Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 6ii9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 7.A ND1 HIS 8.A O no hydrogen 2.789 N/A VAL 10.A N ASN 313.A OD1 no hydrogen 2.854 N/A THR 14.A N VAL 26.A O no hydrogen 2.946 N/A VAL 16.A N VAL 24.A O no hydrogen 2.936 N/A THR 18.A N GLU 21.A O no hydrogen 2.898 N/A THR 18.A OG1 GLU 21.A O no hydrogen 2.970 N/A GLU 21.A N THR 18.A OG1 no hydrogen 3.048 N/A GLY 23.A N ASN 17.A OD1 no hydrogen 2.663 N/A VAL 26.A N THR 14.A O no hydrogen 2.897 N/A VAL 27.A N MET 311.A O no hydrogen 2.984 N/A THR 30.A N LEU 307.A O no hydrogen 2.865 N/A THR 32.A N GLU 31.A OE2 no hydrogen 2.989 N/A THR 32.A N LEU 305.A O no hydrogen 3.265 N/A THR 32.A OG1 LEU 305.A O no hydrogen 2.264 N/A VAL 33.A N GLU 31.A OE2 no hydrogen 3.153 N/A GLU 34.A N PHE 285.A O no hydrogen 2.995 N/A ARG 35.A NH1 GLU 31.A OE1 no hydrogen 3.280 N/A ARG 35.A NH1 ARG 303.A O no hydrogen 3.366 N/A THR 36.A N GLU 34.A OE2 no hydrogen 2.822 N/A THR 36.A OG1 GLU 34.A OE2 no hydrogen 3.107 N/A ASN 37.A ND2 GLY 276.A O no hydrogen 3.514 N/A ILE 38.A N THR 278.A O no hydrogen 3.134 N/A ARG 40.A N ILE 38.A O no hydrogen 2.791 N/A ILE 41.A N GLN 263.A O no hydrogen 2.865 N/A CYS 42.A N THR 278.A OG1 no hydrogen 3.123 N/A CYS 42.A SG THR 278.A OG1 no hydrogen 3.605 N/A SER 43.A N ASP 265.A O no hydrogen 2.820 N/A SER 43.A OG ASP 265.A O no hydrogen 3.461 N/A LYS 44.A N CYS 268.A O no hydrogen 3.146 N/A LYS 44.A NZ ASN 267.A O no hydrogen 3.456 N/A LYS 46.A NZ GLY 270.A O no hydrogen 2.330 N/A LYS 46.A NZ ASP 271.A OD1 no hydrogen 2.986 N/A VAL 49.A N LEU 76.A O no hydrogen 3.229 N/A LEU 51.A N ILE 78.A O no hydrogen 3.103 N/A CYS 54.A N LEU 51.A O no hydrogen 3.355 N/A CYS 54.A SG GLY 55.A O no hydrogen 3.150 N/A LEU 57.A N ASP 85.A OD1 no hydrogen 3.017 N/A THR 59.A N LEU 56.A O no hydrogen 3.257 N/A THR 59.A OG1 LEU 56.A O no hydrogen 2.624 N/A ILE 60.A N LEU 57.A O no hydrogen 2.944 N/A GLY 62.A N GLY 58.A O no hydrogen 2.781 N/A GLN 65.A N GLN 65.A OE1 no hydrogen 2.427 N/A GLN 65.A NE2 SER 84.A O no hydrogen 2.863 N/A GLN 65.A NE2 VAL 86.A O no hydrogen 3.360 N/A CYS 66.A N PRO 63.A O no hydrogen 2.992 N/A CYS 66.A SG GLY 55.A O no hydrogen 3.577 N/A ASP 67.A N PRO 64.A O no hydrogen 2.965 N/A PHE 69.A N CYS 66.A O no hydrogen 2.985 N/A PHE 72.A N PHE 69.A O no hydrogen 3.181 N/A ALA 74.A N GLY 106.A O no hydrogen 3.120 N/A ASP 75.A N ARG 47.A O no hydrogen 2.844 N/A LEU 76.A N ARG 47.A O no hydrogen 3.030 N/A ILE 77.A N MET 256.A O no hydrogen 2.787 N/A ILE 78.A N VAL 49.A O no hydrogen 3.050 N/A GLU 79.A N ILE 258.A O no hydrogen 3.028 N/A ARG 80.A NE ASP 50.A OD1 no hydrogen 2.559 N/A ARG 80.A NH1 SER 260.A O no hydrogen 3.038 N/A ARG 80.A NH1 VAL 262.A O no hydrogen 3.218 N/A ARG 80.A NH2 ASP 50.A OD1 no hydrogen 3.096 N/A ARG 80.A NH2 ASP 50.A OD2 no hydrogen 2.922 N/A ARG 80.A NH2 VAL 262.A O no hydrogen 3.263 N/A GLU 82.A N GLU 82.A OE1 no hydrogen 2.761 N/A GLY 83.A N ARG 80.A O no hydrogen 3.414 N/A SER 84.A N GLN 53.A O no hydrogen 2.919 N/A SER 84.A OG VAL 86.A O no hydrogen 2.672 N/A CYS 87.A N TYR 137.A OH no hydrogen 3.182 N/A LYS 91.A N ILE 221.A O no hydrogen 3.292 N/A VAL 93.A N PHE 223.A O no hydrogen 2.950 N/A LEU 98.A N ASN 94.A O no hydrogen 3.280 N/A ARG 99.A N GLU 95.A O no hydrogen 2.904 N/A ARG 99.A NH1 GLU 95.A OE2 no hydrogen 2.958 N/A GLN 100.A N GLU 96.A O no hydrogen 2.872 N/A ILE 101.A N ALA 97.A O no hydrogen 2.927 N/A LEU 102.A N LEU 98.A O no hydrogen 2.931 N/A ARG 103.A N ARG 99.A O no hydrogen 2.862 N/A ARG 103.A NE GLU 79.A OE1 no hydrogen 2.621 N/A ARG 103.A NH2 GLU 79.A OE1 no hydrogen 3.375 N/A ARG 103.A NH2 GLU 96.A OE2 no hydrogen 3.081 N/A SER 105.A N LEU 102.A O no hydrogen 3.354 N/A SER 105.A OG LEU 102.A O no hydrogen 2.585 N/A SER 105.A OG GLY 107.A O no hydrogen 3.539 N/A GLY 106.A N SER 255.A OG no hydrogen 2.657 N/A GLY 107.A N SER 105.A OG no hydrogen 3.320 N/A ILE 108.A N PHE 72.A O no hydrogen 3.037 N/A ASP 109.A N PHE 250.A O no hydrogen 2.869 N/A LYS 110.A N GLU 71.A OE2 no hydrogen 3.013 N/A LYS 110.A NZ THR 59.A O no hydrogen 3.036 N/A LYS 110.A NZ LEU 70.A O no hydrogen 3.110 N/A LYS 110.A NZ GLU 139.A OE2 no hydrogen 2.695 N/A GLU 111.A N ALA 248.A O no hydrogen 2.942 N/A MET 113.A N ASP 246.A O no hydrogen 2.758 N/A ARG 121.A N LEU 144.A O no hydrogen 2.846 N/A ARG 121.A NH1 SER 145.A O no hydrogen 2.854 N/A ARG 121.A NH1 ASP 148.A OD1 no hydrogen 3.469 N/A ARG 121.A NH2 ASP 148.A OD1 no hydrogen 3.317 N/A THR 126.A N SER 135.A O no hydrogen 3.019 N/A ALA 128.A N THR 126.A OG1 no hydrogen 3.231 N/A ARG 131.A N GLY 133.A O no hydrogen 2.903 N/A ARG 131.A NE ASP 67.A OD2 no hydrogen 3.166 N/A ARG 131.A NH1 PHE 136.A O no hydrogen 2.381 N/A ARG 131.A NH2 GLY 62.A O no hydrogen 3.036 N/A ARG 131.A NH2 ASP 67.A OD1 no hydrogen 2.664 N/A ARG 131.A NH2 ASP 67.A OD2 no hydrogen 3.518 N/A SER 132.A OG ARG 131.A O no hydrogen 2.545 N/A SER 135.A N THR 126.A O no hydrogen 2.898 N/A PHE 136.A N SER 135.A OG no hydrogen 2.700 N/A TYR 137.A OH TYR 88.A O no hydrogen 2.595 N/A ALA 138.A N GLY 62.A O no hydrogen 2.605 N/A GLU 139.A N THR 61.A O no hydrogen 3.079 N/A LYS 141.A N ALA 244.A O no hydrogen 2.920 N/A LYS 141.A NZ ASP 246.A OD2 no hydrogen 3.441 N/A TRP 142.A NE1 TYR 186.A OH no hydrogen 2.629 N/A LEU 143.A N PHE 242.A O no hydrogen 3.088 N/A LEU 144.A N ARG 121.A O no hydrogen 2.849 N/A SER 145.A N LEU 185.A O no hydrogen 2.882 N/A SER 145.A OG ALA 150.A O no hydrogen 3.104 N/A SER 145.A OG LEU 185.A O no hydrogen 3.230 N/A ASN 146.A ND2 ASN 146.A O no hydrogen 3.082 N/A ASN 149.A N LYS 184.A O no hydrogen 3.072 N/A ALA 150.A N THR 147.A O no hydrogen 2.993 N/A GLN 154.A NE2 SER 237.A OG no hydrogen 3.376 N/A MET 155.A N PHE 238.A O no hydrogen 2.945 N/A THR 156.A OG1 MET 155.A O no hydrogen 2.963 N/A LYS 157.A N PHE 236.A O no hydrogen 2.875 N/A LYS 157.A NZ THR 116.A O no hydrogen 2.398 N/A SER 158.A OG THR 235.A OG1 no hydrogen 2.874 N/A TYR 159.A N VAL 234.A O no hydrogen 2.914 N/A TYR 159.A OH GLU 111.A OE2 no hydrogen 3.132 N/A ASN 161.A N ASP 232.A O no hydrogen 2.918 N/A ASN 161.A ND2 SER 165.A O no hydrogen 3.344 N/A ASN 161.A ND2 LEU 228.A O no hydrogen 2.964 N/A ASN 161.A ND2 ASN 229.A O no hydrogen 3.148 N/A ARG 163.A N ASN 161.A OD1 no hydrogen 3.258 N/A ARG 163.A NH1 GLU 111.A OE1 no hydrogen 2.901 N/A ARG 163.A NH2 ASP 109.A OD2 no hydrogen 2.713 N/A SER 165.A OG PRO 166.A O no hydrogen 3.564 N/A ALA 167.A N LEU 228.A O no hydrogen 2.922 N/A LEU 168.A N SER 249.A O no hydrogen 2.671 N/A ILE 169.A N LEU 226.A O no hydrogen 2.900 N/A TRP 171.A N HIS 224.A O no hydrogen 2.941 N/A GLY 172.A N ILE 243.A O no hydrogen 2.932 N/A ILE 173.A N ASP 222.A O no hydrogen 2.918 N/A HIS 174.A N ALA 241.A O no hydrogen 3.302 N/A HIS 174.A ND1 TYR 186.A OH no hydrogen 2.268 N/A HIS 174.A NE2 TYR 88.A OH no hydrogen 3.171 N/A HIS 175.A N ARG 220.A O no hydrogen 2.827 N/A VAL 177.A N GLU 181.A OE1 no hydrogen 2.549 N/A GLU 181.A N SER 178.A OG no hydrogen 2.878 N/A GLN 182.A N SER 178.A O no hydrogen 2.930 N/A THR 183.A N THR 179.A O no hydrogen 2.954 N/A THR 183.A OG1 ALA 180.A O no hydrogen 2.942 N/A LYS 184.A N ALA 180.A O no hydrogen 2.945 N/A LYS 184.A N GLU 181.A O no hydrogen 2.913 N/A LEU 185.A N GLU 181.A O no hydrogen 2.955 N/A TYR 186.A N GLN 182.A O no hydrogen 2.943 N/A TYR 186.A OH HIS 174.A ND1 no hydrogen 2.268 N/A LYS 191.A NZ TYR 186.A O no hydrogen 2.864 N/A LYS 191.A NZ SER 188.A O no hydrogen 3.544 N/A LYS 191.A NZ ASN 239.A O no hydrogen 3.152 N/A VAL 193.A N PHE 204.A O no hydrogen 3.026 N/A THR 194.A N SER 237.A O no hydrogen 2.883 N/A VAL 195.A N GLN 202.A O no hydrogen 2.891 N/A GLY 196.A N THR 235.A O no hydrogen 2.927 N/A SER 197.A N TYR 200.A O no hydrogen 2.880 N/A SER 197.A OG ASN 199.A OD1 no hydrogen 3.465 N/A SER 198.A OG ASP 232.A OD1 no hydrogen 2.602 N/A SER 198.A OG ASP 232.A OD2 no hydrogen 3.179 N/A TYR 200.A N SER 197.A O no hydrogen 3.518 N/A GLN 202.A N VAL 195.A O no hydrogen 3.311 N/A PHE 204.A N VAL 193.A O no hydrogen 2.713 N/A SER 207.A N HIS 175.A ND1 no hydrogen 2.743 N/A SER 207.A OG HIS 175.A ND1 no hydrogen 2.983 N/A SER 207.A OG SER 207.A O no hydrogen 2.692 N/A GLY 209.A N SER 176.A O no hydrogen 3.037 N/A ARG 211.A N SER 218.A O no hydrogen 3.033 N/A ARG 211.A NH1 SER 207.A O no hydrogen 2.929 N/A ARG 211.A NH1 GLY 209.A O no hydrogen 3.434 N/A ARG 211.A NH2 SER 207.A O no hydrogen 3.344 N/A ARG 211.A NH2 SER 207.A OG no hydrogen 3.235 N/A VAL 214.A N LEU 217.A O no hydrogen 2.982 N/A LEU 217.A N VAL 214.A O no hydrogen 3.093 N/A ARG 220.A N HIS 175.A O no hydrogen 2.966 N/A ARG 220.A NH1 LEU 217.A O no hydrogen 3.460 N/A ARG 220.A NH1 GLY 219.A O no hydrogen 3.425 N/A ARG 220.A NH2 PRO 212.A O no hydrogen 2.449 N/A ILE 221.A N PRO 89.A O no hydrogen 3.088 N/A ASP 222.A N ILE 173.A O no hydrogen 2.873 N/A PHE 223.A N LYS 91.A O no hydrogen 3.205 N/A HIS 224.A N TRP 171.A O no hydrogen 2.930 N/A TRP 225.A NE1 VAL 93.A O no hydrogen 2.670 N/A LEU 226.A N ILE 169.A O no hydrogen 2.861 N/A LEU 228.A N ALA 167.A O no hydrogen 2.892 N/A ASN 231.A N ASN 161.A O no hydrogen 2.773 N/A ASP 232.A N ASN 229.A O no hydrogen 3.181 N/A THR 233.A N ASP 232.A OD1 no hydrogen 2.554 N/A VAL 234.A N TYR 159.A O no hydrogen 2.869 N/A THR 235.A N GLY 196.A O no hydrogen 2.854 N/A THR 235.A OG1 SER 158.A OG no hydrogen 2.874 N/A PHE 236.A N LYS 157.A O no hydrogen 2.839 N/A SER 237.A N THR 194.A O no hydrogen 2.938 N/A PHE 238.A N MET 155.A O no hydrogen 2.958 N/A ILE 243.A N GLY 172.A O no hydrogen 2.831 N/A ALA 244.A N LYS 141.A O no hydrogen 2.920 N/A ASP 246.A N GLU 139.A O no hydrogen 2.845 N/A ARG 247.A NH1 GLU 139.A OE1 no hydrogen 2.844 N/A ALA 248.A N GLU 111.A O no hydrogen 2.877 N/A SER 249.A N LEU 168.A O no hydrogen 3.282 N/A PHE 250.A N ASP 109.A O no hydrogen 2.855 N/A ARG 252.A N GLY 107.A O no hydrogen 3.133 N/A ARG 252.A NE PHE 72.A O no hydrogen 3.126 N/A ARG 252.A NE ILE 108.A O no hydrogen 3.186 N/A ARG 252.A NH2 GLU 71.A O no hydrogen 2.645 N/A ARG 252.A NH2 PHE 72.A O no hydrogen 3.447 N/A GLY 253.A N SER 105.A O no hydrogen 2.815 N/A SER 255.A OG ARG 103.A O no hydrogen 2.675 N/A MET 256.A N ASP 75.A O no hydrogen 2.921 N/A ILE 258.A N ILE 77.A O no hydrogen 2.991 N/A SER 260.A N GLU 79.A O no hydrogen 3.353 N/A SER 260.A OG SER 275.A O no hydrogen 3.379 N/A GLY 261.A N SER 275.A O no hydrogen 3.246 N/A VAL 262.A N SER 260.A OG no hydrogen 3.286 N/A ASP 265.A N ILE 41.A O no hydrogen 2.632 N/A ASN 267.A N ASP 265.A OD1 no hydrogen 3.362 N/A CYS 272.A SG VAL 293.A O no hydrogen 3.859 N/A TYR 273.A N VAL 293.A O no hydrogen 2.845 N/A TYR 273.A OH CYS 42.A O no hydrogen 2.500 N/A HIS 274.A N GLY 277.A O no hydrogen 2.981 N/A GLY 276.A N HIS 274.A ND1 no hydrogen 3.146 N/A GLY 277.A N HIS 274.A O no hydrogen 3.189 N/A THR 278.A N ILE 38.A O no hydrogen 3.031 N/A THR 278.A OG1 ARG 40.A O no hydrogen 2.460 N/A ILE 279.A N CYS 272.A O no hydrogen 2.822 N/A SER 281.A OG GLU 34.A OE1 no hydrogen 2.854 N/A LEU 283.A N SER 281.A OG no hydrogen 3.068 N/A GLN 286.A N ARG 298.A O no hydrogen 3.090 N/A GLN 286.A NE2 ASP 289.A O no hydrogen 2.977 N/A GLN 286.A NE2 PRO 297.A O no hydrogen 3.523 N/A ASN 287.A N GLU 34.A O no hydrogen 3.276 N/A ASN 287.A ND2 VAL 300.A O no hydrogen 2.569 N/A ASN 287.A ND2 LYS 301.A O no hydrogen 2.877 N/A ILE 288.A N GLN 286.A OE1 no hydrogen 2.784 N/A ASP 289.A N GLN 286.A OE1 no hydrogen 3.070 N/A ARG 291.A N ASP 289.A OD1 no hydrogen 3.299 N/A ALA 292.A N ASP 289.A O no hydrogen 3.367 N/A VAL 293.A N TYR 273.A O no hydrogen 3.001 N/A CYS 296.A SG VAL 293.A O no hydrogen 3.120 N/A CYS 296.A SG GLY 294.A O no hydrogen 3.266 N/A ARG 298.A N PRO 284.A O no hydrogen 3.300 N/A VAL 300.A N GLN 286.A O no hydrogen 3.049 N/A GLN 302.A N GLN 302.A OE1 no hydrogen 2.645 N/A SER 304.A OG GLU 31.A OE1 no hydrogen 2.386 N/A SER 304.A OG GLU 31.A OE2 no hydrogen 3.300 N/A LEU 305.A N GLU 31.A OE2 no hydrogen 2.894 N/A LEU 307.A N THR 30.A O no hydrogen 2.882 N/A THR 309.A N ASN 28.A O no hydrogen 2.858 N/A THR 309.A OG1 ASN 28.A O no hydrogen 2.631 N/A ASN 313.A N GLU 25.A O no hydrogen 3.047 N/A ASN 313.A ND2 VAL 10.A O no hydrogen 2.714 N/A