 3.005 N/A LEU 264.A N LEU 260.A O no hydrogen 3.004 N/A LEU 265.A N ALA 261.A O no hydrogen 3.034 N/A GLU 266.A N VAL 262.A O no hydrogen 3.048 N/A LYS 267.A N ASP 263.A O no hydrogen 3.185 N/A LYS 267.A NZ ASP 263.A OD1 no hydrogen 3.181 N/A LYS 267.A NZ ASP 263.A OD2 no hydrogen 2.905 N/A MET 268.A N LEU 264.A O no hydrogen 2.968 N/A MET 268.A N LEU 265.A O no hydrogen 3.058 N/A LEU 269.A N LEU 265.A O no hydrogen 2.815 N/A SER 273.A OG ASN 181.A OD1 no hydrogen 3.356 N/A ASP 274.A N ASP 272.A OD1 no hydrogen 3.193 N/A LYS 275.A N ASP 272.A O no hydrogen 2.823 N/A LYS 275.A NZ GLU 225.A OE2 no hydrogen 2.751 N/A ARG 276.A N SER 273.A O no hydrogen 3.399 N/A ARG 276.A NE VAL 270.A O no hydrogen 2.639 N/A ARG 276.A NH1 GLU 172.A OE2 no hydrogen 2.642 N/A ARG 276.A NH1 THR 183.A O no hydrogen 3.112 N/A ARG 276.A NH2 GLU 172.A OE1 no hydrogen 2.741 N/A ARG 276.A NH2 VAL 270.A O no hydrogen 3.404 N/A ARG 276.A NH2 LEU 271.A O no hydrogen 2.863 N/A ILE 277.A N LYS 267.A O no hydrogen 2.984 N/A THR 278.A N GLN 281.A OE1 no hydrogen 3.108 N/A GLN 281.A N THR 278.A OG1 no hydrogen 3.099 N/A ALA 282.A N THR 278.A O no hydrogen 2.806 N/A LEU 283.A N ALA 279.A O no hydrogen 3.060 N/A ALA 284.A N GLN 281.A O no hydrogen 3.074 N/A HIS 285.A N ALA 282.A O no hydrogen 3.000 N/A HIS 285.A NE2 ASP 263.A OD2 no hydrogen 2.806 N/A TYR 287.A N HIS 285.A ND1 no hydrogen 3.003 N/A TYR 287.A OH ASP 115.A OD1 no hydrogen 2.789 N/A PHE 288.A N HIS 285.A O no hydrogen 2.967 N/A ALA 289.A N ALA 286.A O no hydrogen 3.145 N/A GLN 290.A NE2 GLN 119.A OE1 no hydrogen 2.720 N/A TYR 291.A N PHE 288.A O no hydrogen 2.947 N/A TYR 291.A OH ASP 116.A OD1 no hydrogen 2.348 N/A HIS 292.A N PHE 288.A O no hydrogen 2.776 N/A HIS 292.A ND1 GLU 297.A OE2 no hydrogen 2.690 N/A ASP 293.A N GLU 297.A OE2 no hydrogen 3.328 N/A ASP 295.A N ASP 293.A OD1 no hydrogen 2.949 N/A ASP 296.A N ASP 293.A O no hydrogen 2.964 N/A ALA 300.A N SER 134.A OG no hydrogen 2.798 N/A GLN 305.A NE2 ASP 136.A O no hydrogen 2.739 N/A SER 306.A N ASP 304.A OD1 no hydrogen 3.029 N/A SER 306.A OG ASP 304.A OD1 no hydrogen 2.544 N/A SER 306.A OG ASP 304.A OD2 no hydrogen 3.553 N/A GLU 308.A N GLN 305.A O no hydrogen 2.969 N/A SER 309.A N SER 306.A O no hydrogen 3.236 N/A SER 309.A OG SER 306.A O no hydrogen 3.019 N/A ARG 310.A N PHE 307.A O no hydrogen 3.104 N/A ARG 310.A NH2 SER 306.A OG no hydrogen 2.969 N/A LEU 313.A N GLU 316.A OE1 no hydrogen 3.071 N/A GLU 316.A N LEU 313.A O no hydrogen 3.083 N/A TRP 317.A N LEU 313.A O no hydrogen 3.134 N/A LYS 318.A N ILE 314.A O no hydrogen 2.858 N/A LYS 318.A NZ PHE 95.A O no hydrogen 3.070 N/A LYS 318.A NZ ASN 96.A OD1 no hydrogen 3.405 N/A SER 319.A N ASP 315.A O no hydrogen 2.884 N/A LEU 320.A N GLU 316.A O no hydrogen 2.907 N/A THR 321.A N TRP 317.A O no hydrogen 2.821 N/A THR 321.A OG1 TRP 317.A O no hydrogen 2.795 N/A TYR 322.A N LYS 318.A O no hydrogen 2.867 N/A ASP 323.A N SER 319.A O no hydrogen 2.887 N/A GLU 324.A N LEU 320.A O no hydrogen 3.211 N/A VAL 325.A N THR 321.A O no hydrogen 2.900 N/A ILE 326.A N TYR 322.A O no hydrogen 2.928 N/A SER 327.A N ASP 323.A O no hydrogen 3.030 N/A SER 327.A OG ASP 323.A O no hydrogen 3.009 N/A SER 327.A OG GLU 324.A O no hydrogen 3.568 N/A PHE 328.A N VAL 325.A O no hydrogen 3.354 N/A